Guide to the Human Genome
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Name: METTL3 Sequence: fasta or formatted (580aa) NCBI GI: 21361827
Description:

methyltransferase like 3

Referenced in:

Additional Enzymes and Related Sequences
RNA Editing and Other RNA Modifications

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.2         42           2
 C cysteine            2.2         13           2
 D aspartate           7.4         43           2
 E glutamate           6.6         38           2
 F phenylalanine       2.6         15           1
 G glycine             6.2         36           2
 H histidine           3.3         19           2
 I isoleucine          4.7         27           2
 K lysine              6.2         36           2
 L leucine            10.0         58           2
 M methionine          1.9         11           2
 N asparagine          2.8         16           1
 P proline             5.7         33           2
 Q glutamine           5.0         29           2
 R arginine            5.9         34           3
 S serine              7.9         46           2
 T threonine           6.0         35           3
 V valine              5.5         32           2
 W tryptophan          1.4          8           1
 Y tyrosine            1.6          9           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   methyltransferase like 3 
METTL14               0.068   methyltransferase like 14 
METTL4                0.017   methyltransferase like 4 
CEP290                0.010   centrosomal protein 290kDa 
LOC100133923          0.010   PREDICTED: similar to UPF0634 protein C 
ANKRD36B              0.010   ankyrin repeat domain 36B 
DEF6                  0.010   differentially expressed in FDCP 6 homolog 
DKC1                  0.010   dyskerin isoform 1 
HHLA3                 0.009   HERV-H LTR-associating 3 isoform 2 
PODXL                 0.009   podocalyxin-like isoform 2 precursor 
PODXL                 0.009   podocalyxin-like isoform 1 precursor 
SAPS2                 0.009   SAPS domain family, member 2 
ANKRD36               0.008   PREDICTED: ankyrin repeat domain 36 
LOC400986             0.008   PREDICTED: protein immuno-reactive with anti-PTH po...
MTF1                  0.008   metal-regulatory transcription factor 1 
ANKRD36               0.007   PREDICTED: ankyrin repeat domain 36 
LOC100289777          0.007   PREDICTED: hypothetical protein XP_002348316 
DKC1                  0.007   dyskerin isoform 2 
KIAA0319              0.007   KIAA0319 
LIG1                  0.007   DNA ligase I 
SETD2                 0.007   SET domain containing 2 
ZNF200                0.007   zinc finger protein 200 isoform 1 
ZNF200                0.007   zinc finger protein 200 isoform 2 
ZNF200                0.007   zinc finger protein 200 isoform 1 
GOLGB1                0.007   golgi autoantigen, golgin subfamily b, macrogolgin ...
KIAA0754              0.007   hypothetical protein LOC643314 
WAC                   0.007   WW domain-containing adapter with a coiled-coil regi...
WAC                   0.007   WW domain-containing adapter with a coiled-coil regi...
AKAP1                 0.006   A-kinase anchor protein 1 precursor 
PLEKHO1               0.006   pleckstrin homology domain containing, family O memb...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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