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Search of human proteins with 21361787
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361787 tetratricopeptide repeat domain 17 [Homo sapiens]
(1141 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361787 tetratricopeptide repeat domain 17 [Homo sapiens] 2324 0.0
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 46 2e-04
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 46 2e-04
gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens] 44 9e-04
gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens] 44 9e-04
gi|31377634 guanylate binding protein 4 [Homo sapiens] 44 0.001
gi|118766328 transmembrane and tetratricopeptide repeat containi... 40 0.013
gi|118766330 transmembrane and tetratricopeptide repeat containi... 40 0.013
gi|148234215 guanylate binding protein 4-like [Homo sapiens] 40 0.017
gi|118402596 cell division cycle protein 23 [Homo sapiens] 39 0.022
gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sap... 36 0.18
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 36 0.18
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 36 0.18
gi|4504063 golgin 97 [Homo sapiens] 36 0.18
gi|221139761 zinc finger protein 853 [Homo sapiens] 36 0.24
gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi... 35 0.31
gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi... 35 0.31
gi|110347429 mediator complex subunit 12 [Homo sapiens] 35 0.31
gi|153085395 histone deacetylase 4 [Homo sapiens] 35 0.41
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 35 0.53
gi|32698688 citron [Homo sapiens] 35 0.53
gi|60685231 tetratricopeptide repeat domain 7B [Homo sapiens] 35 0.53
gi|157502225 Janus kinase and microtubule interacting protein 3 ... 34 0.69
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 34 0.69
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 34 0.69
gi|109255239 centrosomal protein 63 isoform b [Homo sapiens] 34 0.69
gi|22095367 centrosomal protein 63 isoform a [Homo sapiens] 34 0.69
gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo s... 34 0.69
gi|156231067 TBC1 domain family, member 8 [Homo sapiens] 34 0.91
gi|21735550 mitogen-activated protein kinase kinase kinase 10 [H... 34 0.91
>gi|21361787 tetratricopeptide repeat domain 17 [Homo sapiens]
Length = 1141
Score = 2324 bits (6023), Expect = 0.0
Identities = 1141/1141 (100%), Positives = 1141/1141 (100%)
Query: 1 MAAAVGVRGRYELPPCSGPGWLLSLSALLSVAARGAFATTHWVVTEDGKIQQQVDSPMNL 60
MAAAVGVRGRYELPPCSGPGWLLSLSALLSVAARGAFATTHWVVTEDGKIQQQVDSPMNL
Sbjct: 1 MAAAVGVRGRYELPPCSGPGWLLSLSALLSVAARGAFATTHWVVTEDGKIQQQVDSPMNL 60
Query: 61 KHPHDLVILMRQEATVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVP 120
KHPHDLVILMRQEATVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVP
Sbjct: 61 KHPHDLVILMRQEATVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVP 120
Query: 121 LGDLDLYDGTYITLESKDISPEDYIDTESPVPPDPEQPDCTKILELPYSIHAFQHLRGVQ 180
LGDLDLYDGTYITLESKDISPEDYIDTESPVPPDPEQPDCTKILELPYSIHAFQHLRGVQ
Sbjct: 121 LGDLDLYDGTYITLESKDISPEDYIDTESPVPPDPEQPDCTKILELPYSIHAFQHLRGVQ 180
Query: 181 ERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGLQKNTSSWVLYNMASFYWRIKN 240
ERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGLQKNTSSWVLYNMASFYWRIKN
Sbjct: 181 ERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGLQKNTSSWVLYNMASFYWRIKN 240
Query: 241 EPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAALDDSDFFTSYYT 300
EPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAALDDSDFFTSYYT
Sbjct: 241 EPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAALDDSDFFTSYYT 300
Query: 301 LGNIYAMLGEYNHSVLCYDHALQARPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLN 360
LGNIYAMLGEYNHSVLCYDHALQARPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLN
Sbjct: 301 LGNIYAMLGEYNHSVLCYDHALQARPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLN 360
Query: 361 ELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHS 420
ELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHS
Sbjct: 361 ELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHS 420
Query: 421 LHCQWDQPVRYHRGDIFENVDYVQFGEDSSTSSMMSVNFDVQSNQSDINDSVKSSPVAHS 480
LHCQWDQPVRYHRGDIFENVDYVQFGEDSSTSSMMSVNFDVQSNQSDINDSVKSSPVAHS
Sbjct: 421 LHCQWDQPVRYHRGDIFENVDYVQFGEDSSTSSMMSVNFDVQSNQSDINDSVKSSPVAHS 480
Query: 481 ILWIWGRDSDAYRDKQHILWPKRADCTESYPRVPVGGELPTYFLPPENKGLRIHELSSDD 540
ILWIWGRDSDAYRDKQHILWPKRADCTESYPRVPVGGELPTYFLPPENKGLRIHELSSDD
Sbjct: 481 ILWIWGRDSDAYRDKQHILWPKRADCTESYPRVPVGGELPTYFLPPENKGLRIHELSSDD 540
Query: 541 YSTEEEAQTPDCSITDFRKSHTLSYLVKELEVRMDLKAKMPDDHARKILLSRINNYTIPE 600
YSTEEEAQTPDCSITDFRKSHTLSYLVKELEVRMDLKAKMPDDHARKILLSRINNYTIPE
Sbjct: 541 YSTEEEAQTPDCSITDFRKSHTLSYLVKELEVRMDLKAKMPDDHARKILLSRINNYTIPE 600
Query: 601 EEIGSFLFHAINKPNAPIWLILNEAGLYWRAVGNSTFAIACLQRALNLAPLQYQDVPLVN 660
EEIGSFLFHAINKPNAPIWLILNEAGLYWRAVGNSTFAIACLQRALNLAPLQYQDVPLVN
Sbjct: 601 EEIGSFLFHAINKPNAPIWLILNEAGLYWRAVGNSTFAIACLQRALNLAPLQYQDVPLVN 660
Query: 661 LANLLIHYGLHLDATKLLLQALAINSSEPLTFLSLGNAYLALKNISGALEAFRQALKLTT 720
LANLLIHYGLHLDATKLLLQALAINSSEPLTFLSLGNAYLALKNISGALEAFRQALKLTT
Sbjct: 661 LANLLIHYGLHLDATKLLLQALAINSSEPLTFLSLGNAYLALKNISGALEAFRQALKLTT 720
Query: 721 KCPECENSLKLIRCMQFYPFLYNITSSVCSGTVVEESNGSDEMENSDETKMSEEILALVD 780
KCPECENSLKLIRCMQFYPFLYNITSSVCSGTVVEESNGSDEMENSDETKMSEEILALVD
Sbjct: 721 KCPECENSLKLIRCMQFYPFLYNITSSVCSGTVVEESNGSDEMENSDETKMSEEILALVD 780
Query: 781 EFQQAWPLEGFGGALEMKGRRLDLQGIRVLKKGPQDGVARSSCYGDCRSEDDEATEWITF 840
EFQQAWPLEGFGGALEMKGRRLDLQGIRVLKKGPQDGVARSSCYGDCRSEDDEATEWITF
Sbjct: 781 EFQQAWPLEGFGGALEMKGRRLDLQGIRVLKKGPQDGVARSSCYGDCRSEDDEATEWITF 840
Query: 841 QVKRVKKPKGDHKKTPGKKVETGQIENGHRYQANLEITGPKVASPGPQGKKRDYQRLGWP 900
QVKRVKKPKGDHKKTPGKKVETGQIENGHRYQANLEITGPKVASPGPQGKKRDYQRLGWP
Sbjct: 841 QVKRVKKPKGDHKKTPGKKVETGQIENGHRYQANLEITGPKVASPGPQGKKRDYQRLGWP 900
Query: 901 SPDECLKLRWVELTAIVSTWLAVSSKNIDITEHIDFATPIQQPAMEPLCNGNLPTSMHTL 960
SPDECLKLRWVELTAIVSTWLAVSSKNIDITEHIDFATPIQQPAMEPLCNGNLPTSMHTL
Sbjct: 901 SPDECLKLRWVELTAIVSTWLAVSSKNIDITEHIDFATPIQQPAMEPLCNGNLPTSMHTL 960
Query: 961 DHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSM 1020
DHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSM
Sbjct: 961 DHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSM 1020
Query: 1021 AALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEI 1080
AALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEI
Sbjct: 1021 AALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEI 1080
Query: 1081 APHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKGRRS 1140
APHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKGRRS
Sbjct: 1081 APHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKGRRS 1140
Query: 1141 P 1141
P
Sbjct: 1141 P 1141
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 45.8 bits (107), Expect = 2e-04
Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 2/94 (2%)
Query: 1028 KGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVN 1087
KG +A DC AL P L +LANI +AV + A+E+ P FA
Sbjct: 296 KGSVAEAEDCYNTALRLCPTHADS--LNNLANIKREQGNIEEAVRLYRKALEVFPEFAAA 353
Query: 1088 HFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPA 1121
H L +V + ++AL+ Y+ +++ P F A
Sbjct: 354 HSNLASVLQQQGKLQEALMHYKEAIRISPTFADA 387
Score = 39.7 bits (91), Expect = 0.017
Identities = 26/103 (25%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
Query: 1026 RVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFA 1085
R +G ++A+ R+AL P +LA++L +A++ A+ I+P FA
Sbjct: 328 REQGNIEEAVRLYRKALEVFPEFA--AAHSNLASVLQQQGKLQEALMHYKEAIRISPTFA 385
Query: 1086 VNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTI 1128
+ +GN M++ + AL Y +++ P F A + + +I
Sbjct: 386 DAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASI 428
Score = 38.5 bits (88), Expect = 0.037
Identities = 34/138 (24%), Positives = 62/138 (44%), Gaps = 2/138 (1%)
Query: 984 LQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALH 1043
L NL + Q ++E+ K LE S A + +G+ ++A+ ++A+
Sbjct: 320 LNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIR 379
Query: 1044 YAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEK 1103
+P D ++ N L + A+ T A++I P FA H L +++ +
Sbjct: 380 ISP-TFADA-YSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPE 437
Query: 1104 ALVWYESTLKLQPEFVPA 1121
A+ Y + LKL+P+F A
Sbjct: 438 AIASYRTALKLKPDFPDA 455
Score = 36.2 bits (82), Expect = 0.18
Identities = 18/66 (27%), Positives = 37/66 (56%)
Query: 1054 LISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLK 1113
L+ L++I + + + +T+A++ P A + LGNVY + ++A+ Y L+
Sbjct: 48 LLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALR 107
Query: 1114 LQPEFV 1119
L+P+F+
Sbjct: 108 LKPDFI 113
Score = 34.7 bits (78), Expect = 0.53
Identities = 40/146 (27%), Positives = 60/146 (41%), Gaps = 10/146 (6%)
Query: 980 LTEVLQNLGKDQYPQQSLEQI--GTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDC 1037
L E NLG + L++ R A L+ + ++ AAL G + A+
Sbjct: 78 LAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALV--AAGDMEGAVQA 135
Query: 1038 LRQALHYAPHQMKDVPLI--SLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVY 1095
AL Y P D+ + L N+L +A A+E P+FAV LG V+
Sbjct: 136 YVSALQYNP----DLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVF 191
Query: 1096 VAMEEFEKALVWYESTLKLQPEFVPA 1121
A E A+ +E + L P F+ A
Sbjct: 192 NAQGEIWLAIHHFEKAVTLDPNFLDA 217
Score = 33.1 bits (74), Expect = 1.5
Identities = 46/195 (23%), Positives = 83/195 (42%), Gaps = 14/195 (7%)
Query: 600 EEEIGSFLFHAINKPN-APIWLILNEAGLYWRAVGNSTFAIACLQRALNLAPLQYQDVPL 658
EE +L +PN A W + G + A G AI ++A+ L P + D
Sbjct: 164 EEAKACYLKAIETQPNFAVAW---SNLGCVFNAQGEIWLAIHHFEKAVTLDP-NFLDA-Y 218
Query: 659 VNLANLLIHYGLHLDATKLLLQALAINSSEPLTFLSLGNAYLALKNISGALEAFRQALKL 718
+NL N+L + A L+AL+++ + + +L Y I A++ +R+A++L
Sbjct: 219 INLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIEL 278
Query: 719 TTKCPEC----ENSLKLIRCMQFYPFLYNITSSVC---SGTVVEESNGSDEMENSDE-TK 770
P+ N+LK + YN +C + ++ +N E N +E +
Sbjct: 279 QPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVR 338
Query: 771 MSEEILALVDEFQQA 785
+ + L + EF A
Sbjct: 339 LYRKALEVFPEFAAA 353
Score = 32.7 bits (73), Expect = 2.0
Identities = 25/111 (22%), Positives = 52/111 (46%), Gaps = 2/111 (1%)
Query: 622 LNEAGLYWRAVGNSTFAIACLQRALNLAPLQYQDVPLVNLANLLIHYGLHLDATKLLLQA 681
LN R GN A+ ++AL + P NLA++L G +A +A
Sbjct: 320 LNNLANIKREQGNIEEAVRLYRKALEVFP--EFAAAHSNLASVLQQQGKLQEALMHYKEA 377
Query: 682 LAINSSEPLTFLSLGNAYLALKNISGALEAFRQALKLTTKCPECENSLKLI 732
+ I+ + + ++GN ++++ GAL+ + +A+++ + ++L I
Sbjct: 378 IRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASI 428
Score = 31.6 bits (70), Expect = 4.5
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Query: 297 SYYTLGNIYAMLGEYNHSVLCYDHALQARPGF-EQAIKRKHAVLCQQKLEQKLEAQHRSL 355
+Y LGN+Y G+ ++ Y HAL+ +P F + I A++ +E ++A +L
Sbjct: 81 AYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSAL 140
Query: 356 Q 356
Q
Sbjct: 141 Q 141
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 45.8 bits (107), Expect = 2e-04
Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 2/94 (2%)
Query: 1028 KGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVN 1087
KG +A DC AL P L +LANI +AV + A+E+ P FA
Sbjct: 306 KGSVAEAEDCYNTALRLCPTHADS--LNNLANIKREQGNIEEAVRLYRKALEVFPEFAAA 363
Query: 1088 HFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPA 1121
H L +V + ++AL+ Y+ +++ P F A
Sbjct: 364 HSNLASVLQQQGKLQEALMHYKEAIRISPTFADA 397
Score = 39.7 bits (91), Expect = 0.017
Identities = 26/103 (25%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
Query: 1026 RVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFA 1085
R +G ++A+ R+AL P +LA++L +A++ A+ I+P FA
Sbjct: 338 REQGNIEEAVRLYRKALEVFPEFA--AAHSNLASVLQQQGKLQEALMHYKEAIRISPTFA 395
Query: 1086 VNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTI 1128
+ +GN M++ + AL Y +++ P F A + + +I
Sbjct: 396 DAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASI 438
Score = 38.5 bits (88), Expect = 0.037
Identities = 34/138 (24%), Positives = 62/138 (44%), Gaps = 2/138 (1%)
Query: 984 LQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALH 1043
L NL + Q ++E+ K LE S A + +G+ ++A+ ++A+
Sbjct: 330 LNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIR 389
Query: 1044 YAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEK 1103
+P D ++ N L + A+ T A++I P FA H L +++ +
Sbjct: 390 ISP-TFADA-YSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPE 447
Query: 1104 ALVWYESTLKLQPEFVPA 1121
A+ Y + LKL+P+F A
Sbjct: 448 AIASYRTALKLKPDFPDA 465
Score = 36.2 bits (82), Expect = 0.18
Identities = 18/66 (27%), Positives = 37/66 (56%)
Query: 1054 LISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLK 1113
L+ L++I + + + +T+A++ P A + LGNVY + ++A+ Y L+
Sbjct: 58 LLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALR 117
Query: 1114 LQPEFV 1119
L+P+F+
Sbjct: 118 LKPDFI 123
Score = 34.7 bits (78), Expect = 0.53
Identities = 40/146 (27%), Positives = 60/146 (41%), Gaps = 10/146 (6%)
Query: 980 LTEVLQNLGKDQYPQQSLEQI--GTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDC 1037
L E NLG + L++ R A L+ + ++ AAL G + A+
Sbjct: 88 LAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALV--AAGDMEGAVQA 145
Query: 1038 LRQALHYAPHQMKDVPLI--SLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVY 1095
AL Y P D+ + L N+L +A A+E P+FAV LG V+
Sbjct: 146 YVSALQYNP----DLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVF 201
Query: 1096 VAMEEFEKALVWYESTLKLQPEFVPA 1121
A E A+ +E + L P F+ A
Sbjct: 202 NAQGEIWLAIHHFEKAVTLDPNFLDA 227
Score = 33.1 bits (74), Expect = 1.5
Identities = 46/195 (23%), Positives = 83/195 (42%), Gaps = 14/195 (7%)
Query: 600 EEEIGSFLFHAINKPN-APIWLILNEAGLYWRAVGNSTFAIACLQRALNLAPLQYQDVPL 658
EE +L +PN A W + G + A G AI ++A+ L P + D
Sbjct: 174 EEAKACYLKAIETQPNFAVAW---SNLGCVFNAQGEIWLAIHHFEKAVTLDP-NFLDA-Y 228
Query: 659 VNLANLLIHYGLHLDATKLLLQALAINSSEPLTFLSLGNAYLALKNISGALEAFRQALKL 718
+NL N+L + A L+AL+++ + + +L Y I A++ +R+A++L
Sbjct: 229 INLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIEL 288
Query: 719 TTKCPEC----ENSLKLIRCMQFYPFLYNITSSVC---SGTVVEESNGSDEMENSDE-TK 770
P+ N+LK + YN +C + ++ +N E N +E +
Sbjct: 289 QPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVR 348
Query: 771 MSEEILALVDEFQQA 785
+ + L + EF A
Sbjct: 349 LYRKALEVFPEFAAA 363
Score = 32.7 bits (73), Expect = 2.0
Identities = 25/111 (22%), Positives = 52/111 (46%), Gaps = 2/111 (1%)
Query: 622 LNEAGLYWRAVGNSTFAIACLQRALNLAPLQYQDVPLVNLANLLIHYGLHLDATKLLLQA 681
LN R GN A+ ++AL + P NLA++L G +A +A
Sbjct: 330 LNNLANIKREQGNIEEAVRLYRKALEVFP--EFAAAHSNLASVLQQQGKLQEALMHYKEA 387
Query: 682 LAINSSEPLTFLSLGNAYLALKNISGALEAFRQALKLTTKCPECENSLKLI 732
+ I+ + + ++GN ++++ GAL+ + +A+++ + ++L I
Sbjct: 388 IRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASI 438
Score = 31.6 bits (70), Expect = 4.5
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Query: 297 SYYTLGNIYAMLGEYNHSVLCYDHALQARPGF-EQAIKRKHAVLCQQKLEQKLEAQHRSL 355
+Y LGN+Y G+ ++ Y HAL+ +P F + I A++ +E ++A +L
Sbjct: 91 AYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSAL 150
Query: 356 Q 356
Q
Sbjct: 151 Q 151
>gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens]
Length = 1123
Score = 43.9 bits (102), Expect = 9e-04
Identities = 34/89 (38%), Positives = 46/89 (51%), Gaps = 4/89 (4%)
Query: 339 LCQQKLEQKLEA--QHRSLQRTLNELKEYQKQHDHYLRQQEI-LEKHKLIQEEQILRNII 395
L +Q+L+Q+L A Q + LQ+ L E+QKQHDH RQ E+ L+KH Q+E +
Sbjct: 72 LREQQLQQELLALKQQQQLQKQLL-FAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQ 130
Query: 396 HETQMAKEAQLGNHQICRLVNQQHSLHCQ 424
E AK Q Q R +Q L Q
Sbjct: 131 QEMLAAKRQQELEQQRQREQQRQEELEKQ 159
Score = 33.9 bits (76), Expect = 0.91
Identities = 24/83 (28%), Positives = 44/83 (53%), Gaps = 7/83 (8%)
Query: 332 IKRKHAVLCQQKLEQKLEAQHRSLQRTLNELK---EYQKQHDHYLRQQEILEKHKLIQEE 388
+ R+H V Q+ L+Q+ E Q+ + K E ++Q ++QE LEK +L Q+
Sbjct: 106 LTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQL 165
Query: 389 QILRNIIHETQMAKEAQLGNHQI 411
ILRN + +KE+ + + ++
Sbjct: 166 LILRN----KEKSKESAIASTEV 184
>gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens]
Length = 1122
Score = 43.9 bits (102), Expect = 9e-04
Identities = 34/89 (38%), Positives = 46/89 (51%), Gaps = 4/89 (4%)
Query: 339 LCQQKLEQKLEA--QHRSLQRTLNELKEYQKQHDHYLRQQEI-LEKHKLIQEEQILRNII 395
L +Q+L+Q+L A Q + LQ+ L E+QKQHDH RQ E+ L+KH Q+E +
Sbjct: 71 LREQQLQQELLALKQQQQLQKQLL-FAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQ 129
Query: 396 HETQMAKEAQLGNHQICRLVNQQHSLHCQ 424
E AK Q Q R +Q L Q
Sbjct: 130 QEMLAAKRQQELEQQRQREQQRQEELEKQ 158
Score = 33.9 bits (76), Expect = 0.91
Identities = 24/83 (28%), Positives = 44/83 (53%), Gaps = 7/83 (8%)
Query: 332 IKRKHAVLCQQKLEQKLEAQHRSLQRTLNELK---EYQKQHDHYLRQQEILEKHKLIQEE 388
+ R+H V Q+ L+Q+ E Q+ + K E ++Q ++QE LEK +L Q+
Sbjct: 105 LTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQL 164
Query: 389 QILRNIIHETQMAKEAQLGNHQI 411
ILRN + +KE+ + + ++
Sbjct: 165 LILRN----KEKSKESAIASTEV 183
>gi|31377634 guanylate binding protein 4 [Homo sapiens]
Length = 640
Score = 43.5 bits (101), Expect = 0.001
Identities = 28/102 (27%), Positives = 60/102 (58%), Gaps = 12/102 (11%)
Query: 319 DHALQARPGFEQAIKRKHAVLCQQKLEQK--LEAQHRSLQRTLNEL-KEYQKQHDHYLRQ 375
+ A+ A ++A +++ +L +++ EQ+ +EAQ RS Q + ++ K+ +++ ++ LR+
Sbjct: 500 EKAIAAERAMKEAAEKEQELLREKQKEQQQMMEAQERSFQEYMAQMEKKLEEERENLLRE 559
Query: 376 QEILEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRLVNQ 417
E L KHKL +E++L+ +E Q + Q+ + +NQ
Sbjct: 560 HERLLKHKLKVQEEMLK---------EEFQKKSEQLNKEINQ 592
>gi|118766328 transmembrane and tetratricopeptide repeat containing
4 isoform 2 [Homo sapiens]
Length = 741
Score = 40.0 bits (92), Expect = 0.013
Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 2/97 (2%)
Query: 633 GNSTFAIACLQRALNLAPLQYQDVPLVNLANLLIHYGLHLDATKLLLQALAINSSEPLTF 692
GN T AI + A+ L P + NL N+L +A +LL A+ I +
Sbjct: 496 GNQTAAIRYYREAVRLNPKYVH--AMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAW 553
Query: 693 LSLGNAYLALKNISGALEAFRQALKLTTKCPECENSL 729
++LG +LK A +++R A+K K P+C +L
Sbjct: 554 MNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNL 590
Score = 36.2 bits (82), Expect = 0.18
Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 2/86 (2%)
Query: 1028 KGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVN 1087
KG AI R+A+ P + + +L NIL +A + ++AV+I P FA
Sbjct: 495 KGNQTAAIRYYREAVRLNPKYVH--AMNNLGNILKERNELQEAEELLSLAVQIQPDFAAA 552
Query: 1088 HFTLGNVYVAMEEFEKALVWYESTLK 1113
LG V +++ FE A Y + +K
Sbjct: 553 WMNLGIVQNSLKRFEAAEQSYRTAIK 578
Score = 31.6 bits (70), Expect = 4.5
Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Query: 1039 RQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVYVAM 1098
R+AL P+ + SLAN+L ++ + ++ + A++ P+ A H L +Y
Sbjct: 642 REALELIPNDHS--LMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRW 699
Query: 1099 EEFEKALVWYESTLKLQP 1116
+ A YE +L+L P
Sbjct: 700 GHLDLAKKHYEISLQLDP 717
>gi|118766330 transmembrane and tetratricopeptide repeat containing
4 isoform 1 [Homo sapiens]
Length = 760
Score = 40.0 bits (92), Expect = 0.013
Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 2/97 (2%)
Query: 633 GNSTFAIACLQRALNLAPLQYQDVPLVNLANLLIHYGLHLDATKLLLQALAINSSEPLTF 692
GN T AI + A+ L P + NL N+L +A +LL A+ I +
Sbjct: 515 GNQTAAIRYYREAVRLNPKYVH--AMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAW 572
Query: 693 LSLGNAYLALKNISGALEAFRQALKLTTKCPECENSL 729
++LG +LK A +++R A+K K P+C +L
Sbjct: 573 MNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNL 609
Score = 36.2 bits (82), Expect = 0.18
Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 2/86 (2%)
Query: 1028 KGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVN 1087
KG AI R+A+ P + + +L NIL +A + ++AV+I P FA
Sbjct: 514 KGNQTAAIRYYREAVRLNPKYVH--AMNNLGNILKERNELQEAEELLSLAVQIQPDFAAA 571
Query: 1088 HFTLGNVYVAMEEFEKALVWYESTLK 1113
LG V +++ FE A Y + +K
Sbjct: 572 WMNLGIVQNSLKRFEAAEQSYRTAIK 597
Score = 31.6 bits (70), Expect = 4.5
Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Query: 1039 RQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVYVAM 1098
R+AL P+ + SLAN+L ++ + ++ + A++ P+ A H L +Y
Sbjct: 661 REALELIPNDHS--LMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRW 718
Query: 1099 EEFEKALVWYESTLKLQP 1116
+ A YE +L+L P
Sbjct: 719 GHLDLAKKHYEISLQLDP 736
>gi|148234215 guanylate binding protein 4-like [Homo sapiens]
Length = 638
Score = 39.7 bits (91), Expect = 0.017
Identities = 28/111 (25%), Positives = 60/111 (54%), Gaps = 5/111 (4%)
Query: 319 DHALQARPGFEQAIKRKHAVLCQQKLEQK--LEAQHRSLQRTLNEL-KEYQKQHDHYLRQ 375
+ A+ A+ ++A +++ +L Q++ EQ+ +EAQ RS Q + +L K+ +++ ++Y+R+
Sbjct: 485 EKAIAAKQAKKEAAEKEQELLRQKQKEQQQMMEAQERSFQENIAQLKKKMERERENYMRE 544
Query: 376 QEILEKHKLIQEEQILRNIIHE--TQMAKEAQLGNHQICRLVNQQHSLHCQ 424
+ HK+ E++L E + +E QI N++ S+ Q
Sbjct: 545 LRKMLSHKMKVLEELLTEGFKEIFESLNEEINRLKEQIEAAENEEPSVFSQ 595
>gi|118402596 cell division cycle protein 23 [Homo sapiens]
Length = 597
Score = 39.3 bits (90), Expect = 0.022
Identities = 24/111 (21%), Positives = 56/111 (50%), Gaps = 3/111 (2%)
Query: 1011 NQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDA 1070
+++S+++S +A Y ++ K A+ + P++++++ S N+L+ + ++
Sbjct: 260 SKSSYIVSQIAVAYHNIRDIDK-ALSIFNELRKQDPYRIENMDTFS--NLLYVRSMKSEL 316
Query: 1071 VIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPA 1121
+A EI + +GN Y + EKA ++++ LKL P ++ A
Sbjct: 317 SYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGA 367
>gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo
sapiens]
Length = 504
Score = 36.2 bits (82), Expect = 0.18
Identities = 28/94 (29%), Positives = 48/94 (51%), Gaps = 4/94 (4%)
Query: 279 ADAAVVVHAALD-DSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQARPGFEQA-IKRKH 336
ADA HAA+D D D + +YY ++ +G+ ++ +Q + F A ++R H
Sbjct: 54 ADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGH 113
Query: 337 AVLCQQKLEQKLEAQHRSLQR--TLNELKEYQKQ 368
+L Q KL++ + + L+ + NE KE Q Q
Sbjct: 114 LLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQ 147
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 36.2 bits (82), Expect = 0.18
Identities = 41/161 (25%), Positives = 66/161 (40%), Gaps = 16/161 (9%)
Query: 983 VLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKG-----QGK--KAI 1035
+L L KD +SL Q E + + S AL + KG QGK +AI
Sbjct: 101 ILDELDKDDSTHESLSQES-------ESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAI 153
Query: 1036 DCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVY 1095
DC + + P+ V + A+ K + A +AV + + + G
Sbjct: 154 DCYTKGMDADPYN--PVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAAR 211
Query: 1096 VAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKK 1136
A+++ E+A YE L+L+P A N ++ I L K+
Sbjct: 212 FALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKE 252
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 36.2 bits (82), Expect = 0.18
Identities = 41/161 (25%), Positives = 66/161 (40%), Gaps = 16/161 (9%)
Query: 983 VLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKG-----QGK--KAI 1035
+L L KD +SL Q E + + S AL + KG QGK +AI
Sbjct: 101 ILDELDKDDSTHESLSQES-------ESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAI 153
Query: 1036 DCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVY 1095
DC + + P+ V + A+ K + A +AV + + + G
Sbjct: 154 DCYTKGMDADPYN--PVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAAR 211
Query: 1096 VAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKK 1136
A+++ E+A YE L+L+P A N ++ I L K+
Sbjct: 212 FALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKE 252
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 36.2 bits (82), Expect = 0.18
Identities = 25/69 (36%), Positives = 37/69 (53%), Gaps = 6/69 (8%)
Query: 327 GFEQA--IKRKHAVLCQQ----KLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILE 380
GF+Q K KH +L ++ K+EQ+LEA+ R L RT EL + ++ E L+
Sbjct: 175 GFQQQELSKIKHMLLKKEESLGKMEQELEARTRELSRTQEELMNSNQMSSDLSQKLEELQ 234
Query: 381 KHKLIQEEQ 389
+H EEQ
Sbjct: 235 RHYSTLEEQ 243
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 35.8 bits (81), Expect = 0.24
Identities = 32/116 (27%), Positives = 55/116 (47%), Gaps = 10/116 (8%)
Query: 322 LQARPGFEQAIKRKHAVLCQQKLEQKL-EAQHRSLQRTLNELKEYQKQHDHYLRQQEILE 380
LQ + EQ + ++ L QQ EQ+L + Q LQ+ ++ Q Q + +QQE L+
Sbjct: 177 LQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQ 236
Query: 381 KHK----LIQEEQILRNIIHETQMAKEAQLGNHQICR-----LVNQQHSLHCQWDQ 427
+ + L Q+ Q+ + ++ + Q + QL Q + L+ QQ L Q Q
Sbjct: 237 QQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQ 292
Score = 34.7 bits (78), Expect = 0.53
Identities = 25/89 (28%), Positives = 45/89 (50%), Gaps = 5/89 (5%)
Query: 330 QAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQ 389
Q + KH + Q+L+ +L+ H+ Q +++E Q+ L+QQ+ + + QE+Q
Sbjct: 132 QLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQR-----LQQQQEQLQTQQAQEQQ 186
Query: 390 ILRNIIHETQMAKEAQLGNHQICRLVNQQ 418
+L+ Q +E QL Q +L QQ
Sbjct: 187 VLQQQEQLQQQVQEQQLLQQQQEQLQQQQ 215
Score = 33.5 bits (75), Expect = 1.2
Identities = 23/95 (24%), Positives = 49/95 (51%), Gaps = 3/95 (3%)
Query: 330 QAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQ 389
Q ++ + + QQ+ Q +AQ + + + +L++ ++ +QQE L++ +L+Q+++
Sbjct: 162 QQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQE 221
Query: 390 ILRNIIHETQMAKEAQLGNHQICRLVNQQHSLHCQ 424
L+ + Q + QL Q L+ QQ L Q
Sbjct: 222 QLQQQQFQQQ---QEQLQQQQQLLLLQQQGQLQQQ 253
Score = 31.2 bits (69), Expect = 5.9
Identities = 21/78 (26%), Positives = 38/78 (48%)
Query: 341 QQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQM 400
QQ+ EQ + Q L + +L++ Q QQ++LE+ + ++Q+L + Q
Sbjct: 229 QQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQ 288
Query: 401 AKEAQLGNHQICRLVNQQ 418
++ QL Q +L QQ
Sbjct: 289 QQQQQLLQQQQEQLQQQQ 306
>gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapiens]
Length = 830
Score = 35.4 bits (80), Expect = 0.31
Identities = 34/142 (23%), Positives = 60/142 (42%), Gaps = 8/142 (5%)
Query: 987 LGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAP 1046
LG Y Q+ K L+ N S VL + + +KA+D L +A+ P
Sbjct: 647 LGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDP 706
Query: 1047 HQMKDVPLISL--ANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKA 1104
PL A++L + + A+ +I P ++ +F +G VY + + A
Sbjct: 707 KN----PLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLA 762
Query: 1105 LVWYESTLKLQPEFVPAKNRIQ 1126
L+ + + L P+ A N+I+
Sbjct: 763 LMNFSWAMDLDPK--GANNQIK 782
Score = 33.1 bits (74), Expect = 1.5
Identities = 12/40 (30%), Positives = 26/40 (65%)
Query: 1077 AVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQP 1116
A+++ P++A + LG+ +V EE +KAL + + +++ P
Sbjct: 599 AIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNP 638
>gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapiens]
Length = 824
Score = 35.4 bits (80), Expect = 0.31
Identities = 34/142 (23%), Positives = 60/142 (42%), Gaps = 8/142 (5%)
Query: 987 LGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAP 1046
LG Y Q+ K L+ N S VL + + +KA+D L +A+ P
Sbjct: 641 LGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDP 700
Query: 1047 HQMKDVPLISL--ANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKA 1104
PL A++L + + A+ +I P ++ +F +G VY + + A
Sbjct: 701 KN----PLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLA 756
Query: 1105 LVWYESTLKLQPEFVPAKNRIQ 1126
L+ + + L P+ A N+I+
Sbjct: 757 LMNFSWAMDLDPK--GANNQIK 776
Score = 33.1 bits (74), Expect = 1.5
Identities = 12/40 (30%), Positives = 26/40 (65%)
Query: 1077 AVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQP 1116
A+++ P++A + LG+ +V EE +KAL + + +++ P
Sbjct: 593 AIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNP 632
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 35.4 bits (80), Expect = 0.31
Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 12/90 (13%)
Query: 330 QAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQ 389
QA R A+L +Q+ +Q+ + Q + Q+ + ++ Q+Q +++RQQ Q++Q
Sbjct: 2039 QAGVRSTAILPEQQQQQQQQQQQQQQQQ---QQQQQQQQQQYHIRQQ---------QQQQ 2086
Query: 390 ILRNIIHETQMAKEAQLGNHQICRLVNQQH 419
ILR + Q ++ Q Q + QQH
Sbjct: 2087 ILRQQQQQQQQQQQQQQQQQQQQQQQQQQH 2116
>gi|153085395 histone deacetylase 4 [Homo sapiens]
Length = 1084
Score = 35.0 bits (79), Expect = 0.41
Identities = 24/84 (28%), Positives = 52/84 (61%), Gaps = 5/84 (5%)
Query: 339 LCQQKLEQKLEA--QHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIH 396
L +Q+L+Q+L A Q + +QR + + E+Q+QH+ RQ E + H+ I+++Q + + H
Sbjct: 66 LREQQLQQELLALKQKQQIQRQIL-IAEFQRQHEQLSRQHE-AQLHEHIKQQQEMLAMKH 123
Query: 397 ETQMAK-EAQLGNHQICRLVNQQH 419
+ ++ + + +L H+ + + +QH
Sbjct: 124 QQELLEHQRKLERHRQEQELEKQH 147
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 34.7 bits (78), Expect = 0.53
Identities = 29/117 (24%), Positives = 56/117 (47%), Gaps = 9/117 (7%)
Query: 333 KRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQ-----QEILEKHKLIQE 387
+R+H + +L+ KL+ +LQ ++EL+ Q +HD L + QE + K ++E
Sbjct: 1350 EREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKMLQETVSKEAELRE 1409
Query: 388 EQILRNIIHETQMAKEAQLGNHQICRLVNQQHSLHCQWDQPVRYHRGDIFENVDYVQ 444
+ L +I E M K + +L +Q L + VR+ + + + V+ +Q
Sbjct: 1410 K--LCSIQSENMMMKSEH--TQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTVETLQ 1462
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 34.7 bits (78), Expect = 0.53
Identities = 32/118 (27%), Positives = 55/118 (46%), Gaps = 17/118 (14%)
Query: 332 IKRKHAVLCQ--QKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQ 389
+++KHA+L + L+QKLE + QR L E + Q+Q D L++ I + +QE
Sbjct: 1124 LEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMD--LQKNHIFRLTQGLQEAL 1181
Query: 390 ILRNIIHETQMAKEAQLGNHQIC---------RLVNQQHS----LHCQWDQPVRYHRG 434
+++ + E QL N Q+ ++QQ L + DQP + +G
Sbjct: 1182 DRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTKLIDFLQAKMDQPAKKKKG 1239
>gi|60685231 tetratricopeptide repeat domain 7B [Homo sapiens]
Length = 843
Score = 34.7 bits (78), Expect = 0.53
Identities = 36/140 (25%), Positives = 52/140 (37%), Gaps = 35/140 (25%)
Query: 616 APIWLILNEAGLYWRAVGNSTFAIACLQRALNLAPLQ----------------------- 652
A IWL A + +G A AC Q A NL P+
Sbjct: 696 AQIWL---HAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQIAELRGSMDEARRW 752
Query: 653 YQDVPLVN---------LANLLIHYGLHLDATKLLLQALAINSSEPLTFLSLGNAYLALK 703
Y++ ++ LA +L G + A K+L A+ +NS+ + LG A
Sbjct: 753 YEEALAISPTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQG 812
Query: 704 NISGALEAFRQALKLTTKCP 723
N + A E F AL+L P
Sbjct: 813 NDAAATECFLTALELEASSP 832
>gi|157502225 Janus kinase and microtubule interacting protein 3
[Homo sapiens]
Length = 844
Score = 34.3 bits (77), Expect = 0.69
Identities = 25/106 (23%), Positives = 49/106 (46%), Gaps = 11/106 (10%)
Query: 298 YYTLGNIYAMLGEYNHSVLCYDHALQARPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQR 357
Y L YA+L E L + ++ R + ++R A ++E ++L
Sbjct: 509 YQALQRAYALLQEQVGGTLDAEREVKTREQLQAEVQRAQA---------RIEDLEKALAE 559
Query: 358 TLNELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKE 403
++K +++ Y R QE++EK K ++ E+ + HE Q A++
Sbjct: 560 QGQDMKWIEEKQALYRRNQELVEKIKQMETEE--ARLRHEVQDARD 603
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 34.3 bits (77), Expect = 0.69
Identities = 28/75 (37%), Positives = 40/75 (53%), Gaps = 8/75 (10%)
Query: 333 KRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEI---LEKHKLI--QE 387
KR+ A+L QQ+ EQ+ AQ L+R E KE ++Q RQ E+ LEK + + Q
Sbjct: 367 KRRQALLEQQRKEQERLAQ---LERAEQERKERERQEQERKRQLELEKQLEKQRELERQR 423
Query: 388 EQILRNIIHETQMAK 402
E+ R I + AK
Sbjct: 424 EEERRKEIERREAAK 438
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 34.3 bits (77), Expect = 0.69
Identities = 28/75 (37%), Positives = 40/75 (53%), Gaps = 8/75 (10%)
Query: 333 KRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEI---LEKHKLI--QE 387
KR+ A+L QQ+ EQ+ AQ L+R E KE ++Q RQ E+ LEK + + Q
Sbjct: 367 KRRQALLEQQRKEQERLAQ---LERAEQERKERERQEQERKRQLELEKQLEKQRELERQR 423
Query: 388 EQILRNIIHETQMAK 402
E+ R I + AK
Sbjct: 424 EEERRKEIERREAAK 438
>gi|109255239 centrosomal protein 63 isoform b [Homo sapiens]
Length = 541
Score = 34.3 bits (77), Expect = 0.69
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 16/135 (11%)
Query: 332 IKRKHAVLCQQKLE-QKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEIL------EKHKL 384
++R + +C +LE ++L + L T + + Q+Q + LR+ E L EK +L
Sbjct: 213 LERANDTICANELEIERLTMRVNDLVGTSMTVLQEQQQKEEKLRESEKLLEALQEEKREL 272
Query: 385 IQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHSLHCQWDQPVRYHRGDIFENVDYVQ 444
Q N+IHE ++ KE + + N QH++ + +R + E Y
Sbjct: 273 KAALQSQENLIHEARIQKEKL---QEKVKATNTQHAV-----EAIRPREESLAEK-KYTS 323
Query: 445 FGEDSSTSSMMSVNF 459
G+ S + +NF
Sbjct: 324 QGQGDLDSVLSQLNF 338
>gi|22095367 centrosomal protein 63 isoform a [Homo sapiens]
Length = 703
Score = 34.3 bits (77), Expect = 0.69
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 16/135 (11%)
Query: 332 IKRKHAVLCQQKLE-QKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEIL------EKHKL 384
++R + +C +LE ++L + L T + + Q+Q + LR+ E L EK +L
Sbjct: 213 LERANDTICANELEIERLTMRVNDLVGTSMTVLQEQQQKEEKLRESEKLLEALQEEKREL 272
Query: 385 IQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHSLHCQWDQPVRYHRGDIFENVDYVQ 444
Q N+IHE ++ KE + + N QH++ + +R + E Y
Sbjct: 273 KAALQSQENLIHEARIQKEKL---QEKVKATNTQHAV-----EAIRPREESLAEK-KYTS 323
Query: 445 FGEDSSTSSMMSVNF 459
G+ S + +NF
Sbjct: 324 QGQGDLDSVLSQLNF 338
>gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo
sapiens]
Length = 1719
Score = 34.3 bits (77), Expect = 0.69
Identities = 34/119 (28%), Positives = 55/119 (46%), Gaps = 6/119 (5%)
Query: 329 EQAIKRKHAVLCQQKLEQKLE---AQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLI 385
E+ K + V LEQ+LE A + L ++K Y+KQ +++E L K +L+
Sbjct: 494 EEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNK-ELV 552
Query: 386 QEEQILRNIIHETQMAK-EAQLGNHQICRLVNQQHSLHCQWDQPVRYHRGDIFENVDYV 443
Q + L+N E + A + +L + + + LH Q Q + H D E VD V
Sbjct: 553 QASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQ-KQKLARHVRDKEEEVDLV 610
>gi|156231067 TBC1 domain family, member 8 [Homo sapiens]
Length = 1140
Score = 33.9 bits (76), Expect = 0.91
Identities = 16/63 (25%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 366 QKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHSLHCQW 425
Q +H Y + +L+ H+ ++ +LR +I E + E ++ L ++H + C W
Sbjct: 778 QIEHLRYKHRIRVLQGHEDTTKQNVLRVVIPEVSILPEDL---EELYDLFKREHMMSCYW 834
Query: 426 DQP 428
+QP
Sbjct: 835 EQP 837
>gi|21735550 mitogen-activated protein kinase kinase kinase 10 [Homo
sapiens]
Length = 954
Score = 33.9 bits (76), Expect = 0.91
Identities = 36/148 (24%), Positives = 61/148 (41%), Gaps = 16/148 (10%)
Query: 317 CYDHALQARPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQ 376
C+D RP F +KR + + LE+ H SLQ ++++ + H
Sbjct: 339 CWDPDPHGRPDFGSILKRLEVIEQSALFQMPLESFH-SLQ------EDWKLEIQHMFDDL 391
Query: 377 EILEKHKLIQEEQILR-----NIIHETQMAKEAQLGNHQICRLVNQQHSLHCQWDQP--- 428
EK +EE++LR E +E +L ++ + + H L CQ Q
Sbjct: 392 RTKEKELRSREEELLRAAQEQRFQEEQLRRREQELAEREMDIVERELHLLMCQLSQEKPR 451
Query: 429 VRYHRGDIFENVDYVQFGEDSSTSSMMS 456
VR +G+ F+ ++ E S S+ S
Sbjct: 452 VRKRKGN-FKRSRLLKLREGGSHISLPS 478
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,328,949
Number of Sequences: 37866
Number of extensions: 2049880
Number of successful extensions: 8017
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 71
Number of HSP's that attempted gapping in prelim test: 7498
Number of HSP's gapped (non-prelim): 475
length of query: 1141
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1028
effective length of database: 13,968,660
effective search space: 14359782480
effective search space used: 14359782480
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.