Guide to the Human Genome
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Name: HIRA Sequence: fasta or formatted (1017aa) NCBI GI: 21536485
Description:

HIR histone cell cycle regulation defective homolog A

Referenced in:

Histones, Related Proteins, and Modifying Enzymes
WD Repeat Proteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.2         73           3
 C cysteine            2.6         26           3
 D aspartate           5.1         52           2
 E glutamate           5.4         55           3
 F phenylalanine       2.5         25           2
 G glycine             5.7         58           2
 H histidine           2.1         21           1
 I isoleucine          3.8         39           2
 K lysine              6.2         63           4
 L leucine            10.7        109           2
 M methionine          2.6         26           1
 N asparagine          3.3         34           2
 P proline             5.2         53           1
 Q glutamine           4.2         43           5
 R arginine            5.1         52           3
 S serine             10.9        111           3
 T threonine           6.1         62           2
 V valine              7.8         79           4
 W tryptophan          2.0         20           1
 Y tyrosine            1.6         16           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   HIR histone cell cycle regulation defective homolog ... 
CHAF1B                0.061   chromatin assembly factor 1 subunit B 
CIAO1                 0.028   WD repeat domain 39 
WDR51A                0.025   WD repeat domain 51A isoform 3 
WDR51A                0.025   WD repeat domain 51A isoform 2 
WDR51A                0.025   WD repeat domain 51A isoform 1 
TAF5L                 0.025   PCAF associated factor 65 beta isoform a 
NLE1                  0.024   Notchless gene homolog isoform a 
TBL1X                 0.024   transducin beta-like 1X isoform b 
TBL1X                 0.024   transducin beta-like 1X isoform b 
TBL1X                 0.024   transducin beta-like 1X isoform a 
TBL1X                 0.024   transducin beta-like 1X isoform a 
TBL1XR1               0.023   transducin (beta)-like 1 X-linked receptor 1 
KATNB1                0.023   katanin p80 subunit B 1 
TBL1Y                 0.022   transducin beta-like 1Y 
TBL1Y                 0.022   transducin beta-like 1Y 
TBL1Y                 0.022   transducin beta-like 1Y 
NLE1                  0.022   Notchless gene homolog isoform b 
CDC20                 0.022   cell division cycle 20 
WDR5B                 0.021   WD repeat domain 5B 
SNRNP40               0.020   WD repeat domain 57 (U5 snRNP specific) 
GEMIN5                0.020   gemin 5 
WDR33                 0.020   WD repeat domain 33 isoform 1 
WDR5                  0.019   WD repeat domain 5 
WDR5                  0.019   WD repeat domain 5 
WDR51B                0.019   WD repeat domain 51B 
TAF5                  0.019   TBP-associated factor 5 
BRWD1                 0.018   bromodomain and WD repeat domain containing 1 isofor...
BRWD1                 0.018   bromodomain and WD repeat domain containing 1 isofor...
PRPF4                 0.017   PRP4 pre-mRNA processing factor 4 homolog 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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