Search of human proteins with 215820650

Search of human proteins with 215820650

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|215820650 StAR-related lipid transfer (START) domain
containing 8 isoform a [Homo sapiens]
         (1103 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|215820650 StAR-related lipid transfer (START) domain containi...  2249   0.0  
gi|215820652 StAR-related lipid transfer (START) domain containi...  2082   0.0  
gi|31543659 StAR-related lipid transfer (START) domain containin...  2082   0.0  
gi|41281907 StAR-related lipid transfer (START) domain containin...   683   0.0  
gi|16445031 StAR-related lipid transfer (START) domain containin...   683   0.0  
gi|41281898 StAR-related lipid transfer (START) domain containin...   683   0.0  
gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]        653   0.0  
gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]        653   0.0  
gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]    90   1e-17
gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi...    90   1e-17
gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi...    90   1e-17
gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]            81   5e-15
gi|194272142 myosin IXB isoform 2 [Homo sapiens]                       81   6e-15
gi|33356170 myosin IXB isoform 1 [Homo sapiens]                        81   6e-15
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                79   3e-14
gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]            77   7e-14
gi|40255080 hypothetical protein LOC158763 [Homo sapiens]              76   2e-13
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ...    76   2e-13
gi|59710113 Rho GTPase activating protein 28 isoform a [Homo sap...    76   2e-13
gi|59710111 Rho GTPase activating protein 28 isoform b [Homo sap...    76   2e-13
gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Hom...    74   8e-13
gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Hom...    74   8e-13
gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [H...    74   8e-13
gi|156119615 myosin IXA [Homo sapiens]                                 73   1e-12
gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo sap...    71   5e-12
gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap...    71   5e-12
gi|7661858 Rho GTPase activating protein 11A isoform 1 [Homo sap...    70   8e-12
gi|40788018 Rho GTPase activating protein 11A isoform 2 [Homo sa...    70   8e-12
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]         70   1e-11
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]         70   1e-11

>gi|215820650 StAR-related lipid transfer (START) domain containing 8
            isoform a [Homo sapiens]
          Length = 1103

 Score = 2249 bits (5827), Expect = 0.0
 Identities = 1103/1103 (100%), Positives = 1103/1103 (100%)

Query: 1    MPLLDVFWSCFRKVKCFPLLQVKKNAEAEAKRACEWLQATGFPQYVQLFEEGSFPLDIGS 60
            MPLLDVFWSCFRKVKCFPLLQVKKNAEAEAKRACEWLQATGFPQYVQLFEEGSFPLDIGS
Sbjct: 1    MPLLDVFWSCFRKVKCFPLLQVKKNAEAEAKRACEWLQATGFPQYVQLFEEGSFPLDIGS 60

Query: 61   VKKNHGFLDEDSLGALCRRLMTLNNCASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQE 120
            VKKNHGFLDEDSLGALCRRLMTLNNCASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQE
Sbjct: 61   VKKNHGFLDEDSLGALCRRLMTLNNCASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQE 120

Query: 121  SKCWSPMGSSDLLAPPSPGLPATSSCESVLTELSATSLPVITVSLPPEPADLPLPGRAPS 180
            SKCWSPMGSSDLLAPPSPGLPATSSCESVLTELSATSLPVITVSLPPEPADLPLPGRAPS
Sbjct: 121  SKCWSPMGSSDLLAPPSPGLPATSSCESVLTELSATSLPVITVSLPPEPADLPLPGRAPS 180

Query: 181  SSDRPLLSPTQGQEGPQDKAKKRHRNRSFLKHLESLRRKEKSGSQQAEPKHSPATSEKVS 240
            SSDRPLLSPTQGQEGPQDKAKKRHRNRSFLKHLESLRRKEKSGSQQAEPKHSPATSEKVS
Sbjct: 181  SSDRPLLSPTQGQEGPQDKAKKRHRNRSFLKHLESLRRKEKSGSQQAEPKHSPATSEKVS 240

Query: 241  KASSFRSCRGFLSAGFYRAKNWAATSAGGSGANTRKAWEAWPVASFRHPQWTHRGDCLVH 300
            KASSFRSCRGFLSAGFYRAKNWAATSAGGSGANTRKAWEAWPVASFRHPQWTHRGDCLVH
Sbjct: 241  KASSFRSCRGFLSAGFYRAKNWAATSAGGSGANTRKAWEAWPVASFRHPQWTHRGDCLVH 300

Query: 301  VPGDHKPGTFPRSLSIESLCPEDGHRLADWQPGRRWGCEGRRGSCGSTGSHASTYDNLPE 360
            VPGDHKPGTFPRSLSIESLCPEDGHRLADWQPGRRWGCEGRRGSCGSTGSHASTYDNLPE
Sbjct: 301  VPGDHKPGTFPRSLSIESLCPEDGHRLADWQPGRRWGCEGRRGSCGSTGSHASTYDNLPE 360

Query: 361  LYPAEPVMVGAEAEDEDDEESGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGDEEE 420
            LYPAEPVMVGAEAEDEDDEESGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGDEEE
Sbjct: 361  LYPAEPVMVGAEAEDEDDEESGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGDEEE 420

Query: 421  EEATSSVEIATVEVKCQAEALSQMEVPAHGESPAWAQAEVQPAVLAPAQAPAEAEPVAQE 480
            EEATSSVEIATVEVKCQAEALSQMEVPAHGESPAWAQAEVQPAVLAPAQAPAEAEPVAQE
Sbjct: 421  EEATSSVEIATVEVKCQAEALSQMEVPAHGESPAWAQAEVQPAVLAPAQAPAEAEPVAQE 480

Query: 481  EAEAPAPAPAPAPAQDSEQEAHSGGEPTFASSLSVEEGHSISDTVASSSELDSSGNSMNE 540
            EAEAPAPAPAPAPAQDSEQEAHSGGEPTFASSLSVEEGHSISDTVASSSELDSSGNSMNE
Sbjct: 481  EAEAPAPAPAPAPAQDSEQEAHSGGEPTFASSLSVEEGHSISDTVASSSELDSSGNSMNE 540

Query: 541  AEAAGPLAGLQASMPRERRDSGVGASLTRPCRKLRWHSFQNSHRPSLNSESLEINRQFAG 600
            AEAAGPLAGLQASMPRERRDSGVGASLTRPCRKLRWHSFQNSHRPSLNSESLEINRQFAG
Sbjct: 541  AEAAGPLAGLQASMPRERRDSGVGASLTRPCRKLRWHSFQNSHRPSLNSESLEINRQFAG 600

Query: 601  QINLLHKGSLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQHVFGVPPLIHVQR 660
            QINLLHKGSLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQHVFGVPPLIHVQR
Sbjct: 601  QINLLHKGSLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQHVFGVPPLIHVQR 660

Query: 661  TGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDV 720
            TGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDV
Sbjct: 661  TGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDV 720

Query: 721  ADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLY 780
            ADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLY
Sbjct: 721  ADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLY 780

Query: 781  FLSDIASAEENQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPGPRDLSDNM 840
            FLSDIASAEENQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPGPRDLSDNM
Sbjct: 781  FLSDIASAEENQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPGPRDLSDNM 840

Query: 841  AATQGLSHMISDCKKLFQVPQDMVLQLCSSYSAAELSPPGPALAELRQAQAAGVSLSLYM 900
            AATQGLSHMISDCKKLFQVPQDMVLQLCSSYSAAELSPPGPALAELRQAQAAGVSLSLYM
Sbjct: 841  AATQGLSHMISDCKKLFQVPQDMVLQLCSSYSAAELSPPGPALAELRQAQAAGVSLSLYM 900

Query: 901  EENIQDLLRDAAERFKGWMSVPGPQHTELACRKAPDGHPLRLWKASTEVAAPPAVVLHRV 960
            EENIQDLLRDAAERFKGWMSVPGPQHTELACRKAPDGHPLRLWKASTEVAAPPAVVLHRV
Sbjct: 901  EENIQDLLRDAAERFKGWMSVPGPQHTELACRKAPDGHPLRLWKASTEVAAPPAVVLHRV 960

Query: 961  LRERALWDEDLLRAQVLEALMPGVELYHYVTDSMAPHPCRDFVVLRMWRSDLPRGGCLLV 1020
            LRERALWDEDLLRAQVLEALMPGVELYHYVTDSMAPHPCRDFVVLRMWRSDLPRGGCLLV
Sbjct: 961  LRERALWDEDLLRAQVLEALMPGVELYHYVTDSMAPHPCRDFVVLRMWRSDLPRGGCLLV 1020

Query: 1021 SQSLDPEQPVPESGVRALMLTSQYLMEPCGLGRSRLTHICRADLRGRSPDWYNKVFGHLC 1080
            SQSLDPEQPVPESGVRALMLTSQYLMEPCGLGRSRLTHICRADLRGRSPDWYNKVFGHLC
Sbjct: 1021 SQSLDPEQPVPESGVRALMLTSQYLMEPCGLGRSRLTHICRADLRGRSPDWYNKVFGHLC 1080

Query: 1081 AMEVAKIRDSFPTLQAAGPETKL 1103
            AMEVAKIRDSFPTLQAAGPETKL
Sbjct: 1081 AMEVAKIRDSFPTLQAAGPETKL 1103


>gi|215820652 StAR-related lipid transfer (START) domain containing 8
            isoform b [Homo sapiens]
          Length = 1023

 Score = 2082 bits (5395), Expect = 0.0
 Identities = 1023/1023 (100%), Positives = 1023/1023 (100%)

Query: 81   MTLNNCASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLLAPPSPGL 140
            MTLNNCASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLLAPPSPGL
Sbjct: 1    MTLNNCASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLLAPPSPGL 60

Query: 141  PATSSCESVLTELSATSLPVITVSLPPEPADLPLPGRAPSSSDRPLLSPTQGQEGPQDKA 200
            PATSSCESVLTELSATSLPVITVSLPPEPADLPLPGRAPSSSDRPLLSPTQGQEGPQDKA
Sbjct: 61   PATSSCESVLTELSATSLPVITVSLPPEPADLPLPGRAPSSSDRPLLSPTQGQEGPQDKA 120

Query: 201  KKRHRNRSFLKHLESLRRKEKSGSQQAEPKHSPATSEKVSKASSFRSCRGFLSAGFYRAK 260
            KKRHRNRSFLKHLESLRRKEKSGSQQAEPKHSPATSEKVSKASSFRSCRGFLSAGFYRAK
Sbjct: 121  KKRHRNRSFLKHLESLRRKEKSGSQQAEPKHSPATSEKVSKASSFRSCRGFLSAGFYRAK 180

Query: 261  NWAATSAGGSGANTRKAWEAWPVASFRHPQWTHRGDCLVHVPGDHKPGTFPRSLSIESLC 320
            NWAATSAGGSGANTRKAWEAWPVASFRHPQWTHRGDCLVHVPGDHKPGTFPRSLSIESLC
Sbjct: 181  NWAATSAGGSGANTRKAWEAWPVASFRHPQWTHRGDCLVHVPGDHKPGTFPRSLSIESLC 240

Query: 321  PEDGHRLADWQPGRRWGCEGRRGSCGSTGSHASTYDNLPELYPAEPVMVGAEAEDEDDEE 380
            PEDGHRLADWQPGRRWGCEGRRGSCGSTGSHASTYDNLPELYPAEPVMVGAEAEDEDDEE
Sbjct: 241  PEDGHRLADWQPGRRWGCEGRRGSCGSTGSHASTYDNLPELYPAEPVMVGAEAEDEDDEE 300

Query: 381  SGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGDEEEEEATSSVEIATVEVKCQAEA 440
            SGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGDEEEEEATSSVEIATVEVKCQAEA
Sbjct: 301  SGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGDEEEEEATSSVEIATVEVKCQAEA 360

Query: 441  LSQMEVPAHGESPAWAQAEVQPAVLAPAQAPAEAEPVAQEEAEAPAPAPAPAPAQDSEQE 500
            LSQMEVPAHGESPAWAQAEVQPAVLAPAQAPAEAEPVAQEEAEAPAPAPAPAPAQDSEQE
Sbjct: 361  LSQMEVPAHGESPAWAQAEVQPAVLAPAQAPAEAEPVAQEEAEAPAPAPAPAPAQDSEQE 420

Query: 501  AHSGGEPTFASSLSVEEGHSISDTVASSSELDSSGNSMNEAEAAGPLAGLQASMPRERRD 560
            AHSGGEPTFASSLSVEEGHSISDTVASSSELDSSGNSMNEAEAAGPLAGLQASMPRERRD
Sbjct: 421  AHSGGEPTFASSLSVEEGHSISDTVASSSELDSSGNSMNEAEAAGPLAGLQASMPRERRD 480

Query: 561  SGVGASLTRPCRKLRWHSFQNSHRPSLNSESLEINRQFAGQINLLHKGSLLRLTAFMEKY 620
            SGVGASLTRPCRKLRWHSFQNSHRPSLNSESLEINRQFAGQINLLHKGSLLRLTAFMEKY
Sbjct: 481  SGVGASLTRPCRKLRWHSFQNSHRPSLNSESLEINRQFAGQINLLHKGSLLRLTAFMEKY 540

Query: 621  TVPHKQGWVWSMPKFMRRNKTPDYRGQHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQC 680
            TVPHKQGWVWSMPKFMRRNKTPDYRGQHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQC
Sbjct: 541  TVPHKQGWVWSMPKFMRRNKTPDYRGQHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQC 600

Query: 681  LDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKL 740
            LDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKL
Sbjct: 601  LDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKL 660

Query: 741  TTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSDIASAEENQMTAGNLAV 800
            TTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSDIASAEENQMTAGNLAV
Sbjct: 661  TTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSDIASAEENQMTAGNLAV 720

Query: 801  CLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPGPRDLSDNMAATQGLSHMISDCKKLFQVP 860
            CLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPGPRDLSDNMAATQGLSHMISDCKKLFQVP
Sbjct: 721  CLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPGPRDLSDNMAATQGLSHMISDCKKLFQVP 780

Query: 861  QDMVLQLCSSYSAAELSPPGPALAELRQAQAAGVSLSLYMEENIQDLLRDAAERFKGWMS 920
            QDMVLQLCSSYSAAELSPPGPALAELRQAQAAGVSLSLYMEENIQDLLRDAAERFKGWMS
Sbjct: 781  QDMVLQLCSSYSAAELSPPGPALAELRQAQAAGVSLSLYMEENIQDLLRDAAERFKGWMS 840

Query: 921  VPGPQHTELACRKAPDGHPLRLWKASTEVAAPPAVVLHRVLRERALWDEDLLRAQVLEAL 980
            VPGPQHTELACRKAPDGHPLRLWKASTEVAAPPAVVLHRVLRERALWDEDLLRAQVLEAL
Sbjct: 841  VPGPQHTELACRKAPDGHPLRLWKASTEVAAPPAVVLHRVLRERALWDEDLLRAQVLEAL 900

Query: 981  MPGVELYHYVTDSMAPHPCRDFVVLRMWRSDLPRGGCLLVSQSLDPEQPVPESGVRALML 1040
            MPGVELYHYVTDSMAPHPCRDFVVLRMWRSDLPRGGCLLVSQSLDPEQPVPESGVRALML
Sbjct: 901  MPGVELYHYVTDSMAPHPCRDFVVLRMWRSDLPRGGCLLVSQSLDPEQPVPESGVRALML 960

Query: 1041 TSQYLMEPCGLGRSRLTHICRADLRGRSPDWYNKVFGHLCAMEVAKIRDSFPTLQAAGPE 1100
            TSQYLMEPCGLGRSRLTHICRADLRGRSPDWYNKVFGHLCAMEVAKIRDSFPTLQAAGPE
Sbjct: 961  TSQYLMEPCGLGRSRLTHICRADLRGRSPDWYNKVFGHLCAMEVAKIRDSFPTLQAAGPE 1020

Query: 1101 TKL 1103
            TKL
Sbjct: 1021 TKL 1023


>gi|31543659 StAR-related lipid transfer (START) domain containing 8
            isoform b [Homo sapiens]
          Length = 1023

 Score = 2082 bits (5395), Expect = 0.0
 Identities = 1023/1023 (100%), Positives = 1023/1023 (100%)

Query: 81   MTLNNCASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLLAPPSPGL 140
            MTLNNCASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLLAPPSPGL
Sbjct: 1    MTLNNCASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLLAPPSPGL 60

Query: 141  PATSSCESVLTELSATSLPVITVSLPPEPADLPLPGRAPSSSDRPLLSPTQGQEGPQDKA 200
            PATSSCESVLTELSATSLPVITVSLPPEPADLPLPGRAPSSSDRPLLSPTQGQEGPQDKA
Sbjct: 61   PATSSCESVLTELSATSLPVITVSLPPEPADLPLPGRAPSSSDRPLLSPTQGQEGPQDKA 120

Query: 201  KKRHRNRSFLKHLESLRRKEKSGSQQAEPKHSPATSEKVSKASSFRSCRGFLSAGFYRAK 260
            KKRHRNRSFLKHLESLRRKEKSGSQQAEPKHSPATSEKVSKASSFRSCRGFLSAGFYRAK
Sbjct: 121  KKRHRNRSFLKHLESLRRKEKSGSQQAEPKHSPATSEKVSKASSFRSCRGFLSAGFYRAK 180

Query: 261  NWAATSAGGSGANTRKAWEAWPVASFRHPQWTHRGDCLVHVPGDHKPGTFPRSLSIESLC 320
            NWAATSAGGSGANTRKAWEAWPVASFRHPQWTHRGDCLVHVPGDHKPGTFPRSLSIESLC
Sbjct: 181  NWAATSAGGSGANTRKAWEAWPVASFRHPQWTHRGDCLVHVPGDHKPGTFPRSLSIESLC 240

Query: 321  PEDGHRLADWQPGRRWGCEGRRGSCGSTGSHASTYDNLPELYPAEPVMVGAEAEDEDDEE 380
            PEDGHRLADWQPGRRWGCEGRRGSCGSTGSHASTYDNLPELYPAEPVMVGAEAEDEDDEE
Sbjct: 241  PEDGHRLADWQPGRRWGCEGRRGSCGSTGSHASTYDNLPELYPAEPVMVGAEAEDEDDEE 300

Query: 381  SGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGDEEEEEATSSVEIATVEVKCQAEA 440
            SGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGDEEEEEATSSVEIATVEVKCQAEA
Sbjct: 301  SGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGDEEEEEATSSVEIATVEVKCQAEA 360

Query: 441  LSQMEVPAHGESPAWAQAEVQPAVLAPAQAPAEAEPVAQEEAEAPAPAPAPAPAQDSEQE 500
            LSQMEVPAHGESPAWAQAEVQPAVLAPAQAPAEAEPVAQEEAEAPAPAPAPAPAQDSEQE
Sbjct: 361  LSQMEVPAHGESPAWAQAEVQPAVLAPAQAPAEAEPVAQEEAEAPAPAPAPAPAQDSEQE 420

Query: 501  AHSGGEPTFASSLSVEEGHSISDTVASSSELDSSGNSMNEAEAAGPLAGLQASMPRERRD 560
            AHSGGEPTFASSLSVEEGHSISDTVASSSELDSSGNSMNEAEAAGPLAGLQASMPRERRD
Sbjct: 421  AHSGGEPTFASSLSVEEGHSISDTVASSSELDSSGNSMNEAEAAGPLAGLQASMPRERRD 480

Query: 561  SGVGASLTRPCRKLRWHSFQNSHRPSLNSESLEINRQFAGQINLLHKGSLLRLTAFMEKY 620
            SGVGASLTRPCRKLRWHSFQNSHRPSLNSESLEINRQFAGQINLLHKGSLLRLTAFMEKY
Sbjct: 481  SGVGASLTRPCRKLRWHSFQNSHRPSLNSESLEINRQFAGQINLLHKGSLLRLTAFMEKY 540

Query: 621  TVPHKQGWVWSMPKFMRRNKTPDYRGQHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQC 680
            TVPHKQGWVWSMPKFMRRNKTPDYRGQHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQC
Sbjct: 541  TVPHKQGWVWSMPKFMRRNKTPDYRGQHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQC 600

Query: 681  LDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKL 740
            LDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKL
Sbjct: 601  LDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKL 660

Query: 741  TTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSDIASAEENQMTAGNLAV 800
            TTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSDIASAEENQMTAGNLAV
Sbjct: 661  TTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSDIASAEENQMTAGNLAV 720

Query: 801  CLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPGPRDLSDNMAATQGLSHMISDCKKLFQVP 860
            CLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPGPRDLSDNMAATQGLSHMISDCKKLFQVP
Sbjct: 721  CLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPGPRDLSDNMAATQGLSHMISDCKKLFQVP 780

Query: 861  QDMVLQLCSSYSAAELSPPGPALAELRQAQAAGVSLSLYMEENIQDLLRDAAERFKGWMS 920
            QDMVLQLCSSYSAAELSPPGPALAELRQAQAAGVSLSLYMEENIQDLLRDAAERFKGWMS
Sbjct: 781  QDMVLQLCSSYSAAELSPPGPALAELRQAQAAGVSLSLYMEENIQDLLRDAAERFKGWMS 840

Query: 921  VPGPQHTELACRKAPDGHPLRLWKASTEVAAPPAVVLHRVLRERALWDEDLLRAQVLEAL 980
            VPGPQHTELACRKAPDGHPLRLWKASTEVAAPPAVVLHRVLRERALWDEDLLRAQVLEAL
Sbjct: 841  VPGPQHTELACRKAPDGHPLRLWKASTEVAAPPAVVLHRVLRERALWDEDLLRAQVLEAL 900

Query: 981  MPGVELYHYVTDSMAPHPCRDFVVLRMWRSDLPRGGCLLVSQSLDPEQPVPESGVRALML 1040
            MPGVELYHYVTDSMAPHPCRDFVVLRMWRSDLPRGGCLLVSQSLDPEQPVPESGVRALML
Sbjct: 901  MPGVELYHYVTDSMAPHPCRDFVVLRMWRSDLPRGGCLLVSQSLDPEQPVPESGVRALML 960

Query: 1041 TSQYLMEPCGLGRSRLTHICRADLRGRSPDWYNKVFGHLCAMEVAKIRDSFPTLQAAGPE 1100
            TSQYLMEPCGLGRSRLTHICRADLRGRSPDWYNKVFGHLCAMEVAKIRDSFPTLQAAGPE
Sbjct: 961  TSQYLMEPCGLGRSRLTHICRADLRGRSPDWYNKVFGHLCAMEVAKIRDSFPTLQAAGPE 1020

Query: 1101 TKL 1103
            TKL
Sbjct: 1021 TKL 1023


>gi|41281907 StAR-related lipid transfer (START) domain containing 13
            isoform beta [Homo sapiens]
          Length = 1105

 Score =  683 bits (1762), Expect = 0.0
 Identities = 353/607 (58%), Positives = 452/607 (74%), Gaps = 20/607 (3%)

Query: 505  GEP---TFASSLSVE---EGHSISDTVASSSELDSSGNSMNEAEAAGPLAGLQASMPRER 558
            GEP   TF S   +    EG+S+S+   + S+++    S+NE+E  G          R+R
Sbjct: 511  GEPGLSTFPSPNQITLDFEGNSVSEGRTTPSDVERDVTSLNESEPPGV---------RDR 561

Query: 559  RDSGVGASLTRPCRKLRWHSFQNSHRPSLNSESLEINRQFAGQINLLHKGSLLRLTAFME 618
            RDSGVGASLTRP R+LRW+SFQ SH+P     S  I+ Q A Q++LL + SLLRLTA ME
Sbjct: 562  RDSGVGASLTRPNRRLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQRFSLLRLTAIME 621

Query: 619  KYTVPHKQGWVWSMPKFMRRNKTPDYRGQHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRS 678
            K+++ +K GW WS+PKFM+R K PDY+ + VFGVP ++HVQRTGQPLPQSIQQA+RYLRS
Sbjct: 622  KHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVHVQRTGQPLPQSIQQALRYLRS 681

Query: 679  QCLDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTS 738
             CLDQVG+FRKSGVKSRI  LRQMNE  P+NV YE QSAYDVAD++KQ+FRDLPEP+FT+
Sbjct: 682  NCLDQVGLFRKSGVKSRIHALRQMNENFPENVNYEDQSAYDVADMVKQFFRDLPEPLFTN 741

Query: 739  KLTTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSDIAS-AEENQMTAGN 797
            KL+ TFL IYQ + K+Q L A QAA LLL DENREVLQTLL FL+D+ +  EENQMT  N
Sbjct: 742  KLSETFLHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEENQMTPMN 801

Query: 798  LAVCLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPGPRDLSDNMAATQGLSHMISDCKKLF 857
            LAVCLAPS+FHLN+ KK+S SPR+  K+   G+P  +DL++N+AA QGL+HMI +C +LF
Sbjct: 802  LAVCLAPSLFHLNLLKKES-SPRVIQKKYATGKPDQKDLNENLAAAQGLAHMIMECDRLF 860

Query: 858  QVPQDMVLQLCSSYSAAELSPPGPALAEL-RQAQAAGVSLSLYMEENIQDLLRDAAERFK 916
            +VP ++V Q  +SY  AE+    P L EL  Q + +G +   Y+   IQ L ++A E+FK
Sbjct: 861  EVPHELVAQSRNSYVEAEIHV--PTLEELGTQLEESGATFHTYLNHLIQGLQKEAKEKFK 918

Query: 917  GWMSVPGPQHTELACRKAPDGHPLRLWKASTEVAAPPAVVLHRVLRERALWDEDLLRAQV 976
            GW++     +T+LA +K  DG+PL+LWKAS EV APP+VVL+RVLRER LWDED ++ +V
Sbjct: 919  GWVTCSSTDNTDLAFKKVGDGNPLKLWKASVEVEAPPSVVLNRVLRERHLWDEDFVQWKV 978

Query: 977  LEALMPGVELYHYVTDSMAPHPCRDFVVLRMWRSDLPRGGCLLVSQSLDPEQPVPESGVR 1036
            +E L    E+Y YV +SMAPHP RDFVVLR W++DLP+G C LVS S++ E+     GVR
Sbjct: 979  VETLDRQTEIYQYVLNSMAPHPSRDFVVLRTWKTDLPKGMCTLVSLSVEHEEAQLLGGVR 1038

Query: 1037 ALMLTSQYLMEPCGLGRSRLTHICRADLRGRSPDWYNKVFGHLCAMEVAKIRDSFPTLQA 1096
            A+++ SQYL+EPCG G+SRLTHICR DL+G SP+WY+K FGHLCA EVA+IR+SF  L A
Sbjct: 1039 AVVMDSQYLIEPCGSGKSRLTHICRIDLKGHSPEWYSKGFGHLCAAEVARIRNSFQPLIA 1098

Query: 1097 AGPETKL 1103
             GPETK+
Sbjct: 1099 EGPETKI 1105



 Score =  208 bits (529), Expect = 3e-53
 Identities = 158/467 (33%), Positives = 223/467 (47%), Gaps = 84/467 (17%)

Query: 27  EAEAKRACEWLQATGFPQYVQLFEEGSFPLDIGSVKKNHGFLDEDSLGALCRRLMTLNNC 86
           E EAK AC+WL+A GFPQY QL+E+  FP++I +VK +H FL++D +  LCRRL TLN C
Sbjct: 49  EIEAKEACDWLRAAGFPQYAQLYEDSQFPINIVAVKNDHDFLEKDLVEPLCRRLNTLNKC 108

Query: 87  ASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLL--------APPSP 138
           ASMKL+V+FQ K+ +DS+EE+ C IS+ W FQ+ S+ WS +     L        +P   
Sbjct: 109 ASMKLDVNFQRKKGDDSDEEDLC-ISNKWTFQRTSRRWSRVDDLYTLLPRGDRNGSPGGT 167

Query: 139 GLPATSSCESVLTELSATSLPVITVSLPPEPADLPLPGRA----PSSSDRPLLSPTQGQE 194
           G+  T+S ESVLT+LS   +  I             PG+     P   D PL+S +  Q 
Sbjct: 168 GMRNTTSSESVLTDLSEPEVCSIHSESSGGSDSRSQPGQCCTDNPVMLDAPLVSSSLPQP 227

Query: 195 ---------GPQDKAKKRHRNRSFLKHLESLRRKEKSGSQQAEPK------HSPATSEKV 239
                     P+++   R R +SFLK +E+LR K   G  +   +        P   ++ 
Sbjct: 228 PRDVLNHPFHPKNEKPTRARAKSFLKRMETLRGKGAHGRHKGSGRTGGLVISGPMLQQEP 287

Query: 240 SKASSFR---------------SCRGFLSAGFYRAKNWAATSAGGSGANT-----RKAWE 279
               + +               +CR  L      +   + +    SG +T     RK  E
Sbjct: 288 ESFKAMQCIQIPNGDLQNSPPPACRKGLPCSGKSSGESSPSEHSSSGVSTPCLKERKCHE 347

Query: 280 ------------------AWPVA--SFRHPQWTHRGDCLVHVPGDHKPGTFPRSLSIESL 319
                             A P A    R  ++  + + +VH+P DHKPGTFP++LSIESL
Sbjct: 348 ANKRGGMYLEDLDVLAGTALPDAGDQSRMHEFHSQENLVVHIPKDHKPGTFPKALSIESL 407

Query: 320 CPEDGHRLADWQPGR----RWGCEGRR-----GSCGSTGSHASTYDNLPELYPAEPVMVG 370
            P D     +W+ G     R    G R      SC    S  S YDN+P  +      + 
Sbjct: 408 SPTDSSNGVNWRTGSISLGREQVPGAREPRLMASC-HRASRVSIYDNVPGSH------LY 460

Query: 371 AEAEDEDDEESGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGD 417
           A   D  D E    + HLDDILQHV GLQ+ V+ WS+ + P+L   D
Sbjct: 461 ASTGDLLDLEKDDLFPHLDDILQHVNGLQEVVDDWSKDVLPELQTHD 507


>gi|16445031 StAR-related lipid transfer (START) domain containing 13
            isoform gamma [Homo sapiens]
          Length = 995

 Score =  683 bits (1762), Expect = 0.0
 Identities = 353/607 (58%), Positives = 452/607 (74%), Gaps = 20/607 (3%)

Query: 505  GEP---TFASSLSVE---EGHSISDTVASSSELDSSGNSMNEAEAAGPLAGLQASMPRER 558
            GEP   TF S   +    EG+S+S+   + S+++    S+NE+E  G          R+R
Sbjct: 401  GEPGLSTFPSPNQITLDFEGNSVSEGRTTPSDVERDVTSLNESEPPGV---------RDR 451

Query: 559  RDSGVGASLTRPCRKLRWHSFQNSHRPSLNSESLEINRQFAGQINLLHKGSLLRLTAFME 618
            RDSGVGASLTRP R+LRW+SFQ SH+P     S  I+ Q A Q++LL + SLLRLTA ME
Sbjct: 452  RDSGVGASLTRPNRRLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQRFSLLRLTAIME 511

Query: 619  KYTVPHKQGWVWSMPKFMRRNKTPDYRGQHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRS 678
            K+++ +K GW WS+PKFM+R K PDY+ + VFGVP ++HVQRTGQPLPQSIQQA+RYLRS
Sbjct: 512  KHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVHVQRTGQPLPQSIQQALRYLRS 571

Query: 679  QCLDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTS 738
             CLDQVG+FRKSGVKSRI  LRQMNE  P+NV YE QSAYDVAD++KQ+FRDLPEP+FT+
Sbjct: 572  NCLDQVGLFRKSGVKSRIHALRQMNENFPENVNYEDQSAYDVADMVKQFFRDLPEPLFTN 631

Query: 739  KLTTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSDIAS-AEENQMTAGN 797
            KL+ TFL IYQ + K+Q L A QAA LLL DENREVLQTLL FL+D+ +  EENQMT  N
Sbjct: 632  KLSETFLHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEENQMTPMN 691

Query: 798  LAVCLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPGPRDLSDNMAATQGLSHMISDCKKLF 857
            LAVCLAPS+FHLN+ KK+S SPR+  K+   G+P  +DL++N+AA QGL+HMI +C +LF
Sbjct: 692  LAVCLAPSLFHLNLLKKES-SPRVIQKKYATGKPDQKDLNENLAAAQGLAHMIMECDRLF 750

Query: 858  QVPQDMVLQLCSSYSAAELSPPGPALAEL-RQAQAAGVSLSLYMEENIQDLLRDAAERFK 916
            +VP ++V Q  +SY  AE+    P L EL  Q + +G +   Y+   IQ L ++A E+FK
Sbjct: 751  EVPHELVAQSRNSYVEAEIHV--PTLEELGTQLEESGATFHTYLNHLIQGLQKEAKEKFK 808

Query: 917  GWMSVPGPQHTELACRKAPDGHPLRLWKASTEVAAPPAVVLHRVLRERALWDEDLLRAQV 976
            GW++     +T+LA +K  DG+PL+LWKAS EV APP+VVL+RVLRER LWDED ++ +V
Sbjct: 809  GWVTCSSTDNTDLAFKKVGDGNPLKLWKASVEVEAPPSVVLNRVLRERHLWDEDFVQWKV 868

Query: 977  LEALMPGVELYHYVTDSMAPHPCRDFVVLRMWRSDLPRGGCLLVSQSLDPEQPVPESGVR 1036
            +E L    E+Y YV +SMAPHP RDFVVLR W++DLP+G C LVS S++ E+     GVR
Sbjct: 869  VETLDRQTEIYQYVLNSMAPHPSRDFVVLRTWKTDLPKGMCTLVSLSVEHEEAQLLGGVR 928

Query: 1037 ALMLTSQYLMEPCGLGRSRLTHICRADLRGRSPDWYNKVFGHLCAMEVAKIRDSFPTLQA 1096
            A+++ SQYL+EPCG G+SRLTHICR DL+G SP+WY+K FGHLCA EVA+IR+SF  L A
Sbjct: 929  AVVMDSQYLIEPCGSGKSRLTHICRIDLKGHSPEWYSKGFGHLCAAEVARIRNSFQPLIA 988

Query: 1097 AGPETKL 1103
             GPETK+
Sbjct: 989  EGPETKI 995



 Score =  127 bits (319), Expect = 6e-29
 Identities = 121/405 (29%), Positives = 175/405 (43%), Gaps = 84/405 (20%)

Query: 89  MKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLL--------APPSPGL 140
           MKL+V+FQ K+ +DS+EE+ C IS+ W FQ+ S+ WS +     L        +P   G+
Sbjct: 1   MKLDVNFQRKKGDDSDEEDLC-ISNKWTFQRTSRRWSRVDDLYTLLPRGDRNGSPGGTGM 59

Query: 141 PATSSCESVLTELSATSLPVITVSLPPEPADLPLPGRA----PSSSDRPLLSPTQGQEG- 195
             T+S ESVLT+LS   +  I             PG+     P   D PL+S +  Q   
Sbjct: 60  RNTTSSESVLTDLSEPEVCSIHSESSGGSDSRSQPGQCCTDNPVMLDAPLVSSSLPQPPR 119

Query: 196 --------PQDKAKKRHRNRSFLKHLESLRRKEKSGSQQAEPK------HSPATSEKVSK 241
                   P+++   R R +SFLK +E+LR K   G  +   +        P   ++   
Sbjct: 120 DVLNHPFHPKNEKPTRARAKSFLKRMETLRGKGAHGRHKGSGRTGGLVISGPMLQQEPES 179

Query: 242 ASSFR---------------SCRGFLSAGFYRAKNWAATSAGGSGANT-----RKAWEA- 280
             + +               +CR  L      +   + +    SG +T     RK  EA 
Sbjct: 180 FKAMQCIQIPNGDLQNSPPPACRKGLPCSGKSSGESSPSEHSSSGVSTPCLKERKCHEAN 239

Query: 281 -----------------WPVAS--FRHPQWTHRGDCLVHVPGDHKPGTFPRSLSIESLCP 321
                             P A    R  ++  + + +VH+P DHKPGTFP++LSIESL P
Sbjct: 240 KRGGMYLEDLDVLAGTALPDAGDQSRMHEFHSQENLVVHIPKDHKPGTFPKALSIESLSP 299

Query: 322 EDGHRLADWQPGR----RWGCEGRR-----GSCGSTGSHASTYDNLPELYPAEPVMVGAE 372
            D     +W+ G     R    G R      SC    S  S YDN+P  +      + A 
Sbjct: 300 TDSSNGVNWRTGSISLGREQVPGAREPRLMASC-HRASRVSIYDNVPGSH------LYAS 352

Query: 373 AEDEDDEESGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGD 417
             D  D E    + HLDDILQHV GLQ+ V+ WS+ + P+L   D
Sbjct: 353 TGDLLDLEKDDLFPHLDDILQHVNGLQEVVDDWSKDVLPELQTHD 397


>gi|41281898 StAR-related lipid transfer (START) domain containing 13
            isoform alpha [Homo sapiens]
          Length = 1113

 Score =  683 bits (1762), Expect = 0.0
 Identities = 353/607 (58%), Positives = 452/607 (74%), Gaps = 20/607 (3%)

Query: 505  GEP---TFASSLSVE---EGHSISDTVASSSELDSSGNSMNEAEAAGPLAGLQASMPRER 558
            GEP   TF S   +    EG+S+S+   + S+++    S+NE+E  G          R+R
Sbjct: 519  GEPGLSTFPSPNQITLDFEGNSVSEGRTTPSDVERDVTSLNESEPPGV---------RDR 569

Query: 559  RDSGVGASLTRPCRKLRWHSFQNSHRPSLNSESLEINRQFAGQINLLHKGSLLRLTAFME 618
            RDSGVGASLTRP R+LRW+SFQ SH+P     S  I+ Q A Q++LL + SLLRLTA ME
Sbjct: 570  RDSGVGASLTRPNRRLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQRFSLLRLTAIME 629

Query: 619  KYTVPHKQGWVWSMPKFMRRNKTPDYRGQHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRS 678
            K+++ +K GW WS+PKFM+R K PDY+ + VFGVP ++HVQRTGQPLPQSIQQA+RYLRS
Sbjct: 630  KHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVHVQRTGQPLPQSIQQALRYLRS 689

Query: 679  QCLDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTS 738
             CLDQVG+FRKSGVKSRI  LRQMNE  P+NV YE QSAYDVAD++KQ+FRDLPEP+FT+
Sbjct: 690  NCLDQVGLFRKSGVKSRIHALRQMNENFPENVNYEDQSAYDVADMVKQFFRDLPEPLFTN 749

Query: 739  KLTTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSDIAS-AEENQMTAGN 797
            KL+ TFL IYQ + K+Q L A QAA LLL DENREVLQTLL FL+D+ +  EENQMT  N
Sbjct: 750  KLSETFLHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEENQMTPMN 809

Query: 798  LAVCLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPGPRDLSDNMAATQGLSHMISDCKKLF 857
            LAVCLAPS+FHLN+ KK+S SPR+  K+   G+P  +DL++N+AA QGL+HMI +C +LF
Sbjct: 810  LAVCLAPSLFHLNLLKKES-SPRVIQKKYATGKPDQKDLNENLAAAQGLAHMIMECDRLF 868

Query: 858  QVPQDMVLQLCSSYSAAELSPPGPALAEL-RQAQAAGVSLSLYMEENIQDLLRDAAERFK 916
            +VP ++V Q  +SY  AE+    P L EL  Q + +G +   Y+   IQ L ++A E+FK
Sbjct: 869  EVPHELVAQSRNSYVEAEIHV--PTLEELGTQLEESGATFHTYLNHLIQGLQKEAKEKFK 926

Query: 917  GWMSVPGPQHTELACRKAPDGHPLRLWKASTEVAAPPAVVLHRVLRERALWDEDLLRAQV 976
            GW++     +T+LA +K  DG+PL+LWKAS EV APP+VVL+RVLRER LWDED ++ +V
Sbjct: 927  GWVTCSSTDNTDLAFKKVGDGNPLKLWKASVEVEAPPSVVLNRVLRERHLWDEDFVQWKV 986

Query: 977  LEALMPGVELYHYVTDSMAPHPCRDFVVLRMWRSDLPRGGCLLVSQSLDPEQPVPESGVR 1036
            +E L    E+Y YV +SMAPHP RDFVVLR W++DLP+G C LVS S++ E+     GVR
Sbjct: 987  VETLDRQTEIYQYVLNSMAPHPSRDFVVLRTWKTDLPKGMCTLVSLSVEHEEAQLLGGVR 1046

Query: 1037 ALMLTSQYLMEPCGLGRSRLTHICRADLRGRSPDWYNKVFGHLCAMEVAKIRDSFPTLQA 1096
            A+++ SQYL+EPCG G+SRLTHICR DL+G SP+WY+K FGHLCA EVA+IR+SF  L A
Sbjct: 1047 AVVMDSQYLIEPCGSGKSRLTHICRIDLKGHSPEWYSKGFGHLCAAEVARIRNSFQPLIA 1106

Query: 1097 AGPETKL 1103
             GPETK+
Sbjct: 1107 EGPETKI 1113



 Score =  209 bits (532), Expect = 1e-53
 Identities = 160/474 (33%), Positives = 225/474 (47%), Gaps = 84/474 (17%)

Query: 20  LQVKKNAEAEAKRACEWLQATGFPQYVQLFEEGSFPLDIGSVKKNHGFLDEDSLGALCRR 79
           L  K   E EAK AC+WL+A GFPQY QL+E+  FP++I +VK +H FL++D +  LCRR
Sbjct: 50  LVTKIQQEIEAKEACDWLRAAGFPQYAQLYEDSQFPINIVAVKNDHDFLEKDLVEPLCRR 109

Query: 80  LMTLNNCASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLL------ 133
           L TLN CASMKL+V+FQ K+ +DS+EE+ C IS+ W FQ+ S+ WS +     L      
Sbjct: 110 LNTLNKCASMKLDVNFQRKKGDDSDEEDLC-ISNKWTFQRTSRRWSRVDDLYTLLPRGDR 168

Query: 134 --APPSPGLPATSSCESVLTELSATSLPVITVSLPPEPADLPLPGRA----PSSSDRPLL 187
             +P   G+  T+S ESVLT+LS   +  I             PG+     P   D PL+
Sbjct: 169 NGSPGGTGMRNTTSSESVLTDLSEPEVCSIHSESSGGSDSRSQPGQCCTDNPVMLDAPLV 228

Query: 188 SPTQGQE---------GPQDKAKKRHRNRSFLKHLESLRRKEKSGSQQAEPK------HS 232
           S +  Q           P+++   R R +SFLK +E+LR K   G  +   +        
Sbjct: 229 SSSLPQPPRDVLNHPFHPKNEKPTRARAKSFLKRMETLRGKGAHGRHKGSGRTGGLVISG 288

Query: 233 PATSEKVSKASSFR---------------SCRGFLSAGFYRAKNWAATSAGGSGANT--- 274
           P   ++     + +               +CR  L      +   + +    SG +T   
Sbjct: 289 PMLQQEPESFKAMQCIQIPNGDLQNSPPPACRKGLPCSGKSSGESSPSEHSSSGVSTPCL 348

Query: 275 --RKAWE------------------AWPVA--SFRHPQWTHRGDCLVHVPGDHKPGTFPR 312
             RK  E                  A P A    R  ++  + + +VH+P DHKPGTFP+
Sbjct: 349 KERKCHEANKRGGMYLEDLDVLAGTALPDAGDQSRMHEFHSQENLVVHIPKDHKPGTFPK 408

Query: 313 SLSIESLCPEDGHRLADWQPGR----RWGCEGRR-----GSCGSTGSHASTYDNLPELYP 363
           +LSIESL P D     +W+ G     R    G R      SC    S  S YDN+P  + 
Sbjct: 409 ALSIESLSPTDSSNGVNWRTGSISLGREQVPGAREPRLMASC-HRASRVSIYDNVPGSH- 466

Query: 364 AEPVMVGAEAEDEDDEESGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGD 417
                + A   D  D E    + HLDDILQHV GLQ+ V+ WS+ + P+L   D
Sbjct: 467 -----LYASTGDLLDLEKDDLFPHLDDILQHVNGLQEVVDDWSKDVLPELQTHD 515


>gi|33188433 deleted in liver cancer 1 isoform 1 [Homo sapiens]
          Length = 1528

 Score =  653 bits (1684), Expect = 0.0
 Identities = 335/577 (58%), Positives = 430/577 (74%), Gaps = 15/577 (2%)

Query: 529  SELDSSGNSMNEAEAAGPLAGLQASMPRERRDSGVGASLTRPCR-KLRWHSFQNSHRPSL 587
            S+LDS+GNS+NE E    +         ERRDSGVGASLTR  R +LRWHSFQ+SHRPSL
Sbjct: 962  SDLDSTGNSLNEPEEPSEIP--------ERRDSGVGASLTRSNRHRLRWHSFQSSHRPSL 1013

Query: 588  NSESLEINRQFAGQINLLHKGSLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQ 647
            NS SL+IN Q   Q+NLL K SLL+LTA +EKYT  +K G+ W++PKFM+R K PDY+ +
Sbjct: 1014 NSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDR 1073

Query: 648  HVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSP 707
             VFGVP  ++VQRTGQPLPQSIQQAMRYLR+ CLDQVG+FRKSGVKSRIQ LRQMNE + 
Sbjct: 1074 SVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI 1133

Query: 708  DNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLL 767
            D V YEGQSAYDVAD+LKQYFRDLPEP+ T+KL+ TFLQIYQ +PKDQ L A +AA +LL
Sbjct: 1134 DCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLL 1193

Query: 768  PDENREVLQTLLYFLSDI-ASAEENQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRS 826
            PDENREVLQTLLYFLSD+ A+ +ENQMT  NLAVCLAPS+FHLN  K+++ SPR+  ++ 
Sbjct: 1194 PDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQ 1253

Query: 827  LIGRPGPRDLSDNMAATQGLSHMISDCKKLFQVPQDMVLQLCSSYSAAELSP-PGPALAE 885
             +G+P  +DL++N+AATQGL+HMI++CKKLFQVP++M  +  +SY+  EL P    AL  
Sbjct: 1254 SLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEM-SRCRNSYTEQELKPLTLEALGH 1312

Query: 886  LRQAQAAGVSLSLYMEENIQDLLRDAAERFKGWMSVPGPQHTELACRKAPDGHPLRLWKA 945
            L    +A      ++++ +  L ++  E+FKGW+S    +  EL+ +K  +G PLRLW++
Sbjct: 1313 LGNDDSA--DYQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRS 1370

Query: 946  STEVAAPPAVVLHRVLRERALWDEDLLRAQVLEALMPGVELYHYVTDSMAPHPCRDFVVL 1005
              EV A P  +L R+L+E+ LWD DLL ++V+E L    E+Y YV +SMAPHP RD+VVL
Sbjct: 1371 VIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVL 1430

Query: 1006 RMWRSDLPRGGCLLVSQSLDPEQPVPESGVRALMLTSQYLMEPCGLGRSRLTHICRADLR 1065
            R WR++LP+G C L+  S+D ++  P  GVR  +L S+YL+EPCG G+S+LT++CR DLR
Sbjct: 1431 RTWRTNLPKGACALLLTSVDHDR-APVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLR 1489

Query: 1066 GRSPDWYNKVFGHLCAMEVAKIRDSFPTLQAAGPETK 1102
            G  P+WY K FGHLCA EV KIRDSF        +TK
Sbjct: 1490 GHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTK 1526



 Score =  149 bits (375), Expect = 2e-35
 Identities = 97/246 (39%), Positives = 128/246 (52%), Gaps = 43/246 (17%)

Query: 23  KKNAEAEAKRACEWLQATGFPQYVQLFEEGSFPLDIGSVKKNHGFLDEDSLGALCRRLMT 82
           K+ AE EAK AC+WL+ATGFPQY QL+E+  FP+DI  VK+ H FLD D++ ALCRRL T
Sbjct: 446 KEKAEIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNT 505

Query: 83  LNNCASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLLAP------- 135
           LN CA MKLE+    K+++DS+E+E C IS  W FQ++SK WS +   D+ +P       
Sbjct: 506 LNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPG 565

Query: 136 ----------PSPG-----LPATSSCESVLTELSATSLPVITVSLPPEPADLP------- 173
                     PSPG     L       SV +  S  SLP  + + P E A  P       
Sbjct: 566 SPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLP--SHAPPSEDAATPRTNSVIS 623

Query: 174 ------LPGRAPS----SSDRPLLSPTQGQEGPQDKAKKRHRNRSFLKHLESLRRKEKSG 223
                 L G   S     S + L S +   +G +  AK   + RS LK +ESL+ K    
Sbjct: 624 VCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKS--KTRSLLKRMESLKLKSSHH 681

Query: 224 SQQAEP 229
           S+   P
Sbjct: 682 SKHKAP 687



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 59/217 (27%), Positives = 85/217 (39%), Gaps = 45/217 (20%)

Query: 222 SGSQQAEPKHSPATSEKVSKASSFRSCR---GFLSAGFYRAKNWAATSAGGSGANTRKAW 278
           S S Q+E   + +T   V++  S  +C    G    GF         +        R+++
Sbjct: 742 SSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESY 801

Query: 279 EAWPVASFRHPQWTHRGDCLVHVPGDHKPGTFPRSLSIESLCPEDGHRLADWQPG----- 333
                            D + ++P DHKPGTFP++L+  S  P   +   +W+ G     
Sbjct: 802 PE---------------DTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGP 846

Query: 334 -----RRWGCEG------RRGSCGSTGSHASTYDNLPE--LYPAEPVMVGAEAEDEDDEE 380
                RR           RR S  S  S  S YDN+P   LY +   +   E ED     
Sbjct: 847 GHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENED----- 901

Query: 381 SGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGD 417
               +  LDDIL HV G+Q+ V  WS   + D G  D
Sbjct: 902 ---IFPELDDILYHVKGMQRIVNQWSE-KFSDEGDSD 934


>gi|33188437 deleted in liver cancer 1 isoform 2 [Homo sapiens]
          Length = 1091

 Score =  653 bits (1684), Expect = 0.0
 Identities = 335/577 (58%), Positives = 430/577 (74%), Gaps = 15/577 (2%)

Query: 529  SELDSSGNSMNEAEAAGPLAGLQASMPRERRDSGVGASLTRPCR-KLRWHSFQNSHRPSL 587
            S+LDS+GNS+NE E    +         ERRDSGVGASLTR  R +LRWHSFQ+SHRPSL
Sbjct: 525  SDLDSTGNSLNEPEEPSEIP--------ERRDSGVGASLTRSNRHRLRWHSFQSSHRPSL 576

Query: 588  NSESLEINRQFAGQINLLHKGSLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQ 647
            NS SL+IN Q   Q+NLL K SLL+LTA +EKYT  +K G+ W++PKFM+R K PDY+ +
Sbjct: 577  NSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDR 636

Query: 648  HVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSP 707
             VFGVP  ++VQRTGQPLPQSIQQAMRYLR+ CLDQVG+FRKSGVKSRIQ LRQMNE + 
Sbjct: 637  SVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAI 696

Query: 708  DNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLL 767
            D V YEGQSAYDVAD+LKQYFRDLPEP+ T+KL+ TFLQIYQ +PKDQ L A +AA +LL
Sbjct: 697  DCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLL 756

Query: 768  PDENREVLQTLLYFLSDI-ASAEENQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRS 826
            PDENREVLQTLLYFLSD+ A+ +ENQMT  NLAVCLAPS+FHLN  K+++ SPR+  ++ 
Sbjct: 757  PDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQ 816

Query: 827  LIGRPGPRDLSDNMAATQGLSHMISDCKKLFQVPQDMVLQLCSSYSAAELSP-PGPALAE 885
             +G+P  +DL++N+AATQGL+HMI++CKKLFQVP++M  +  +SY+  EL P    AL  
Sbjct: 817  SLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEM-SRCRNSYTEQELKPLTLEALGH 875

Query: 886  LRQAQAAGVSLSLYMEENIQDLLRDAAERFKGWMSVPGPQHTELACRKAPDGHPLRLWKA 945
            L    +A      ++++ +  L ++  E+FKGW+S    +  EL+ +K  +G PLRLW++
Sbjct: 876  LGNDDSA--DYQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRS 933

Query: 946  STEVAAPPAVVLHRVLRERALWDEDLLRAQVLEALMPGVELYHYVTDSMAPHPCRDFVVL 1005
              EV A P  +L R+L+E+ LWD DLL ++V+E L    E+Y YV +SMAPHP RD+VVL
Sbjct: 934  VIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVL 993

Query: 1006 RMWRSDLPRGGCLLVSQSLDPEQPVPESGVRALMLTSQYLMEPCGLGRSRLTHICRADLR 1065
            R WR++LP+G C L+  S+D ++  P  GVR  +L S+YL+EPCG G+S+LT++CR DLR
Sbjct: 994  RTWRTNLPKGACALLLTSVDHDR-APVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLR 1052

Query: 1066 GRSPDWYNKVFGHLCAMEVAKIRDSFPTLQAAGPETK 1102
            G  P+WY K FGHLCA EV KIRDSF        +TK
Sbjct: 1053 GHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTK 1089



 Score =  144 bits (362), Expect = 6e-34
 Identities = 94/242 (38%), Positives = 125/242 (51%), Gaps = 43/242 (17%)

Query: 27  EAEAKRACEWLQATGFPQYVQLFEEGSFPLDIGSVKKNHGFLDEDSLGALCRRLMTLNNC 86
           + EAK AC+WL+ATGFPQY QL+E+  FP+DI  VK+ H FLD D++ ALCRRL TLN C
Sbjct: 13  QIEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNTLNKC 72

Query: 87  ASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLLAP----------- 135
           A MKLE+    K+++DS+E+E C IS  W FQ++SK WS +   D+ +P           
Sbjct: 73  AVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPGSPDD 132

Query: 136 ------PSPG-----LPATSSCESVLTELSATSLPVITVSLPPEPADLP----------- 173
                 PSPG     L       SV +  S  SLP  + + P E A  P           
Sbjct: 133 SHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLP--SHAPPSEDAATPRTNSVISVCSS 190

Query: 174 --LPGRAPS----SSDRPLLSPTQGQEGPQDKAKKRHRNRSFLKHLESLRRKEKSGSQQA 227
             L G   S     S + L S +   +G +  AK   + RS LK +ESL+ K    S+  
Sbjct: 191 SNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKS--KTRSLLKRMESLKLKSSHHSKHK 248

Query: 228 EP 229
            P
Sbjct: 249 AP 250



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 59/217 (27%), Positives = 85/217 (39%), Gaps = 45/217 (20%)

Query: 222 SGSQQAEPKHSPATSEKVSKASSFRSCR---GFLSAGFYRAKNWAATSAGGSGANTRKAW 278
           S S Q+E   + +T   V++  S  +C    G    GF         +        R+++
Sbjct: 305 SSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESY 364

Query: 279 EAWPVASFRHPQWTHRGDCLVHVPGDHKPGTFPRSLSIESLCPEDGHRLADWQPG----- 333
                            D + ++P DHKPGTFP++L+  S  P   +   +W+ G     
Sbjct: 365 PE---------------DTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGP 409

Query: 334 -----RRWGCEG------RRGSCGSTGSHASTYDNLPE--LYPAEPVMVGAEAEDEDDEE 380
                RR           RR S  S  S  S YDN+P   LY +   +   E ED     
Sbjct: 410 GHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENED----- 464

Query: 381 SGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGD 417
               +  LDDIL HV G+Q+ V  WS   + D G  D
Sbjct: 465 ---IFPELDDILYHVKGMQRIVNQWSE-KFSDEGDSD 497


>gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]
          Length = 771

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 63/211 (29%), Positives = 98/211 (46%), Gaps = 24/211 (11%)

Query: 665 LPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLL 724
           +P+ +    ++L    L  VGIFR    K R++ LR+  +   D    E  S +DVA LL
Sbjct: 207 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 266

Query: 725 KQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSD 784
           K++ RD+P+P+ T +L T F+    L P++Q L   Q    LLP  N + L  LL FLS 
Sbjct: 267 KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 325

Query: 785 IASAEE------------NQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPG 832
           +A   +            N+MT+ NLA    P++ H   S     S +  ++        
Sbjct: 326 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSAR-------- 377

Query: 833 PRDLSDNMAATQGLSHMISDCKKLFQVPQDM 863
                ++ A    +  MI + + LF VP D+
Sbjct: 378 ---AEESTAIIAVVQKMIENYEALFMVPPDL 405


>gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo
           sapiens]
          Length = 765

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 63/211 (29%), Positives = 98/211 (46%), Gaps = 24/211 (11%)

Query: 665 LPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLL 724
           +P+ +    ++L    L  VGIFR    K R++ LR+  +   D    E  S +DVA LL
Sbjct: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 469

Query: 725 KQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSD 784
           K++ RD+P+P+ T +L T F+    L P++Q L   Q    LLP  N + L  LL FLS 
Sbjct: 470 KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 528

Query: 785 IASAEE------------NQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPG 832
           +A   +            N+MT+ NLA    P++ H   S     S +  ++        
Sbjct: 529 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSAR-------- 580

Query: 833 PRDLSDNMAATQGLSHMISDCKKLFQVPQDM 863
                ++ A    +  MI + + LF VP D+
Sbjct: 581 ---AEESTAIIAVVQKMIENYEALFMVPPDL 608


>gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo
           sapiens]
          Length = 974

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 63/211 (29%), Positives = 98/211 (46%), Gaps = 24/211 (11%)

Query: 665 LPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLL 724
           +P+ +    ++L    L  VGIFR    K R++ LR+  +   D    E  S +DVA LL
Sbjct: 410 VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALL 469

Query: 725 KQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSD 784
           K++ RD+P+P+ T +L T F+    L P++Q L   Q    LLP  N + L  LL FLS 
Sbjct: 470 KEFLRDMPDPLLTRELYTAFINTLLLEPEEQ-LGTLQLLIYLLPPCNCDTLHRLLQFLSI 528

Query: 785 IASAEE------------NQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPG 832
           +A   +            N+MT+ NLA    P++ H   S     S +  ++        
Sbjct: 529 VARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSAR-------- 580

Query: 833 PRDLSDNMAATQGLSHMISDCKKLFQVPQDM 863
                ++ A    +  MI + + LF VP D+
Sbjct: 581 ---AEESTAIIAVVQKMIENYEALFMVPPDL 608


>gi|39932589 Rho GTPase activating protein 18 [Homo sapiens]
          Length = 663

 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 50/149 (33%), Positives = 78/149 (52%), Gaps = 3/149 (2%)

Query: 662 GQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETS--PDNVCYEGQSAYD 719
           G  +P   Q+ +  +  + L+  G+ R  G   RI+NL Q  E         +E    +D
Sbjct: 339 GMRIPLIFQKLISRIEERGLETEGLLRIPGAAIRIKNLCQELEAKFYEGTFNWESVKQHD 398

Query: 720 VADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLL 779
            A LLK + R+LP+P+ + +    F  +  L  K Q L A     +LLPD NR+ L+ LL
Sbjct: 399 AASLLKLFIRELPQPLLSVEYLKAFQAVQNLPTKKQQLQALNLLVILLPDANRDTLKALL 458

Query: 780 YFLSD-IASAEENQMTAGNLAVCLAPSIF 807
            FL   I + E+N+MT  N+A+ +AP++F
Sbjct: 459 EFLQRVIDNKEKNKMTVMNVAMVMAPNLF 487


>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
          Length = 2022

 Score = 80.9 bits (198), Expect = 6e-15
 Identities = 47/143 (32%), Positives = 78/143 (54%), Gaps = 1/143 (0%)

Query: 665  LPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLL 724
            +P  +++ + ++    L   G++RKSG  +R + LRQ  +T P  V  E    + +  +L
Sbjct: 1712 VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAITGVL 1771

Query: 725  KQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSD 784
            KQ+ R+LPEP+ T      FL+  +L  K + LAA  A    LP+ N   L+ L++ L  
Sbjct: 1772 KQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVK 1831

Query: 785  IASAEE-NQMTAGNLAVCLAPSI 806
            +A  E+ N+M+ G LA+  AP +
Sbjct: 1832 VALLEDVNRMSPGALAIIFAPCL 1854


>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
          Length = 2157

 Score = 80.9 bits (198), Expect = 6e-15
 Identities = 47/143 (32%), Positives = 78/143 (54%), Gaps = 1/143 (0%)

Query: 665  LPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLL 724
            +P  +++ + ++    L   G++RKSG  +R + LRQ  +T P  V  E    + +  +L
Sbjct: 1712 VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAITGVL 1771

Query: 725  KQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSD 784
            KQ+ R+LPEP+ T      FL+  +L  K + LAA  A    LP+ N   L+ L++ L  
Sbjct: 1772 KQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVK 1831

Query: 785  IASAEE-NQMTAGNLAVCLAPSI 806
            +A  E+ N+M+ G LA+  AP +
Sbjct: 1832 VALLEDVNRMSPGALAIIFAPCL 1854


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 49/159 (30%), Positives = 82/159 (51%), Gaps = 1/159 (0%)

Query: 649 VFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSPD 708
           V+GV    H+Q  G+ +   I+  +  L S+ + + G+FR +   S ++ L+Q   + P 
Sbjct: 273 VYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPH 332

Query: 709 NVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLLP 768
           ++       + VA  LK Y R+LPEP+ T  L   +++   L      L A Q     LP
Sbjct: 333 SLEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCSRLP 392

Query: 769 DENREVLQTLLYFLSDIASAEE-NQMTAGNLAVCLAPSI 806
            EN   L+ L+ FL+ +A  +E N+MT  N+A+ L P++
Sbjct: 393 PENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNL 431



 Score = 35.4 bits (80), Expect = 0.30
 Identities = 33/103 (32%), Positives = 51/103 (49%), Gaps = 13/103 (12%)

Query: 402 VELWSRAMYPDLGPGDEEEEEATSSVEIATVEVKCQAEALSQM-EVPAHGE-----SPAW 455
           + L    ++P    GD+ + +A S   +++++V    EAL Q  +    G+     S  +
Sbjct: 425 IVLGPNLLWPPEKEGDQAQLDAAS---VSSIQVVGVVEALIQSADTLFPGDINFNVSGLF 481

Query: 456 AQAEVQPAV---LAPAQAPAEAEPV-AQEEAEAPAPAPAPAPA 494
           +   +Q  V   LA  + P+ A P  A   A APAPAPAPAPA
Sbjct: 482 SAVTLQDTVSDRLASEELPSTAVPTPATTPAPAPAPAPAPAPA 524



 Score = 31.2 bits (69), Expect = 5.7
 Identities = 23/62 (37%), Positives = 28/62 (45%), Gaps = 7/62 (11%)

Query: 431 TVEVKCQAEALSQMEVPAHGESPAWAQAEVQPAVLAPAQAPAEAEPVAQEEAEAPAPAPA 490
           TV  +  +E L    VP    +PA A A       APA APA A    +E  E+  P P 
Sbjct: 489 TVSDRLASEELPSTAVPTPATTPAPAPAP------APAPAPALASAATKERTESEVP-PR 541

Query: 491 PA 492
           PA
Sbjct: 542 PA 543


>gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]
          Length = 946

 Score = 77.4 bits (189), Expect = 7e-14
 Identities = 55/174 (31%), Positives = 84/174 (48%), Gaps = 5/174 (2%)

Query: 637 RRNKTPDYRGQHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRI 696
           R+ +      Q +FG      +Q +GQP+P  ++  +R++    L   GIFR SG + R+
Sbjct: 492 RQPRPSSQYNQRLFGGDMEKFIQSSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQLRV 551

Query: 697 QNLRQMNETSPDNVCYEGQSAYD---VADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPK 753
             +R   E   D +  EG +A+D   VA +LK YFR L  P+F   L    L   +L   
Sbjct: 552 SEIRDAFERGEDPL-VEGCTAHDLDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEAT 610

Query: 754 DQWLAAAQAATLLLPDENREVLQTLLYFLSDIAS-AEENQMTAGNLAVCLAPSI 806
            + +         LP     VL+ L  FL+ +A  ++EN M   NLAVC  P++
Sbjct: 611 AERVEHVSRLLWRLPAPVLVVLRYLFTFLNHLAQYSDENMMDPYNLAVCFGPTL 664


>gi|40255080 hypothetical protein LOC158763 [Homo sapiens]
          Length = 547

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 64/234 (27%), Positives = 110/234 (47%), Gaps = 25/234 (10%)

Query: 646 GQHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNET 705
           GQ + G    + +    + +PQ ++   +++    L  VGIF       R++ LR+  + 
Sbjct: 216 GQRLLGSKRKMSLNPIAKQIPQVVEACCQFIEKHGLSAVGIFTLEYSVQRVRQLREEFDQ 275

Query: 706 SPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATL 765
             D V  + Q+ +DVA LLK++FRD+ + +    L  +FL    L P+DQ L+A Q    
Sbjct: 276 GLDVVLDDNQNVHDVAALLKEFFRDMKDSLLPDDLYMSFLLTATLKPQDQ-LSALQLLVY 334

Query: 766 LLPDENREVLQTLLYFLSDIASAEE------------NQMTAGNLAVCLAPSIFHLNVSK 813
           L+P  + + L+ LL  L  I    E            N+MT+ NLA+     +F   + K
Sbjct: 335 LMPPCHSDTLERLLKALHKITENCEDSIGIDGQLVPGNRMTSTNLAL-----VFGSALLK 389

Query: 814 KDSPSPRIKSKRSLIGRPGPRDLSDNMAATQGLSHMISDCKKLFQVPQDMVLQL 867
           K     R +S+++ +G      +   +A+   +  MI +   LFQVP  +  Q+
Sbjct: 390 KGKFGKR-ESRKTKLG------IDHYVASVNVVRAMIDNWDVLFQVPPHIQRQV 436


>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
            sapiens]
          Length = 1499

 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 69/297 (23%), Positives = 140/297 (47%), Gaps = 20/297 (6%)

Query: 537  SMNEAEAAGPLAGLQASMPRERRDSGVGASL--------TRPCRKLRWHSFQNSHRPSLN 588
            ++N+A++ G   G  + M     + G   S+        TR  R  R+ S++ S     +
Sbjct: 1121 NINKAQSNGSGNGSDSEMDTSSLERGRKVSIVSKPVLYRTRCTRLGRFASYRTSFSVGSD 1180

Query: 589  SESLEINRQFAGQINLLHKGSLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNK-------T 641
             E   I ++   Q +  +KG    +    E    P ++  + S+ +  ++ K       T
Sbjct: 1181 DELGPIRKKEEDQASQGYKGDNAVIP--YETDEDPRRRNILRSLRRNTKKPKPKPRPSIT 1238

Query: 642  PDYRGQHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNL-R 700
                  + FGVP L  V    +P+P  I++ + Y+ +  L   GI+R SG KS +++L R
Sbjct: 1239 KATWESNYFGVP-LTTVVTPEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQR 1297

Query: 701  QMNETSPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAA 760
            Q ++    ++  +  +   VA  +K +F +LP+P+    +    ++ +++  ++Q L A 
Sbjct: 1298 QFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHAL 1357

Query: 761  QAATLLLPDENREVLQTLLYFLSDIA-SAEENQMTAGNLAVCLAPSIFHLNVSKKDS 816
            +      P EN EV + ++  L+ ++ + + N MT+ NL++C  P++   + S  D+
Sbjct: 1358 KEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFSTMDA 1414


>gi|59710113 Rho GTPase activating protein 28 isoform a [Homo
           sapiens]
          Length = 570

 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 54/210 (25%), Positives = 103/210 (49%), Gaps = 23/210 (10%)

Query: 609 SLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQH--VFGVPPLIHV-----QRT 661
           SL+ LTAF + + +             ++RNKT   +G+   +FGVP  + +     +  
Sbjct: 188 SLIELTAFFDAFGIQ------------LKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDP 235

Query: 662 GQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNET--SPDNVCYEGQSAYD 719
           G  +P  +Q+    +    L+  GIFR SG  ++++  R+  +   + D   ++     +
Sbjct: 236 GVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHRE 295

Query: 720 VADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQ-WLAAAQAATLLLPDENREVLQTL 778
            A +LK +FR+LP  +F  +    F+ + +  P  +    A     + LPD NR+  Q L
Sbjct: 296 AAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQAL 355

Query: 779 LYFLSD-IASAEENQMTAGNLAVCLAPSIF 807
           + F +  IA+  +N+M+  N++  +AP++F
Sbjct: 356 MTFFNKVIANESKNRMSLWNISTVMAPNLF 385


>gi|59710111 Rho GTPase activating protein 28 isoform b [Homo
           sapiens]
          Length = 563

 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 54/210 (25%), Positives = 103/210 (49%), Gaps = 23/210 (10%)

Query: 609 SLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQH--VFGVPPLIHV-----QRT 661
           SL+ LTAF + + +             ++RNKT   +G+   +FGVP  + +     +  
Sbjct: 188 SLIELTAFFDAFGIQ------------LKRNKTEKVKGRDNGIFGVPLTVLLDGDRKKDP 235

Query: 662 GQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNET--SPDNVCYEGQSAYD 719
           G  +P  +Q+    +    L+  GIFR SG  ++++  R+  +   + D   ++     +
Sbjct: 236 GVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDKMCHRE 295

Query: 720 VADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQ-WLAAAQAATLLLPDENREVLQTL 778
            A +LK +FR+LP  +F  +    F+ + +  P  +    A     + LPD NR+  Q L
Sbjct: 296 AAVMLKAFFRELPTSLFPVEYIPAFISLMERGPHVKVQFQALHLMVMALPDANRDAAQAL 355

Query: 779 LYFLSD-IASAEENQMTAGNLAVCLAPSIF 807
           + F +  IA+  +N+M+  N++  +AP++F
Sbjct: 356 MTFFNKVIANESKNRMSLWNISTVMAPNLF 385


>gi|239757488 PREDICTED: chromosome 20 open reading frame 95 [Homo
           sapiens]
          Length = 622

 Score = 73.9 bits (180), Expect = 8e-13
 Identities = 52/182 (28%), Positives = 89/182 (48%), Gaps = 10/182 (5%)

Query: 636 MRRNKTPDYRGQH--VFGVP--PLIHVQRTGQP---LPQSIQQAMRYLRSQCLDQVGIFR 688
           ++R+K   ++     +FGVP   L+       P   +P  +Q  +  L  + LD  GI R
Sbjct: 252 LKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILR 311

Query: 689 KSGVKSRIQNLRQMNETSPDNVCYEGQSAY--DVADLLKQYFRDLPEPIFTSKLTTTFLQ 746
             G ++R++ L Q  E       +     +  D +DLLK++ R LP P+ T++    F  
Sbjct: 312 VPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAV 371

Query: 747 IYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSDIASAEE-NQMTAGNLAVCLAPS 805
           +  +    Q L       L+LP+ NR  L+ LL FL  + + E+ N+MT  N++  +AP+
Sbjct: 372 VPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPN 431

Query: 806 IF 807
           +F
Sbjct: 432 LF 433


>gi|239752003 PREDICTED: chromosome 20 open reading frame 95 [Homo
           sapiens]
          Length = 622

 Score = 73.9 bits (180), Expect = 8e-13
 Identities = 52/182 (28%), Positives = 89/182 (48%), Gaps = 10/182 (5%)

Query: 636 MRRNKTPDYRGQH--VFGVP--PLIHVQRTGQP---LPQSIQQAMRYLRSQCLDQVGIFR 688
           ++R+K   ++     +FGVP   L+       P   +P  +Q  +  L  + LD  GI R
Sbjct: 252 LKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILR 311

Query: 689 KSGVKSRIQNLRQMNETSPDNVCYEGQSAY--DVADLLKQYFRDLPEPIFTSKLTTTFLQ 746
             G ++R++ L Q  E       +     +  D +DLLK++ R LP P+ T++    F  
Sbjct: 312 VPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAV 371

Query: 747 IYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSDIASAEE-NQMTAGNLAVCLAPS 805
           +  +    Q L       L+LP+ NR  L+ LL FL  + + E+ N+MT  N++  +AP+
Sbjct: 372 VPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPN 431

Query: 806 IF 807
           +F
Sbjct: 432 LF 433


>gi|239746488 PREDICTED: Rho GTPase-activating protein 18-like [Homo
           sapiens]
          Length = 622

 Score = 73.9 bits (180), Expect = 8e-13
 Identities = 52/182 (28%), Positives = 89/182 (48%), Gaps = 10/182 (5%)

Query: 636 MRRNKTPDYRGQH--VFGVP--PLIHVQRTGQP---LPQSIQQAMRYLRSQCLDQVGIFR 688
           ++R+K   ++     +FGVP   L+       P   +P  +Q  +  L  + LD  GI R
Sbjct: 252 LKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILR 311

Query: 689 KSGVKSRIQNLRQMNETSPDNVCYEGQSAY--DVADLLKQYFRDLPEPIFTSKLTTTFLQ 746
             G ++R++ L Q  E       +     +  D +DLLK++ R LP P+ T++    F  
Sbjct: 312 VPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAV 371

Query: 747 IYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSDIASAEE-NQMTAGNLAVCLAPS 805
           +  +    Q L       L+LP+ NR  L+ LL FL  + + E+ N+MT  N++  +AP+
Sbjct: 372 VPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPN 431

Query: 806 IF 807
           +F
Sbjct: 432 LF 433


>gi|156119615 myosin IXA [Homo sapiens]
          Length = 2548

 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 47/158 (29%), Positives = 83/158 (52%), Gaps = 2/158 (1%)

Query: 650  FGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSPDN 709
            FGV  L  +    + +P  +++ + Y+    L   GI+RKSG  ++I+ LRQ  +T  ++
Sbjct: 2061 FGVE-LSRLTSEDRTVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDAES 2119

Query: 710  VCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLLPD 769
            V  +  + + +A + KQ+ RDLP P+ T +L   FL+   L  + + +    +    L  
Sbjct: 2120 VNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVIDQLSR 2179

Query: 770  ENREVLQTLLYFLSDIASAEE-NQMTAGNLAVCLAPSI 806
             +   L+ L++ L  IA  E+ N+M+A  LA+  AP I
Sbjct: 2180 THLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCI 2217


>gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo
           sapiens]
          Length = 890

 Score = 71.2 bits (173), Expect = 5e-12
 Identities = 56/179 (31%), Positives = 88/179 (49%), Gaps = 9/179 (5%)

Query: 634 KFMRRNKTPDYRGQHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVK 693
           K  ++ K      + VFG     H+Q +GQ +PQ ++    ++    +   GI+R SGV 
Sbjct: 2   KSRQKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVD-GIYRLSGVS 60

Query: 694 SRIQNLRQM--NETSPD---NVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIY 748
           S IQ LRQ   +E  PD   +V    Q  + V+ L K YFR+LP+P+ T +L   F +  
Sbjct: 61  SNIQKLRQEFESERKPDLRRDVYL--QDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAV 118

Query: 749 QLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSDIAS-AEENQMTAGNLAVCLAPSI 806
            +  + + L         LP  N   L+ L+  L  +AS + +  M A NLA+  AP++
Sbjct: 119 GVQLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNL 177


>gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo
           sapiens]
          Length = 1101

 Score = 71.2 bits (173), Expect = 5e-12
 Identities = 56/179 (31%), Positives = 88/179 (49%), Gaps = 9/179 (5%)

Query: 634 KFMRRNKTPDYRGQHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVK 693
           K  ++ K      + VFG     H+Q +GQ +PQ ++    ++    +   GI+R SGV 
Sbjct: 2   KSRQKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVD-GIYRLSGVS 60

Query: 694 SRIQNLRQM--NETSPD---NVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIY 748
           S IQ LRQ   +E  PD   +V    Q  + V+ L K YFR+LP+P+ T +L   F +  
Sbjct: 61  SNIQKLRQEFESERKPDLRRDVYL--QDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAV 118

Query: 749 QLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSDIAS-AEENQMTAGNLAVCLAPSI 806
            +  + + L         LP  N   L+ L+  L  +AS + +  M A NLA+  AP++
Sbjct: 119 GVQLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNL 177


>gi|7661858 Rho GTPase activating protein 11A isoform 1 [Homo
           sapiens]
          Length = 1023

 Score = 70.5 bits (171), Expect = 8e-12
 Identities = 58/185 (31%), Positives = 87/185 (47%), Gaps = 10/185 (5%)

Query: 646 GQHVFGVP----PLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQ 701
           G  +FGVP    P   V   G  +P  +  A   L    +   G+FRKSG   R++ L+ 
Sbjct: 43  GGKIFGVPFNALPHSAVPEYGH-IPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALK- 99

Query: 702 MNETSPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQ 761
            N+      C       D+A LLKQ+FR+LPEPI  + L    L+  QL  +++   A  
Sbjct: 100 -NKVDHGEGCLSSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEK-NKATL 157

Query: 762 AATLLLPDENREVLQTLLYFLSDIA-SAEENQMTAGNLAVCLAPSIFHLNVSKKDSPSPR 820
             + LL D    VL+    FL +++  + EN+M + NLAV  AP++   +   +   S  
Sbjct: 158 LLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNT 217

Query: 821 IKSKR 825
            K  R
Sbjct: 218 EKKLR 222


>gi|40788018 Rho GTPase activating protein 11A isoform 2 [Homo
           sapiens]
          Length = 501

 Score = 70.5 bits (171), Expect = 8e-12
 Identities = 58/185 (31%), Positives = 87/185 (47%), Gaps = 10/185 (5%)

Query: 646 GQHVFGVP----PLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQ 701
           G  +FGVP    P   V   G  +P  +  A   L    +   G+FRKSG   R++ L+ 
Sbjct: 43  GGKIFGVPFNALPHSAVPEYGH-IPSFLVDACTSLEDH-IHTEGLFRKSGSVIRLKALK- 99

Query: 702 MNETSPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQ 761
            N+      C       D+A LLKQ+FR+LPEPI  + L    L+  QL  +++   A  
Sbjct: 100 -NKVDHGEGCLSSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEK-NKATL 157

Query: 762 AATLLLPDENREVLQTLLYFLSDIA-SAEENQMTAGNLAVCLAPSIFHLNVSKKDSPSPR 820
             + LL D    VL+    FL +++  + EN+M + NLAV  AP++   +   +   S  
Sbjct: 158 LLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNT 217

Query: 821 IKSKR 825
            K  R
Sbjct: 218 EKKLR 222


>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
          Length = 1227

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 5/183 (2%)

Query: 640  KTPDYRGQHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNL 699
            + P  +   VFGV   +  +R    +P  ++Q +  +  + +++VGI+R SGV + IQ L
Sbjct: 998  RMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQAL 1057

Query: 700  RQMNETSPD--NVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWL 757
            +   + +    +V         +A  LK YFR+LPEP+FT +    F +   L       
Sbjct: 1058 KAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKE 1117

Query: 758  AAAQAATLLLPDENREVLQTLLYFLSDIASAEE-NQMTAGNLAVCLAPSIFHLNVSKKDS 816
            +      L LP+ N      LL  L  +A  E  N+M+  NLA    P++  L  S+K+S
Sbjct: 1118 SCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTL--LRPSEKES 1175

Query: 817  PSP 819
              P
Sbjct: 1176 KLP 1178



 Score = 34.3 bits (77), Expect = 0.67
 Identities = 46/178 (25%), Positives = 63/178 (35%), Gaps = 21/178 (11%)

Query: 403 ELWSRAMYPDLGP--------GDEEEEEATSSVEIATVEVKCQAEALSQMEVPAHGESPA 454
           E W +A +PD  P        GD E+E       I  +E +   E    + +        
Sbjct: 9   EAW-KAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEK 67

Query: 455 WAQAEVQPAVLAPAQAPAEA-EPVAQEEAEAPAPAPAPAPAQDSEQEAHSGGEPTFASSL 513
            +    +      AQAP  A EP A      PAPA    P    E EA   GE    S  
Sbjct: 68  KSYDRQRWGFRRAAQAPDGASEPRASASRPQPAPADGADPPPAEEPEARPDGE---GSPG 124

Query: 514 SVEEGHSISDTVASSSELDSSGNSMNEAEAAGPLAGLQASMPRERRDSG-VGASLTRP 570
               G +     A+S E D  G           +A L+++  R R+  G  GA   +P
Sbjct: 125 KARPGTARRPGAAASGERDDRG-------PPASVAALRSNFERIRKGHGQPGADAEKP 175


>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
          Length = 1271

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 5/183 (2%)

Query: 640  KTPDYRGQHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNL 699
            + P  +   VFGV   +  +R    +P  ++Q +  +  + +++VGI+R SGV + IQ L
Sbjct: 1042 RMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQAL 1101

Query: 700  RQMNETSPD--NVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWL 757
            +   + +    +V         +A  LK YFR+LPEP+FT +    F +   L       
Sbjct: 1102 KAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKE 1161

Query: 758  AAAQAATLLLPDENREVLQTLLYFLSDIASAEE-NQMTAGNLAVCLAPSIFHLNVSKKDS 816
            +      L LP+ N      LL  L  +A  E  N+M+  NLA    P++  L  S+K+S
Sbjct: 1162 SCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTL--LRPSEKES 1219

Query: 817  PSP 819
              P
Sbjct: 1220 KLP 1222



 Score = 34.3 bits (77), Expect = 0.67
 Identities = 46/178 (25%), Positives = 63/178 (35%), Gaps = 21/178 (11%)

Query: 403 ELWSRAMYPDLGP--------GDEEEEEATSSVEIATVEVKCQAEALSQMEVPAHGESPA 454
           E W +A +PD  P        GD E+E       I  +E +   E    + +        
Sbjct: 9   EAW-KAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEK 67

Query: 455 WAQAEVQPAVLAPAQAPAEA-EPVAQEEAEAPAPAPAPAPAQDSEQEAHSGGEPTFASSL 513
            +    +      AQAP  A EP A      PAPA    P    E EA   GE    S  
Sbjct: 68  KSYDRQRWGFRRAAQAPDGASEPRASASRPQPAPADGADPPPAEEPEARPDGE---GSPG 124

Query: 514 SVEEGHSISDTVASSSELDSSGNSMNEAEAAGPLAGLQASMPRERRDSG-VGASLTRP 570
               G +     A+S E D  G           +A L+++  R R+  G  GA   +P
Sbjct: 125 KARPGTARRPGAAASGERDDRG-------PPASVAALRSNFERIRKGHGQPGADAEKP 175


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,487,599
Number of Sequences: 37866
Number of extensions: 2525132
Number of successful extensions: 19370
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 221
Number of HSP's successfully gapped in prelim test: 466
Number of HSP's that attempted gapping in prelim test: 15504
Number of HSP's gapped (non-prelim): 3244
length of query: 1103
length of database: 18,247,518
effective HSP length: 113
effective length of query: 990
effective length of database: 13,968,660
effective search space: 13828973400
effective search space used: 13828973400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.