Search of human proteins with 213972566

Search of human proteins with 213972566

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|213972566 dachshund 2 isoform b [Homo sapiens]
         (571 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|213972566 dachshund 2 isoform b [Homo sapiens]                    1128   0.0  
gi|16876441 dachshund 2 isoform a [Homo sapiens]                     1117   0.0  
gi|213972568 dachshund 2 isoform c [Homo sapiens]                     800   0.0  
gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]              568   e-162
gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]              265   8e-71
gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]              229   5e-60
gi|239757043 PREDICTED: functional smad suppressing element 18 [...    63   8e-10
gi|239751555 PREDICTED: functional smad suppressing element 18 [...    63   8e-10
gi|239746067 PREDICTED: functional smad suppressing element 18 [...    63   8e-10
gi|73476377 LBXCOR1 homolog [Homo sapiens]                             59   9e-09
gi|4506967 v-ski sarcoma viral oncogene homolog [Homo sapiens]         51   3e-06
gi|148762982 hypothetical protein LOC387640 [Homo sapiens]             51   3e-06
gi|56549694 enabled homolog isoform a [Homo sapiens]                   50   4e-06
gi|39930375 enabled homolog isoform b [Homo sapiens]                   50   4e-06
gi|148746195 trichohyalin [Homo sapiens]                               48   2e-05
gi|7661936 scaffold attachment factor B2 [Homo sapiens]                47   5e-05
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     47   6e-05
gi|22035606 mitogen-activated protein kinase kinase kinase kinas...    47   6e-05
gi|22035602 mitogen-activated protein kinase kinase kinase kinas...    47   6e-05
gi|22035604 mitogen-activated protein kinase kinase kinase kinas...    47   6e-05
gi|4505101 microtubule-associated protein 7 [Homo sapiens]             47   6e-05
gi|223029422 SKI-like isoform 3 [Homo sapiens]                         45   1e-04
gi|223029420 SKI-like isoform 2 [Homo sapiens]                         45   1e-04
gi|223029418 SKI-like isoform 1 [Homo sapiens]                         45   1e-04
gi|4503509 eukaryotic translation initiation factor 3, subunit 1...    45   1e-04
gi|67763814 death-inducing-protein [Homo sapiens]                      44   4e-04
gi|62244004 modulator of estrogen induced transcription isoform ...    43   7e-04
gi|63176611 modulator of estrogen induced transcription isoform ...    43   7e-04
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]           43   7e-04
gi|31377798 rabaptin, RAB GTPase binding effector protein 1 isof...    43   7e-04

>gi|213972566 dachshund 2 isoform b [Homo sapiens]
          Length = 571

 Score = 1128 bits (2917), Expect = 0.0
 Identities = 571/571 (100%), Positives = 571/571 (100%)

Query: 1   MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR 60
           MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR
Sbjct: 1   MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR 60

Query: 61  GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP 120
           GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP
Sbjct: 61  GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP 120

Query: 121 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNASSRPGRPPKRSLGVLQEN 180
           VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNASSRPGRPPKRSLGVLQEN
Sbjct: 121 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNASSRPGRPPKRSLGVLQEN 180

Query: 181 ARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGNGSQNGTESEPDDL 240
           ARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGNGSQNGTESEPDDL
Sbjct: 181 ARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGNGSQNGTESEPDDL 240

Query: 241 NSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLNPLQQNHLLTNRLD 300
           NSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLNPLQQNHLLTNRLD
Sbjct: 241 NSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLNPLQQNHLLTNRLD 300

Query: 301 LPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLSRAGTSVIKERIPE 360
           LPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLSRAGTSVIKERIPE
Sbjct: 301 LPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLSRAGTSVIKERIPE 360

Query: 361 SPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLT 420
           SPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLT
Sbjct: 361 SPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLT 420

Query: 421 PGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYR 480
           PGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYR
Sbjct: 421 PGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYR 480

Query: 481 EREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQATTS 540
           EREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQATTS
Sbjct: 481 EREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQATTS 540

Query: 541 DSGLRMLKDTGIPDIEIENNGTPHDSAAMQA 571
           DSGLRMLKDTGIPDIEIENNGTPHDSAAMQA
Sbjct: 541 DSGLRMLKDTGIPDIEIENNGTPHDSAAMQA 571


>gi|16876441 dachshund 2 isoform a [Homo sapiens]
          Length = 599

 Score = 1117 bits (2889), Expect = 0.0
 Identities = 570/583 (97%), Positives = 570/583 (97%), Gaps = 13/583 (2%)

Query: 1   MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR 60
           MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR
Sbjct: 1   MAVSASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGR 60

Query: 61  GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP 120
           GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP
Sbjct: 61  GNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISP 120

Query: 121 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNA-------------SSRPG 167
           VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNA             SSRPG
Sbjct: 121 VVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQMTRKQAVNSSRPG 180

Query: 168 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN 227
           RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN
Sbjct: 181 RPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNTLQGN 240

Query: 228 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN 287
           GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN
Sbjct: 241 GSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLN 300

Query: 288 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS 347
           PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS
Sbjct: 301 PLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLS 360

Query: 348 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI 407
           RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI
Sbjct: 361 RAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQI 420

Query: 408 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQI 467
           PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQI
Sbjct: 421 PIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQI 480

Query: 468 QQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR 527
           QQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR
Sbjct: 481 QQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR 540

Query: 528 EQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQ 570
           EQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQ
Sbjct: 541 EQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQ 583


>gi|213972568 dachshund 2 isoform c [Homo sapiens]
          Length = 432

 Score =  800 bits (2066), Expect = 0.0
 Identities = 408/408 (100%), Positives = 408/408 (100%)

Query: 163 SSRPGRPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMN 222
           SSRPGRPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMN
Sbjct: 9   SSRPGRPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMN 68

Query: 223 TLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGG 282
           TLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGG
Sbjct: 69  TLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGG 128

Query: 283 APTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQI 342
           APTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQI
Sbjct: 129 APTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQI 188

Query: 343 HSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEE 402
           HSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEE
Sbjct: 189 HSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEE 248

Query: 403 VPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARI 462
           VPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARI
Sbjct: 249 VPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARI 308

Query: 463 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 522
           QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF
Sbjct: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 368

Query: 523 ESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQ 570
           ESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQ
Sbjct: 369 ESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQ 416


>gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]
          Length = 706

 Score =  568 bits (1465), Expect = e-162
 Identities = 326/620 (52%), Positives = 395/620 (63%), Gaps = 135/620 (21%)

Query: 4   SASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGRGNT 63
           S+S   S++SS +    G    +P+YSTP  P   TP                       
Sbjct: 148 SSSSSSSSSSSSSSSSCGPLPGKPVYSTP-SPVENTPQ---------------------- 184

Query: 64  NTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVC 123
             NEC+MVD+ G KVASF ++G ELICLPQ FDLFLKHLVGGLHTVYTKLKRL+I+PVVC
Sbjct: 185 -NNECKMVDLRGAKVASFTVEGCELICLPQAFDLFLKHLVGGLHTVYTKLKRLEITPVVC 243

Query: 124 TVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNASSRPGRPPKRSLGVLQ-ENAR 182
            VEQVRILRGLGAIQPGVNRCKLI+RKDFETL+ DCTNASSRPGRPPKR+  V   EN+ 
Sbjct: 244 NVEQVRILRGLGAIQPGVNRCKLISRKDFETLYNDCTNASSRPGRPPKRTQSVTSPENSH 303

Query: 183 LLTHAVPGLLSPGLITPTGITAAA----------MAEAMKLQKMKLMAMNTLQGNGSQNG 232
           ++ H+VPGL+SPG+I PTG+TAAA          +AEAMK++K+KL AM+    + +Q+G
Sbjct: 304 IMPHSVPGLMSPGIIPPTGLTAAAAAAAAATNAAIAEAMKVKKIKLEAMSNYHASNNQHG 363

Query: 233 TESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGGAPTLNPLQQN 292
            +SE  D+NS+ G                                               
Sbjct: 364 ADSENGDMNSSVG----------------------------------------------- 376

Query: 293 HLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLSRAGTS 352
                 L+LPFMMMPHPL+PVSLPPASV MAM+QMNHL+TIANMAAAAQ+ SP SR  TS
Sbjct: 377 ------LELPFMMMPHPLIPVSLPPASVTMAMSQMNHLSTIANMAAAAQVQSPPSRVETS 430

Query: 353 VIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQ-------------------- 392
           VIKER+P+SPSPAPSLEE  RPGS  SSH SSSVSSSP++                    
Sbjct: 431 VIKERVPDSPSPAPSLEEGRRPGSHPSSHRSSSVSSSPARTESSSDRIPVHQNGLSMNQM 490

Query: 393 ---------------------MDHHLERM----EEVPVQIPIMKSPLDKIQLTP-GQALP 426
                                M H  +RM    +E P+  P  +  LDK+ LT  GQ LP
Sbjct: 491 LMGLSPNVLPGPKEGDLAGHDMGHESKRMHIEKDETPLSTPTARDSLDKLSLTGHGQPLP 550

Query: 427 AGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRE 486
            GFP PF+F D LSS+ETLLTNIQGLLKVA+DNAR QEKQ+Q EK EL+++  RERE+RE
Sbjct: 551 PGFPSPFLFPDGLSSIETLLTNIQGLLKVAIDNARAQEKQVQLEKTELKMDFLRERELRE 610

Query: 487 NLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQATTSDSGLRM 546
            LE+QLA+E ++R  +QKRLKKEKK KRKLQEALEFE+KRREQ EQ LKQA ++DS LR+
Sbjct: 611 TLEKQLAMEQKNRAIVQKRLKKEKKAKRKLQEALEFETKRREQAEQTLKQAASTDS-LRV 669

Query: 547 LKDTGIPDIEIENNGTPHDS 566
           L D+  P+IE + +G   D+
Sbjct: 670 LNDSLTPEIEADRSGGRTDA 689


>gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]
          Length = 558

 Score =  265 bits (677), Expect = 8e-71
 Identities = 150/295 (50%), Positives = 190/295 (64%), Gaps = 48/295 (16%)

Query: 4   SASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGRGNT 63
           S+S   S++SS +    G    +P+YSTP  P   TP                       
Sbjct: 148 SSSSSSSSSSSSSSSSCGPLPGKPVYSTP-SPVENTPQ---------------------- 184

Query: 64  NTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVC 123
             NEC+MVD+ G KVASF ++G ELICLPQ FDLFLKHLVGGLHTVYTKLKRL+I+PVVC
Sbjct: 185 -NNECKMVDLRGAKVASFTVEGCELICLPQAFDLFLKHLVGGLHTVYTKLKRLEITPVVC 243

Query: 124 TVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNASSRPGRPPKRSLGVLQ-ENAR 182
            VEQVRILRGLGAIQPGVNRCKLI+RKDFETL+ DCTNASSRPGRPPKR+  V   EN+ 
Sbjct: 244 NVEQVRILRGLGAIQPGVNRCKLISRKDFETLYNDCTNASSRPGRPPKRTQSVTSPENSH 303

Query: 183 LLTHAVPGLLSPGLITPTGITA----------AAMAEAMKLQKMKLMAMNTLQGNGSQNG 232
           ++ H+VPGL+SPG+I PTG+TA          AA+AEAMK++K+KL AM+    + +Q+G
Sbjct: 304 IMPHSVPGLMSPGIIPPTGLTAAAAAAAAATNAAIAEAMKVKKIKLEAMSNYHASNNQHG 363

Query: 233 TESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALA--GQPGIGGAPT 285
            +SE  D+NS+             ++P + P  +  +   +L   GQP   G P+
Sbjct: 364 ADSENGDMNSSVD-----------ETPLSTPTARDSLDKLSLTGHGQPLPPGFPS 407



 Score =  204 bits (518), Expect = 2e-52
 Identities = 107/192 (55%), Positives = 141/192 (73%), Gaps = 2/192 (1%)

Query: 376 SQTSSHTSSSVSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLTP-GQALPAGFPGPFI 434
           + ++ H S++   + S+       ++E P+  P  +  LDK+ LT  GQ LP GFP PF+
Sbjct: 351 AMSNYHASNNQHGADSENGDMNSSVDETPLSTPTARDSLDKLSLTGHGQPLPPGFPSPFL 410

Query: 435 FADSLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAV 494
           F D LSS+ETLLTNIQGLLKVA+DNAR QEKQ+Q EK EL+++  RERE+RE LE+QLA+
Sbjct: 411 FPDGLSSIETLLTNIQGLLKVAIDNARAQEKQVQLEKTELKMDFLRERELRETLEKQLAM 470

Query: 495 ELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPD 554
           E ++R  +QKRLKKEKK KRKLQEALEFE+KRREQ EQ LKQA ++DS LR+L D+  P+
Sbjct: 471 EQKNRAIVQKRLKKEKKAKRKLQEALEFETKRREQAEQTLKQAASTDS-LRVLNDSLTPE 529

Query: 555 IEIENNGTPHDS 566
           IE + +G   D+
Sbjct: 530 IEADRSGGRTDA 541


>gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]
          Length = 504

 Score =  229 bits (584), Expect = 5e-60
 Identities = 125/217 (57%), Positives = 148/217 (68%), Gaps = 26/217 (11%)

Query: 4   SASPVISATSSGAGVPGGLFRAEPLYSTPREPPRLTPNMINSFVVNNHSNSAGGGGRGNT 63
           S+S   S++SS +    G    +P+YSTP  P   TP                       
Sbjct: 148 SSSSSSSSSSSSSSSSCGPLPGKPVYSTP-SPVENTPQ---------------------- 184

Query: 64  NTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVC 123
             NEC+MVD+ G KVASF ++G ELICLPQ FDLFLKHLVGGLHTVYTKLKRL+I+PVVC
Sbjct: 185 -NNECKMVDLRGAKVASFTVEGCELICLPQAFDLFLKHLVGGLHTVYTKLKRLEITPVVC 243

Query: 124 TVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNASSRPGRPPKRSLGVLQ-ENAR 182
            VEQVRILRGLGAIQPGVNRCKLI+RKDFETL+ DCTNASSRPGRPPKR+  V   EN+ 
Sbjct: 244 NVEQVRILRGLGAIQPGVNRCKLISRKDFETLYNDCTNASSRPGRPPKRTQSVTSPENSH 303

Query: 183 LLTHAVPGLLSPGLITPTGITAAAMAEAM-KLQKMKL 218
           ++ H+VPGL+SPG+I PT  T  +   A   L K+ L
Sbjct: 304 IMPHSVPGLMSPGIIPPTDETPLSTPTARDSLDKLSL 340



 Score =  202 bits (513), Expect = 9e-52
 Identities = 114/201 (56%), Positives = 142/201 (70%), Gaps = 8/201 (3%)

Query: 373 RPGSQTSSHTSSSVS-----SSPSQMDHHL-ERMEEVPVQIPIMKSPLDKIQLTP-GQAL 425
           RP  +T S TS   S     S P  M   +    +E P+  P  +  LDK+ LT  GQ L
Sbjct: 288 RPPKRTQSVTSPENSHIMPHSVPGLMSPGIIPPTDETPLSTPTARDSLDKLSLTGHGQPL 347

Query: 426 PAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIR 485
           P GFP PF+F D LSS+ETLLTNIQGLLKVA+DNAR QEKQ+Q EK EL+++  RERE+R
Sbjct: 348 PPGFPSPFLFPDGLSSIETLLTNIQGLLKVAIDNARAQEKQVQLEKTELKMDFLRERELR 407

Query: 486 ENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQATTSDSGLR 545
           E LE+QLA+E ++R  +QKRLKKEKK KRKLQEALEFE+KRREQ EQ LKQA ++DS LR
Sbjct: 408 ETLEKQLAMEQKNRAIVQKRLKKEKKAKRKLQEALEFETKRREQAEQTLKQAASTDS-LR 466

Query: 546 MLKDTGIPDIEIENNGTPHDS 566
           +L D+  P+IE + +G   D+
Sbjct: 467 VLNDSLTPEIEADRSGGRTDA 487


>gi|239757043 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 996

 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 37/123 (30%), Positives = 61/123 (49%), Gaps = 2/123 (1%)

Query: 59  GRGNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDI 118
           G  N   N+   V ++G+ + S ++DGQE +CL Q+ +  LK+     + ++ +   L I
Sbjct: 32  GHANLKPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTLLKNF--SYNEIHNRRVALGI 89

Query: 119 SPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNASSRPGRPPKRSLGVLQ 178
           + V CT  Q+ ILR  GA+     RC +IT+++ E L       +  P  P   +  V  
Sbjct: 90  TCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFLGENRPPKLPDNFAFDVSH 149

Query: 179 ENA 181
           E A
Sbjct: 150 ECA 152


>gi|239751555 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 37/123 (30%), Positives = 61/123 (49%), Gaps = 2/123 (1%)

Query: 59  GRGNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDI 118
           G  N   N+   V ++G+ + S ++DGQE +CL Q+ +  LK+     + ++ +   L I
Sbjct: 32  GHANLKPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTLLKNF--SYNEIHNRRVALGI 89

Query: 119 SPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNASSRPGRPPKRSLGVLQ 178
           + V CT  Q+ ILR  GA+     RC +IT+++ E L       +  P  P   +  V  
Sbjct: 90  TCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFLGENRPPKLPDNFAFDVSH 149

Query: 179 ENA 181
           E A
Sbjct: 150 ECA 152


>gi|239746067 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 37/123 (30%), Positives = 61/123 (49%), Gaps = 2/123 (1%)

Query: 59  GRGNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDI 118
           G  N   N+   V ++G+ + S ++DGQE +CL Q+ +  LK+     + ++ +   L I
Sbjct: 32  GHANLKPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTLLKNF--SYNEIHNRRVALGI 89

Query: 119 SPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNASSRPGRPPKRSLGVLQ 178
           + V CT  Q+ ILR  GA+     RC +IT+++ E L       +  P  P   +  V  
Sbjct: 90  TCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFLGENRPPKLPDNFAFDVSH 149

Query: 179 ENA 181
           E A
Sbjct: 150 ECA 152


>gi|73476377 LBXCOR1 homolog [Homo sapiens]
          Length = 921

 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 2/145 (1%)

Query: 37  RLTPNMINSFVVNNHSNSAGGGGRGNTNTNECRMVDMHGMKVASFLMDGQELICLPQVFD 96
           +L P    S   N+        G      N+     ++G+ + S ++DGQE +CL Q+ +
Sbjct: 37  QLGPGREGSSSPNSKQELQPYSGSSALKPNQVGETSLYGVPIVSLVIDGQERLCLAQISN 96

Query: 97  LFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLF 156
             LK+     + ++ +   L I+ V CT  Q+ ILR  GA+     RC +IT+++ E L 
Sbjct: 97  TLLKNY--SYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLC 154

Query: 157 TDCTNASSRPGRPPKRSLGVLQENA 181
                    P  P   +  V+ E A
Sbjct: 155 KSFLGEHKPPKLPENFAFDVVHECA 179


>gi|4506967 v-ski sarcoma viral oncogene homolog [Homo sapiens]
          Length = 728

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 64/268 (23%), Positives = 115/268 (42%), Gaps = 31/268 (11%)

Query: 333 IANMAAAAQIHSPLSRAGTSVIKERIPESPSPAPSLEENHRPGS-QTSSHTSSSVSSSPS 391
           +A  A    + SP   A  S   E +     P         PG+ +T +  ++      S
Sbjct: 421 LAPPAQQKVVSSPPCAAAVSRAPEPLATCTQPRKRKLTVDTPGAPETLAPVAAPEEDKDS 480

Query: 392 QMDHHLERMEEVPVQIPIMKSPL------DKIQLTPG-QALPAGFPGPFIFADSLSSVET 444
           + +  +E  EE    +  + SP        K   +PG +ALP+  P     AD+ S +E 
Sbjct: 481 EAEVEVESREEFTSSLSSLSSPSFTSSSSAKDLGSPGARALPSAVPDAAAPADAPSGLEA 540

Query: 445 LLTNIQGLLKVALDNARIQEK--------QIQQEKKELRLELYREREIRENLERQLAV-- 494
            L +++  L+  LD    +EK        +++QE+K L   L  +R + + LE       
Sbjct: 541 ELEHLRQALEGGLDTKEAKEKFLHEVVKMRVKQEEK-LSAALQAKRSLHQELEFLRVAKK 599

Query: 495 -ELQSRTTMQKRLKKE-----KKTKRKLQEALEFESKRREQVEQALKQATTSDSG----- 543
            +L+  T  ++ L+KE      + ++K++EA E   + + ++EQA +QA   D G     
Sbjct: 600 EKLREATEAKRNLRKEIERLRAENEKKMKEANESRLRLKRELEQA-RQARVCDKGCEAGR 658

Query: 544 LRMLKDTGIPDIEIENNGTPHDSAAMQA 571
           LR      I D++++      D   ++A
Sbjct: 659 LRAKYSAQIEDLQVKLQHAEADREQLRA 686



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 3/92 (3%)

Query: 64  NTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVC 123
           +T  C  V + G  ++ F++ G++ +CLPQ+ +  L+     L  +      L I    C
Sbjct: 97  STERCETV-LEGETISCFVVGGEKRLCLPQILNSVLRDF--SLQQINAVCDELHIYCSRC 153

Query: 124 TVEQVRILRGLGAIQPGVNRCKLITRKDFETL 155
           T +Q+ IL+ +G +      C LIT+ D E L
Sbjct: 154 TADQLEILKVMGILPFSAPSCGLITKTDAERL 185



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 14/43 (32%), Positives = 31/43 (72%), Gaps = 1/43 (2%)

Query: 457 LDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSR 499
           +++ +++ +  + ++++LR +L RERE RE+LE+ +  ELQ +
Sbjct: 667 IEDLQVKLQHAEADREQLRADLLREREAREHLEK-VVKELQEQ 708


>gi|148762982 hypothetical protein LOC387640 [Homo sapiens]
          Length = 908

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 25/88 (28%), Positives = 51/88 (57%), Gaps = 2/88 (2%)

Query: 72  DMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRIL 131
           ++ G+++   ++ G+++  L QVF   LK++     TV+ ++  L +    C +E++R L
Sbjct: 10  EVDGVRLGYLIIKGKQMFALSQVFTDLLKNIPRT--TVHKRMDHLKVKKHHCDLEELRKL 67

Query: 132 RGLGAIQPGVNRCKLITRKDFETLFTDC 159
           + + +I     +C LI+R+D E L+T C
Sbjct: 68  KAINSIAFHAAKCTLISREDVEALYTSC 95


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 35/116 (30%), Positives = 61/116 (52%), Gaps = 5/116 (4%)

Query: 457 LDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEK--KTKR 514
           L+  R++ ++++QE+ E   +   ERE +E LERQ  +E Q R   Q+RL +E+  + +R
Sbjct: 176 LERERLERERLEQEQLERERQ---ERERQERLERQERLERQERLERQERLDRERQERQER 232

Query: 515 KLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQ 570
           +  E LE E + RE+ EQ  ++    +   R+        +E   N    DS+A +
Sbjct: 233 ERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASE 288



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 31/127 (24%), Positives = 64/127 (50%), Gaps = 16/127 (12%)

Query: 457 LDNARIQEKQIQQEKKEL----------RLELYREREIRENLERQLAVELQSRTTMQKRL 506
           L+  R++++Q+++E++E           RLE     E +E L+R+   E Q R  ++ RL
Sbjct: 181 LERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRE-RQERQERERLE-RL 238

Query: 507 KKEKKTKRKLQEALE---FESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTP 563
           ++E++ +R+ QE LE    E +R  ++  A   A+       +L D+   +  ++    P
Sbjct: 239 ERERQ-ERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQP 297

Query: 564 HDSAAMQ 570
            ++ + Q
Sbjct: 298 AETPSQQ 304



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 22/78 (28%), Positives = 41/78 (52%), Gaps = 7/78 (8%)

Query: 466 QIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQK-RLKKEKKTKRKL------QE 518
           Q+Q    +  LE+ R +   +  +++L  E   R  M++ RL++E+  + +L      QE
Sbjct: 130 QVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQE 189

Query: 519 ALEFESKRREQVEQALKQ 536
            LE E + RE+ E+  +Q
Sbjct: 190 QLERERQERERQERLERQ 207


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 35/116 (30%), Positives = 61/116 (52%), Gaps = 5/116 (4%)

Query: 457 LDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEK--KTKR 514
           L+  R++ ++++QE+ E   +   ERE +E LERQ  +E Q R   Q+RL +E+  + +R
Sbjct: 176 LERERLERERLEQEQLERERQ---ERERQERLERQERLERQERLERQERLDRERQERQER 232

Query: 515 KLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQ 570
           +  E LE E + RE+ EQ  ++    +   R+        +E   N    DS+A +
Sbjct: 233 ERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASE 288



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 31/127 (24%), Positives = 64/127 (50%), Gaps = 16/127 (12%)

Query: 457 LDNARIQEKQIQQEKKEL----------RLELYREREIRENLERQLAVELQSRTTMQKRL 506
           L+  R++++Q+++E++E           RLE     E +E L+R+   E Q R  ++ RL
Sbjct: 181 LERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRE-RQERQERERLE-RL 238

Query: 507 KKEKKTKRKLQEALE---FESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTP 563
           ++E++ +R+ QE LE    E +R  ++  A   A+       +L D+   +  ++    P
Sbjct: 239 ERERQ-ERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQP 297

Query: 564 HDSAAMQ 570
            ++ + Q
Sbjct: 298 AETPSQQ 304



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 22/78 (28%), Positives = 41/78 (52%), Gaps = 7/78 (8%)

Query: 466 QIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQK-RLKKEKKTKRKL------QE 518
           Q+Q    +  LE+ R +   +  +++L  E   R  M++ RL++E+  + +L      QE
Sbjct: 130 QVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQE 189

Query: 519 ALEFESKRREQVEQALKQ 536
            LE E + RE+ E+  +Q
Sbjct: 190 QLERERQERERQERLERQ 207


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 31/87 (35%), Positives = 51/87 (58%), Gaps = 2/87 (2%)

Query: 461 RIQEKQIQQEKKELRLELYREREIRENLERQ-LAVELQSRTTMQKRLKKEKKTKRKL-QE 518
           R +E+++Q+E+ + + EL  E E    LERQ L  E Q     Q+RL++E++ +RK  +E
Sbjct: 254 RKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEE 313

Query: 519 ALEFESKRREQVEQALKQATTSDSGLR 545
             E + +RREQ E+  +Q    +  LR
Sbjct: 314 RREQQEERREQQERREQQEERREQQLR 340



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 25/86 (29%), Positives = 47/86 (54%), Gaps = 5/86 (5%)

Query: 461 RIQEKQIQQEKKELRLELYRERE-----IRENLERQLAVELQSRTTMQKRLKKEKKTKRK 515
           R +EK+++QE++E RL+  +E        RE   RQ  ++ +    +++RLK+E+  + +
Sbjct: 552 REEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLE 611

Query: 516 LQEALEFESKRREQVEQALKQATTSD 541
            +E  E   KR E  E+  +Q   S+
Sbjct: 612 QEERREQRLKREEPEEERRQQLLKSE 637



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 24/72 (33%), Positives = 43/72 (59%), Gaps = 5/72 (6%)

Query: 463 QEKQIQQEKKELRLELYREREIRENLERQLAVE-LQSRTTMQKRLKKEKKTKR----KLQ 517
           +E++ QQE++E +L   +E    + L+RQ   E LQ R   +++L++E++ +R    K +
Sbjct: 494 EERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKRE 553

Query: 518 EALEFESKRREQ 529
           E    E +RREQ
Sbjct: 554 EEKRLEQERREQ 565



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 26/73 (35%), Positives = 45/73 (61%), Gaps = 3/73 (4%)

Query: 461  RIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQE-A 519
            R +E+Q+Q E++E RL   R+R+ R   E Q A + +SR   Q+  ++E++ +R+ +E  
Sbjct: 1822 RWEEEQLQLEEQEQRLRQERDRQYR--AEEQFATQEKSRREEQELWQEEEQKRRQERERK 1879

Query: 520  LEFESKRREQVEQ 532
            L  E  RR+Q E+
Sbjct: 1880 LREEHIRRQQKEE 1892



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 24/84 (28%), Positives = 50/84 (59%), Gaps = 10/84 (11%)

Query: 463 QEKQIQQEKKELRL----ELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQE 518
           +++++Q+E+++LR     EL RER+  E  +++L  E Q R   ++  +++++ +R+ QE
Sbjct: 267 RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQE 326

Query: 519 ALEFESKRREQV------EQALKQ 536
             E + +RREQ       E+  +Q
Sbjct: 327 RREQQEERREQQLRREQEERREQQ 350



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 25/74 (33%), Positives = 48/74 (64%), Gaps = 3/74 (4%)

Query: 463  QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 522
            +E+++QQE+++L  E  RE+  R+ LERQ   E + +   +++L +E+  KR+ QE LE 
Sbjct: 1112 EEEELQQEEEQLLRE-EREKRRRQELERQYREEEEVQQE-EEQLLREEPEKRRRQE-LER 1168

Query: 523  ESKRREQVEQALKQ 536
            + +  E+++Q  +Q
Sbjct: 1169 QYREEEELQQEEEQ 1182



 Score = 37.0 bits (84), Expect = 0.049
 Identities = 23/69 (33%), Positives = 41/69 (59%), Gaps = 1/69 (1%)

Query: 461 RIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEAL 520
           R QE++ +++++E R +  R  +  E  E+QL  E + R   Q R ++E++ +R+ Q   
Sbjct: 308 RKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE-RREQQLRR 366

Query: 521 EFESKRREQ 529
           E E +RREQ
Sbjct: 367 EQEEERREQ 375



 Score = 37.0 bits (84), Expect = 0.049
 Identities = 29/90 (32%), Positives = 49/90 (54%), Gaps = 5/90 (5%)

Query: 463 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKR----LKKEKKTKRKLQE 518
           +E+Q+++E++E R E    RE +   E+QL  E Q R   Q R    L++E++ +R+ Q 
Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 419

Query: 519 ALEFESKRREQVEQALKQATTSDSGLRMLK 548
             E +  RREQ E+  +Q    +   + LK
Sbjct: 420 RRE-QQLRREQEEERHEQKHEQERREQRLK 448



 Score = 37.0 bits (84), Expect = 0.049
 Identities = 23/82 (28%), Positives = 46/82 (56%), Gaps = 1/82 (1%)

Query: 454 KVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTK 513
           K AL     +E+Q+ QE++E      RE+  R+  ERQ   E Q +   ++ L++E++ +
Sbjct: 892 KPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKR 951

Query: 514 RKLQEALEF-ESKRREQVEQAL 534
           R+ +   ++ + K+ +Q E+ L
Sbjct: 952 RRQERERQYRKDKKLQQKEEQL 973



 Score = 36.6 bits (83), Expect = 0.064
 Identities = 22/67 (32%), Positives = 40/67 (59%), Gaps = 1/67 (1%)

Query: 463 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 522
           +E+Q ++E++E R E    RE  E  E+QL  E Q     +++L++E++ +R+ Q+    
Sbjct: 322 REQQERREQQEERREQQLRREQEERREQQLRRE-QEEERREQQLRREQEEERREQQLRRE 380

Query: 523 ESKRREQ 529
           +  RREQ
Sbjct: 381 QQLRREQ 387



 Score = 36.6 bits (83), Expect = 0.064
 Identities = 26/76 (34%), Positives = 48/76 (63%), Gaps = 7/76 (9%)

Query: 463  QEKQIQQEKKELRLELYREREIRENLERQLAV--ELQSRTTMQKRLKKEKKTKRKLQEAL 520
            +E+++QQE+++L  E  RE+  R+  ERQ     ELQ     +++L +E++ KR+LQE  
Sbjct: 992  EEEELQQEEEQLLRE-EREKRRRQEWERQYRKKDELQQE---EEQLLREEREKRRLQER- 1046

Query: 521  EFESKRREQVEQALKQ 536
            E + +  E+++Q  +Q
Sbjct: 1047 ERQYREEEELQQEEEQ 1062



 Score = 36.2 bits (82), Expect = 0.083
 Identities = 23/84 (27%), Positives = 49/84 (58%), Gaps = 3/84 (3%)

Query: 463 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 522
           ++++ ++ ++ L+LE    RE +E  E+QL  E + R   ++RLK++++ +R LQ+ L  
Sbjct: 478 RDQEEERRERWLKLEEEERREQQERREQQLRREQEERR--EQRLKRQEEEER-LQQRLRS 534

Query: 523 ESKRREQVEQALKQATTSDSGLRM 546
           E + R + E+  +Q    +   R+
Sbjct: 535 EQQLRREQEERREQLLKREEEKRL 558



 Score = 36.2 bits (82), Expect = 0.083
 Identities = 23/76 (30%), Positives = 43/76 (56%), Gaps = 2/76 (2%)

Query: 463  QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 522
            +E+Q+ +E+ E R    RER+ RE  E Q   E   R   +KR ++E + + + +E ++ 
Sbjct: 1089 EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148

Query: 523  ESKR--REQVEQALKQ 536
            E ++  RE+ E+  +Q
Sbjct: 1149 EEEQLLREEPEKRRRQ 1164



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 22/76 (28%), Positives = 45/76 (59%), Gaps = 2/76 (2%)

Query: 463  QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 522
            +E+Q+ +E++E R    RER+ R++ + Q   E       +KR ++E++ K + +E L+ 
Sbjct: 939  EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQ 998

Query: 523  ESKR--REQVEQALKQ 536
            E ++  RE+ E+  +Q
Sbjct: 999  EEEQLLREEREKRRRQ 1014



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 24/88 (27%), Positives = 50/88 (56%), Gaps = 2/88 (2%)

Query: 463 QEKQIQQEKKELR-LELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRK-LQEAL 520
           +E+Q+++E++  R  +L RE+++R   E +   +   +   ++RLK+E++ +R  L+   
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREE 462

Query: 521 EFESKRREQVEQALKQATTSDSGLRMLK 548
           E E   +E+ +Q LK+    +   R LK
Sbjct: 463 ETERHEQERRKQQLKRDQEEERRERWLK 490



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 23/74 (31%), Positives = 46/74 (62%), Gaps = 3/74 (4%)

Query: 463 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 522
           +E+Q+++E+ +LR E    RE +   E+QL  E Q R   +++L++E++ +R+ +E    
Sbjct: 379 REQQLRREQ-QLRREQQLRREQQLRREQQLRREQQLR--REQQLRREQQLRREQEEERHE 435

Query: 523 ESKRREQVEQALKQ 536
           +   +E+ EQ LK+
Sbjct: 436 QKHEQERREQRLKR 449



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 22/77 (28%), Positives = 48/77 (62%), Gaps = 5/77 (6%)

Query: 461  RIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSR-TTMQKRLKKEKKTKRKLQEA 519
            R +E+Q++++++E +     ++  R+ LER+   E Q R  T Q++L+++++ ++ L+E 
Sbjct: 1694 REEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEE- 1752

Query: 520  LEFESKRREQVEQALKQ 536
               E  R E+ EQ L++
Sbjct: 1753 ---EQLRPEREEQQLRR 1766



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 21/83 (25%), Positives = 46/83 (55%), Gaps = 8/83 (9%)

Query: 458  DNARIQEKQIQQEKKELRLELYREREIRENLERQLAV--------ELQSRTTMQKRLKKE 509
            D  + +E+Q+ +E++E R    RER+ RE  E Q           E + R  ++++ +KE
Sbjct: 1024 DELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKE 1083

Query: 510  KKTKRKLQEALEFESKRREQVEQ 532
            ++ +++ ++ L  E ++R + E+
Sbjct: 1084 EELQQEEEQLLREEPEKRRRQER 1106



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 20/74 (27%), Positives = 47/74 (63%), Gaps = 3/74 (4%)

Query: 463  QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 522
            ++ ++QQE+++L  E   +R ++E  ERQ   E + +   ++ L +E++T+R+  + LE 
Sbjct: 1022 KKDELQQEEEQLLREEREKRRLQER-ERQYREEEELQQEEEQLLGEERETRRR--QELER 1078

Query: 523  ESKRREQVEQALKQ 536
            + ++ E+++Q  +Q
Sbjct: 1079 QYRKEEELQQEEEQ 1092



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 22/76 (28%), Positives = 43/76 (56%), Gaps = 2/76 (2%)

Query: 463  QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 522
            +E+Q+  E++E R     ER+ R+  E Q   E   R   +KR ++E++ + + +E L+ 
Sbjct: 1059 EEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQ 1118

Query: 523  ESKR--REQVEQALKQ 536
            E ++  RE+ E+  +Q
Sbjct: 1119 EEEQLLREEREKRRRQ 1134



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 21/70 (30%), Positives = 39/70 (55%)

Query: 463  QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 522
            +E+Q+ +E++E R     ER+ RE  E Q   E   R   +KR ++E + + + +E L+ 
Sbjct: 1119 EEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178

Query: 523  ESKRREQVEQ 532
            E ++  + EQ
Sbjct: 1179 EEEQLLREEQ 1188



 Score = 33.5 bits (75), Expect = 0.54
 Identities = 23/86 (26%), Positives = 47/86 (54%), Gaps = 12/86 (13%)

Query: 463 QEKQIQQEKKELRLELYREREIREN------------LERQLAVELQSRTTMQKRLKKEK 510
           +E+Q+++E++E R E   E+E RE             L+R+   E   +   +++LK+++
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480

Query: 511 KTKRKLQEALEFESKRREQVEQALKQ 536
           + +R+ +     E +RREQ E+  +Q
Sbjct: 481 EEERRERWLKLEEEERREQQERREQQ 506



 Score = 33.5 bits (75), Expect = 0.54
 Identities = 24/78 (30%), Positives = 43/78 (55%), Gaps = 4/78 (5%)

Query: 463 QEKQIQQEKKELRLELYREREIRENLER---QLAVELQSRTTMQ-KRLKKEKKTKRKLQE 518
           Q K+ Q+E++  R     E E RE  ER   QL  E + R   + KR ++E++ +++L+ 
Sbjct: 475 QLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRS 534

Query: 519 ALEFESKRREQVEQALKQ 536
             +   ++ E+ EQ LK+
Sbjct: 535 EQQLRREQEERREQLLKR 552



 Score = 33.5 bits (75), Expect = 0.54
 Identities = 20/76 (26%), Positives = 46/76 (60%), Gaps = 3/76 (3%)

Query: 463  QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 522
            +E+Q+QQE+++L  E  RE+  R+  ERQ   + + +   ++ L +E + +R+ +   ++
Sbjct: 932  EEEQLQQEEEQLLRE-EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKY 990

Query: 523  --ESKRREQVEQALKQ 536
              E + +++ EQ L++
Sbjct: 991  REEEELQQEEEQLLRE 1006



 Score = 33.5 bits (75), Expect = 0.54
 Identities = 24/75 (32%), Positives = 45/75 (60%), Gaps = 5/75 (6%)

Query: 463  QEKQIQQEKKELRLELYREREIRENLERQLAV-ELQSRTTMQKRLKKEKKTKRKLQEALE 521
            +E+++QQE+++L   L  E E R   ER+    E +     +++L +E++ KR+ QE LE
Sbjct: 1082 KEEELQQEEEQL---LREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE-LE 1137

Query: 522  FESKRREQVEQALKQ 536
             + +  E+V+Q  +Q
Sbjct: 1138 RQYREEEEVQQEEEQ 1152



 Score = 33.1 bits (74), Expect = 0.71
 Identities = 24/74 (32%), Positives = 43/74 (58%), Gaps = 4/74 (5%)

Query: 463 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 522
           +E+Q Q+ ++E +L   +E E RE  E +   E Q R   Q+  ++E++ +R+ +E  E 
Sbjct: 293 EEQQQQRLRREQQLRRKQEEERREQQEERR--EQQERREQQEE-RREQQLRREQEERRE- 348

Query: 523 ESKRREQVEQALKQ 536
           +  RREQ E+  +Q
Sbjct: 349 QQLRREQEEERREQ 362



 Score = 33.1 bits (74), Expect = 0.71
 Identities = 27/85 (31%), Positives = 50/85 (58%), Gaps = 15/85 (17%)

Query: 463 QEKQIQQEKKELRLELYREREIR-----ENLERQLAVELQSRTTMQKR----LKKEKKTK 513
           +E+Q+++E++E R    RE+++R     E  E+QL  E Q R   Q R    L++E++ +
Sbjct: 347 REQQLRREQEEER----REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402

Query: 514 RKLQEALEFESKRREQV--EQALKQ 536
           R+ Q   E + +R +Q+  EQ L++
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRR 427



 Score = 32.7 bits (73), Expect = 0.92
 Identities = 22/84 (26%), Positives = 45/84 (53%), Gaps = 10/84 (11%)

Query: 463  QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEAL-- 520
            +E+Q+ +E++E R     ER+ R+  E Q   E   R   +KR  +E++ + + +E L  
Sbjct: 999  EEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQ 1058

Query: 521  --------EFESKRREQVEQALKQ 536
                    E E++RR+++E+  ++
Sbjct: 1059 EEEQLLGEERETRRRQELERQYRK 1082



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 21/85 (24%), Positives = 44/85 (51%), Gaps = 15/85 (17%)

Query: 463 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRL---------------K 507
           +E+Q+++E++E R +  + +E  E L+++L  E Q R   ++R                +
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562

Query: 508 KEKKTKRKLQEALEFESKRREQVEQ 532
           +E++ KR+ +E  +   KR E+  Q
Sbjct: 563 REQRLKREQEERRDQLLKREEERRQ 587



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 25/84 (29%), Positives = 46/84 (54%), Gaps = 11/84 (13%)

Query: 463 QEKQIQQEKK---ELRLELYREREIREN-------LERQLAVELQSRTTMQKRLKKEKKT 512
           QE++  QE++   + R +L  ER+ R +       L+ QL  E Q     ++ L++E++ 
Sbjct: 860 QERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREERE 919

Query: 513 KRKLQEALEFESKRREQVEQALKQ 536
           KR+ QE  E + +  EQ++Q  +Q
Sbjct: 920 KRRRQEQ-ERQYREEEQLQQEEEQ 942



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 21/76 (27%), Positives = 44/76 (57%), Gaps = 9/76 (11%)

Query: 463 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 522
           +E+Q+++E++E R +  R  +  E  E+QL  E       Q+  ++E++ +R+ Q   E 
Sbjct: 335 REQQLRREQEERREQQLRREQEEERREQQLRRE-------QEEERREQQLRREQQLRREQ 387

Query: 523 ESKRREQV--EQALKQ 536
           + +R +Q+  EQ L++
Sbjct: 388 QLRREQQLRREQQLRR 403



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 20/69 (28%), Positives = 36/69 (52%)

Query: 463  QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 522
            +E+Q+ +E+ E R     ER+ RE  E Q   E   R   +KR ++ ++  R+ +E    
Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208

Query: 523  ESKRREQVE 531
            + K+R + E
Sbjct: 1209 KRKQRYRDE 1217



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 22/71 (30%), Positives = 43/71 (60%), Gaps = 2/71 (2%)

Query: 463 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQ-KRLKKEKKTKRKLQEALE 521
           +E+Q+++E+ +LR E    RE +   E+QL  E Q R   Q +R ++E++ ++K ++   
Sbjct: 385 REQQLRREQ-QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR 443

Query: 522 FESKRREQVEQ 532
            +  +REQ E+
Sbjct: 444 EQRLKREQEER 454



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 27/97 (27%), Positives = 51/97 (52%), Gaps = 14/97 (14%)

Query: 463 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKR---LKKEKKTKRKLQEA 519
           +E+++++E++E R  L RE E   + + +   +L+     ++R   LK E++ +R+ QE 
Sbjct: 443 REQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQER 502

Query: 520 LEFE-----SKRREQ------VEQALKQATTSDSGLR 545
            E +      +RREQ       E+ L+Q   S+  LR
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 22/73 (30%), Positives = 42/73 (57%), Gaps = 7/73 (9%)

Query: 463 QEKQIQQEKKELRLELYREREIRENLERQ------LAVELQSRTTMQKRLKKEKKTKRKL 516
           +++++++E++E RLE   +RE  E LE++      L  E       Q+ LK E++ +R+ 
Sbjct: 586 RQQRLKREQEE-RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644

Query: 517 QEALEFESKRREQ 529
           Q+    + +RREQ
Sbjct: 645 QQLRREQQERREQ 657



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 9/83 (10%)

Query: 458 DNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEK------- 510
           +  R Q  + ++ ++E R +L +  E  E  ++QL  E Q R   ++RLK+E+       
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR--EQRLKREEEEERLEQ 670

Query: 511 KTKRKLQEALEFESKRREQVEQA 533
           + KR+ +E    +    E+ EQA
Sbjct: 671 RLKREHEEERREQELAEEEQEQA 693



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 22/87 (25%), Positives = 47/87 (54%), Gaps = 10/87 (11%)

Query: 463  QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 522
            +E+Q+  E+ E R    RE++ RE  E Q           +++L +E++ KR+ QE  E 
Sbjct: 969  KEEQLLGEEPEKRRRQEREKKYREEEELQ---------QEEEQLLREEREKRRRQE-WER 1018

Query: 523  ESKRREQVEQALKQATTSDSGLRMLKD 549
            + +++++++Q  +Q    +   R L++
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQE 1045



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 22/82 (26%), Positives = 45/82 (54%), Gaps = 7/82 (8%)

Query: 462  IQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKR----LKKEKKTK---R 514
            +QE++ Q  +++ R   +RE E+R   + +  +E + R   Q+R    LK+E++ +   R
Sbjct: 1345 LQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQER 1404

Query: 515  KLQEALEFESKRREQVEQALKQ 536
            + Q   + + K RE+ +Q  +Q
Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQ 1426



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 21/79 (26%), Positives = 46/79 (58%), Gaps = 6/79 (7%)

Query: 463  QEKQIQQEKKELRLELY-REREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALE 521
            +E+Q+ QE++E +L    R+R+  E  E+QL  + + R   ++ L+ ++  ++ L+E  +
Sbjct: 1465 EEEQLLQEREEQQLHRQERDRKFLEE-EQQLRRQERDRKFREQELRSQEPERKFLEEEQQ 1523

Query: 522  FESKRRE----QVEQALKQ 536
               ++R+    Q EQ L++
Sbjct: 1524 LHRQQRQRKFLQEEQQLRR 1542



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 22/91 (24%), Positives = 52/91 (57%), Gaps = 12/91 (13%)

Query: 463  QEKQIQQEKKELRLELYREREIRENL-------ERQLAVELQSRTTMQK--RLKKEKKTK 513
            +E Q++++++E +L   R+R+ RE         E+QL  + + R   ++  +L+++++ +
Sbjct: 1648 EEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER 1707

Query: 514  RKLQEALEF---ESKRREQVEQALKQATTSD 541
            + LQE  +    E +R+ + E+ L+Q T  +
Sbjct: 1708 KFLQEEQQLRRQELERKFREEEQLRQETEQE 1738



 Score = 30.0 bits (66), Expect = 6.0
 Identities = 23/78 (29%), Positives = 41/78 (52%), Gaps = 4/78 (5%)

Query: 461  RIQEKQIQQEKKELRLELYREREIRENLERQL--AVELQSRTTMQKRLKKEKKTKRKLQE 518
            R +E+  Q+E++ L  E  RE   R+ LERQ     ELQ       R + EK+ +++ + 
Sbjct: 1051 REEEELQQEEEQLLGEE--RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERER 1108

Query: 519  ALEFESKRREQVEQALKQ 536
                E + +++ EQ L++
Sbjct: 1109 QCREEEELQQEEEQLLRE 1126



 Score = 29.6 bits (65), Expect = 7.8
 Identities = 16/69 (23%), Positives = 37/69 (53%)

Query: 461 RIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEAL 520
           R+ +++ ++E ++    L +E E  +  E Q   ELQ      ++L++++  + + +E  
Sbjct: 236 RVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQ 295

Query: 521 EFESKRREQ 529
           + +  RREQ
Sbjct: 296 QQQRLRREQ 304



 Score = 29.6 bits (65), Expect = 7.8
 Identities = 24/95 (25%), Positives = 52/95 (54%), Gaps = 2/95 (2%)

Query: 443  ETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTM 502
            E L    + LL+   +  R QE + +Q ++E  ++   E+ +RE  E++   EL+ +   
Sbjct: 1114 EELQQEEEQLLREEREKRRRQELE-RQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE 1172

Query: 503  QKRL-KKEKKTKRKLQEALEFESKRREQVEQALKQ 536
            ++ L ++E++  R+ QE    E +R+ + E+ L++
Sbjct: 1173 EEELQQEEEQLLREEQEKRRQERERQYREEEELQR 1207



 Score = 29.6 bits (65), Expect = 7.8
 Identities = 15/72 (20%), Positives = 45/72 (62%), Gaps = 3/72 (4%)

Query: 463  QEKQIQQEKKELRLELYREREIRENLERQLAVELQSR--TTMQKRLKKEKKTKRKLQEAL 520
            +E+Q++ +++E +L   R+R+ RE  E+QL+ + + R     +++++++++ ++ L+E  
Sbjct: 1395 EEQQLRCQEREQQLRQDRDRKFREE-EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQ 1453

Query: 521  EFESKRREQVEQ 532
            +   +R  +  +
Sbjct: 1454 QLRQERHRKFRE 1465



 Score = 29.6 bits (65), Expect = 7.8
 Identities = 24/82 (29%), Positives = 48/82 (58%), Gaps = 10/82 (12%)

Query: 463  QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRT-TMQKRLKK----EKKTKRKLQ 517
            +E+Q++++++  +    R+R+ RE  E QL  E + +  + Q+R +K    E+K +R+ Q
Sbjct: 1536 EEQQLRRQERGQQRRQDRDRKFRE--EEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593

Query: 518  EALEFESK---RREQVEQALKQ 536
            E    E +   RR++ +Q L+Q
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQ 1615


>gi|7661936 scaffold attachment factor B2 [Homo sapiens]
          Length = 953

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 27/70 (38%), Positives = 43/70 (61%), Gaps = 2/70 (2%)

Query: 458 DNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQ 517
           + AR+Q +++Q E +  RLE  RER  RE LER+     + R   Q+R+ +E++  R+ Q
Sbjct: 659 EKARLQRERLQLECQRQRLE--RERMERERLERERMRVERERRKEQERIHREREELRRQQ 716

Query: 518 EALEFESKRR 527
           E L +E +RR
Sbjct: 717 EQLRYEQERR 726



 Score = 36.2 bits (82), Expect = 0.083
 Identities = 21/72 (29%), Positives = 46/72 (63%), Gaps = 7/72 (9%)

Query: 463 QEKQIQQEKKELRLELYREREIRENLERQ-LAVELQSRTTMQKRLKKEKKTKRKLQ-EAL 520
           + ++ +Q ++E RLE + ER+ +  L+R+ L +E Q     ++RL++E+  + +L+ E +
Sbjct: 638 RRREREQREREQRLEAFHERKEKARLQRERLQLECQ-----RQRLERERMERERLERERM 692

Query: 521 EFESKRREQVEQ 532
             E +RR++ E+
Sbjct: 693 RVERERRKEQER 704



 Score = 32.7 bits (73), Expect = 0.92
 Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 3/72 (4%)

Query: 461 RIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEAL 520
           R +E+Q Q+E++    E  RERE RE   R+  +E       + RL++E+      ++ L
Sbjct: 621 RERERQRQREREIRETERRREREQRE---REQRLEAFHERKEKARLQRERLQLECQRQRL 677

Query: 521 EFESKRREQVEQ 532
           E E   RE++E+
Sbjct: 678 ERERMERERLER 689


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 38/130 (29%), Positives = 66/130 (50%), Gaps = 16/130 (12%)

Query: 440  SSVETLLTNIQGLL------KVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLA 493
            S++E+ L + Q LL      K++L     + KQ++ EK   R +L  E E + NLE+Q+A
Sbjct: 1304 SALESQLQDTQELLQEENRQKLSLST---KLKQVEDEKNSFREQLEEEEEAKHNLEKQIA 1360

Query: 494  VELQSRTTMQKR-------LKKEKKTKRKLQEALEFESKRREQVEQALKQATTSDSGLRM 546
                    M+K+       L+  ++ KRKLQ+ LE  S+R E+   A  +   + + L+ 
Sbjct: 1361 TLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQ 1420

Query: 547  LKDTGIPDIE 556
              D  + D++
Sbjct: 1421 ELDDLLVDLD 1430



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 30/118 (25%), Positives = 61/118 (51%), Gaps = 8/118 (6%)

Query: 439 LSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYRER----EIRENLERQLAV 494
           L+ +ETL + +    K+ L      E ++  E +ELR  L  ++    EI  +LE ++  
Sbjct: 868 LTEMETLQSQLMAE-KLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEE 926

Query: 495 ELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGI 552
           E +    +Q   KK ++  ++L+E LE E   R++++    +  T+++ L+ L++  I
Sbjct: 927 EEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQ---LEKVTTEAKLKKLEEEQI 981



 Score = 30.4 bits (67), Expect = 4.6
 Identities = 24/113 (21%), Positives = 56/113 (49%), Gaps = 2/113 (1%)

Query: 438  SLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQ 497
            S++++E  +  ++  L       +   KQ+++ +K+L+  L +  + R N E Q   +  
Sbjct: 1808 SITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAE-QYKDQAD 1866

Query: 498  SRTTMQKRLKKE-KKTKRKLQEALEFESKRREQVEQALKQATTSDSGLRMLKD 549
              +T  K+LK++ ++ + + Q A     K + ++E A + A   +  +  LK+
Sbjct: 1867 KASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKN 1919



 Score = 30.0 bits (66), Expect = 6.0
 Identities = 33/140 (23%), Positives = 61/140 (43%), Gaps = 27/140 (19%)

Query: 437  DSLSSVET-------LLTNIQGLLK------VALDNARIQEKQIQQEKKELRLELYRERE 483
            DS+  +ET       L  +++GL +       A D     + ++QQE  +L ++L  +R+
Sbjct: 1375 DSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQ 1434

Query: 484  IRENLERQ-------------LAVELQSRTTMQKRLKKEKKTKR-KLQEALEFESKRREQ 529
               NLE++             ++ +        +   +EK+TK   L  ALE   +++ +
Sbjct: 1435 SACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAE 1494

Query: 530  VEQALKQATTSDSGLRMLKD 549
            +E+  KQ  T    L   KD
Sbjct: 1495 LERLNKQFRTEMEDLMSSKD 1514


>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 3 [Homo sapiens]
          Length = 1212

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 29/93 (31%), Positives = 53/93 (56%), Gaps = 6/93 (6%)

Query: 446 LTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLE--RQLAVELQSRTTMQ 503
           + N+ G   +  D  R+Q++  ++ +   R +L +E+++RE  E  RQL  E Q R   Q
Sbjct: 343 IVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQ 402

Query: 504 K----RLKKEKKTKRKLQEALEFESKRREQVEQ 532
           K    RL+++++ +R+ +   E E +RREQ E+
Sbjct: 403 KEQRRRLEEQQRREREARRQQEREQRRREQEEK 435



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 22/91 (24%), Positives = 50/91 (54%), Gaps = 1/91 (1%)

Query: 445 LLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQK 504
           LL   Q  ++   +  R  E+Q Q+ ++E R +  RE+  RE  E++   EL+ R   ++
Sbjct: 391 LLAERQKRIEQQKEQRRRLEEQ-QRREREARRQQEREQRRREQEEKRRLEELERRRKEEE 449

Query: 505 RLKKEKKTKRKLQEALEFESKRREQVEQALK 535
             ++ ++ KR+++   E+  ++ E+ ++ L+
Sbjct: 450 ERRRAEEEKRRVEREQEYIRRQLEEEQRHLE 480


>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 1 [Homo sapiens]
          Length = 1166

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 29/93 (31%), Positives = 53/93 (56%), Gaps = 6/93 (6%)

Query: 446 LTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLE--RQLAVELQSRTTMQ 503
           + N+ G   +  D  R+Q++  ++ +   R +L +E+++RE  E  RQL  E Q R   Q
Sbjct: 343 IVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQ 402

Query: 504 K----RLKKEKKTKRKLQEALEFESKRREQVEQ 532
           K    RL+++++ +R+ +   E E +RREQ E+
Sbjct: 403 KEQRRRLEEQQRREREARRQQEREQRRREQEEK 435



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 22/91 (24%), Positives = 50/91 (54%), Gaps = 1/91 (1%)

Query: 445 LLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQK 504
           LL   Q  ++   +  R  E+Q Q+ ++E R +  RE+  RE  E++   EL+ R   ++
Sbjct: 391 LLAERQKRIEQQKEQRRRLEEQ-QRREREARRQQEREQRRREQEEKRRLEELERRRKEEE 449

Query: 505 RLKKEKKTKRKLQEALEFESKRREQVEQALK 535
             ++ ++ KR+++   E+  ++ E+ ++ L+
Sbjct: 450 ERRRAEEEKRRVEREQEYIRRQLEEEQRHLE 480


>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 2 [Homo sapiens]
          Length = 1320

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 29/93 (31%), Positives = 53/93 (56%), Gaps = 6/93 (6%)

Query: 446 LTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLE--RQLAVELQSRTTMQ 503
           + N+ G   +  D  R+Q++  ++ +   R +L +E+++RE  E  RQL  E Q R   Q
Sbjct: 343 IVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQ 402

Query: 504 K----RLKKEKKTKRKLQEALEFESKRREQVEQ 532
           K    RL+++++ +R+ +   E E +RREQ E+
Sbjct: 403 KEQRRRLEEQQRREREARRQQEREQRRREQEEK 435



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 22/91 (24%), Positives = 50/91 (54%), Gaps = 1/91 (1%)

Query: 445 LLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQK 504
           LL   Q  ++   +  R  E+Q Q+ ++E R +  RE+  RE  E++   EL+ R   ++
Sbjct: 391 LLAERQKRIEQQKEQRRRLEEQ-QRREREARRQQEREQRRREQEEKRRLEELERRRKEEE 449

Query: 505 RLKKEKKTKRKLQEALEFESKRREQVEQALK 535
             ++ ++ KR+++   E+  ++ E+ ++ L+
Sbjct: 450 ERRRAEEEKRRVEREQEYIRRQLEEEQRHLE 480


>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
          Length = 749

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 62/258 (24%), Positives = 108/258 (41%), Gaps = 35/258 (13%)

Query: 297 NRLDLPFMMMPH----PLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLSRAGTS 352
           +RL LP   +PH    P    SLPP SV                AA AQ+  P S     
Sbjct: 327 SRLWLPSKSLPHLPGTPRPTSSLPPGSVK---------------AAPAQVRPP-SPGNIR 370

Query: 353 VIKERIPESPSPAPSLEENHRPGSQTS-SHTSSSVSSSPSQMDHHLERMEEVPVQIPIMK 411
            +K  +   P      +E  +  ++ S    +  V    + ++       EV    P M 
Sbjct: 371 PVKREVKVEPEKKDPEKEPQKVANEPSLKGRAPLVKVEEATVEERTPAEPEVGPAAPAM- 429

Query: 412 SPLDKIQLTPGQA-LPAGFPGPFIFADSLSSVETLL--------TNIQGLLKVALDNARI 462
           +P       P  A  PA  P P + +   S+V            T+ +   ++  +  R+
Sbjct: 430 APAPASAPAPASAPAPAPVPTPAMVSAPSSTVNASASVKTSAGTTDPEEATRLLAEKRRL 489

Query: 463 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQ-KRLKKEKKTKRKLQ---E 518
             +Q ++E++E R +   ER+ RE L +++A E  +R   + +RL+ E+  +++ Q   +
Sbjct: 490 AREQREKEERERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQAREKEEQLQRQ 549

Query: 519 ALEFESKRREQVEQALKQ 536
           A E   + RE+ E+A +Q
Sbjct: 550 AEERALREREEAERAQRQ 567



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 30/103 (29%), Positives = 58/103 (56%), Gaps = 8/103 (7%)

Query: 454 KVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQK-RLKKEKKT 512
           ++  + AR +E+Q+Q++ +E  L   RERE  E  +RQ   E + R   ++ R ++EK  
Sbjct: 533 RLEAEQAREKEEQLQRQAEERAL---REREEAERAQRQKEEEARVREEAERVRQEREKHF 589

Query: 513 KRKLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDI 555
           +R+ QE LE    R++++E+ +K+   +++  +   D    DI
Sbjct: 590 QREEQERLE----RKKRLEEIMKRTRRTEATDKKTSDQRNGDI 628



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 11/68 (16%)

Query: 482 REIRENLERQLAV--------ELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQA 533
           RE RE  E+QLA         E ++R   +K L++ KK   +L+E  + E +RR  VE+ 
Sbjct: 71  RERREEREKQLAAREIVWLEREERARQHYEKHLEERKK---RLEEQRQKEERRRAAVEEK 127

Query: 534 LKQATTSD 541
            +Q    D
Sbjct: 128 RRQRLEED 135


>gi|223029422 SKI-like isoform 3 [Homo sapiens]
          Length = 664

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 37/124 (29%), Positives = 55/124 (44%), Gaps = 14/124 (11%)

Query: 64  NTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVC 123
           ++ E     + G  ++ F + G++ +CLPQV +  L+     L  + T    L I    C
Sbjct: 120 SSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFT--LQQINTVCDELYIYCSRC 177

Query: 124 TVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNASSRPGR--------PPKRSLG 175
           T +Q+ IL+ LG +      C LIT  D + L     NA  RP          P K SL 
Sbjct: 178 TSDQLHILKVLGILPFNAPSCGLITLTDAQRL----CNALLRPRTFPQNGSVLPAKSSLA 233

Query: 176 VLQE 179
            L+E
Sbjct: 234 QLKE 237



 Score = 33.5 bits (75), Expect = 0.54
 Identities = 43/201 (21%), Positives = 84/201 (41%), Gaps = 43/201 (21%)

Query: 364 PAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQ 423
           P  SLEE  +   +TS    S + +S S       + E     +      ++K+    G 
Sbjct: 434 PDVSLEEQEKMDLKTSRELCSRLDASISNNSTSKRKSESATCNLV---RDINKV----GI 486

Query: 424 ALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQIQ---QEKKELRLELYR 480
            L A    P +  D +                  D  +I E+ ++   +++++L L L +
Sbjct: 487 GLVAAASSPLLVKDVICED---------------DKGKIMEEVMRTYLKQQEKLNLILQK 531

Query: 481 EREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR------------E 528
           ++++      Q+ V++ S +   K L +E++  +K  E+L+ E  +R            +
Sbjct: 532 KQQL------QMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEK 585

Query: 529 QVEQALKQATTSDSGLRMLKD 549
           ++EQ +KQ  T DS L   K+
Sbjct: 586 KLEQIMKQKCTCDSNLEKDKE 606


>gi|223029420 SKI-like isoform 2 [Homo sapiens]
          Length = 638

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 37/124 (29%), Positives = 55/124 (44%), Gaps = 14/124 (11%)

Query: 64  NTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVC 123
           ++ E     + G  ++ F + G++ +CLPQV +  L+     L  + T    L I    C
Sbjct: 140 SSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFT--LQQINTVCDELYIYCSRC 197

Query: 124 TVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNASSRPGR--------PPKRSLG 175
           T +Q+ IL+ LG +      C LIT  D + L     NA  RP          P K SL 
Sbjct: 198 TSDQLHILKVLGILPFNAPSCGLITLTDAQRL----CNALLRPRTFPQNGSVLPAKSSLA 253

Query: 176 VLQE 179
            L+E
Sbjct: 254 QLKE 257



 Score = 33.1 bits (74), Expect = 0.71
 Identities = 26/107 (24%), Positives = 56/107 (52%), Gaps = 21/107 (19%)

Query: 458 DNARIQEKQIQ---QEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKR 514
           D  +I E+ ++   +++++L L L +++++      Q+ V++ S +   K L +E++  +
Sbjct: 480 DKGKIMEEVMRTYLKQQEKLNLILQKKQQL------QMEVKMLSSSKSMKELTEEQQNLQ 533

Query: 515 KLQEALEFESKRR------------EQVEQALKQATTSDSGLRMLKD 549
           K  E+L+ E  +R            +++EQ +KQ  T DS L   K+
Sbjct: 534 KELESLQNEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKE 580


>gi|223029418 SKI-like isoform 1 [Homo sapiens]
          Length = 684

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 37/124 (29%), Positives = 55/124 (44%), Gaps = 14/124 (11%)

Query: 64  NTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVC 123
           ++ E     + G  ++ F + G++ +CLPQV +  L+     L  + T    L I    C
Sbjct: 140 SSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFT--LQQINTVCDELYIYCSRC 197

Query: 124 TVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNASSRPGR--------PPKRSLG 175
           T +Q+ IL+ LG +      C LIT  D + L     NA  RP          P K SL 
Sbjct: 198 TSDQLHILKVLGILPFNAPSCGLITLTDAQRL----CNALLRPRTFPQNGSVLPAKSSLA 253

Query: 176 VLQE 179
            L+E
Sbjct: 254 QLKE 257



 Score = 33.5 bits (75), Expect = 0.54
 Identities = 43/201 (21%), Positives = 84/201 (41%), Gaps = 43/201 (21%)

Query: 364 PAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQ 423
           P  SLEE  +   +TS    S + +S S       + E     +      ++K+    G 
Sbjct: 454 PDVSLEEQEKMDLKTSRELCSRLDASISNNSTSKRKSESATCNLV---RDINKV----GI 506

Query: 424 ALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQIQ---QEKKELRLELYR 480
            L A    P +  D +                  D  +I E+ ++   +++++L L L +
Sbjct: 507 GLVAAASSPLLVKDVICED---------------DKGKIMEEVMRTYLKQQEKLNLILQK 551

Query: 481 EREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRR------------E 528
           ++++      Q+ V++ S +   K L +E++  +K  E+L+ E  +R            +
Sbjct: 552 KQQL------QMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEK 605

Query: 529 QVEQALKQATTSDSGLRMLKD 549
           ++EQ +KQ  T DS L   K+
Sbjct: 606 KLEQIMKQKCTCDSNLEKDKE 626


>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
           theta, 150/170kDa [Homo sapiens]
          Length = 1382

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 28/95 (29%), Positives = 52/95 (54%), Gaps = 1/95 (1%)

Query: 462 IQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALE 521
           +  +Q  +E+KE RLE    +  +E LE++ A   + R   ++RL++E K + K +   E
Sbjct: 569 LARRQTIEERKE-RLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQE 627

Query: 522 FESKRREQVEQALKQATTSDSGLRMLKDTGIPDIE 556
            E  +++ V + L+Q   ++ G +  KD  I D+E
Sbjct: 628 HEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLE 662



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 26/87 (29%), Positives = 47/87 (54%), Gaps = 16/87 (18%)

Query: 461 RIQEKQIQQEKKELRLELYRERE-----------IRENLERQLAVELQSRTTM---QKRL 506
           R++E++ +Q K+E R+  YRE+E           ++E  ER+ A   +    +   Q+R+
Sbjct: 790 RLEERK-RQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERV 848

Query: 507 KK-EKKTKRKLQEALEFESKRREQVEQ 532
           KK E+  ++K Q  LE E + R + E+
Sbjct: 849 KKLEEVERKKRQRELEIEERERRREEE 875



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 6/98 (6%)

Query: 443 ETLLTNIQGLLKVALDNARIQEKQIQ-QEKKELRLELYREREIRENL---ERQLAVELQS 498
           E  +T +Q   + AL++     + ++ ++   +RL+  R+    E L   E +LA E  +
Sbjct: 730 EERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHN 789

Query: 499 RTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQ 536
           R   +KR +KE++     +E  E E +R E  EQ LK+
Sbjct: 790 RLEERKRQRKEERRITYYREKEEEEQRRAE--EQMLKE 825


>gi|67763814 death-inducing-protein [Homo sapiens]
          Length = 578

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 39/127 (30%), Positives = 66/127 (51%), Gaps = 17/127 (13%)

Query: 386 VSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETL 445
           ++ SP+  D   E  +E+P+++P   SP D  +L      PAG PG  I A  +      
Sbjct: 21  LAESPNASD--TECSDEIPLKVP-RTSPRDSEELRD----PAG-PGTLIMATGVQDFNRT 72

Query: 446 ----LTNIQGLLKVALDNARIQEKQIQQEKKE-----LRLELYREREIRENLERQLAVEL 496
               L  I+G L++AL      ++++++ ++E     LR EL RER+ R  LE+++   L
Sbjct: 73  EFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVL 132

Query: 497 QSRTTMQ 503
           ++RT  Q
Sbjct: 133 KARTEEQ 139


>gi|62244004 modulator of estrogen induced transcription isoform b
           [Homo sapiens]
          Length = 1016

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 23/82 (28%), Positives = 48/82 (58%), Gaps = 3/82 (3%)

Query: 454 KVALDNARIQEKQIQQEKKELRLE---LYREREIRENLERQLAVELQSRTTMQKRLKKEK 510
           ++ +   R + +++Q+E++ L +E   L RER  RE LER+     Q R    +R+ +E+
Sbjct: 629 RIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIARER 688

Query: 511 KTKRKLQEALEFESKRREQVEQ 532
           +  R+ Q+ L +E ++R  +++
Sbjct: 689 EELRRQQQQLRYEQEKRNSLKR 710



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 22/85 (25%), Positives = 50/85 (58%), Gaps = 5/85 (5%)

Query: 453 LKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKT 512
           L+ A++  R +E   ++ ++  R+ + RERE RE L+R    E +     +++L++E+  
Sbjct: 607 LRRAMELRRRREIAERERRERERIRIIREREERERLQR----ERERLEIERQKLERERME 662

Query: 513 KRKLQ-EALEFESKRREQVEQALKQ 536
           + +L+ E +  E +RR++ E+  ++
Sbjct: 663 RERLERERIRIEQERRKEAERIARE 687



 Score = 33.5 bits (75), Expect = 0.54
 Identities = 23/74 (31%), Positives = 43/74 (58%), Gaps = 3/74 (4%)

Query: 461 RIQEKQIQQEKKELRLELYREREI--RENLERQLAVELQSRTTMQKRLKKEKKTKRKLQE 518
           R++E  ++ E+    +EL R REI  RE  ER+    ++ R   ++RL++E++     ++
Sbjct: 596 RLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREE-RERLQRERERLEIERQ 654

Query: 519 ALEFESKRREQVEQ 532
            LE E   RE++E+
Sbjct: 655 KLERERMERERLER 668


>gi|63176611 modulator of estrogen induced transcription isoform a
           [Homo sapiens]
          Length = 1034

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 23/82 (28%), Positives = 48/82 (58%), Gaps = 3/82 (3%)

Query: 454 KVALDNARIQEKQIQQEKKELRLE---LYREREIRENLERQLAVELQSRTTMQKRLKKEK 510
           ++ +   R + +++Q+E++ L +E   L RER  RE LER+     Q R    +R+ +E+
Sbjct: 647 RIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIARER 706

Query: 511 KTKRKLQEALEFESKRREQVEQ 532
           +  R+ Q+ L +E ++R  +++
Sbjct: 707 EELRRQQQQLRYEQEKRNSLKR 728



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 22/85 (25%), Positives = 50/85 (58%), Gaps = 5/85 (5%)

Query: 453 LKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKT 512
           L+ A++  R +E   ++ ++  R+ + RERE RE L+R    E +     +++L++E+  
Sbjct: 625 LRRAMELRRRREIAERERRERERIRIIREREERERLQR----ERERLEIERQKLERERME 680

Query: 513 KRKLQ-EALEFESKRREQVEQALKQ 536
           + +L+ E +  E +RR++ E+  ++
Sbjct: 681 RERLERERIRIEQERRKEAERIARE 705



 Score = 33.5 bits (75), Expect = 0.54
 Identities = 23/74 (31%), Positives = 43/74 (58%), Gaps = 3/74 (4%)

Query: 461 RIQEKQIQQEKKELRLELYREREI--RENLERQLAVELQSRTTMQKRLKKEKKTKRKLQE 518
           R++E  ++ E+    +EL R REI  RE  ER+    ++ R   ++RL++E++     ++
Sbjct: 614 RLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREE-RERLQRERERLEIERQ 672

Query: 519 ALEFESKRREQVEQ 532
            LE E   RE++E+
Sbjct: 673 KLERERMERERLER 686


>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
          Length = 1219

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 59/285 (20%), Positives = 114/285 (40%), Gaps = 45/285 (15%)

Query: 281 GGAPTLNPLQQNHLLTNRLDLPFM--MMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAA 338
           GG P + P  Q  L      LP M    P P +     P++  M ++ ++  + ++  A 
Sbjct: 399 GGQPVVTPSVQPSLHPAHPALPQMTSQAPQPSVTGLQAPSAALMQVSSLDSHSAVSGNAQ 458

Query: 339 AAQIHSPLSR----AGTSVIKERIPESPS-PAPSLEENHRPGS------------QTSSH 381
           + Q ++ +        ++V  +  P  P  PAP  +  H  GS            Q ++ 
Sbjct: 459 SFQPYAGMQAYAYPQASAVTSQLQPVRPLYPAPLSQPPHFQGSGDMASFLMTEARQHNTE 518

Query: 382 TSSSVSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSS 441
              +VS    +MDH + ++EE      + K       L P  ++                
Sbjct: 519 IRMAVSKVADKMDHLMTKVEE------LQKHSAGNSMLIPSMSVTM-------------E 559

Query: 442 VETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTT 501
              +++NIQ +++   +N R++++ ++   K  R+E   ++ I E +ER      QS   
Sbjct: 560 TSMIMSNIQRIIQ---ENERLKQEILE---KSNRIEEQNDK-ISELIERNQRYVEQSNLM 612

Query: 502 MQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQATTSDSGLRM 546
           M+KR    +      Q  +    + + +V + L  AT   S L++
Sbjct: 613 MEKRNNSLQTATENTQARVLHAEQEKAKVTEELAAATAQVSHLQL 657


>gi|31377798 rabaptin, RAB GTPase binding effector protein 1 isoform
           1 [Homo sapiens]
          Length = 862

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 29/113 (25%), Positives = 61/113 (53%), Gaps = 10/113 (8%)

Query: 453 LKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKT 512
           LK  L+  ++++ Q++   +E   +L   +EI+ +LE QL  E  ++ T+++ + +EK  
Sbjct: 744 LKAELERIKVEKGQLESTLREKSQQLESLQEIKISLEEQLKKETAAKATVEQLMFEEKNK 803

Query: 513 KRKLQEALEF-ESKRREQVE---------QALKQATTSDSGLRMLKDTGIPDI 555
            ++LQ  L+  E  +R+ V+         + ++QA + +    +L DT + DI
Sbjct: 804 AQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQADSLERIRAILNDTKLTDI 856



 Score = 29.6 bits (65), Expect = 7.8
 Identities = 20/77 (25%), Positives = 42/77 (54%), Gaps = 2/77 (2%)

Query: 467 IQQEKKELRLELYREREIRENLERQL-AVELQSRTTMQKRLKKEKKTKRKLQEALEFESK 525
           +Q+E      +L R  ++  N E+QL  +++Q   T + ++KK +   R+  + LE   K
Sbjct: 518 LQKEVHNAGNKLGRRCDMCSNYEKQLQGIQIQEAET-RDQVKKLQLMLRQANDQLEKTMK 576

Query: 526 RREQVEQALKQATTSDS 542
            ++++E  +KQ++   S
Sbjct: 577 DKQELEDFIKQSSEDSS 593


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,012,654
Number of Sequences: 37866
Number of extensions: 1262453
Number of successful extensions: 10091
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 181
Number of HSP's successfully gapped in prelim test: 499
Number of HSP's that attempted gapping in prelim test: 6988
Number of HSP's gapped (non-prelim): 2981
length of query: 571
length of database: 18,247,518
effective HSP length: 108
effective length of query: 463
effective length of database: 14,157,990
effective search space: 6555149370
effective search space used: 6555149370
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.