Guide to the Human Genome
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Search of human proteins with 21361827

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21361827 methyltransferase like 3 [Homo sapiens]
         (580 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21361827 methyltransferase like 3 [Homo sapiens]                  1177   0.0  
gi|24308265 methyltransferase like 14 [Homo sapiens]                  103   3e-22
gi|145275206 methyltransferase like 4 [Homo sapiens]                   45   2e-04
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 37   0.038
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]    37   0.065
gi|124517695 ankyrin repeat domain 36B [Homo sapiens]                  37   0.065
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa...    36   0.11 
gi|4503337 dyskerin isoform 1 [Homo sapiens]                           36   0.11 
gi|81295796 HERV-H LTR-associating 3 isoform 2 [Homo sapiens]          35   0.14 
gi|33598950 podocalyxin-like isoform 2 precursor [Homo sapiens]        35   0.19 
gi|66277202 podocalyxin-like isoform 1 precursor [Homo sapiens]        35   0.19 
gi|37537701 SAPS domain family, member 2 [Homo sapiens]                35   0.19 
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]        34   0.42 
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po...    34   0.42 
gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]    34   0.42 
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]        33   0.55 
gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo ...    33   0.55 
gi|215599015 dyskerin isoform 2 [Homo sapiens]                         33   0.55 
gi|134304840 KIAA0319 [Homo sapiens]                                   33   0.72 
gi|4557719 DNA ligase I [Homo sapiens]                                 33   0.72 
gi|197313748 SET domain containing 2 [Homo sapiens]                    33   0.72 
gi|37675270 zinc finger protein 200 isoform 1 [Homo sapiens]           33   0.72 
gi|37675268 zinc finger protein 200 isoform 2 [Homo sapiens]           33   0.72 
gi|37675273 zinc finger protein 200 isoform 1 [Homo sapiens]           33   0.72 
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    33   0.72 
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             33   0.94 
gi|18379328 WW domain-containing adapter with a coiled-coil regi...    33   0.94 
gi|18379332 WW domain-containing adapter with a coiled-coil regi...    33   0.94 
gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens]          32   1.2  
gi|20149626 pleckstrin homology domain containing, family O memb...    32   1.2  

>gi|21361827 methyltransferase like 3 [Homo sapiens]
          Length = 580

 Score = 1177 bits (3046), Expect = 0.0
 Identities = 580/580 (100%), Positives = 580/580 (100%)

Query: 1   MSDTWSSIQAHKKQLDSLRERLQRRRKQDSGHLDLRNPEAALSPTFRSDSPVPTAPTSGG 60
           MSDTWSSIQAHKKQLDSLRERLQRRRKQDSGHLDLRNPEAALSPTFRSDSPVPTAPTSGG
Sbjct: 1   MSDTWSSIQAHKKQLDSLRERLQRRRKQDSGHLDLRNPEAALSPTFRSDSPVPTAPTSGG 60

Query: 61  PKPSTASAVPELATDPELEKKLLHHLSDLALTLPTDAVSICLAISTPDAPATQDGVESLL 120
           PKPSTASAVPELATDPELEKKLLHHLSDLALTLPTDAVSICLAISTPDAPATQDGVESLL
Sbjct: 61  PKPSTASAVPELATDPELEKKLLHHLSDLALTLPTDAVSICLAISTPDAPATQDGVESLL 120

Query: 121 QKFAAQELIEVKRGLLQDDAHPTLVTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRRA 180
           QKFAAQELIEVKRGLLQDDAHPTLVTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRRA
Sbjct: 121 QKFAAQELIEVKRGLLQDDAHPTLVTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRRA 180

Query: 181 EQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSK 240
           EQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSK
Sbjct: 181 EQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSK 240

Query: 241 KVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFR 300
           KVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFR
Sbjct: 241 KVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFR 300

Query: 301 RIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDACMDSEAPGSKDHTPSQELALTQSVG 360
           RIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDACMDSEAPGSKDHTPSQELALTQSVG
Sbjct: 301 RIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDACMDSEAPGSKDHTPSQELALTQSVG 360

Query: 361 GDSSADRLFPPQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRRLNIP 420
           GDSSADRLFPPQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRRLNIP
Sbjct: 361 GDSSADRLFPPQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRRLNIP 420

Query: 421 VLQDDGFLFLWVTGRAMELGRECLNLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGK 480
           VLQDDGFLFLWVTGRAMELGRECLNLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGK
Sbjct: 421 VLQDDGFLFLWVTGRAMELGRECLNLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGK 480

Query: 481 EHCLVGVKGNPQGFNQGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNV 540
           EHCLVGVKGNPQGFNQGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNV
Sbjct: 481 EHCLVGVKGNPQGFNQGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNV 540

Query: 541 QPNWITLGNQLDGIHLLDPDVVARFKQRYPDGIISKPKNL 580
           QPNWITLGNQLDGIHLLDPDVVARFKQRYPDGIISKPKNL
Sbjct: 541 QPNWITLGNQLDGIHLLDPDVVARFKQRYPDGIISKPKNL 580


>gi|24308265 methyltransferase like 14 [Homo sapiens]
          Length = 456

 Score =  103 bits (258), Expect = 3e-22
 Identities = 64/199 (32%), Positives = 102/199 (51%), Gaps = 17/199 (8%)

Query: 370 PPQWICCDIRYLDV-SILGKFAVVMADPPWDIHMELPYGTLTD-----DEMRRLNIP-VL 422
           PP ++  DI   D+  +  KF V++ +PP + +      T  +     D++ +L I  + 
Sbjct: 166 PPMYLQADIEAFDIRELTPKFDVILLEPPLEEYYRETGITANEKCWTWDDIMKLEIDEIA 225

Query: 423 QDDGFLFLWV-TGRAMELGRECLNLWGYERVDEIIWVKTNQLQ-RIIRTGRTGHWLNHGK 480
               F+FLW  +G  ++LGR CL  WGY R ++I W+KTN+      +T          K
Sbjct: 226 APRSFIFLWCGSGEGLDLGRVCLRKWGYRRCEDICWIKTNKNNPGKTKTLDPKAVFQRTK 285

Query: 481 EHCLVGVKGNPQGFNQG------LDCDVIVAEVRSTSH--KPDEIYGMIERLSPGTRKIE 532
           EHCL+G+KG  +    G      +D D+I+ E     +  KP EI+ +IE    G R++ 
Sbjct: 286 EHCLMGIKGTVKRSTDGDFIHANVDIDLIITEEPEIGNIEKPVEIFHIIEHFCLGRRRLH 345

Query: 533 LFGRPHNVQPNWITLGNQL 551
           LFGR   ++P W+T+G  L
Sbjct: 346 LFGRDSTIRPGWLTVGPTL 364


>gi|145275206 methyltransferase like 4 [Homo sapiens]
          Length = 472

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 46/178 (25%), Positives = 72/178 (40%), Gaps = 17/178 (9%)

Query: 389 FAVVMADPPW---DIHMELPYGTLTDDEMRRLNIPVLQDDGFLFL-WVTGRAMEL---GR 441
           F V++ DPPW    +     Y  L+  +++++ IP L     L + WVT R   L     
Sbjct: 281 FDVIVIDPPWQNKSVKRSNRYSYLSPLQIQQIPIPKLAAPNCLLVTWVTNRQKHLRFIKE 340

Query: 442 ECLNLWGYERVDEIIWVKTNQLQRII-------RTGRTGHWLNHGKEHCLVGVKGNPQGF 494
           E    W  E V E  WVK       +       +    G  L   +E   + ++      
Sbjct: 341 ELYPSWSVEVVAEWHWVKITNSGEFVFPLDSPHKKPYEGLILGRVQEKTALPLRNADVNV 400

Query: 495 NQGLDCDVIVA-EVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQL 551
               D  +IV+      SHKP     + + + P    +ELF R  N+QP W + GN++
Sbjct: 401 LPIPDHKLIVSVPCTLHSHKPPLAEVLKDYIKPDGEYLELFAR--NLQPGWTSWGNEV 456


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 37.4 bits (85), Expect = 0.038
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 2/91 (2%)

Query: 225  IESLLNQQSTKEQQSKKVSQEILELL--NTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKE 282
            +E L +Q + KE+Q K +S+ +LEL    T  A+E+ I    +      VQ+  D  T+E
Sbjct: 1727 VERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRHTRE 1786

Query: 283  ECMKASDADRPCRKLHFRRIINKHTDESLGD 313
               +  D +    KL      +K+ + SL D
Sbjct: 1787 LKTQVEDLNENLLKLKEALKTSKNRENSLTD 1817


>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
          Length = 710

 Score = 36.6 bits (83), Expect = 0.065
 Identities = 37/140 (26%), Positives = 63/140 (45%), Gaps = 12/140 (8%)

Query: 132 KRGLLQDDAHPTLVTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRRAEQDST----TV 187
           K G +     P   T +D  K  + +    E K  G   GTV+ QK++A + +T    +V
Sbjct: 156 KSGTVSSQKQPASKTASD--KTDSALNTATEIKD-GLQCGTVSSQKQQALKATTDEEGSV 212

Query: 188 AAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSKKVSQEIL 247
           +  A+ +  G  S      K+PA K    A SD + +  S + ++    + S+ VS +  
Sbjct: 213 SNIATEIKDGEKSGTVSSQKKPALK----ATSD-EKDSFSNITREKKDGEISRTVSSQKP 267

Query: 248 ELLNTTTAKEQSIVEKFRSR 267
             L  T+ KE S++   R +
Sbjct: 268 PALKATSVKEDSVLNIAREK 287


>gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
          Length = 1121

 Score = 36.6 bits (83), Expect = 0.065
 Identities = 37/140 (26%), Positives = 63/140 (45%), Gaps = 12/140 (8%)

Query: 132 KRGLLQDDAHPTLVTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRRAEQDST----TV 187
           K G +     P   T +D  K  + +    E K  G   GTV+ QK++A + +T    +V
Sbjct: 121 KSGTVSSQKQPASKTASD--KTDSALNTATEIKD-GLQCGTVSSQKQQALKATTDEEGSV 177

Query: 188 AAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSKKVSQEIL 247
           +  A+ +  G  S      K+PA K    A SD + +  S + ++    + S+ VS +  
Sbjct: 178 SNIATEIKDGEKSGTVSSQKKPALK----ATSD-EKDSFSNITREKKDGEISRTVSSQKP 232

Query: 248 ELLNTTTAKEQSIVEKFRSR 267
             L  T+ KE S++   R +
Sbjct: 233 PALKATSVKEDSVLNIAREK 252



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 12/102 (11%)

Query: 163 KKGPGEVAGTVTGQKRRAEQ----DSTTVAAFASSLVSGLNSSASEPAKEPAKK---SRK 215
           K+GP  ++GTV+ QK+ AE+    +  +V+  A+ +  G  S    P K+ A+K    +K
Sbjct: 49  KEGP--ISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKK 106

Query: 216 HAASDVDLEI---ESLLNQQSTKEQQSKKVSQEILELLNTTT 254
            +  ++   I          S K+  SK  S +    LNT T
Sbjct: 107 VSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTAT 148


>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
           sapiens]
          Length = 631

 Score = 35.8 bits (81), Expect = 0.11
 Identities = 38/157 (24%), Positives = 70/157 (44%), Gaps = 8/157 (5%)

Query: 118 SLLQKFAAQELIEVKRGLLQDDAHPTLVTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQK 177
           S L  F ++E  E KRG++  DAH  +    D      M   V       E++ + T Q+
Sbjct: 243 SCLCYFGSEECKE-KRGIIPLDAHCCVEVLPDRDGKRCMF-CVKTANRTYEMSASDTRQR 300

Query: 178 RRAEQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQ 237
               Q+ T     A  L +   +S  +  K+  ++ R+        + E LL  Q  +E+
Sbjct: 301 ----QEWTAAIQMAIRLQAEGKTSLHKDLKQKRREQREQRERRRAAKEEELLRLQQLQEE 356

Query: 238 QSKKVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQE 274
           + +K+  + LELL     + + ++++   R R+Q +E
Sbjct: 357 KERKL--QELELLQEAQRQAERLLQEEEERRRSQHRE 391


>gi|4503337 dyskerin isoform 1 [Homo sapiens]
          Length = 514

 Score = 35.8 bits (81), Expect = 0.11
 Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 21/134 (15%)

Query: 124 AAQELIEVKRGLLQDDAHPTLVT-------YADHSKLSAMMGAVAE-KKGPGEVAGTVTG 175
           A+Q+ + +K+GLL     PT  T       Y D+S+ SA    VAE  K P  VA     
Sbjct: 386 ASQKKLMIKQGLLDKHGKPTDSTPATWKQEYVDYSE-SAKKEVVAEVVKAPQVVAEAAKT 444

Query: 176 QKRRAEQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLL---NQQ 232
            KR+ E +S +              +A +  K+  KKS+K   +   LE  +     +  
Sbjct: 445 AKRKRESESES---------DETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSD 495

Query: 233 STKEQQSKKVSQEI 246
           +TK+++ KK ++E+
Sbjct: 496 TTKKKKKKKKAKEV 509


>gi|81295796 HERV-H LTR-associating 3 isoform 2 [Homo sapiens]
          Length = 114

 Score = 35.4 bits (80), Expect = 0.14
 Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 18/107 (16%)

Query: 190 FASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSKKVSQEILEL 249
           F +     L  S SEP  E  + + +HA  DV  E++ +L+Q +  E   + V  ++  +
Sbjct: 2   FGACYKQPLKPSGSEPPAEECRMTPRHAGCDV-TEMQRILSQPTFTEHLLRAVCTKLANM 60

Query: 250 LNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRK 296
            +T+T                  +E C  G K + +KA +A R C++
Sbjct: 61  YSTST----------------DCREHCRRGMKAKQLKA-EAGRSCQR 90


>gi|33598950 podocalyxin-like isoform 2 precursor [Homo sapiens]
          Length = 526

 Score = 35.0 bits (79), Expect = 0.19
 Identities = 46/204 (22%), Positives = 73/204 (35%), Gaps = 22/204 (10%)

Query: 41  ALSPTFRSDSPVPTAPTSGGPKPSTASAVPELATDPELEKKLLHHLSDLALTLPTDAVSI 100
           ALS      S  P  P+S  P PS +    +  TD   +            T PT A S+
Sbjct: 6   ALSALLLLLSTPPLLPSSPSPSPSPSQNATQTTTDSSNK------------TAPTPASSV 53

Query: 101 CLAISTPDAPATQDGVESLLQKFAAQELI-EVKRGLLQDDAHPTLVTYADHSKLSAMMGA 159
            +        AT    +S +    A E++  VK   L   +     T         +   
Sbjct: 54  TIM-------ATDTAQQSTVPTSKANEILASVKATTLGVSSDSPGTTTLAQQVSGPVNTT 106

Query: 160 VAEKKGPGEVAGTVTGQKRRAEQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAAS 219
           VA   G G    T+   K     D+TTVA   S+  +  N+++S+   E    S   ++ 
Sbjct: 107 VARGGGSGNPTTTIESPKSTKSADTTTVA--TSTATAKPNTTSSQNGAEDTTNSGGKSSH 164

Query: 220 DVDLEIESLLNQQSTKEQQSKKVS 243
            V  ++ S   +  T    +  +S
Sbjct: 165 SVTTDLTSTKAEHLTTPHPTSPLS 188


>gi|66277202 podocalyxin-like isoform 1 precursor [Homo sapiens]
          Length = 558

 Score = 35.0 bits (79), Expect = 0.19
 Identities = 46/204 (22%), Positives = 73/204 (35%), Gaps = 22/204 (10%)

Query: 41  ALSPTFRSDSPVPTAPTSGGPKPSTASAVPELATDPELEKKLLHHLSDLALTLPTDAVSI 100
           ALS      S  P  P+S  P PS +    +  TD   +            T PT A S+
Sbjct: 6   ALSALLLLLSTPPLLPSSPSPSPSPSQNATQTTTDSSNK------------TAPTPASSV 53

Query: 101 CLAISTPDAPATQDGVESLLQKFAAQELI-EVKRGLLQDDAHPTLVTYADHSKLSAMMGA 159
            +        AT    +S +    A E++  VK   L   +     T         +   
Sbjct: 54  TIM-------ATDTAQQSTVPTSKANEILASVKATTLGVSSDSPGTTTLAQQVSGPVNTT 106

Query: 160 VAEKKGPGEVAGTVTGQKRRAEQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAAS 219
           VA   G G    T+   K     D+TTVA   S+  +  N+++S+   E    S   ++ 
Sbjct: 107 VARGGGSGNPTTTIESPKSTKSADTTTVA--TSTATAKPNTTSSQNGAEDTTNSGGKSSH 164

Query: 220 DVDLEIESLLNQQSTKEQQSKKVS 243
            V  ++ S   +  T    +  +S
Sbjct: 165 SVTTDLTSTKAEHLTTPHPTSPLS 188


>gi|37537701 SAPS domain family, member 2 [Homo sapiens]
          Length = 932

 Score = 35.0 bits (79), Expect = 0.19
 Identities = 18/50 (36%), Positives = 24/50 (48%)

Query: 61  PKPSTASAVPELATDPELEKKLLHHLSDLALTLPTDAVSICLAISTPDAP 110
           P P   +A P +A  PE    +   LS     +PT AVS  LA++ P  P
Sbjct: 847 PAPKEVTAAPAVAVPPEATVAITTALSKAGPAIPTPAVSSALAVAVPLGP 896


>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
          Length = 1524

 Score = 33.9 bits (76), Expect = 0.42
 Identities = 40/170 (23%), Positives = 70/170 (41%), Gaps = 13/170 (7%)

Query: 107 PDAPATQDGVESLLQKFAAQELIEVKRGLLQDDAHPTLVTYADHSKLSAMMGAVAEKKGP 166
           P + AT D  +S L   A +    ++ G +     P L    D       +  +A +   
Sbjct: 372 PASKATSDKTDSALN-IATEIKDGLQCGTVSSQKQPALKATTDEED---SVSNIATEIKD 427

Query: 167 GEVAGTVTGQKRRAEQDST----TVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVD 222
           GE +GTV+ QK+ A + +T    +V+  A+ +  G  S      K PA      A SD +
Sbjct: 428 GEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALT----ATSDEE 483

Query: 223 LEIESLLNQQSTKEQQSKKVSQEILELLNTTTAKEQSIVEKFRSRGRAQV 272
             + S+  +    E +S+ VS      L  T+ ++ S     R +   ++
Sbjct: 484 GSVLSIARENKDGE-KSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEI 532



 Score = 30.0 bits (66), Expect = 6.1
 Identities = 52/250 (20%), Positives = 95/250 (38%), Gaps = 28/250 (11%)

Query: 15  LDSLRERLQRRRKQDSGHLDLRNPEAALSPTFRSDSPVPTAPTSGGPKPSTASAVPELAT 74
           +DSL    +   +     L L+  + +     R     P    S   +P+      E AT
Sbjct: 222 MDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPA------EKAT 275

Query: 75  DPELEKKLLHHLSDLALTLPTDAVSICLAIST-PDAPATQDGVESLLQKFAAQELIEVKR 133
             + +      +S++A  +    +S  ++    P   AT D  +S+     +    E+K+
Sbjct: 276 SDDKDS-----VSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSV-----SNIATEIKK 325

Query: 134 GLLQDDAHPTLVTY--ADHSKLSAMMGAVAEKKGPGEVAGTVTGQKR---RAEQDSTTVA 188
           G       P   +       K  +++       G G+ +GTV+ QK+   +A  D T  A
Sbjct: 326 GQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGK-SGTVSSQKQPASKATSDKTDSA 384

Query: 189 A-FASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSKKVSQEIL 247
              A+ +  GL        K+PA K    A +D +  + ++  +    E+     SQ+  
Sbjct: 385 LNIATEIKDGLQCGTVSSQKQPALK----ATTDEEDSVSNIATEIKDGEKSGTVSSQKQP 440

Query: 248 ELLNTTTAKE 257
            L  TT  K+
Sbjct: 441 ALKATTDEKD 450


>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
           polyclonal antibodies [Homo sapiens]
          Length = 1430

 Score = 33.9 bits (76), Expect = 0.42
 Identities = 41/167 (24%), Positives = 67/167 (40%), Gaps = 14/167 (8%)

Query: 107 PDAPATQDGVESLLQKFAAQELIEVKRGLLQDDAHPTLVTYADHSKLSAMMGAVAEKKGP 166
           P + AT D  +S L   A +    ++ G +     P L    D       +  +A +   
Sbjct: 372 PPSKATSDKTDSALN-IATEIKDGLQCGTVSSQKQPALKATTDEED---SVSNIATEIKD 427

Query: 167 GEVAGTVTGQKRRAEQDST----TVAAFASSLVSGLNSSASEPAKEPAKKS---RKHAAS 219
           GE +GTV+ QK+ A + +T    +V   A+ +  G  S      K+PA K+    + + S
Sbjct: 428 GEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVS 487

Query: 220 DVDLEI---ESLLNQQSTKEQQSKKVSQEILELLNTTTAKEQSIVEK 263
            +  EI   E      S K+   K  S E     N T  K+   + +
Sbjct: 488 IIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISR 534



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 54/253 (21%), Positives = 98/253 (38%), Gaps = 27/253 (10%)

Query: 15  LDSLRERLQRRRKQDSGHLDLRNPEAALSPTFRSDSPVPTAPTSGGPKPSTASAVPELAT 74
           +DSL    +   +     L L+  + +     R     P    S   +P+      E AT
Sbjct: 222 MDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPA------EKAT 275

Query: 75  DPELEKKLLHHLSDLALTLPTDAVSICLAIST-PDAPATQDGVESLLQKFAAQELIEVKR 133
             + +      +S++A  +    +S  ++    P   AT D  +S+     +    E+K 
Sbjct: 276 SDDKDS-----VSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSV-----SNIATEIKE 325

Query: 134 GLLQDDAHPTLVT-YADHSKLSAMMGAVAEKKGPGEVAGTVTGQKR---RAEQDSTTVAA 189
           G       P   + +    K    +  +A +   G  +GTV+ QK+   +A  D T  A 
Sbjct: 326 GQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDKTDSAL 385

Query: 190 -FASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSKKVSQEILE 248
             A+ +  GL        K+PA K    A +D +  + ++  +    E +S  VS +   
Sbjct: 386 NIATEIKDGLQCGTVSSQKQPALK----ATTDEEDSVSNIATEIKDGE-KSGTVSSQKQP 440

Query: 249 LLNTTTAKEQSIV 261
            L  TT +E S++
Sbjct: 441 ALKATTDEEDSVL 453



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 37/135 (27%), Positives = 60/135 (44%), Gaps = 16/135 (11%)

Query: 132 KRGLLQDDAHPTLVTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRRAEQDST----TV 187
           K G +     P     +D  K  + +    E K  G   GTV+ QK+ A + +T    +V
Sbjct: 362 KSGTVSSQKQPPSKATSD--KTDSALNIATEIKD-GLQCGTVSSQKQPALKATTDEEDSV 418

Query: 188 AAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLN--QQSTKEQQSKKVSQE 245
           +  A+ +  G  S      K+PA K    A +D   E +S+LN   +    ++S+ VS +
Sbjct: 419 SNIATEIKDGEKSGTVSSQKQPALK----ATTD---EEDSVLNIATEIKDGEKSETVSSQ 471

Query: 246 ILELLNTTTAKEQSI 260
               L  TT +E S+
Sbjct: 472 KQPALKATTDEEDSV 486



 Score = 30.0 bits (66), Expect = 6.1
 Identities = 48/253 (18%), Positives = 95/253 (37%), Gaps = 28/253 (11%)

Query: 8   IQAHKKQLDSLRERLQRRRKQDSGHLDLRNPEAALSPTFRSDSPVPTAPTSGGPKPSTAS 67
           ++A + + DSL    + ++  +       + + AL  T   ++ VP   T    K    S
Sbjct: 578 LKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATE--TKDEQIS 635

Query: 68  AVPELATDPELEKKLLHHLSDLALTLPTD--------AVSICLAISTPDAPATQDGVESL 119
                   P L  K      D    +PT+         VS    ++       +D V ++
Sbjct: 636 GTVSSQKQPAL--KATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNI 693

Query: 120 LQKFAAQELIEVKRGLLQDDAHPTLVTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRR 179
             +    ++    RG +     P L    D       +  +A +   GE +GTV+ QK+ 
Sbjct: 694 ATEIKDGQI----RGTVSSQRQPALKATGDEKD---SVSNIAREIKDGEKSGTVSPQKQS 746

Query: 180 AE----QDSTTVAAFASSLVSGLNSSASEPAKEPAKKS---RKHAASDVDLEIESLLNQQ 232
           A+    +   ++   A+ +  G  S    P   P  K+    K++  +   +++ +  Q 
Sbjct: 747 AQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDV--QT 804

Query: 233 STKEQQSKKVSQE 245
           ST  +Q  +++ E
Sbjct: 805 STPAEQDLEMASE 817


>gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]
          Length = 753

 Score = 33.9 bits (76), Expect = 0.42
 Identities = 33/113 (29%), Positives = 49/113 (43%), Gaps = 19/113 (16%)

Query: 16  DSLRERLQRRRKQDSGHLDLR-NPEAALSPTFR------SDSPVPTAPTSGGPKPSTASA 68
           DS +ER   RRK  S       +P+A   P+ +      S +PVP + +S  P     S 
Sbjct: 640 DSAKERASSRRKGCSSPPPPEPSPQAPDGPSLQLPAQTFSSAPVPGSSSSTLPSSCEQSR 699

Query: 69  VPELATDPELEKKLLHHLSDLALTLPTDAVSICLAISTPDAPATQDGVESLLQ 121
             E  +DP+ E            TL    VS  L++ + D P+    +E+LLQ
Sbjct: 700 QAETPSDPQTE------------TLSAMDVSEFLSLQSLDTPSNLIPIEALLQ 740


>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
          Length = 948

 Score = 33.5 bits (75), Expect = 0.55
 Identities = 41/171 (23%), Positives = 67/171 (39%), Gaps = 22/171 (12%)

Query: 107 PDAPATQDGVESLLQKFAAQELIEVKRGLLQDDAHPTLVTYADHSKLSAMMGAVAEKKGP 166
           P + AT D  +S L   A +    ++ G +     P L    D       +  +A +   
Sbjct: 372 PASKATSDKTDSALN-IATEIKDGLQCGTVSSQKQPALKATTDEED---SVSNIATEIKD 427

Query: 167 GEVAGTVTGQKRRAEQDST----TVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVD 222
           GE +GTV+ QK+ A + +T    +V+  A+ +  G  S      K PA      A SD +
Sbjct: 428 GEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALT----ATSDEE 483

Query: 223 LEIESLLNQ----------QSTKEQQSKKVSQEILELLNTTTAKEQSIVEK 263
             + S+  +           S K+  SK  S E     N T  K+   + +
Sbjct: 484 GSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISR 534



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 6/54 (11%)

Query: 163 KKGPGEVAGTVTGQKRRAEQ----DSTTVAAFASSLVSGLNSSASEPAKEPAKK 212
           K+GP  ++GTV+ QK+ AE+    +  +V+  A+ +  G  S    P K+ A+K
Sbjct: 290 KEGP--ISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARK 341



 Score = 30.4 bits (67), Expect = 4.7
 Identities = 52/250 (20%), Positives = 95/250 (38%), Gaps = 28/250 (11%)

Query: 15  LDSLRERLQRRRKQDSGHLDLRNPEAALSPTFRSDSPVPTAPTSGGPKPSTASAVPELAT 74
           +DSL    +   +     L L+  + +     R     P    S   +P+      E AT
Sbjct: 222 MDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPA------EKAT 275

Query: 75  DPELEKKLLHHLSDLALTLPTDAVSICLAIST-PDAPATQDGVESLLQKFAAQELIEVKR 133
             + +      +S++A  +    +S  ++    P   AT D  +S+     +    E+K+
Sbjct: 276 SDDKDS-----VSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSV-----SNIATEIKK 325

Query: 134 GLLQDDAHPTLVTYAD--HSKLSAMMGAVAEKKGPGEVAGTVTGQKR---RAEQDSTTVA 188
           G       P   +       K  +++       G G+ +GTV+ QK+   +A  D T  A
Sbjct: 326 GQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGK-SGTVSSQKQPASKATSDKTDSA 384

Query: 189 A-FASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSKKVSQEIL 247
              A+ +  GL        K+PA K    A +D +  + ++  +    E+     SQ+  
Sbjct: 385 LNIATEIKDGLQCGTVSSQKQPALK----ATTDEEDSVSNIATEIKDGEKSGTVSSQKQP 440

Query: 248 ELLNTTTAKE 257
            L  TT  K+
Sbjct: 441 ALKATTDEKD 450


>gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo
           sapiens]
          Length = 399

 Score = 33.5 bits (75), Expect = 0.55
 Identities = 41/167 (24%), Positives = 67/167 (40%), Gaps = 14/167 (8%)

Query: 107 PDAPATQDGVESLLQKFAAQELIEVKRGLLQDDAHPTLVTYADHSKLSAMMGAVAEKKGP 166
           P + AT D  +S L   A +    ++ G +     P L    D       +  +A +   
Sbjct: 116 PASKATSDKTDSALN-IATEIKDGLQCGTVSSQKQPALKATTDEED---SVSNIATEIKD 171

Query: 167 GEVAGTVTGQKRRAEQDST----TVAAFASSLVSGLNSSASEPAKEPAKKS---RKHAAS 219
           GE +GTV+ QK+ A + +T    +V   A+ +  G  S      K+PA K+    + + S
Sbjct: 172 GEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVS 231

Query: 220 DVDLEI---ESLLNQQSTKEQQSKKVSQEILELLNTTTAKEQSIVEK 263
            +  EI   E      S K+   K  S E     N T  K+   + +
Sbjct: 232 IIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISR 278



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 37/135 (27%), Positives = 60/135 (44%), Gaps = 16/135 (11%)

Query: 132 KRGLLQDDAHPTLVTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRRAEQDST----TV 187
           K G +     P     +D  K  + +    E K  G   GTV+ QK+ A + +T    +V
Sbjct: 106 KSGTVSSQKQPASKATSD--KTDSALNIATEIKD-GLQCGTVSSQKQPALKATTDEEDSV 162

Query: 188 AAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLN--QQSTKEQQSKKVSQE 245
           +  A+ +  G  S      K+PA K    A +D   E +S+LN   +    ++S+ VS +
Sbjct: 163 SNIATEIKDGEKSGTVSSQKQPALK----ATTD---EEDSVLNIATEIKDGEKSETVSSQ 215

Query: 246 ILELLNTTTAKEQSI 260
               L  TT +E S+
Sbjct: 216 KQPALKATTDEEDSV 230



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 29/106 (27%), Positives = 49/106 (46%), Gaps = 9/106 (8%)

Query: 160 VAEKKGPGEVAGTVTGQKR---RAEQDSTTVAA-FASSLVSGLNSSASEPAKEPAKKSRK 215
           +A +   G  +GTV+ QK+   +A  D T  A   A+ +  GL        K+PA K   
Sbjct: 97  IATRITGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALK--- 153

Query: 216 HAASDVDLEIESLLNQQSTKEQQSKKVSQEILELLNTTTAKEQSIV 261
            A +D +  + ++  +    E +S  VS +    L  TT +E S++
Sbjct: 154 -ATTDEEDSVSNIATEIKDGE-KSGTVSSQKQPALKATTDEEDSVL 197


>gi|215599015 dyskerin isoform 2 [Homo sapiens]
          Length = 509

 Score = 33.5 bits (75), Expect = 0.55
 Identities = 36/128 (28%), Positives = 59/128 (46%), Gaps = 14/128 (10%)

Query: 124 AAQELIEVKRGLLQDDAHPTLVTYADHSK-LSAMMGAVAE-KKGPGEVAGTVTGQKRRAE 181
           A+Q+ + +K+GLL     PT  T A   +  SA    VAE  K P  VA      KR+ E
Sbjct: 386 ASQKKLMIKQGLLDKHGKPTDSTPATWKQDESAKKEVVAEVVKAPQVVAEAAKTAKRKRE 445

Query: 182 QDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLL---NQQSTKEQQ 238
            +S +              +A +  K+  KKS+K   +   LE  +     +  +TK+++
Sbjct: 446 SESES---------DETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKK 496

Query: 239 SKKVSQEI 246
            KK ++E+
Sbjct: 497 KKKKAKEV 504


>gi|134304840 KIAA0319 [Homo sapiens]
          Length = 1072

 Score = 33.1 bits (74), Expect = 0.72
 Identities = 29/101 (28%), Positives = 43/101 (42%), Gaps = 3/101 (2%)

Query: 36  RNPEAALSPTFRSDSPVPTAPTSGGPKPSTASAVP-ELATDPELEKKLLHHLSD-LALTL 93
           ++P   ++P     S +PT PTS  P  ST S +P    T P   K+L     D L +TL
Sbjct: 289 KSPVLTVTPGSTEHS-IPTPPTSAAPSESTPSELPISPTTAPRTVKELTVSAGDNLIITL 347

Query: 94  PTDAVSICLAISTPDAPATQDGVESLLQKFAAQELIEVKRG 134
           P + V +   ++      T    E  L         E+K+G
Sbjct: 348 PDNEVELKAFVAPAPPVETTYNYEWNLISHPTDYQGEIKQG 388


>gi|4557719 DNA ligase I [Homo sapiens]
          Length = 919

 Score = 33.1 bits (74), Expect = 0.72
 Identities = 23/95 (24%), Positives = 39/95 (41%), Gaps = 4/95 (4%)

Query: 158 GAVAEK----KGPGEVAGTVTGQKRRAEQDSTTVAAFASSLVSGLNSSASEPAKEPAKKS 213
           G V+E     K PG  A  V G +   E ++ + A      +     S   PA  P   +
Sbjct: 44  GVVSESDSPVKRPGRKAARVLGSEGEEEDEALSPAKGQKPALDCSQVSPPRPATSPENNA 103

Query: 214 RKHAASDVDLEIESLLNQQSTKEQQSKKVSQEILE 248
                S +D     +  +++ ++Q  K+  QE+LE
Sbjct: 104 SLSDTSPMDSSPSGIPKRRTARKQLPKRTIQEVLE 138


>gi|197313748 SET domain containing 2 [Homo sapiens]
          Length = 2564

 Score = 33.1 bits (74), Expect = 0.72
 Identities = 59/246 (23%), Positives = 88/246 (35%), Gaps = 26/246 (10%)

Query: 40  AALSPTFRSDSPVPTAPTSGGPKPSTASAVPELATDPELEKKLLHH-----LSDLALTLP 94
           A L       + V + P+S  P P  A A    +  P  E   L H     L    + LP
Sbjct: 171 APLPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLP 230

Query: 95  TDAV-------SICLAISTPDAPATQDGVESLLQKFAAQELIE-VKRGLLQDDAH-PTLV 145
            D          I +   + +A   QD + + L++   Q L E       ++D+H     
Sbjct: 231 VDVAVRSLKEPPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKDE 290

Query: 146 TYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRRAEQDSTTVAAFASSLVSGLNSSASEP 205
              D SK+S        KK   +  G   G    +E D  +V   +S     L  SAS  
Sbjct: 291 EIPDSSKISLSCKKTGSKKKSSQSEGIFLG----SESDEDSVRTSSSQRSHDLKFSAS-- 344

Query: 206 AKEPAKKSRKHAASDVDLEIESLLNQQSTK-EQQSKKVSQEILELLNTTTAKEQSIVEKF 264
                +K R    S   L+ E L     +K ++  K  S   LE  +T     +   E+ 
Sbjct: 345 ----IEKERDFKKSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLE-RDTRYVSSRCRSERE 399

Query: 265 RSRGRA 270
           R R R+
Sbjct: 400 RRRSRS 405


>gi|37675270 zinc finger protein 200 isoform 1 [Homo sapiens]
          Length = 395

 Score = 33.1 bits (74), Expect = 0.72
 Identities = 19/74 (25%), Positives = 37/74 (50%), Gaps = 1/74 (1%)

Query: 174 TGQKRRAEQDSTTVAAFASSLVSGLNSSASEPAKEPAK-KSRKHAASDVDLEIESLLNQQ 232
           T Q    ++D ++V       V+G N    +P +EP + +  +  +SD D    SL++QQ
Sbjct: 136 TQQLTSEKEDDSSVGEMMLLAVNGSNPEGEDPEREPVENEDYREKSSDDDEMDSSLVSQQ 195

Query: 233 STKEQQSKKVSQEI 246
               Q+ ++++  I
Sbjct: 196 PPDNQEKERLNTSI 209


>gi|37675268 zinc finger protein 200 isoform 2 [Homo sapiens]
          Length = 394

 Score = 33.1 bits (74), Expect = 0.72
 Identities = 19/74 (25%), Positives = 37/74 (50%), Gaps = 1/74 (1%)

Query: 174 TGQKRRAEQDSTTVAAFASSLVSGLNSSASEPAKEPAK-KSRKHAASDVDLEIESLLNQQ 232
           T Q    ++D ++V       V+G N    +P +EP + +  +  +SD D    SL++QQ
Sbjct: 135 TQQLTSEKEDDSSVGEMMLLAVNGSNPEGEDPEREPVENEDYREKSSDDDEMDSSLVSQQ 194

Query: 233 STKEQQSKKVSQEI 246
               Q+ ++++  I
Sbjct: 195 PPDNQEKERLNTSI 208


>gi|37675273 zinc finger protein 200 isoform 1 [Homo sapiens]
          Length = 395

 Score = 33.1 bits (74), Expect = 0.72
 Identities = 19/74 (25%), Positives = 37/74 (50%), Gaps = 1/74 (1%)

Query: 174 TGQKRRAEQDSTTVAAFASSLVSGLNSSASEPAKEPAK-KSRKHAASDVDLEIESLLNQQ 232
           T Q    ++D ++V       V+G N    +P +EP + +  +  +SD D    SL++QQ
Sbjct: 136 TQQLTSEKEDDSSVGEMMLLAVNGSNPEGEDPEREPVENEDYREKSSDDDEMDSSLVSQQ 195

Query: 233 STKEQQSKKVSQEI 246
               Q+ ++++  I
Sbjct: 196 PPDNQEKERLNTSI 209


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 33.1 bits (74), Expect = 0.72
 Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 1/54 (1%)

Query: 197  GLNSSASEPAKEPAK-KSRKHAASDVDLEIESLLNQQSTKEQQSKKVSQEILEL 249
            G   SA++P+  PA+ +S K A S +  + + LL +    +QQ  +++QEI EL
Sbjct: 2861 GKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITEL 2914


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 32.7 bits (73), Expect = 0.94
 Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 3/79 (3%)

Query: 37   NPEAALSPTFRSDSPVPTAPTSGGP-KPSTASAVPELATDPELEKKLLHHLSDLALTLPT 95
            +P AA+ P     SP    PT   P  P+ A   PE  T P          +  A  +PT
Sbjct: 1028 SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1087

Query: 96   --DAVSICLAISTPDAPAT 112
              +  S   A+ TP+ P +
Sbjct: 1088 PEEPTSPAAAVPTPEEPTS 1106



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 3/79 (3%)

Query: 37   NPEAALSPTFRSDSPVPTAPTSGGP-KPSTASAVPELATDPELEKKLLHHLSDLALTLPT 95
            +P AA+       SP    PT   P  P+ A   PE  T P          +  A  +PT
Sbjct: 1041 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1100

Query: 96   --DAVSICLAISTPDAPAT 112
              +  S   A+ TP+ PA+
Sbjct: 1101 PEEPTSPAAAVPTPEEPAS 1119



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 3/79 (3%)

Query: 37   NPEAALSPTFRSDSPVPTAPTSGGP-KPSTASAVPELATDPELEKKLLHHLSDLALTLPT 95
            +P AA+       SP    PT   P  P+ A   PE  T P          +  A  +PT
Sbjct: 1054 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1113

Query: 96   --DAVSICLAISTPDAPAT 112
              +  S   A+ TP+ PA+
Sbjct: 1114 PEEPASPAAAVPTPEEPAS 1132



 Score = 30.0 bits (66), Expect = 6.1
 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 5/92 (5%)

Query: 38   PEAALSPTFRSDSPVPTAPTSGGPKPSTASAV--PELATDPELEKKLLHH--LSDLALTL 93
            P A ++      SP  + PTS  P  S A+AV  PE  T P      L     S  A+  
Sbjct: 1205 PAAMVATLEEFTSPAASVPTSEEPA-SLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLT 1263

Query: 94   PTDAVSICLAISTPDAPATQDGVESLLQKFAA 125
            P +  S   ++ TP+ PA+     S L++ A+
Sbjct: 1264 PEELSSPAASVPTPEEPASPAAAVSNLEEPAS 1295


>gi|18379328 WW domain-containing adapter with a coiled-coil region
           isoform 1 [Homo sapiens]
          Length = 647

 Score = 32.7 bits (73), Expect = 0.94
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 5/84 (5%)

Query: 40  AALSPTFRSDSPVPTAPTSGGPKPSTASAVPELATDPELEKKLLHHLSDLALTLPTDAVS 99
           + L+PT    S  PT+ ++    P   S +P L  DP L ++LL  L    L L    V 
Sbjct: 328 SGLNPT----SAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPAL-QATLQLNNSNVD 382

Query: 100 ICLAISTPDAPATQDGVESLLQKF 123
           I        A  TQ  ++S++ KF
Sbjct: 383 ISKINEVLTAAVTQASLQSIIHKF 406


>gi|18379332 WW domain-containing adapter with a coiled-coil region
           isoform 3 [Homo sapiens]
          Length = 544

 Score = 32.7 bits (73), Expect = 0.94
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 5/84 (5%)

Query: 40  AALSPTFRSDSPVPTAPTSGGPKPSTASAVPELATDPELEKKLLHHLSDLALTLPTDAVS 99
           + L+PT    S  PT+ ++    P   S +P L  DP L ++LL  L    L L    V 
Sbjct: 225 SGLNPT----SAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPAL-QATLQLNNSNVD 279

Query: 100 ICLAISTPDAPATQDGVESLLQKF 123
           I        A  TQ  ++S++ KF
Sbjct: 280 ISKINEVLTAAVTQASLQSIIHKF 303


>gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens]
          Length = 903

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 8/78 (10%)

Query: 39  EAALSPTFRSDSPVPTAPTSGGPKPST-ASAVPELATDPELEKK---LLHHL---SDLAL 91
           EAA++P   +  P+P  P  G P P T  S +  L + P  + K     HH+   S LAL
Sbjct: 409 EAAVAPP-DAGLPLPGLPAEGSPPPKTYVSCLKSLLSSPTKDSKPNISAHHISLASCLAL 467

Query: 92  TLPTDAVSICLAISTPDA 109
           T P++ +     I   DA
Sbjct: 468 TTPSEELPDRAGILVEDA 485


>gi|20149626 pleckstrin homology domain containing, family O member
           1 [Homo sapiens]
          Length = 409

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 166 PGEVAGTVTGQKRRAEQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEI 225
           PG+++       R+ E+    +A      V GL     + AK+P +      +  + LE 
Sbjct: 302 PGQLSRIQDLVARKLEETQELLAE-----VQGLGDGKRK-AKDPPRSPPDSESEQLLLET 355

Query: 226 ESLLNQQSTKEQQSKKVSQEILEL 249
           E LL + S+   Q+K+V QE+ EL
Sbjct: 356 ERLLGEASSNWSQAKRVLQEVREL 379


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,522,670
Number of Sequences: 37866
Number of extensions: 1115274
Number of successful extensions: 5321
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 5221
Number of HSP's gapped (non-prelim): 149
length of query: 580
length of database: 18,247,518
effective HSP length: 108
effective length of query: 472
effective length of database: 14,157,990
effective search space: 6682571280
effective search space used: 6682571280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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