Guide to the Human Genome
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Search of human proteins with 21536367

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21536367 TBP-associated factor 1C isoform 2 [Homo sapiens]
         (775 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21536367 TBP-associated factor 1C isoform 2 [Homo sapiens]        1598   0.0  
gi|21536369 TBP-associated factor 1C isoform 1 [Homo sapiens]        1578   0.0  
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap...    44   6e-04
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap...    44   6e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    43   0.001
gi|239753975 PREDICTED: hypothetical protein [Homo sapiens]            42   0.003
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    41   0.005
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       41   0.005
gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo...    40   0.006
gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo ...    40   0.006
gi|239755589 PREDICTED: hypothetical protein [Homo sapiens]            40   0.008
gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo ...    39   0.014
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       39   0.018
gi|116284392 mucin 2 precursor [Homo sapiens]                          39   0.024
gi|153792074 proline rich 12 [Homo sapiens]                            39   0.024
gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]       38   0.031
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap...    38   0.031
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap...    38   0.031
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         38   0.041
gi|188536004 zinc finger protein 469 [Homo sapiens]                    37   0.053
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              37   0.053
gi|54860079 nadrin isoform 1 [Homo sapiens]                            37   0.053
gi|54860105 nadrin isoform 2 [Homo sapiens]                            37   0.053
gi|89941470 ankyrin repeat domain 34 [Homo sapiens]                    37   0.053
gi|239582735 radial spoke head 4 homolog A isoform 2 [Homo sapiens]    37   0.070
gi|58219006 radial spoke head 4 homolog A isoform 1 [Homo sapiens]     37   0.070
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    37   0.070
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    37   0.070
gi|24308394 hypothetical protein LOC140893 [Homo sapiens]              37   0.070
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        37   0.091

>gi|21536367 TBP-associated factor 1C isoform 2 [Homo sapiens]
          Length = 775

 Score = 1598 bits (4139), Expect = 0.0
 Identities = 775/775 (100%), Positives = 775/775 (100%)

Query: 1   MLPPLIDPWDPGLTARDLLFRGGCRYRKRPRVVLDVTEQISRFLLDHGDVAFAPLGKLML 60
           MLPPLIDPWDPGLTARDLLFRGGCRYRKRPRVVLDVTEQISRFLLDHGDVAFAPLGKLML
Sbjct: 1   MLPPLIDPWDPGLTARDLLFRGGCRYRKRPRVVLDVTEQISRFLLDHGDVAFAPLGKLML 60

Query: 61  ENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGPILGTSVA 120
           ENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGPILGTSVA
Sbjct: 61  ENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGPILGTSVA 120

Query: 121 SHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRLHFQEVVL 180
           SHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRLHFQEVVL
Sbjct: 121 SHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRLHFQEVVL 180

Query: 181 TPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGETLLAVRSDYHCAVWKFGKQWQPTLLQAM 240
           TPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGETLLAVRSDYHCAVWKFGKQWQPTLLQAM
Sbjct: 181 TPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGETLLAVRSDYHCAVWKFGKQWQPTLLQAM 240

Query: 241 QVEKGATGISLSPHLPGELAICSRSGAVCLWSPEDGLRQIYRDPETLVFRDSSSWRWADF 300
           QVEKGATGISLSPHLPGELAICSRSGAVCLWSPEDGLRQIYRDPETLVFRDSSSWRWADF
Sbjct: 241 QVEKGATGISLSPHLPGELAICSRSGAVCLWSPEDGLRQIYRDPETLVFRDSSSWRWADF 300

Query: 301 TAHPRVLTVGDRTGVKMLDTQGPPGCGLLLFRLGAEASCQKGERVLLTQYLGHSSPKCLP 360
           TAHPRVLTVGDRTGVKMLDTQGPPGCGLLLFRLGAEASCQKGERVLLTQYLGHSSPKCLP
Sbjct: 301 TAHPRVLTVGDRTGVKMLDTQGPPGCGLLLFRLGAEASCQKGERVLLTQYLGHSSPKCLP 360

Query: 361 PTLHLVCTQFSLYLVDERLPLVPMLKWNHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQ 420
           PTLHLVCTQFSLYLVDERLPLVPMLKWNHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQ
Sbjct: 361 PTLHLVCTQFSLYLVDERLPLVPMLKWNHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQ 420

Query: 421 LQLLHLAEGASVPRLAGPPQSLPSRIDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPP 480
           LQLLHLAEGASVPRLAGPPQSLPSRIDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPP
Sbjct: 421 LQLLHLAEGASVPRLAGPPQSLPSRIDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPP 480

Query: 481 LPSAPTPGLVLFQLSAAGDVFYQQLRPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTA 540
           LPSAPTPGLVLFQLSAAGDVFYQQLRPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTA
Sbjct: 481 LPSAPTPGLVLFQLSAAGDVFYQQLRPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTA 540

Query: 541 GCSQWLKALLKVPLAPPVWTAPTFTHRQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQ 600
           GCSQWLKALLKVPLAPPVWTAPTFTHRQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQ
Sbjct: 541 GCSQWLKALLKVPLAPPVWTAPTFTHRQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQ 600

Query: 601 RDLGSLPAAEPPPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRT 660
           RDLGSLPAAEPPPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRT
Sbjct: 601 RDLGSLPAAEPPPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRT 660

Query: 661 QLSSSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQM 720
           QLSSSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQM
Sbjct: 661 QLSSSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQM 720

Query: 721 LRDYMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSSQPLRKKPRMGF 775
           LRDYMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSSQPLRKKPRMGF
Sbjct: 721 LRDYMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSSQPLRKKPRMGF 775


>gi|21536369 TBP-associated factor 1C isoform 1 [Homo sapiens]
          Length = 869

 Score = 1578 bits (4086), Expect = 0.0
 Identities = 774/802 (96%), Positives = 775/802 (96%), Gaps = 27/802 (3%)

Query: 1   MLPPLIDPWDPGLTARDLLFRGGCRYRKRPRVVLDVTEQISRFLLDHGDVAFAPLGKLML 60
           MLPPLIDPWDPGLTARDLLFRGGCRYRKRPRVVLDVTEQISRFLLDHGDVAFAPLGKLML
Sbjct: 68  MLPPLIDPWDPGLTARDLLFRGGCRYRKRPRVVLDVTEQISRFLLDHGDVAFAPLGKLML 127

Query: 61  ENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGPILGTSVA 120
           ENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGPILGTSVA
Sbjct: 128 ENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGPILGTSVA 187

Query: 121 SHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRLHFQEVVL 180
           SHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRLHFQEVVL
Sbjct: 188 SHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRLHFQEVVL 247

Query: 181 TPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGET--------------------------L 214
           TPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGE+                          L
Sbjct: 248 TPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGESKALIYTFLPHWLTCYLTPGPFHPSSAL 307

Query: 215 LAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSGAVCLWSPE 274
           LAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSGAVCLWSPE
Sbjct: 308 LAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSGAVCLWSPE 367

Query: 275 DGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGCGLLLFRLG 334
           DGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGCGLLLFRLG
Sbjct: 368 DGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGCGLLLFRLG 427

Query: 335 AEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLKWNHGLPSP 394
           AEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLKWNHGLPSP
Sbjct: 428 AEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLKWNHGLPSP 487

Query: 395 LLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLA-EGASVPRLAGPPQSLPSRIDSLPAFP 453
           LLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLA EGASVPRLAGPPQSLPSRIDSLPAFP
Sbjct: 488 LLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLAGEGASVPRLAGPPQSLPSRIDSLPAFP 547

Query: 454 LLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQLRPQVDSSL 513
           LLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQLRPQVDSSL
Sbjct: 548 LLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQLRPQVDSSL 607

Query: 514 RRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTHRQMLGST 573
           RRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTHRQMLGST
Sbjct: 608 RRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTHRQMLGST 667

Query: 574 ELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSERLGEAWAG 633
           ELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSERLGEAWAG
Sbjct: 668 ELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSERLGEAWAG 727

Query: 634 RGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALP 693
           RGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALP
Sbjct: 728 RGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALP 787

Query: 694 LPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATR 753
           LPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATR
Sbjct: 788 LPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATR 847

Query: 754 SQQHTPVLSSSQPLRKKPRMGF 775
           SQQHTPVLSSSQPLRKKPRMGF
Sbjct: 848 SQQHTPVLSSSQPLRKKPRMGF 869


>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo
           sapiens]
          Length = 1758

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 46/166 (27%), Positives = 61/166 (36%), Gaps = 26/166 (15%)

Query: 579 EEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSERLGEAWAGRGAAW 638
           EE+G ++ VL      GQ LL   L  +P   P              R+  A  G G   
Sbjct: 460 EEKGYQVPVLGTPSLLGQSLLHGQL--IPTTGPV-------------RINTARPGGGRPG 504

Query: 639 WERQQ--GRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALPLPP 696
           WE     G    P +Q RR +R    S +     H + S+ T  P  P  P    +P PP
Sbjct: 505 WEHSNKLGYLVSPPQQIRRGERSCYRSINRGRH-HSERSQRTQGPSLPATPVFVPVPPPP 563

Query: 697 TTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPP 742
             PP     P     GVP  Q      +  + PP +  P   + PP
Sbjct: 564 LYPPPPHTLP--LPPGVPPPQ------FSPQFPPGQPPPAGYSVPP 601


>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo
           sapiens]
          Length = 1792

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 46/166 (27%), Positives = 61/166 (36%), Gaps = 26/166 (15%)

Query: 579 EEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSERLGEAWAGRGAAW 638
           EE+G ++ VL      GQ LL   L  +P   P              R+  A  G G   
Sbjct: 460 EEKGYQVPVLGTPSLLGQSLLHGQL--IPTTGPV-------------RINTARPGGGRPG 504

Query: 639 WERQQ--GRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALPLPP 696
           WE     G    P +Q RR +R    S +     H + S+ T  P  P  P    +P PP
Sbjct: 505 WEHSNKLGYLVSPPQQIRRGERSCYRSINRGRH-HSERSQRTQGPSLPATPVFVPVPPPP 563

Query: 697 TTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPP 742
             PP     P     GVP  Q      +  + PP +  P   + PP
Sbjct: 564 LYPPPPHTLP--LPPGVPPPQ------FSPQFPPGQPPPAGYSVPP 601


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 52/175 (29%), Positives = 64/175 (36%), Gaps = 25/175 (14%)

Query: 607 PAAEPPPAPESGLEDKLSERLGE--------AWAGRGAAWWERQQGRTSEP---GRQTRR 655
           PAA   P+   GL+   S  L          A +G  A    R     S+P   G Q  R
Sbjct: 213 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 272

Query: 656 PK-----RRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPA-DALPLPPTTPPSQELTP--- 706
           P      R+    +   LS     +   S+P SP  PP+   LP PP TPPSQ  T    
Sbjct: 273 PPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGS 332

Query: 707 ---DACAQGVPSEQRQMLRDYMAKLPPQRDTP--GCATTPPHSQASSVRATRSQQ 756
               A    +PS     L     + PP    P      +PP S   S  AT S Q
Sbjct: 333 PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ 387



 Score = 32.3 bits (72), Expect = 1.7
 Identities = 33/102 (32%), Positives = 40/102 (39%), Gaps = 10/102 (9%)

Query: 672 VDPSEDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLP-P 730
           V PS   S P SP   P      PP  PP     P   A+  P     +    +  LP P
Sbjct: 442 VPPSPPASPPMSPSATP------PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP 495

Query: 731 QRDTPGCAT-TPPHSQASSVRATRSQQHTPVLSSSQPLRKKP 771
               PG A  +P  S   S  AT   Q  PVL++  PL + P
Sbjct: 496 PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA--PLLQVP 535


>gi|239753975 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 389

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 31/98 (31%), Positives = 43/98 (43%), Gaps = 4/98 (4%)

Query: 673 DPSEDTSSPHSPEWPPADALPLPPT--TPPSQELTPDACAQGVPSEQRQMLRDYMAKLPP 730
           DP+   SSPH+P  PP  A+   P+  TP S+ L P +  +G P       R+  A  P 
Sbjct: 107 DPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPF 166

Query: 731 QRDTPGCATTPPHSQASSVRATRSQQHTPVLSSSQPLR 768
           +   P  +  PP  Q  S R        P   S +P+R
Sbjct: 167 RWGDP-FSPAPPRPQPPS-RPAAQPPSRPAFRSPRPVR 202


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 95/368 (25%), Positives = 129/368 (35%), Gaps = 76/368 (20%)

Query: 438 PPQSLPSRIDSLPAF------PLLEPKIQWRLQERLKAP---TIGLAAVVPPLPSAPTPG 488
           PPQ  P R D+ PA       PL  P         +  P      L A +PP P   TP 
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATP- 340

Query: 489 LVLFQLSAAGDVFYQQLRPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKA 548
           L L   S +     Q L P   ++    A PP  T P   AP +  T             
Sbjct: 341 LPLAPPSPSAPPSLQTL-PSPPATPPSQA-PPSMTTPPMQAPPSLQTIPPIQVPHSLTSP 398

Query: 549 LLKVPLAPPVWTAPTFTHRQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPA 608
            L+ P +P   ++   T    LGS  L+               M+  Q        S PA
Sbjct: 399 SLQAPPSPLALSSLQAT--TSLGSPTLQATHS--------FLTMSPRQTQASLTSPSRPA 448

Query: 609 AEPPPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSL 668
           + PP +P   L+  LS                      + P  QT      + LSS  ++
Sbjct: 449 STPPDSPP--LQAPLS--------------------LPASPPLQTSLSPAVSPLSSPLTI 486

Query: 669 SGHVDPSEDTSSPHSPEWPPADALPLPP------------TTPPSQELTPDACAQGVPSE 716
             H   +  + + HSP+  P  +L +PP             TPP+   TP    + +PS 
Sbjct: 487 --HPLQALSSLASHSPQ-APLSSLIMPPLETQSSLAPPSLQTPPASLTTPP--LENLPSL 541

Query: 717 QRQMLRDYMAKL-PPQRDTPGC------------ATTPPHSQASSVRATRSQQHTPVLSS 763
               L+   A L  P  +TP C             TTPP    SS+ AT   Q  P L +
Sbjct: 542 APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI-ATPPPQAPPAL-A 599

Query: 764 SQPLRKKP 771
           S PL+  P
Sbjct: 600 SPPLQGLP 607



 Score = 38.1 bits (87), Expect = 0.031
 Identities = 54/182 (29%), Positives = 65/182 (35%), Gaps = 33/182 (18%)

Query: 607 PAAEPPPAPESGLEDKLSERLGE--------AWAGRGAAWWERQQGRTSEP---GRQTRR 655
           PAA   P+   GL+   S  L          A +G  A    R     S+P   G Q  R
Sbjct: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281

Query: 656 PK-----RRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPAD--ALPLPPTTPPSQEL-TPD 707
           P      R+    +   LS     +   S   +   PP D  A PLP T PPS  L TP 
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL 341

Query: 708 ACAQGVPSEQRQMLRDYMAKLPPQRDT-PGCATTPPHSQASSVRATRSQQHTPVLSSSQP 766
             A   PS             PP   T P    TPP SQA     T   Q  P L +  P
Sbjct: 342 PLAPPSPS------------APPSLQTLPSPPATPP-SQAPPSMTTPPMQAPPSLQTIPP 388

Query: 767 LR 768
           ++
Sbjct: 389 IQ 390



 Score = 34.7 bits (78), Expect = 0.35
 Identities = 91/401 (22%), Positives = 121/401 (30%), Gaps = 65/401 (16%)

Query: 402 PPPRPSCVQPLLLGGQGG-QLQLLHLAEGASVPRLAGPPQSLPSRIDSLPAFPL---LEP 457
           PP  P    PL L      Q  L       S P    P Q+L S     P  PL   + P
Sbjct: 451 PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMP 510

Query: 458 KIQWRLQERLKAPTIGL---AAVVPPLPSAPTPGLVLFQLSAAGDVFYQQLRPQVDSSLR 514
            ++   Q  L  P++     +   PPL + P+      Q ++A         P   +   
Sbjct: 511 PLE--TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568

Query: 515 RDAGPPGDTQPDCHAPTASWTSQDTAG---CSQWLKALLKVPLAPPVWTAPTFTHRQMLG 571
             A P   T P    P++  T    A     S  L+ L   PL+P     P       L 
Sbjct: 569 LQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALP 628

Query: 572 STELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSERLGEAW 631
             +          L  L     +    L   L   P + PP  P                
Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV--------------- 673

Query: 632 AGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSG---HVDPSEDTSSPHSPEWPP 688
                      Q   S P      P       +  SL+     V PS   S P SP   P
Sbjct: 674 -----------QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 722

Query: 689 ---------ADALPLPPTTPPSQELTPDAC-------------AQGVPSEQRQMLRDYMA 726
                    A  L +PP+ P S  ++P A               Q  PS    +    +A
Sbjct: 723 PPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLA 782

Query: 727 KLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSSQPL 767
           K PPQ   P    TPP     S  A+   Q     S+S P+
Sbjct: 783 KPPPQ--APPALATPPLQALPSPPASFPGQAPFSPSASLPM 821



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 3/94 (3%)

Query: 680 SPHSPEWPPA-DALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCA 738
           +P SP  PP+   LP PP TPPSQ   P +           +      ++P    +P   
Sbjct: 344 APPSPSAPPSLQTLPSPPATPPSQ--APPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ 401

Query: 739 TTPPHSQASSVRATRSQQHTPVLSSSQPLRKKPR 772
             P     SS++AT S     + ++   L   PR
Sbjct: 402 APPSPLALSSLQATTSLGSPTLQATHSFLTMSPR 435



 Score = 31.2 bits (69), Expect = 3.8
 Identities = 35/108 (32%), Positives = 43/108 (39%), Gaps = 16/108 (14%)

Query: 674 PSEDTSSPHSPEWPPADALPLPPTTPPSQELTPDACA----QGVPSEQRQMLRDYMAKLP 729
           PS    +P SP   PA     P  TPPSQ   P + A    Q  PS          A  P
Sbjct: 669 PSPPVQAPFSP---PASPPVSPSATPPSQ--APPSLAAPPLQVPPSPPASPPMSPSATPP 723

Query: 730 PQRDTPGCA------TTPPHSQASSVRATRSQQHTPVLSSSQPLRKKP 771
           PQ   P  A       +PP S   S  AT   +  P+L ++ PL+  P
Sbjct: 724 PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLL-AAPPLQVPP 770



 Score = 30.0 bits (66), Expect = 8.5
 Identities = 36/123 (29%), Positives = 49/123 (39%), Gaps = 12/123 (9%)

Query: 656 PKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALP---LPPTTPPSQELTPDACAQG 712
           P +     +S  L G   P     +   P+ PP  ALP    PP+ P S  L+P A    
Sbjct: 591 PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLA---- 646

Query: 713 VPSEQR-QMLRDYMAKL---PPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSSQPLR 768
            PS Q    L  ++ +    PP         +PP S   S  AT   Q  P L ++ PL+
Sbjct: 647 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL-AAPPLQ 705

Query: 769 KKP 771
             P
Sbjct: 706 VPP 708


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 85/390 (21%), Positives = 137/390 (35%), Gaps = 55/390 (14%)

Query: 392 PSPLLLARLLPPPRPSCVQPLLLG------GQGGQLQLLHL-AEGA--SVPRLAGPPQSL 442
           PS    A +LPPP        LLG       Q   +++  L AEGA    P    PP   
Sbjct: 359 PSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVE 418

Query: 443 PSRIDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFY 502
            +  D  P  P   P+ + R    L+  T    A+  P   APT     FQ     +   
Sbjct: 419 ETLADVQPLLPEEAPREEAR---ELQLST----AMETPAEEAPTE----FQSPLPKETTA 467

Query: 503 QQLRPQVDSSLRRDAGPPGDTQP-DCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTA 561
           ++   ++   L     PP D  P +  +P +  TS + A       A ++ PLA      
Sbjct: 468 EEASAEIQ--LLAATEPPADETPAEARSPLSEETSAEEA------HAEVQSPLAEETTAE 519

Query: 562 PTFTHRQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLED 621
                 Q+L + E   +E   +    L +  +  +   +      P+A+     E+ LE 
Sbjct: 520 EASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQS---PSAKGVSIEEAPLE- 575

Query: 622 KLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSP 681
            L    GE                T+E      +    T+ S+       V P     +P
Sbjct: 576 -LQPPSGEE--------------TTAEEASAAIQLLAATEASAE-EAPAEVQPPPAEEAP 619

Query: 682 HSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTP 741
              + PPA+  P     PP++E   +   Q  P+E+         + PP  + P     P
Sbjct: 620 AEVQPPPAEEAPAEVQPPPAEEAPAE--VQPPPAEEAPA----EVQPPPAEEAPAEVQPP 673

Query: 742 PHSQASSVRATRSQQHTPVLSSSQPLRKKP 771
           P  +A +   +   + TP+  +   +   P
Sbjct: 674 PAEEAPAEVQSLPAEETPIEETLAAVHSPP 703


>gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo
           sapiens]
          Length = 1198

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 49/197 (24%), Positives = 81/197 (41%), Gaps = 31/197 (15%)

Query: 568 QMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAP--ESGLEDKLSE 625
           + L + E   +E++ +    L + +A+ Q L         AA PP +   E+  ++K   
Sbjct: 641 ECLFTLEAHSQEQKKRVCWCLSENIAKQQQL---------AASPPDSKMFETEADEKREM 691

Query: 626 RLGEAWAGRGAAWWERQQGRTSEPGRQTR----------RPKRRTQLSSSFSLSGHVDPS 675
            L E   G+G    +    +   PG++             P  +    S   LS   D +
Sbjct: 692 ALEE---GKGPGAEDSPPSKEPSPGQELPPGQDLPPNKDSPSGQEPAPSQEPLSSK-DSA 747

Query: 676 EDTSSPHSPEWPPADALPLPPTTPPSQELTP----DACAQGVPSEQRQMLRDYMA-KLPP 730
               SP  P+ PP+  +P     PP+Q+L+P     A  + +P +   + +D  A +  P
Sbjct: 748 TSEGSPPGPDAPPSKDVPPCQEPPPAQDLSPCQDLPAGQEPLPHQDPLLTKDLPAIQESP 807

Query: 731 QRDTPGCATTPPHSQAS 747
            RD P C   PP SQ S
Sbjct: 808 TRDLPPCQDLPP-SQVS 823


>gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo
           sapiens]
          Length = 917

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 49/197 (24%), Positives = 81/197 (41%), Gaps = 31/197 (15%)

Query: 568 QMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAP--ESGLEDKLSE 625
           + L + E   +E++ +    L + +A+ Q L         AA PP +   E+  ++K   
Sbjct: 360 ECLFTLEAHSQEQKKRVCWCLSENIAKQQQL---------AASPPDSKMFETEADEKREM 410

Query: 626 RLGEAWAGRGAAWWERQQGRTSEPGRQTR----------RPKRRTQLSSSFSLSGHVDPS 675
            L E   G+G    +    +   PG++             P  +    S   LS   D +
Sbjct: 411 ALEE---GKGPGAEDSPPSKEPSPGQELPPGQDLPPNKDSPSGQEPAPSQEPLSSK-DSA 466

Query: 676 EDTSSPHSPEWPPADALPLPPTTPPSQELTP----DACAQGVPSEQRQMLRDYMA-KLPP 730
               SP  P+ PP+  +P     PP+Q+L+P     A  + +P +   + +D  A +  P
Sbjct: 467 TSEGSPPGPDAPPSKDVPPCQEPPPAQDLSPCQDLPAGQEPLPHQDPLLTKDLPAIQESP 526

Query: 731 QRDTPGCATTPPHSQAS 747
            RD P C   PP SQ S
Sbjct: 527 TRDLPPCQDLPP-SQVS 542


>gi|239755589 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 356

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 52/188 (27%), Positives = 71/188 (37%), Gaps = 32/188 (17%)

Query: 534 WTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTHR--QMLGSTELRREEEEGQRLGVLRKA 591
           W +Q   G  +   AL      P V+T  +  H   +   S      E EG R G     
Sbjct: 123 WGTQAPCGRLRAKPALQTQRKEPLVFTQRSLLHSSPRWFSSRHSSISEGEGDRCG----- 177

Query: 592 MARGQLLLQRDLGSLPAAEP-PPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPG 650
                   +   GS P A P PP P+ G     ++R  EA     ++W       T+ PG
Sbjct: 178 ------FAEPPGGSSPPAPPLPPPPKPGSP---TQRAREA-----SSWKPPGHSHTAPPG 223

Query: 651 RQTRRP-KRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELTPDAC 709
           R T+RP  +R    SS  LS    P    +S  S    P   LP PP   P+        
Sbjct: 224 RGTQRPLTQRHSSESSSELSSSAWPGTIWTSTLS----PGQRLPTPPPPDPAA-----LT 274

Query: 710 AQGVPSEQ 717
           + G+P +Q
Sbjct: 275 SWGLPQQQ 282


>gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo
           sapiens]
          Length = 519

 Score = 39.3 bits (90), Expect = 0.014
 Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 6/80 (7%)

Query: 673 DPSEDTSSPHSPEWPPADALPLPPTTPPSQELTP----DACAQGVPSEQRQMLRDYMA-K 727
           D +    SP  P+ PP+  +P     PP+Q+L+P     A  + +P +   + +D  A +
Sbjct: 66  DSATSEGSPPGPDAPPSKDVPPCQEPPPAQDLSPCQDLPAGQEPLPHQDPLLTKDLPAIQ 125

Query: 728 LPPQRDTPGCATTPPHSQAS 747
             P RD P C   PP SQ S
Sbjct: 126 ESPTRDLPPCQDLPP-SQVS 144


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 38.9 bits (89), Expect = 0.018
 Identities = 31/91 (34%), Positives = 33/91 (36%), Gaps = 6/91 (6%)

Query: 674  PSEDTSSPHSP-----EWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKL 728
            P++   SPH         PP  ALP  PT PP   L P       P    Q  R     L
Sbjct: 921  PTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVL 980

Query: 729  PPQRDTPGCATTPPHSQASSVRATRSQQHTP 759
            PPQ   P     PP   A  VR    Q H P
Sbjct: 981  PPQPMLPPQPVLPP-QPALPVRPEPLQPHLP 1010



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 26/96 (27%), Positives = 38/96 (39%), Gaps = 15/96 (15%)

Query: 392 PSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLAEGASVPRLAGPPQSLPSRIDSLPA 451
           P P++  + +PP  P  + P    G   QL+ L + +    P    PPQ  P     +P 
Sbjct: 746 PQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPP-----IPV 800

Query: 452 FPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTP 487
            P + P           A   GL   +P LP+A  P
Sbjct: 801 VPPITP----------LAGIDGLPPALPDLPTATVP 826


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 38.5 bits (88), Expect = 0.024
 Identities = 36/136 (26%), Positives = 47/136 (34%), Gaps = 10/136 (7%)

Query: 646  TSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHS--PEWPPADALPLPPTTPPSQE 703
            T+ P   T  P   T   S  + +    P   T SP +  P  PPA    LPPTT PS  
Sbjct: 1467 TTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPP 1526

Query: 704  LT-----PDACAQGVPSEQRQMLRDYMAKLPP---QRDTPGCATTPPHSQASSVRATRSQ 755
             T     P       P+            LPP       P   TTPP +   S   T + 
Sbjct: 1527 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTP 1586

Query: 756  QHTPVLSSSQPLRKKP 771
                + +++ P    P
Sbjct: 1587 SPPTITTTTPPPTTTP 1602



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 32/119 (26%), Positives = 39/119 (32%), Gaps = 6/119 (5%)

Query: 647  SEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHS-PEWPPADALPLPPTTPPSQELT 705
            S P   T  P   T  S   + +    P+   S P + P  PP     LPPTT PS   T
Sbjct: 1587 SPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPT 1646

Query: 706  -----PDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTP 759
                 P       P+             PP   TP    T   S  ++   T S   TP
Sbjct: 1647 TTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTP 1705



 Score = 30.4 bits (67), Expect = 6.5
 Identities = 28/97 (28%), Positives = 34/97 (35%), Gaps = 26/97 (26%)

Query: 674  PSEDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRD 733
            PS  T++P SP  PP     LPPTT PS   T                       PP   
Sbjct: 1399 PSPPTTTP-SP--PPTSTTTLPPTTTPSPPTT-------------------TTTTPPPTT 1436

Query: 734  TPG----CATTPPHSQASSVRATRSQQHTPVLSSSQP 766
            TP       TTPP +   S   + +    P  + S P
Sbjct: 1437 TPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPP 1473



 Score = 30.4 bits (67), Expect = 6.5
 Identities = 29/103 (28%), Positives = 35/103 (33%), Gaps = 13/103 (12%)

Query: 647  SEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEW-PPADALPLPPTTPPSQELT 705
            S P   T  P   T  S   + +    P+   S P S    PP    P PPTT PS    
Sbjct: 1423 SPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPS---- 1478

Query: 706  PDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASS 748
            P       P+             PP   TP   TT P +  +S
Sbjct: 1479 PPTTTPSPPTT--------TTTTPPPTTTPSPPTTTPITPPAS 1513


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 38.5 bits (88), Expect = 0.024
 Identities = 30/89 (33%), Positives = 39/89 (43%), Gaps = 10/89 (11%)

Query: 658  RRTQLSSSFSLSGHVDPS----EDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGV 713
            R  Q S S ++S   DP     +DTS+P  P   PA A+P PP  P      P A + G 
Sbjct: 1392 RDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPG----LPSANSNGT 1447

Query: 714  PSEQRQMLRDYMAKLPPQRDTPGCATTPP 742
            P  +  +L +     PP   TP     PP
Sbjct: 1448 P--EPPLLEEKPPPTPPPAPTPQPQPPPP 1474



 Score = 30.4 bits (67), Expect = 6.5
 Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 6/96 (6%)

Query: 676  EDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTP 735
            E T+S   PE  P  A+P PP       L P         ++++ +      L  +R T 
Sbjct: 1707 EKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVE-----KEKEKEKVTRGERPLRGERATS 1761

Query: 736  GCATTPPHSQASSVRAT-RSQQHTPVLSSSQPLRKK 770
            G  T P  S A+   AT R  +  P    ++P  KK
Sbjct: 1762 GRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKK 1797


>gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]
          Length = 1243

 Score = 38.1 bits (87), Expect = 0.031
 Identities = 35/117 (29%), Positives = 47/117 (40%), Gaps = 16/117 (13%)

Query: 662  LSSSFSLS------GHVDPSEDTSSPHSPEWP-PADALPLPPTTPPSQELTPDACAQGVP 714
            L+S+FSL+        + PS    S   P  P P  +LPLPP   P  + +P      V 
Sbjct: 926  LASAFSLAVMTVAQSLLSPSPGLLSQSPPAPPSPLPSLPLPPPVAPGGQESPSPHTAEVE 985

Query: 715  SEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSSQPLRKKP 771
            SE         A  PP R  PG A   P S+    +     Q T     ++PL  +P
Sbjct: 986  SE---------ASPPPARPLPGEARLAPISEEGKPQLVGRFQVTSSKEPAEPLPLQP 1033



 Score = 31.6 bits (70), Expect = 2.9
 Identities = 37/144 (25%), Positives = 51/144 (35%), Gaps = 19/144 (13%)

Query: 345 VLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLKWNHGLPSPLLLARLLPPP 404
           V L+Q    S P   PPT    C+Q +L       P  P        PS           
Sbjct: 874 VPLSQCPWSSLPTTSPPTFSPTCSQVTL-----SSPFFPPCPSTSSFPS----------- 917

Query: 405 RPSCVQPLLLGGQGGQLQLLHLAEGASVPRLAGPPQSLPSRIDSLPAFPLLEPKIQWRLQ 464
             +   PLL       L ++ +A+    P      QS P+    LP+ P L P +    Q
Sbjct: 918 --TTAAPLLSLASAFSLAVMTVAQSLLSPSPGLLSQSPPAPPSPLPSLP-LPPPVAPGGQ 974

Query: 465 ERLKAPTIGLAAVVPPLPSAPTPG 488
           E     T  + +   P P+ P PG
Sbjct: 975 ESPSPHTAEVESEASPPPARPLPG 998


>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
          Length = 2603

 Score = 38.1 bits (87), Expect = 0.031
 Identities = 42/169 (24%), Positives = 59/169 (34%), Gaps = 36/169 (21%)

Query: 605  SLPAAEPPPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSS 664
            S P++  PPA   G+        G A   + A+  E++ G  S P  +T   +     SS
Sbjct: 2041 SSPSSPSPPAQPGGVSRNSPLDCGSASPNKVASSSEQEAG--SPPVVETTNTRPPNSSSS 2098

Query: 665  SFSLSGHVDPSEDTSSPHSPEWPPADALPLPP-----TTPP------------------S 701
            S S S H +  +   S      PP     +PP     T PP                   
Sbjct: 2099 SGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYP 2158

Query: 702  QELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVR 750
               TP  C Q  P  +   +R      PP        TT PH  ++SV+
Sbjct: 2159 MPQTPMGCPQPTPKMETPAIRP-----PPH------GTTAPHKNSASVQ 2196


>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sapiens]
          Length = 2352

 Score = 38.1 bits (87), Expect = 0.031
 Identities = 42/169 (24%), Positives = 59/169 (34%), Gaps = 36/169 (21%)

Query: 605  SLPAAEPPPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSS 664
            S P++  PPA   G+        G A   + A+  E++ G  S P  +T   +     SS
Sbjct: 1790 SSPSSPSPPAQPGGVSRNSPLDCGSASPNKVASSSEQEAG--SPPVVETTNTRPPNSSSS 1847

Query: 665  SFSLSGHVDPSEDTSSPHSPEWPPADALPLPP-----TTPP------------------S 701
            S S S H +  +   S      PP     +PP     T PP                   
Sbjct: 1848 SGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYP 1907

Query: 702  QELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVR 750
               TP  C Q  P  +   +R      PP        TT PH  ++SV+
Sbjct: 1908 MPQTPMGCPQPTPKMETPAIRP-----PPH------GTTAPHKNSASVQ 1945


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 37.7 bits (86), Expect = 0.041
 Identities = 51/192 (26%), Positives = 74/192 (38%), Gaps = 13/192 (6%)

Query: 391  LPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLAEGASVPRLAGP---PQSLPSRID 447
            LP+P L     P P P+ V+PLL        ++   A GA+   ++ P   P SLP    
Sbjct: 1353 LPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPAS 1412

Query: 448  S-LP---AFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAP--TPGLVLFQLSAAGDVF 501
            S +P   + PL  P           +  I +   +P   SAP   P      +SA+G   
Sbjct: 1413 SPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPAL 1472

Query: 502  YQQLRPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTA 561
               + P +   +    GPP    P   +P+AS     T G +             P+  A
Sbjct: 1473 LTSVTPPLAPVVPAAPGPP-SLAPSGASPSASAL---TLGLATAPSLSSSQTPGHPLLLA 1528

Query: 562  PTFTHRQMLGST 573
            PT +H   L ST
Sbjct: 1529 PTSSHVPGLNST 1540


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 37.4 bits (85), Expect = 0.053
 Identities = 36/116 (31%), Positives = 49/116 (42%), Gaps = 12/116 (10%)

Query: 656 PKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPP-ADALPLPPTTPPSQELTPDACAQGVP 714
           P  R + +   +++G + P +  SSP  P  PP  D  P   TT  ++E    A A  +P
Sbjct: 2   PGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELP 61

Query: 715 SEQRQMLRDYMAKLPPQR-----DTP---GCATTPPHS---QASSVRATRSQQHTP 759
             Q +  RD   K P  R      TP   G   TPP     QA S  A R++   P
Sbjct: 62  EAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPP 117



 Score = 34.3 bits (77), Expect = 0.45
 Identities = 32/109 (29%), Positives = 46/109 (42%), Gaps = 10/109 (9%)

Query: 614  APESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVD 673
            A E+G +    +R+       GAA  E+  G+     R    P R T+       SG  +
Sbjct: 2688 AGETGAQKPPGDRMLCPGRMDGAALGEQPTGQKGASARGFWGP-RETKALGVCKESGS-E 2745

Query: 674  PSEDTSSPHSPE----W----PPADALPLPPTTPPSQELTPDACAQGVP 714
            P+ED+S  HS      W    PP   L  P T+    + T  +C QG+P
Sbjct: 2746 PAEDSSRAHSRSEEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLP 2794



 Score = 31.6 bits (70), Expect = 2.9
 Identities = 39/159 (24%), Positives = 61/159 (38%), Gaps = 25/159 (15%)

Query: 594  RGQLLLQRDLGSLPAAEPPPAPESGLEDKLSE----------RLGEAWAGRGAAWWERQQ 643
            RGQ   +R LG LP      +  + L + ++E            G+A    G  W +  +
Sbjct: 3176 RGQA--RRSLGDLPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGE 3233

Query: 644  GRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQE 703
             +   PG +  +P+ R+  S+     G   P   +++  +    P      PP T PS  
Sbjct: 3234 AKKDSPGERA-KPRARSTPSNP---DGAATPDSASATALADAGSPG-----PPRTTPSP- 3283

Query: 704  LTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPP 742
             +PD  A G P  Q   + +  A   P RD   C    P
Sbjct: 3284 -SPDPWAGGEPLLQATPVHE--ACKDPSRDCHHCGKRFP 3319


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 37.4 bits (85), Expect = 0.053
 Identities = 47/180 (26%), Positives = 69/180 (38%), Gaps = 26/180 (14%)

Query: 576 RREEEEGQRLGVLRKAMARGQLL------------LQRDLGSLPAAEPPPAPESGLEDKL 623
           RR EEE +R+   R+A    +L             L+ +  + PAA   PAP   +  +L
Sbjct: 469 RRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKEL 528

Query: 624 SERLGEAWAGRGAAWWERQQGRTSEPGRQTRRP---KRRTQLSSSFSLSGHVDPSEDTSS 680
                   A       E ++   + P + T  P      T +S   S S     S + +S
Sbjct: 529 PAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFE-AS 587

Query: 681 PHSPEWP------PADALPLPPTTPPSQELTPDACAQG---VPSEQRQMLRDYMAKLPPQ 731
           P  P+ P      P + +P PPTTPP  ++ P     G    P  Q      Y   LPP+
Sbjct: 588 PVEPQLPSKEGPEPPEEVP-PPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPR 646



 Score = 30.8 bits (68), Expect = 5.0
 Identities = 44/187 (23%), Positives = 63/187 (33%), Gaps = 39/187 (20%)

Query: 607 PAAEPPPAPESGLE--DKLSERLGEAWAG--RGAAWWERQQGRTSEPGRQTRRPKRRTQL 662
           P   P    E  L+  D+L +   + WAG      + E+ +    E GR +         
Sbjct: 300 PVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHR 359

Query: 663 SSSFSLSGHVDPSEDT----SSPHS---------------PEWPPADALPLPPTTPPSQE 703
            S  S SG   P E      +SP+S               PE  P    P PP  PP + 
Sbjct: 360 DSQ-SASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHR- 417

Query: 704 LTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSS 763
               A   G P        DY     P R  P C    P  +  + R  R Q  + +  +
Sbjct: 418 --GPAGNWGPPG-------DY-----PDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLA 463

Query: 764 SQPLRKK 770
            +  R++
Sbjct: 464 VERARRR 470


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 37.4 bits (85), Expect = 0.053
 Identities = 41/136 (30%), Positives = 58/136 (42%), Gaps = 19/136 (13%)

Query: 646 TSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELT 705
           T   G+   +P   +QLS+    S  + P +  +  H P  PP  A PL  T P SQ   
Sbjct: 679 TQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPN--HPPPQPPTQATPLMHTKPNSQG-P 735

Query: 706 PDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATR---------SQQ 756
           P+  A  +PSE      +  +  PPQ  TP  +T P   Q  S+ A +         +Q 
Sbjct: 736 PNPMA--LPSEHG---LEQPSHTPPQTPTPP-STPPLGKQNPSLPAPQTLAGGNPETAQP 789

Query: 757 HTPVLSSSQPLRKKPR 772
           H   L   +P+  KPR
Sbjct: 790 HAGTLPRPRPV-PKPR 804


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 37.4 bits (85), Expect = 0.053
 Identities = 41/136 (30%), Positives = 58/136 (42%), Gaps = 19/136 (13%)

Query: 646 TSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELT 705
           T   G+   +P   +QLS+    S  + P +  +  H P  PP  A PL  T P SQ   
Sbjct: 601 TQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPN--HPPPQPPTQATPLMHTKPNSQG-P 657

Query: 706 PDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATR---------SQQ 756
           P+  A  +PSE      +  +  PPQ  TP  +T P   Q  S+ A +         +Q 
Sbjct: 658 PNPMA--LPSEHG---LEQPSHTPPQTPTPP-STPPLGKQNPSLPAPQTLAGGNPETAQP 711

Query: 757 HTPVLSSSQPLRKKPR 772
           H   L   +P+  KPR
Sbjct: 712 HAGTLPRPRPV-PKPR 726


>gi|89941470 ankyrin repeat domain 34 [Homo sapiens]
          Length = 496

 Score = 37.4 bits (85), Expect = 0.053
 Identities = 94/356 (26%), Positives = 122/356 (34%), Gaps = 74/356 (20%)

Query: 392 PSPLLLARLLPPPRPS-CVQP----LLLGGQGGQLQLLHLAEGASVPR------LAGPPQ 440
           PSP +       P P  C  P    L   G GG+  L   A+     R      L  PP 
Sbjct: 164 PSPGVEDPAPASPSPGFCTSPSEIQLQTAGGGGRGMLSPRAQEEEEKRDVFEFPLPKPPD 223

Query: 441 SLPSRIDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLV-LFQLSAAGD 499
             PS  + LP  P   PK      +RL +   GL A  PP P  PT G   + +L+A  +
Sbjct: 224 D-PSPSEPLPKPPRHPPKPL----KRLNSEPWGLVA--PPQPVPPTEGRPGIERLTAEFN 276

Query: 500 VFYQQLRPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVW 559
                 RP++  S R     P D  P        W  + T+G       L +   AP   
Sbjct: 277 GLTLTGRPRL--SRRHSTEGPEDPPP--------WAEKVTSG-----GPLSRRNTAPEAQ 321

Query: 560 -TAPTFTHRQMLGSTE---------LRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAA 609
            + P    RQ L   E         L  +  E  RL + R+  +   L       +LP A
Sbjct: 322 ESGPPSGLRQKLSRMEPVELDTPGHLCPDSPESSRLSLERRRYSASPL-------TLPPA 374

Query: 610 EPPPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLS 669
              P+P    E              GA       GR   PG   RR        S   L 
Sbjct: 375 GSAPSPRQSQESL-----------PGAV--SPLSGRRRSPGLLERR-------GSGTLLL 414

Query: 670 GHVDPSEDTSSPH---SPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLR 722
            H+  +     P    SP  P  D  P P    PS    P A A G P  +R+++R
Sbjct: 415 DHISQTRPGFLPPLNVSPHPPIPDIRPQPGGRAPSLPAPPYAGAPGSPRTKRKLVR 470


>gi|239582735 radial spoke head 4 homolog A isoform 2 [Homo sapiens]
          Length = 600

 Score = 37.0 bits (84), Expect = 0.070
 Identities = 43/162 (26%), Positives = 62/162 (38%), Gaps = 31/162 (19%)

Query: 620 EDKLSERLGEA---WAGRGAAWWERQQGRTSEP---------GRQTRRPKR-RTQLSSSF 666
           E +  E LGE    W G+ AA  +  +  +SEP         GRQ+R  +    Q  +  
Sbjct: 10  EKENQEELGETRRPWEGKTAASPQYSEPESSEPLEAKQGPETGRQSRSSRPWSPQSRAKT 69

Query: 667 SLSGHVDPSEDTSSPHSPEWPPADALPLPP-----TTPPSQELTPDACAQ-GVPSEQRQM 720
            L G   P   + +P SP  P +   PL P       PP  + T     + G P      
Sbjct: 70  PLGGPAGPETSSPAPVSPREPSSSPSPLAPARQDLAAPPQSDRTTSVIPEAGTPYPD--- 126

Query: 721 LRDYMAKLPPQRDTPGCATTPPH-SQASSVRATRSQQHTPVL 761
                   P ++ +    +TP H SQ+      +SQQ  P L
Sbjct: 127 --------PLEQSSDKRESTPHHTSQSEGNTFQQSQQPKPHL 160


>gi|58219006 radial spoke head 4 homolog A isoform 1 [Homo sapiens]
          Length = 716

 Score = 37.0 bits (84), Expect = 0.070
 Identities = 43/162 (26%), Positives = 62/162 (38%), Gaps = 31/162 (19%)

Query: 620 EDKLSERLGEA---WAGRGAAWWERQQGRTSEP---------GRQTRRPKR-RTQLSSSF 666
           E +  E LGE    W G+ AA  +  +  +SEP         GRQ+R  +    Q  +  
Sbjct: 10  EKENQEELGETRRPWEGKTAASPQYSEPESSEPLEAKQGPETGRQSRSSRPWSPQSRAKT 69

Query: 667 SLSGHVDPSEDTSSPHSPEWPPADALPLPP-----TTPPSQELTPDACAQ-GVPSEQRQM 720
            L G   P   + +P SP  P +   PL P       PP  + T     + G P      
Sbjct: 70  PLGGPAGPETSSPAPVSPREPSSSPSPLAPARQDLAAPPQSDRTTSVIPEAGTPYPD--- 126

Query: 721 LRDYMAKLPPQRDTPGCATTPPH-SQASSVRATRSQQHTPVL 761
                   P ++ +    +TP H SQ+      +SQQ  P L
Sbjct: 127 --------PLEQSSDKRESTPHHTSQSEGNTFQQSQQPKPHL 160


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 37.0 bits (84), Expect = 0.070
 Identities = 51/190 (26%), Positives = 64/190 (33%), Gaps = 26/190 (13%)

Query: 602 DLGSLPAAEPPPAPESGLEDKLS-ERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPK--- 657
           D+GS P + PPP P +    + S    G      G    +   G T  P    R      
Sbjct: 175 DVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPR--QPSPGPTPPPFPGNRGTALGG 232

Query: 658 ---RRTQLSSSFSLSGHVD----PSEDTSSPHSPEWPPADALP------LPPTTPPSQEL 704
              R++ LSSS   S        PS        P  PP    P      +PP  PP Q  
Sbjct: 233 GSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPP--PPPQNN 290

Query: 705 TPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSS 764
            P      VPS  R          PP    PG    PP S  +       Q++  + SS+
Sbjct: 291 KPP-----VPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSST 345

Query: 765 QPLRKKPRMG 774
            PL    R G
Sbjct: 346 PPLPSPGRSG 355



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 29/102 (28%), Positives = 36/102 (35%), Gaps = 11/102 (10%)

Query: 654 RRPKRRTQLSSSF------SLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELTPD 707
           R P+R   LSSS         SG + P      P     PP  + PLPP  P S+  +  
Sbjct: 333 RLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTS 392

Query: 708 ACAQGVPSEQRQMLRDY-----MAKLPPQRDTPGCATTPPHS 744
                 P    +   D         LPP R + G    PP S
Sbjct: 393 RALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPS 434


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 37.0 bits (84), Expect = 0.070
 Identities = 51/190 (26%), Positives = 64/190 (33%), Gaps = 26/190 (13%)

Query: 602 DLGSLPAAEPPPAPESGLEDKLS-ERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPK--- 657
           D+GS P + PPP P +    + S    G      G    +   G T  P    R      
Sbjct: 175 DVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPR--QPSPGPTPPPFPGNRGTALGG 232

Query: 658 ---RRTQLSSSFSLSGHVD----PSEDTSSPHSPEWPPADALP------LPPTTPPSQEL 704
              R++ LSSS   S        PS        P  PP    P      +PP  PP Q  
Sbjct: 233 GSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPP--PPPQNN 290

Query: 705 TPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSS 764
            P      VPS  R          PP    PG    PP S  +       Q++  + SS+
Sbjct: 291 KPP-----VPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSST 345

Query: 765 QPLRKKPRMG 774
            PL    R G
Sbjct: 346 PPLPSPGRSG 355



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 29/102 (28%), Positives = 36/102 (35%), Gaps = 11/102 (10%)

Query: 654 RRPKRRTQLSSSF------SLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELTPD 707
           R P+R   LSSS         SG + P      P     PP  + PLPP  P S+  +  
Sbjct: 333 RLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTS 392

Query: 708 ACAQGVPSEQRQMLRDY-----MAKLPPQRDTPGCATTPPHS 744
                 P    +   D         LPP R + G    PP S
Sbjct: 393 RALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPS 434


>gi|24308394 hypothetical protein LOC140893 [Homo sapiens]
          Length = 664

 Score = 37.0 bits (84), Expect = 0.070
 Identities = 81/348 (23%), Positives = 121/348 (34%), Gaps = 61/348 (17%)

Query: 426 LAEGASVPRLAGPPQSLPSRIDSL--PAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPS 483
           ++ GA++P    P  S P RI +       ++ P  Q    +R   P  G     PPLP+
Sbjct: 195 ISPGATLPESRAPDMS-PQRISNQLHGTIAVVRPGSQACPADR--GPANGTP---PPLPA 248

Query: 484 APTPGLVLFQLSAAGDVFYQQLRPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCS 543
             +P    ++   + D F +  RP   +       P  D     + P            S
Sbjct: 249 RSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPL-----------S 297

Query: 544 QWLKALLKVPLAPPVWTAPTFTHRQMLGSTELRREEEEGQRLGV---------------L 588
             L++    PLAP    AP+    Q L + E    EE  + LG+               L
Sbjct: 298 LHLQSPHSSPLAPAA--APSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGAL 355

Query: 589 RKAMARGQLLLQRDLGSL-PAAEPPPAPE-------SGLEDKLSERLGEAWAGRGAAWWE 640
              +A+ QL  +   GS+ P  +P P          S  E   +E    A A  G +   
Sbjct: 356 HLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSG-- 413

Query: 641 RQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSE-------DTSSP---HSPEWPPA- 689
              GR ++P    R  +     +   +L   +D SE       DT  P   H    P A 
Sbjct: 414 ---GRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAA 470

Query: 690 -DALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPG 736
             A P PPT       +P A + G    +     +    + P R  PG
Sbjct: 471 HTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPG 518


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 36.6 bits (83), Expect = 0.091
 Identities = 33/114 (28%), Positives = 49/114 (42%), Gaps = 4/114 (3%)

Query: 646  TSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELT 705
            TS     T +P  RT  S + ++S   +P  +++ P +PE PP+ +   P T  P+   T
Sbjct: 1336 TSTDQPVTPKPTSRTTRSRT-NMSSVKNP--ESTVPIAPELPPSTSTEQPVTPEPTSRAT 1392

Query: 706  PDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTP 759
                 +    +  + L     KL P   T    T  P SQA+  R  RS   TP
Sbjct: 1393 RGRKNRS-SGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTP 1445



 Score = 33.5 bits (75), Expect = 0.77
 Identities = 32/103 (31%), Positives = 44/103 (42%), Gaps = 11/103 (10%)

Query: 434  RLAGPPQSLPSRIDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAP----TP-- 487
            R AG P SL + ID  P    LEPK Q    +R  A     +    P P++P    TP  
Sbjct: 1725 RAAGNPGSLAAPIDHKPCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIH 1784

Query: 488  GLVLFQLSAAG-DVFYQQLRPQVDSSLRRDA----GPPGDTQP 525
               + ++  AG   F  +L+P+   S +R       PP   QP
Sbjct: 1785 ASQIQKVEPAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQP 1827



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 27/104 (25%), Positives = 45/104 (43%), Gaps = 2/104 (1%)

Query: 656  PKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPS 715
            PK  +Q + S +    V   E    P +PE  P+ +   P T+ P+ ++T    ++    
Sbjct: 1139 PKPTSQATRSRTNRSSVKTPEPVV-PTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVK 1197

Query: 716  EQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTP 759
                ++   + +L P   T    T+ P SQA+  R  RS   TP
Sbjct: 1198 TPETVVPTAL-ELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTP 1240



 Score = 32.3 bits (72), Expect = 1.7
 Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 8/99 (8%)

Query: 679  SSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSE--QRQMLRDYMAKLPPQRDTPG 736
            SS  +P+     A  L P TP  Q +TP+A AQG  S+  +   +R       P+  +P 
Sbjct: 1645 SSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPV 1704

Query: 737  CATTP----PHSQASSVRATRSQQHTPVLSSSQPLRKKP 771
                P    P +Q S ++  R+  +   L++  P+  KP
Sbjct: 1705 TTDQPISPEPITQPSCIKRQRAAGNPGSLAA--PIDHKP 1741



 Score = 31.2 bits (69), Expect = 3.8
 Identities = 25/91 (27%), Positives = 36/91 (39%), Gaps = 7/91 (7%)

Query: 676  EDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQR-------QMLRDYMAKL 728
            ++ SS  +PE     A  L P+T   Q +TP+  +Q              + +     +L
Sbjct: 1396 KNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPEL 1455

Query: 729  PPQRDTPGCATTPPHSQASSVRATRSQQHTP 759
             P   T    T  P SQA+  R  RS   TP
Sbjct: 1456 QPSTSTDQPVTPEPTSQATRGRTDRSSVKTP 1486



 Score = 30.4 bits (67), Expect = 6.5
 Identities = 32/129 (24%), Positives = 50/129 (38%), Gaps = 7/129 (5%)

Query: 646  TSEP-GRQTRRPKRRTQLSSSFSL---SGHVDPSEDTSSPHSPEWPPADALPLPPTTPPS 701
            TSEP  R TR  K R+ + +  ++   +  + PS  T  P +PE P + A      T  S
Sbjct: 1507 TSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPE-PTSRATR--GRTNRS 1563

Query: 702  QELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVL 761
               TP++     P  Q    R+ +    P      C T     +        + +  P  
Sbjct: 1564 SVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTT 1623

Query: 762  SSSQPLRKK 770
            S+ QP+  K
Sbjct: 1624 STDQPVTPK 1632


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,592,541
Number of Sequences: 37866
Number of extensions: 2189396
Number of successful extensions: 10671
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 272
Number of HSP's that attempted gapping in prelim test: 9841
Number of HSP's gapped (non-prelim): 996
length of query: 775
length of database: 18,247,518
effective HSP length: 110
effective length of query: 665
effective length of database: 14,082,258
effective search space: 9364701570
effective search space used: 9364701570
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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