Guide to the Human Genome
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Search of human proteins with 21361625

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21361625 Sec5 protein [Homo sapiens]
         (924 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21361625 Sec5 protein [Homo sapiens]                              1839   0.0  
gi|194272180 plexin B1 [Homo sapiens]                                  43   0.001
gi|40254442 plexin B1 [Homo sapiens]                                   43   0.001
gi|149363636 plexin B2 [Homo sapiens]                                  42   0.003
gi|157738645 plexin A4 isoform 1 [Homo sapiens]                        39   0.017
gi|59710104 plexin A3 [Homo sapiens]                                   37   0.065
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]           35   0.42 
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]          35   0.42 
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]          35   0.42 
gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]           35   0.42 
gi|23503243 Ras association (RalGDS/AF-6) domain family (N-termi...    35   0.42 
gi|64762445 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase ...    33   1.2  
gi|64762406 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase ...    33   1.2  
gi|8393009 chromosome 11 open reading frame2 [Homo sapiens]            33   1.6  
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...    32   2.1  
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof...    32   2.1  
gi|4505541 USO1 homolog, vesicle docking protein [Homo sapiens]        32   3.6  
gi|7705720 mediator of cell motility 1 isoform 1 [Homo sapiens]        31   4.7  
gi|212286159 mediator of cell motility 1 isoform 2 [Homo sapiens]      31   4.7  
gi|126116589 fibrocystin L [Homo sapiens]                              31   4.7  
gi|229331967 RIO kinase 2 isoform 1 [Homo sapiens]                     31   6.1  
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]          31   6.1  
gi|120587023 down-regulated in metastasis [Homo sapiens]               30   7.9  
gi|89036565 PREDICTED: similar to Temporarily Assigned Gene name...    30   7.9  
gi|24430181 outer dense fiber of sperm tails 2 isoform 1 [Homo s...    30   7.9  
gi|7661880 centaurin beta1 [Homo sapiens]                              30   7.9  
gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens]               30   7.9  

>gi|21361625 Sec5 protein [Homo sapiens]
          Length = 924

 Score = 1839 bits (4764), Expect = 0.0
 Identities = 924/924 (100%), Positives = 924/924 (100%)

Query: 1   MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKI 60
           MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKI
Sbjct: 1   MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKI 60

Query: 61  VCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDR 120
           VCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDR
Sbjct: 61  VCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDR 120

Query: 121 NKGIPPLSLRPANPLGIEIEKSKFSQKDLEMLFHGMSADFTSENFSAAWYLIENHSNTSF 180
           NKGIPPLSLRPANPLGIEIEKSKFSQKDLEMLFHGMSADFTSENFSAAWYLIENHSNTSF
Sbjct: 121 NKGIPPLSLRPANPLGIEIEKSKFSQKDLEMLFHGMSADFTSENFSAAWYLIENHSNTSF 180

Query: 181 EQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQ 240
           EQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQ
Sbjct: 181 EQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQ 240

Query: 241 KLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYD 300
           KLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYD
Sbjct: 241 KLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYD 300

Query: 301 VVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYL 360
           VVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYL
Sbjct: 301 VVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYL 360

Query: 361 SDLHASGDPAWQCIGAQHKWILQLMHSCKEGYVKDLKGNPGLHSPMLDLDNDTRPSVLGH 420
           SDLHASGDPAWQCIGAQHKWILQLMHSCKEGYVKDLKGNPGLHSPMLDLDNDTRPSVLGH
Sbjct: 361 SDLHASGDPAWQCIGAQHKWILQLMHSCKEGYVKDLKGNPGLHSPMLDLDNDTRPSVLGH 420

Query: 421 LSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFS 480
           LSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFS
Sbjct: 421 LSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFS 480

Query: 481 ETAEKSGQIERSKNVRQRQNDFKKMIQEVMHSLVKLTRGALLPLSIRDGEAKQYGGWEVK 540
           ETAEKSGQIERSKNVRQRQNDFKKMIQEVMHSLVKLTRGALLPLSIRDGEAKQYGGWEVK
Sbjct: 481 ETAEKSGQIERSKNVRQRQNDFKKMIQEVMHSLVKLTRGALLPLSIRDGEAKQYGGWEVK 540

Query: 541 CELSGQWLAHAIQTVRLTHESLTALEIPNDLLQTIQDLILDLRVRCVMATLQHTAEEIKR 600
           CELSGQWLAHAIQTVRLTHESLTALEIPNDLLQTIQDLILDLRVRCVMATLQHTAEEIKR
Sbjct: 541 CELSGQWLAHAIQTVRLTHESLTALEIPNDLLQTIQDLILDLRVRCVMATLQHTAEEIKR 600

Query: 601 LAEKEDWIVDNEGLTSLPCQFEQCIVCSLQSLKGVLECKPGEASVFQQPKTQEEVCQLSI 660
           LAEKEDWIVDNEGLTSLPCQFEQCIVCSLQSLKGVLECKPGEASVFQQPKTQEEVCQLSI
Sbjct: 601 LAEKEDWIVDNEGLTSLPCQFEQCIVCSLQSLKGVLECKPGEASVFQQPKTQEEVCQLSI 660

Query: 661 NIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCY 720
           NIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCY
Sbjct: 661 NIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCY 720

Query: 721 LERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLEPGIY 780
           LERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLEPGIY
Sbjct: 721 LERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLEPGIY 780

Query: 781 AGYFDWKDCLPPTGVRNYLKEALVNIIAVHAEVFTISKELVPRVLSKVIEAVSEELSRLM 840
           AGYFDWKDCLPPTGVRNYLKEALVNIIAVHAEVFTISKELVPRVLSKVIEAVSEELSRLM
Sbjct: 781 AGYFDWKDCLPPTGVRNYLKEALVNIIAVHAEVFTISKELVPRVLSKVIEAVSEELSRLM 840

Query: 841 QCVSSFSKNGALQARLEICALRDTVAVYLTPESKSSFKQALEALPQLSSGADKKLLEELL 900
           QCVSSFSKNGALQARLEICALRDTVAVYLTPESKSSFKQALEALPQLSSGADKKLLEELL
Sbjct: 841 QCVSSFSKNGALQARLEICALRDTVAVYLTPESKSSFKQALEALPQLSSGADKKLLEELL 900

Query: 901 NKFKSSMHLQLTCFQAASSTMMKT 924
           NKFKSSMHLQLTCFQAASSTMMKT
Sbjct: 901 NKFKSSMHLQLTCFQAASSTMMKT 924


>gi|194272180 plexin B1 [Homo sapiens]
          Length = 2135

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 5/94 (5%)

Query: 8    PLVTGISPNEGIP--WTKVTIRGENLGTGPTDLIGL-TICGHNCLLTA-EWMSASKIVCR 63
            PL+  + P  G     T+VTIRG NLG    D++G+ T+ G  C + A E+  +S +VC 
Sbjct: 1070 PLIHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCI 1129

Query: 64   VGQAKND-KGDIIVTTKSGGRGTSTVSFKLLKPE 96
             G +  +  G   V     GRG S   F    P+
Sbjct: 1130 TGASGEEVAGATAVEVPGRGRGVSEHDFAYQDPK 1163


>gi|40254442 plexin B1 [Homo sapiens]
          Length = 2135

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 5/94 (5%)

Query: 8    PLVTGISPNEGIP--WTKVTIRGENLGTGPTDLIGL-TICGHNCLLTA-EWMSASKIVCR 63
            PL+  + P  G     T+VTIRG NLG    D++G+ T+ G  C + A E+  +S +VC 
Sbjct: 1070 PLIHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCI 1129

Query: 64   VGQAKND-KGDIIVTTKSGGRGTSTVSFKLLKPE 96
             G +  +  G   V     GRG S   F    P+
Sbjct: 1130 TGASGEEVAGATAVEVPGRGRGVSEHDFAYQDPK 1163


>gi|149363636 plexin B2 [Homo sapiens]
          Length = 1838

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 5/102 (4%)

Query: 7   PPLVTGISPNEGI--PWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSAS-KIVCR 63
           PP++T I P  G      ++TI G NLG    D+  +++ G NC    E  S S +IVC 
Sbjct: 802 PPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISVAGRNCSFQPERYSVSTRIVCV 861

Query: 64  VGQAKNDKGDIIVTTKSG--GRGTSTVSFKLLKPEKIGILDQ 103
           +  A+      +     G  GR    V F   +P+ + +  Q
Sbjct: 862 IEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSVEPQ 903


>gi|157738645 plexin A4 isoform 1 [Homo sapiens]
          Length = 1894

 Score = 39.3 bits (90), Expect = 0.017
 Identities = 28/61 (45%), Positives = 36/61 (59%), Gaps = 6/61 (9%)

Query: 10  VTGISPNEGIPWTKVTIRGENLGTGPTDLIG-LTICGHNCL-LTAEWMSASKIVCRVGQA 67
           VTG  P EG   TKVTIRGENLG    D+   + + G  C  L   ++ A +IVC +G+A
Sbjct: 866 VTG--PREG--GTKVTIRGENLGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEA 921

Query: 68  K 68
           K
Sbjct: 922 K 922


>gi|59710104 plexin A3 [Homo sapiens]
          Length = 1871

 Score = 37.4 bits (85), Expect = 0.065
 Identities = 22/56 (39%), Positives = 35/56 (62%), Gaps = 4/56 (7%)

Query: 13  ISPNEGIPWTKVTIRGENLGTGPTDLIGLTICGHNC-LLTAEWMSASKIVCRVGQA 67
           + P EG   T+VTI G+NLG    + +GL + G  C  + AE++SA +IVC + ++
Sbjct: 849 VGPKEG--GTRVTIVGDNLGLLSRE-VGLRVAGVRCNSIPAEYISAERIVCEMEES 901


>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
          Length = 3333

 Score = 34.7 bits (78), Expect = 0.42
 Identities = 47/212 (22%), Positives = 86/212 (40%), Gaps = 49/212 (23%)

Query: 173  ENHSNTSFEQLKMAVTNLKRQANKKS------EGSLAYVKGGLSTFFEAQDAL------- 219
            E H+  S ++L   +  +KR A+         + + AY +  L+    A+DA        
Sbjct: 2143 EKHAR-SLQELAKQLEEIKRNASGDELVRCAVDAATAY-ENILNAIKAAEDAANRAASAS 2200

Query: 220  -SAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQ 278
             SA+   ++ D   K + +++   + +LN A  T   L QEV       ++ +  LN++ 
Sbjct: 2201 ESALQTVIKEDLPRKAK-TLSSNSDKLLNEAKMTQKKLKQEV---SPALNNLQQTLNIVT 2256

Query: 279  RFKFLFNLPLNIERN----IQKGDYDVVIN-------------------------DYEKA 309
              K + +  L   R+    IQ+GD D +I+                         D E+ 
Sbjct: 2257 VQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERI 2316

Query: 310  KSLFGKTEVQVFKKYYAEVETRIEALRELLLD 341
            K  +G+T+ + FKK   + +  +  L   L D
Sbjct: 2317 KDTYGRTQNEDFKKALTDADNSVNKLTNKLPD 2348


>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
          Length = 1668

 Score = 34.7 bits (78), Expect = 0.42
 Identities = 47/212 (22%), Positives = 86/212 (40%), Gaps = 49/212 (23%)

Query: 173 ENHSNTSFEQLKMAVTNLKRQANKKS------EGSLAYVKGGLSTFFEAQDAL------- 219
           E H+  S ++L   +  +KR A+         + + AY +  L+    A+DA        
Sbjct: 478 EKHAR-SLQELAKQLEEIKRNASGDELVRCAVDAATAY-ENILNAIKAAEDAANRAASAS 535

Query: 220 -SAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQ 278
            SA+   ++ D   K + +++   + +LN A  T   L QEV       ++ +  LN++ 
Sbjct: 536 ESALQTVIKEDLPRKAK-TLSSNSDKLLNEAKMTQKKLKQEV---SPALNNLQQTLNIVT 591

Query: 279 RFKFLFNLPLNIERN----IQKGDYDVVIN-------------------------DYEKA 309
             K + +  L   R+    IQ+GD D +I+                         D E+ 
Sbjct: 592 VQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERI 651

Query: 310 KSLFGKTEVQVFKKYYAEVETRIEALRELLLD 341
           K  +G+T+ + FKK   + +  +  L   L D
Sbjct: 652 KDTYGRTQNEDFKKALTDADNSVNKLTNKLPD 683


>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
          Length = 3277

 Score = 34.7 bits (78), Expect = 0.42
 Identities = 47/212 (22%), Positives = 86/212 (40%), Gaps = 49/212 (23%)

Query: 173  ENHSNTSFEQLKMAVTNLKRQANKKS------EGSLAYVKGGLSTFFEAQDAL------- 219
            E H+  S ++L   +  +KR A+         + + AY +  L+    A+DA        
Sbjct: 2087 EKHAR-SLQELAKQLEEIKRNASGDELVRCAVDAATAY-ENILNAIKAAEDAANRAASAS 2144

Query: 220  -SAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQ 278
             SA+   ++ D   K + +++   + +LN A  T   L QEV       ++ +  LN++ 
Sbjct: 2145 ESALQTVIKEDLPRKAK-TLSSNSDKLLNEAKMTQKKLKQEV---SPALNNLQQTLNIVT 2200

Query: 279  RFKFLFNLPLNIERN----IQKGDYDVVIN-------------------------DYEKA 309
              K + +  L   R+    IQ+GD D +I+                         D E+ 
Sbjct: 2201 VQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERI 2260

Query: 310  KSLFGKTEVQVFKKYYAEVETRIEALRELLLD 341
            K  +G+T+ + FKK   + +  +  L   L D
Sbjct: 2261 KDTYGRTQNEDFKKALTDADNSVNKLTNKLPD 2292


>gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
          Length = 1724

 Score = 34.7 bits (78), Expect = 0.42
 Identities = 47/212 (22%), Positives = 86/212 (40%), Gaps = 49/212 (23%)

Query: 173 ENHSNTSFEQLKMAVTNLKRQANKKS------EGSLAYVKGGLSTFFEAQDAL------- 219
           E H+  S ++L   +  +KR A+         + + AY +  L+    A+DA        
Sbjct: 534 EKHAR-SLQELAKQLEEIKRNASGDELVRCAVDAATAY-ENILNAIKAAEDAANRAASAS 591

Query: 220 -SAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQ 278
            SA+   ++ D   K + +++   + +LN A  T   L QEV       ++ +  LN++ 
Sbjct: 592 ESALQTVIKEDLPRKAK-TLSSNSDKLLNEAKMTQKKLKQEV---SPALNNLQQTLNIVT 647

Query: 279 RFKFLFNLPLNIERN----IQKGDYDVVIN-------------------------DYEKA 309
             K + +  L   R+    IQ+GD D +I+                         D E+ 
Sbjct: 648 VQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERI 707

Query: 310 KSLFGKTEVQVFKKYYAEVETRIEALRELLLD 341
           K  +G+T+ + FKK   + +  +  L   L D
Sbjct: 708 KDTYGRTQNEDFKKALTDADNSVNKLTNKLPD 739


>gi|23503243 Ras association (RalGDS/AF-6) domain family
           (N-terminal) member 8 [Homo sapiens]
          Length = 392

 Score = 34.7 bits (78), Expect = 0.42
 Identities = 29/126 (23%), Positives = 59/126 (46%), Gaps = 6/126 (4%)

Query: 235 EGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNAL--NVLQRFKFLFNLPLNIER 292
           +G  T+  + VLN    TAD L + +  + +K  S    L  N ++   +      N+E 
Sbjct: 145 KGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEE 204

Query: 293 NIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHD 352
            I + +  +  ND E  +  F + E+Q+ ++   +++ +++ +R+    K+ E  + L D
Sbjct: 205 EIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQ----KITECENKLKD 260

Query: 353 QKRYIR 358
               IR
Sbjct: 261 YLAQIR 266


>gi|64762445 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
           isoform b [Homo sapiens]
          Length = 471

 Score = 33.1 bits (74), Expect = 1.2
 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 4/76 (5%)

Query: 622 EQCIVCSLQSLKGVLECKPGEASVFQQPKTQEEVCQLSINIMQ---VFIYCLEQLSTKPD 678
           +QC + +L+ +K  L  + G+ +VF    T  E   + +N  +     ++ +E +   PD
Sbjct: 103 KQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDDPD 162

Query: 679 ADIDTTHLSVDVSSPD 694
             I    L V VSSPD
Sbjct: 163 V-IAANILEVKVSSPD 177


>gi|64762406 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
           isoform a [Homo sapiens]
          Length = 505

 Score = 33.1 bits (74), Expect = 1.2
 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 4/76 (5%)

Query: 622 EQCIVCSLQSLKGVLECKPGEASVFQQPKTQEEVCQLSINIMQ---VFIYCLEQLSTKPD 678
           +QC + +L+ +K  L  + G+ +VF    T  E   + +N  +     ++ +E +   PD
Sbjct: 103 KQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDDPD 162

Query: 679 ADIDTTHLSVDVSSPD 694
             I    L V VSSPD
Sbjct: 163 V-IAANILEVKVSSPD 177


>gi|8393009 chromosome 11 open reading frame2 [Homo sapiens]
          Length = 782

 Score = 32.7 bits (73), Expect = 1.6
 Identities = 43/215 (20%), Positives = 83/215 (38%), Gaps = 14/215 (6%)

Query: 159 DFTSENFSAAWYLIENHSNTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDA 218
           D    +F    YL +        QL  + T++ RQ           V    + F  A D 
Sbjct: 62  DLNGAHFDPEVYLDKLRRECPLAQLMDSETDMVRQIRALDSDMQTLVYENYNKFISATDT 121

Query: 219 LSAIHQKLEADGTEKVEGSMTQKLEN--VLNRASNTADTLFQEVLGRKDKADSTRNALNV 276
           +    +K++ D   K+E  M +   N  V+   S       Q+   R ++         +
Sbjct: 122 I----RKMKND-FRKMEDEMDRLATNMAVITDFSARISATLQD---RHERITKLAGVHAL 173

Query: 277 LQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTE-VQVFKKYYAEVETRIEAL 335
           L++ +FLF LP  + + ++ G Y   +    +A+++  + + +  F+    + +     L
Sbjct: 174 LRKLQFLFELPSRLTKCVELGAYGQAVRYQGRAQAVLQQYQHLPSFRAIQDDCQVITARL 233

Query: 336 RELLLDKLLETPSTLHDQKRYIRYLSDLHASGDPA 370
            + L  +  E  S   +Q   +  L    A G+PA
Sbjct: 234 AQQLRQRFREGGSGAPEQAECVELLL---ALGEPA 265


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
            [Homo sapiens]
          Length = 6907

 Score = 32.3 bits (72), Expect = 2.1
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 5/103 (4%)

Query: 818  KELVPRVLSKVIEAVSEELSRLMQCVSSFSKNGALQARLEICALRDTVAVYLTPESKSSF 877
            +E +P +      A +EELS L+ C+  + +N   Q  L    L+   ++   PES    
Sbjct: 3489 QEELPEISKTKEAATTEELSELLDCLCQYGENVEKQQLLLTLLLQRIRSIQNVPESSG-- 3546

Query: 878  KQALEALPQLSS-GADKKLLEELLNKFKSSMHLQLTCFQAASS 919
              A+E +P      + K+   +LL K + +  L  T  Q   S
Sbjct: 3547 --AVETVPAFQEITSMKERCNKLLQKVQKNKELVQTEIQERHS 3587


>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
            [Homo sapiens]
          Length = 6885

 Score = 32.3 bits (72), Expect = 2.1
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 5/103 (4%)

Query: 818  KELVPRVLSKVIEAVSEELSRLMQCVSSFSKNGALQARLEICALRDTVAVYLTPESKSSF 877
            +E +P +      A +EELS L+ C+  + +N   Q  L    L+   ++   PES    
Sbjct: 3489 QEELPEISKTKEAATTEELSELLDCLCQYGENVEKQQLLLTLLLQRIRSIQNVPESSG-- 3546

Query: 878  KQALEALPQLSS-GADKKLLEELLNKFKSSMHLQLTCFQAASS 919
              A+E +P      + K+   +LL K + +  L  T  Q   S
Sbjct: 3547 --AVETVPAFQEITSMKERCNKLLQKVQKNKELVQTEIQERHS 3587


>gi|4505541 USO1 homolog, vesicle docking protein [Homo sapiens]
          Length = 962

 Score = 31.6 bits (70), Expect = 3.6
 Identities = 41/183 (22%), Positives = 73/183 (39%), Gaps = 8/183 (4%)

Query: 138 EIEKSKFSQKDLEMLFHGMSADFTSENFSAAWYLIENHSNTSFEQLKMAVTNLKRQANKK 197
           E+ +S+ ++KD   +   M +  TS     +  ++    +    +LK  +  LK Q N +
Sbjct: 747 ELLQSQLTEKD--SMIENMKSSQTSGTNEQSSAIVSARDSEQVAELKQELATLKSQLNSQ 804

Query: 198 SEG--SLAYVKGGLSTFFEAQDALSAIHQKLE---ADGTEKVEGSMTQKLENVLNRASNT 252
           S     L   K  L    EA      +  + E   A  T  VEG ++  L+       N 
Sbjct: 805 SVEITKLQTEKQELLQKTEAFAKSVEVQGETETIIATKTTDVEGRLSALLQET-KELKNE 863

Query: 253 ADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSL 312
              L +E    K++ DS+ + + +LQ  K    L +   +  Q     ++ +  +K  SL
Sbjct: 864 IKALSEERTAIKEQLDSSNSTIAILQTEKDKLELEITDSKKEQDDLLVLLADQDQKILSL 923

Query: 313 FGK 315
             K
Sbjct: 924 KNK 926


>gi|7705720 mediator of cell motility 1 isoform 1 [Homo sapiens]
          Length = 297

 Score = 31.2 bits (69), Expect = 4.7
 Identities = 18/84 (21%), Positives = 40/84 (47%), Gaps = 1/84 (1%)

Query: 696 FGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKEL 755
           FG +   + L     L +V S+ C+  +    +  +  +   ++ IE + ++ M+ +++L
Sbjct: 169 FGKLFSKY-LADPSNLFVVSSDFCHWGQRFRYSYYDESQGEIYRSIEHLDKMGMSIIEQL 227

Query: 756 DQRLFENYIELKADPIVGSLEPGI 779
           D   F NY++   + I G    G+
Sbjct: 228 DPVSFSNYLKKYHNTICGRHPIGV 251


>gi|212286159 mediator of cell motility 1 isoform 2 [Homo sapiens]
          Length = 274

 Score = 31.2 bits (69), Expect = 4.7
 Identities = 18/84 (21%), Positives = 40/84 (47%), Gaps = 1/84 (1%)

Query: 696 FGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKEL 755
           FG +   + L     L +V S+ C+  +    +  +  +   ++ IE + ++ M+ +++L
Sbjct: 146 FGKLFSKY-LADPSNLFVVSSDFCHWGQRFRYSYYDESQGEIYRSIEHLDKMGMSIIEQL 204

Query: 756 DQRLFENYIELKADPIVGSLEPGI 779
           D   F NY++   + I G    G+
Sbjct: 205 DPVSFSNYLKKYHNTICGRHPIGV 228


>gi|126116589 fibrocystin L [Homo sapiens]
          Length = 4243

 Score = 31.2 bits (69), Expect = 4.7
 Identities = 15/31 (48%), Positives = 18/31 (58%)

Query: 8    PLVTGISPNEGIPWTKVTIRGENLGTGPTDL 38
            P +TG+ PN  I   KV I GE LGT   D+
Sbjct: 1749 PYITGVFPNSVIGSVKVLIEGEGLGTVLEDI 1779


>gi|229331967 RIO kinase 2 isoform 1 [Homo sapiens]
          Length = 552

 Score = 30.8 bits (68), Expect = 6.1
 Identities = 25/113 (22%), Positives = 51/113 (45%), Gaps = 4/113 (3%)

Query: 171 LIENHSNTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADG 230
           ++EN+S T F + K    N  RQ  ++ +G +               ALS+++++     
Sbjct: 407 VVENNSVTEFSEEKNRTENYNRQDGQRVQGGVPAGSDEYEDECPHLIALSSLNREFRPFR 466

Query: 231 TEKVEGSMTQKLENVLNRASN----TADTLFQEVLGRKDKADSTRNALNVLQR 279
            E+  G+M Q     L+  S+    +  T+  E++ +K K   T+   + ++R
Sbjct: 467 DEENVGAMNQYRTRTLSITSSGSAVSCSTIPPELVKQKVKRQLTKQQKSAVRR 519


>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
          Length = 4646

 Score = 30.8 bits (68), Expect = 6.1
 Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 17/91 (18%)

Query: 489  IERSKNVRQRQNDFKKMIQEVMHSLVKLTRGALLPLSIRDGEAKQYGGWEVKCELS---- 544
            I  SKNV + Q  FKKM   V   ++      +L +S R+GE   +     K  +S    
Sbjct: 1641 IGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMF-----KTPVSITEH 1695

Query: 545  ---GQWLAHAIQTVRLT-----HESLTALEI 567
                +WL    + +R+T      ES+T +EI
Sbjct: 1696 PKINEWLTLVEKEMRVTLAKLLAESVTEVEI 1726


>gi|120587023 down-regulated in metastasis [Homo sapiens]
          Length = 2785

 Score = 30.4 bits (67), Expect = 7.9
 Identities = 31/143 (21%), Positives = 59/143 (41%), Gaps = 16/143 (11%)

Query: 490 ERSKNVRQRQNDFKKMIQEVMHSL----VKLTRGALLPLSIRDGEAKQYGGWEVKCELSG 545
           E+ + V Q   +  K ++ + HS     VKL    L P++            E + +L  
Sbjct: 219 EKVEGVGQLLFEMCKGVRNMFHSCTGQAVKLILRKLGPVT------------ETETQLPW 266

Query: 546 QWLAHAIQTVRLTHESLTALEIPNDLLQTIQDLILDLRVRCVMATLQHTAEEIKRLAEKE 605
             +   ++ +  +  S  + E      + +Q+ +LDL  +        ++E+IKRL E  
Sbjct: 267 MLIGETLKNMVKSTVSYISKEHFGTFFECLQESLLDLHTKVTKTNCCESSEQIKRLLETY 326

Query: 606 DWIVDNEGLTSLPCQFEQCIVCS 628
             +V +   T +P   + C V S
Sbjct: 327 LILVKHGSGTKIPTPADVCKVLS 349


>gi|89036565 PREDICTED: similar to Temporarily Assigned Gene name
           family member (tag-184) [Homo sapiens]
          Length = 2785

 Score = 30.4 bits (67), Expect = 7.9
 Identities = 31/143 (21%), Positives = 59/143 (41%), Gaps = 16/143 (11%)

Query: 490 ERSKNVRQRQNDFKKMIQEVMHSL----VKLTRGALLPLSIRDGEAKQYGGWEVKCELSG 545
           E+ + V Q   +  K ++ + HS     VKL    L P++            E + +L  
Sbjct: 219 EKVEGVGQLLFEMCKGVRNMFHSCTGQAVKLILRKLGPVT------------ETETQLPW 266

Query: 546 QWLAHAIQTVRLTHESLTALEIPNDLLQTIQDLILDLRVRCVMATLQHTAEEIKRLAEKE 605
             +   ++ +  +  S  + E      + +Q+ +LDL  +        ++E+IKRL E  
Sbjct: 267 MLIGETLKNMVKSTVSYISKEHFGTFFECLQESLLDLHTKVTKTNCCESSEQIKRLLETY 326

Query: 606 DWIVDNEGLTSLPCQFEQCIVCS 628
             +V +   T +P   + C V S
Sbjct: 327 LILVKHGSGTKIPTPADVCKVLS 349


>gi|24430181 outer dense fiber of sperm tails 2 isoform 1 [Homo
           sapiens]
          Length = 805

 Score = 30.4 bits (67), Expect = 7.9
 Identities = 34/183 (18%), Positives = 73/183 (39%), Gaps = 20/183 (10%)

Query: 184 KMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLE 243
           K+ +   K QA++K    L+     L    EA  A +    ++ A   E +  S   +LE
Sbjct: 620 KLEMAREKHQASQKENKQLSLKVDELERKLEATSAQNIEFLQVIAKREEAIHQSQL-RLE 678

Query: 244 NVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVI 303
                    A  L   +   + + + T+   + L + +   N  L++E  + +       
Sbjct: 679 EKTRECGTLARQLESAIEDARRQVEQTKE--HALSKERAAQNKILDLETQLSRT------ 730

Query: 304 NDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDL 363
                      KTE+   ++   + + R ++  + L D+L ++ ST    + Y+++L   
Sbjct: 731 -----------KTELSQLRRSRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKSS 779

Query: 364 HAS 366
           +A+
Sbjct: 780 YAN 782


>gi|7661880 centaurin beta1 [Homo sapiens]
          Length = 740

 Score = 30.4 bits (67), Expect = 7.9
 Identities = 34/147 (23%), Positives = 55/147 (37%), Gaps = 21/147 (14%)

Query: 296 KGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKR 355
           K D++  + D  + ++     E +V     +E+ETR+E L +L    L      L   + 
Sbjct: 4   KLDFEECLKDSPRFRASIELVEAEV-----SELETRLEKLLKLGTGLLESGRHYLAASRA 58

Query: 356 YIRYLSDLHASGDPAWQCIGAQHKWILQLMHSCKEGYVKDLKGNPGLHSPMLDLDNDTRP 415
           ++  + DL   G P              +M  C E +   L      H+ +LD    T  
Sbjct: 59  FVVGICDLARLGPPE------------PMMAECLEKFTVSLNHKLDSHAELLDATQHT-- 104

Query: 416 SVLGHLSQTASLKRGSSFQSGRDDTWR 442
             L    QT   +    F+  R D WR
Sbjct: 105 --LQQQIQTLVKEGLRGFREARRDFWR 129


>gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens]
          Length = 1910

 Score = 30.4 bits (67), Expect = 7.9
 Identities = 37/173 (21%), Positives = 75/173 (43%), Gaps = 24/173 (13%)

Query: 196 KKSEGSLAYVK---------GGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVL 246
           K  E  L+Y++         G +  +  A++ +S +   L++ GT+++E +   ++++ L
Sbjct: 636 KTEEELLSYIRENYQKTVATGEIMLYACARNMISTVKMFLKSKGTKELEVNCLNQVKSSL 695

Query: 247 NRASNTADTLFQEVLGRK-DKADSTRNA-LNVLQRFKFLFNLPLNIERNIQKGDYDVVIN 304
            + S +     ++ LG+K DK D  R   L V  R +     P     N    D + V+ 
Sbjct: 696 LKTSKS----LRQNLGKKLDKEDKVRECQLQVFLRLEMCLQCP---SINESTDDMEQVVE 748

Query: 305 DYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYI 357
           +      +   TE      Y AE    +E +  L +D + +T   L++   ++
Sbjct: 749 EVTDLLRMVCLTEDSA---YLAEF---LEEILRLYIDSIPKTLGNLYNSLGFV 795


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,536,752
Number of Sequences: 37866
Number of extensions: 1449135
Number of successful extensions: 3841
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 3812
Number of HSP's gapped (non-prelim): 47
length of query: 924
length of database: 18,247,518
effective HSP length: 112
effective length of query: 812
effective length of database: 14,006,526
effective search space: 11373299112
effective search space used: 11373299112
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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