Guide to the Human Genome
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Search of human proteins with 21536402

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]
         (550 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]           1113   0.0  
gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]           1093   0.0  
gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]            999   0.0  
gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]            935   0.0  
gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]            920   0.0  
gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]            859   0.0  
gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]            849   0.0  
gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]            779   0.0  
gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]             769   0.0  
gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens]           595   e-170
gi|4502081 amphiphysin isoform 1 [Homo sapiens]                       377   e-104
gi|21536423 amphiphysin isoform 2 [Homo sapiens]                      377   e-104
gi|49472835 bridging integrator 2 [Homo sapiens]                      316   4e-86
gi|33286446 opioid growth factor receptor [Homo sapiens]               53   6e-07
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                53   8e-07
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                53   8e-07
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                53   8e-07
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   2e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    52   2e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   51   2e-06
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   51   2e-06
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   51   2e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    51   2e-06
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    51   2e-06
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             50   5e-06
gi|41281612 zinc finger protein 828 [Homo sapiens]                     50   5e-06
gi|7662236 TSC22 domain family, member 2 [Homo sapiens]                49   9e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni...    49   2e-05
gi|239742468 PREDICTED: double homeobox, 4-like [Homo sapiens]         48   2e-05
gi|194272172 double homeobox, 4 [Homo sapiens]                         48   2e-05

>gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]
          Length = 550

 Score = 1113 bits (2880), Expect = 0.0
 Identities = 550/550 (100%), Positives = 550/550 (100%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
           AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQASLLDLDFDPLPPVTS 360
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQASLLDLDFDPLPPVTS
Sbjct: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQASLLDLDFDPLPPVTS 360

Query: 361 PVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASE 420
           PVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASE
Sbjct: 361 PVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASE 420

Query: 421 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF 480
           VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF
Sbjct: 421 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF 480

Query: 481 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 540
           KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV
Sbjct: 481 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 540

Query: 541 FPENFTERVP 550
           FPENFTERVP
Sbjct: 541 FPENFTERVP 550


>gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]
          Length = 593

 Score = 1093 bits (2826), Expect = 0.0
 Identities = 550/593 (92%), Positives = 550/593 (92%), Gaps = 43/593 (7%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
           AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKS----------------------------- 331
           DGSPAATPEIRVNHEPEPAGGATPGATLPKS                             
Sbjct: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS 360

Query: 332 --------------PSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW 377
                         PSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW
Sbjct: 361 LFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW 420

Query: 378 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 437
           EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET
Sbjct: 421 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 480

Query: 438 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 497
           AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ
Sbjct: 481 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 540

Query: 498 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 550
           LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 541 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 593


>gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]
          Length = 506

 Score =  999 bits (2582), Expect = 0.0
 Identities = 506/550 (92%), Positives = 506/550 (92%), Gaps = 44/550 (8%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
           AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQASLLDLDFDPLPPVTS 360
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ                          
Sbjct: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ-------------------------- 334

Query: 361 PVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASE 420
                             PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASE
Sbjct: 335 ------------------PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASE 376

Query: 421 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF 480
           VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF
Sbjct: 377 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF 436

Query: 481 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 540
           KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV
Sbjct: 437 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 496

Query: 541 FPENFTERVP 550
           FPENFTERVP
Sbjct: 497 FPENFTERVP 506


>gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]
          Length = 518

 Score =  935 bits (2416), Expect = 0.0
 Identities = 484/561 (86%), Positives = 488/561 (86%), Gaps = 54/561 (9%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 269

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFE-----------APGPFSEQASLLD 349
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ              P    +Q  +L 
Sbjct: 270 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS 329

Query: 350 LDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAE 409
           L  D   P    +   TPS         +PTESPAGSLPSGEPSAAEGTFAVSWPSQTAE
Sbjct: 330 LFEDTFVP---EISVTTPS---------QPTESPAGSLPSGEPSAAEGTFAVSWPSQTAE 377

Query: 410 PGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGA 469
           PGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGA
Sbjct: 378 PGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGA 437

Query: 470 GRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWN 529
           GRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWN
Sbjct: 438 GRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWN 497

Query: 530 QHKELEKCRGVFPENFTERVP 550
           QHKELEKCRGVFPENFTERVP
Sbjct: 498 QHKELEKCRGVFPENFTERVP 518


>gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]
          Length = 475

 Score =  920 bits (2378), Expect = 0.0
 Identities = 475/550 (86%), Positives = 475/550 (86%), Gaps = 75/550 (13%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 269

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQASLLDLDFDPLPPVTS 360
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ                          
Sbjct: 270 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ-------------------------- 303

Query: 361 PVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASE 420
                             PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASE
Sbjct: 304 ------------------PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASE 345

Query: 421 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF 480
           VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF
Sbjct: 346 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF 405

Query: 481 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 540
           KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV
Sbjct: 406 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 465

Query: 541 FPENFTERVP 550
           FPENFTERVP
Sbjct: 466 FPENFTERVP 475


>gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]
          Length = 482

 Score =  859 bits (2220), Expect = 0.0
 Identities = 453/550 (82%), Positives = 458/550 (83%), Gaps = 68/550 (12%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 269

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQASLLDLDFDPLPPVTS 360
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ     P             P PP  +
Sbjct: 270 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPV------------PPPPKHT 317

Query: 361 PVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASE 420
           P K      Q     L+E T  P  S+ +                      P+QPAEASE
Sbjct: 318 PSKEVK---QEQILSLFEDTFVPEISVTT----------------------PSQPAEASE 352

Query: 421 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF 480
           VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF
Sbjct: 353 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF 412

Query: 481 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 540
           KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV
Sbjct: 413 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 472

Query: 541 FPENFTERVP 550
           FPENFTERVP
Sbjct: 473 FPENFTERVP 482


>gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]
          Length = 497

 Score =  849 bits (2194), Expect = 0.0
 Identities = 453/565 (80%), Positives = 458/565 (81%), Gaps = 83/565 (14%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP--------------- 285
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP               
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSKLFSRLRRKKN 269

Query: 286 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQA 345
           SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ     P     
Sbjct: 270 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPV---- 325

Query: 346 SLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPS 405
                   P PP  +P K      Q     L+E T  P  S+ +                
Sbjct: 326 --------PPPPKHTPSKEVK---QEQILSLFEDTFVPEISVTT---------------- 358

Query: 406 QTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEG 465
                 P+QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEG
Sbjct: 359 ------PSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEG 412

Query: 466 GSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKE 525
           GSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKE
Sbjct: 413 GSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKE 472

Query: 526 SDWNQHKELEKCRGVFPENFTERVP 550
           SDWNQHKELEKCRGVFPENFTERVP
Sbjct: 473 SDWNQHKELEKCRGVFPENFTERVP 497


>gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]
          Length = 439

 Score =  779 bits (2012), Expect = 0.0
 Identities = 419/550 (76%), Positives = 423/550 (76%), Gaps = 111/550 (20%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 269

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQASLLDLDFDPLPPVTS 360
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ   P   SE A               
Sbjct: 270 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ---PAEASEVAG-------------- 312

Query: 361 PVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASE 420
                              T+  AG+   GE +                        ASE
Sbjct: 313 ------------------GTQPAAGAQEPGETA------------------------ASE 330

Query: 421 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF 480
            A  + PA                     VVVETFPATVNGTVEGGSGAGRLDLPPGFMF
Sbjct: 331 AASSSLPA---------------------VVVETFPATVNGTVEGGSGAGRLDLPPGFMF 369

Query: 481 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 540
           KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV
Sbjct: 370 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 429

Query: 541 FPENFTERVP 550
           FPENFTERVP
Sbjct: 430 FPENFTERVP 439


>gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]
          Length = 454

 Score =  769 bits (1986), Expect = 0.0
 Identities = 419/565 (74%), Positives = 423/565 (74%), Gaps = 126/565 (22%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP--------------- 285
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP               
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSKLFSRLRRKKN 269

Query: 286 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQA 345
           SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ   P   SE A
Sbjct: 270 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ---PAEASEVA 326

Query: 346 SLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPS 405
                                             T+  AG+   GE +            
Sbjct: 327 G--------------------------------GTQPAAGAQEPGETA------------ 342

Query: 406 QTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEG 465
                       ASE A  + PA                     VVVETFPATVNGTVEG
Sbjct: 343 ------------ASEAASSSLPA---------------------VVVETFPATVNGTVEG 369

Query: 466 GSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKE 525
           GSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKE
Sbjct: 370 GSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKE 429

Query: 526 SDWNQHKELEKCRGVFPENFTERVP 550
           SDWNQHKELEKCRGVFPENFTERVP
Sbjct: 430 SDWNQHKELEKCRGVFPENFTERVP 454


>gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens]
          Length = 409

 Score =  595 bits (1534), Expect = e-170
 Identities = 304/338 (89%), Positives = 304/338 (89%), Gaps = 31/338 (9%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 300
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
Sbjct: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 269

Query: 301 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAP 338
           DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ   P
Sbjct: 270 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQSSLP 307



 Score =  236 bits (602), Expect = 4e-62
 Identities = 116/147 (78%), Positives = 122/147 (82%), Gaps = 1/147 (0%)

Query: 405 SQTAEPGPAQPAEASEVAGGTQPA-AGAQEPGETAASEAASSSLPAVVVETFPATVNGTV 463
           +++  P    PA   E+    +P  AG   PG T     + SSLPAVVVETFPATVNGTV
Sbjct: 263 NKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQSSLPAVVVETFPATVNGTV 322

Query: 464 EGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGV 523
           EGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGV
Sbjct: 323 EGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGV 382

Query: 524 KESDWNQHKELEKCRGVFPENFTERVP 550
           KESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 383 KESDWNQHKELEKCRGVFPENFTERVP 409


>gi|4502081 amphiphysin isoform 1 [Homo sapiens]
          Length = 695

 Score =  377 bits (969), Expect = e-104
 Identities = 244/619 (39%), Positives = 322/619 (52%), Gaps = 109/619 (17%)

Query: 9   VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
           +  G  A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q  EGTRLQ++LR Y
Sbjct: 4   IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63

Query: 69  LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
           LA++K M EAS KL E L EVYEPDW GR++   + E  D+LW D+HQKLVD +LLT+DT
Sbjct: 64  LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123

Query: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQWCQG 188
           YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+K               
Sbjct: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISK--------------- 168

Query: 189 KLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGL 248
                           AEEE  KAQKVFEE NVDLQEELPSLW+ RVGFYVNTF++++ L
Sbjct: 169 ----------------AEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSL 212

Query: 249 EENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP-DGSPAAT 307
           E  FHKE++ L   L +V+  L  QH    FT++  PSD+ P +  K+PSPP + SP  +
Sbjct: 213 EAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPS 272

Query: 308 PEIRVNH-----EPEPAGGATPGAT--------LPK------------------------ 330
           P    NH      P PA   +P  T        LPK                        
Sbjct: 273 PTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEI 332

Query: 331 ---SPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAP----TPSGQSIPWDLW----EP 379
              +PSQ E P    ++ +LLDLDFDP  P  +P  +     +P  Q++PWDLW    + 
Sbjct: 333 SVTTPSQNEVP-EVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDL 391

Query: 380 TESPAGSLPSGEPSAAEGTFAVSWPSQT-------AEPGPAQPAEASEVAGGTQPAAGAQ 432
            +  +G   +G     + +       Q+       +E  P    +A E      PA G  
Sbjct: 392 VQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLD 451

Query: 433 EPGETAASEAASSS--LPAVVVETFPATVNGTVEGGSG----AGRLDLPPGFMFKVQAQH 486
              +T A E    +  +P    +    T+    EG  G    A +  +P G    ++   
Sbjct: 452 LGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAK 511

Query: 487 DYTAT---------DTDEL-----QLKAGDVVLVIPFQNPEEQDEGWL-MGVKESDWNQH 531
             T T         + +EL     Q K    V++ P  N EE+ E  + +G +  +  + 
Sbjct: 512 IGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTED 571

Query: 532 KELEKCRGVFPENFTERVP 550
                     PE  TE+ P
Sbjct: 572 AAPPGPTSETPELATEQKP 590



 Score =  114 bits (284), Expect = 3e-25
 Identities = 71/203 (34%), Positives = 99/203 (48%), Gaps = 20/203 (9%)

Query: 363 KAPTPSGQSIPWDL----WEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEA 418
           KA  P+G+ +  +      E TE    + P  E   A        PS   EP      E 
Sbjct: 496 KATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEG 555

Query: 419 -SEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD---- 473
            +E+  G +P    +E  E AA    +S  P +  E  P             G  D    
Sbjct: 556 ENEITIGAEP----KETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLAS 611

Query: 474 -------LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKES 526
                  LPPGF++KV+  HD+ A ++DEL L+ GDVVLV+P  +  +QD GWL+GVKES
Sbjct: 612 AREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKES 671

Query: 527 DWNQHKELEKCRGVFPENFTERV 549
           DW Q+++L   +G+FPENFT R+
Sbjct: 672 DWLQYRDLATYKGLFPENFTRRL 694



 Score = 29.3 bits (64), Expect = 9.8
 Identities = 36/144 (25%), Positives = 56/144 (38%), Gaps = 17/144 (11%)

Query: 232 NSRVGFYVNTFQSIAGLEENFHKEMSKLNQ--NLNDVLVGLEKQHGSNTFTVKAQPSDNA 289
           ++ VG  V+  +   G E    K      +  +L +  +G E   G+ +    AQP    
Sbjct: 474 DAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAES----AQPE--- 526

Query: 290 PAKGNKSPSPPDGS-PAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQASLL 348
            A+  ++  P +   P+   E   NHE E     T GA   ++      PGP SE   L 
Sbjct: 527 -AEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELA 585

Query: 349 DLDFDPLPPVTSPVKAPTPSGQSI 372
                   P+  P   PTPS  ++
Sbjct: 586 ----TEQKPIQDP--QPTPSAPAM 603


>gi|21536423 amphiphysin isoform 2 [Homo sapiens]
          Length = 653

 Score =  377 bits (968), Expect = e-104
 Identities = 242/592 (40%), Positives = 316/592 (53%), Gaps = 97/592 (16%)

Query: 9   VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
           +  G  A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q  EGTRLQ++LR Y
Sbjct: 4   IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63

Query: 69  LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
           LA++K M EAS KL E L EVYEPDW GR++   + E  D+LW D+HQKLVD +LLT+DT
Sbjct: 64  LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123

Query: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQWCQG 188
           YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+K               
Sbjct: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISK--------------- 168

Query: 189 KLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGL 248
                           AEEE  KAQKVFEE NVDLQEELPSLW+ RVGFYVNTF++++ L
Sbjct: 169 ----------------AEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSL 212

Query: 249 EENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP-DGSPAAT 307
           E  FHKE++ L   L +V+  L  QH    FT++  PSD+ P +  K+PSPP + SP  +
Sbjct: 213 EAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPS 272

Query: 308 PEIRVNH-----EPEPAGGATPGAT--------LPK------------------------ 330
           P    NH      P PA   +P  T        LPK                        
Sbjct: 273 PTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEI 332

Query: 331 ---SPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAP----TPSGQSIPWDLW----EP 379
              +PSQ E P    ++ +LLDLDFDP  P  +P  +     +P  Q++PWDLW    + 
Sbjct: 333 SVTTPSQNEVP-EVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDL 391

Query: 380 TESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAA 439
            +  +G   +G     + +       Q+       P   ++ A GT  +A    PGE A 
Sbjct: 392 VQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLIIPGADADAAVGTLVSAAEGAPGEEA- 450

Query: 440 SEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLK 499
            EA  +++PA    +      GT E   GA              AQ +    +    Q K
Sbjct: 451 -EAEKATVPAGEGVSLEEAKIGT-ETTEGA------------ESAQPEAEELEATVPQEK 496

Query: 500 AGDVVLVIPFQNPEEQDEGWL-MGVKESDWNQHKELEKCRGVFPENFTERVP 550
               V++ P  N EE+ E  + +G +  +  +           PE  TE+ P
Sbjct: 497 VIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKP 548



 Score =  114 bits (284), Expect = 3e-25
 Identities = 71/203 (34%), Positives = 99/203 (48%), Gaps = 20/203 (9%)

Query: 363 KAPTPSGQSIPWDL----WEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEA 418
           KA  P+G+ +  +      E TE    + P  E   A        PS   EP      E 
Sbjct: 454 KATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEG 513

Query: 419 -SEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD---- 473
            +E+  G +P    +E  E AA    +S  P +  E  P             G  D    
Sbjct: 514 ENEITIGAEP----KETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLAS 569

Query: 474 -------LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKES 526
                  LPPGF++KV+  HD+ A ++DEL L+ GDVVLV+P  +  +QD GWL+GVKES
Sbjct: 570 AREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKES 629

Query: 527 DWNQHKELEKCRGVFPENFTERV 549
           DW Q+++L   +G+FPENFT R+
Sbjct: 630 DWLQYRDLATYKGLFPENFTRRL 652


>gi|49472835 bridging integrator 2 [Homo sapiens]
          Length = 565

 Score =  316 bits (809), Expect = 4e-86
 Identities = 198/470 (42%), Positives = 264/470 (56%), Gaps = 56/470 (11%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAE G  G  AG  A  VQKK +RAQEKVLQKLGKA ETKDE+FEQ   NF +Q  EG +
Sbjct: 1   MAE-GKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHK 59

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           L KDL+ +L++VK MHE+SK+++E LQE+Y  +W G +E   I  NNDLLW DY +KL D
Sbjct: 60  LYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLAD 119

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
           QA+ TM+ Y+ QF +IK RIAKRGRKLVDYDSARHH E++Q AKKKDEAK AK       
Sbjct: 120 QAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAK------- 172

Query: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
                                   AEEE  KAQ VFE++N +L EELP L+NSR+G YV 
Sbjct: 173 ------------------------AEEEFNKAQTVFEDLNQELLEELPILYNSRIGCYVT 208

Query: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDN------APAKGN 294
            FQ+I+ L + F++EMSKLN NL +V+  LEKQH +  F VK   S +      +P    
Sbjct: 209 IFQNISNLRDVFYREMSKLNHNLYEVMSKLEKQHSNKVFVVKGLSSSSRRSLVISPPVRT 268

Query: 295 KSPSPPDGSPAATPEIRVNHEPEPAGGA---TPGATLPKSPSQF------EAPGPFSEQA 345
            + S P  SP +   + +  E E         P A   +  S+       E       +A
Sbjct: 269 ATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKEGSEA 328

Query: 346 SLLDLDFDPLPPVTSPVKA-PTPSGQSIPWD----LWEPTESPAGSL-PSGEPSAAEGTF 399
           S  + D +PLP    P +A P+P+ +             T SP G+L PSG+PS++    
Sbjct: 329 SSSEED-EPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSS--AT 385

Query: 400 AVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPA 449
            V   ++TA  G  QP + + +   + P +    P  TA+   +S ++P+
Sbjct: 386 EVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPS 435



 Score = 29.3 bits (64), Expect = 9.8
 Identities = 35/137 (25%), Positives = 47/137 (34%), Gaps = 16/137 (11%)

Query: 284 QPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSE 343
           QP   A  +   +P      P+  P  R    P P+ G      +P SP+      P S 
Sbjct: 400 QPKKRASIQRTSAP------PSRPPPPRATASPRPSSG-----NIPSSPTASGGGSPTSP 448

Query: 344 QASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSW 403
           +ASL         P TS   +P P     P    E  E+      + E      T   S 
Sbjct: 449 RASL---GTGTASPRTSLEVSPNPEPPEKPVRTPEAKENENIHNQNPEELCTSPTLMTS- 504

Query: 404 PSQTAEPGPAQPAEASE 420
               +EPG A+  E  E
Sbjct: 505 -QVASEPGEAKKMEDKE 520


>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 52/177 (29%), Positives = 67/177 (37%), Gaps = 29/177 (16%)

Query: 285 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHE---PEPAGGATPGATLPKSPSQFEAPGPF 341
           P +  P   +++P P    PA         E   P PAG A  G    +SPS+   P P 
Sbjct: 510 PKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPA--GDEPAESPSETPGPRPA 567

Query: 342 SEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAV 401
                          P  SP + P PS      D  EP ESP+ + P   P+   G    
Sbjct: 568 GPAGD---------EPAESPSETPGPSPAGPTRD--EPAESPSET-PGPRPAGPAGDEPA 615

Query: 402 SWPSQTAEPGPA-----QPAEASEVAGGTQPA-------AGAQEPGETAASEAASSS 446
             PS+T  P PA     +PAE+     G  PA       A A E  E   +E  SS+
Sbjct: 616 ESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSA 672



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 31/101 (30%), Positives = 38/101 (37%), Gaps = 11/101 (10%)

Query: 379 PTESPAGS---LPSGEPSAAEGTFAVSWPSQTAEPGPA-----QPAEASEVAGGTQPAAG 430
           P E   GS    P   P+   G      PS+T  P PA     +PAE+     G +PA  
Sbjct: 510 PKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGP 569

Query: 431 A-QEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAG 470
           A  EP E+ +     S  PA      PA       G   AG
Sbjct: 570 AGDEPAESPSETPGPS--PAGPTRDEPAESPSETPGPRPAG 608


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 48/219 (21%), Positives = 81/219 (36%), Gaps = 4/219 (1%)

Query: 226 ELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHG-SNTFTVKAQ 284
           ++PS+        + T  ++  L +N     S+ N N +  +  L   +  +   T  A 
Sbjct: 110 QIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP 169

Query: 285 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQ 344
           P+ +A      S S P  + AA P      +  P+  A P  T          P P S  
Sbjct: 170 PTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSS 229

Query: 345 ASLLDLDFDPLPPVTSPV---KAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAV 401
           A        P P  T+P     +  P   ++P      T  P+ +    E +AA  T + 
Sbjct: 230 APPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSA 289

Query: 402 SWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAAS 440
           + P+  + P P +   A      + P   A +  ET+A+
Sbjct: 290 TTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAA 328



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 44/182 (24%), Positives = 61/182 (33%), Gaps = 32/182 (17%)

Query: 277 NTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFE 336
           N  T+ ++  +N     + +   P  SPA         +   A   TP AT P  PS   
Sbjct: 135 NATTISSR--ENVNTSSSVATLAPVNSPAP--------QDTTAAPPTPSATTPAPPSSSA 184

Query: 337 APGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGS-LPSGEPSAA 395
            P            +    PP  S      PS  + P     P   PA +  P    +  
Sbjct: 185 PP------------ETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPP 232

Query: 396 EGTFAVSWPSQTAEPGPAQPAEASEV--------AGGTQPAAGAQEPGETAASEAASSSL 447
           E T A   PS T  P P   +   E         A    P++ +  P  TAA    S++ 
Sbjct: 233 ETTAAPPTPSATT-PAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATT 291

Query: 448 PA 449
           PA
Sbjct: 292 PA 293



 Score = 30.4 bits (67), Expect = 4.4
 Identities = 41/161 (25%), Positives = 57/161 (35%), Gaps = 15/161 (9%)

Query: 299 PPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQASLLDLDFDPLPPV 358
           PP  SP   P+    H+P            P   +  + P      AS        LP V
Sbjct: 75  PP--SPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSAST---KITTLPNV 129

Query: 359 TS-PVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAE 417
           T  P  A T S +    +    + S A   P   P+  + T A   PS T    P+  A 
Sbjct: 130 TFLPQNATTISSR----ENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAP 185

Query: 418 ASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPAT 458
               A    P+A  Q P  ++A    +++ P     T PAT
Sbjct: 186 PETTAAPPTPSATTQAPPSSSAPPETTAAPP-----TPPAT 221


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 48/219 (21%), Positives = 81/219 (36%), Gaps = 4/219 (1%)

Query: 226 ELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHG-SNTFTVKAQ 284
           ++PS+        + T  ++  L +N     S+ N N +  +  L   +  +   T  A 
Sbjct: 110 QIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP 169

Query: 285 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQ 344
           P+ +A      S S P  + AA P      +  P+  A P  T          P P S  
Sbjct: 170 PTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSS 229

Query: 345 ASLLDLDFDPLPPVTSPV---KAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAV 401
           A        P P  T+P     +  P   ++P      T  P+ +    E +AA  T + 
Sbjct: 230 APPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSA 289

Query: 402 SWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAAS 440
           + P+  + P P +   A      + P   A +  ET+A+
Sbjct: 290 TTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAA 328



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 44/182 (24%), Positives = 61/182 (33%), Gaps = 32/182 (17%)

Query: 277 NTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFE 336
           N  T+ ++  +N     + +   P  SPA         +   A   TP AT P  PS   
Sbjct: 135 NATTISSR--ENVNTSSSVATLAPVNSPAP--------QDTTAAPPTPSATTPAPPSSSA 184

Query: 337 APGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGS-LPSGEPSAA 395
            P            +    PP  S      PS  + P     P   PA +  P    +  
Sbjct: 185 PP------------ETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPP 232

Query: 396 EGTFAVSWPSQTAEPGPAQPAEASEV--------AGGTQPAAGAQEPGETAASEAASSSL 447
           E T A   PS T  P P   +   E         A    P++ +  P  TAA    S++ 
Sbjct: 233 ETTAAPPTPSATT-PAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATT 291

Query: 448 PA 449
           PA
Sbjct: 292 PA 293



 Score = 30.4 bits (67), Expect = 4.4
 Identities = 41/161 (25%), Positives = 57/161 (35%), Gaps = 15/161 (9%)

Query: 299 PPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQASLLDLDFDPLPPV 358
           PP  SP   P+    H+P            P   +  + P      AS        LP V
Sbjct: 75  PP--SPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSAST---KITTLPNV 129

Query: 359 TS-PVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAE 417
           T  P  A T S +    +    + S A   P   P+  + T A   PS T    P+  A 
Sbjct: 130 TFLPQNATTISSR----ENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAP 185

Query: 418 ASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPAT 458
               A    P+A  Q P  ++A    +++ P     T PAT
Sbjct: 186 PETTAAPPTPSATTQAPPSSSAPPETTAAPP-----TPPAT 221


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 48/219 (21%), Positives = 81/219 (36%), Gaps = 4/219 (1%)

Query: 226 ELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHG-SNTFTVKAQ 284
           ++PS+        + T  ++  L +N     S+ N N +  +  L   +  +   T  A 
Sbjct: 110 QIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP 169

Query: 285 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQ 344
           P+ +A      S S P  + AA P      +  P+  A P  T          P P S  
Sbjct: 170 PTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSS 229

Query: 345 ASLLDLDFDPLPPVTSPV---KAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAV 401
           A        P P  T+P     +  P   ++P      T  P+ +    E +AA  T + 
Sbjct: 230 APPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSA 289

Query: 402 SWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAAS 440
           + P+  + P P +   A      + P   A +  ET+A+
Sbjct: 290 TTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAA 328



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 44/182 (24%), Positives = 61/182 (33%), Gaps = 32/182 (17%)

Query: 277 NTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFE 336
           N  T+ ++  +N     + +   P  SPA         +   A   TP AT P  PS   
Sbjct: 135 NATTISSR--ENVNTSSSVATLAPVNSPAP--------QDTTAAPPTPSATTPAPPSSSA 184

Query: 337 APGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGS-LPSGEPSAA 395
            P            +    PP  S      PS  + P     P   PA +  P    +  
Sbjct: 185 PP------------ETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPP 232

Query: 396 EGTFAVSWPSQTAEPGPAQPAEASEV--------AGGTQPAAGAQEPGETAASEAASSSL 447
           E T A   PS T  P P   +   E         A    P++ +  P  TAA    S++ 
Sbjct: 233 ETTAAPPTPSATT-PAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATT 291

Query: 448 PA 449
           PA
Sbjct: 292 PA 293



 Score = 30.4 bits (67), Expect = 4.4
 Identities = 41/161 (25%), Positives = 57/161 (35%), Gaps = 15/161 (9%)

Query: 299 PPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQASLLDLDFDPLPPV 358
           PP  SP   P+    H+P            P   +  + P      AS        LP V
Sbjct: 75  PP--SPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSAST---KITTLPNV 129

Query: 359 TS-PVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAE 417
           T  P  A T S +    +    + S A   P   P+  + T A   PS T    P+  A 
Sbjct: 130 TFLPQNATTISSR----ENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAP 185

Query: 418 ASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPAT 458
               A    P+A  Q P  ++A    +++ P     T PAT
Sbjct: 186 PETTAAPPTPSATTQAPPSSSAPPETTAAPP-----TPPAT 221


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 56/201 (27%), Positives = 71/201 (35%), Gaps = 27/201 (13%)

Query: 281 VKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPE---PAGGATPGATLPKSPSQFEA 337
           V   P  + P   + +P P    P A P +++   P    PA    P   LP  P+ F  
Sbjct: 481 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 540

Query: 338 PGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEG 397
             PFS  ASL        PP   PV A  P  Q  P     P  SP    P   P+    
Sbjct: 541 QAPFSPSASLPMSPLATPPPQAPPVLA-APLLQVPP----SPPASPTLQAPRRPPTPGPD 595

Query: 398 TFAVSWPSQT--AEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETF 455
           T +VS P  T    PGP  P   S       P++    P     S +A+S+         
Sbjct: 596 T-SVSGPRLTLALAPGPPPPPSRS-------PSSTLSGPDLAGHSSSATST--------- 638

Query: 456 PATVNGTVEGGSGAGRLDLPP 476
           P  + G   G  G      PP
Sbjct: 639 PEELRGYDSGPEGGAAASPPP 659



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 59/221 (26%), Positives = 81/221 (36%), Gaps = 49/221 (22%)

Query: 283 AQPSDNAPAKGNKSPSPPDGSPA------ATPEIRVNHEPEPAGGATPGATLP------- 329
           A PS +AP      PSPP   P+       +P ++  H   P+   +P AT P       
Sbjct: 341 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 400

Query: 330 -----KSPSQFEAPGPFSEQAS------------LLDLDFDP--LPPVTSPVKAP----- 365
                ++P    A  P S  A+            LL   F P   PPV +P   P     
Sbjct: 401 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 460

Query: 366 ----TPSGQSIPWDLWEPTESPAG--SLPSGEPSAAEGTFA----VSWPSQTAEPGPAQP 415
               TP  Q+ P     P + P    + P   PSA     A     + P Q A+P P  P
Sbjct: 461 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 520

Query: 416 AEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 456
              +       P+  A  PG+  A  + S+SLP   + T P
Sbjct: 521 PALATPPLQALPSPPASFPGQ--APFSPSASLPMSPLATPP 559



 Score = 32.7 bits (73), Expect = 0.88
 Identities = 45/192 (23%), Positives = 72/192 (37%), Gaps = 32/192 (16%)

Query: 297 PSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQASLLDLDFDPLP 356
           P PP  SP++T        P+ AG ++   + P+    +++ GP    A+         P
Sbjct: 612 PPPPSRSPSSTLS-----GPDLAGHSSSATSTPEELRGYDS-GPEGGAAAS--------P 657

Query: 357 PVTSPVKAPTPS----GQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAV----SWPSQTA 408
           P  + + A  P+    G + P        +P    P+  P +A+G   +       S T 
Sbjct: 658 PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 717

Query: 409 EPGPAQPAEASEVAGGTQPA-----AGAQEPGETAASEAASSSLPAVVVE-----TFPAT 458
            PG   P  +   +GG   A     A ++ P +    E    +L A VV+     T    
Sbjct: 718 APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLA 777

Query: 459 VNGTVEGGSGAG 470
                 GGSG G
Sbjct: 778 AAEGAAGGSGGG 789



 Score = 30.4 bits (67), Expect = 4.4
 Identities = 48/203 (23%), Positives = 61/203 (30%), Gaps = 45/203 (22%)

Query: 280 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS-------- 331
           T    P+   PA G    +PP  + +  P   V+     +G   PG    K         
Sbjct: 85  TSSRNPASRPPASGRGERAPPAKNTSPGP---VSSPGRASGTTRPGPLGQKGLRISAEET 141

Query: 332 ---PSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKA--------------PTPSGQSIPW 374
                  EAP   +  A        P P   SP  A              P PS +  P 
Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP- 200

Query: 375 DLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEP 434
               PTE P  S+ S    +            T EP PA     S   G  +PA+ +   
Sbjct: 201 ----PTEGPRKSVSSASEHS------------TTEPSPAARRRPSAGGGLQRPASRSLSS 244

Query: 435 GETAASEAASSSLPAVVVETFPA 457
             T  S  A S   A      PA
Sbjct: 245 SATPLSSPARSGPSARGTPRAPA 267


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 56/201 (27%), Positives = 71/201 (35%), Gaps = 27/201 (13%)

Query: 281 VKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPE---PAGGATPGATLPKSPSQFEA 337
           V   P  + P   + +P P    P A P +++   P    PA    P   LP  P+ F  
Sbjct: 442 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 501

Query: 338 PGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEG 397
             PFS  ASL        PP   PV A  P  Q  P     P  SP    P   P+    
Sbjct: 502 QAPFSPSASLPMSPLATPPPQAPPVLA-APLLQVPP----SPPASPTLQAPRRPPTPGPD 556

Query: 398 TFAVSWPSQT--AEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETF 455
           T +VS P  T    PGP  P   S       P++    P     S +A+S+         
Sbjct: 557 T-SVSGPRLTLALAPGPPPPPSRS-------PSSTLSGPDLAGHSSSATST--------- 599

Query: 456 PATVNGTVEGGSGAGRLDLPP 476
           P  + G   G  G      PP
Sbjct: 600 PEELRGYDSGPEGGAAASPPP 620



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 59/221 (26%), Positives = 81/221 (36%), Gaps = 49/221 (22%)

Query: 283 AQPSDNAPAKGNKSPSPPDGSPA------ATPEIRVNHEPEPAGGATPGATLP------- 329
           A PS +AP      PSPP   P+       +P ++  H   P+   +P AT P       
Sbjct: 302 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 361

Query: 330 -----KSPSQFEAPGPFSEQAS------------LLDLDFDP--LPPVTSPVKAP----- 365
                ++P    A  P S  A+            LL   F P   PPV +P   P     
Sbjct: 362 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 421

Query: 366 ----TPSGQSIPWDLWEPTESPAG--SLPSGEPSAAEGTFA----VSWPSQTAEPGPAQP 415
               TP  Q+ P     P + P    + P   PSA     A     + P Q A+P P  P
Sbjct: 422 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 481

Query: 416 AEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 456
              +       P+  A  PG+  A  + S+SLP   + T P
Sbjct: 482 PALATPPLQALPSPPASFPGQ--APFSPSASLPMSPLATPP 520



 Score = 32.7 bits (73), Expect = 0.88
 Identities = 45/153 (29%), Positives = 58/153 (37%), Gaps = 23/153 (15%)

Query: 283 AQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFS 342
           A PS   P KG ++  PP  +P              +  ATP  + P SPS   AP    
Sbjct: 258 AHPSQPKP-KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS---AP---- 309

Query: 343 EQASLLDLDFDPLPPVTSPVKAPT----PSGQSIPWDLWEPTESPAGSLPSGEPSAAEGT 398
              SL  L   P PP T P +A T    P+ Q+    L  P  SP  + P   P      
Sbjct: 310 --PSLQTL---PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP----- 359

Query: 399 FAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGA 431
            A++ P   A P P      S +A  +  A  A
Sbjct: 360 -ALALPPLQAPPSPPASPPLSPLATPSPQAPNA 391



 Score = 32.7 bits (73), Expect = 0.88
 Identities = 45/192 (23%), Positives = 72/192 (37%), Gaps = 32/192 (16%)

Query: 297 PSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQASLLDLDFDPLP 356
           P PP  SP++T        P+ AG ++   + P+    +++ GP    A+         P
Sbjct: 573 PPPPSRSPSSTLS-----GPDLAGHSSSATSTPEELRGYDS-GPEGGAAAS--------P 618

Query: 357 PVTSPVKAPTPS----GQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAV----SWPSQTA 408
           P  + + A  P+    G + P        +P    P+  P +A+G   +       S T 
Sbjct: 619 PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 678

Query: 409 EPGPAQPAEASEVAGGTQPA-----AGAQEPGETAASEAASSSLPAVVVE-----TFPAT 458
            PG   P  +   +GG   A     A ++ P +    E    +L A VV+     T    
Sbjct: 679 APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLA 738

Query: 459 VNGTVEGGSGAG 470
                 GGSG G
Sbjct: 739 AAEGAAGGSGGG 750


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 50/189 (26%), Positives = 66/189 (34%), Gaps = 13/189 (6%)

Query: 282 KAQPSDNAP-AKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQF---EA 337
           K    D AP +K    P+P   +    P +    EP P     P +T PK P+      A
Sbjct: 181 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 240

Query: 338 PGPFSEQASLLDLDFDPLP----PVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPS 393
           P    E A          P    P T+   APT   +  P    EP  +   S P+    
Sbjct: 241 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 300

Query: 394 AAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSS----LPA 449
            A  T     P+   EP P  P E +      +PA   +EP  T   E A ++     P 
Sbjct: 301 PAPTTPKKPAPTTPKEPAPTTPKEPTPTT-PKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 359

Query: 450 VVVETFPAT 458
              E  P T
Sbjct: 360 TPKEPAPTT 368



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 47/184 (25%), Positives = 63/184 (34%), Gaps = 22/184 (11%)

Query: 280 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPG 339
           T   +P+   P    K P+P    PA T       EP P     P  T PK P    AP 
Sbjct: 320 TTPKEPTPTTP----KEPAPTTKEPAPTTP----KEPAPTAPKKPAPTTPKEP----APT 367

Query: 340 PFSEQASLLDLDFDPLPPVTSPVKAPTPSG-QSIPWDLWEPTESPAGSLPSGEPSAAEGT 398
              E A     +  P  P     K P P+  +S P    EP  +   S P+     +  T
Sbjct: 368 TPKEPAPTTTKEPSPTTP-----KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 422

Query: 399 FAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSS----LPAVVVET 454
                P+   EP P  P + +            +EP  T   + A ++     P    ET
Sbjct: 423 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 482

Query: 455 FPAT 458
            P T
Sbjct: 483 APTT 486



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 48/181 (26%), Positives = 67/181 (37%), Gaps = 15/181 (8%)

Query: 285 PSDNAPAKGNK-SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSE 343
           P + AP    K +P+ P+     TPE      PE     TP    P +P   E P P + 
Sbjct: 479 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP---EEPAPTTP 535

Query: 344 QASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSW 403
           +A+  +   +P P  T+P K P P+    P     PT +P  + P+     A  T     
Sbjct: 536 KAAAPNTPKEPAP--TTP-KEPAPTTPKEP----APT-TPKETAPTTPKGTAPTTLKEPA 587

Query: 404 PSQTAEPGPAQ--PAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNG 461
           P+   +P P +  P    E    T        P  TA +       P    E  P T  G
Sbjct: 588 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT-TPKEPAPTTPKEPAPTTPKG 646

Query: 462 T 462
           T
Sbjct: 647 T 647



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 48/202 (23%), Positives = 67/202 (33%), Gaps = 19/202 (9%)

Query: 280 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPS-QFEAP 338
           T   +P+         +P  P  +    P      EP P     P  T PK P+   + P
Sbjct: 281 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 340

Query: 339 GPFSEQASLLDLDFDPLP-------PVTSPVKAPTPSGQSIPWDLWEPTESPAGSLP--S 389
            P + +         P P       P T    APT + +  P    EP  +   S P  +
Sbjct: 341 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 400

Query: 390 GEPS-----AAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAAS 444
            EP+     +A  T     P+ T EP P  P E +            +EP  T   E A 
Sbjct: 401 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 460

Query: 445 SS----LPAVVVETFPATVNGT 462
           ++     P    E  P T   T
Sbjct: 461 TTTKKPAPTTPKEPAPTTPKET 482



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 46/178 (25%), Positives = 63/178 (35%), Gaps = 19/178 (10%)

Query: 285 PSDNAPAKGNK-SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSE 343
           P   AP    K +P+ P+     TPE      PE     TP A  P +P +   P P + 
Sbjct: 495 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE---PAPTTP 551

Query: 344 QASLLDLDFDPLP-------PVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSA-- 394
           +        +P P       P T    APT   +  P    +P         + EP++  
Sbjct: 552 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 611

Query: 395 ----AEGTFAVSWPSQTAEPGPAQPAE-ASEVAGGTQPAAGAQEPGETAASEAASSSL 447
               A  T   + P+   EP P  P E A     GT P    +EP  T   + A   L
Sbjct: 612 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT-LKEPAPTTPKKPAPKEL 668



 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 50/181 (27%), Positives = 69/181 (38%), Gaps = 24/181 (13%)

Query: 285 PSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGAT--PGATLPKS-PSQFEAPGP 340
           P + AP     +P+ P + +P  T E       EPA   T  P  T  KS P+  + P P
Sbjct: 244 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 303

Query: 341 FSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFA 400
            + +        +P P  T+P K PTP+    P +    T+ PA + P      A    A
Sbjct: 304 TTPKKPAPTTPKEPAP--TTP-KEPTPT---TPKEPAPTTKEPAPTTPKEPAPTAPKKPA 357

Query: 401 VSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAA---SSSLPAVVVETFPA 457
              P+   EP P  P E +            +EP  T   E A   + S P    E  P 
Sbjct: 358 ---PTTPKEPAPTTPKEPAPTT--------TKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 406

Query: 458 T 458
           T
Sbjct: 407 T 407



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 50/182 (27%), Positives = 69/182 (37%), Gaps = 26/182 (14%)

Query: 285 PSDNAPAKGNKSPSPPDGSPAAT----PEIRVNHEPEPAGGATPGATLPKSPSQF--EAP 338
           P + AP     +P+ P   PA T    P      EP P     P  T  K PS    + P
Sbjct: 330 PKEPAPTTKEPAPTTPK-EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 388

Query: 339 GPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEP----TESPAGSLPSGEPSA 394
            P + +++          P T+   APT + +S P    EP    T+ PA + P  EP  
Sbjct: 389 APTTTKSA----------PTTTKEPAPTTT-KSAPTTPKEPSPTTTKEPAPTTPK-EP-- 434

Query: 395 AEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVET 454
           A  T     P+   EP P  P E +            +EP  T   E A ++ P  +  T
Sbjct: 435 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT-PKKLTPT 493

Query: 455 FP 456
            P
Sbjct: 494 TP 495


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 50/189 (26%), Positives = 66/189 (34%), Gaps = 13/189 (6%)

Query: 282 KAQPSDNAP-AKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQF---EA 337
           K    D AP +K    P+P   +    P +    EP P     P +T PK P+      A
Sbjct: 222 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 281

Query: 338 PGPFSEQASLLDLDFDPLP----PVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPS 393
           P    E A          P    P T+   APT   +  P    EP  +   S P+    
Sbjct: 282 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 341

Query: 394 AAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSS----LPA 449
            A  T     P+   EP P  P E +      +PA   +EP  T   E A ++     P 
Sbjct: 342 PAPTTPKKPAPTTPKEPAPTTPKEPTPTT-PKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 400

Query: 450 VVVETFPAT 458
              E  P T
Sbjct: 401 TPKEPAPTT 409



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 47/184 (25%), Positives = 63/184 (34%), Gaps = 22/184 (11%)

Query: 280 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPG 339
           T   +P+   P    K P+P    PA T       EP P     P  T PK P    AP 
Sbjct: 361 TTPKEPTPTTP----KEPAPTTKEPAPTTP----KEPAPTAPKKPAPTTPKEP----APT 408

Query: 340 PFSEQASLLDLDFDPLPPVTSPVKAPTPSG-QSIPWDLWEPTESPAGSLPSGEPSAAEGT 398
              E A     +  P  P     K P P+  +S P    EP  +   S P+     +  T
Sbjct: 409 TPKEPAPTTTKEPSPTTP-----KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 463

Query: 399 FAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSS----LPAVVVET 454
                P+   EP P  P + +            +EP  T   + A ++     P    ET
Sbjct: 464 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 523

Query: 455 FPAT 458
            P T
Sbjct: 524 APTT 527



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 48/181 (26%), Positives = 67/181 (37%), Gaps = 15/181 (8%)

Query: 285 PSDNAPAKGNK-SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSE 343
           P + AP    K +P+ P+     TPE      PE     TP    P +P   E P P + 
Sbjct: 520 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP---EEPAPTTP 576

Query: 344 QASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSW 403
           +A+  +   +P P  T+P K P P+    P     PT +P  + P+     A  T     
Sbjct: 577 KAAAPNTPKEPAP--TTP-KEPAPTTPKEP----APT-TPKETAPTTPKGTAPTTLKEPA 628

Query: 404 PSQTAEPGPAQ--PAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNG 461
           P+   +P P +  P    E    T        P  TA +       P    E  P T  G
Sbjct: 629 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT-TPKEPAPTTPKEPAPTTPKG 687

Query: 462 T 462
           T
Sbjct: 688 T 688



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 48/202 (23%), Positives = 67/202 (33%), Gaps = 19/202 (9%)

Query: 280 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPS-QFEAP 338
           T   +P+         +P  P  +    P      EP P     P  T PK P+   + P
Sbjct: 322 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 381

Query: 339 GPFSEQASLLDLDFDPLP-------PVTSPVKAPTPSGQSIPWDLWEPTESPAGSLP--S 389
            P + +         P P       P T    APT + +  P    EP  +   S P  +
Sbjct: 382 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 441

Query: 390 GEPS-----AAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAAS 444
            EP+     +A  T     P+ T EP P  P E +            +EP  T   E A 
Sbjct: 442 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 501

Query: 445 SS----LPAVVVETFPATVNGT 462
           ++     P    E  P T   T
Sbjct: 502 TTTKKPAPTTPKEPAPTTPKET 523



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 46/178 (25%), Positives = 63/178 (35%), Gaps = 19/178 (10%)

Query: 285 PSDNAPAKGNK-SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSE 343
           P   AP    K +P+ P+     TPE      PE     TP A  P +P +   P P + 
Sbjct: 536 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE---PAPTTP 592

Query: 344 QASLLDLDFDPLP-------PVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSA-- 394
           +        +P P       P T    APT   +  P    +P         + EP++  
Sbjct: 593 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 652

Query: 395 ----AEGTFAVSWPSQTAEPGPAQPAE-ASEVAGGTQPAAGAQEPGETAASEAASSSL 447
               A  T   + P+   EP P  P E A     GT P    +EP  T   + A   L
Sbjct: 653 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT-LKEPAPTTPKKPAPKEL 709



 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 50/181 (27%), Positives = 69/181 (38%), Gaps = 24/181 (13%)

Query: 285 PSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGAT--PGATLPKS-PSQFEAPGP 340
           P + AP     +P+ P + +P  T E       EPA   T  P  T  KS P+  + P P
Sbjct: 285 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 344

Query: 341 FSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFA 400
            + +        +P P  T+P K PTP+    P +    T+ PA + P      A    A
Sbjct: 345 TTPKKPAPTTPKEPAP--TTP-KEPTPT---TPKEPAPTTKEPAPTTPKEPAPTAPKKPA 398

Query: 401 VSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAA---SSSLPAVVVETFPA 457
              P+   EP P  P E +            +EP  T   E A   + S P    E  P 
Sbjct: 399 ---PTTPKEPAPTTPKEPAPTT--------TKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 447

Query: 458 T 458
           T
Sbjct: 448 T 448



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 50/182 (27%), Positives = 69/182 (37%), Gaps = 26/182 (14%)

Query: 285 PSDNAPAKGNKSPSPPDGSPAAT----PEIRVNHEPEPAGGATPGATLPKSPSQF--EAP 338
           P + AP     +P+ P   PA T    P      EP P     P  T  K PS    + P
Sbjct: 371 PKEPAPTTKEPAPTTPK-EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 429

Query: 339 GPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEP----TESPAGSLPSGEPSA 394
            P + +++          P T+   APT + +S P    EP    T+ PA + P  EP  
Sbjct: 430 APTTTKSA----------PTTTKEPAPTTT-KSAPTTPKEPSPTTTKEPAPTTPK-EP-- 475

Query: 395 AEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVET 454
           A  T     P+   EP P  P E +            +EP  T   E A ++ P  +  T
Sbjct: 476 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT-PKKLTPT 534

Query: 455 FP 456
            P
Sbjct: 535 TP 536


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 50/189 (26%), Positives = 66/189 (34%), Gaps = 13/189 (6%)

Query: 282 KAQPSDNAP-AKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQF---EA 337
           K    D AP +K    P+P   +    P +    EP P     P +T PK P+      A
Sbjct: 274 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 333

Query: 338 PGPFSEQASLLDLDFDPLP----PVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPS 393
           P    E A          P    P T+   APT   +  P    EP  +   S P+    
Sbjct: 334 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 393

Query: 394 AAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSS----LPA 449
            A  T     P+   EP P  P E +      +PA   +EP  T   E A ++     P 
Sbjct: 394 PAPTTPKKPAPTTPKEPAPTTPKEPTPTT-PKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 452

Query: 450 VVVETFPAT 458
              E  P T
Sbjct: 453 TPKEPAPTT 461



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 47/184 (25%), Positives = 63/184 (34%), Gaps = 22/184 (11%)

Query: 280 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPG 339
           T   +P+   P    K P+P    PA T       EP P     P  T PK P    AP 
Sbjct: 413 TTPKEPTPTTP----KEPAPTTKEPAPTTP----KEPAPTAPKKPAPTTPKEP----APT 460

Query: 340 PFSEQASLLDLDFDPLPPVTSPVKAPTPSG-QSIPWDLWEPTESPAGSLPSGEPSAAEGT 398
              E A     +  P  P     K P P+  +S P    EP  +   S P+     +  T
Sbjct: 461 TPKEPAPTTTKEPSPTTP-----KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 515

Query: 399 FAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSS----LPAVVVET 454
                P+   EP P  P + +            +EP  T   + A ++     P    ET
Sbjct: 516 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 575

Query: 455 FPAT 458
            P T
Sbjct: 576 APTT 579



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 48/181 (26%), Positives = 67/181 (37%), Gaps = 15/181 (8%)

Query: 285 PSDNAPAKGNK-SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSE 343
           P + AP    K +P+ P+     TPE      PE     TP    P +P   E P P + 
Sbjct: 572 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP---EEPAPTTP 628

Query: 344 QASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSW 403
           +A+  +   +P P  T+P K P P+    P     PT +P  + P+     A  T     
Sbjct: 629 KAAAPNTPKEPAP--TTP-KEPAPTTPKEP----APT-TPKETAPTTPKGTAPTTLKEPA 680

Query: 404 PSQTAEPGPAQ--PAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNG 461
           P+   +P P +  P    E    T        P  TA +       P    E  P T  G
Sbjct: 681 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT-TPKEPAPTTPKEPAPTTPKG 739

Query: 462 T 462
           T
Sbjct: 740 T 740



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 48/202 (23%), Positives = 67/202 (33%), Gaps = 19/202 (9%)

Query: 280 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPS-QFEAP 338
           T   +P+         +P  P  +    P      EP P     P  T PK P+   + P
Sbjct: 374 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 433

Query: 339 GPFSEQASLLDLDFDPLP-------PVTSPVKAPTPSGQSIPWDLWEPTESPAGSLP--S 389
            P + +         P P       P T    APT + +  P    EP  +   S P  +
Sbjct: 434 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 493

Query: 390 GEPS-----AAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAAS 444
            EP+     +A  T     P+ T EP P  P E +            +EP  T   E A 
Sbjct: 494 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 553

Query: 445 SS----LPAVVVETFPATVNGT 462
           ++     P    E  P T   T
Sbjct: 554 TTTKKPAPTTPKEPAPTTPKET 575



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 46/178 (25%), Positives = 63/178 (35%), Gaps = 19/178 (10%)

Query: 285 PSDNAPAKGNK-SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSE 343
           P   AP    K +P+ P+     TPE      PE     TP A  P +P +   P P + 
Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE---PAPTTP 644

Query: 344 QASLLDLDFDPLP-------PVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSA-- 394
           +        +P P       P T    APT   +  P    +P         + EP++  
Sbjct: 645 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 704

Query: 395 ----AEGTFAVSWPSQTAEPGPAQPAE-ASEVAGGTQPAAGAQEPGETAASEAASSSL 447
               A  T   + P+   EP P  P E A     GT P    +EP  T   + A   L
Sbjct: 705 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT-LKEPAPTTPKKPAPKEL 761



 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 50/181 (27%), Positives = 69/181 (38%), Gaps = 24/181 (13%)

Query: 285 PSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGAT--PGATLPKS-PSQFEAPGP 340
           P + AP     +P+ P + +P  T E       EPA   T  P  T  KS P+  + P P
Sbjct: 337 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 396

Query: 341 FSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFA 400
            + +        +P P  T+P K PTP+    P +    T+ PA + P      A    A
Sbjct: 397 TTPKKPAPTTPKEPAP--TTP-KEPTPT---TPKEPAPTTKEPAPTTPKEPAPTAPKKPA 450

Query: 401 VSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAA---SSSLPAVVVETFPA 457
              P+   EP P  P E +            +EP  T   E A   + S P    E  P 
Sbjct: 451 ---PTTPKEPAPTTPKEPAPTT--------TKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 499

Query: 458 T 458
           T
Sbjct: 500 T 500



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 50/182 (27%), Positives = 69/182 (37%), Gaps = 26/182 (14%)

Query: 285 PSDNAPAKGNKSPSPPDGSPAAT----PEIRVNHEPEPAGGATPGATLPKSPSQF--EAP 338
           P + AP     +P+ P   PA T    P      EP P     P  T  K PS    + P
Sbjct: 423 PKEPAPTTKEPAPTTPK-EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 481

Query: 339 GPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEP----TESPAGSLPSGEPSA 394
            P + +++          P T+   APT + +S P    EP    T+ PA + P  EP  
Sbjct: 482 APTTTKSA----------PTTTKEPAPTTT-KSAPTTPKEPSPTTTKEPAPTTPK-EP-- 527

Query: 395 AEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVET 454
           A  T     P+   EP P  P E +            +EP  T   E A ++ P  +  T
Sbjct: 528 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT-PKKLTPT 586

Query: 455 FP 456
            P
Sbjct: 587 TP 588


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 50/189 (26%), Positives = 66/189 (34%), Gaps = 13/189 (6%)

Query: 282 KAQPSDNAP-AKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQF---EA 337
           K    D AP +K    P+P   +    P +    EP P     P +T PK P+      A
Sbjct: 315 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 374

Query: 338 PGPFSEQASLLDLDFDPLP----PVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPS 393
           P    E A          P    P T+   APT   +  P    EP  +   S P+    
Sbjct: 375 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 434

Query: 394 AAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSS----LPA 449
            A  T     P+   EP P  P E +      +PA   +EP  T   E A ++     P 
Sbjct: 435 PAPTTPKKPAPTTPKEPAPTTPKEPTPTT-PKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 493

Query: 450 VVVETFPAT 458
              E  P T
Sbjct: 494 TPKEPAPTT 502



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 47/184 (25%), Positives = 63/184 (34%), Gaps = 22/184 (11%)

Query: 280 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPG 339
           T   +P+   P    K P+P    PA T       EP P     P  T PK P    AP 
Sbjct: 454 TTPKEPTPTTP----KEPAPTTKEPAPTTP----KEPAPTAPKKPAPTTPKEP----APT 501

Query: 340 PFSEQASLLDLDFDPLPPVTSPVKAPTPSG-QSIPWDLWEPTESPAGSLPSGEPSAAEGT 398
              E A     +  P  P     K P P+  +S P    EP  +   S P+     +  T
Sbjct: 502 TPKEPAPTTTKEPSPTTP-----KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 556

Query: 399 FAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSS----LPAVVVET 454
                P+   EP P  P + +            +EP  T   + A ++     P    ET
Sbjct: 557 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 616

Query: 455 FPAT 458
            P T
Sbjct: 617 APTT 620



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 48/181 (26%), Positives = 67/181 (37%), Gaps = 15/181 (8%)

Query: 285 PSDNAPAKGNK-SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSE 343
           P + AP    K +P+ P+     TPE      PE     TP    P +P   E P P + 
Sbjct: 613 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP---EEPAPTTP 669

Query: 344 QASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSW 403
           +A+  +   +P P  T+P K P P+    P     PT +P  + P+     A  T     
Sbjct: 670 KAAAPNTPKEPAP--TTP-KEPAPTTPKEP----APT-TPKETAPTTPKGTAPTTLKEPA 721

Query: 404 PSQTAEPGPAQ--PAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNG 461
           P+   +P P +  P    E    T        P  TA +       P    E  P T  G
Sbjct: 722 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT-TPKEPAPTTPKEPAPTTPKG 780

Query: 462 T 462
           T
Sbjct: 781 T 781



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 48/202 (23%), Positives = 67/202 (33%), Gaps = 19/202 (9%)

Query: 280 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPS-QFEAP 338
           T   +P+         +P  P  +    P      EP P     P  T PK P+   + P
Sbjct: 415 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 474

Query: 339 GPFSEQASLLDLDFDPLP-------PVTSPVKAPTPSGQSIPWDLWEPTESPAGSLP--S 389
            P + +         P P       P T    APT + +  P    EP  +   S P  +
Sbjct: 475 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 534

Query: 390 GEPS-----AAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAAS 444
            EP+     +A  T     P+ T EP P  P E +            +EP  T   E A 
Sbjct: 535 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 594

Query: 445 SS----LPAVVVETFPATVNGT 462
           ++     P    E  P T   T
Sbjct: 595 TTTKKPAPTTPKEPAPTTPKET 616



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 46/178 (25%), Positives = 63/178 (35%), Gaps = 19/178 (10%)

Query: 285 PSDNAPAKGNK-SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSE 343
           P   AP    K +P+ P+     TPE      PE     TP A  P +P +   P P + 
Sbjct: 629 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE---PAPTTP 685

Query: 344 QASLLDLDFDPLP-------PVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSA-- 394
           +        +P P       P T    APT   +  P    +P         + EP++  
Sbjct: 686 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 745

Query: 395 ----AEGTFAVSWPSQTAEPGPAQPAE-ASEVAGGTQPAAGAQEPGETAASEAASSSL 447
               A  T   + P+   EP P  P E A     GT P    +EP  T   + A   L
Sbjct: 746 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT-LKEPAPTTPKKPAPKEL 802



 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 50/181 (27%), Positives = 69/181 (38%), Gaps = 24/181 (13%)

Query: 285 PSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGAT--PGATLPKS-PSQFEAPGP 340
           P + AP     +P+ P + +P  T E       EPA   T  P  T  KS P+  + P P
Sbjct: 378 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 437

Query: 341 FSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFA 400
            + +        +P P  T+P K PTP+    P +    T+ PA + P      A    A
Sbjct: 438 TTPKKPAPTTPKEPAP--TTP-KEPTPT---TPKEPAPTTKEPAPTTPKEPAPTAPKKPA 491

Query: 401 VSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAA---SSSLPAVVVETFPA 457
              P+   EP P  P E +            +EP  T   E A   + S P    E  P 
Sbjct: 492 ---PTTPKEPAPTTPKEPAPTT--------TKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 540

Query: 458 T 458
           T
Sbjct: 541 T 541



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 50/182 (27%), Positives = 69/182 (37%), Gaps = 26/182 (14%)

Query: 285 PSDNAPAKGNKSPSPPDGSPAAT----PEIRVNHEPEPAGGATPGATLPKSPSQF--EAP 338
           P + AP     +P+ P   PA T    P      EP P     P  T  K PS    + P
Sbjct: 464 PKEPAPTTKEPAPTTPK-EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 522

Query: 339 GPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEP----TESPAGSLPSGEPSA 394
            P + +++          P T+   APT + +S P    EP    T+ PA + P  EP  
Sbjct: 523 APTTTKSA----------PTTTKEPAPTTT-KSAPTTPKEPSPTTTKEPAPTTPK-EP-- 568

Query: 395 AEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVET 454
           A  T     P+   EP P  P E +            +EP  T   E A ++ P  +  T
Sbjct: 569 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT-PKKLTPT 627

Query: 455 FP 456
            P
Sbjct: 628 TP 629


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
           sapiens]
          Length = 2524

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 58/221 (26%), Positives = 88/221 (39%), Gaps = 35/221 (15%)

Query: 245 IAGLEENFHKEMSKLNQNLNDVLVG-----LEKQHGSNTFTVKAQPSDNAPAKGNKSPSP 299
           ++G EE   +E   L+ + N+V  G         + S+T ++ +  ++ A   G   P P
Sbjct: 710 VSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKP 769

Query: 300 P-----DGSPAATP-----EIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQASLLD 349
           P     DG P   P     +I    EP PA  AT   T P +P    AP P   +    +
Sbjct: 770 PATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEE-KE 828

Query: 350 LDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAE 409
            +    PPV    +   P+ + +  D  +          + EP  +E T       + AE
Sbjct: 829 EETAAAPPVEEGEEQKPPAAEELAVDTGK----------AEEPVKSECT-------EEAE 871

Query: 410 PGPA--QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLP 448
            GPA  + AEA+E        A  +E G   A+ A SS  P
Sbjct: 872 EGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAP 912


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 49/202 (24%), Positives = 74/202 (36%), Gaps = 17/202 (8%)

Query: 278  TFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSP-SQFE 336
            T    A P+   P     +  PP+   +    +    EP     A P    P SP +   
Sbjct: 1014 TSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1073

Query: 337  APGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAE 396
             P   +  A+ +    +P  P  +      P+  +      E   SPA ++P+ E  A+ 
Sbjct: 1074 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASP 1133

Query: 397  GTFAVSWPSQTAEPGPAQPAEASEVAG---------GTQPAAGAQEPGETAASEAASSSL 447
               AV  P + A P PA P      +             PAA    P E+A+  A  ++L
Sbjct: 1134 AA-AVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATL 1192

Query: 448  -----PAVVVETFPATVNGTVE 464
                 PA  V T PA +  T+E
Sbjct: 1193 EEPTSPAASVPT-PAAMVATLE 1213



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 54/180 (30%), Positives = 70/180 (38%), Gaps = 11/180 (6%)

Query: 289  APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQASLL 348
            +PA    +P  P    AA P      EP     A P    P SP+    P P  E  S  
Sbjct: 1054 SPAAAVPTPEEPTSPAAAVP---TPEEPTSPAAAVPTPEEPTSPAA-AVPTP-EEPTSPA 1108

Query: 349  DLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTES---PAGSLPSGEPSAAEGTFAVSWPS 405
                 P  P +     PTP   + P       E    PA ++P+ E SA+    AV  P 
Sbjct: 1109 AAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESAS-AAVAVPTPE 1167

Query: 406  QTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVE-TFPATVNGTVE 464
            ++A P  A P  A E A      A  +EP   AAS    +++ A + E T PA    T E
Sbjct: 1168 ESASPAAAVPTPA-ESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSE 1226



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 66/230 (28%), Positives = 82/230 (35%), Gaps = 36/230 (15%)

Query: 266  VLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPG 325
            V V   ++  S    V       +PA    +P  P    AA P      EP     A P 
Sbjct: 992  VRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPP---PEEPTSPAAAVPT 1048

Query: 326  ATLPKSPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAG 385
               P SP+    P P  E  S       P  P +     PTP          EPT SPA 
Sbjct: 1049 PEEPTSPAA-AVPTP-EEPTSPAAAVPTPEEPTSPAAAVPTPE---------EPT-SPAA 1096

Query: 386  SLPSGE----PSAAEGT--------FAVSWPSQTAEPG--------PAQPAEASEVAGGT 425
            ++P+ E    P+AA  T         AV  P + A P         PA PA A      +
Sbjct: 1097 AVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEES 1156

Query: 426  QPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLP 475
              AA A    E +AS AA+   PA    +F A V    E  S A  +  P
Sbjct: 1157 ASAAVAVPTPEESASPAAAVPTPAESA-SFAAVVATLEEPTSPAASVPTP 1205



 Score = 33.9 bits (76), Expect = 0.40
 Identities = 44/171 (25%), Positives = 61/171 (35%), Gaps = 26/171 (15%)

Query: 298  SPPDGSPAATPEIRVNHEPEPAGGATPGA----TLPKSPSQFEAPGPFSEQASLLDLDFD 353
            SP + +PA    I        AG +   A    T+P +       GP +   ++      
Sbjct: 928  SPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTV----HA 983

Query: 354  PLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPA 413
            P  P T+ V+  TP          E   SPA ++P+ E   +    AV  P +   P  A
Sbjct: 984  PEEPDTAAVRVSTP----------EEPASPAAAVPTPEEPTSPAA-AVPTPEEPTSPAAA 1032

Query: 414  QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVE 464
             P         T PAA    P E  +  AA   +P     T PA    T E
Sbjct: 1033 VPPPEEP----TSPAAAVPTPEEPTSPAAA---VPTPEEPTSPAAAVPTPE 1076


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 46/182 (25%), Positives = 72/182 (39%), Gaps = 32/182 (17%)

Query: 280 TVKAQPSDNAPAKGNKSPS---PPDGSPAATPEIRVNHEP-EPAGGATPGATL------- 328
           +VKA  S+  P K +  P    PP  S   +P +  + EP  P+  A+P +         
Sbjct: 217 SVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSP 276

Query: 329 -PKSPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSL 387
            P+ PS  E+P P+    ++      P P V+     P P G   PW             
Sbjct: 277 EPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPW------------- 323

Query: 388 PSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSL 447
               PSA+ G +  + P+ +  PGP +P  +        P      P  ++AS  +SS  
Sbjct: 324 -KSNPSASSGPWKPAKPAPSVSPGPWKPIPS------VSPGPWKPTPSVSSASWKSSSVS 376

Query: 448 PA 449
           P+
Sbjct: 377 PS 378



 Score = 37.4 bits (85), Expect = 0.036
 Identities = 52/215 (24%), Positives = 77/215 (35%), Gaps = 38/215 (17%)

Query: 280 TVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLP---------- 329
           T   +P   +P++   SP P    PA +PE R      PA   +PG+  P          
Sbjct: 273 TTSPEPRKPSPSE---SPEPWKPFPAVSPEPR-----RPAPAVSPGSWKPGPPGSPRPWK 324

Query: 330 KSPSQFEAPG-PFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPW-------DLWEPTE 381
            +PS    P  P     S+    + P+P V+     PTPS  S  W         W+   
Sbjct: 325 SNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPP 384

Query: 382 SPAGSLPSGEPSAAEGTFAVS---WPS------QTAEPGPAQPAEASEVAGGTQPAAGAQ 432
           +   S  SG P   +    +S   W +      +  +PGP    E    AG  +    + 
Sbjct: 385 ASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSG 444

Query: 433 EPGETAASEAASSSLPAVVVETFPATVNGTVEGGS 467
            P     S     + PA +   FP +   +  GGS
Sbjct: 445 SPDLWKLSPDQRKTSPASL--DFPESQKSS-RGGS 476



 Score = 33.5 bits (75), Expect = 0.52
 Identities = 51/190 (26%), Positives = 77/190 (40%), Gaps = 44/190 (23%)

Query: 282 KAQPSDNAPAKGNKSPSPPDG-SPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGP 340
           K  PS ++ +  + S SP    SP A+PE   +  PE    A    TL  SP  ++A  P
Sbjct: 360 KPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAP---TL--SPEHWKAVPP 414

Query: 341 FSEQASLLDLDFDPLPPVTSPVKAPT-------PSGQSIPWDLW--EPTESPAG------ 385
            S +         P PP++  +++P        PSG    W L   +   SPA       
Sbjct: 415 VSPELR------KPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPES 468

Query: 386 --SLPSGEPSAAEGTFAVSWPS----QTAEPGPAQPAEASEVAG---------GTQPAAG 430
             S   G P   + +F +        +T +PGP+ P+E+ + A           T+P   
Sbjct: 469 QKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKP 528

Query: 431 A--QEPGETA 438
           A   EP +TA
Sbjct: 529 ALFPEPAKTA 538



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 44/180 (24%), Positives = 60/180 (33%), Gaps = 26/180 (14%)

Query: 290 PAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQASLLD 349
           P K     SP   +P  +PE     +P       P  ++P   SQ  AP P         
Sbjct: 156 PQKPGSVVSPELQTPLPSPE---PSKPASVSSPEPPKSVPVCESQKLAPVP--------- 203

Query: 350 LDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPS--GEPSAAEGTFAVSWPSQT 407
               P P   +PV     S +S+   L  P        P   G PSA+    +   P   
Sbjct: 204 ---SPEPQKPAPV-----SPESVKATLSNPKPQKQSHFPETLGPPSAS----SPESPVLA 251

Query: 408 AEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGS 467
           A P P  P+ A+           + EP + + SE+     P   V   P      V  GS
Sbjct: 252 ASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGS 311


>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
          Length = 780

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 58/218 (26%), Positives = 79/218 (36%), Gaps = 35/218 (16%)

Query: 266 VLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPG 325
           V+  ++  HG  + T  +  + +      K   P    P +    +    P P GGA   
Sbjct: 228 VVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQ 287

Query: 326 ATLPKSPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTE---- 381
           ++ P  P    A GP    A+       P  P     +   P GQ++P     PT     
Sbjct: 288 SSAPLPPFPGAATGPQPMMAAA-----QPSQP-----QGAGPGGQTLP-----PTNVTLA 332

Query: 382 SPAGSLPSGEPSAAEGTFAVSWPSQTAEPG---------PAQPAEASEVAGGTQPAAGAQ 432
            PA SLP  +P  A G  A   P Q A P          P QP+  SE     Q  AG Q
Sbjct: 333 QPAMSLPP-QPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYL--QQHVAGLQ 389

Query: 433 EPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAG 470
            P     S   +++ PA    T P    GT +  S  G
Sbjct: 390 PPSPAQPSSTGAAASPATAA-TLPV---GTGQNASSVG 423


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 57/181 (31%), Positives = 65/181 (35%), Gaps = 29/181 (16%)

Query: 283  AQPSDN-APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPF 341
            A PS   AP     +P  P G PA          P P G  TP A  P SP     P   
Sbjct: 955  ATPSPKWAPTPPAATPPSPKGGPAT---------PSPKGAPTPPAATPPSPKG--GPATP 1003

Query: 342  SEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGS-----LPSGEPSAAE 396
            S + +       P  P  SP   P P G S P     P  SP GS     LP G P+   
Sbjct: 1004 SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPP--SPKGSPAATPLPKGAPT--- 1058

Query: 397  GTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEP-GETAASEAASSSLPAVVVETF 455
             T A + PS   + GPA P   S     T PAA    P G  A      + +P       
Sbjct: 1059 -TPAATLPS--PKGGPATP---SLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS 1112

Query: 456  P 456
            P
Sbjct: 1113 P 1113



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 53/184 (28%), Positives = 68/184 (36%), Gaps = 22/184 (11%)

Query: 278  TFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEA 337
            T   K  P+  AP +    P+    SP  TP I    E      ATP +    SP     
Sbjct: 1532 TLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAP----ATPSSKEASSPPAV-T 1586

Query: 338  PGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEG 397
            P  +    S  +L   P     SP +APTP   + P     P + PA   P G P++   
Sbjct: 1587 PSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPP----SPEKGPATPAPKGTPTSPPV 1642

Query: 398  TFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEP---GETAASEA----ASSSLPAV 450
            T     PS + +  P  PA  +   G T P A    P   G TA  E     A  S P +
Sbjct: 1643 T-----PS-SLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPII 1696

Query: 451  VVET 454
               T
Sbjct: 1697 TAPT 1700



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 49/180 (27%), Positives = 59/180 (32%), Gaps = 24/180 (13%)

Query: 289  APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEA-PGPFSEQASL 347
            APA    S SP        P+  +   P P G  TP A  P SP    A P P       
Sbjct: 908  APALSMTSSSPKKARATPAPK-GIPASPSPKGAPTPPAATPPSPKGGPATPSP------- 959

Query: 348  LDLDFDPLPPVTSPVK------APTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAV 401
                + P PP  +P         P+P G   P     P  SP G   +  P  A    AV
Sbjct: 960  ---KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPP--SPKGGPATPSPKGAPTPPAV 1014

Query: 402  SWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNG 461
            + PS    P     A        T PAA    P  + A+       P     T P+   G
Sbjct: 1015 TPPSPKGSPA----ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG 1070



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 47/168 (27%), Positives = 65/168 (38%), Gaps = 17/168 (10%)

Query: 285 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQ 344
           P ++   +G+K       SP  TP       P P G  TP A  P SP     P   +  
Sbjct: 837 PENSLSFQGSKDSPATTHSP--TP-------PSPKGAPTPSAVTPLSPKGVTLPPKETPT 887

Query: 345 ASLLDLDFDPLPPVT-SPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSW 403
            S+++L F    P T +P +AP  S  S       P ++ A   P G P++     A + 
Sbjct: 888 PSVVNLPFPKEGPATPAPKQAPALSMTSS-----SPKKARATPAPKGIPASPSPKGAPTP 942

Query: 404 PSQTAEPGPAQPAEASEVAGGTQPAAGAQEP--GETAASEAASSSLPA 449
           P+ T       PA  S     T PAA    P  G    S   + + PA
Sbjct: 943 PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPA 990



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 52/190 (27%), Positives = 62/190 (32%), Gaps = 39/190 (20%)

Query: 285  PSDNAPA-KGNKSPSPPDGSP---AATPEIRVNHEPEPAGG----------ATPGATLPK 330
            P+   P+ KG  +  PP G+P   AATP       P P GG           TP AT P 
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATP-------PSPKGGLATPPPKGAPTTPAATPPS 1181

Query: 331  SPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAP----TPSGQSIPWDLWEPTESPAGS 386
                   P P             P  P  +P        TPS +  P        SP G 
Sbjct: 1182 PKGGLATPSPKGA----------PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1231

Query: 387  LPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSS 446
            L +  P  A  T A + PS    P    P  A      T P+      G  A      + 
Sbjct: 1232 LATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSL----KGGLATPPHKGAP 1287

Query: 447  LPAVVVETFP 456
             PAVV    P
Sbjct: 1288 NPAVVTPPSP 1297



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 59/210 (28%), Positives = 76/210 (36%), Gaps = 56/210 (26%)

Query: 285  PSDNAPA-KGNKSPSPPDGSP---AATPEIRVNHEPEPAGGATPGATLPKS------PSQ 334
            P+   P+ KG+    PP G+P   A TP       P P G  T  AT P S      PS 
Sbjct: 1313 PAATPPSPKGSPGTPPPKGAPTPPAVTP-------PSPKGTPTLPATTPSSKGGPTTPSS 1365

Query: 335  FEAPGPFSEQAS-----------------LLDLDFDPLPPVT---SPVKAP----TPSGQ 370
             E P P +   S                 +     DP  P     SP KAP    T  G 
Sbjct: 1366 KEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGA 1425

Query: 371  SIP--WDLWEPT-------ESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEV 421
            + P   DL  P        ++PA S P G P+        + P+ T  P P +P    +V
Sbjct: 1426 ATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT-PPSPKEPPAPKQV 1484

Query: 422  AGGTQPAAGAQEPGETAASEAASSSLPAVV 451
            A  + P      P    A      +LPAV+
Sbjct: 1485 ATSSSPKKAPATPAPMGA-----PTLPAVI 1509



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 55/213 (25%), Positives = 70/213 (32%), Gaps = 55/213 (25%)

Query: 283  AQPSDN-APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPF 341
            A PS   AP     +P  P GSPAATP         P G +TP A  P SP    A  P 
Sbjct: 1001 ATPSPKGAPTPPAVTPPSPKGSPAATPF--------PKGASTPPAATPPSPKGSPAATPL 1052

Query: 342  SEQASLL---------------DLDFDPLPPVTSPVK------APTPSGQSIPWDLWEPT 380
             + A                   L   P PP  +P         P+P G  +P     P+
Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS 1112

Query: 381  E---------------------SPAGSLPSGEPSAAEGTFAVSWPSQ---TAEPGPAQPA 416
                                  SP G L +  P  A  T A + PS     A P P + A
Sbjct: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP-PPKGA 1171

Query: 417  EASEVAGGTQPAAGAQEPGETAASEAASSSLPA 449
              +  A    P  G   P    A    +++ P+
Sbjct: 1172 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1204



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 48/203 (23%), Positives = 73/203 (35%), Gaps = 38/203 (18%)

Query: 280  TVKAQPSDNAPAKGNKSPS------------PPDGSPAATPEIRVNHEPE-------PAG 320
            ++K  P+ +AP  G  +PS            P    P A  ++  +  P+       P G
Sbjct: 1442 SLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG 1501

Query: 321  GATPGATLPKSPSQFEAP-----GPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWD 375
              T  A +P SP +  A       P +  A+LL       P   +P +A  P   ++P  
Sbjct: 1502 APTLPAVIPSSPKEVPATPSSRRDPIAPTATLLS---KKTPATLAPKEALIPPAMTVP-- 1556

Query: 376  LWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPG 435
               P ++PA   P   P+      A S P+ T       P+    +     PA  +  P 
Sbjct: 1557 --SPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELL---IPPAVTSPSPK 1611

Query: 436  ETAASEAASSSLPAVVVETFPAT 458
            E     A +   P    E  PAT
Sbjct: 1612 EAPTPPAVTPPSP----EKGPAT 1630



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 52/201 (25%), Positives = 64/201 (31%), Gaps = 21/201 (10%)

Query: 275  GSNTFTVKAQPSDNAPAKGNKSPSPPDG--SPAATPEIRVNH--EPEPAGGATPGATLPK 330
            G+ T      PS   P  G  +PSP     +PAATP         P P G  T  A  P 
Sbjct: 1193 GAPTTPAATPPS---PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1249

Query: 331  SPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAP----TPSGQSIPWDLWEPTESPAGS 386
            SP    A  P             P PP  +P        TP  +  P        SP G 
Sbjct: 1250 SPKGGPATPPPKGA---------PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG 1300

Query: 387  LPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPA-AGAQEPGETAASEAASS 445
              +  P  A    A + PS    PG   P  A      T P+  G      T  S     
Sbjct: 1301 PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGP 1360

Query: 446  SLPAVVVETFPATVNGTVEGG 466
            + P+      P     + +GG
Sbjct: 1361 TTPSSKEGPTPPAATPSHKGG 1381



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 46/192 (23%), Positives = 60/192 (31%), Gaps = 28/192 (14%)

Query: 275  GSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGG----------ATP 324
            G  T ++K  P+  A    +    P   SP   P       P P GG           TP
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTP 1129

Query: 325  GATLPKSPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVK----APTPSGQSIPWDLWEPT 380
             AT P        P P             P  P  +P        TP  +  P       
Sbjct: 1130 AATPPSPKGGLATPPPKGA----------PTTPAATPPSPKGGLATPPPKGAPTTPAATP 1179

Query: 381  ESPAGSLPSGEPSAAEGTFAVSWPSQ---TAEPGPAQPAEASEVAGGTQPAAGAQEPGET 437
             SP G L +  P  A  T A + PS     A P P + A  +  A    P  G   P   
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP-KGAPTTPAATPPSPKGGLATPSPK 1238

Query: 438  AASEAASSSLPA 449
             A    +++ P+
Sbjct: 1239 GAPTTPAATPPS 1250


>gi|239742468 PREDICTED: double homeobox, 4-like [Homo sapiens]
          Length = 485

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 54/198 (27%), Positives = 74/198 (37%), Gaps = 45/198 (22%)

Query: 284 QPSDNAPAKGNKSPSPPDGSPA----ATPEIRVNHEPEPAGGATPGATLP-KSPSQFEAP 338
           QPS  APA+G   P+P  G  A    A P+  ++H   P     PG +   + P +   P
Sbjct: 280 QPSQAAPAEGVSQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDRDPQRDGLP 339

Query: 339 GPFSEQASLLDLDFDPLPPVTSP----VKAPTPSGQSIPWDLW--------EPTESPAGS 386
           GP +           P P    P    V AP P+ Q  PW  W           E  AG+
Sbjct: 340 GPCAVA--------QPGPAQAGPQGQGVLAP-PTSQGSPWWGWGRGPQVAGAAWEPQAGA 390

Query: 387 LPSGEPSAAEGTFAVSWPSQTAEPGPAQ----PAEASEVAGG---------------TQP 427
            P  +P+  + + +         P P+Q    PA  S +  G                QP
Sbjct: 391 APPPQPAPPDASASARQGQMQGIPAPSQALQEPAPWSALPCGLLLDELLASPEFLQQAQP 450

Query: 428 AAGAQEPGETAASEAASS 445
               + PGE  ASE A+S
Sbjct: 451 LLETEAPGELEASEEAAS 468


>gi|194272172 double homeobox, 4 [Homo sapiens]
          Length = 485

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 54/198 (27%), Positives = 74/198 (37%), Gaps = 45/198 (22%)

Query: 284 QPSDNAPAKGNKSPSPPDGSPA----ATPEIRVNHEPEPAGGATPGATLP-KSPSQFEAP 338
           QPS  APA+G   P+P  G  A    A P+  ++H   P     PG +   + P +   P
Sbjct: 280 QPSQAAPAEGVSQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDRDPQRDGLP 339

Query: 339 GPFSEQASLLDLDFDPLPPVTSP----VKAPTPSGQSIPWDLW--------EPTESPAGS 386
           GP +           P P    P    V AP P+ Q  PW  W           E  AG+
Sbjct: 340 GPCAVA--------QPGPAQAGPQGQGVLAP-PTSQGSPWWGWGRGPQVAGAAWEPQAGA 390

Query: 387 LPSGEPSAAEGTFAVSWPSQTAEPGPAQ----PAEASEVAGG---------------TQP 427
            P  +P+  + + +         P P+Q    PA  S +  G                QP
Sbjct: 391 APPPQPAPPDASASARQGQMQGIPAPSQALQEPAPWSALPCGLLLDELLASPEFLQQAQP 450

Query: 428 AAGAQEPGETAASEAASS 445
               + PGE  ASE A+S
Sbjct: 451 LLETEAPGELEASEEAAS 468


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.128    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,450,134
Number of Sequences: 37866
Number of extensions: 1437995
Number of successful extensions: 10167
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 121
Number of HSP's successfully gapped in prelim test: 1100
Number of HSP's that attempted gapping in prelim test: 7320
Number of HSP's gapped (non-prelim): 3159
length of query: 550
length of database: 18,247,518
effective HSP length: 107
effective length of query: 443
effective length of database: 14,195,856
effective search space: 6288764208
effective search space used: 6288764208
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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