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Search of human proteins with 21361462
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361462 EH-domain containing 2 [Homo sapiens]
(543 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361462 EH-domain containing 2 [Homo sapiens] 1093 0.0
gi|30240932 EH-domain containing 1 [Homo sapiens] 780 0.0
gi|7657056 EH-domain containing 3 [Homo sapiens] 778 0.0
gi|21264315 EH-domain containing 4 [Homo sapiens] 745 0.0
gi|149363672 sarcalumenin [Homo sapiens] 213 3e-55
gi|4503593 epidermal growth factor receptor pathway substrate 15... 104 2e-22
gi|10864047 epidermal growth factor receptor pathway substrate 1... 103 4e-22
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 78 2e-14
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 78 2e-14
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 77 3e-14
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 77 3e-14
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 77 3e-14
gi|190886435 RALBP1 associated Eps domain containing 1 isoform a... 69 1e-11
gi|190886437 RALBP1 associated Eps domain containing 1 isoform b... 69 1e-11
gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1... 61 2e-09
gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2... 61 3e-09
gi|4557537 developmentally regulated GTP binding protein 2 [Homo... 36 0.10
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 33 0.67
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 33 0.67
gi|7661622 hypothetical protein LOC25906 [Homo sapiens] 32 1.5
gi|40217805 nucleolar protein 9 [Homo sapiens] 31 2.5
gi|40068065 hypothetical protein LOC54058 [Homo sapiens] 31 3.3
gi|94681049 hypothetical protein LOC80217 [Homo sapiens] 30 4.3
gi|22749217 coiled-coil domain containing 63 [Homo sapiens] 30 4.3
gi|45331213 RAN binding protein 6 [Homo sapiens] 30 5.6
gi|4758796 developmentally regulated GTP binding protein 1 [Homo... 30 7.4
gi|22749443 EF-hand domain family, member A1 [Homo sapiens] 30 7.4
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] 29 9.6
gi|148664201 cytoskeleton associated protein 2 isoform 2 [Homo s... 29 9.6
gi|148664244 cytoskeleton associated protein 2 isoform 1 [Homo s... 29 9.6
>gi|21361462 EH-domain containing 2 [Homo sapiens]
Length = 543
Score = 1093 bits (2826), Expect = 0.0
Identities = 543/543 (100%), Positives = 543/543 (100%)
Query: 1 MFSWLKRGGARGQQPEAIRTVTSALKELYRTKLLPLEEHYRFGAFHSPALEDADFDGKPM 60
MFSWLKRGGARGQQPEAIRTVTSALKELYRTKLLPLEEHYRFGAFHSPALEDADFDGKPM
Sbjct: 1 MFSWLKRGGARGQQPEAIRTVTSALKELYRTKLLPLEEHYRFGAFHSPALEDADFDGKPM 60
Query: 61 VLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGDTEGTVPGNALVVDPDK 120
VLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGDTEGTVPGNALVVDPDK
Sbjct: 61 VLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGDTEGTVPGNALVVDPDK 120
Query: 121 PFRKLNPFGNTFLNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAE 180
PFRKLNPFGNTFLNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAE
Sbjct: 121 PFRKLNPFGNTFLNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAE 180
Query: 181 RVDLIILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWAL 240
RVDLIILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWAL
Sbjct: 181 RVDLIILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWAL 240
Query: 241 GKVVGTPEVLRVYIGSFWSQPLLVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKR 300
GKVVGTPEVLRVYIGSFWSQPLLVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKR
Sbjct: 241 GKVVGTPEVLRVYIGSFWSQPLLVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKR 300
Query: 301 ARLVRVHAYIISYLKKEMPSVFGKENKKKQLILKLPVIFAKIQLEHHISPGDFPDCQKMQ 360
ARLVRVHAYIISYLKKEMPSVFGKENKKKQLILKLPVIFAKIQLEHHISPGDFPDCQKMQ
Sbjct: 301 ARLVRVHAYIISYLKKEMPSVFGKENKKKQLILKLPVIFAKIQLEHHISPGDFPDCQKMQ 360
Query: 361 ELLMAHDFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEELESTEVGVQGGAFEGTHMG 420
ELLMAHDFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEELESTEVGVQGGAFEGTHMG
Sbjct: 361 ELLMAHDFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEELESTEVGVQGGAFEGTHMG 420
Query: 421 PFVERGPDEAMEDGEEGSDDEAEWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTK 480
PFVERGPDEAMEDGEEGSDDEAEWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTK
Sbjct: 421 PFVERGPDEAMEDGEEGSDDEAEWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTK 480
Query: 481 LPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRRHKG 540
LPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRRHKG
Sbjct: 481 LPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRRHKG 540
Query: 541 SAE 543
SAE
Sbjct: 541 SAE 543
>gi|30240932 EH-domain containing 1 [Homo sapiens]
Length = 534
Score = 780 bits (2013), Expect = 0.0
Identities = 380/539 (70%), Positives = 446/539 (82%), Gaps = 5/539 (0%)
Query: 1 MFSWLKRGGARGQQPEAIRTVTSALKELYRTKLLPLEEHYRFGAFHSPALEDADFDGKPM 60
MFSW+ + R ++PE +TV L++LY KLLPLEEHYRF FHSPALEDADFD KPM
Sbjct: 1 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM 60
Query: 61 VLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGDTEGTVPGNALVVDPDK 120
VL+ GQYSTGKT+FI++L+EQ+ PG R+GPEPTTD F+AVMHG TEG VPGNALVVDP +
Sbjct: 61 VLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRR 120
Query: 121 PFRKLNPFGNTFLNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAE 180
PFRKLN FGN FLNRFMCAQLPN VL+SISIIDTPGILSG KQR+SRGYDF AVL WFAE
Sbjct: 121 PFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAE 180
Query: 181 RVDLIILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWAL 240
RVD IILLFDAHKL+ISDEFSE I AL+ HEDKIRVVLNKAD +ETQQLMRVYGALMW+L
Sbjct: 181 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSL 240
Query: 241 GKVVGTPEVLRVYIGSFWSQPLLVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKR 300
GK++ TPEV+RVYIGSFWS PLL+PDNR+LFE EEQDLF+DIQ LPR+AALRKLNDL+KR
Sbjct: 241 GKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKR 300
Query: 301 ARLVRVHAYIISYLKKEMPSVFGKENKKKQLILKLPVIFAKIQLEHHISPGDFPDCQKMQ 360
ARL +VHAYIIS LKKEMP+VFGKE+KKK+L+ L I+ KI+ EH ISPGDFP +KMQ
Sbjct: 301 ARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQ 360
Query: 361 ELLMAHDFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEELESTEVGVQGGAFEGTHMG 420
ELL DF+KF +LKPKLL+ +D+ML +DIA+LM ++RQEE V+GGAF+GT G
Sbjct: 361 ELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNG 420
Query: 421 PFVERGPDEAMEDGEEGSDDEAEWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTK 480
PF +G D+ EWVV KDK YDEIFY L+P +GK++G+ AK MV +K
Sbjct: 421 PF-----GHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSK 475
Query: 481 LPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRRHK 539
LPN+VLG+IWKL+DVD+DG+LDDEEFALA+HLI+ KLEGH LPA+LP LVPPSKRRH+
Sbjct: 476 LPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE 534
>gi|7657056 EH-domain containing 3 [Homo sapiens]
Length = 535
Score = 778 bits (2010), Expect = 0.0
Identities = 381/537 (70%), Positives = 443/537 (82%), Gaps = 5/537 (0%)
Query: 1 MFSWLKRGGARGQQPEAIRTVTSALKELYRTKLLPLEEHYRFGAFHSPALEDADFDGKPM 60
MFSWL R + PE +TV+ LK+LY++KLLPLEEHYRF FHSPALEDADFD KPM
Sbjct: 1 MFSWLGTDDRRRKDPEVFQTVSEGLKKLYKSKLLPLEEHYRFHEFHSPALEDADFDNKPM 60
Query: 61 VLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGDTEGTVPGNALVVDPDK 120
VL+ GQYSTGKT+FI+YLLEQ+ PG R+GPEPTTD F+AVM GD EG +PGNALVVDP K
Sbjct: 61 VLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDMEGIIPGNALVVDPKK 120
Query: 121 PFRKLNPFGNTFLNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAE 180
PFRKLN FGN FLNRF+CAQLPN VLESIS+IDTPGILSG KQR+SRGYDF AVL WFAE
Sbjct: 121 PFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAE 180
Query: 181 RVDLIILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWAL 240
RVD IILLFDAHKL+ISDEFSE I AL+ HEDK+RVVLNKAD +ETQQLMRVYGALMW+L
Sbjct: 181 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSL 240
Query: 241 GKVVGTPEVLRVYIGSFWSQPLLVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKR 300
GK+V TPEV+RVYIGSFWS PLL+PDNR+LFE EEQDLFRDIQ LPR+AALRKLNDL+KR
Sbjct: 241 GKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKR 300
Query: 301 ARLVRVHAYIISYLKKEMPSVFGKENKKKQLILKLPVIFAKIQLEHHISPGDFPDCQKMQ 360
ARL +VHAYIIS LKKEMPSVFGK+NKKK+L+ L I+ +I+ EH ISPGDFP+ ++MQ
Sbjct: 301 ARLAKVHAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQ 360
Query: 361 ELLMAHDFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEELESTEVGVQGGAFEGTHMG 420
+ L A DF+KF LK KLLE +D+ML HDIA+LM L+RQEE + V+GGAFEGT G
Sbjct: 361 DQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRPIQMVKGGAFEGTLHG 420
Query: 421 PFVERGPDEAMEDGEEGSDDEAEWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTK 480
PF +G D+AEWVV +DK YDEIFY L+P DGK++G+ AK MV +K
Sbjct: 421 PF-----GHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSK 475
Query: 481 LPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRR 537
LPNSVLG+IWKL+D+D+DGMLDD+EFALA+HLI+ KLEGH LP LP L+PPSKR+
Sbjct: 476 LPNSVLGKIWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLLPPSKRK 532
>gi|21264315 EH-domain containing 4 [Homo sapiens]
Length = 541
Score = 745 bits (1923), Expect = 0.0
Identities = 372/546 (68%), Positives = 443/546 (81%), Gaps = 8/546 (1%)
Query: 1 MFSWLKR---GGARGQQPEAIRTVTSALKELYRTKLLPLEEHYRFGAFHSPALEDADFDG 57
MFSW+ R G R +A++TVT L+ LY K+LPLEE YRF FHSPALEDADF+
Sbjct: 1 MFSWMGRQAGGRERAGGADAVQTVTGGLRSLYLRKVLPLEEAYRFHEFHSPALEDADFEN 60
Query: 58 KPMVLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGDTEGTVPGNALVVD 117
KPM+L+ GQYSTGKT+FI+YLLEQ+ PG R+GPEPTTD F+AVM+G+TEG+ PGNALVVD
Sbjct: 61 KPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVD 120
Query: 118 PDKPFRKLNPFGNTFLNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRW 177
P KPFRKL+ FGN FLNRFMC+QLPNQVL+SIS+ID+PGILSG KQR+SRGYDF VL+W
Sbjct: 121 PKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISVIDSPGILSGEKQRISRGYDFCQVLQW 180
Query: 178 FAERVDLIILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALM 237
FAERVD IILLFDAHKL+ISDEFSEAI A RG +DKIRVVLNKAD V+TQQLMRVYGALM
Sbjct: 181 FAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALM 240
Query: 238 WALGKVVGTPEVLRVYIGSFWSQPLLVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDL 297
W+LGKV+ TPEVLRVYIGSFW+QPL DNRRLFE E QDLFRDIQ LP+ AA+RKLNDL
Sbjct: 241 WSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDL 300
Query: 298 VKRARLVRVHAYIISYLKKEMPSVFGKENKKKQLILKLPVIFAKIQLEHHISPGDFPDCQ 357
+KRARL +VHAYIISYLKKEMPSVFGKENKK++LI +LP I+ ++Q E+ IS GDFP+ +
Sbjct: 301 IKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVK 360
Query: 358 KMQELLMAHDFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEELESTEVGVQGGAFEGT 417
MQE L +DFTKFHSLKPKL+EA+D ML++ I+ LM L+ QEE + VQGGAF+GT
Sbjct: 361 AMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQEETSTPTQLVQGGAFDGT 420
Query: 418 HMGPFVERGPDEAMEDGEEGSDDEAEWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMV 477
GPF ++ +G + DE EWVV KDK YDE+FY L+P +GK+SG AK MV
Sbjct: 421 TEGPF-----NQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMV 475
Query: 478 GTKLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRR 537
+KLPNSVLG+IWKL+D D DGMLD+EEFALA HLI+ KL+G+ LP++LP LVPPS R+
Sbjct: 476 TSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRK 535
Query: 538 HKGSAE 543
A+
Sbjct: 536 SLPKAD 541
>gi|149363672 sarcalumenin [Homo sapiens]
Length = 473
Score = 213 bits (543), Expect = 3e-55
Identities = 126/389 (32%), Positives = 205/389 (52%), Gaps = 16/389 (4%)
Query: 21 VTSALKELYRTKLLPLEEHYRFGAFHSPALEDADFDGKPMVLVAGQYSTGKTSFIQYLLE 80
V L+++Y + + PLE+ Y++ + D + KPMVL G +S GK++ I YLL
Sbjct: 56 VLQRLRKIYHSSIKPLEQSYKYNELRQHEITDGEITSKPMVLFLGPWSVGKSTMINYLLG 115
Query: 81 QEVPGSRV--GPEPTTDCFVAVMHGDTEGTVPGNALVVDPDKPFRKLNPFGNTFLNRFMC 138
E ++ G EPTT F +MHG T+ G + D + F L FG FL + +
Sbjct: 116 LENTRYQLYTGAEPTTSEFTVLMHGPKLKTIEGIVMAADSARSFSPLEKFGQNFLEKLIG 175
Query: 139 AQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAERVDLIILLFDAHKLEISD 198
++P+++LE ++ +DTPGI+ KQ+ RGY F V +WF +R DLI ++FD KL++
Sbjct: 176 IEVPHKLLERVTFVDTPGIIENRKQQ-ERGYPFNDVCQWFIDRADLIFVVFDPTKLDVGL 234
Query: 199 EFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWALGKVVGTPEVLRVYIGSFW 258
E L+G E +IR++LNKAD + TQ LMRVYGAL W+L ++ E RVY+ SFW
Sbjct: 235 ELEMLFRQLKGRESQIRIILNKADNLATQMLMRVYGALFWSLAPLINVTEPPRVYVSSFW 294
Query: 259 SQPLLVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKRARLVRVHAYIIS-YLK-- 315
Q ++ LF EE L D+ + + K+ + + A VR+HA ++ YL+
Sbjct: 295 PQEYKPDTHQELFLQEEISLLEDLNQVIENRLENKIAFIRQHAIRVRIHALLVDRYLQTY 354
Query: 316 KEMPSVFGKENKKKQLILKLP---VIFAKIQLEHHISPGDFPDCQKMQELLMAHDFTKFH 372
K+ + F + I++ P IF I + ++S D P+ + ++ + + F
Sbjct: 355 KDKMTFFSDGELVFKDIVEDPDKFYIFKTILAKTNVSKFDLPNREAYKDFFGINPISSFK 414
Query: 373 SLKPK-------LLEALDEMLTHDIAKLM 394
L + LE ++ +T ++ L+
Sbjct: 415 LLSQQCSYMGGCFLEKIERAITQELPGLL 443
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 104 bits (260), Expect = 2e-22
Identities = 51/98 (52%), Positives = 69/98 (70%), Gaps = 1/98 (1%)
Query: 441 EAEWVVT-KDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDG 499
E W V +DK+KYD IF +L+P +G LSG K K ++ +KLP +LGR+W+LSD+D DG
Sbjct: 119 ELPWAVKPEDKAKYDAIFDSLSPVNGFLSGDKVKPVLLNSKLPVDILGRVWELSDIDHDG 178
Query: 500 MLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRR 537
MLD +EFA+A L+ LE +P +LP LVPPSKR+
Sbjct: 179 MLDRDEFAVAMFLVYCALEKEPVPMSLPPALVPPSKRK 216
Score = 64.7 bits (156), Expect = 2e-10
Identities = 40/96 (41%), Positives = 55/96 (57%), Gaps = 3/96 (3%)
Query: 444 WVVTK-DKSKYDEIFYNL-APADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGML 501
WVV+ +K+KYDEIF DG +SG + + + T LP+++L IW L D G L
Sbjct: 218 WVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAHIWSLCDTKDCGKL 277
Query: 502 DDEEFALASHLIEAKL-EGHGLPANLPRRLVPPSKR 536
++FALA HLI KL +G P L ++PPS R
Sbjct: 278 SKDQFALAFHLISQKLIKGIDPPHVLTPEMIPPSDR 313
Score = 44.7 bits (104), Expect = 2e-04
Identities = 22/71 (30%), Positives = 39/71 (54%)
Query: 465 GKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPA 524
G++ S A ++ + LP+ +LG+IW L+D D G+L+ +EF +A L+ G +
Sbjct: 32 GRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALRLVACAQNGLEVSL 91
Query: 525 NLPRRLVPPSK 535
+ VPP +
Sbjct: 92 SSLNLAVPPPR 102
>gi|10864047 epidermal growth factor receptor pathway substrate
15-like 1 [Homo sapiens]
Length = 864
Score = 103 bits (257), Expect = 4e-22
Identities = 50/98 (51%), Positives = 69/98 (70%), Gaps = 1/98 (1%)
Query: 441 EAEWVV-TKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDG 499
EA W V ++K+K+D IF +L P +G LSG K K ++ +KLP VLGR+W LSD+D+DG
Sbjct: 118 EAHWAVRVEEKAKFDGIFESLLPINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDG 177
Query: 500 MLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRR 537
LD +EFA+A HL+ LE +P+ LP L+PPSKR+
Sbjct: 178 HLDRDEFAVAMHLVYRALEKEPVPSALPPSLIPPSKRK 215
Score = 58.9 bits (141), Expect = 1e-08
Identities = 37/100 (37%), Positives = 55/100 (55%), Gaps = 3/100 (3%)
Query: 444 WVV-TKDKSKYDEIFYNL-APADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGML 501
WVV DK ++DEIF DG +SG + K + + L ++L IW L+D + G L
Sbjct: 269 WVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQTGKL 328
Query: 502 DDEEFALASHLIEAKL-EGHGLPANLPRRLVPPSKRRHKG 540
++FALA + I+ K+ +G P L +VPPS+R G
Sbjct: 329 SKDQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSERGTPG 368
Score = 45.8 bits (107), Expect = 1e-04
Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 1/86 (1%)
Query: 451 SKYDEIFYNLAPA-DGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLDDEEFALA 509
S Y+ + + PA G++ S+A ++ + L + +LG+IW L+D + G LD + F +A
Sbjct: 17 SLYESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVA 76
Query: 510 SHLIEAKLEGHGLPANLPRRLVPPSK 535
L+ GH + + +PP K
Sbjct: 77 LRLVACAQSGHEVTLSNLNLSMPPPK 102
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 78.2 bits (191), Expect = 2e-14
Identities = 42/98 (42%), Positives = 59/98 (60%), Gaps = 2/98 (2%)
Query: 442 AEWVVTKD-KSKYDEIFYNLAPA-DGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDG 499
AEW V + + KY ++F + G L+G +A+T ++ + LP + L IW LSD+D+DG
Sbjct: 213 AEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDG 272
Query: 500 MLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRR 537
L EEF LA HLI+ + G LP LP +PPS RR
Sbjct: 273 KLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRR 310
Score = 75.5 bits (184), Expect = 1e-13
Identities = 33/85 (38%), Positives = 59/85 (69%), Gaps = 1/85 (1%)
Query: 444 WVVT-KDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLD 502
W +T ++++K+D+ F++L P G ++G +A+ + + LP VL +IW L+D++ DG +D
Sbjct: 15 WAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMD 74
Query: 503 DEEFALASHLIEAKLEGHGLPANLP 527
EF++A LI+ KL+G+ LP+ LP
Sbjct: 75 QVEFSIAMKLIKLKLQGYQLPSALP 99
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 78.2 bits (191), Expect = 2e-14
Identities = 42/98 (42%), Positives = 59/98 (60%), Gaps = 2/98 (2%)
Query: 442 AEWVVTKD-KSKYDEIFYNLAPA-DGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDG 499
AEW V + + KY ++F + G L+G +A+T ++ + LP + L IW LSD+D+DG
Sbjct: 213 AEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDG 272
Query: 500 MLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRR 537
L EEF LA HLI+ + G LP LP +PPS RR
Sbjct: 273 KLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRR 310
Score = 75.5 bits (184), Expect = 1e-13
Identities = 33/85 (38%), Positives = 59/85 (69%), Gaps = 1/85 (1%)
Query: 444 WVVT-KDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLD 502
W +T ++++K+D+ F++L P G ++G +A+ + + LP VL +IW L+D++ DG +D
Sbjct: 15 WAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMD 74
Query: 503 DEEFALASHLIEAKLEGHGLPANLP 527
EF++A LI+ KL+G+ LP+ LP
Sbjct: 75 QVEFSIAMKLIKLKLQGYQLPSALP 99
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 77.4 bits (189), Expect = 3e-14
Identities = 36/91 (39%), Positives = 60/91 (65%), Gaps = 1/91 (1%)
Query: 444 WVVT-KDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLD 502
W +T ++++K+D F NL P+ G ++G +A+ + + + LP VL IW LSD+++DG +D
Sbjct: 16 WAITSEERTKHDRQFDNLKPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMD 75
Query: 503 DEEFALASHLIEAKLEGHGLPANLPRRLVPP 533
+EF++A LI+ KL+G LP LP + P
Sbjct: 76 QQEFSIAMKLIKLKLQGQQLPVVLPPIMKQP 106
Score = 68.9 bits (167), Expect = 1e-11
Identities = 43/108 (39%), Positives = 56/108 (51%), Gaps = 2/108 (1%)
Query: 434 GEEGSDDEAEWVVTKD-KSKYDEIFYNLAPA-DGKLSGSKAKTWMVGTKLPNSVLGRIWK 491
G +EW V + + KY + F L + G LSG +A+ ++ + L + L IW
Sbjct: 228 GNSPKTGTSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWT 287
Query: 492 LSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRRHK 539
L+DVD DG L EEF LA HL + G LP LP LVPPS R K
Sbjct: 288 LADVDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVPPSFRGGK 335
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 77.4 bits (189), Expect = 3e-14
Identities = 36/91 (39%), Positives = 60/91 (65%), Gaps = 1/91 (1%)
Query: 444 WVVT-KDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLD 502
W +T ++++K+D F NL P+ G ++G +A+ + + + LP VL IW LSD+++DG +D
Sbjct: 16 WAITSEERTKHDRQFDNLKPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMD 75
Query: 503 DEEFALASHLIEAKLEGHGLPANLPRRLVPP 533
+EF++A LI+ KL+G LP LP + P
Sbjct: 76 QQEFSIAMKLIKLKLQGQQLPVVLPPIMKQP 106
Score = 68.9 bits (167), Expect = 1e-11
Identities = 43/108 (39%), Positives = 56/108 (51%), Gaps = 2/108 (1%)
Query: 434 GEEGSDDEAEWVVTKD-KSKYDEIFYNLAPA-DGKLSGSKAKTWMVGTKLPNSVLGRIWK 491
G +EW V + + KY + F L + G LSG +A+ ++ + L + L IW
Sbjct: 228 GNSPKTGTSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWT 287
Query: 492 LSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRRHK 539
L+DVD DG L EEF LA HL + G LP LP LVPPS R K
Sbjct: 288 LADVDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVPPSFRGGK 335
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 77.4 bits (189), Expect = 3e-14
Identities = 36/91 (39%), Positives = 60/91 (65%), Gaps = 1/91 (1%)
Query: 444 WVVT-KDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLD 502
W +T ++++K+D F NL P+ G ++G +A+ + + + LP VL IW LSD+++DG +D
Sbjct: 16 WAITSEERTKHDRQFDNLKPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMD 75
Query: 503 DEEFALASHLIEAKLEGHGLPANLPRRLVPP 533
+EF++A LI+ KL+G LP LP + P
Sbjct: 76 QQEFSIAMKLIKLKLQGQQLPVVLPPIMKQP 106
Score = 68.9 bits (167), Expect = 1e-11
Identities = 43/108 (39%), Positives = 56/108 (51%), Gaps = 2/108 (1%)
Query: 434 GEEGSDDEAEWVVTKD-KSKYDEIFYNLAPA-DGKLSGSKAKTWMVGTKLPNSVLGRIWK 491
G +EW V + + KY + F L + G LSG +A+ ++ + L + L IW
Sbjct: 228 GNSPKTGTSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWT 287
Query: 492 LSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRRHK 539
L+DVD DG L EEF LA HL + G LP LP LVPPS R K
Sbjct: 288 LADVDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVPPSFRGGK 335
>gi|190886435 RALBP1 associated Eps domain containing 1 isoform a
[Homo sapiens]
Length = 795
Score = 68.6 bits (166), Expect = 1e-11
Identities = 39/105 (37%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Query: 430 AMEDGEEGSDDEAEWVVTKDKSKYD-EIFYNLAP-ADGKLSGSKAKTWMVGTKLPNSVLG 487
A+E + S + W +T ++ +Y F + P +G + GS AK + +KLP L
Sbjct: 265 AIEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELS 324
Query: 488 RIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVP 532
IW+LSD D+DG L +EF A HL+ A+ G+ LP LP L+P
Sbjct: 325 HIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMP 369
>gi|190886437 RALBP1 associated Eps domain containing 1 isoform b
[Homo sapiens]
Length = 769
Score = 68.6 bits (166), Expect = 1e-11
Identities = 39/105 (37%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Query: 430 AMEDGEEGSDDEAEWVVTKDKSKYD-EIFYNLAP-ADGKLSGSKAKTWMVGTKLPNSVLG 487
A+E + S + W +T ++ +Y F + P +G + GS AK + +KLP L
Sbjct: 265 AIEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELS 324
Query: 488 RIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVP 532
IW+LSD D+DG L +EF A HL+ A+ G+ LP LP L+P
Sbjct: 325 HIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMP 369
>gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1
[Homo sapiens]
Length = 660
Score = 61.2 bits (147), Expect = 2e-09
Identities = 64/225 (28%), Positives = 97/225 (43%), Gaps = 24/225 (10%)
Query: 311 ISYLKKEMPSVFGKENKKKQLILKLPVIFAKIQLEHHISPGDFPDCQKMQELLMAHDFTK 370
I YL E S +++ KQ + P + SP P Q + ++H ++K
Sbjct: 163 IPYLTTEKNSFKRMDDEDKQQETQSPT------MSPLASPPSSPP--HYQRVPLSHGYSK 214
Query: 371 FHSLKPKLLEALDEMLTHDIAKLMPLLRQEELESTEVGVQGGAFEGTHMGPF-VERGPDE 429
S + ++M PL++ E S G + + + + F VER
Sbjct: 215 LRS-------SAEQMHPAPYEARQPLVQPEGSSSGGPGTKPLRHQASLIRSFSVER---- 263
Query: 430 AMEDGEEGSDDEAEWVVTKDKSKYD-EIFYNLAPADGK-LSGSKAKTWMVGTKLPNSVLG 487
E + S + W +T+++ +Y F +L P +SGS AK + +KL L
Sbjct: 264 --ELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELS 321
Query: 488 RIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVP 532
IW+LSD D DG L EF A HLI A+ G+ LP LP L P
Sbjct: 322 YIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQP 366
>gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2
[Homo sapiens]
Length = 659
Score = 60.8 bits (146), Expect = 3e-09
Identities = 53/176 (30%), Positives = 81/176 (46%), Gaps = 16/176 (9%)
Query: 360 QELLMAHDFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEELESTEVGVQGGAFEGTHM 419
Q + ++H ++K S + ++M PL++ E S G + + + +
Sbjct: 203 QRVPLSHGYSKLRS-------SAEQMHPAPYEARQPLVQPEGSSSGGPGTKPLRHQASLI 255
Query: 420 GPF-VERGPDEAMEDGEEGSDDEAEWVVTKDKSKYD-EIFYNLAPADGK-LSGSKAKTWM 476
F VER E + S + W +T+++ +Y F +L P +SGS AK +
Sbjct: 256 RSFSVER------ELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFF 309
Query: 477 VGTKLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVP 532
+KL L IW+LSD D DG L EF A HLI A+ G+ LP LP L P
Sbjct: 310 TKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQP 365
>gi|4557537 developmentally regulated GTP binding protein 2 [Homo
sapiens]
Length = 364
Score = 35.8 bits (81), Expect = 0.10
Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 4/55 (7%)
Query: 148 SISIIDTPGILSGAKQRVSRGYDFPAVLRWFAERVDLIILLFDAHKLEISDEFSE 202
+I ++D PGI+ GA Q RG AV A D+II++ DA K E+ E
Sbjct: 110 NIQLLDLPGIIEGAAQGKGRGRQVIAV----ARTADVIIMMLDATKGEVQRSLLE 160
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 33.1 bits (74), Expect = 0.67
Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Query: 399 QEELESTEVGVQGGAFE-GTHMGPFVERGPDEAMEDGEEGSDDEAEWVVTKDKSKYDE-- 455
Q+E E + G +GG+ E G+ G R D A+ EG ++ + K + +E
Sbjct: 769 QQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKG 828
Query: 456 IFYN---LAPADGKLSGSKAKTWMVGTK 480
+ N L+PAD K G K++ +V TK
Sbjct: 829 VVTNGLDLSPADEKKGGDKSEEKVVVTK 856
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 33.1 bits (74), Expect = 0.67
Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Query: 399 QEELESTEVGVQGGAFE-GTHMGPFVERGPDEAMEDGEEGSDDEAEWVVTKDKSKYDE-- 455
Q+E E + G +GG+ E G+ G R D A+ EG ++ + K + +E
Sbjct: 393 QQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKG 452
Query: 456 IFYN---LAPADGKLSGSKAKTWMVGTK 480
+ N L+PAD K G K++ +V TK
Sbjct: 453 VVTNGLDLSPADEKKGGDKSEEKVVVTK 480
>gi|7661622 hypothetical protein LOC25906 [Homo sapiens]
Length = 121
Score = 32.0 bits (71), Expect = 1.5
Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 7/105 (6%)
Query: 369 TKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEELESTEVGVQGGAFEGTHMGPF----VE 424
T F SL P++ E L L + L +QE+ + +Q A + ++ P E
Sbjct: 3 TLFPSLFPRVTETLWFNLDRPCVEETELQQQEQQH--QAWLQSIAEKDNNLVPIGKPASE 60
Query: 425 RGPDEAMEDGEEGSDDEAEWVVTKDKSKYDEI-FYNLAPADGKLS 468
DE ED E+ D E + +D DE+ YN +P DG+++
Sbjct: 61 HYDDEEEEDDEDDEDSEEDSEDDEDMQDMDEMNDYNESPDDGEVN 105
>gi|40217805 nucleolar protein 9 [Homo sapiens]
Length = 702
Score = 31.2 bits (69), Expect = 2.5
Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 6/68 (8%)
Query: 54 DFDGKPMVLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGDTEGTVPGNA 113
+ DG P++LV G GK++F +YL+ + P D ++ G TE T PG
Sbjct: 295 EVDGCPVILVCGSQDVGKSTFNRYLINH-----LLNSLPCVD-YLECDLGQTEFTPPGCI 348
Query: 114 LVVDPDKP 121
+++ +P
Sbjct: 349 SLLNITEP 356
>gi|40068065 hypothetical protein LOC54058 [Homo sapiens]
Length = 322
Score = 30.8 bits (68), Expect = 3.3
Identities = 17/51 (33%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Query: 382 LDEMLTHDIAKLMPLLRQEELESTEVGVQGGAFEGTHMGPFVERGPDEAME 432
LD + +L L ++LE V+GG EG H+ P E PD+A++
Sbjct: 85 LDSSAAEQVTRLTLKLLGQKLEQERQNVEGGP-EGLHLEPGNEDRPDDALQ 134
>gi|94681049 hypothetical protein LOC80217 [Homo sapiens]
Length = 1665
Score = 30.4 bits (67), Expect = 4.3
Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 7/85 (8%)
Query: 294 LNDLVKRARLVRVHAYIISYLKKEMPSVFGKENKKKQLILKLPVIFAKIQLEHHISPGDF 353
L D++ + + V + + +Y +KE KE +++ I ++LE + +F
Sbjct: 1012 LKDIIYKVKTVFNNEFDAAYKQKEFEIARVKERN-----VRIREIILDLELEEAVWQPEF 1066
Query: 354 PDCQKMQELLMAHD--FTKFHSLKP 376
DC+K + L+ D T +KP
Sbjct: 1067 EDCEKPERTLVVQDEEITAHKHIKP 1091
>gi|22749217 coiled-coil domain containing 63 [Homo sapiens]
Length = 563
Score = 30.4 bits (67), Expect = 4.3
Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 20/118 (16%)
Query: 183 DLIILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWALGK 242
D IILL KL D S LR EDK+R +ADM E++ G+
Sbjct: 359 DEIILLRSQQKLSHDDNHS----VLRQLEDKLRKTTEEADMYESK------------YGE 402
Query: 243 VVGTPEVLRVYIGSFWSQPLLVPDNRRLFELEEQDLFRDIQGLPRHAAL--RKLNDLV 298
V T ++L+ + + + + + L +L E DI LP++ A+ +K NDL+
Sbjct: 403 VSKTLDLLKNSVEKLFKK-INCDATKILVQLGETGKVTDI-NLPQYFAIIEKKTNDLL 458
>gi|45331213 RAN binding protein 6 [Homo sapiens]
Length = 1105
Score = 30.0 bits (66), Expect = 5.6
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 4/48 (8%)
Query: 477 VGTKLPNSVLGRIW----KLSDVDRDGMLDDEEFALASHLIEAKLEGH 520
+GT+ VL I K +V DG L+DE +++AKLEGH
Sbjct: 765 IGTEPDTDVLSEIMNSFAKSIEVMGDGCLNDEHLEELGGILKAKLEGH 812
>gi|4758796 developmentally regulated GTP binding protein 1 [Homo
sapiens]
Length = 367
Score = 29.6 bits (65), Expect = 7.4
Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
Query: 149 ISIIDTPGILSGAKQRVSRGYDFPAVLRWFAERVDLIILLFDAHK 193
I ++D PGI+ GAK RG AV A +LI+++ D K
Sbjct: 113 IQLLDLPGIIEGAKDGKGRGRQVIAV----ARTCNLILIVLDVLK 153
>gi|22749443 EF-hand domain family, member A1 [Homo sapiens]
Length = 434
Score = 29.6 bits (65), Expect = 7.4
Identities = 48/228 (21%), Positives = 89/228 (39%), Gaps = 27/228 (11%)
Query: 288 HAALRKL----NDLVKRARLVRVHAYIISYLKKEMPSVFGKENKKKQLILKLPVIFAKIQ 343
H A + L N+++++ ++ I + ++ +V E ++ I+K P I +Q
Sbjct: 178 HVAFKMLDTDGNEMIEKREFFKLQKIISK--QDDLMTVKTNETGYQEAIVKEPEINTTLQ 235
Query: 344 LEHHISPGDFPDCQKMQELLMAHDFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEELE 403
+ G Q L +F +F L + EM +K + +R+E+
Sbjct: 236 MRFFGKRG--------QRKLHYKEFRRFME---NLQTEIQEMEFLQFSKGLSFMRKEDFA 284
Query: 404 STEVGVQGGAFEGTHMGPFVERGPDEAMEDGEEGSDDE----AEWVVTKDKSKYDEIFYN 459
+ F T + E + GE S DE + + ++
Sbjct: 285 EWLL-----FFTNTENKDIYWKNVREKLSAGESISLDEFKSFCHFTTHLEDFAIAMQMFS 339
Query: 460 LAPADGKLSGSK-AKTWMVGTKLPNSVLGRIWKLSDVDRDGMLDDEEF 506
LA +L+ K A G +L N++L ++K+ D+D D L EEF
Sbjct: 340 LAHRPVRLAEFKRAVKVATGQELSNNILDTVFKIFDLDGDECLSHEEF 387
>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
Length = 4753
Score = 29.3 bits (64), Expect = 9.6
Identities = 17/50 (34%), Positives = 28/50 (56%), Gaps = 9/50 (18%)
Query: 43 GAFHSPALE--------DADFDGKPMVLVAGQYSTGKTSFIQYLLEQEVP 84
G FH P+++ D G VL+AG+ +TGK++F++ L+E P
Sbjct: 2359 GTFH-PSIQTERLLYVVDLLLSGGQPVLLAGEAATGKSAFVEVLVEPHHP 2407
>gi|148664201 cytoskeleton associated protein 2 isoform 2 [Homo
sapiens]
Length = 683
Score = 29.3 bits (64), Expect = 9.6
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 6/51 (11%)
Query: 254 IGSFWSQPLLVPDNRRLFELEEQDLFRDI-----QGLPRHAALRKLNDLVK 299
+GSFW+ + D +RLF + + F + +G P+ L LNDL+K
Sbjct: 403 VGSFWTT-MAEEDEQRLFTEKVNNTFSECLNLINEGCPKEDILVTLNDLIK 452
>gi|148664244 cytoskeleton associated protein 2 isoform 1 [Homo
sapiens]
Length = 682
Score = 29.3 bits (64), Expect = 9.6
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 6/51 (11%)
Query: 254 IGSFWSQPLLVPDNRRLFELEEQDLFRDI-----QGLPRHAALRKLNDLVK 299
+GSFW+ + D +RLF + + F + +G P+ L LNDL+K
Sbjct: 402 VGSFWTT-MAEEDEQRLFTEKVNNTFSECLNLINEGCPKEDILVTLNDLIK 451
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.138 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,087,750
Number of Sequences: 37866
Number of extensions: 1041031
Number of successful extensions: 2660
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 2617
Number of HSP's gapped (non-prelim): 49
length of query: 543
length of database: 18,247,518
effective HSP length: 107
effective length of query: 436
effective length of database: 14,195,856
effective search space: 6189393216
effective search space used: 6189393216
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.