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Search of human proteins with 21450761
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21450761 hypothetical protein LOC221908 [Homo sapiens]
(253 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21450761 hypothetical protein LOC221908 [Homo sapiens] 512 e-145
gi|73427803 lethal giant larvae homolog 2 isoform c [Homo sapiens] 44 2e-04
gi|62739161 lethal giant larvae homolog 2 isoform a [Homo sapiens] 44 2e-04
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 42 5e-04
gi|46391104 hypothetical protein LOC83541 [Homo sapiens] 42 5e-04
gi|108389127 hypothetical protein LOC83541 [Homo sapiens] 42 5e-04
gi|13937401 hypothetical protein LOC83541 [Homo sapiens] 42 5e-04
gi|110349719 titin isoform N2-A [Homo sapiens] 42 7e-04
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 41 9e-04
gi|150418009 transforming, acidic coiled-coil containing protein... 41 9e-04
gi|55749531 splicing factor 3B subunit 2 [Homo sapiens] 41 0.001
gi|78499633 phospholipase C, eta 2 [Homo sapiens] 40 0.001
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 40 0.001
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 40 0.001
gi|156523244 membrane-associated ring finger (C3HC4) 11 [Homo sa... 40 0.001
gi|44955929 calmodulin regulated spectrin-associated protein 1-l... 40 0.001
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 40 0.002
gi|224994221 SH3-domain binding protein 2 isoform b [Homo sapiens] 40 0.003
gi|224994219 SH3-domain binding protein 2 isoform c [Homo sapiens] 40 0.003
gi|170014705 SH3-domain binding protein 2 isoform a [Homo sapiens] 40 0.003
gi|170014703 SH3-domain binding protein 2 isoform a [Homo sapiens] 40 0.003
gi|195947401 doublesex and mab-3 related transcription factor 2 ... 40 0.003
gi|5729806 doublesex and mab-3 related transcription factor 2 is... 40 0.003
gi|153945850 doublesex and mab-3 related transcription factor 2 ... 40 0.003
gi|156416026 zinc finger protein 219 [Homo sapiens] 39 0.004
gi|156415998 zinc finger protein 219 [Homo sapiens] 39 0.004
gi|156415996 zinc finger protein 219 [Homo sapiens] 39 0.004
gi|38569493 potassium voltage-gated channel, subfamily H (eag-re... 38 0.007
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [... 38 0.007
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 38 0.007
>gi|21450761 hypothetical protein LOC221908 [Homo sapiens]
Length = 253
Score = 512 bits (1319), Expect = e-145
Identities = 253/253 (100%), Positives = 253/253 (100%)
Query: 1 MMMGCGESELKSADGEEAAAVPGPPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSP 60
MMMGCGESELKSADGEEAAAVPGPPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSP
Sbjct: 1 MMMGCGESELKSADGEEAAAVPGPPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSP 60
Query: 61 GRRKGRAERRGAARQRRQVRFRLTPPSPVRSEPQPAVPQELEMPVLKSSLALGLELRAAA 120
GRRKGRAERRGAARQRRQVRFRLTPPSPVRSEPQPAVPQELEMPVLKSSLALGLELRAAA
Sbjct: 61 GRRKGRAERRGAARQRRQVRFRLTPPSPVRSEPQPAVPQELEMPVLKSSLALGLELRAAA 120
Query: 121 GSHFDAAKAVEEQLRKSFQIRCGLEESVSEGLNVPRSKRLFRDLVSLQVPEEQVLNAALR 180
GSHFDAAKAVEEQLRKSFQIRCGLEESVSEGLNVPRSKRLFRDLVSLQVPEEQVLNAALR
Sbjct: 121 GSHFDAAKAVEEQLRKSFQIRCGLEESVSEGLNVPRSKRLFRDLVSLQVPEEQVLNAALR 180
Query: 181 EKLALLPPQARAPHPKEPPGPGPDMTILCDPETLFYESPHLTLDGLPPLRLQLRPRPSED 240
EKLALLPPQARAPHPKEPPGPGPDMTILCDPETLFYESPHLTLDGLPPLRLQLRPRPSED
Sbjct: 181 EKLALLPPQARAPHPKEPPGPGPDMTILCDPETLFYESPHLTLDGLPPLRLQLRPRPSED 240
Query: 241 TFLMHRTLRRWEA 253
TFLMHRTLRRWEA
Sbjct: 241 TFLMHRTLRRWEA 253
>gi|73427803 lethal giant larvae homolog 2 isoform c [Homo sapiens]
Length = 1020
Score = 43.5 bits (101), Expect = 2e-04
Identities = 43/157 (27%), Positives = 66/157 (42%), Gaps = 19/157 (12%)
Query: 88 PVRSEP--QPAVPQELEMPVLKSSLALGLELRAAAGSHFDAAKAVEEQLRKSFQIRCGLE 145
PVR EP QP V + + P + +SLAL E R A + Q R+ ++C L
Sbjct: 570 PVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLH 629
Query: 146 ESVSEGLNVPRSKRLFRDLVSLQVPEEQVLNAALREKLALLPPQARAPHPKEPPGPGPDM 205
S L P S+ + SL+ Q R +++ +R HP PPG +
Sbjct: 630 PSDQLALEGPLSR-----VKSLKKSLRQSFRRMRRSRVS-----SRKRHPAGPPGEAQEG 679
Query: 206 TILCDPETLFYESPHLTLDGLPPLRLQLRPRPSEDTF 242
+ E P L L P++ ++ R +ED+F
Sbjct: 680 SAKA-------ERPGLQNMELAPVQRKIEARSAEDSF 709
>gi|62739161 lethal giant larvae homolog 2 isoform a [Homo sapiens]
Length = 1015
Score = 43.5 bits (101), Expect = 2e-04
Identities = 43/157 (27%), Positives = 66/157 (42%), Gaps = 19/157 (12%)
Query: 88 PVRSEP--QPAVPQELEMPVLKSSLALGLELRAAAGSHFDAAKAVEEQLRKSFQIRCGLE 145
PVR EP QP V + + P + +SLAL E R A + Q R+ ++C L
Sbjct: 570 PVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLH 629
Query: 146 ESVSEGLNVPRSKRLFRDLVSLQVPEEQVLNAALREKLALLPPQARAPHPKEPPGPGPDM 205
S L P S+ + SL+ Q R +++ +R HP PPG +
Sbjct: 630 PSDQLALEGPLSR-----VKSLKKSLRQSFRRMRRSRVS-----SRKRHPAGPPGEAQEG 679
Query: 206 TILCDPETLFYESPHLTLDGLPPLRLQLRPRPSEDTF 242
+ E P L L P++ ++ R +ED+F
Sbjct: 680 SAKA-------ERPGLQNMELAPVQRKIEARSAEDSF 709
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 42.0 bits (97), Expect = 5e-04
Identities = 58/218 (26%), Positives = 78/218 (35%), Gaps = 22/218 (10%)
Query: 9 ELKSADGEEAAAVPGPPPEPQVPQLRAPVPEPGLD----LSLSPRPDSPQPRHGSPGRRK 64
E+ A +E A +P PP P P P+P P L P P P SP
Sbjct: 389 EMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPP 448
Query: 65 GRAERR-------GAARQRRQVRFRLTPPSPVRSEPQPAVPQELEMPVLKSSLALGLELR 117
+ E+ A R++ R LTP E A P+ P S A G
Sbjct: 449 AQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATG---- 504
Query: 118 AAAGSHFDAAKAVEEQLRKSFQIRCGLEESVS-EGLNVPRSKRLFRDLVSLQVPEEQVLN 176
G D+ + IR + VS V ++ R F D + P+ +V +
Sbjct: 505 ---GPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEV-S 560
Query: 177 AALREKLALLP--PQARAPHPKEPPGPGPDMTILCDPE 212
LR + P PQ AP P P P P T + PE
Sbjct: 561 PVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPE 598
Score = 36.6 bits (83), Expect = 0.022
Identities = 56/233 (24%), Positives = 80/233 (34%), Gaps = 32/233 (13%)
Query: 19 AAVPGPPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHG---SPGRRKGRAERRGAARQ 75
AAV P PEP P + P P PR G S G R GR RG
Sbjct: 243 AAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGG-- 300
Query: 76 RRQVRFRLTPPSPVRSEPQPAVPQELEMPVLKSSLALGLELRAAAGSHFDAAKAVEEQLR 135
+ F + S + V L+LGLE G H ++ + V ++
Sbjct: 301 ---LPFVIKFVSRAKK-------------VKMGQLSLGLESGQGQGQHEESWQDVPQRRV 344
Query: 136 KSFQIRCGLEESVSEGLNVPRSKRLFRDLVSLQVPE-------EQVLNAALREKLALLPP 188
S Q + + L+ ++ + + E E+++ AA +E+ L PP
Sbjct: 345 GSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPP 404
Query: 189 QARAPHPKEPPGPGPDMTI----LCDPETLFYESPHLTLDGLPPLRLQLRPRP 237
P P PP P T LC P P L PP + + P
Sbjct: 405 PLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESP 457
>gi|46391104 hypothetical protein LOC83541 [Homo sapiens]
Length = 295
Score = 42.0 bits (97), Expect = 5e-04
Identities = 47/159 (29%), Positives = 60/159 (37%), Gaps = 21/159 (13%)
Query: 20 AVPGPPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPGRRKGRAERRGAARQR--- 76
A+PGP PQ L + +DL SP SP +PGR +G A R
Sbjct: 92 ALPGPCRRPQ---LDLDILSSLIDLCDSPV--SPAEASRTPGRAEGAGRPPPATPPRPPP 146
Query: 77 -----RQVRFRLTPPSPVRSEPQPAVPQELEMPVLKSSLALGLELRAAAGSHFDAAKAVE 131
R+V R P SP R P P P SS A L+ + +
Sbjct: 147 STSAVRRVDVRPLPASPARPCPSPG-------PAAASSPARPPGLQRSKSDLSERFSRAA 199
Query: 132 EQLRKSFQIRCGLEESVSEGLNVPRSKRLFRDLVSLQVP 170
L + F CGL+ + GL V R D+VSL P
Sbjct: 200 ADLERFFNF-CGLDPEEARGLGVAHLARASSDIVSLAGP 237
>gi|108389127 hypothetical protein LOC83541 [Homo sapiens]
Length = 295
Score = 42.0 bits (97), Expect = 5e-04
Identities = 47/159 (29%), Positives = 60/159 (37%), Gaps = 21/159 (13%)
Query: 20 AVPGPPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPGRRKGRAERRGAARQR--- 76
A+PGP PQ L + +DL SP SP +PGR +G A R
Sbjct: 92 ALPGPCRRPQ---LDLDILSSLIDLCDSPV--SPAEASRTPGRAEGAGRPPPATPPRPPP 146
Query: 77 -----RQVRFRLTPPSPVRSEPQPAVPQELEMPVLKSSLALGLELRAAAGSHFDAAKAVE 131
R+V R P SP R P P P SS A L+ + +
Sbjct: 147 STSAVRRVDVRPLPASPARPCPSPG-------PAAASSPARPPGLQRSKSDLSERFSRAA 199
Query: 132 EQLRKSFQIRCGLEESVSEGLNVPRSKRLFRDLVSLQVP 170
L + F CGL+ + GL V R D+VSL P
Sbjct: 200 ADLERFFNF-CGLDPEEARGLGVAHLARASSDIVSLAGP 237
>gi|13937401 hypothetical protein LOC83541 [Homo sapiens]
Length = 295
Score = 42.0 bits (97), Expect = 5e-04
Identities = 47/159 (29%), Positives = 60/159 (37%), Gaps = 21/159 (13%)
Query: 20 AVPGPPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPGRRKGRAERRGAARQR--- 76
A+PGP PQ L + +DL SP SP +PGR +G A R
Sbjct: 92 ALPGPCRRPQ---LDLDILSSLIDLCDSPV--SPAEASRTPGRAEGAGRPPPATPPRPPP 146
Query: 77 -----RQVRFRLTPPSPVRSEPQPAVPQELEMPVLKSSLALGLELRAAAGSHFDAAKAVE 131
R+V R P SP R P P P SS A L+ + +
Sbjct: 147 STSAVRRVDVRPLPASPARPCPSPG-------PAAASSPARPPGLQRSKSDLSERFSRAA 199
Query: 132 EQLRKSFQIRCGLEESVSEGLNVPRSKRLFRDLVSLQVP 170
L + F CGL+ + GL V R D+VSL P
Sbjct: 200 ADLERFFNF-CGLDPEEARGLGVAHLARASSDIVSLAGP 237
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 41.6 bits (96), Expect = 7e-04
Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 23/94 (24%)
Query: 21 VPGPPPE-PQVPQLRAP------VPEPGLDLSLSPRPDSPQPRHGSPGRRKGRAERRGAA 73
VP PPP+ P+VP + P VPE + ++ P+P+SP P E
Sbjct: 10622 VPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEE----- 10676
Query: 74 RQRRQVRFRLTPPSPVRSEPQPAVPQELEMPVLK 107
PP+ V EP+PA P ++ +P K
Sbjct: 10677 -----------PPAEVVEEPEPAAPPQVTVPPKK 10699
Score = 34.7 bits (78), Expect = 0.082
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 8/86 (9%)
Query: 21 VPGPPPE-PQVPQLRAP------VPEPGLDLSLSPRPDSPQPRHGSPGRRKGRAERRGAA 73
VP PPP+ P+VP + P VPE + ++ P+P+SP P + ++ AA
Sbjct: 10538 VPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAA 10597
Query: 74 RQRR-QVRFRLTPPSPVRSEPQPAVP 98
++ +V P +P P+ VP
Sbjct: 10598 PPKKPEVTPVKVPEAPKEVVPEKKVP 10623
Score = 30.8 bits (68), Expect = 1.2
Identities = 23/87 (26%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
Query: 26 PEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPGRRKGRAERRGAARQRRQVRFRLTP 85
P +VP+++ V ++ R +SP P ++K ER+ R+ +V P
Sbjct: 9368 PPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEV----PP 9423
Query: 86 PSPVRSEPQPAVPQE---LEMPVLKSS 109
P V + P+ VP+E + +PV K +
Sbjct: 9424 PPKVPALPKKPVPEEKVAVPVPVAKKA 9450
Score = 30.4 bits (67), Expect = 1.5
Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 20/104 (19%)
Query: 16 EEAAAVPGP----PPEPQVPQL--------RAPVPEPGLDLSLSPR----PDSPQPRHGS 59
EE A VP P PP P+VP++ + PVP P + + P+ P P P
Sbjct: 9298 EEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKI 9357
Query: 60 P---GRRKGRAERRGAARQRRQV-RFRLTPPSPVRSEPQPAVPQ 99
P ++K + Q+ V ++T + P PAVP+
Sbjct: 9358 PVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPE 9401
Score = 28.9 bits (63), Expect = 4.5
Identities = 40/188 (21%), Positives = 69/188 (36%), Gaps = 15/188 (7%)
Query: 21 VPGPPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPGRRKGRAERRGA--ARQRRQ 78
VP P P L+ VPE + + + + P P+ ++ + R + R++ Q
Sbjct: 9803 VPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQ 9862
Query: 79 V-----RFRLTPPSPVRSEPQPAVPQELEMPVLKSSLALGLELRAAAGSHFDAAKAVEEQ 133
V + + P V E P +E+ PV + LE A E
Sbjct: 9863 VTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYL 9922
Query: 134 LRKSFQIRCGLEESVSEGLNVPRSKRLFRDLVSLQVPEEQVLNAALREKLALLPPQARAP 193
+ + + EE ++E VP ++ ++VPE +K +P + AP
Sbjct: 9923 VEEEEEYIHEEEEFITEEEVVP--------VIPVKVPEVPRKPVPEEKKPVPVPKKKEAP 9974
Query: 194 HPKEPPGP 201
K P P
Sbjct: 9975 PAKVPEVP 9982
Score = 28.9 bits (63), Expect = 4.5
Identities = 24/106 (22%), Positives = 38/106 (35%), Gaps = 25/106 (23%)
Query: 9 ELKSADGEEAAAVPGPPPEPQVPQLRAP--------VPEPGLDLSLSPRPDSPQPRHGSP 60
E K + + AVP PPP V ++ P +PEP + P P P
Sbjct: 10965 EPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPE---- 11020
Query: 61 GRRKGRAERRGAARQRRQVRFRLTPPSPVRSEPQPAVPQELEMPVL 106
+ + + + P PV EP P + + +PV+
Sbjct: 11021 ------------PKPKPEAEVKTIKPPPVEPEPTP-IAAPVTVPVV 11053
Score = 28.5 bits (62), Expect = 5.9
Identities = 22/90 (24%), Positives = 41/90 (45%), Gaps = 9/90 (10%)
Query: 16 EEAAAVPGPP--PEPQVPQLRAP---VPEPGLDLSLSPRPDSPQPRHGSPGRRKGRAERR 70
EE VP P P +VP++ P VPE + + + +P++P P+ + ++
Sbjct: 10479 EEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKV 10538
Query: 71 GAARQRRQVRFRLTPPSPVRSEPQPAVPQE 100
++ PP+ V P+ AVP++
Sbjct: 10539 PVPPPKKPE----VPPTKVPEVPKAAVPEK 10564
Score = 28.1 bits (61), Expect = 7.7
Identities = 33/127 (25%), Positives = 50/127 (39%), Gaps = 9/127 (7%)
Query: 14 DGEEAAAVPG--PPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQP-RHGSPGRRKGRAERR 70
DG +P PP P P+ R+P P + R SP P RH R RA
Sbjct: 242 DGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTP 301
Query: 71 GAARQRRQVRFRLTPPSPVRSEPQPAVPQELEMPVLKSSLALGLELRAAAGSHFDAAKAV 130
R T SP+RS P + ++ + S++A G E+ A +
Sbjct: 302 SPVRSVSPAARIST--SPIRSVRSPLLMRKTQ----ASTVATGPEVPPPWKQEGYVASSS 355
Query: 131 EEQLRKS 137
E ++R++
Sbjct: 356 EAEMRET 362
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 41.2 bits (95), Expect = 9e-04
Identities = 33/103 (32%), Positives = 42/103 (40%), Gaps = 10/103 (9%)
Query: 6 GESELKSADGEEAAAVPGPPPEPQVPQLR------APVPEPGLDLSLSPRPDSPQPRHGS 59
G + A G + PP +P P R A P P SP P S G
Sbjct: 316 GSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGR 375
Query: 60 PGRRKGRAERRGAARQRRQVRFRLTPPSP---VRSEPQPAVPQ 99
GR G A RR R+RR+ R R + +P R P+PA P+
Sbjct: 376 GGRAAGGAGRRRRRRRRRR-RSRSSASAPRRRGRRRPRPAPPR 417
Score = 29.6 bits (65), Expect = 2.6
Identities = 22/85 (25%), Positives = 32/85 (37%)
Query: 12 SADGEEAAAVPGPPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPGRRKGRAERRG 71
S+D PGP PEP + + + RP S P G+ GRR G +
Sbjct: 429 SSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSS 488
Query: 72 AARQRRQVRFRLTPPSPVRSEPQPA 96
+ R + SP +S + A
Sbjct: 489 SRSPGPHPRSWSSSRSPSKSRSRSA 513
>gi|150418009 transforming, acidic coiled-coil containing protein 2
isoform a [Homo sapiens]
Length = 2948
Score = 41.2 bits (95), Expect = 9e-04
Identities = 53/214 (24%), Positives = 80/214 (37%), Gaps = 23/214 (10%)
Query: 7 ESELKSADGEEAAAVPGPPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPGRRKGR 66
E + + DG+ + P P E P+L+ PE SPRP P P + R
Sbjct: 1782 ERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRP-GPSMLPSVPKKDAPR 1840
Query: 67 AERRGAARQRRQVRFRLTPPSPVRSEP-QPAVPQELEMPVLKSSLALGLELRAAAGSHFD 125
+ + + R T SPV + QPA P +LE P L AA+ H D
Sbjct: 1841 VMDKVTSDETRGAEG--TESSPVADDIIQPAAPADLESPTL-----------AASSYHGD 1887
Query: 126 AAKAVEEQL----RKSFQIRCGLEESVSEGL---NVPRSKRLFRDLVSLQVPEEQVLNAA 178
V L GL S +E + + P R+ S P + + ++
Sbjct: 1888 VVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRVEASTPSCPDPAKDLSRSS 1947
Query: 179 LREKLALLPPQARAPHPKEPPGPGPDMTILCDPE 212
E+ A P++ P P P P ++ +PE
Sbjct: 1948 DSEE-AFETPESTTPVKAPPAPPPPPPEVIPEPE 1980
>gi|55749531 splicing factor 3B subunit 2 [Homo sapiens]
Length = 895
Score = 40.8 bits (94), Expect = 0.001
Identities = 50/205 (24%), Positives = 80/205 (39%), Gaps = 29/205 (14%)
Query: 10 LKSADGEEAAAVPGPPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPGRRKGRAER 69
L+ DG++AA PP Q+P + P P GL P P P P PG G
Sbjct: 70 LRGEDGDKAAP---PPMSAQLPGIPMPPPPLGLPPLQPPPPPPPPP----PGLGLGFPMA 122
Query: 70 RGAARQRRQVRFRLTPPSPVRSEPQPAVPQELEMPVLKSSLALGLELRAAAGSHFDAA-- 127
L PP P+R A+ +E + + + AL ++ A D +
Sbjct: 123 HPP---------NLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQEERAKQQGDHSLK 173
Query: 128 --KAVEEQLRKSFQIRCGLEESVSE-GLNVPRSKRLFRDLVSLQV-----PEEQVLNAAL 179
+ +E+Q R + + ++ +++ G VPR +D+ + V P +
Sbjct: 174 EHELLEQQKRAAVLLEQERQQEIAKMGTPVPRPP---QDMGQIGVRTPLGPRVAAPVGPV 230
Query: 180 REKLALLPPQARAPHPKEPPGPGPD 204
+LP A P P+ PP P D
Sbjct: 231 GPTPTVLPMGAPVPRPRGPPPPPGD 255
>gi|78499633 phospholipase C, eta 2 [Homo sapiens]
Length = 1416
Score = 40.4 bits (93), Expect = 0.001
Identities = 66/237 (27%), Positives = 89/237 (37%), Gaps = 38/237 (16%)
Query: 16 EEAAAVPGPPPEPQVP----QLRAPVPE-PGLDLSLSPRPDSPQPRHGSPGRRKGRAERR 70
EE A PGPPP VP Q R P P PG +++ SP D+ +PR P R E
Sbjct: 1008 EEPAPGPGPPPPAAVPTSSSQGRPPYPTGPGANVA-SPLEDTEEPRDSRP--RPCNGEGA 1064
Query: 71 GAARQRRQVRFRLTPPSPVRSEPQPAVPQELEMPVLKSSLALGLELRAAAGSHFD----- 125
G A +R P S QP L PV++ + G G
Sbjct: 1065 GGAYER-------APGSQTDGRSQPRTLGHL--PVIRRVKSEGQVPTEPLGGWRPLAAPF 1115
Query: 126 AAKAVEEQLRKSFQI-----RCGLEESVSEGLNVPRSKRLFRDLVSLQVPEEQVLNAALR 180
A AV S + CG +SVS ++ S ++ L +P + R
Sbjct: 1116 PAPAVYSDATGSDPLWQRLEPCGHRDSVSSSSSMSSSD----TVIDLSLPSLGL--GRSR 1169
Query: 181 EKLALLPPQARAPHPKEPPGPGPDMTILCDPETLFYESPHLTLDG-LPPLRLQLRPR 236
E LA P P PD+ P T +P+L G PP+ +L+PR
Sbjct: 1170 ENLAGAHMGRLPPRPHSASAARPDL----PPVTKSKSNPNLRATGQRPPIPDELQPR 1222
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 40.4 bits (93), Expect = 0.001
Identities = 46/194 (23%), Positives = 69/194 (35%), Gaps = 24/194 (12%)
Query: 22 PGPPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPG-RRKGRAERRGAARQRRQVR 80
P PPP ++ + P PEP P +SP P+ G+ G RR+ +E G +
Sbjct: 786 PPPPPPKRLSSVSGPSPEP------PPLDESPGPKEGATGPRRRTLSEPAGPSEPPG--- 836
Query: 81 FRLTPPSPV--RSEPQPAVPQELEMPVLKSSLALGLELRAAAGSHFDAAKAVEEQLRKSF 138
PP+P S+ + P P + S GL +
Sbjct: 837 ----PPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRET 892
Query: 139 QIRCGLEESVSEGLNVPRSKRLFRDLVSLQVPEEQVLNAALREKLALLPPQARAPHPKEP 198
+ GL+ +++E V R + E + A L +A P AP P
Sbjct: 893 PVPPGLDFNLTESDTVKRRPKCRE--------REPLQTALLAFGVASATPGPAAPLPSPT 944
Query: 199 PGPGPDMTILCDPE 212
PG P + L PE
Sbjct: 945 PGESPPASSLPQPE 958
Score = 30.0 bits (66), Expect = 2.0
Identities = 22/66 (33%), Positives = 25/66 (37%), Gaps = 8/66 (12%)
Query: 12 SADGEEAAAVPGPPPEPQVPQLRAPVPEP------GLDLSLSPRP--DSPQPRHGSPGRR 63
SA AA +P P P P P PEP G+ L+P P P P PG
Sbjct: 931 SATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLE 990
Query: 64 KGRAER 69
A R
Sbjct: 991 SSAASR 996
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 40.4 bits (93), Expect = 0.001
Identities = 46/194 (23%), Positives = 69/194 (35%), Gaps = 24/194 (12%)
Query: 22 PGPPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPG-RRKGRAERRGAARQRRQVR 80
P PPP ++ + P PEP P +SP P+ G+ G RR+ +E G +
Sbjct: 868 PPPPPPKRLSSVSGPSPEP------PPLDESPGPKEGATGPRRRTLSEPAGPSEPPG--- 918
Query: 81 FRLTPPSPV--RSEPQPAVPQELEMPVLKSSLALGLELRAAAGSHFDAAKAVEEQLRKSF 138
PP+P S+ + P P + S GL +
Sbjct: 919 ----PPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRET 974
Query: 139 QIRCGLEESVSEGLNVPRSKRLFRDLVSLQVPEEQVLNAALREKLALLPPQARAPHPKEP 198
+ GL+ +++E V R + E + A L +A P AP P
Sbjct: 975 PVPPGLDFNLTESDTVKRRPKCRE--------REPLQTALLAFGVASATPGPAAPLPSPT 1026
Query: 199 PGPGPDMTILCDPE 212
PG P + L PE
Sbjct: 1027 PGESPPASSLPQPE 1040
Score = 30.0 bits (66), Expect = 2.0
Identities = 22/66 (33%), Positives = 25/66 (37%), Gaps = 8/66 (12%)
Query: 12 SADGEEAAAVPGPPPEPQVPQLRAPVPEP------GLDLSLSPRP--DSPQPRHGSPGRR 63
SA AA +P P P P P PEP G+ L+P P P P PG
Sbjct: 1013 SATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLE 1072
Query: 64 KGRAER 69
A R
Sbjct: 1073 SSAASR 1078
>gi|156523244 membrane-associated ring finger (C3HC4) 11 [Homo
sapiens]
Length = 402
Score = 40.4 bits (93), Expect = 0.001
Identities = 30/91 (32%), Positives = 39/91 (42%), Gaps = 6/91 (6%)
Query: 4 GCGESELKSADGEEAAAVPGPPPEPQ-VPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPGR 62
G G S + A+ +A P PPP P P P P P L P P SP+ +P R
Sbjct: 6 GHGGSRCRGAESGDAEPPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPE----TPER 61
Query: 63 RKGRAERRGAARQRRQVRFRLTPPSPVRSEP 93
G +E G R + L PP P+ +P
Sbjct: 62 AAGPSEPLGEVAPRCRGADEL-PPPPLPLQP 91
>gi|44955929 calmodulin regulated spectrin-associated protein 1-like 1
[Homo sapiens]
Length = 1478
Score = 40.4 bits (93), Expect = 0.001
Identities = 48/191 (25%), Positives = 79/191 (41%), Gaps = 28/191 (14%)
Query: 22 PGPPPEPQVPQLRAPVPEPGLDLSLSP-RPDSPQPRHGSPGRRKGRAERRGAARQRRQ-- 78
P P P+ Q+ + P + GL +++P DSP+P H SP ++ QR
Sbjct: 922 PQPSPQKQIRDFK-PSKQAGLSSAIAPFSSDSPRPTHPSPQSSNRKSASFSVKSQRTPRP 980
Query: 79 -------VRFRLTPPSPVRSEPQPAVPQELEMPV-LKSSLALGLELRAAAGSHFDAAKAV 130
+ LTPP V S P+ ++P+ +S + G + +K
Sbjct: 981 NELKITPLNRTLTPPRSVDSLPRLRRFSPSQVPIQTRSFVCFGDD----GEPQLKESKPK 1036
Query: 131 EEQLRKSFQIRCGLEESVSEGLNVPRSKRL--FRDLVSLQVPEEQVLNAALREKLALLPP 188
EE ++ + + LE+ G N P K + F VS +VL+ + E + L P
Sbjct: 1037 EEVKKEELESKGTLEQ---RGHN-PEEKEIKPFESTVS------EVLSLPVTETVCLTPN 1086
Query: 189 QARAPHPKEPP 199
+ + P EPP
Sbjct: 1087 EDQLNQPTEPP 1097
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 40.0 bits (92), Expect = 0.002
Identities = 55/211 (26%), Positives = 71/211 (33%), Gaps = 29/211 (13%)
Query: 18 AAAVPGPPPEPQVPQLRAPVPE-PGLDLSLSPRPDSP-QPRHGSPGRRKGRAERRGAARQ 75
AAAVP P EP P P PE P + P P+ P P P +
Sbjct: 1095 AAAVP-TPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTP 1153
Query: 76 RRQVRFRLTPPSPVRS-EPQPAVPQELEMPVLKSSLALGLELRAAAGSHFDAAKAVEEQL 134
+ P+P S P AVP E + +A E + A S A V
Sbjct: 1154 EESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVAT-- 1211
Query: 135 RKSFQIRCGLEESVSEGLNVPRSKRLFRDLVSLQVPEEQVLNAALREKLA---------- 184
LEE S +VP S+ ++ PEE AA L
Sbjct: 1212 ---------LEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVL 1262
Query: 185 ----LLPPQARAPHPKEPPGPGPDMTILCDP 211
L P A P P+EP P ++ L +P
Sbjct: 1263 TPEELSSPAASVPTPEEPASPAAAVSNLEEP 1293
Score = 31.6 bits (70), Expect = 0.69
Identities = 47/185 (25%), Positives = 62/185 (33%), Gaps = 16/185 (8%)
Query: 18 AAAVPGPPPEPQVPQLRAPVP-EPGLDLSLSPRPDSP-QPRHGSPGRRKGRAERRGAARQ 75
AAAVP PP EP P P P EP + P P+ P P P + +
Sbjct: 1030 AAAVP-PPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1088
Query: 76 RRQVRFRLTPPSPVRSEPQPAVPQE----LEMPVLKSSLALGLELRAAAGSHFDAAKAVE 131
P SP + P P P + P +S A + S A E
Sbjct: 1089 EE-------PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPE 1141
Query: 132 EQLRKSFQIRCGLEESVSEGLNVPRSKRLFRDLVSLQVPEEQVLNAALREKL-ALLPPQA 190
E + + EES S + VP + ++ P E AA+ L P A
Sbjct: 1142 EPAFPAPAVPTP-EESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAA 1200
Query: 191 RAPHP 195
P P
Sbjct: 1201 SVPTP 1205
Score = 29.6 bits (65), Expect = 2.6
Identities = 46/190 (24%), Positives = 59/190 (31%), Gaps = 31/190 (16%)
Query: 16 EEAAAVPGPPPEPQVPQLRAPVP-EPGLDLSLSPRPDSPQPRHGSPGRRKGRAERRGAAR 74
+ AA P EP P P P EP + P P+ P SP E
Sbjct: 988 DTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPT----SPAAAVPPPEE----- 1038
Query: 75 QRRQVRFRLTPPSPVRSEPQPAVPQELEMPVLKSSLALGLELRAAAGSHFDAAKAVEEQL 134
P SP + P P P +S A + S A EE
Sbjct: 1039 ----------PTSPAAAVPTPEEP---------TSPAAAVPTPEEPTSPAAAVPTPEEPT 1079
Query: 135 RKSFQIRCGLEESVSEGLNVPRSKRLFRDLVSLQVPEEQVL-NAALREKLALLPPQARAP 193
+ + EE S VP + ++ PEE AA+ P A P
Sbjct: 1080 SPAAAVPTP-EEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP 1138
Query: 194 HPKEPPGPGP 203
P+EP P P
Sbjct: 1139 TPEEPAFPAP 1148
>gi|224994221 SH3-domain binding protein 2 isoform b [Homo sapiens]
Length = 618
Score = 39.7 bits (91), Expect = 0.003
Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 3/73 (4%)
Query: 9 ELKSADGEEAAAVPG---PPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPGRRKG 65
++ D AA+PG PP P+ P L+ PVPE ++ PRP+ PQ H G
Sbjct: 418 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG 477
Query: 66 RAERRGAARQRRQ 78
++ R + + RQ
Sbjct: 478 QSFRSFSFEKPRQ 490
Score = 29.3 bits (64), Expect = 3.4
Identities = 55/226 (24%), Positives = 78/226 (34%), Gaps = 27/226 (11%)
Query: 16 EEAAAVPGPPPEPQVPQLRAP----VPEPGLDLSLSPRP--DSPQPRHGSPGRRKGRAE- 68
E+A P P P VP R P +P S P P P P+HG P +
Sbjct: 252 EDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDS 311
Query: 69 RRGAARQRRQVRFRLTPPSPVR-SEP----QPAVPQELEMPVLKSSLALGLE-------- 115
+R RR P +P R S+P P P + P + S + E
Sbjct: 312 KRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGA 371
Query: 116 LRAAAGSHFDAAKAVEEQLRKSFQIRCGLEESVSEGLNVPRSKRLFRDLVSLQVPEEQVL 175
++ + A + KSF + SE VP +K F + P E +
Sbjct: 372 CSTSSAAIMATATSRNCDKLKSFHLS-PRGPPTSEPPPVPANKPKFLKIAEEDPPREAAM 430
Query: 176 NAALREKLALLPPQARAPHPKEPPGPGPDMTILCDPETLFYESPHL 221
+A PP + P P+ P +L PE + PHL
Sbjct: 431 PGLFVPPVAPRPPALKLPVPEAMARP----AVLPRPEK--PQLPHL 470
>gi|224994219 SH3-domain binding protein 2 isoform c [Homo sapiens]
Length = 589
Score = 39.7 bits (91), Expect = 0.003
Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 3/73 (4%)
Query: 9 ELKSADGEEAAAVPG---PPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPGRRKG 65
++ D AA+PG PP P+ P L+ PVPE ++ PRP+ PQ H G
Sbjct: 389 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG 448
Query: 66 RAERRGAARQRRQ 78
++ R + + RQ
Sbjct: 449 QSFRSFSFEKPRQ 461
Score = 29.3 bits (64), Expect = 3.4
Identities = 55/226 (24%), Positives = 78/226 (34%), Gaps = 27/226 (11%)
Query: 16 EEAAAVPGPPPEPQVPQLRAP----VPEPGLDLSLSPRP--DSPQPRHGSPGRRKGRAE- 68
E+A P P P VP R P +P S P P P P+HG P +
Sbjct: 223 EDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDS 282
Query: 69 RRGAARQRRQVRFRLTPPSPVR-SEP----QPAVPQELEMPVLKSSLALGLE-------- 115
+R RR P +P R S+P P P + P + S + E
Sbjct: 283 KRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGA 342
Query: 116 LRAAAGSHFDAAKAVEEQLRKSFQIRCGLEESVSEGLNVPRSKRLFRDLVSLQVPEEQVL 175
++ + A + KSF + SE VP +K F + P E +
Sbjct: 343 CSTSSAAIMATATSRNCDKLKSFHLS-PRGPPTSEPPPVPANKPKFLKIAEEDPPREAAM 401
Query: 176 NAALREKLALLPPQARAPHPKEPPGPGPDMTILCDPETLFYESPHL 221
+A PP + P P+ P +L PE + PHL
Sbjct: 402 PGLFVPPVAPRPPALKLPVPEAMARP----AVLPRPEK--PQLPHL 441
>gi|170014705 SH3-domain binding protein 2 isoform a [Homo sapiens]
Length = 561
Score = 39.7 bits (91), Expect = 0.003
Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 3/73 (4%)
Query: 9 ELKSADGEEAAAVPG---PPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPGRRKG 65
++ D AA+PG PP P+ P L+ PVPE ++ PRP+ PQ H G
Sbjct: 361 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG 420
Query: 66 RAERRGAARQRRQ 78
++ R + + RQ
Sbjct: 421 QSFRSFSFEKPRQ 433
Score = 29.3 bits (64), Expect = 3.4
Identities = 55/226 (24%), Positives = 78/226 (34%), Gaps = 27/226 (11%)
Query: 16 EEAAAVPGPPPEPQVPQLRAP----VPEPGLDLSLSPRP--DSPQPRHGSPGRRKGRAE- 68
E+A P P P VP R P +P S P P P P+HG P +
Sbjct: 195 EDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDS 254
Query: 69 RRGAARQRRQVRFRLTPPSPVR-SEP----QPAVPQELEMPVLKSSLALGLE-------- 115
+R RR P +P R S+P P P + P + S + E
Sbjct: 255 KRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGA 314
Query: 116 LRAAAGSHFDAAKAVEEQLRKSFQIRCGLEESVSEGLNVPRSKRLFRDLVSLQVPEEQVL 175
++ + A + KSF + SE VP +K F + P E +
Sbjct: 315 CSTSSAAIMATATSRNCDKLKSFHLS-PRGPPTSEPPPVPANKPKFLKIAEEDPPREAAM 373
Query: 176 NAALREKLALLPPQARAPHPKEPPGPGPDMTILCDPETLFYESPHL 221
+A PP + P P+ P +L PE + PHL
Sbjct: 374 PGLFVPPVAPRPPALKLPVPEAMARP----AVLPRPEK--PQLPHL 413
>gi|170014703 SH3-domain binding protein 2 isoform a [Homo sapiens]
Length = 561
Score = 39.7 bits (91), Expect = 0.003
Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 3/73 (4%)
Query: 9 ELKSADGEEAAAVPG---PPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPGRRKG 65
++ D AA+PG PP P+ P L+ PVPE ++ PRP+ PQ H G
Sbjct: 361 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG 420
Query: 66 RAERRGAARQRRQ 78
++ R + + RQ
Sbjct: 421 QSFRSFSFEKPRQ 433
Score = 29.3 bits (64), Expect = 3.4
Identities = 55/226 (24%), Positives = 78/226 (34%), Gaps = 27/226 (11%)
Query: 16 EEAAAVPGPPPEPQVPQLRAP----VPEPGLDLSLSPRP--DSPQPRHGSPGRRKGRAE- 68
E+A P P P VP R P +P S P P P P+HG P +
Sbjct: 195 EDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDS 254
Query: 69 RRGAARQRRQVRFRLTPPSPVR-SEP----QPAVPQELEMPVLKSSLALGLE-------- 115
+R RR P +P R S+P P P + P + S + E
Sbjct: 255 KRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGA 314
Query: 116 LRAAAGSHFDAAKAVEEQLRKSFQIRCGLEESVSEGLNVPRSKRLFRDLVSLQVPEEQVL 175
++ + A + KSF + SE VP +K F + P E +
Sbjct: 315 CSTSSAAIMATATSRNCDKLKSFHLS-PRGPPTSEPPPVPANKPKFLKIAEEDPPREAAM 373
Query: 176 NAALREKLALLPPQARAPHPKEPPGPGPDMTILCDPETLFYESPHL 221
+A PP + P P+ P +L PE + PHL
Sbjct: 374 PGLFVPPVAPRPPALKLPVPEAMARP----AVLPRPEK--PQLPHL 413
>gi|195947401 doublesex and mab-3 related transcription factor 2
isoform 1 [Homo sapiens]
Length = 226
Score = 39.7 bits (91), Expect = 0.003
Identities = 29/79 (36%), Positives = 35/79 (44%), Gaps = 5/79 (6%)
Query: 4 GCGESELKSADGEEAAAVPGPPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPGRR 63
G E + DGEEA A PG P +P+ Q P P P L SP P+ R G
Sbjct: 54 GVDEDAEEEGDGEEAGASPGMPGQPE--QRGGPQPRPPLAPQASPAGTGPRERCTPAG-- 109
Query: 64 KGRAERRGAARQRRQVRFR 82
G AE R +R + R R
Sbjct: 110 -GGAEPRKLSRTPKCARCR 127
>gi|5729806 doublesex and mab-3 related transcription factor 2
isoform 1 [Homo sapiens]
Length = 226
Score = 39.7 bits (91), Expect = 0.003
Identities = 29/79 (36%), Positives = 35/79 (44%), Gaps = 5/79 (6%)
Query: 4 GCGESELKSADGEEAAAVPGPPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPGRR 63
G E + DGEEA A PG P +P+ Q P P P L SP P+ R G
Sbjct: 54 GVDEDAEEEGDGEEAGASPGMPGQPE--QRGGPQPRPPLAPQASPAGTGPRERCTPAG-- 109
Query: 64 KGRAERRGAARQRRQVRFR 82
G AE R +R + R R
Sbjct: 110 -GGAEPRKLSRTPKCARCR 127
>gi|153945850 doublesex and mab-3 related transcription factor 2
isoform 2 [Homo sapiens]
Length = 561
Score = 39.7 bits (91), Expect = 0.003
Identities = 29/79 (36%), Positives = 35/79 (44%), Gaps = 5/79 (6%)
Query: 4 GCGESELKSADGEEAAAVPGPPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPGRR 63
G E + DGEEA A PG P +P+ Q P P P L SP P+ R G
Sbjct: 54 GVDEDAEEEGDGEEAGASPGMPGQPE--QRGGPQPRPPLAPQASPAGTGPRERCTPAG-- 109
Query: 64 KGRAERRGAARQRRQVRFR 82
G AE R +R + R R
Sbjct: 110 -GGAEPRKLSRTPKCARCR 127
>gi|156416026 zinc finger protein 219 [Homo sapiens]
Length = 722
Score = 38.9 bits (89), Expect = 0.004
Identities = 49/189 (25%), Positives = 62/189 (32%), Gaps = 38/189 (20%)
Query: 16 EEAAAVPGPPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPGRRKGRAERRGAARQ 75
+ + A PGPPPEP P R P+ G SPQP G R GA
Sbjct: 552 QRSGAGPGPPPEPPPPSQRGSAPQSG-------AKPSPQPATWVEGASSPRPPSSGAGPG 604
Query: 76 RRQVRFRLTPPSPVRSEPQPAVPQELEMPVLKSSLALGLELRAAAGSHFDAAKAVEEQLR 135
R+ P SP R+ L + L L LRA G A+ L
Sbjct: 605 SRR-----KPASPGRT---------LRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLF 650
Query: 136 KSFQIRCGLEESVSEGLNVPRSKRLFRDLVSLQVPEEQVLNAALREKLALLPPQARAPHP 195
F G E ++ L V S+R + PP AR P
Sbjct: 651 CPF--ATGAPELMALHLQVHHSRR---------------ARGRRPPQADASPPYARVPSG 693
Query: 196 KEPPGPGPD 204
+ PP P +
Sbjct: 694 ETPPSPSQE 702
Score = 30.0 bits (66), Expect = 2.0
Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 4/42 (9%)
Query: 22 PGPPPEPQ---VPQLRAPVPEPGLDLSLSPRPDSPQPRHGSP 60
P PPP+P+ VPQ P PEP + + +P P +P+ P
Sbjct: 232 PQPPPQPEPRSVPQ-PEPEPEPEREATPTPAPAAPEEPPAPP 272
>gi|156415998 zinc finger protein 219 [Homo sapiens]
Length = 722
Score = 38.9 bits (89), Expect = 0.004
Identities = 49/189 (25%), Positives = 62/189 (32%), Gaps = 38/189 (20%)
Query: 16 EEAAAVPGPPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPGRRKGRAERRGAARQ 75
+ + A PGPPPEP P R P+ G SPQP G R GA
Sbjct: 552 QRSGAGPGPPPEPPPPSQRGSAPQSG-------AKPSPQPATWVEGASSPRPPSSGAGPG 604
Query: 76 RRQVRFRLTPPSPVRSEPQPAVPQELEMPVLKSSLALGLELRAAAGSHFDAAKAVEEQLR 135
R+ P SP R+ L + L L LRA G A+ L
Sbjct: 605 SRR-----KPASPGRT---------LRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLF 650
Query: 136 KSFQIRCGLEESVSEGLNVPRSKRLFRDLVSLQVPEEQVLNAALREKLALLPPQARAPHP 195
F G E ++ L V S+R + PP AR P
Sbjct: 651 CPF--ATGAPELMALHLQVHHSRR---------------ARGRRPPQADASPPYARVPSG 693
Query: 196 KEPPGPGPD 204
+ PP P +
Sbjct: 694 ETPPSPSQE 702
Score = 30.0 bits (66), Expect = 2.0
Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 4/42 (9%)
Query: 22 PGPPPEPQ---VPQLRAPVPEPGLDLSLSPRPDSPQPRHGSP 60
P PPP+P+ VPQ P PEP + + +P P +P+ P
Sbjct: 232 PQPPPQPEPRSVPQ-PEPEPEPEREATPTPAPAAPEEPPAPP 272
>gi|156415996 zinc finger protein 219 [Homo sapiens]
Length = 722
Score = 38.9 bits (89), Expect = 0.004
Identities = 49/189 (25%), Positives = 62/189 (32%), Gaps = 38/189 (20%)
Query: 16 EEAAAVPGPPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPGRRKGRAERRGAARQ 75
+ + A PGPPPEP P R P+ G SPQP G R GA
Sbjct: 552 QRSGAGPGPPPEPPPPSQRGSAPQSG-------AKPSPQPATWVEGASSPRPPSSGAGPG 604
Query: 76 RRQVRFRLTPPSPVRSEPQPAVPQELEMPVLKSSLALGLELRAAAGSHFDAAKAVEEQLR 135
R+ P SP R+ L + L L LRA G A+ L
Sbjct: 605 SRR-----KPASPGRT---------LRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLF 650
Query: 136 KSFQIRCGLEESVSEGLNVPRSKRLFRDLVSLQVPEEQVLNAALREKLALLPPQARAPHP 195
F G E ++ L V S+R + PP AR P
Sbjct: 651 CPF--ATGAPELMALHLQVHHSRR---------------ARGRRPPQADASPPYARVPSG 693
Query: 196 KEPPGPGPD 204
+ PP P +
Sbjct: 694 ETPPSPSQE 702
Score = 30.0 bits (66), Expect = 2.0
Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 4/42 (9%)
Query: 22 PGPPPEPQ---VPQLRAPVPEPGLDLSLSPRPDSPQPRHGSP 60
P PPP+P+ VPQ P PEP + + +P P +P+ P
Sbjct: 232 PQPPPQPEPRSVPQ-PEPEPEPEREATPTPAPAAPEEPPAPP 272
>gi|38569493 potassium voltage-gated channel, subfamily H
(eag-related), member 3 [Homo sapiens]
Length = 1083
Score = 38.1 bits (87), Expect = 0.007
Identities = 32/95 (33%), Positives = 37/95 (38%), Gaps = 15/95 (15%)
Query: 9 ELKSADGEEAAAV-PGPPPEPQVPQLRAPVPEPGLDLS------LSPRPDSPQPR---HG 58
E K DGE+ V P P EP P L PG S LSPR +P+PR G
Sbjct: 729 EEKETDGEQGPTVSPAPADEPSSPLL-----SPGCTSSSSAAKLLSPRRTAPRPRLGGRG 783
Query: 59 SPGRRKGRAERRGAARQRRQVRFRLTPPSPVRSEP 93
PGR G + R + PP P P
Sbjct: 784 RPGRAGALKAEAGPSAPPRALEGLRLPPMPWNVPP 818
>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [Homo
sapiens]
Length = 2564
Score = 38.1 bits (87), Expect = 0.007
Identities = 30/87 (34%), Positives = 39/87 (44%), Gaps = 7/87 (8%)
Query: 16 EEAAAVPGPPPEPQVPQLRAPVP---EPGLDL-SLSPRPDSPQPRHGSPGRRKGRAERRG 71
+E A PG P P +PQ R P GL+L +PRPD P+ R RR+ R G
Sbjct: 2331 QEKEAGPGLPAGPSLPQPRELPPGRLPNGLELPERTPRPDRPRARDRPKPRRRPRPREGG 2390
Query: 72 AARQRRQVRFRLTPPSPVRSEPQPAVP 98
R+ R + P+ S P P P
Sbjct: 2391 EGGGSRRSR---SAPAQGGSAPAPPPP 2414
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 38.1 bits (87), Expect = 0.007
Identities = 36/136 (26%), Positives = 54/136 (39%), Gaps = 11/136 (8%)
Query: 8 SELKSADGEEAAAVPGPPPEPQVPQLRAPVPEPGLDLSLSPRPDSPQPRHGSPGRRKGRA 67
+E +SA A P P P P PQ P E D ++ P +P P G
Sbjct: 535 NEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTT 594
Query: 68 ERRGAAR----QRRQVRFRLTPPSPVRSEPQPAVPQELEMPVLKSSLALGLELRAAAGSH 123
+R A R +RRQ R R E + + E + + + LA E RA +
Sbjct: 595 DREEATRLLAEKRRQAR-----EQREREEQERRLQAERDKRMREEQLAREAEARAEREA- 648
Query: 124 FDAAKAVEEQLRKSFQ 139
+A + E++ R+ Q
Sbjct: 649 -EARRREEQEAREKAQ 663
Score = 35.0 bits (79), Expect = 0.063
Identities = 26/87 (29%), Positives = 36/87 (41%), Gaps = 18/87 (20%)
Query: 35 APVPEPGLDLSLSPRPDSPQPRHGSPGRRKGRAE-----------------RRGAARQRR 77
+P P PG +L P+P SP+ SP R R E +R A+ ++
Sbjct: 479 SPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKE 538
Query: 78 QVRFRLTPPSPVRSEPQPAVPQELEMP 104
PSP S P PA PQ+ + P
Sbjct: 539 SAAPASPAPSPAPS-PTPAPPQKEQPP 564
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.135 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,027,180
Number of Sequences: 37866
Number of extensions: 957335
Number of successful extensions: 11185
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 130
Number of HSP's successfully gapped in prelim test: 647
Number of HSP's that attempted gapping in prelim test: 8244
Number of HSP's gapped (non-prelim): 3166
length of query: 253
length of database: 18,247,518
effective HSP length: 100
effective length of query: 153
effective length of database: 14,460,918
effective search space: 2212520454
effective search space used: 2212520454
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.