BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|21361625 Sec5 protein [Homo sapiens] (924 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|21361625 Sec5 protein [Homo sapiens] 1839 0.0 gi|194272180 plexin B1 [Homo sapiens] 43 0.001 gi|40254442 plexin B1 [Homo sapiens] 43 0.001 gi|149363636 plexin B2 [Homo sapiens] 42 0.003 gi|157738645 plexin A4 isoform 1 [Homo sapiens] 39 0.017 gi|59710104 plexin A3 [Homo sapiens] 37 0.065 gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 35 0.42 gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 35 0.42 gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 35 0.42 gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] 35 0.42 gi|23503243 Ras association (RalGDS/AF-6) domain family (N-termi... 35 0.42 gi|64762445 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase ... 33 1.2 gi|64762406 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase ... 33 1.2 gi|8393009 chromosome 11 open reading frame2 [Homo sapiens] 33 1.6 gi|118918407 spectrin repeat containing, nuclear envelope 2 isof... 32 2.1 gi|118918403 spectrin repeat containing, nuclear envelope 2 isof... 32 2.1 gi|4505541 USO1 homolog, vesicle docking protein [Homo sapiens] 32 3.6 gi|7705720 mediator of cell motility 1 isoform 1 [Homo sapiens] 31 4.7 gi|212286159 mediator of cell motility 1 isoform 2 [Homo sapiens] 31 4.7 gi|126116589 fibrocystin L [Homo sapiens] 31 4.7 gi|229331967 RIO kinase 2 isoform 1 [Homo sapiens] 31 6.1 gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] 31 6.1 gi|120587023 down-regulated in metastasis [Homo sapiens] 30 7.9 gi|89036565 PREDICTED: similar to Temporarily Assigned Gene name... 30 7.9 gi|24430181 outer dense fiber of sperm tails 2 isoform 1 [Homo s... 30 7.9 gi|7661880 centaurin beta1 [Homo sapiens] 30 7.9 gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens] 30 7.9 >gi|21361625 Sec5 protein [Homo sapiens] Length = 924 Score = 1839 bits (4764), Expect = 0.0 Identities = 924/924 (100%), Positives = 924/924 (100%) Query: 1 MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKI 60 MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKI Sbjct: 1 MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKI 60 Query: 61 VCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDR 120 VCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDR Sbjct: 61 VCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDR 120 Query: 121 NKGIPPLSLRPANPLGIEIEKSKFSQKDLEMLFHGMSADFTSENFSAAWYLIENHSNTSF 180 NKGIPPLSLRPANPLGIEIEKSKFSQKDLEMLFHGMSADFTSENFSAAWYLIENHSNTSF Sbjct: 121 NKGIPPLSLRPANPLGIEIEKSKFSQKDLEMLFHGMSADFTSENFSAAWYLIENHSNTSF 180 Query: 181 EQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQ 240 EQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQ Sbjct: 181 EQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQ 240 Query: 241 KLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYD 300 KLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYD Sbjct: 241 KLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYD 300 Query: 301 VVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYL 360 VVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYL Sbjct: 301 VVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYL 360 Query: 361 SDLHASGDPAWQCIGAQHKWILQLMHSCKEGYVKDLKGNPGLHSPMLDLDNDTRPSVLGH 420 SDLHASGDPAWQCIGAQHKWILQLMHSCKEGYVKDLKGNPGLHSPMLDLDNDTRPSVLGH Sbjct: 361 SDLHASGDPAWQCIGAQHKWILQLMHSCKEGYVKDLKGNPGLHSPMLDLDNDTRPSVLGH 420 Query: 421 LSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFS 480 LSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFS Sbjct: 421 LSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFS 480 Query: 481 ETAEKSGQIERSKNVRQRQNDFKKMIQEVMHSLVKLTRGALLPLSIRDGEAKQYGGWEVK 540 ETAEKSGQIERSKNVRQRQNDFKKMIQEVMHSLVKLTRGALLPLSIRDGEAKQYGGWEVK Sbjct: 481 ETAEKSGQIERSKNVRQRQNDFKKMIQEVMHSLVKLTRGALLPLSIRDGEAKQYGGWEVK 540 Query: 541 CELSGQWLAHAIQTVRLTHESLTALEIPNDLLQTIQDLILDLRVRCVMATLQHTAEEIKR 600 CELSGQWLAHAIQTVRLTHESLTALEIPNDLLQTIQDLILDLRVRCVMATLQHTAEEIKR Sbjct: 541 CELSGQWLAHAIQTVRLTHESLTALEIPNDLLQTIQDLILDLRVRCVMATLQHTAEEIKR 600 Query: 601 LAEKEDWIVDNEGLTSLPCQFEQCIVCSLQSLKGVLECKPGEASVFQQPKTQEEVCQLSI 660 LAEKEDWIVDNEGLTSLPCQFEQCIVCSLQSLKGVLECKPGEASVFQQPKTQEEVCQLSI Sbjct: 601 LAEKEDWIVDNEGLTSLPCQFEQCIVCSLQSLKGVLECKPGEASVFQQPKTQEEVCQLSI 660 Query: 661 NIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCY 720 NIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCY Sbjct: 661 NIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCY 720 Query: 721 LERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLEPGIY 780 LERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLEPGIY Sbjct: 721 LERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLEPGIY 780 Query: 781 AGYFDWKDCLPPTGVRNYLKEALVNIIAVHAEVFTISKELVPRVLSKVIEAVSEELSRLM 840 AGYFDWKDCLPPTGVRNYLKEALVNIIAVHAEVFTISKELVPRVLSKVIEAVSEELSRLM Sbjct: 781 AGYFDWKDCLPPTGVRNYLKEALVNIIAVHAEVFTISKELVPRVLSKVIEAVSEELSRLM 840 Query: 841 QCVSSFSKNGALQARLEICALRDTVAVYLTPESKSSFKQALEALPQLSSGADKKLLEELL 900 QCVSSFSKNGALQARLEICALRDTVAVYLTPESKSSFKQALEALPQLSSGADKKLLEELL Sbjct: 841 QCVSSFSKNGALQARLEICALRDTVAVYLTPESKSSFKQALEALPQLSSGADKKLLEELL 900 Query: 901 NKFKSSMHLQLTCFQAASSTMMKT 924 NKFKSSMHLQLTCFQAASSTMMKT Sbjct: 901 NKFKSSMHLQLTCFQAASSTMMKT 924 >gi|194272180 plexin B1 [Homo sapiens] Length = 2135 Score = 43.1 bits (100), Expect = 0.001 Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 5/94 (5%) Query: 8 PLVTGISPNEGIP--WTKVTIRGENLGTGPTDLIGL-TICGHNCLLTA-EWMSASKIVCR 63 PL+ + P G T+VTIRG NLG D++G+ T+ G C + A E+ +S +VC Sbjct: 1070 PLIHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCI 1129 Query: 64 VGQAKND-KGDIIVTTKSGGRGTSTVSFKLLKPE 96 G + + G V GRG S F P+ Sbjct: 1130 TGASGEEVAGATAVEVPGRGRGVSEHDFAYQDPK 1163 >gi|40254442 plexin B1 [Homo sapiens] Length = 2135 Score = 43.1 bits (100), Expect = 0.001 Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 5/94 (5%) Query: 8 PLVTGISPNEGIP--WTKVTIRGENLGTGPTDLIGL-TICGHNCLLTA-EWMSASKIVCR 63 PL+ + P G T+VTIRG NLG D++G+ T+ G C + A E+ +S +VC Sbjct: 1070 PLIHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCI 1129 Query: 64 VGQAKND-KGDIIVTTKSGGRGTSTVSFKLLKPE 96 G + + G V GRG S F P+ Sbjct: 1130 TGASGEEVAGATAVEVPGRGRGVSEHDFAYQDPK 1163 >gi|149363636 plexin B2 [Homo sapiens] Length = 1838 Score = 42.0 bits (97), Expect = 0.003 Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 5/102 (4%) Query: 7 PPLVTGISPNEGI--PWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSAS-KIVCR 63 PP++T I P G ++TI G NLG D+ +++ G NC E S S +IVC Sbjct: 802 PPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISVAGRNCSFQPERYSVSTRIVCV 861 Query: 64 VGQAKNDKGDIIVTTKSG--GRGTSTVSFKLLKPEKIGILDQ 103 + A+ + G GR V F +P+ + + Q Sbjct: 862 IEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSVEPQ 903 >gi|157738645 plexin A4 isoform 1 [Homo sapiens] Length = 1894 Score = 39.3 bits (90), Expect = 0.017 Identities = 28/61 (45%), Positives = 36/61 (59%), Gaps = 6/61 (9%) Query: 10 VTGISPNEGIPWTKVTIRGENLGTGPTDLIG-LTICGHNCL-LTAEWMSASKIVCRVGQA 67 VTG P EG TKVTIRGENLG D+ + + G C L ++ A +IVC +G+A Sbjct: 866 VTG--PREG--GTKVTIRGENLGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEA 921 Query: 68 K 68 K Sbjct: 922 K 922 >gi|59710104 plexin A3 [Homo sapiens] Length = 1871 Score = 37.4 bits (85), Expect = 0.065 Identities = 22/56 (39%), Positives = 35/56 (62%), Gaps = 4/56 (7%) Query: 13 ISPNEGIPWTKVTIRGENLGTGPTDLIGLTICGHNC-LLTAEWMSASKIVCRVGQA 67 + P EG T+VTI G+NLG + +GL + G C + AE++SA +IVC + ++ Sbjct: 849 VGPKEG--GTRVTIVGDNLGLLSRE-VGLRVAGVRCNSIPAEYISAERIVCEMEES 901 >gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] Length = 3333 Score = 34.7 bits (78), Expect = 0.42 Identities = 47/212 (22%), Positives = 86/212 (40%), Gaps = 49/212 (23%) Query: 173 ENHSNTSFEQLKMAVTNLKRQANKKS------EGSLAYVKGGLSTFFEAQDAL------- 219 E H+ S ++L + +KR A+ + + AY + L+ A+DA Sbjct: 2143 EKHAR-SLQELAKQLEEIKRNASGDELVRCAVDAATAY-ENILNAIKAAEDAANRAASAS 2200 Query: 220 -SAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQ 278 SA+ ++ D K + +++ + +LN A T L QEV ++ + LN++ Sbjct: 2201 ESALQTVIKEDLPRKAK-TLSSNSDKLLNEAKMTQKKLKQEV---SPALNNLQQTLNIVT 2256 Query: 279 RFKFLFNLPLNIERN----IQKGDYDVVIN-------------------------DYEKA 309 K + + L R+ IQ+GD D +I+ D E+ Sbjct: 2257 VQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERI 2316 Query: 310 KSLFGKTEVQVFKKYYAEVETRIEALRELLLD 341 K +G+T+ + FKK + + + L L D Sbjct: 2317 KDTYGRTQNEDFKKALTDADNSVNKLTNKLPD 2348 >gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] Length = 1668 Score = 34.7 bits (78), Expect = 0.42 Identities = 47/212 (22%), Positives = 86/212 (40%), Gaps = 49/212 (23%) Query: 173 ENHSNTSFEQLKMAVTNLKRQANKKS------EGSLAYVKGGLSTFFEAQDAL------- 219 E H+ S ++L + +KR A+ + + AY + L+ A+DA Sbjct: 478 EKHAR-SLQELAKQLEEIKRNASGDELVRCAVDAATAY-ENILNAIKAAEDAANRAASAS 535 Query: 220 -SAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQ 278 SA+ ++ D K + +++ + +LN A T L QEV ++ + LN++ Sbjct: 536 ESALQTVIKEDLPRKAK-TLSSNSDKLLNEAKMTQKKLKQEV---SPALNNLQQTLNIVT 591 Query: 279 RFKFLFNLPLNIERN----IQKGDYDVVIN-------------------------DYEKA 309 K + + L R+ IQ+GD D +I+ D E+ Sbjct: 592 VQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERI 651 Query: 310 KSLFGKTEVQVFKKYYAEVETRIEALRELLLD 341 K +G+T+ + FKK + + + L L D Sbjct: 652 KDTYGRTQNEDFKKALTDADNSVNKLTNKLPD 683 >gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] Length = 3277 Score = 34.7 bits (78), Expect = 0.42 Identities = 47/212 (22%), Positives = 86/212 (40%), Gaps = 49/212 (23%) Query: 173 ENHSNTSFEQLKMAVTNLKRQANKKS------EGSLAYVKGGLSTFFEAQDAL------- 219 E H+ S ++L + +KR A+ + + AY + L+ A+DA Sbjct: 2087 EKHAR-SLQELAKQLEEIKRNASGDELVRCAVDAATAY-ENILNAIKAAEDAANRAASAS 2144 Query: 220 -SAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQ 278 SA+ ++ D K + +++ + +LN A T L QEV ++ + LN++ Sbjct: 2145 ESALQTVIKEDLPRKAK-TLSSNSDKLLNEAKMTQKKLKQEV---SPALNNLQQTLNIVT 2200 Query: 279 RFKFLFNLPLNIERN----IQKGDYDVVIN-------------------------DYEKA 309 K + + L R+ IQ+GD D +I+ D E+ Sbjct: 2201 VQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERI 2260 Query: 310 KSLFGKTEVQVFKKYYAEVETRIEALRELLLD 341 K +G+T+ + FKK + + + L L D Sbjct: 2261 KDTYGRTQNEDFKKALTDADNSVNKLTNKLPD 2292 >gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] Length = 1724 Score = 34.7 bits (78), Expect = 0.42 Identities = 47/212 (22%), Positives = 86/212 (40%), Gaps = 49/212 (23%) Query: 173 ENHSNTSFEQLKMAVTNLKRQANKKS------EGSLAYVKGGLSTFFEAQDAL------- 219 E H+ S ++L + +KR A+ + + AY + L+ A+DA Sbjct: 534 EKHAR-SLQELAKQLEEIKRNASGDELVRCAVDAATAY-ENILNAIKAAEDAANRAASAS 591 Query: 220 -SAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQ 278 SA+ ++ D K + +++ + +LN A T L QEV ++ + LN++ Sbjct: 592 ESALQTVIKEDLPRKAK-TLSSNSDKLLNEAKMTQKKLKQEV---SPALNNLQQTLNIVT 647 Query: 279 RFKFLFNLPLNIERN----IQKGDYDVVIN-------------------------DYEKA 309 K + + L R+ IQ+GD D +I+ D E+ Sbjct: 648 VQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERI 707 Query: 310 KSLFGKTEVQVFKKYYAEVETRIEALRELLLD 341 K +G+T+ + FKK + + + L L D Sbjct: 708 KDTYGRTQNEDFKKALTDADNSVNKLTNKLPD 739 >gi|23503243 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 [Homo sapiens] Length = 392 Score = 34.7 bits (78), Expect = 0.42 Identities = 29/126 (23%), Positives = 59/126 (46%), Gaps = 6/126 (4%) Query: 235 EGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNAL--NVLQRFKFLFNLPLNIER 292 +G T+ + VLN TAD L + + + +K S L N ++ + N+E Sbjct: 145 KGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEE 204 Query: 293 NIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHD 352 I + + + ND E + F + E+Q+ ++ +++ +++ +R+ K+ E + L D Sbjct: 205 EIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQ----KITECENKLKD 260 Query: 353 QKRYIR 358 IR Sbjct: 261 YLAQIR 266 >gi|64762445 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 isoform b [Homo sapiens] Length = 471 Score = 33.1 bits (74), Expect = 1.2 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 4/76 (5%) Query: 622 EQCIVCSLQSLKGVLECKPGEASVFQQPKTQEEVCQLSINIMQ---VFIYCLEQLSTKPD 678 +QC + +L+ +K L + G+ +VF T E + +N + ++ +E + PD Sbjct: 103 KQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDDPD 162 Query: 679 ADIDTTHLSVDVSSPD 694 I L V VSSPD Sbjct: 163 V-IAANILEVKVSSPD 177 >gi|64762406 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 isoform a [Homo sapiens] Length = 505 Score = 33.1 bits (74), Expect = 1.2 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 4/76 (5%) Query: 622 EQCIVCSLQSLKGVLECKPGEASVFQQPKTQEEVCQLSINIMQ---VFIYCLEQLSTKPD 678 +QC + +L+ +K L + G+ +VF T E + +N + ++ +E + PD Sbjct: 103 KQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDDPD 162 Query: 679 ADIDTTHLSVDVSSPD 694 I L V VSSPD Sbjct: 163 V-IAANILEVKVSSPD 177 >gi|8393009 chromosome 11 open reading frame2 [Homo sapiens] Length = 782 Score = 32.7 bits (73), Expect = 1.6 Identities = 43/215 (20%), Positives = 83/215 (38%), Gaps = 14/215 (6%) Query: 159 DFTSENFSAAWYLIENHSNTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDA 218 D +F YL + QL + T++ RQ V + F A D Sbjct: 62 DLNGAHFDPEVYLDKLRRECPLAQLMDSETDMVRQIRALDSDMQTLVYENYNKFISATDT 121 Query: 219 LSAIHQKLEADGTEKVEGSMTQKLEN--VLNRASNTADTLFQEVLGRKDKADSTRNALNV 276 + +K++ D K+E M + N V+ S Q+ R ++ + Sbjct: 122 I----RKMKND-FRKMEDEMDRLATNMAVITDFSARISATLQD---RHERITKLAGVHAL 173 Query: 277 LQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTE-VQVFKKYYAEVETRIEAL 335 L++ +FLF LP + + ++ G Y + +A+++ + + + F+ + + L Sbjct: 174 LRKLQFLFELPSRLTKCVELGAYGQAVRYQGRAQAVLQQYQHLPSFRAIQDDCQVITARL 233 Query: 336 RELLLDKLLETPSTLHDQKRYIRYLSDLHASGDPA 370 + L + E S +Q + L A G+PA Sbjct: 234 AQQLRQRFREGGSGAPEQAECVELLL---ALGEPA 265 >gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5 [Homo sapiens] Length = 6907 Score = 32.3 bits (72), Expect = 2.1 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 5/103 (4%) Query: 818 KELVPRVLSKVIEAVSEELSRLMQCVSSFSKNGALQARLEICALRDTVAVYLTPESKSSF 877 +E +P + A +EELS L+ C+ + +N Q L L+ ++ PES Sbjct: 3489 QEELPEISKTKEAATTEELSELLDCLCQYGENVEKQQLLLTLLLQRIRSIQNVPESSG-- 3546 Query: 878 KQALEALPQLSS-GADKKLLEELLNKFKSSMHLQLTCFQAASS 919 A+E +P + K+ +LL K + + L T Q S Sbjct: 3547 --AVETVPAFQEITSMKERCNKLLQKVQKNKELVQTEIQERHS 3587 >gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1 [Homo sapiens] Length = 6885 Score = 32.3 bits (72), Expect = 2.1 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 5/103 (4%) Query: 818 KELVPRVLSKVIEAVSEELSRLMQCVSSFSKNGALQARLEICALRDTVAVYLTPESKSSF 877 +E +P + A +EELS L+ C+ + +N Q L L+ ++ PES Sbjct: 3489 QEELPEISKTKEAATTEELSELLDCLCQYGENVEKQQLLLTLLLQRIRSIQNVPESSG-- 3546 Query: 878 KQALEALPQLSS-GADKKLLEELLNKFKSSMHLQLTCFQAASS 919 A+E +P + K+ +LL K + + L T Q S Sbjct: 3547 --AVETVPAFQEITSMKERCNKLLQKVQKNKELVQTEIQERHS 3587 >gi|4505541 USO1 homolog, vesicle docking protein [Homo sapiens] Length = 962 Score = 31.6 bits (70), Expect = 3.6 Identities = 41/183 (22%), Positives = 73/183 (39%), Gaps = 8/183 (4%) Query: 138 EIEKSKFSQKDLEMLFHGMSADFTSENFSAAWYLIENHSNTSFEQLKMAVTNLKRQANKK 197 E+ +S+ ++KD + M + TS + ++ + +LK + LK Q N + Sbjct: 747 ELLQSQLTEKD--SMIENMKSSQTSGTNEQSSAIVSARDSEQVAELKQELATLKSQLNSQ 804 Query: 198 SEG--SLAYVKGGLSTFFEAQDALSAIHQKLE---ADGTEKVEGSMTQKLENVLNRASNT 252 S L K L EA + + E A T VEG ++ L+ N Sbjct: 805 SVEITKLQTEKQELLQKTEAFAKSVEVQGETETIIATKTTDVEGRLSALLQET-KELKNE 863 Query: 253 ADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSL 312 L +E K++ DS+ + + +LQ K L + + Q ++ + +K SL Sbjct: 864 IKALSEERTAIKEQLDSSNSTIAILQTEKDKLELEITDSKKEQDDLLVLLADQDQKILSL 923 Query: 313 FGK 315 K Sbjct: 924 KNK 926 >gi|7705720 mediator of cell motility 1 isoform 1 [Homo sapiens] Length = 297 Score = 31.2 bits (69), Expect = 4.7 Identities = 18/84 (21%), Positives = 40/84 (47%), Gaps = 1/84 (1%) Query: 696 FGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKEL 755 FG + + L L +V S+ C+ + + + + ++ IE + ++ M+ +++L Sbjct: 169 FGKLFSKY-LADPSNLFVVSSDFCHWGQRFRYSYYDESQGEIYRSIEHLDKMGMSIIEQL 227 Query: 756 DQRLFENYIELKADPIVGSLEPGI 779 D F NY++ + I G G+ Sbjct: 228 DPVSFSNYLKKYHNTICGRHPIGV 251 >gi|212286159 mediator of cell motility 1 isoform 2 [Homo sapiens] Length = 274 Score = 31.2 bits (69), Expect = 4.7 Identities = 18/84 (21%), Positives = 40/84 (47%), Gaps = 1/84 (1%) Query: 696 FGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKEL 755 FG + + L L +V S+ C+ + + + + ++ IE + ++ M+ +++L Sbjct: 146 FGKLFSKY-LADPSNLFVVSSDFCHWGQRFRYSYYDESQGEIYRSIEHLDKMGMSIIEQL 204 Query: 756 DQRLFENYIELKADPIVGSLEPGI 779 D F NY++ + I G G+ Sbjct: 205 DPVSFSNYLKKYHNTICGRHPIGV 228 >gi|126116589 fibrocystin L [Homo sapiens] Length = 4243 Score = 31.2 bits (69), Expect = 4.7 Identities = 15/31 (48%), Positives = 18/31 (58%) Query: 8 PLVTGISPNEGIPWTKVTIRGENLGTGPTDL 38 P +TG+ PN I KV I GE LGT D+ Sbjct: 1749 PYITGVFPNSVIGSVKVLIEGEGLGTVLEDI 1779 >gi|229331967 RIO kinase 2 isoform 1 [Homo sapiens] Length = 552 Score = 30.8 bits (68), Expect = 6.1 Identities = 25/113 (22%), Positives = 51/113 (45%), Gaps = 4/113 (3%) Query: 171 LIENHSNTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADG 230 ++EN+S T F + K N RQ ++ +G + ALS+++++ Sbjct: 407 VVENNSVTEFSEEKNRTENYNRQDGQRVQGGVPAGSDEYEDECPHLIALSSLNREFRPFR 466 Query: 231 TEKVEGSMTQKLENVLNRASN----TADTLFQEVLGRKDKADSTRNALNVLQR 279 E+ G+M Q L+ S+ + T+ E++ +K K T+ + ++R Sbjct: 467 DEENVGAMNQYRTRTLSITSSGSAVSCSTIPPELVKQKVKRQLTKQQKSAVRR 519 >gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] Length = 4646 Score = 30.8 bits (68), Expect = 6.1 Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 17/91 (18%) Query: 489 IERSKNVRQRQNDFKKMIQEVMHSLVKLTRGALLPLSIRDGEAKQYGGWEVKCELS---- 544 I SKNV + Q FKKM V ++ +L +S R+GE + K +S Sbjct: 1641 IGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMF-----KTPVSITEH 1695 Query: 545 ---GQWLAHAIQTVRLT-----HESLTALEI 567 +WL + +R+T ES+T +EI Sbjct: 1696 PKINEWLTLVEKEMRVTLAKLLAESVTEVEI 1726 >gi|120587023 down-regulated in metastasis [Homo sapiens] Length = 2785 Score = 30.4 bits (67), Expect = 7.9 Identities = 31/143 (21%), Positives = 59/143 (41%), Gaps = 16/143 (11%) Query: 490 ERSKNVRQRQNDFKKMIQEVMHSL----VKLTRGALLPLSIRDGEAKQYGGWEVKCELSG 545 E+ + V Q + K ++ + HS VKL L P++ E + +L Sbjct: 219 EKVEGVGQLLFEMCKGVRNMFHSCTGQAVKLILRKLGPVT------------ETETQLPW 266 Query: 546 QWLAHAIQTVRLTHESLTALEIPNDLLQTIQDLILDLRVRCVMATLQHTAEEIKRLAEKE 605 + ++ + + S + E + +Q+ +LDL + ++E+IKRL E Sbjct: 267 MLIGETLKNMVKSTVSYISKEHFGTFFECLQESLLDLHTKVTKTNCCESSEQIKRLLETY 326 Query: 606 DWIVDNEGLTSLPCQFEQCIVCS 628 +V + T +P + C V S Sbjct: 327 LILVKHGSGTKIPTPADVCKVLS 349 >gi|89036565 PREDICTED: similar to Temporarily Assigned Gene name family member (tag-184) [Homo sapiens] Length = 2785 Score = 30.4 bits (67), Expect = 7.9 Identities = 31/143 (21%), Positives = 59/143 (41%), Gaps = 16/143 (11%) Query: 490 ERSKNVRQRQNDFKKMIQEVMHSL----VKLTRGALLPLSIRDGEAKQYGGWEVKCELSG 545 E+ + V Q + K ++ + HS VKL L P++ E + +L Sbjct: 219 EKVEGVGQLLFEMCKGVRNMFHSCTGQAVKLILRKLGPVT------------ETETQLPW 266 Query: 546 QWLAHAIQTVRLTHESLTALEIPNDLLQTIQDLILDLRVRCVMATLQHTAEEIKRLAEKE 605 + ++ + + S + E + +Q+ +LDL + ++E+IKRL E Sbjct: 267 MLIGETLKNMVKSTVSYISKEHFGTFFECLQESLLDLHTKVTKTNCCESSEQIKRLLETY 326 Query: 606 DWIVDNEGLTSLPCQFEQCIVCS 628 +V + T +P + C V S Sbjct: 327 LILVKHGSGTKIPTPADVCKVLS 349 >gi|24430181 outer dense fiber of sperm tails 2 isoform 1 [Homo sapiens] Length = 805 Score = 30.4 bits (67), Expect = 7.9 Identities = 34/183 (18%), Positives = 73/183 (39%), Gaps = 20/183 (10%) Query: 184 KMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLE 243 K+ + K QA++K L+ L EA A + ++ A E + S +LE Sbjct: 620 KLEMAREKHQASQKENKQLSLKVDELERKLEATSAQNIEFLQVIAKREEAIHQSQL-RLE 678 Query: 244 NVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVI 303 A L + + + + T+ + L + + N L++E + + Sbjct: 679 EKTRECGTLARQLESAIEDARRQVEQTKE--HALSKERAAQNKILDLETQLSRT------ 730 Query: 304 NDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDL 363 KTE+ ++ + + R ++ + L D+L ++ ST + Y+++L Sbjct: 731 -----------KTELSQLRRSRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKSS 779 Query: 364 HAS 366 +A+ Sbjct: 780 YAN 782 >gi|7661880 centaurin beta1 [Homo sapiens] Length = 740 Score = 30.4 bits (67), Expect = 7.9 Identities = 34/147 (23%), Positives = 55/147 (37%), Gaps = 21/147 (14%) Query: 296 KGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKR 355 K D++ + D + ++ E +V +E+ETR+E L +L L L + Sbjct: 4 KLDFEECLKDSPRFRASIELVEAEV-----SELETRLEKLLKLGTGLLESGRHYLAASRA 58 Query: 356 YIRYLSDLHASGDPAWQCIGAQHKWILQLMHSCKEGYVKDLKGNPGLHSPMLDLDNDTRP 415 ++ + DL G P +M C E + L H+ +LD T Sbjct: 59 FVVGICDLARLGPPE------------PMMAECLEKFTVSLNHKLDSHAELLDATQHT-- 104 Query: 416 SVLGHLSQTASLKRGSSFQSGRDDTWR 442 L QT + F+ R D WR Sbjct: 105 --LQQQIQTLVKEGLRGFREARRDFWR 129 >gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens] Length = 1910 Score = 30.4 bits (67), Expect = 7.9 Identities = 37/173 (21%), Positives = 75/173 (43%), Gaps = 24/173 (13%) Query: 196 KKSEGSLAYVK---------GGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVL 246 K E L+Y++ G + + A++ +S + L++ GT+++E + ++++ L Sbjct: 636 KTEEELLSYIRENYQKTVATGEIMLYACARNMISTVKMFLKSKGTKELEVNCLNQVKSSL 695 Query: 247 NRASNTADTLFQEVLGRK-DKADSTRNA-LNVLQRFKFLFNLPLNIERNIQKGDYDVVIN 304 + S + ++ LG+K DK D R L V R + P N D + V+ Sbjct: 696 LKTSKS----LRQNLGKKLDKEDKVRECQLQVFLRLEMCLQCP---SINESTDDMEQVVE 748 Query: 305 DYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYI 357 + + TE Y AE +E + L +D + +T L++ ++ Sbjct: 749 EVTDLLRMVCLTEDSA---YLAEF---LEEILRLYIDSIPKTLGNLYNSLGFV 795 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.133 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 33,536,752 Number of Sequences: 37866 Number of extensions: 1449135 Number of successful extensions: 3841 Number of sequences better than 10.0: 27 Number of HSP's better than 10.0 without gapping: 2 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 3812 Number of HSP's gapped (non-prelim): 47 length of query: 924 length of database: 18,247,518 effective HSP length: 112 effective length of query: 812 effective length of database: 14,006,526 effective search space: 11373299112 effective search space used: 11373299112 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.