Search of human proteins with 215272390

Search of human proteins with 215272390

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|215272390 solute carrier family 18 (vesicular monoamine),
member 1 isoform b [Homo sapiens]
         (493 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|215272390 solute carrier family 18 (vesicular monoamine), mem...   973   0.0  
gi|208879454 solute carrier family 18 (vesicular monoamine), mem...   956   0.0  
gi|4506987 solute carrier family 18 (vesicular monoamine), membe...   956   0.0  
gi|215272392 solute carrier family 18 (vesicular monoamine), mem...   791   0.0  
gi|42476325 solute carrier family 18 (vesicular monoamine), memb...   582   e-166
gi|118582257 vesicular acetylcholine transporter [Homo sapiens]       292   4e-79
gi|16445357 hypothetical protein LOC116843 [Homo sapiens]              85   1e-16
gi|24431958 solute carrier family 16, member 7 [Homo sapiens]          41   0.003
gi|115583685 solute carrier family 16, member 1 [Homo sapiens]         40   0.005
gi|109288010 solute carrier family 16, member 3 [Homo sapiens]         39   0.008
gi|109288012 solute carrier family 16, member 3 [Homo sapiens]         39   0.008
gi|4759112 solute carrier family 16, member 3 [Homo sapiens]           39   0.008
gi|6912666 sialin [Homo sapiens]                                       39   0.011
gi|4759116 solute carrier family 16, member 5 [Homo sapiens]           38   0.024
gi|225703102 major facilitator superfamily domain containing 10 ...    37   0.031
gi|169217968 PREDICTED: similar to solute carrier family 16, mem...    37   0.031
gi|225703104 major facilitator superfamily domain containing 10 ...    37   0.031
gi|34916028 solute carrier family 16 (monocarboxylic acid transp...    37   0.054
gi|4507021 solute carrier family 4, anion exchanger, member 1 [H...    35   0.12 
gi|21553331 solute carrier family 2 (facilitated glucose transpo...    35   0.16 
gi|156071474 solute carrier family 4, anion exchanger, member 2 ...    35   0.20 
gi|213021148 SVOP-like isoform 1 [Homo sapiens]                        33   0.45 
gi|114796626 solute carrier family 16, member 8 [Homo sapiens]         33   0.59 
gi|42542381 solute carrier family 28, member 1 isoform 1 [Homo s...    32   1.0  
gi|5730045 solute carrier family 16, member 2 [Homo sapiens]           32   1.3  
gi|4503847 solute carrier family 37 (glucose-6-phosphate transpo...    32   1.3  
gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa...    31   2.3  
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap...    31   2.3  
gi|166795299 solute carrier family 2 (facilitated glucose transp...    31   2.3  
gi|41327156 solute carrier family 16 (monocarboxylic acid transp...    31   2.3  

>gi|215272390 solute carrier family 18 (vesicular monoamine), member
           1 isoform b [Homo sapiens]
          Length = 493

 Score =  973 bits (2515), Expect = 0.0
 Identities = 493/493 (100%), Positives = 493/493 (100%)

Query: 1   MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS 60
           MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS
Sbjct: 1   MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS 60

Query: 61  LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA 120
           LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA
Sbjct: 61  LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA 120

Query: 121 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS 180
           HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS
Sbjct: 121 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS 180

Query: 181 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL 240
           TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL
Sbjct: 181 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL 240

Query: 241 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP 300
           LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP
Sbjct: 241 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP 300

Query: 301 YILVAAGLAFLPASVSYLIGTNLFGVLANKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGL 360
           YILVAAGLAFLPASVSYLIGTNLFGVLANKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGL
Sbjct: 301 YILVAAGLAFLPASVSYLIGTNLFGVLANKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGL 360

Query: 361 IGPNAGLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFAIGPSTGGAIV 420
           IGPNAGLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFAIGPSTGGAIV
Sbjct: 361 IGPNAGLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFAIGPSTGGAIV 420

Query: 421 KAIGFPWLMVITGVINIVYAPLCYYLRSPPAKEEKLAILSQDCPMETRMYATQKPTKEFP 480
           KAIGFPWLMVITGVINIVYAPLCYYLRSPPAKEEKLAILSQDCPMETRMYATQKPTKEFP
Sbjct: 421 KAIGFPWLMVITGVINIVYAPLCYYLRSPPAKEEKLAILSQDCPMETRMYATQKPTKEFP 480

Query: 481 LGEDSDEEPDHEE 493
           LGEDSDEEPDHEE
Sbjct: 481 LGEDSDEEPDHEE 493


>gi|208879454 solute carrier family 18 (vesicular monoamine), member
           1 isoform a [Homo sapiens]
          Length = 525

 Score =  956 bits (2472), Expect = 0.0
 Identities = 493/525 (93%), Positives = 493/525 (93%), Gaps = 32/525 (6%)

Query: 1   MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS 60
           MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS
Sbjct: 1   MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS 60

Query: 61  LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA 120
           LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA
Sbjct: 61  LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA 120

Query: 121 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS 180
           HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS
Sbjct: 121 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS 180

Query: 181 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL 240
           TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL
Sbjct: 181 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL 240

Query: 241 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP 300
           LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP
Sbjct: 241 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP 300

Query: 301 YILVAA--------------------------------GLAFLPASVSYLIGTNLFGVLA 328
           YILVAA                                GLAFLPASVSYLIGTNLFGVLA
Sbjct: 301 YILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLA 360

Query: 329 NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL 388
           NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL
Sbjct: 361 NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL 420

Query: 389 RHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRS 448
           RHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRS
Sbjct: 421 RHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRS 480

Query: 449 PPAKEEKLAILSQDCPMETRMYATQKPTKEFPLGEDSDEEPDHEE 493
           PPAKEEKLAILSQDCPMETRMYATQKPTKEFPLGEDSDEEPDHEE
Sbjct: 481 PPAKEEKLAILSQDCPMETRMYATQKPTKEFPLGEDSDEEPDHEE 525


>gi|4506987 solute carrier family 18 (vesicular monoamine), member 1
           isoform a [Homo sapiens]
          Length = 525

 Score =  956 bits (2472), Expect = 0.0
 Identities = 493/525 (93%), Positives = 493/525 (93%), Gaps = 32/525 (6%)

Query: 1   MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS 60
           MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS
Sbjct: 1   MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS 60

Query: 61  LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA 120
           LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA
Sbjct: 61  LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA 120

Query: 121 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS 180
           HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS
Sbjct: 121 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS 180

Query: 181 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL 240
           TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL
Sbjct: 181 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL 240

Query: 241 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP 300
           LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP
Sbjct: 241 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP 300

Query: 301 YILVAA--------------------------------GLAFLPASVSYLIGTNLFGVLA 328
           YILVAA                                GLAFLPASVSYLIGTNLFGVLA
Sbjct: 301 YILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLA 360

Query: 329 NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL 388
           NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL
Sbjct: 361 NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL 420

Query: 389 RHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRS 448
           RHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRS
Sbjct: 421 RHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRS 480

Query: 449 PPAKEEKLAILSQDCPMETRMYATQKPTKEFPLGEDSDEEPDHEE 493
           PPAKEEKLAILSQDCPMETRMYATQKPTKEFPLGEDSDEEPDHEE
Sbjct: 481 PPAKEEKLAILSQDCPMETRMYATQKPTKEFPLGEDSDEEPDHEE 525


>gi|215272392 solute carrier family 18 (vesicular monoamine), member
           1 isoform c [Homo sapiens]
          Length = 472

 Score =  791 bits (2044), Expect = 0.0
 Identities = 414/449 (92%), Positives = 414/449 (92%), Gaps = 32/449 (7%)

Query: 1   MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS 60
           MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS
Sbjct: 1   MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS 60

Query: 61  LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA 120
           LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA
Sbjct: 61  LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA 120

Query: 121 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS 180
           HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS
Sbjct: 121 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS 180

Query: 181 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL 240
           TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL
Sbjct: 181 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL 240

Query: 241 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP 300
           LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP
Sbjct: 241 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP 300

Query: 301 YILVAA--------------------------------GLAFLPASVSYLIGTNLFGVLA 328
           YILVAA                                GLAFLPASVSYLIGTNLFGVLA
Sbjct: 301 YILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLA 360

Query: 329 NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL 388
           NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL
Sbjct: 361 NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL 420

Query: 389 RHTSVYGSVYAIADVAFCMGFAIGPSTGG 417
           RHTSVYGSVYAIADVAFCMGFAIG S  G
Sbjct: 421 RHTSVYGSVYAIADVAFCMGFAIGYSESG 449


>gi|42476325 solute carrier family 18 (vesicular monoamine), member
           2 [Homo sapiens]
          Length = 514

 Score =  582 bits (1499), Expect = e-166
 Identities = 304/513 (59%), Positives = 378/513 (73%), Gaps = 41/513 (7%)

Query: 11  RLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSSLHLGHAGSSP 70
           R L+E R SR+L+L +VF+ALLLDNML TVVVPI+P++LY +  K   ++  +  A    
Sbjct: 10  RWLQESRRSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYSI--KHEKNATEIQTARPVH 67

Query: 71  HALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISAHKNNCLQGTG 130
            A  S +F +IFS+++N+T+    +          T   +    T A SA  ++C     
Sbjct: 68  TASISDSFQSIFSYYDNSTMVTGNATRDLTLHQTATQHMV----TNA-SAVPSDCPSEDK 122

Query: 131 FLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTY 190
            L  E  +VG+LFASKA +QL+ NPF+G LTNRIGY IP+FAGF IMF+ST+MFAFS +Y
Sbjct: 123 DLLNENVQVGLLFASKATVQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSY 182

Query: 191 TLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVM 250
             L +AR+LQGIGSS SSVAG+GMLASVYTDD ERG  MG ALGGLA+G+LVG PFGSV+
Sbjct: 183 AFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVL 242

Query: 251 YEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDPYILVAA---- 306
           YEFVGK+APFL+LA L LLDGA+QL +LQPS+V PES KGTPL  LLKDPYIL+AA    
Sbjct: 243 YEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLKDPYILIAAGSIC 302

Query: 307 ----------------------------GLAFLPASVSYLIGTNLFGVLANKMGRWLCSL 338
                                       G+AFLPAS+SYLIGTN+FG+LA+KMGRWLC+L
Sbjct: 303 FANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCAL 362

Query: 339 IGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVY 398
           +GM++VG S+LC+P A NI+GLI PN G+G AIGMVDSSMMPIMG+LVDLRH SVYGSVY
Sbjct: 363 LGMIIVGVSILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVY 422

Query: 399 AIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRSPPAKEEKLAI 458
           AIADVAFCMG+AIGPS GGAI KAIGFPWLM I G+I+I++APLC++LRSPPAKEEK+AI
Sbjct: 423 AIADVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDILFAPLCFFLRSPPAKEEKMAI 482

Query: 459 L-SQDCPMETRMYATQKPTKEFPLGEDSDEEPD 490
           L   +CP++T+MY TQ   + +P+GED + E D
Sbjct: 483 LMDHNCPIKTKMY-TQNNIQSYPIGEDEESESD 514


>gi|118582257 vesicular acetylcholine transporter [Homo sapiens]
          Length = 532

 Score =  292 bits (748), Expect = 4e-79
 Identities = 175/474 (36%), Positives = 255/474 (53%), Gaps = 65/474 (13%)

Query: 13  LKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSSLHLGHAGSSPHA 72
           L+E R  R+LVLV+V VALLLDNML+ V+VPIVP ++            H+   G  P  
Sbjct: 25  LQEPRRQRRLVLVIVCVALLLDNMLYMVIVPIVPDYI-----------AHMRGGGEGP-- 71

Query: 73  LASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISAHKNNCLQGTGFL 132
                           T  V E         N +A T    A+   +    + L+     
Sbjct: 72  --------------TRTPEVWEPTLPLPTPANASAYTANTSASPTAAWPAGSALRPRYPT 117

Query: 133 EEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTL 192
           E E  ++GVLFASKA++QLLVNP  GP  +R+ Y +P+  G  +MF STV+FAF+  Y  
Sbjct: 118 ESEDVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVLFAFAEDYAT 177

Query: 193 LFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYE 252
           LF AR+LQG+GS+F+  +G+ M+A  Y ++ ER RA+G AL  ++ G LV  PFG ++YE
Sbjct: 178 LFAARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYE 237

Query: 253 FVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAK----GTPLFMLLKDPYILVAA-- 306
           F GK  PFL+LA ++L D  L L + +P   +  +      GTP+  L+ DPYI V A  
Sbjct: 238 FAGKRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGA 297

Query: 307 ------------------------------GLAFLPASVSYLIGTNLFGVLANKMG--RW 334
                                         G+A+LPA V +++G  L   LA +    +W
Sbjct: 298 LTTCNIPLAFLEPTIATWMKHTMAASEWEMGMAWLPAFVPHVLGVYLTVRLAARYPHLQW 357

Query: 335 LCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDLRHTSVY 394
           L   +G+ V+G S   VP   +   L+    GL   I +VD++++P +  LVD+RH SVY
Sbjct: 358 LYGALGLAVIGASSCIVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVY 417

Query: 395 GSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRS 448
           GSVYAIAD+++ + +A+GP   G IV ++GF  L +  G+ N++YAP+   LR+
Sbjct: 418 GSVYAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRN 471


>gi|16445357 hypothetical protein LOC116843 [Homo sapiens]
          Length = 456

 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 85/353 (24%), Positives = 144/353 (40%), Gaps = 64/353 (18%)

Query: 137 TRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTY------ 190
           T +G++F   A+ +LL +   G     IG      AG  +    T++F            
Sbjct: 70  TIIGMIFGCFALFELLASLVFGNYLVHIGAKFMFVAGMFVSGGVTILFGVLDRVPDGPVF 129

Query: 191 -TLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGL----ALGLLVGAP 245
             + F+ R +  +  + +  A   +LA  + ++      + T LG L     LGL++G P
Sbjct: 130 IAMCFLVRVMDAVSFAAAMTASSSILAKAFPNN------VATVLGSLETFSGLGLILGPP 183

Query: 246 FGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLK------- 298
            G  +Y+  G   PF++L  + LL   L + IL   +  P       L  L K       
Sbjct: 184 VGGFLYQSFGYEVPFIVLGCVVLLMVPLNMYILPNYESDPGEHSFWKLIALPKVGLIAFV 243

Query: 299 -----------DPYILVAA-----------GLAFLPASVSYLIGTNLFGVLANK---MGR 333
                      DP + +             GL FL  ++SY I + LFG+L++K   + +
Sbjct: 244 INSLSSCFGFLDPTLSLFVLEKFNLPAGYVGLVFLGMALSYAISSPLFGLLSDKRPPLRK 303

Query: 334 WLCSLIGMLVVGTSLLC--VPLAH---NIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL 388
           WL     ++  G  +L   VP+ H    ++ L+      GL+ GM   S++P    ++  
Sbjct: 304 WLLVFGNLITAGCYMLLGPVPILHIKSQLWLLVLILVVSGLSAGM---SIIPTFPEILSC 360

Query: 389 RHT-------SVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGV 434
            H        S  G V  +    + +G  +GP+ GG + + IGF W   I G+
Sbjct: 361 AHENGFEEGLSTLGLVSGLFSAMWSIGAFMGPTLGGFLYEKIGFEWAAAIQGL 413



 Score = 29.3 bits (64), Expect = 8.6
 Identities = 10/40 (25%), Positives = 22/40 (55%)

Query: 407 MGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYL 446
           +G  +GP  GG + ++ G+    ++ G + ++  PL  Y+
Sbjct: 176 LGLILGPPVGGFLYQSFGYEVPFIVLGCVVLLMVPLNMYI 215


>gi|24431958 solute carrier family 16, member 7 [Homo sapiens]
          Length = 478

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 4/127 (3%)

Query: 155 PFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVART-LQGIGSSFSSVAGLG 213
           P    L N+ G    + AG ++  L  V+ +FS +   L++    + G+G +F+    L 
Sbjct: 74  PVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALT 133

Query: 214 MLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLALLDGAL 273
           ++   +    +R  A G A+ G  + L   APF   ++   G    FLIL  L LL+  +
Sbjct: 134 IIGKYFY--RKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSL-LLNACV 190

Query: 274 QLCILQP 280
              +++P
Sbjct: 191 AGSLMRP 197


>gi|115583685 solute carrier family 16, member 1 [Homo sapiens]
          Length = 500

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 39/142 (27%), Positives = 59/142 (41%), Gaps = 7/142 (4%)

Query: 155 PFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVA-RTLQGIGSSFSSVAGLG 213
           P    L N+ G  I M  G  +     +  +F  T   L+V    + G+G +F+    L 
Sbjct: 74  PISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALT 133

Query: 214 MLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL---LD 270
           M+   +     R  A G A+ G  + L   AP   V +   G    FLIL  L L   + 
Sbjct: 134 MIGKYFYK--RRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVA 191

Query: 271 GALQLCI-LQPSKVSPESAKGT 291
           GAL   I  +P+K   + +K +
Sbjct: 192 GALMRPIGPKPTKAGKDKSKAS 213


>gi|109288010 solute carrier family 16, member 3 [Homo sapiens]
          Length = 465

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 76/309 (24%), Positives = 122/309 (39%), Gaps = 39/309 (12%)

Query: 131 FLEEEITRVGVLFASKAVMQLLVNPFV---GPL----TNRIGYHIPMFAGFVIMFLSTVM 183
           F +E I   G+ ++  A +  ++   +   GPL     NR G    M  G +   L  V 
Sbjct: 45  FFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVA 104

Query: 184 FAFSGTYTLLFVAR-TLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLV 242
            +F  +   +++    + G+G + +    L ML   ++    R  A G A  G  + L  
Sbjct: 105 ASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSK--RRPMANGLAAAGSPVFLCA 162

Query: 243 GAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDPYI 302
            +P G ++ +  G    FLIL  L LL+  +   +++P  V+ +   G P          
Sbjct: 163 LSPLGQLLQDRYGWRGGFLILGGL-LLNCCVCAALMRPLVVTAQPGSGPP---------- 211

Query: 303 LVAAGLAFLPASVSYLIGTNLFGVLANKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIG 362
                   L  SV    G  L+ V A+ M      ++G+ V    +  V  A ++ G+  
Sbjct: 212 --RPSRRLLDLSVFRDRGFVLYAVAASVM------VLGLFV--PPVFVVSYAKDL-GVPD 260

Query: 363 PNAGLGLAI-GMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFA-IGPST----G 416
             A   L I G +D    P  G +  L     Y SVY  +   F  G A +  ST    G
Sbjct: 261 TKAAFLLTILGFIDIFARPAAGFVAGLGKVRPY-SVYLFSFSMFFNGLADLAGSTAGDYG 319

Query: 417 GAIVKAIGF 425
           G +V  I F
Sbjct: 320 GLVVFCIFF 328


>gi|109288012 solute carrier family 16, member 3 [Homo sapiens]
          Length = 465

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 76/309 (24%), Positives = 122/309 (39%), Gaps = 39/309 (12%)

Query: 131 FLEEEITRVGVLFASKAVMQLLVNPFV---GPL----TNRIGYHIPMFAGFVIMFLSTVM 183
           F +E I   G+ ++  A +  ++   +   GPL     NR G    M  G +   L  V 
Sbjct: 45  FFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVA 104

Query: 184 FAFSGTYTLLFVAR-TLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLV 242
            +F  +   +++    + G+G + +    L ML   ++    R  A G A  G  + L  
Sbjct: 105 ASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSK--RRPMANGLAAAGSPVFLCA 162

Query: 243 GAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDPYI 302
            +P G ++ +  G    FLIL  L LL+  +   +++P  V+ +   G P          
Sbjct: 163 LSPLGQLLQDRYGWRGGFLILGGL-LLNCCVCAALMRPLVVTAQPGSGPP---------- 211

Query: 303 LVAAGLAFLPASVSYLIGTNLFGVLANKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIG 362
                   L  SV    G  L+ V A+ M      ++G+ V    +  V  A ++ G+  
Sbjct: 212 --RPSRRLLDLSVFRDRGFVLYAVAASVM------VLGLFV--PPVFVVSYAKDL-GVPD 260

Query: 363 PNAGLGLAI-GMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFA-IGPST----G 416
             A   L I G +D    P  G +  L     Y SVY  +   F  G A +  ST    G
Sbjct: 261 TKAAFLLTILGFIDIFARPAAGFVAGLGKVRPY-SVYLFSFSMFFNGLADLAGSTAGDYG 319

Query: 417 GAIVKAIGF 425
           G +V  I F
Sbjct: 320 GLVVFCIFF 328


>gi|4759112 solute carrier family 16, member 3 [Homo sapiens]
          Length = 465

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 76/309 (24%), Positives = 122/309 (39%), Gaps = 39/309 (12%)

Query: 131 FLEEEITRVGVLFASKAVMQLLVNPFV---GPL----TNRIGYHIPMFAGFVIMFLSTVM 183
           F +E I   G+ ++  A +  ++   +   GPL     NR G    M  G +   L  V 
Sbjct: 45  FFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVA 104

Query: 184 FAFSGTYTLLFVAR-TLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLV 242
            +F  +   +++    + G+G + +    L ML   ++    R  A G A  G  + L  
Sbjct: 105 ASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSK--RRPMANGLAAAGSPVFLCA 162

Query: 243 GAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDPYI 302
            +P G ++ +  G    FLIL  L LL+  +   +++P  V+ +   G P          
Sbjct: 163 LSPLGQLLQDRYGWRGGFLILGGL-LLNCCVCAALMRPLVVTAQPGSGPP---------- 211

Query: 303 LVAAGLAFLPASVSYLIGTNLFGVLANKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIG 362
                   L  SV    G  L+ V A+ M      ++G+ V    +  V  A ++ G+  
Sbjct: 212 --RPSRRLLDLSVFRDRGFVLYAVAASVM------VLGLFV--PPVFVVSYAKDL-GVPD 260

Query: 363 PNAGLGLAI-GMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFA-IGPST----G 416
             A   L I G +D    P  G +  L     Y SVY  +   F  G A +  ST    G
Sbjct: 261 TKAAFLLTILGFIDIFARPAAGFVAGLGKVRPY-SVYLFSFSMFFNGLADLAGSTAGDYG 319

Query: 417 GAIVKAIGF 425
           G +V  I F
Sbjct: 320 GLVVFCIFF 328


>gi|6912666 sialin [Homo sapiens]
          Length = 495

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 72/336 (21%), Positives = 130/336 (38%), Gaps = 50/336 (14%)

Query: 73  LASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISAHKNNCLQGTGFL 132
           LA   F  +++   N +VA+ + V S     ++  S   P  +  I  H N    G  + 
Sbjct: 45  LAFFGFFIVYALRVNLSVALVDMVDSNTTLEDNRTSKACPEHSAPIKVHHNQT--GKKYQ 102

Query: 133 EEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPM---FAGFVIMFLSTVMFAFSGT 189
            +  T+ G +  S     ++     G + ++IG  + +     G  ++ L T + A  G 
Sbjct: 103 WDAETQ-GWILGSFFYGYIITQIPGGYVASKIGGKMLLGFGILGTAVLTLFTPIAADLGV 161

Query: 190 YTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSV 249
             L+ V R L+G+G   +  A   M +S +    ER + +  +  G  LG ++  P   +
Sbjct: 162 GPLI-VLRALEGLGEGVTFPAMHAMWSS-WAPPLERSKLLSISYAGAQLGTVISLPLSGI 219

Query: 250 M---------YEFVGKSAPFLILAFLALLDGALQL----------CILQPSKVSPESAKG 290
           +         + F G    F  L ++ L+    Q            IL   +    S K 
Sbjct: 220 ICYYMNWTYVFYFFGTIGIFWFLLWIWLVSDTPQKHKRISHYEKEYILSSLRNQLSSQKS 279

Query: 291 TPLFMLLKDP--YILVAAGLAF----------LPASVSYLIGTNLF--GVLANK--MGRW 334
            P   +LK    + +V A  ++          LP  +  ++  N+   G L++   +G W
Sbjct: 280 VPWVPILKSLPLWAIVVAHFSYNWTFYTLLTLLPTYMKEILRFNVQENGFLSSLPYLGSW 339

Query: 335 LCSLIGMLVVGT-------SLLCVPLAHNIFGLIGP 363
           LC ++              S LCV    ++ G+IGP
Sbjct: 340 LCMILSGQAADNLRAKWNFSTLCVRRIFSLIGMIGP 375


>gi|4759116 solute carrier family 16, member 5 [Homo sapiens]
          Length = 505

 Score = 37.7 bits (86), Expect = 0.024
 Identities = 36/146 (24%), Positives = 64/146 (43%), Gaps = 10/146 (6%)

Query: 152 LVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYT-LLFVARTLQGIGSSFSSVA 210
           +  P    L  R G  + +  G V+  L  V  +FS   + L F A  + G+G  FS  +
Sbjct: 65  MAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQS 124

Query: 211 GLGMLASVYTDDHERGRAMGTALG--GLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL 268
            + +L   +     R R +  AL   G++LG+ +       + E +G    FL+   +  
Sbjct: 125 SITVLGFYFV----RRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGI-F 179

Query: 269 LDGALQLCILQP--SKVSPESAKGTP 292
           L   +   I++P  + V+PE+ +  P
Sbjct: 180 LHCCICGAIIRPVATSVAPETKECPP 205


>gi|225703102 major facilitator superfamily domain containing 10
           [Homo sapiens]
          Length = 455

 Score = 37.4 bits (85), Expect = 0.031
 Identities = 57/256 (22%), Positives = 98/256 (38%), Gaps = 61/256 (23%)

Query: 23  VLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSSLHLGHAGSSPHALASPAFSTIF 82
           V+ VVF+ LLLD + FT+++P++P  L      E +   H             P +    
Sbjct: 24  VVTVVFLGLLLDLLAFTLLLPLLPGLL------ESHGRAH------------DPLYG--- 62

Query: 83  SFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISAHKNNCLQGTGFLEEEITRVGVL 142
                       S   G+ W    A+ I  P    +    N+ L G           G++
Sbjct: 63  ------------SWQGGVDWF---ATAIGMP----VEKRYNSVLFG-----------GLI 92

Query: 143 FASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGI 202
            ++ +V+Q L  P  G  ++ +G    M    + +  S  ++A S ++     +R + GI
Sbjct: 93  GSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGI 152

Query: 203 GSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLI 262
                S++     A V        R+ G A+ G+A  L      G  +   +G S P  +
Sbjct: 153 SKGNVSLS----TAIVADLGSPLARSQGMAVIGVAFSL------GFTLGPMLGASLPLEM 202

Query: 263 LAFLALLDGALQLCIL 278
             + ALL  A  L  +
Sbjct: 203 APWFALLFAASDLLFI 218



 Score = 33.5 bits (75), Expect = 0.45
 Identities = 32/152 (21%), Positives = 62/152 (40%), Gaps = 6/152 (3%)

Query: 307 GLAFLPASVSYLIGTNLFGVLANKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAG 366
           GL     SV   +   L G  ++ +GR    L+ ++ V TS      + +    +     
Sbjct: 90  GLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLI 149

Query: 367 LGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFP 426
            G++ G V  S   +     DL          A+  VAF +GF +GP  G ++   +  P
Sbjct: 150 GGISKGNVSLSTAIV----ADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMA-P 204

Query: 427 WLMVITGVINIVYAPLCYYLRSPPAKEEKLAI 458
           W  ++    ++++   C+   + P ++   +I
Sbjct: 205 WFALLFAASDLLFI-FCFLPETLPLEKRAPSI 235


>gi|169217968 PREDICTED: similar to solute carrier family 16, member
           5 [Homo sapiens]
          Length = 453

 Score = 37.4 bits (85), Expect = 0.031
 Identities = 37/150 (24%), Positives = 66/150 (44%), Gaps = 10/150 (6%)

Query: 148 VMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYT-LLFVARTLQGIGSSF 206
           ++ L   P    L  R G  + +  G V+  L  V  +FS   + L F A  + G+G  F
Sbjct: 9   LVALSERPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCF 68

Query: 207 SSVAGLGMLASVYTDDHERGRAMGTALG--GLALGLLVGAPFGSVMYEFVGKSAPFLILA 264
           S  + + +L   +     R R +  AL   G++LG+ +       + E +G    FL+  
Sbjct: 69  SFQSSITVLGFYFV----RRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFG 124

Query: 265 FLALLDGALQLCILQP--SKVSPESAKGTP 292
            +  L   +   I++P  + V+PE+ +  P
Sbjct: 125 GI-FLHCCICGAIIRPVATSVAPETKECPP 153


>gi|225703104 major facilitator superfamily domain containing 10
           [Homo sapiens]
          Length = 455

 Score = 37.4 bits (85), Expect = 0.031
 Identities = 57/256 (22%), Positives = 98/256 (38%), Gaps = 61/256 (23%)

Query: 23  VLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSSLHLGHAGSSPHALASPAFSTIF 82
           V+ VVF+ LLLD + FT+++P++P  L      E +   H             P +    
Sbjct: 24  VVTVVFLGLLLDLLAFTLLLPLLPGLL------ESHGRAH------------DPLYG--- 62

Query: 83  SFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISAHKNNCLQGTGFLEEEITRVGVL 142
                       S   G+ W    A+ I  P    +    N+ L G           G++
Sbjct: 63  ------------SWQGGVDWF---ATAIGMP----VEKRYNSVLFG-----------GLI 92

Query: 143 FASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGI 202
            ++ +V+Q L  P  G  ++ +G    M    + +  S  ++A S ++     +R + GI
Sbjct: 93  GSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGI 152

Query: 203 GSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLI 262
                S++     A V        R+ G A+ G+A  L      G  +   +G S P  +
Sbjct: 153 SKGNVSLS----TAIVADLGSPLARSQGMAVIGVAFSL------GFTLGPMLGASLPLEM 202

Query: 263 LAFLALLDGALQLCIL 278
             + ALL  A  L  +
Sbjct: 203 APWFALLFAASDLLFI 218



 Score = 33.5 bits (75), Expect = 0.45
 Identities = 32/152 (21%), Positives = 62/152 (40%), Gaps = 6/152 (3%)

Query: 307 GLAFLPASVSYLIGTNLFGVLANKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAG 366
           GL     SV   +   L G  ++ +GR    L+ ++ V TS      + +    +     
Sbjct: 90  GLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLI 149

Query: 367 LGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFP 426
            G++ G V  S   +     DL          A+  VAF +GF +GP  G ++   +  P
Sbjct: 150 GGISKGNVSLSTAIV----ADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMA-P 204

Query: 427 WLMVITGVINIVYAPLCYYLRSPPAKEEKLAI 458
           W  ++    ++++   C+   + P ++   +I
Sbjct: 205 WFALLFAASDLLFI-FCFLPETLPLEKRAPSI 235


>gi|34916028 solute carrier family 16 (monocarboxylic acid
           transporters), member 9 [Homo sapiens]
          Length = 509

 Score = 36.6 bits (83), Expect = 0.054
 Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 3/119 (2%)

Query: 151 LLVNPFVGPLTNRIGYH-IPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGIGSSFSSV 209
           LL +P      +  G   + +F+GF++     +       Y L F    + G+G      
Sbjct: 63  LLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYT 122

Query: 210 AGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL 268
           A + +    + D   RG A+G    G ++GL + A    ++ EF G     LI+  LAL
Sbjct: 123 ATVTITCQYFDD--RRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALAL 179


>gi|4507021 solute carrier family 4, anion exchanger, member 1 [Homo
           sapiens]
          Length = 911

 Score = 35.4 bits (80), Expect = 0.12
 Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 13/83 (15%)

Query: 140 GVLFASKAVMQLLVNPFVGPL------------TNRIGYHIP-MFAGFVIMFLSTVMFAF 186
           G+LFA      LLV  F GPL            TN + Y +  ++ GF ++ L  ++ AF
Sbjct: 448 GILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAF 507

Query: 187 SGTYTLLFVARTLQGIGSSFSSV 209
            G++ + F++R  Q I S   S+
Sbjct: 508 EGSFLVRFISRYTQEIFSFLISL 530


>gi|21553331 solute carrier family 2 (facilitated glucose
           transporter), member 12 [Homo sapiens]
          Length = 617

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 25/101 (24%), Positives = 47/101 (46%), Gaps = 1/101 (0%)

Query: 141 VLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQ 200
           ++ +S  +  LL +   G L +R G    +     ++ L +++   S +YT+L V R   
Sbjct: 81  MVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAI 140

Query: 201 GIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLL 241
           G+  S SS+A    +A +    H RG  +      + +G+L
Sbjct: 141 GVSISLSSIATCVYIAEI-APQHRRGLLVSLNELMIVIGIL 180


>gi|156071474 solute carrier family 4, anion exchanger, member 2
           (erythrocyte membrane protein band 3-like 1) [Homo
           sapiens]
          Length = 1241

 Score = 34.7 bits (78), Expect = 0.20
 Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 13/109 (11%)

Query: 107 ASTIPPPATEAISAHKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPL------ 160
           A+  P      +   K   L G   L       GV+F       LLV  F GPL      
Sbjct: 718 AALSPAITFGGLLGEKTQDLIGVSELIMSTALQGVVFCLLGAQPLLVIGFSGPLLVFEEA 777

Query: 161 ------TNRIGYHIP-MFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGI 202
                 +N + Y +  ++ GF ++FL+ +M A  G++ + FV+R  Q I
Sbjct: 778 FFSFCSSNHLEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEI 826


>gi|213021148 SVOP-like isoform 1 [Homo sapiens]
          Length = 492

 Score = 33.5 bits (75), Expect = 0.45
 Identities = 25/122 (20%), Positives = 49/122 (40%), Gaps = 4/122 (3%)

Query: 317 YLIGTNLFGVLANKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDS 376
           Y++ + LFG+LA++ GRW   LI  L      L    A +    +     +G  +     
Sbjct: 97  YMVFSILFGLLADRYGRWKILLISFLWGAYFSLLTSFAPSYIWFVFLRTMVGCGVSGHSQ 156

Query: 377 SMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVIN 436
            ++       +   T   G +  ++ V +  G  +       I+  IG+ WL+ +  +  
Sbjct: 157 GLI----IKTEFLPTKYRGYMLPLSQVFWLAGSLLIIGLASVIIPTIGWRWLIRVASIPG 212

Query: 437 IV 438
           I+
Sbjct: 213 II 214


>gi|114796626 solute carrier family 16, member 8 [Homo sapiens]
          Length = 504

 Score = 33.1 bits (74), Expect = 0.59
 Identities = 31/115 (26%), Positives = 48/115 (41%), Gaps = 3/115 (2%)

Query: 155 PFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFV-ARTLQGIGSSFSSVAGLG 213
           P    L  R G    M AG ++     ++ +F+     L++ A  L G+G + +    L 
Sbjct: 73  PVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLI 132

Query: 214 MLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL 268
           ML   +  +  R  A G A  G  + L   +P G  + E  G    FL+L  L L
Sbjct: 133 MLGLYF--ERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLL 185


>gi|42542381 solute carrier family 28, member 1 isoform 1 [Homo
           sapiens]
          Length = 649

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 35/140 (25%), Positives = 60/140 (42%), Gaps = 9/140 (6%)

Query: 134 EEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLL 193
           E ++  G +F S+    LL+ P++  +T     H+ M  G+     +T+  +  G Y   
Sbjct: 307 ETLSVAGNIFVSQTEAPLLIRPYLADMT-LSEVHVVMTGGY-----ATIAGSLLGAYISF 360

Query: 194 FVARTLQGIGSSFSSVAGLGMLASVYTDDHER--GRAMGTALG-GLALGLLVGAPFGSVM 250
            +  T     S  ++   L +   VY +  E    R  G  L  G A  L+  A  G+ +
Sbjct: 361 GIDATSLIAASVMAAPCALALSKLVYPEVEESKFRREEGVKLTYGDAQNLIEAASTGAAI 420

Query: 251 YEFVGKSAPFLILAFLALLD 270
              V  +    ++AFLA+LD
Sbjct: 421 SVKVVANIAANLIAFLAVLD 440


>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
          Length = 613

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 37/159 (23%), Positives = 62/159 (38%), Gaps = 18/159 (11%)

Query: 338 LIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSV 397
           ++  L++G   + +PL  +  GLI     LGL  G   + M PI   LV        G +
Sbjct: 465 VLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELV--------GPM 516

Query: 398 YAIADVAFCMG-----FAIGPSTGGAIVKAIG-FPWLMVITGVINIVYAPLCYYLRSPPA 451
            A   + + +G        GP   G +    G +       GV  I+ A + +++   P 
Sbjct: 517 QASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAVILFFV---PL 573

Query: 452 KEEKLAILSQDCPMETRMYATQ-KPTKEFPLGEDSDEEP 489
             +++    Q    + +M A    P  E   G  + EEP
Sbjct: 574 MHQRMFKKEQRDSSKDKMLAPDPDPNGELLPGSPNPEEP 612



 Score = 30.8 bits (68), Expect = 2.9
 Identities = 26/92 (28%), Positives = 40/92 (43%), Gaps = 7/92 (7%)

Query: 149 MQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTL-LFVARTLQGIGSSFS 207
           M    +P V   T+R+G  I   AG  + F+     +F+ + +L  F    L G G SF+
Sbjct: 227 MIFFCSPIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFA 286

Query: 208 SVAGLGMLASVYTDDHERGRAMGTALGGLALG 239
               L +L       H   R +G A G ++ G
Sbjct: 287 FQPSLVILG------HYFQRRLGLANGVVSAG 312


>gi|4503847 solute carrier family 37 (glucose-6-phosphate
           transporter), member 4 [Homo sapiens]
          Length = 429

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 35/140 (25%), Positives = 62/140 (44%), Gaps = 17/140 (12%)

Query: 314 SVSYLIGTNLFGVLANKMG-RWLCSLIGMLVVGTSLL------CVPLAHNIFGLIGPNAG 366
           S +Y I   + GVL+++M  RWL S  G+L+VG   +       VP+   ++ L G   G
Sbjct: 57  SAAYAISKFVSGVLSDQMSARWLFSS-GLLLVGLVNIFFAWSSTVPVFAALWFLNGLAQG 115

Query: 367 LGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFP 426
           LG           P    L      S +G+ +AI   +  +   +GP     + ++  + 
Sbjct: 116 LGWP---------PCGKVLRKWFEPSQFGTWWAILSTSMNLAGGLGPILATILAQSYSWR 166

Query: 427 WLMVITGVINIVYAPLCYYL 446
             + ++G + +V + LC  L
Sbjct: 167 STLALSGALCVVVSFLCLLL 186


>gi|23510410 solute carrier family 22 member 1 isoform b [Homo
           sapiens]
          Length = 506

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 17/59 (28%), Positives = 31/59 (52%)

Query: 157 VGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGML 215
           VG   +R G  + +    ++  +S V+ AFS  Y  + + R LQG+ S  + +AG  ++
Sbjct: 166 VGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLI 224


>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
           sapiens]
          Length = 554

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 17/59 (28%), Positives = 31/59 (52%)

Query: 157 VGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGML 215
           VG   +R G  + +    ++  +S V+ AFS  Y  + + R LQG+ S  + +AG  ++
Sbjct: 166 VGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLI 224


>gi|166795299 solute carrier family 2 (facilitated glucose
           transporter), member 1 [Homo sapiens]
          Length = 492

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 38/145 (26%), Positives = 66/145 (45%), Gaps = 15/145 (10%)

Query: 157 VGPLTNRIGYHIPMFAGFVIMFLSTVMFAFS---GTYTLLFVARTLQGIGSSFSSVAGLG 213
           VG   NR G    M    ++ F+S V+  FS    ++ +L + R + G+    ++   + 
Sbjct: 83  VGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTT-GFVP 141

Query: 214 MLASVYTDDHERGRAMGTALG-GLALGLLVGAPFGSVMYEFVGKSAPFLILAFLALLDGA 272
           M     +    RG A+GT    G+ +G+L+   FG  +   +G    + +L  +  +   
Sbjct: 142 MYVGEVSPTALRG-ALGTLHQLGIVVGILIAQVFG--LDSIMGNKDLWPLLLSIIFIPAL 198

Query: 273 LQLCILQPSKVSPESAKGTPLFMLL 297
           LQ CI+ P    PES    P F+L+
Sbjct: 199 LQ-CIVLP--FCPES----PRFLLI 216


>gi|41327156 solute carrier family 16 (monocarboxylic acid
           transporters), member 14 [Homo sapiens]
          Length = 510

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 22/90 (24%), Positives = 37/90 (41%), Gaps = 3/90 (3%)

Query: 151 LLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVA-RTLQGIGSSFSSV 209
           L+V PF+G   N  G       G ++  L  V+ A++     LF+      G+GS  + +
Sbjct: 84  LIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLGSGMAYL 143

Query: 210 AGLGMLASVYTDDHERGRAMGTALGGLALG 239
             + M+   +     R  A G +  G   G
Sbjct: 144 PAVVMVGRYF--QKRRALAQGLSTTGTGFG 171


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.140    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,011,393
Number of Sequences: 37866
Number of extensions: 791390
Number of successful extensions: 2763
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 2707
Number of HSP's gapped (non-prelim): 68
length of query: 493
length of database: 18,247,518
effective HSP length: 106
effective length of query: 387
effective length of database: 14,233,722
effective search space: 5508450414
effective search space used: 5508450414
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.