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Search of human proteins with 21312134
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21312134 mediator complex subunit 15 isoform b [Homo
sapiens]
(748 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 1501 0.0
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 1482 0.0
gi|169164663 PREDICTED: similar to mediator complex subunit 15 [... 129 1e-29
gi|221139761 zinc finger protein 853 [Homo sapiens] 127 3e-29
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 127 3e-29
gi|62953127 polyhomeotic 1-like [Homo sapiens] 126 6e-29
gi|33286444 mastermind-like 2 [Homo sapiens] 125 2e-28
gi|169164745 PREDICTED: similar to hCG2014450 [Homo sapiens] 123 7e-28
gi|169163050 PREDICTED: hypothetical protein LOC100127989 [Homo ... 123 7e-28
gi|169164311 PREDICTED: similar to hCG2014450 [Homo sapiens] 122 2e-27
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 113 7e-25
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 112 2e-24
gi|110347429 mediator complex subunit 12 [Homo sapiens] 112 2e-24
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 111 2e-24
gi|93141033 PAX interacting protein 1 [Homo sapiens] 109 8e-24
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 107 5e-23
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 107 5e-23
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 100 4e-21
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 100 6e-21
gi|226246533 TOX high mobility group box family member 3 isoform... 99 1e-20
gi|226054295 TOX high mobility group box family member 3 isoform... 99 1e-20
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 97 7e-20
gi|119943102 CREB binding protein isoform b [Homo sapiens] 95 2e-19
gi|119943104 CREB binding protein isoform a [Homo sapiens] 95 2e-19
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 95 2e-19
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 93 1e-18
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 93 1e-18
gi|56549696 E1A binding protein p400 [Homo sapiens] 92 1e-18
gi|15812226 transcriptional regulating factor 1 [Homo sapiens] 87 4e-17
gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens] 86 2e-16
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 1501 bits (3887), Expect = 0.0
Identities = 748/748 (100%), Positives = 748/748 (100%)
Query: 1 MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA
Sbjct: 1 MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
Query: 61 RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG 120
RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG
Sbjct: 61 RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG 120
Query: 121 QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQ 180
QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQ
Sbjct: 121 QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQ 180
Query: 181 QQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQR 240
QQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQR
Sbjct: 181 QQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQR 240
Query: 241 IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ 300
IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ
Sbjct: 241 IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ 300
Query: 301 PPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQ 360
PPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQ
Sbjct: 301 PPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQ 360
Query: 361 PQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQ 420
PQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQ
Sbjct: 361 PQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQ 420
Query: 421 PSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMS 480
PSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMS
Sbjct: 421 PSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMS 480
Query: 481 PAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRC 540
PAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRC
Sbjct: 481 PAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRC 540
Query: 541 PLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYR 600
PLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYR
Sbjct: 541 PLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYR 600
Query: 601 TFVPAMTAIHGPPITAPVVCTRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSN 660
TFVPAMTAIHGPPITAPVVCTRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSN
Sbjct: 601 TFVPAMTAIHGPPITAPVVCTRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSN 660
Query: 661 NGTVHLICKLDDKDLPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRL 720
NGTVHLICKLDDKDLPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRL
Sbjct: 661 NGTVHLICKLDDKDLPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRL 720
Query: 721 LQLPDKHSVTALLNTWAQSVHQACLSAA 748
LQLPDKHSVTALLNTWAQSVHQACLSAA
Sbjct: 721 LQLPDKHSVTALLNTWAQSVHQACLSAA 748
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 1482 bits (3836), Expect = 0.0
Identities = 748/788 (94%), Positives = 748/788 (94%), Gaps = 40/788 (5%)
Query: 1 MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA
Sbjct: 1 MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
Query: 61 RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG 120
RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG
Sbjct: 61 RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG 120
Query: 121 QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQ 180
QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQ
Sbjct: 121 QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQ 180
Query: 181 QQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQR 240
QQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQR
Sbjct: 181 QQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQR 240
Query: 241 IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ 300
IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ
Sbjct: 241 IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ 300
Query: 301 PPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQ 360
PPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQ
Sbjct: 301 PPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQ 360
Query: 361 PQVQQQQTAVQTAQAAQMVAPGV------------------------------------- 383
PQVQQQQTAVQTAQAAQMVAPGV
Sbjct: 361 PQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQ 420
Query: 384 ---QVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSF 440
QVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSF
Sbjct: 421 PMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSF 480
Query: 441 LPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLS 500
LPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLS
Sbjct: 481 LPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLS 540
Query: 501 KYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMA 560
KYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMA
Sbjct: 541 KYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMA 600
Query: 561 VPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGPPITAPVVC 620
VPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGPPITAPVVC
Sbjct: 601 VPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGPPITAPVVC 660
Query: 621 TRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDDKDLPSVPP 680
TRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDDKDLPSVPP
Sbjct: 661 TRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDDKDLPSVPP 720
Query: 681 LELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTALLNTWAQSV 740
LELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTALLNTWAQSV
Sbjct: 721 LELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTALLNTWAQSV 780
Query: 741 HQACLSAA 748
HQACLSAA
Sbjct: 781 HQACLSAA 788
>gi|169164663 PREDICTED: similar to mediator complex subunit 15
[Homo sapiens]
Length = 229
Score = 129 bits (323), Expect = 1e-29
Identities = 63/90 (70%), Positives = 71/90 (78%), Gaps = 10/90 (11%)
Query: 593 VFNHSLYRTFVPAMTAIHGPPIT----------APVVCTRKRRLEDDERQSIPSVLQGEV 642
+FNHSLYR F+P M AIH PPIT APVVCT+K RLEDDE+QSIPSVLQG V
Sbjct: 62 LFNHSLYRIFMPTMIAIHSPPITYIQLGWASQRAPVVCTQKHRLEDDEQQSIPSVLQGLV 121
Query: 643 ARLDPKFLVNLDPSHCSNNGTVHLICKLDD 672
ARL+PK ++NLDPSHCSNNGTV LICKL +
Sbjct: 122 ARLEPKCMINLDPSHCSNNGTVRLICKLGE 151
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 127 bits (320), Expect = 3e-29
Identities = 112/286 (39%), Positives = 143/286 (50%), Gaps = 45/286 (15%)
Query: 150 QTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQ 209
QTQ +Q LQQQ+Q QQ Q+QQ QQQ+Q QQQQ Q Q+ QQQFQ QQQ+Q
Sbjct: 178 QTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQ---QQQEQ 234
Query: 210 LQQQQQ----QQQHLIK--LHHQNQQQIQQQ---QQQLQRIAQLQLQQQQQQQQQQQQQ- 259
LQQQQQ QQQ ++ L Q Q Q+QQQ QQQ Q QL LQQQ+Q QQQQQQQ
Sbjct: 235 LQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQL 294
Query: 260 -QQQALQAQPPIQQPPMQQPQP---------PPSQALPQQLQQMHHTQHHQPPPQPQQPP 309
QQQ Q Q QPP +P+ P Q+L+Q Q + QQ
Sbjct: 295 LQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQ-- 352
Query: 310 VAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQ-------PPVQPQ 362
+ + QL Q + Q L Q + Q+ + L+ + QQ PVQP+
Sbjct: 353 --EQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPE 410
Query: 363 VQQQ--------QTAVQTAQAAQMVA-PGVQVSQS--SLPMLSSPS 397
+Q + AV A AA +VA PG V Q LP +++P+
Sbjct: 411 LQLELVPAAGGGGAAVPGAPAAVVVAPPGYVVVQELMVLPAVAAPA 456
Score = 124 bits (312), Expect = 2e-28
Identities = 98/240 (40%), Positives = 124/240 (51%), Gaps = 13/240 (5%)
Query: 150 QTQLQLQQVALQQQQQQQQFQQQQQAALQQQ---QQQQQQQQFQAQQSAMQQQFQAVVQQ 206
Q QLQ QQV QQ+ QQQQ Q Q Q A +QQ QQ+Q QQQ Q QQ QQQ Q +QQ
Sbjct: 156 QQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQ--LQQ 213
Query: 207 QQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQA 266
QQ LQQQ+Q QQ + Q Q+Q+QQQQQ L Q QLQQQ QQQQ Q QQQ Q
Sbjct: 214 QQLLQQQEQLQQQQFQ---QQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQ 270
Query: 267 QPPIQQPPMQQPQPPPSQALPQQL--QQMHHTQHHQPPPQPQQPPVAQNQPSQLPP--QS 322
Q +QQ + Q Q Q QQL QQ Q Q P P +P + +L P
Sbjct: 271 QAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLG 330
Query: 323 QTQPLVSQAQALPGQM-LYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAP 381
Q L Q Q L Q L Q + ++ + + ++ Q++QQQ ++ + + P
Sbjct: 331 SEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTP 390
Score = 114 bits (286), Expect = 3e-25
Identities = 123/381 (32%), Positives = 164/381 (43%), Gaps = 72/381 (18%)
Query: 105 GPGQSLGGMGSLGAMGQ----PMSLSGQPP-PGTSGMAPHSMAVVSTATPQTQLQLQQVA 159
GPG GS G+ Q P + P P S S T Q +LQLQQ+
Sbjct: 36 GPGPDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLE 95
Query: 160 --------------------LQQQQQQQQFQQQQQAALQQQQQQQ--------------Q 185
L+ QQQ QQ QQQ + LQQ++ Q Q
Sbjct: 96 QQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQ 155
Query: 186 QQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQ------QQQQQLQ 239
QQQ Q QQ QQ+ Q QQQ+QLQ QQ Q+Q +++ Q QQQ+Q QQQ+QLQ
Sbjct: 156 QQQLQPQQVQEQQRLQ---QQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQ 212
Query: 240 RIAQLQLQQQQQQQQQQQQQQQ-------QALQAQPPIQQPPMQQPQPPPSQALPQ---- 288
+ LQ Q+Q QQQQ QQQQ+Q LQ Q +QQ +QQ Q Q L +
Sbjct: 213 QQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQA 272
Query: 289 QLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQS-QTQPLVSQAQ-----ALPGQMLYTQ 342
QLQQ Q + Q QQ + Q Q QL Q Q PL + + L L ++
Sbjct: 273 QLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSE 332
Query: 343 PPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPM------LSSP 396
L+ R + QQ ++ Q +Q+Q ++ + Q + ++ Q L L+
Sbjct: 333 QELEQQRQELERQQ-ELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPV 391
Query: 397 SPGQQVQTPQSMPPPPQPSPQ 417
G Q Q Q P QP Q
Sbjct: 392 ELGAQQQEVQLELTPVQPELQ 412
Score = 92.0 bits (227), Expect = 2e-18
Identities = 97/335 (28%), Positives = 139/335 (41%), Gaps = 66/335 (19%)
Query: 128 QPPPGTSGMAPHSMAVVSTATPQTQLQLQQ----------------VALQQQQQQQQFQQ 171
QP PG G+ +T T +LQ + + ++++ Q++
Sbjct: 4 QPTPGNRGLTARMEVGPATETFVLELQCLEDGGPGPDTLSGGSGGSESQEEEEPQERNSS 63
Query: 172 QQQAALQQ--------QQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKL 223
Q+ A+ ++ + Q++ Q QQ Q + QQQ Q +Q QQ Q HL +L
Sbjct: 64 PQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPE----PQQQPQHEQLQQPQPHL-EL 118
Query: 224 HHQNQQQIQQQQQQLQR------------------IAQLQLQQQQQQQQQQQQQQQQALQ 265
Q QQ QQQ QLQ+ Q QLQ QQ Q+QQ+ QQQQ+ LQ
Sbjct: 119 QQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQ 178
Query: 266 AQPPIQQPPMQQPQPPPSQALPQQL--QQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQ 323
Q +Q +QQ + Q QQL QQ Q Q Q +Q Q Q Q Q Q
Sbjct: 179 TQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQ 238
Query: 324 TQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQ-VQQQQTAVQTAQAAQMVAPG 382
Q L+ Q Q Q L Q + + + QQ +Q Q + QQQ +Q Q Q+
Sbjct: 239 QQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQL---- 294
Query: 383 VQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQ 417
+Q Q +Q+Q Q PPP +P +
Sbjct: 295 LQQQQ------------EQLQQQQLQPPPLEPEEE 317
Score = 50.4 bits (119), Expect = 6e-06
Identities = 50/188 (26%), Positives = 79/188 (42%), Gaps = 16/188 (8%)
Query: 247 QQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ 306
Q++++ Q++ Q+ A+ A P+ + + P + L QLQQ+ Q +P QPQ
Sbjct: 52 QEEEEPQERNSSPQRPAVSA--PVGASEIAEETRPGQREL--QLQQLE--QQPEPQQQPQ 105
Query: 307 QPPVAQNQPS---QLPPQSQTQPLVSQAQALPGQMLYTQ---PPLKFVRAPMVVQQPPVQ 360
+ Q QP Q PQ Q +SQ Q Q ++ Q P L+ + +Q VQ
Sbjct: 106 HEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQ 165
Query: 361 PQV----QQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSP 416
Q QQ+Q Q AQ Q++ Q+ Q +Q+Q Q + Q
Sbjct: 166 EQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQ 225
Query: 417 QPGQPSSQ 424
Q Q +
Sbjct: 226 QQFQQQQE 233
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 127 bits (320), Expect = 3e-29
Identities = 145/468 (30%), Positives = 183/468 (39%), Gaps = 109/468 (23%)
Query: 102 PPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQ---- 157
PP+GP LG Q L Q P PH +++ + + QL Q
Sbjct: 3794 PPQGPQGMLGP-------AQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQG 3846
Query: 158 ------VALQQQQQQQQFQQQ-QQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQL 210
V QQQQQQQQ QQQ A L QQ Q + SA +QQQQQL
Sbjct: 3847 LMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQL 3906
Query: 211 QQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPI 270
QQQQQ QQ Q QQQ+QQQQQ LQQQQ QQQQQQQQ QQ Q Q
Sbjct: 3907 QQQQQLQQ-------QQQQQLQQQQQ---------LQQQQLQQQQQQQQLQQQQQQQLQQ 3950
Query: 271 QQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQ 330
QQ +QQ Q Q QQ QQ QQ + + L PQ Q Q V+
Sbjct: 3951 QQQQLQQQQQQQQQQFQQQQQQ-------------QQMGLLNQSRTLLSPQQQQQQQVAL 3997
Query: 331 AQALPGQMLYTQPPLKFVRAPMVV---------QQPPVQPQVQQQQT-----------AV 370
+P + PL+ +P + +Q V P V + T A+
Sbjct: 3998 GPGMPAK------PLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAI 4051
Query: 371 QTAQAAQMVAPG---VQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPS----- 422
T + PG +S S +L P P Q + Q PP P Q Q S
Sbjct: 4052 GTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTA 4111
Query: 423 -SQPNSNVSSGPAPSPSSFLPSPSPQPS-----------------QSPVTARTPQNFSVP 464
+ + SG + S +S +P QPS Q P+ R QN + P
Sbjct: 4112 GGGSHGQLGSG-SSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGP 4170
Query: 465 SPGPLNTPVNPS-------SVMSPAGSSQAEEQQYLDKLKQLSKYIEP 505
P P PV S +M G +A+ Q L K QL +++ P
Sbjct: 4171 QP-PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQL-RHLSP 4216
Score = 70.9 bits (172), Expect = 4e-12
Identities = 93/367 (25%), Positives = 140/367 (38%), Gaps = 69/367 (18%)
Query: 86 QSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVS 145
Q L+GGP++ G G + G P PP G+ +
Sbjct: 3460 QRLSGGPSSDLQN---------HVAAGSGQERSAGDPSQPRPNPPTFAQGVINEADQRQY 3510
Query: 146 TATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQ 205
QL Q+ L+ ++Q ++ + AL +Q+ ++ + + A ++ + V +
Sbjct: 3511 EEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPE-ADAEKLKLVTE 3569
Query: 206 QQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQ-QAL 264
QQ ++Q+Q Q + +QQ++ +A+ + +QQQQQQQQQQQQQQ A+
Sbjct: 3570 QQSKIQKQLDQVR-------------KQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAV 3616
Query: 265 QAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQT 324
A P Q P + LP QL H Q Q PP Q + P
Sbjct: 3617 LALSPSQSPRL-------LTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPG 3669
Query: 325 QPLVSQAQA---------------------LPGQM----------LYTQPPLKFVRAPMV 353
P ++ A A PG + L + L+ + M
Sbjct: 3670 GPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQ 3729
Query: 354 VQQPPVQPQVQQQQTAVQTAQAA----QMVAPGVQVSQSSLPM---LSSPSPGQQVQTPQ 406
+ Q Q Q QQQQ Q A Q PGVQ +Q+ P L PS Q + Q
Sbjct: 3730 LAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQ 3789
Query: 407 SMPPPPQ 413
P PPQ
Sbjct: 3790 LSPQPPQ 3796
Score = 68.6 bits (166), Expect = 2e-11
Identities = 64/229 (27%), Positives = 95/229 (41%), Gaps = 25/229 (10%)
Query: 267 QPPIQQPPMQQPQPPPSQALP-QQLQQMHHTQHHQPPPQP--QQPPVAQNQPSQLPPQSQ 323
+ P+ PP + P PP ++ P L++ + + PP P + P + S L P +
Sbjct: 491 ESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFE 550
Query: 324 TQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGV 383
PL + LP T PP + R ++ P+ P +++ + A + P
Sbjct: 551 ESPLSPPPEELP-----TSPPPEASRLSPPPEESPMSPP--PEESPMSPPPEASRLFPPF 603
Query: 384 QVSQSSLPMLSSP-SPGQQVQTPQSMPPPPQPSPQPGQPSSQPNS---NVSS-GPAPSPS 438
+ S S P SP SP + + PPP+ SP P P S VS P P S
Sbjct: 604 EESPLSPPPEESPLSPPPEASR---LSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS 660
Query: 439 SFLPSP-----SPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPA 482
P P SP P +SP + P S SP P ++P +P SPA
Sbjct: 661 RLSPPPEESPLSPPPEESPTS--PPPEASRLSPPPEDSPTSPPPEDSPA 707
Score = 65.9 bits (159), Expect = 1e-10
Identities = 70/266 (26%), Positives = 103/266 (38%), Gaps = 40/266 (15%)
Query: 255 QQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQ--PPVAQ 312
Q + Q + L + P+ PP + P PP + P PPP+ + PP +
Sbjct: 425 QLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPT-----------SPPPEASRLSPPPEE 473
Query: 313 NQPSQLPPQSQ-TQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQ 371
S LP ++PL + P + PP + + + P P+ A++
Sbjct: 474 LPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALE 533
Query: 372 TAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMP-------PPPQPSPQPGQPSSQ 424
T ++P + S S P SP + P S P PPP+ SP P
Sbjct: 534 TP-----LSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEES 588
Query: 425 PNSNVSSGPAPSPSSFLP----SP-SPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVM 479
P S P P S P SP SP P +SP++ P S SP P ++P++P
Sbjct: 589 PMS-----PPPEASRLFPPFEESPLSPPPEESPLS--PPPEASRLSPPPEDSPMSPPPEE 641
Query: 480 SPAGSSQAEEQQYLDKLKQLSKYIEP 505
SP S E L L +S+ P
Sbjct: 642 SP--MSPPPEVSRLSPLPVVSRLSPP 665
Score = 61.6 bits (148), Expect = 3e-09
Identities = 147/620 (23%), Positives = 216/620 (34%), Gaps = 147/620 (23%)
Query: 90 GGPAAGAAGIGMPPRG----PGQ---SLGGMGSL-----GAMGQPMSLSGQPPPGTSGMA 137
GGP A IG P PG+ SL G L QP SL QPP G
Sbjct: 4046 GGPLA----IGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQ 4101
Query: 138 PHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQ 197
++++ TA + QL + + Q +L Q Q QQ ++
Sbjct: 4102 QQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLE 4161
Query: 198 QQFQ-----------AVVQQQQQLQ---------QQQQQQQHLIKLHHQNQQQIQQQQQQ 237
+ Q V+Q Q L Q + Q Q ++ + Q + QQQQQ
Sbjct: 4162 RPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQ 4221
Query: 238 LQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQP-----PMQ-----QPQP---PPSQ 284
LQ + Q+Q QQ QA++ PP Q+P P+Q QPQ P Q
Sbjct: 4222 LQALLM-----------QRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQ 4270
Query: 285 ALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVS-QAQALPGQMLYTQP 343
P LQ++ Q PP+ PP A + L P T P S Q P Q+
Sbjct: 4271 TGP--LQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQL----- 4323
Query: 344 PLKFVRAPMVVQQPPVQPQVQQQQTAV------QTAQAAQMVA------------PGVQV 385
P + P Q PP P + Q + + AA +A P +
Sbjct: 4324 PSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNL 4383
Query: 386 SQSSLPMLSSPSP-------GQQVQTPQSMPPPPQPSPQP---GQPSSQPNSNVSSGPAP 435
+++ P SS P GQ V + +P +P G S + +N AP
Sbjct: 4384 AETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAP 4443
Query: 436 SPSSFLPSPSPQPS------QSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQ--- 486
S+ L P+ Q + A+ Q + L +N AG Q
Sbjct: 4444 GTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQ 4503
Query: 487 ---------AEEQQYLDKLKQLSKYIEPL---RRMINKID---KNEDRKKDLSKMKSLLD 531
A + K K++ K + L R+ + K D +E K L + SLL
Sbjct: 4504 GTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLP 4563
Query: 532 ILTDPS------------KRCPLKTLQKCEIALEK--------------LKNDMAVPTPP 565
LT+P+ CP+ + A KN+++ P P
Sbjct: 4564 -LTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTP 4622
Query: 566 PPPVPPTKQQYLCQPLLDAV 585
P +PPT + Q +++ V
Sbjct: 4623 PSSLPPTPPPSVQQKMVNGV 4642
Score = 57.0 bits (136), Expect = 6e-08
Identities = 58/230 (25%), Positives = 84/230 (36%), Gaps = 40/230 (17%)
Query: 268 PPIQQPP---MQQPQPPPSQALPQQLQQMHHTQHHQPPPQ--PQQPPVAQNQPSQLPPQS 322
PP + PP ++ P PP +A P L PPP+ P PP ++ S P +S
Sbjct: 522 PPEESPPSPALETPLSPPPEASP--LSPPFEESPLSPPPEELPTSPPPEASRLSPPPEES 579
Query: 323 QTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPG 382
P P + PP + R ++ P+ P +++ + A ++P
Sbjct: 580 PMSP--------PPEESPMSPPPEASRLFPPFEESPLSPP--PEESPLSPPPEASRLSPP 629
Query: 383 VQVSQSSLPMLSSP-SPGQQVQTPQSMP------PPPQPSPQPGQPSSQPNSNVSSGPAP 435
+ S S P SP SP +V +P PPP+ SP P P S P P
Sbjct: 630 PEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTS-----PPP 684
Query: 436 SPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSS 485
S P P P+ P P P + P S + P S
Sbjct: 685 EASRLSPPPEDSPTSPP-----------PEDSPASPPPEDSLMSLPLEES 723
Score = 56.6 bits (135), Expect = 8e-08
Identities = 62/258 (24%), Positives = 101/258 (39%), Gaps = 34/258 (13%)
Query: 243 QLQLQQQQQQQQQQQQQQQQALQAQP------PIQQPPMQQPQPPPSQALPQQLQQMHHT 296
+L L Q ++ ++ L QP P + P P+P S P+ +
Sbjct: 803 ELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSP 862
Query: 297 QHHQPPPQPQQPPVAQNQPSQLPP-QSQTQPLVSQ-AQALPGQMLYTQPPLKFVRAPMVV 354
+ +PP +P Q P + P PP + PL+ + A + PG+ + P + +P
Sbjct: 863 RPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPS-- 920
Query: 355 QQPPVQPQVQQQQ------TAVQTAQAAQMVAPGVQV-------------SQSSLPMLS- 394
+P + PQ+ + + TA A ++P ++ S + P+L
Sbjct: 921 GEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILET 980
Query: 395 --SPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSP 452
SP P P+ +PP P P PG P P S + P P S L S P SP
Sbjct: 981 PISPPPEANCTDPEPVPPMILP-PSPGSPVG-PASPILMEPLPPQCSPLLQHSLVPQNSP 1038
Query: 453 VTARTPQNFSVPSPGPLN 470
+ +P + P PL+
Sbjct: 1039 PSQCSPPALPLSVPSPLS 1056
Score = 55.5 bits (132), Expect = 2e-07
Identities = 51/204 (25%), Positives = 82/204 (40%), Gaps = 11/204 (5%)
Query: 267 QPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ--PQQPPVAQNQPSQLPPQSQT 324
+ P+ PP + P PP +A +L PPP+ P PP ++ S P S
Sbjct: 578 ESPMSPPPEESPMSPPPEA--SRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPM 635
Query: 325 QPLVSQAQALPGQMLYTQPPLKFV-RAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGV 383
P ++ P + PL V R ++ P+ P ++ T+ A ++P
Sbjct: 636 SPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTS--PPPEASRLSPPP 693
Query: 384 QVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPS-PQPGQPSSQPNSNVSSGPAPSPSSFLP 442
+ S +S P SP+ + S+P P P P +P P S GP SP P
Sbjct: 694 EDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSE---GPHLSPRPEEP 750
Query: 443 SPSPQPSQSPVTARTPQNFSVPSP 466
SP+P + ++ + + P P
Sbjct: 751 HLSPRPEEPHLSPQAEEPHLSPQP 774
Score = 55.5 bits (132), Expect = 2e-07
Identities = 66/257 (25%), Positives = 103/257 (40%), Gaps = 54/257 (21%)
Query: 231 IQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQL 290
++ ++++LQ+ QL Q Q QQQQQQQQQ L A P Q + PS A QQ
Sbjct: 3253 LEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQ 3312
Query: 291 QQMHHTQHHQP----PPQPQQPP-------------VAQNQ----------PSQLPPQSQ 323
+ QP P P QPP + NQ + L PQ
Sbjct: 3313 LSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQS 3372
Query: 324 TQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQ----PQVQQQQTAVQ-----TAQ 374
+QP++SQ + + T PP ++ + Q + P + A + A+
Sbjct: 3373 SQPVLSQ------KPMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAK 3426
Query: 375 AAQMVAPGVQ--VSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSG 432
A + G++ ++Q S+ + +PG Q + G PSS ++V++G
Sbjct: 3427 AKMVALKGIKKVMAQGSIGV----APGMNRQQVSLL-----AQRLSGGPSSDLQNHVAAG 3477
Query: 433 PAPSPSSFLPS-PSPQP 448
S+ PS P P P
Sbjct: 3478 SGQERSAGDPSQPRPNP 3494
Score = 52.8 bits (125), Expect = 1e-06
Identities = 58/223 (26%), Positives = 88/223 (39%), Gaps = 21/223 (9%)
Query: 267 QPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ--PQQPPVAQNQPSQLPPQSQT 324
+ P+ PP + P PP +A +L PPP+ P PP + S +S
Sbjct: 668 ESPLSPPPEESPTSPPPEA--SRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPL 725
Query: 325 QPLVSQAQALP---GQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAP 381
PL + Q P G L +P + ++P + PQ ++ + Q + P
Sbjct: 726 LPLPEEPQLCPRSEGPHLSPRPEEPHLSPRP--EEPHLSPQAEEPHLSPQPEEPCLCAVP 783
Query: 382 GVQ--VSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSS 439
Q+ P LS P P + +PQ+ P P P+ S QP + SP S
Sbjct: 784 EEPHLSPQAEGPHLS-PQPEELHLSPQTEEPHLSPVPEEPCLSPQPEES-----HLSPQS 837
Query: 440 FLPSPSPQPSQSPVTARTPQNFSVP-SPGPLNTPVNPSSVMSP 481
P SP+P +S + +P+ P SP P P P +P
Sbjct: 838 EEPCLSPRPEESHL---SPELEKPPLSPRPEKPPEEPGQCPAP 877
Score = 51.6 bits (122), Expect = 3e-06
Identities = 85/353 (24%), Positives = 116/353 (32%), Gaps = 69/353 (19%)
Query: 89 TGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTAT 148
TGGP A P GPG S + ++L G P + ++V++
Sbjct: 3188 TGGPPAHLL-TPSPLSGPGGS-SLLEKFELESGALTLPGGPAASGDELDKMESSLVASEL 3245
Query: 149 PQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQ 208
P L + ++ Q++QQ Q Q A QQQQQQQQ A A
Sbjct: 3246 PLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPA------------- 3292
Query: 209 QLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQP 268
Q + H + + QQQL L L A QP
Sbjct: 3293 ---------QAMSLPHEGSSPSLAGSQQQL----SLGL----------------AGARQP 3323
Query: 269 PIQQPPMQQPQPPPSQALPQQ--------------LQQMHHTQHHQPPPQPQQPPVAQNQ 314
+ QP M P PP+ AL Q+ L H Q P Q QP ++Q
Sbjct: 3324 GLPQPLM--PTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKP 3381
Query: 315 PSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQ 374
+PP +P Q + L A ++ V + AQ
Sbjct: 3382 MGTMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQ 3441
Query: 375 AAQMVAPGVQVSQ-SSLPMLSSPSPGQQVQT--------PQSMPPPPQPSPQP 418
+ VAPG+ Q S L S P +Q +S P QP P P
Sbjct: 3442 GSIGVAPGMNRQQVSLLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRPNP 3494
Score = 50.1 bits (118), Expect = 8e-06
Identities = 56/193 (29%), Positives = 85/193 (44%), Gaps = 28/193 (14%)
Query: 304 QPQQPPVAQNQPSQLPP-QSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVV--QQPPVQ 360
QP+ V QP + P Q + +PL L Q+ + PL P++ ++ P+
Sbjct: 395 QPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQL---EAPLN-EEMPLLPPPEESPLS 450
Query: 361 PQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPM---LSSPSPGQQVQTPQSMPPPPQPSPQ 417
P ++ T+ +A+++ P ++ S LP LS P ++P S PPP+ SP
Sbjct: 451 PPPEESPTS-PPPEASRLSPPPEELPASPLPEALHLSRPLE----ESPLS--PPPEESPL 503
Query: 418 PGQPSSQPNSNVSSGPAPSPSSFLPSP------SPQPSQSPVTARTPQNFSVPSPGPLNT 471
P S P S + P P PSP SP P SP++ P S SP P
Sbjct: 504 SPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLS--PPFEESPLSPPPEEL 561
Query: 472 PVNP---SSVMSP 481
P +P +S +SP
Sbjct: 562 PTSPPPEASRLSP 574
Score = 49.3 bits (116), Expect = 1e-05
Identities = 59/231 (25%), Positives = 85/231 (36%), Gaps = 34/231 (14%)
Query: 262 QALQAQPPIQQPPMQQPQPPPSQAL-------PQQLQQMHHTQHH-QPPPQPQQPPVAQN 313
+A Q +P ++ +PPP+QAL P + +T + QPP P+ P
Sbjct: 2334 RASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPE 2393
Query: 314 QPSQLPPQSQTQPLVSQAQALPGQMLYTQPPL--------KFVRAPMV--------VQQP 357
LPP+S S+ A P +Q PL F +P+ +P
Sbjct: 2394 SCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRP 2453
Query: 358 PVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQ 417
P +PQ + + Q P V SL S + G P ++P P
Sbjct: 2454 PSRPQSRDPFAPLHKPPRPQ--PPEVAFKAGSLAHTSLGAGG----FPAALPAGPAGELH 2507
Query: 418 PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQ-NFSVPSPG 467
PS QP + V S P +F+ +PSP P P VP PG
Sbjct: 2508 AKVPSGQPPNFVRS---PGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPG 2555
Score = 47.4 bits (111), Expect = 5e-05
Identities = 67/287 (23%), Positives = 110/287 (38%), Gaps = 58/287 (20%)
Query: 233 QQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQ---QPQPPPSQALPQQ 289
++Q+Q QR+ +L ++QQ Q+ +Q+++ A A PP +P P + L +
Sbjct: 2678 EKQRQRQRLRELLIRQQIQRNTLRQEKETAA--AAAGAVGPPGSWGAEPSSPAFEQLSRG 2735
Query: 290 LQQMHHTQHHQP----PPQPQQPPV-------AQNQPSQLPPQSQTQPLVSQAQALPG-- 336
TQ PP P+ + ++ S+ PP + + ++ L G
Sbjct: 2736 QTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGS 2795
Query: 337 QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV----APGVQVSQSSLPM 392
Q Y + P + +QQ Q QQQ TA + + A PG ++ + +
Sbjct: 2796 QAFYQRAPYP---GSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQA--- 2849
Query: 393 LSSPSPGQQVQTPQSMPPPPQPSPQPGQPSS--QPNSNVSSGPAPSPSSFLPSPSPQPSQ 450
L SP G + +P P +P P P P+ + NV G P + P P P Q
Sbjct: 2850 LGSPLAGISTR----LPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGT---PFPGQGPPQ 2902
Query: 451 SP---------------------VTARTPQNFSVPSPGPLNTPVNPS 476
P V+ PQ S P LN ++P+
Sbjct: 2903 RPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPT 2949
Score = 39.7 bits (91), Expect = 0.010
Identities = 59/248 (23%), Positives = 91/248 (36%), Gaps = 20/248 (8%)
Query: 99 IGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGT-SGMAPHSMAVVSTATPQTQLQLQQ 157
+G+PP + G GS + + LS PPP T S M +S +V + Q
Sbjct: 2749 VGLPPSKLSGPILGPGSFPSDDR---LSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYP 2805
Query: 158 VALQQQQQQQQFQQQQQAALQQQQQQQQQQQF----------QAQQSAMQQQFQAVVQQQ 207
+L QQQQQQ QQQQA + +F QA S + +
Sbjct: 2806 GSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPG 2865
Query: 208 QQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQ 267
+ + Q I+L H Q+ + Q + + + + L+
Sbjct: 2866 EPVPGPAGPAQ-FIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGL 2924
Query: 268 PPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPL 327
PP Q+P PP+ P+ +H T H + P P + N+P + PL
Sbjct: 2925 AVSGLPP-QKPSAPPA---PELNNSLHPTPHTKGPTLPTGLELV-NRPPSSTELGRPNPL 2979
Query: 328 VSQAQALP 335
+A LP
Sbjct: 2980 ALEAGKLP 2987
Score = 38.9 bits (89), Expect = 0.018
Identities = 54/194 (27%), Positives = 70/194 (36%), Gaps = 37/194 (19%)
Query: 301 PPP--------QPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPM 352
PPP + ++ + + PS PP S L G L T K AP+
Sbjct: 2275 PPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFK---APL 2331
Query: 353 VVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPP 412
+ V+PQ Q AQ +AP S S P + P T PP
Sbjct: 2332 TPRASQVEPQSPGLGLRPQEPPPAQALAP----SPPSHPDIFRPGS----YTDPYAQPPL 2383
Query: 413 QPSPQPGQPS-----------SQPNSNVSSGPAPSPSSFLP-SPSPQPSQ----SPVTAR 456
P PQP P S P S V + P SS P +P P ++ SPVT R
Sbjct: 2384 TPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPR 2443
Query: 457 --TPQNFSVPSPGP 468
+P +S P P
Sbjct: 2444 FQSPDPYSRPPSRP 2457
Score = 38.5 bits (88), Expect = 0.023
Identities = 45/220 (20%), Positives = 77/220 (35%), Gaps = 41/220 (18%)
Query: 268 PPIQQPPMQQPQPPPSQALPQQLQ-----QMHHTQHHQPP---PQPQQPPVAQNQPSQLP 319
P + +P + +P PP LP++L + + PP P P P + P L
Sbjct: 893 PLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALS 952
Query: 320 PQSQTQ-PLVSQAQALPGQMLYT---QPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQA 375
P + + P ++ + P L + P+ PV P + A
Sbjct: 953 PLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPA 1012
Query: 376 AQMVAPGVQ------VSQSSLPMLSSPSPGQQVQTPQSMPPPPQPS-------------- 415
+ ++ + + S +P S PS P S+P P P
Sbjct: 1013 SPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHE 1072
Query: 416 ------PQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPS 449
+P P+ +P++ + P PSP L P+P P+
Sbjct: 1073 METEKVSEPECPALEPSA---TSPLPSPMGDLSCPAPSPA 1109
Score = 37.0 bits (84), Expect = 0.067
Identities = 49/221 (22%), Positives = 80/221 (36%), Gaps = 40/221 (18%)
Query: 265 QAQPPIQQPPMQQP----QPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPP 320
Q PP PP P PP+ + +L+ + P P P+ + S P
Sbjct: 928 QLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPE 987
Query: 321 QSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQP--PVQPQVQQQQTAVQTAQAAQM 378
+ T P + +P +L P A ++ +P P + Q Q + +Q
Sbjct: 988 ANCTDP-----EPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQC 1042
Query: 379 VAPGVQVSQSSLPM--------LSSPSPGQQVQTPQ-SMPPPPQPSPQPGQPSSQPNSNV 429
P + +S S P+ +S + +++T + S P P P P P ++
Sbjct: 1043 SPPALPLSVPS-PLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDL 1101
Query: 430 SSGPAPSPSSFL------------------PSPSPQPSQSP 452
S PAPSP+ L P P+P Q+P
Sbjct: 1102 SC-PAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTP 1141
Score = 37.0 bits (84), Expect = 0.067
Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 1/78 (1%)
Query: 383 VQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQ-PGQPSSQPNSNVSSGPAPSPSSFL 441
+ V Q S P PSP P PP +P + P +P ++P A SP S
Sbjct: 4901 LDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESAR 4960
Query: 442 PSPSPQPSQSPVTARTPQ 459
P P +P + +R P+
Sbjct: 4961 PKPRARPPEEGEDSRPPR 4978
Score = 36.6 bits (83), Expect = 0.087
Identities = 32/133 (24%), Positives = 51/133 (38%), Gaps = 9/133 (6%)
Query: 410 PPPQPSPQPGQPSSQPNSNVSS-------GPAPSPSSFLPSPSPQPSQSPVTARTPQNFS 462
P P+P Q + N +V P+P PS PSP+ P++ V T
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAE 4943
Query: 463 VPSPGPLNTPVNPSSVMSPAGSSQAE--EQQYLDKLKQLSKYIEPLRRMINKIDKNEDRK 520
P P PL +P S + E E +LK+ R++ I K R+
Sbjct: 4944 PPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWKGVRWKRLRLLLTIQKGSGRQ 5003
Query: 521 KDLSKMKSLLDIL 533
+D ++ ++ L
Sbjct: 5004 EDEREVAEFMEQL 5016
Score = 36.2 bits (82), Expect = 0.11
Identities = 70/382 (18%), Positives = 123/382 (32%), Gaps = 30/382 (7%)
Query: 120 GQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQ----- 174
G+P S P G+ G P + +T L Q +LQ+ ++ ++ Q
Sbjct: 1967 GEPDS----PWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVL 2022
Query: 175 -AALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQ 233
A + +Q + ++ + + ++ V + Q+ + ++ Q+Q +
Sbjct: 2023 YANINFPNLKQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAES 2082
Query: 234 QQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQM 293
Q + ++ + + + + Q AL + PP P + P L
Sbjct: 2083 QINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGF 2142
Query: 294 HHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMV 353
P + P Q+P Q +Q A A P + + P + P
Sbjct: 2143 LKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSP 2202
Query: 354 VQQPPVQPQVQQQQTAVQTAQAAQM--VAPGVQVSQSSLP-------------MLSSPSP 398
P QP + + Q + PG Q S P + SP
Sbjct: 2203 TGAP-AQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESP 2261
Query: 399 GQ---QVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTA 455
G + P PPP S + + + S P F+ SPS +
Sbjct: 2262 GVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLEL 2321
Query: 456 RTPQNFSVPSPGPLNTPVNPSS 477
+TP F P P + V P S
Sbjct: 2322 KTPDVFKAPLT-PRASQVEPQS 2342
Score = 36.2 bits (82), Expect = 0.11
Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 6/71 (8%)
Query: 407 SMPPPPQPSPQPG----QPSSQPNSNVSSGPAPSPSSFLPSPSPQP-SQSPVTARTPQNF 461
S PPP +PSP P P+S P + P P + P PSP P + SP +AR
Sbjct: 4907 SAPPPEEPSPPPSPLAPSPASPPTEPLVELPT-EPLAEPPVPSPLPLASSPESARPKPRA 4965
Query: 462 SVPSPGPLNTP 472
P G + P
Sbjct: 4966 RPPEEGEDSRP 4976
Score = 34.3 bits (77), Expect = 0.43
Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 9/84 (10%)
Query: 278 PQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQ 337
P+PP + + + Q PPP+ PP + PS P T+PLV LP +
Sbjct: 4886 PEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPS--PASPPTEPLVE----LPTE 4939
Query: 338 MLYTQP---PLKFVRAPMVVQQPP 358
L P PL +P + P
Sbjct: 4940 PLAEPPVPSPLPLASSPESARPKP 4963
Score = 33.5 bits (75), Expect = 0.74
Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 6/72 (8%)
Query: 385 VSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQ-PNSNVSSGPAPSPSSFLPS 443
VS + LS+P P + +P P P P+ P +P + P ++ P PSP S
Sbjct: 4898 VSNLDVRQLSAPPPEEP--SPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASS 4955
Query: 444 PS---PQPSQSP 452
P P+P P
Sbjct: 4956 PESARPKPRARP 4967
Score = 31.2 bits (69), Expect = 3.7
Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 4/66 (6%)
Query: 270 IQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVS 329
+ PP ++P PPPS P P +PPV PS LP S +
Sbjct: 4906 LSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPV----PSPLPLASSPESARP 4961
Query: 330 QAQALP 335
+ +A P
Sbjct: 4962 KPRARP 4967
>gi|62953127 polyhomeotic 1-like [Homo sapiens]
Length = 1004
Score = 126 bits (317), Expect = 6e-29
Identities = 139/514 (27%), Positives = 206/514 (40%), Gaps = 89/514 (17%)
Query: 86 QSLTGGPAAGAAGIGMP----PRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSM 141
QSL A G +G +P P G GQ+ GG+G L + G M P GT + P
Sbjct: 260 QSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSG--MGGGSCPRKGTGVVQPLPA 317
Query: 142 AVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQ 201
A T + +Q + + A ++ + QQ L + Q + + Q Q
Sbjct: 318 AQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQPH 377
Query: 202 AVVQQQQQLQQQQQQQ--QHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQ 259
+++QQQQQ+ QQ+Q Q I +HHQ QQ Q +Q QL A QQQQQQQQQQQ
Sbjct: 378 SLIQQQQQIHLQQKQVVIQQQIAIHHQ--QQFQHRQSQLLHTATHLQLAQQQQQQQQQQQ 435
Query: 260 QQQALQAQPPIQQPPMQQPQPPPSQAL-PQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQL 318
QQQ QA + P Q PQ PP+Q + P Q QQ T Q P+ Q+ P L
Sbjct: 436 QQQQPQA-TTLTAP--QPPQVPPTQQVPPSQSQQQAQTLVVQ--------PMLQSSPLSL 484
Query: 319 PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMV-------VQQPPVQPQVQQQQTAVQ 371
PP + +P + + ++PP+ ++ P + QQPP P + Q +
Sbjct: 485 PPDAAPKPPIP---------IQSKPPVAPIKPPQLGAAKMSAAQQPP--PHIPVQVVGTR 533
Query: 372 TAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSS 431
AQ A G+ +++P T + MP Q S Q SS P+S
Sbjct: 534 QPGTAQAQALGLAQLAAAVP------------TSRGMPGTVQ-SGQAHLASSPPSSQAPG 580
Query: 432 GPAPSPSSFLPSPSPQPSQ-------------SPVTARTPQNFSVPSPGPLNTPVNPSSV 478
P + P + P Q SPV A+ P F + S ++ P P ++
Sbjct: 581 ALQECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQS---VHLPGKPQTL 637
Query: 479 MSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSK 538
A +A+ ++ D + L + + + K D K L +
Sbjct: 638 ---AVKRKADSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGE------------- 681
Query: 539 RCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPT 572
K + +++ TP P PPT
Sbjct: 682 ----KAESVANVNANTPSSELVALTPAPSVPPPT 711
Score = 42.7 bits (99), Expect = 0.001
Identities = 98/445 (22%), Positives = 150/445 (33%), Gaps = 52/445 (11%)
Query: 171 QQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQ---QQLQQQQQQQQHLIKLHHQ- 226
Q Q +L ++Q Q Q Q Q +A Q Q ++QQQ QL QQ I Q
Sbjct: 25 QIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQATIAASRQA 84
Query: 227 ---NQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP- 282
N QQQ Q A + L Q + Q + A Q + PP
Sbjct: 85 SSPNTSTTQQQTTTTQ--ASINLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPL 142
Query: 283 --SQAL----PQ--QLQQMHHTQHHQPP--------PQPQQPPVAQNQPSQLPPQSQTQP 326
SQA PQ L Q++ T P P V Q PS P
Sbjct: 143 NQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADA 202
Query: 327 LVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVS 386
Q A+ Q Q P + + P P Q + Q AQ + S
Sbjct: 203 DQVQNLAVRNQQASAQGP-QMQGSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQS 261
Query: 387 QSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSP 446
+ LS G P SM P G P+S + G P + + P P
Sbjct: 262 LN----LSQAGGGSGNSIPGSMGPGGGGQAHGGL-GQLPSSGMGGGSCPRKGTGVVQPLP 316
Query: 447 --------QPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGS---------SQAEE 489
Q SQ+ + + G N +N + +PA S +Q +
Sbjct: 317 AAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQP 376
Query: 490 QQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCE 549
+ + +Q+ +++ + +I + +++ + LL T + + Q+ +
Sbjct: 377 HSLIQQQQQI--HLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATH-LQLAQQQQQQQQQ 433
Query: 550 IALEKLKNDMAVPTPPPPPVPPTKQ 574
++ + P PP VPPT+Q
Sbjct: 434 QQQQQQPQATTLTAPQPPQVPPTQQ 458
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 125 bits (313), Expect = 2e-28
Identities = 119/341 (34%), Positives = 147/341 (43%), Gaps = 27/341 (7%)
Query: 163 QQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIK 222
QQ Q + +L QQQQQQQ Q QQ QQQ Q QQQQQ QQQQQQQQ I
Sbjct: 569 QQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQ---QQQQQQQQQQQQQQSSIS 625
Query: 223 LHHQNQQQ--IQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQP 280
Q QQQ I QQQQ Q+ Q Q QQQQQQQQQQQQQQ + AQ QP ++ P P
Sbjct: 626 AQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLP 685
Query: 281 PPSQALPQQLQQMHHT----QHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPG 336
+ L QQ+Q Q Q Q Q V QN P + P
Sbjct: 686 LQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQ 745
Query: 337 QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSP 396
Q L Q + Q + Q QQ Q A+ +AP Q+++ LS P
Sbjct: 746 QSLLNQQ----LMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRH----LSRP 797
Query: 397 SPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSN------VSSGPAPSPSSFLPSPSPQPSQ 450
P + Q P G + NSN VS+ +P+S L S S ++
Sbjct: 798 PPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTS-HGTR 856
Query: 451 SPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQ 491
P + QN + P N P N SV S G +Q +Q+
Sbjct: 857 MPSLSTAVQNMGMYGNLPCNQP-NTYSVTS--GMNQLTQQR 894
Score = 95.1 bits (235), Expect = 2e-19
Identities = 118/413 (28%), Positives = 148/413 (35%), Gaps = 107/413 (25%)
Query: 88 LTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTA 147
LT GP+ G+ + P GP S+ + P Q P T A S A
Sbjct: 372 LTQGPS-GSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGA-------SRA 423
Query: 148 TPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQ---------------------- 185
P Q +V+ QQ +Q +QQ A +QQ QQQ Q
Sbjct: 424 LPSWQ----EVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEK 479
Query: 186 -------QQQFQAQQSAM--------QQQFQA------------------VVQQQQQLQQ 212
QQ F Q S M Q + A + Q+ Q L +
Sbjct: 480 IPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSR 539
Query: 213 ---------QQQQQQHLIKLHHQNQQQIQQQQQQL----QRIAQLQLQQQQQQQQQQQQQ 259
+ +Q + L H N Q QQ + + + L QQQQQQQQQQQQ
Sbjct: 540 SFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQ 599
Query: 260 QQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLP 319
QQQ Q Q QQ QQ Q S + QQ QQ Q Q QQ Q Q Q
Sbjct: 600 QQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQ 659
Query: 320 PQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV 379
Q Q QP AQ+LP Q L +R+P+ +QQ + Q+Q Q A
Sbjct: 660 QQQQQQPSSQPAQSLPSQPL--------LRSPLPLQQKLLLQQMQNQPIA---------- 701
Query: 380 APGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSP--QPGQPSSQPNSNVS 430
G QVSQ Q Q+ P P P+P P S NS S
Sbjct: 702 GMGYQVSQQQ-------RQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQS 747
Score = 32.3 bits (72), Expect = 1.6
Identities = 43/165 (26%), Positives = 58/165 (35%), Gaps = 21/165 (12%)
Query: 312 QNQPSQLPPQSQTQPLVSQAQALPG--QMLYTQPPLK-------FVRAPMVVQQPPVQPQ 362
Q+Q S P + +V +++ PG Q P L+ F A + P
Sbjct: 347 QSQRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPS 406
Query: 363 VQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPS 422
V Q Q QT A P Q + + + QQ Q QP+ PS
Sbjct: 407 VPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPS 466
Query: 423 SQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPG 467
S+GP+P P PSP Q +PQ S P PG
Sbjct: 467 -------SAGPSPGPFGQEKIPSPSFGQQTF---SPQ--SSPMPG 499
Score = 32.3 bits (72), Expect = 1.6
Identities = 33/142 (23%), Positives = 55/142 (38%), Gaps = 16/142 (11%)
Query: 254 QQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQN 313
Q+ +QQ+AL + ++ P P+Q+L Q + +Q P
Sbjct: 969 QEGTSKQQEALTSAG-VRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAP----------- 1016
Query: 314 QPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTA 373
P+QL P Q +P+ +Q L GQ T PL+ + + P + Q T + +
Sbjct: 1017 -PNQLTPAVQMRPMNQMSQTLNGQ---TMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQS 1072
Query: 374 QAAQMVAPGVQVSQSSLPMLSS 395
+ P + S P SS
Sbjct: 1073 RTGINQPPSLTPSNFPSPNQSS 1094
>gi|169164745 PREDICTED: similar to hCG2014450 [Homo sapiens]
Length = 297
Score = 123 bits (308), Expect = 7e-28
Identities = 61/90 (67%), Positives = 69/90 (76%), Gaps = 10/90 (11%)
Query: 593 VFNHSLYRTFVPAMTAIHGPPIT----------APVVCTRKRRLEDDERQSIPSVLQGEV 642
+FNHSLY F+P + AIH PPIT APVVCTRK RLEDDE+QSI SVLQG V
Sbjct: 62 LFNHSLYCIFMPTLIAIHSPPITYIQLGWASRRAPVVCTRKHRLEDDEQQSISSVLQGLV 121
Query: 643 ARLDPKFLVNLDPSHCSNNGTVHLICKLDD 672
ARL+PK ++NLDPSHCSNNGTV LICKL +
Sbjct: 122 ARLEPKCMINLDPSHCSNNGTVRLICKLGE 151
>gi|169163050 PREDICTED: hypothetical protein LOC100127989 [Homo
sapiens]
Length = 297
Score = 123 bits (308), Expect = 7e-28
Identities = 61/90 (67%), Positives = 69/90 (76%), Gaps = 10/90 (11%)
Query: 593 VFNHSLYRTFVPAMTAIHGPPIT----------APVVCTRKRRLEDDERQSIPSVLQGEV 642
+FNHSLY F+P + AIH PPIT APVVCTRK RLEDDE+QSI SVLQG V
Sbjct: 62 LFNHSLYCIFMPTLIAIHSPPITYIQLGWASRRAPVVCTRKHRLEDDEQQSISSVLQGLV 121
Query: 643 ARLDPKFLVNLDPSHCSNNGTVHLICKLDD 672
ARL+PK ++NLDPSHCSNNGTV LICKL +
Sbjct: 122 ARLEPKCMINLDPSHCSNNGTVRLICKLGE 151
>gi|169164311 PREDICTED: similar to hCG2014450 [Homo sapiens]
Length = 297
Score = 122 bits (305), Expect = 2e-27
Identities = 60/90 (66%), Positives = 69/90 (76%), Gaps = 10/90 (11%)
Query: 593 VFNHSLYRTFVPAMTAIHGPPIT----------APVVCTRKRRLEDDERQSIPSVLQGEV 642
+FNHSLY F+P + AIH PPIT APVVCTRK RLEDDE+QSI S+LQG V
Sbjct: 62 LFNHSLYCIFMPTLIAIHSPPITYIQLGWASRRAPVVCTRKHRLEDDEQQSISSMLQGLV 121
Query: 643 ARLDPKFLVNLDPSHCSNNGTVHLICKLDD 672
ARL+PK ++NLDPSHCSNNGTV LICKL +
Sbjct: 122 ARLEPKCMINLDPSHCSNNGTVRLICKLGE 151
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 113 bits (282), Expect = 7e-25
Identities = 82/164 (50%), Positives = 95/164 (57%), Gaps = 19/164 (11%)
Query: 143 VVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAAL-------QQQQQQQQQQQFQAQQSA 195
V+S Q LQ QQ + QQQQ Q+F ++QQ L QQQQQQQQQQQ Q QQ
Sbjct: 112 VLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQ 171
Query: 196 MQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQ--QQQ 253
QQQ Q QQQQQ QQQQQQQQH K Q ++Q QQQQQQ Q AQ + QQQ Q Q
Sbjct: 172 QQQQQQ---QQQQQQQQQQQQQQHPGK---QAKEQQQQQQQQQQLAAQQLVFQQQLLQMQ 225
Query: 254 QQQQQQQQQALQAQPPIQQPPMQQPQP----PPSQALPQQLQQM 293
Q QQQQ +LQ Q I PP Q P P + P ++QQ+
Sbjct: 226 QLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQL 269
Score = 108 bits (269), Expect = 2e-23
Identities = 85/190 (44%), Positives = 96/190 (50%), Gaps = 21/190 (11%)
Query: 140 SMAVVSTATPQTQLQ-LQQVALQQQQQQQQFQQQQQAALQQQQQQQ--QQQQFQAQQSAM 196
+M TPQ Q LQQ L QQ Q QQQQ LQQQQ Q+ ++QQ Q +
Sbjct: 92 AMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLL 151
Query: 197 QQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQ 256
QQQ Q QQQQQ QQQQQQQQ Q QQQ QQQQQQ Q+ Q +Q ++QQQQQ
Sbjct: 152 QQQQQQQQQQQQQQQQQQQQQQ-------QQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQ 204
Query: 257 QQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPS 316
QQQQQ A Q Q QQ +Q QQLQQ H Q PP P
Sbjct: 205 QQQQQLAAQ-QLVFQQQLLQM----------QQLQQQQHLLSLQRQGLISIPPGQAALPV 253
Query: 317 QLPPQSQTQP 326
Q PQ+ P
Sbjct: 254 QSLPQAGLSP 263
Score = 106 bits (265), Expect = 7e-23
Identities = 100/254 (39%), Positives = 119/254 (46%), Gaps = 40/254 (15%)
Query: 112 GMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQ---QVALQQQ----- 163
GM +L + S G+ +SG ++ V Q Q LQ Q+ LQQQ
Sbjct: 19 GMSTLSSQLDAGSRDGR----SSGDTSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLK 74
Query: 164 -----QQQQQFQQQQQAAL--------QQQQQQQQQQQFQAQQ-SAMQQQFQAVVQQQQQ 209
+Q+ Q A+ QQ QQ QQQ QQ A+ QQ QAV+ QQQQ
Sbjct: 75 SPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQ 134
Query: 210 LQQ---QQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQA 266
LQ+ +QQ+Q HL L Q QQQ QQQQQQ Q Q Q QQQQQQQQQQQQQQQQ Q
Sbjct: 135 LQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQ---QQQQQQQQQQQQQQQQQQQQQQQQ 191
Query: 267 QPPIQQPPMQQPQPPPSQ------ALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQ--L 318
P Q QQ Q Q QQL QM Q Q Q+ + P Q L
Sbjct: 192 HPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAAL 251
Query: 319 PPQSQTQPLVSQAQ 332
P QS Q +S A+
Sbjct: 252 PVQSLPQAGLSPAE 265
Score = 63.2 bits (152), Expect = 9e-10
Identities = 68/256 (26%), Positives = 94/256 (36%), Gaps = 42/256 (16%)
Query: 151 TQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQL 210
T ++ V L QQQQ Q +Q LQQQ + + +Q +Q + Q +
Sbjct: 40 TSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVI 99
Query: 211 QQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPI 270
QQ +QQ QQQ QQ Q LQ Q +
Sbjct: 100 TPQQ-------------------------------MQQILQQQVLSPQQLQALLQQQQAV 128
Query: 271 --QQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLV 328
QQ +Q+ + L QL Q Q Q Q QQ Q Q Q Q Q Q
Sbjct: 129 MLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-- 186
Query: 329 SQAQALPG-----QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGV 383
Q Q PG Q Q + +V QQ +Q Q QQQ + + Q +++ +
Sbjct: 187 QQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLIS--I 244
Query: 384 QVSQSSLPMLSSPSPG 399
Q++LP+ S P G
Sbjct: 245 PPGQAALPVQSLPQAG 260
Score = 50.1 bits (118), Expect = 8e-06
Identities = 71/259 (27%), Positives = 90/259 (34%), Gaps = 43/259 (16%)
Query: 233 QQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQ 292
QQQQ LQ QL LQQQ + + +Q P+Q P + P PQQ+QQ
Sbjct: 53 QQQQALQAARQLLLQQQTSGLKSPKSSDKQR-----PLQVP-VSVAMMTPQVITPQQMQQ 106
Query: 293 MHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPM 352
+ Q PQ Q + Q Q L Q + Q + L Q+L Q
Sbjct: 107 I--LQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQ---------- 154
Query: 353 VVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPP 412
Q Q QQQQ Q Q Q Q Q QQ Q Q P
Sbjct: 155 -------QQQQQQQQQQQQQQQQQQQQQQQQQQQQ------------QQQQQQQQQHPGK 195
Query: 413 QPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTP 472
Q Q Q Q +++ L Q Q ++ + S+P PG P
Sbjct: 196 QAKEQ--QQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIP-PGQAALP 252
Query: 473 VNPSSVMSPAGSSQAEEQQ 491
V + AG S AE QQ
Sbjct: 253 VQS---LPQAGLSPAEIQQ 268
Score = 31.2 bits (69), Expect = 3.7
Identities = 26/107 (24%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Query: 223 LHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282
L H N + + Q Q+Q+ QQ + Q +++++ QA+ + +P +P P P
Sbjct: 364 LKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHM-RPSEPKPSPKP 422
Query: 283 -----SQALPQQLQQMHHTQHHQPPPQPQQP--PVAQNQPSQLPPQS 322
S + + + + Q P P P P+ Q PS + P S
Sbjct: 423 LNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQG-PSVITPAS 468
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 112 bits (279), Expect = 2e-24
Identities = 75/158 (47%), Positives = 91/158 (57%), Gaps = 7/158 (4%)
Query: 143 VVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQA 202
V+S Q LQ QQ + QQQQ Q+F ++QQ L Q QQQQQQ Q QQ QQQ Q
Sbjct: 20 VLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQ 79
Query: 203 VVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQ 262
QQQQQ QQQQQQQQ + + ++ QQQQQQ Q++A QL QQQ Q QQ QQQQ
Sbjct: 80 QQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQ 139
Query: 263 ---ALQAQPPIQQPPMQQPQP----PPSQALPQQLQQM 293
+LQ Q I PP Q P P + P ++QQ+
Sbjct: 140 HLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQL 177
Score = 107 bits (268), Expect = 3e-23
Identities = 85/189 (44%), Positives = 95/189 (50%), Gaps = 21/189 (11%)
Query: 141 MAVVSTATPQTQLQ-LQQVALQQQQQQQQFQQQQQAALQQQQQQQ--QQQQFQAQQSAMQ 197
M TPQ Q LQQ L QQ Q QQQQ LQQQQ Q+ ++QQ Q +Q
Sbjct: 1 MMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQ 60
Query: 198 QQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQ 257
QQ Q QQQQQ QQQQQQQQ Q QQQ QQQQQQ Q+ Q +Q ++QQQQQQ
Sbjct: 61 QQQQQQQQQQQQQQQQQQQQQ-------QQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQ 113
Query: 258 QQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQ 317
QQQQ A Q Q QQ +Q QQLQQ H Q PP P Q
Sbjct: 114 QQQQLAAQ-QLVFQQQLLQM----------QQLQQQQHLLSLQRQGLISIPPGQAALPVQ 162
Query: 318 LPPQSQTQP 326
PQ+ P
Sbjct: 163 SLPQAGLSP 171
Score = 104 bits (260), Expect = 3e-22
Identities = 80/167 (47%), Positives = 89/167 (53%), Gaps = 15/167 (8%)
Query: 178 QQQQQQQQQQQFQAQQ-SAMQQQFQAVVQQQQQLQQ---QQQQQQHLIKLHHQNQQQIQQ 233
QQ QQ QQQ QQ A+ QQ QAV+ QQQQLQ+ +QQ+Q HL L Q QQQ QQ
Sbjct: 10 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 69
Query: 234 QQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQ------ALP 287
QQQQ Q Q Q QQQQQQQQQQQQQQQQ Q P Q QQ Q Q
Sbjct: 70 QQQQQQ---QQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQ 126
Query: 288 QQLQQMHHTQHHQPPPQPQQPPVAQNQPSQ--LPPQSQTQPLVSQAQ 332
QQL QM Q Q Q+ + P Q LP QS Q +S A+
Sbjct: 127 QQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAE 173
Score = 91.3 bits (225), Expect = 3e-18
Identities = 113/393 (28%), Positives = 162/393 (41%), Gaps = 44/393 (11%)
Query: 184 QQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQ 243
QQ QQ QQ QQ QA++QQQQ + QQQQ Q K +QQ+QL +
Sbjct: 10 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYK----------KQQEQLH-LQL 58
Query: 244 LQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPP 303
LQ QQQQQQQQQQQQQQQQ Q Q QQ QQ Q Q +Q ++ Q Q
Sbjct: 59 LQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQL 118
Query: 304 QPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPP----LKFVRAPMVVQQPPV 359
QQ V Q Q Q+ Q Q L+S L Q L + PP L P P
Sbjct: 119 AAQQ-LVFQQQLLQMQQLQQQQHLLS----LQRQGLISIPPGQAALPVQSLPQAGLSPAE 173
Query: 360 QPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPG 419
Q+ ++ T V + + + G+ ++ ++ +S + T ++ PP S G
Sbjct: 174 IQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSN------TSKASPPITHHSIVNG 227
Query: 420 QPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSP-GPLNTPVNPSSV 478
Q S+V S S SS + + + P S+ G +N
Sbjct: 228 Q------SSVLSARRDS-SSHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHA 280
Query: 479 MSPAGSSQAEEQ-QYLDKLK-QLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDP 536
+ ++Q Q Q + +L+ QLSK E L+ M+ + K K +L+ +T
Sbjct: 281 LDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVT-- 338
Query: 537 SKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPV 569
+ E + + L PT P P+
Sbjct: 339 ------MSKNMLETSPQSLPQTPTTPTAPVTPI 365
Score = 57.8 bits (138), Expect = 4e-08
Identities = 53/168 (31%), Positives = 70/168 (41%), Gaps = 11/168 (6%)
Query: 239 QRIAQLQLQQQQQQQQQQQQQQQQALQAQPPI--QQPPMQQPQPPPSQALPQQLQQMHHT 296
Q I Q+QQ QQQ QQ Q LQ Q + QQ +Q+ + L QL Q
Sbjct: 5 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ 64
Query: 297 QHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPG-----QMLYTQPPLKFVRAP 351
Q Q Q QQ Q Q Q Q Q Q Q Q PG Q Q +
Sbjct: 65 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ--QQQQQHPGKQAKEQQQQQQQQQQLAAQQ 122
Query: 352 MVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPG 399
+V QQ +Q Q QQQ + + Q +++ + Q++LP+ S P G
Sbjct: 123 LVFQQQLLQMQQLQQQQHLLSLQRQGLIS--IPPGQAALPVQSLPQAG 168
Score = 35.4 bits (80), Expect = 0.19
Identities = 55/210 (26%), Positives = 69/210 (32%), Gaps = 37/210 (17%)
Query: 282 PSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYT 341
P PQQ+QQ+ Q PQ Q + Q Q L Q + Q + L Q+L
Sbjct: 4 PQVITPQQMQQI--LQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQ 61
Query: 342 QPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQ 401
Q Q Q QQQQ Q Q Q Q Q QQ
Sbjct: 62 Q-----------------QQQQQQQQQQQQQQQQQQQQQQQQQQQQ------------QQ 92
Query: 402 VQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNF 461
Q Q P Q Q Q Q +++ L Q Q ++ +
Sbjct: 93 QQQQQQQHPGKQAKEQ--QQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLI 150
Query: 462 SVPSPGPLNTPVNPSSVMSPAGSSQAEEQQ 491
S+P PG PV + AG S AE QQ
Sbjct: 151 SIP-PGQAALPVQS---LPQAGLSPAEIQQ 176
Score = 31.2 bits (69), Expect = 3.7
Identities = 26/107 (24%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Query: 223 LHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282
L H N + + Q Q+Q+ QQ + Q +++++ QA+ + +P +P P P
Sbjct: 272 LKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHM-RPSEPKPSPKP 330
Query: 283 -----SQALPQQLQQMHHTQHHQPPPQPQQP--PVAQNQPSQLPPQS 322
S + + + + Q P P P P+ Q PS + P S
Sbjct: 331 LNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQG-PSVITPAS 376
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 112 bits (279), Expect = 2e-24
Identities = 78/164 (47%), Positives = 93/164 (56%), Gaps = 25/164 (15%)
Query: 143 VVSTATPQT----QLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQ 198
++ST TP + Q ++ A+ +QQQQQ QQQQQ QQQQQQQQQQQ Q QQ
Sbjct: 2026 MISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQ---QYHIRQQ 2082
Query: 199 QFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQ 258
Q Q +++QQQQ QQQQQQQQ Q QQQ QQQQQ QQ QQQQQQQ
Sbjct: 2083 QQQQILRQQQQQQQQQQQQQ-------QQQQQQQQQQQ----------QQHQQQQQQQAA 2125
Query: 259 QQQQALQAQPPIQQPPMQQ-PQPPPSQALPQQLQQMHHTQHHQP 301
Q Q+QP Q+ +QQ Q + AL +QLQQ QP
Sbjct: 2126 PPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQP 2169
Score = 107 bits (266), Expect = 5e-23
Identities = 93/241 (38%), Positives = 110/241 (45%), Gaps = 38/241 (15%)
Query: 95 GAAGIGMPPR---GPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAP---HSMAVVSTAT 148
G AG +PP P QS + + L +P AP H + +
Sbjct: 1958 GPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFS 2017
Query: 149 PQTQLQLQQVALQQQQQQQQFQQ--QQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQ 206
QT Q ++ Q Q + A L +QQQQQQQQQ Q QQ QQQ QQ
Sbjct: 2018 HQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQ----QQQ 2073
Query: 207 QQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQA 266
QQQ +QQQQQ +++ Q QQQ QQQQQQ QQQQQQQQQQQ QQQQ QA
Sbjct: 2074 QQQYHIRQQQQQQILRQQQQQQQQQQQQQQQ---------QQQQQQQQQQQHQQQQQQQA 2124
Query: 267 QPPIQQPPMQQPQPPPSQALPQ-QLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQ 325
PP QPQP Q+ PQ Q Q + TQ Q QQ Q Q +Q Q
Sbjct: 2125 APP-------QPQP---QSQPQFQRQGLQQTQ------QQQQTAALVRQLQQQLSNTQPQ 2168
Query: 326 P 326
P
Sbjct: 2169 P 2169
Score = 95.1 bits (235), Expect = 2e-19
Identities = 90/240 (37%), Positives = 100/240 (41%), Gaps = 40/240 (16%)
Query: 114 GSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQ--------- 164
G G M P S S QP T H + P LQ + QQ
Sbjct: 1958 GPAGTMVPP-SYSSQPYQST-----HPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLT 2011
Query: 165 QQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLH 224
Q+F Q LQQ AQ + A++ +QQQ QQQQQQQQ
Sbjct: 2012 STQRFSHQ---TLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQ----- 2063
Query: 225 HQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQ 284
QQQ QQQQQQ Q+ Q QQQQ +QQQQQQQQQ Q Q QQ QQ
Sbjct: 2064 ---QQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQ------- 2113
Query: 285 ALPQQLQQMHHTQHHQPPPQPQQPPVAQNQP-SQLPPQSQTQPLVSQAQALPGQMLYTQP 343
QQ QQ Q P PQPQ P Q Q Q Q QT LV Q Q Q+ TQP
Sbjct: 2114 ---QQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQ---QLSNTQP 2167
Score = 51.2 bits (121), Expect = 3e-06
Identities = 62/245 (25%), Positives = 85/245 (34%), Gaps = 22/245 (8%)
Query: 193 QSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQ------IQQQQQQLQRIAQLQL 246
++++ +Q Q V Q Q+L+QQ QQ Q ++ +Q +Q Q ++ + L
Sbjct: 1894 KTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGL 1953
Query: 247 QQQQQQQQQQ--QQQQQQALQAQPPIQQPPMQQP----QPPPSQALPQQLQQMHH----T 296
QQ Q Q+ P P + P Q PS + QQ H T
Sbjct: 1954 QQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTST 2013
Query: 297 QHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQ 356
Q Q P ++ P Q V LP Q Q + + QQ
Sbjct: 2014 QRFSHQTLQQTPMISTMTPMSA---QGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQ 2070
Query: 357 PPVQPQV---QQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQ 413
Q Q QQQQ + Q Q Q Q QQ Q Q+ PP PQ
Sbjct: 2071 QQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQ 2130
Query: 414 PSPQP 418
P QP
Sbjct: 2131 PQSQP 2135
Score = 32.7 bits (73), Expect = 1.3
Identities = 26/64 (40%), Positives = 27/64 (42%), Gaps = 19/64 (29%)
Query: 150 QTQLQLQQVALQQQQQQ-------------------QQFQQQQQAALQQQQQQQQQQQFQ 190
Q Q Q QQ QQQQQQ QQ QQQQQ A +Q QQQ Q
Sbjct: 2107 QQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQ 2166
Query: 191 AQQS 194
Q S
Sbjct: 2167 PQPS 2170
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 111 bits (278), Expect = 2e-24
Identities = 78/160 (48%), Positives = 90/160 (56%), Gaps = 11/160 (6%)
Query: 143 VVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAAL-----QQQQQQQQQQQFQAQQSAMQ 197
V+S Q LQ QQ + QQQQ Q+F ++QQ L QQQQQQQQQQQ Q QQ Q
Sbjct: 137 VLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQ 196
Query: 198 QQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQ 257
QQ Q QQQQQ QQQQQQQQ + QQQ QQQQQQL + QQ Q QQ QQ
Sbjct: 197 QQQQQ--QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQ 254
Query: 258 QQQQQALQAQPPIQQPPMQQPQP----PPSQALPQQLQQM 293
QQ +LQ Q I PP Q P P + P ++QQ+
Sbjct: 255 QQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQL 294
Score = 111 bits (277), Expect = 3e-24
Identities = 90/206 (43%), Positives = 105/206 (50%), Gaps = 23/206 (11%)
Query: 126 SGQPPPGTSGMAPHSMAVVS--TATPQTQLQ-LQQVALQQQQQQQQFQQQQQAALQQQQQ 182
SG P + P S+A+++ TPQ Q LQQ L QQ Q QQQQ LQQQQ
Sbjct: 101 SGDGHPHNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQL 160
Query: 183 QQ--QQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQR 240
Q+ ++QQ Q +QQQ Q QQQQQ QQQQQQQQ Q QQQ QQQQQQ Q+
Sbjct: 161 QEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQ-------QQQQQQQQQQQQQQQ 213
Query: 241 IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ 300
Q +Q ++QQQQQQQQQQ A Q Q QQ +Q QQLQQ H Q
Sbjct: 214 QQQHPGKQAKEQQQQQQQQQQLAAQ-QLVFQQQLLQM----------QQLQQQQHLLSLQ 262
Query: 301 PPPQPQQPPVAQNQPSQLPPQSQTQP 326
PP P Q PQ+ P
Sbjct: 263 RQGLISIPPGQAALPVQSLPQAGLSP 288
Score = 104 bits (260), Expect = 3e-22
Identities = 80/167 (47%), Positives = 89/167 (53%), Gaps = 15/167 (8%)
Query: 178 QQQQQQQQQQQFQAQQ-SAMQQQFQAVVQQQQQLQQ---QQQQQQHLIKLHHQNQQQIQQ 233
QQ QQ QQQ QQ A+ QQ QAV+ QQQQLQ+ +QQ+Q HL L Q QQQ QQ
Sbjct: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
Query: 234 QQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQ------ALP 287
QQQQ Q Q Q QQQQQQQQQQQQQQQQ Q P Q QQ Q Q
Sbjct: 187 QQQQQQ---QQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQ 243
Query: 288 QQLQQMHHTQHHQPPPQPQQPPVAQNQPSQ--LPPQSQTQPLVSQAQ 332
QQL QM Q Q Q+ + P Q LP QS Q +S A+
Sbjct: 244 QQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAE 290
Score = 91.3 bits (225), Expect = 3e-18
Identities = 113/393 (28%), Positives = 162/393 (41%), Gaps = 44/393 (11%)
Query: 184 QQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQ 243
QQ QQ QQ QQ QA++QQQQ + QQQQ Q K +QQ+QL +
Sbjct: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYK----------KQQEQLH-LQL 175
Query: 244 LQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPP 303
LQ QQQQQQQQQQQQQQQQ Q Q QQ QQ Q Q +Q ++ Q Q
Sbjct: 176 LQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQL 235
Query: 304 QPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPP----LKFVRAPMVVQQPPV 359
QQ V Q Q Q+ Q Q L+S L Q L + PP L P P
Sbjct: 236 AAQQ-LVFQQQLLQMQQLQQQQHLLS----LQRQGLISIPPGQAALPVQSLPQAGLSPAE 290
Query: 360 QPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPG 419
Q+ ++ T V + + + G+ ++ ++ +S + T ++ PP S G
Sbjct: 291 IQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSN------TSKASPPITHHSIVNG 344
Query: 420 QPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSP-GPLNTPVNPSSV 478
Q S+V S S SS + + + P S+ G +N
Sbjct: 345 Q------SSVLSARRDS-SSHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHA 397
Query: 479 MSPAGSSQAEEQ-QYLDKLK-QLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDP 536
+ ++Q Q Q + +L+ QLSK E L+ M+ + K K +L+ +T
Sbjct: 398 LDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVT-- 455
Query: 537 SKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPV 569
+ E + + L PT P P+
Sbjct: 456 ------MSKNMLETSPQSLPQTPTTPTAPVTPI 482
Score = 65.5 bits (158), Expect = 2e-10
Identities = 70/256 (27%), Positives = 101/256 (39%), Gaps = 17/256 (6%)
Query: 151 TQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQL 210
T ++ V L QQQQ Q +Q LQQQ + + +Q +Q+ + + + +
Sbjct: 40 TSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQE---LLPETKLCI 96
Query: 211 QQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPI 270
H H+ + Q I Q+QQ QQQ QQ Q LQ Q +
Sbjct: 97 CGHSSGDGHP---HNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAV 153
Query: 271 --QQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLV 328
QQ +Q+ + L QL Q Q Q Q QQ Q Q Q Q Q Q
Sbjct: 154 MLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-- 211
Query: 329 SQAQALPG-----QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGV 383
Q Q PG Q Q + +V QQ +Q Q QQQ + + Q +++ +
Sbjct: 212 QQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLIS--I 269
Query: 384 QVSQSSLPMLSSPSPG 399
Q++LP+ S P G
Sbjct: 270 PPGQAALPVQSLPQAG 285
Score = 31.2 bits (69), Expect = 3.7
Identities = 26/107 (24%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Query: 223 LHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282
L H N + + Q Q+Q+ QQ + Q +++++ QA+ + +P +P P P
Sbjct: 389 LKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHM-RPSEPKPSPKP 447
Query: 283 -----SQALPQQLQQMHHTQHHQPPPQPQQP--PVAQNQPSQLPPQS 322
S + + + + Q P P P P+ Q PS + P S
Sbjct: 448 LNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQG-PSVITPAS 493
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 109 bits (273), Expect = 8e-24
Identities = 90/208 (43%), Positives = 98/208 (47%), Gaps = 25/208 (12%)
Query: 148 TPQTQLQLQQVALQQQQQQQ---QFQQQQQAALQQQQQQQQQQQFQAQQ------SAMQQ 198
TP+T + QQ QQQQQQ Q QQ LQQQQQQQ QQ QQ QQ
Sbjct: 395 TPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQ 454
Query: 199 QFQAVVQQ--QQQLQQQQQQQQHLIKLHHQNQQ--QIQQQ---QQQLQRIAQLQLQQQQQ 251
Q QA Q QQQLQ QQQ +LH QQ QQQ QQQ ++ Q QLQQQQ
Sbjct: 455 QQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQL 514
Query: 252 QQQQQQ-----QQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ 306
Q QQQ QQQQQ +Q Q + QQ Q SQ P Q QH PP QP
Sbjct: 515 AQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPP 574
Query: 307 QPPVAQNQPSQLPPQSQTQPLVSQAQAL 334
Q Q Q Q PP Q L A+
Sbjct: 575 Q----QQQQQQPPPSPQQHQLFGHDPAV 598
Score = 91.3 bits (225), Expect = 3e-18
Identities = 84/238 (35%), Positives = 104/238 (43%), Gaps = 16/238 (6%)
Query: 139 HSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQS--AM 196
H + +S T + Q+ Q + + QQQQQ Q QQ +
Sbjct: 358 HILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVL 417
Query: 197 QQQFQAVVQQQQQLQQQQQQQQHLIKLHHQ-NQQQIQQQQQQLQRIAQLQLQQQQQ---- 251
Q Q ++Q QQQ QQQ QQ + + H +QQQ QQQQ + +Q QLQ QQ
Sbjct: 418 HLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHP 477
Query: 252 -QQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHH--TQHHQPPPQPQQP 308
QQ + QQQ Q Q Q +QQ Q Q Q QLQQ H Q Q Q QQ
Sbjct: 478 PQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQL 537
Query: 309 PVAQNQPSQLPPQSQTQPLVSQ-AQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQ 365
Q Q QSQT P +SQ +QAL Q+ QPP + QQPP PQ Q
Sbjct: 538 QRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQ-----QQQQQPPPSPQQHQ 590
Score = 89.4 bits (220), Expect = 1e-17
Identities = 85/245 (34%), Positives = 104/245 (42%), Gaps = 14/245 (5%)
Query: 155 LQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQ 214
LQ ++ + +QQ QQ Q + + +QQQ QA QQQQQ
Sbjct: 360 LQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQ-QQQQQHPVLH 418
Query: 215 QQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL-----QAQPP 269
Q Q +++L Q QQQI QQ Q QQQQQQQ Q QQ L Q PP
Sbjct: 419 LQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPP 478
Query: 270 IQ-QPPMQQPQPPPSQ-ALPQQLQQM--HHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQ 325
Q P QQ QP Q AL QQ Q+ H Q Q QQ + Q Q Q Q Q Q
Sbjct: 479 QQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQ 538
Query: 326 PLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQ-PQVQQQQTAVQTAQAAQMVA--PG 382
+ Q Q Q T P L + Q PP Q PQ QQQQ + Q Q+ P
Sbjct: 539 RMHQQQQQQQMQS-QTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQLFGHDPA 597
Query: 383 VQVSQ 387
V++ +
Sbjct: 598 VEIPE 602
Score = 65.5 bits (158), Expect = 2e-10
Identities = 74/299 (24%), Positives = 103/299 (34%), Gaps = 54/299 (18%)
Query: 175 AALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQ 234
AA Q Q ++ + A++ Q + H+++ + ++QQ
Sbjct: 314 AAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQ 373
Query: 235 QQQLQR---------IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQA 285
Q+ +Q+++ + QQQQQ QQQ Q Q P
Sbjct: 374 VNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQ--------------QQQHPVLHL 419
Query: 286 LPQQLQQMHHTQHHQ--PPPQPQQPPVAQNQPSQLPPQ------SQTQPLVSQAQALPGQ 337
PQQ+ Q+ Q Q P PQQPP +Q Q Q SQ Q Q Q P Q
Sbjct: 420 QPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQ 479
Query: 338 MLY----------------------TQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQA 375
L+ Q L+ + + QQ + Q QQQQ Q Q
Sbjct: 480 QLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQR 539
Query: 376 AQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPA 434
Q+ + P LS S Q Q P PP Q QP PS Q + PA
Sbjct: 540 MHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQP-PPSPQQHQLFGHDPA 597
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 107 bits (266), Expect = 5e-23
Identities = 130/470 (27%), Positives = 175/470 (37%), Gaps = 74/470 (15%)
Query: 89 TGGPAAGAAGIG---MPPRGPGQSLGGMGSLGAMGQPMSLSGQPP--PGTSGMAPHSMAV 143
+GGP G AG G M + G + + A G S P PG+SG +A
Sbjct: 317 SGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLA- 375
Query: 144 VSTATPQTQLQLQQVALQQQQQQ---QQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQF 200
TPQ + Q+ + Q + QQQ QQ Q Q+ Q++
Sbjct: 376 ---RTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTP--QRY 430
Query: 201 QAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQ 260
+Q + Q I + Q QQ Q Q QQQQ QQ
Sbjct: 431 PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPP 490
Query: 261 QQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ-PPPQPQQPPVAQNQPSQLP 319
Q AQP QQ P QP P + P QQ H Q P P P Q Q P P
Sbjct: 491 SQTPHAQPSYQQQPQSQP-PQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQP 549
Query: 320 PQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV 379
P SQ QAQ+ P Q Q P AP + Q PQ Q QQ+ QTA + Q
Sbjct: 550 PYSQ-----PQAQS-PYQQQQPQQP-----APSTLSQQAAYPQPQSQQSQ-QTAYSQQRF 597
Query: 380 APGVQVSQ-------SSLPMLSSPSPGQQ------VQTPQSMPP----------PPQPSP 416
P ++SQ SS P ++S GQ+ P S+P + +
Sbjct: 598 PPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGAL 657
Query: 417 QPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQ------PSQSPVTARTPQNFSVPSPGPLN 470
PG +S +S+ P+ S F P SP PS SPV +P + + GPL+
Sbjct: 658 SPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPV--GSPASVAQSRSGPLS 715
Query: 471 TPVNPSSVMSPA---------------GSSQAEEQQYLDKLKQLSKYIEP 505
P + M P SS A+++ Y+ + Q+ +Y P
Sbjct: 716 PAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSP 765
Score = 66.6 bits (161), Expect = 8e-11
Identities = 117/502 (23%), Positives = 164/502 (32%), Gaps = 100/502 (19%)
Query: 112 GMGSLGAMGQPMSLSGQPPPGTSGMAPHSM-------------------AVVSTATPQTQ 152
G G G MG P S + P G M P +ST PQ
Sbjct: 1249 GQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPN 1308
Query: 153 LQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQ-----QQFQAQQSAMQQQFQAVVQQQ 207
L + QQQQQQQQ+ QF Q + F + Q
Sbjct: 1309 LM-------PSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPS----Q 1357
Query: 208 QQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQ 267
Q QQQQQ + + ++ + ++ + Q Q QQQQ Q Q
Sbjct: 1358 QTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSV------PYSTGQGQPQQQQLPPAQPQ 1411
Query: 268 PPIQQPPMQQPQPPPSQALPQQLQQMH-----HTQHHQPP--PQPQQP----------PV 310
P QQ Q QP P Q + Q + +P PQ Q P P
Sbjct: 1412 PASQQ---QAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPP 1468
Query: 311 AQNQPSQLPPQSQTQPLVSQAQ-ALPGQMLYTQPPLKFVRAPM----VVQQPPVQPQVQQ 365
N +PPQ P+ + A+ A G M + + + A Q P V +
Sbjct: 1469 GTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNR 1528
Query: 366 QQTAVQTAQAAQMVAPGVQVSQSSLPM-LSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQ 424
+ T Q A P S+P P P + PPP P P +
Sbjct: 1529 TDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVP------PMTRPPPSNYQPPPSMQNHI 1582
Query: 425 PNSNVSSGPAPSPSSFLPSPSPQP----SQSPVTARTPQNFSVPSPGPLNTPVNPSSVMS 480
P + S P P P SPS P A P S +P P+ P+ +
Sbjct: 1583 PQVS-SPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITF 1641
Query: 481 PAGSSQAEEQQYLDKLKQLSKYI---EPLRRMIN-------------------KIDKNED 518
P GS +A + + + K I E R M++ D N
Sbjct: 1642 PPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSI 1701
Query: 519 RKKDLSKMKSLLDILTDPSKRC 540
+LS++ LL++L + +RC
Sbjct: 1702 MTFNLSQLPGLLELLVEYFRRC 1723
Score = 62.4 bits (150), Expect = 1e-09
Identities = 105/423 (24%), Positives = 139/423 (32%), Gaps = 99/423 (23%)
Query: 81 PMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHS 140
P ++ G + G+ + P G G GQ + Q P P+S
Sbjct: 427 PQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYS 486
Query: 141 MAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQ---FQAQQSAMQ 197
S TP Q QQ Q Q Q Q Q Q QQ Q QQ + +QQS Q
Sbjct: 487 QQPPSQ-TPHAQPSYQQ---QPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQ 542
Query: 198 QQFQAVVQQQQ-QLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQ 256
Q Q+ Q Q Q QQQQ Q+ A L QQ Q Q
Sbjct: 543 QHPQSQPPYSQPQAQSPYQQQQP-------------------QQPAPSTLSQQAAYPQPQ 583
Query: 257 QQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPS 316
QQ QQ + QQ PP PQ+L Q A + PS
Sbjct: 584 SQQSQQTAYS---------QQRFPP-----PQELSQDSFGSQ------------ASSAPS 617
Query: 317 QLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAA 376
+ + + Q+ P + P + + + A
Sbjct: 618 MTSSKGGQEDMNLSLQSRPSSL------------------PDLSGSIDDLPMGTEGA--- 656
Query: 377 QMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPP---QPSPQP-GQPSSQPNSNVSS- 431
++PGV S S +P Q +P + P P PSP P G P+S S
Sbjct: 657 --LSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPL 714
Query: 432 GPAPSPSSFLP--SPS--------PQPSQSPVT------ARTPQ--NFSVPSPGPLNTPV 473
PA P + +P PS P +QS + R PQ +S P PG +P
Sbjct: 715 SPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPR 774
Query: 474 NPS 476
PS
Sbjct: 775 QPS 777
Score = 30.4 bits (67), Expect = 6.3
Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 8/87 (9%)
Query: 406 QSMPPPPQP-----SPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTAR---T 457
+S PPP P SP+ G P S + S P PS S+ S S +Q A
Sbjct: 219 RSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGG 278
Query: 458 PQNFSVPSPGPLNTPVNPSSVMSPAGS 484
P +P P TP + SP+ +
Sbjct: 279 PSAAGGGTPQPTATPTLNQLLTSPSSA 305
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 107 bits (266), Expect = 5e-23
Identities = 130/470 (27%), Positives = 175/470 (37%), Gaps = 74/470 (15%)
Query: 89 TGGPAAGAAGIG---MPPRGPGQSLGGMGSLGAMGQPMSLSGQPP--PGTSGMAPHSMAV 143
+GGP G AG G M + G + + A G S P PG+SG +A
Sbjct: 317 SGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLA- 375
Query: 144 VSTATPQTQLQLQQVALQQQQQQ---QQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQF 200
TPQ + Q+ + Q + QQQ QQ Q Q+ Q++
Sbjct: 376 ---RTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTP--QRY 430
Query: 201 QAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQ 260
+Q + Q I + Q QQ Q Q QQQQ QQ
Sbjct: 431 PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPP 490
Query: 261 QQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ-PPPQPQQPPVAQNQPSQLP 319
Q AQP QQ P QP P + P QQ H Q P P P Q Q P P
Sbjct: 491 SQTPHAQPSYQQQPQSQP-PQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQP 549
Query: 320 PQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV 379
P SQ QAQ+ P Q Q P AP + Q PQ Q QQ+ QTA + Q
Sbjct: 550 PYSQ-----PQAQS-PYQQQQPQQP-----APSTLSQQAAYPQPQSQQSQ-QTAYSQQRF 597
Query: 380 APGVQVSQ-------SSLPMLSSPSPGQQ------VQTPQSMPP----------PPQPSP 416
P ++SQ SS P ++S GQ+ P S+P + +
Sbjct: 598 PPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGAL 657
Query: 417 QPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQ------PSQSPVTARTPQNFSVPSPGPLN 470
PG +S +S+ P+ S F P SP PS SPV +P + + GPL+
Sbjct: 658 SPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPV--GSPASVAQSRSGPLS 715
Query: 471 TPVNPSSVMSPA---------------GSSQAEEQQYLDKLKQLSKYIEP 505
P + M P SS A+++ Y+ + Q+ +Y P
Sbjct: 716 PAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSP 765
Score = 62.4 bits (150), Expect = 1e-09
Identities = 105/423 (24%), Positives = 139/423 (32%), Gaps = 99/423 (23%)
Query: 81 PMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHS 140
P ++ G + G+ + P G G GQ + Q P P+S
Sbjct: 427 PQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYS 486
Query: 141 MAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQ---FQAQQSAMQ 197
S TP Q QQ Q Q Q Q Q Q QQ Q QQ + +QQS Q
Sbjct: 487 QQPPSQ-TPHAQPSYQQ---QPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQ 542
Query: 198 QQFQAVVQQQQ-QLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQ 256
Q Q+ Q Q Q QQQQ Q+ A L QQ Q Q
Sbjct: 543 QHPQSQPPYSQPQAQSPYQQQQP-------------------QQPAPSTLSQQAAYPQPQ 583
Query: 257 QQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPS 316
QQ QQ + QQ PP PQ+L Q A + PS
Sbjct: 584 SQQSQQTAYS---------QQRFPP-----PQELSQDSFGSQ------------ASSAPS 617
Query: 317 QLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAA 376
+ + + Q+ P + P + + + A
Sbjct: 618 MTSSKGGQEDMNLSLQSRPSSL------------------PDLSGSIDDLPMGTEGA--- 656
Query: 377 QMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPP---QPSPQP-GQPSSQPNSNVSS- 431
++PGV S S +P Q +P + P P PSP P G P+S S
Sbjct: 657 --LSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPL 714
Query: 432 GPAPSPSSFLP--SPS--------PQPSQSPVT------ARTPQ--NFSVPSPGPLNTPV 473
PA P + +P PS P +QS + R PQ +S P PG +P
Sbjct: 715 SPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPR 774
Query: 474 NPS 476
PS
Sbjct: 775 QPS 777
Score = 36.2 bits (82), Expect = 0.11
Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 18/124 (14%)
Query: 252 QQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVA 311
QQQQQQQQ+ + Q Q P P P + QQ QQ+ P P P+
Sbjct: 1327 QQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQV-----SSPAPLPR----- 1376
Query: 312 QNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVR-APMVVQQPPVQPQVQQQQTAV 370
P +++T P S +M PP+ AP VQ P ++ + +V
Sbjct: 1377 -------PMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSV 1429
Query: 371 QTAQ 374
+ Q
Sbjct: 1430 EATQ 1433
Score = 35.8 bits (81), Expect = 0.15
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 21/121 (17%)
Query: 230 QIQQQQQQLQRIAQLQLQQQQ-------QQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282
Q QQQQQQ Q Q QQ QQQQ + + P+ +P + P
Sbjct: 1327 QQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSK 1386
Query: 283 SQALPQQLQQMHHTQHHQPP-------PQPQQPPVAQNQPSQLPPQS--QTQPLVSQAQA 333
S L ++ Q PP P P QPP+ + + PP S TQP++ Q +
Sbjct: 1387 SPFLHSGMKM----QKAGPPVPASHIAPAPVQPPMIRRDIT-FPPGSVEATQPVLKQRRR 1441
Query: 334 L 334
L
Sbjct: 1442 L 1442
Score = 34.7 bits (78), Expect = 0.33
Identities = 56/243 (23%), Positives = 78/243 (32%), Gaps = 44/243 (18%)
Query: 300 QPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPV 359
QP P P PS+ PPQ Q Q Q G TQ P
Sbjct: 1306 QPNLMPSNPDSGMYSPSRYPPQQQQQQ--QQRHDSYGNQFSTQ------------GTPSG 1351
Query: 360 QPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQP--SPQ 417
P QQ T Q Q AP + ++ SP ++ ++ PP P +P
Sbjct: 1352 SPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPA 1411
Query: 418 PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSS 477
P QP P P S + +Q + R + TP
Sbjct: 1412 PVQP-----------PMIRRDITFPPGSVEATQPVLKQRRRLTMK-----DIGTPEAWRV 1455
Query: 478 VMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPS 537
+MS AE LD + I D N +LS++ LL++L +
Sbjct: 1456 MMSLKSGLLAESTWALDTIN------------ILLYDDNSIMTFNLSQLPGLLELLVEYF 1503
Query: 538 KRC 540
+RC
Sbjct: 1504 RRC 1506
Score = 32.0 bits (71), Expect = 2.2
Identities = 36/143 (25%), Positives = 52/143 (36%), Gaps = 10/143 (6%)
Query: 67 RDIHNKKSQASVSDP-MNALQSLTGGPA-----AGAAGIGMPPRGPGQSLGGMGSLGAMG 120
+D + +A SDP M++ Q GG A G+G GP Q G +
Sbjct: 1230 KDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVR 1289
Query: 121 QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQ 180
+ + T P+ M + P + + QQQQQQQ +
Sbjct: 1290 TEPGIGPEGNMSTGAPQPNLMP----SNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFST 1345
Query: 181 QQQQQQQQFQAQQSAMQQQFQAV 203
Q F +QQ+ M QQ Q V
Sbjct: 1346 QGTPSGSPFPSQQTTMYQQQQQV 1368
Score = 31.2 bits (69), Expect = 3.7
Identities = 33/122 (27%), Positives = 39/122 (31%), Gaps = 25/122 (20%)
Query: 112 GMGSLGAMGQPMSLSGQPPPGTSGMAPHSM-------------------AVVSTATPQTQ 152
G G G MG P S + P G M P +ST PQ
Sbjct: 1249 GQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPN 1308
Query: 153 LQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQ----SAMQQQFQAVVQQQQ 208
L + QQQQ QQQ+ QF Q S Q + QQQQ
Sbjct: 1309 LMPSNPDSGMYSPSRYPPQQQQQ--QQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQ 1366
Query: 209 QL 210
Q+
Sbjct: 1367 QV 1368
Score = 30.4 bits (67), Expect = 6.3
Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 8/87 (9%)
Query: 406 QSMPPPPQP-----SPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTAR---T 457
+S PPP P SP+ G P S + S P PS S+ S S +Q A
Sbjct: 219 RSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGG 278
Query: 458 PQNFSVPSPGPLNTPVNPSSVMSPAGS 484
P +P P TP + SP+ +
Sbjct: 279 PSAAGGGTPQPTATPTLNQLLTSPSSA 305
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 100 bits (250), Expect = 4e-21
Identities = 97/283 (34%), Positives = 114/283 (40%), Gaps = 32/283 (11%)
Query: 210 LQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPP 269
+QQQ L HH Q +Q QLQ QQQQQQQQQQQQQQQQ Q Q
Sbjct: 226 IQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQ 285
Query: 270 IQ-QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVA-QNQPSQLPPQSQTQPL 327
+Q +PP Q Q P PQ TQ PP Q P A Q P+Q + T
Sbjct: 286 LQARPPQQHQQQQPQGIRPQFTAP---TQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQ 342
Query: 328 VSQAQALPG---QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQ 384
+ LPG Q L +P L V+ P PP P QQ + T QM PG
Sbjct: 343 GWKKAPLPGPMQQQLQARPSLATVQTPS--HPPPPYPFGSQQASQAHT-NFPQMSNPG-- 397
Query: 385 VSQSSLPMLSS--------PSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSS---GP 433
Q + P + S P+P QQ P S Q G P+S P N + GP
Sbjct: 398 --QFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGP 455
Query: 434 APSPSSFLPSPSPQPSQSP------VTARTPQNFSVPSPGPLN 470
P ++ LP QP SP P NF V P N
Sbjct: 456 RPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPN 498
Score = 92.0 bits (227), Expect = 2e-18
Identities = 130/457 (28%), Positives = 169/457 (36%), Gaps = 84/457 (18%)
Query: 71 NKKSQASVSDPMNALQSL---TGGPAAGAAGI---------GMPPRGPGQSLGGMGSLGA 118
N+ ++ PM A S+ G P A GI +PP G S S+ A
Sbjct: 142 NRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSS-----SMMA 196
Query: 119 MG----------QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQ 168
G +P S S P SG+ + S + +Q V++ +Q
Sbjct: 197 PGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPAN 256
Query: 169 FQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQ 228
F Q QQ QQQQQQQQQQQ Q QQ QQQ QA QQ QQQQ Q + Q
Sbjct: 257 FPQLQQQQQQQQQQQQQQQQQQQQQ--QQQQLQARPPQQ---HQQQQPQGIRPQFTAPTQ 311
Query: 229 QQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQ 288
+ QL A LQ Q Q + + P+ P QQ Q PS A Q
Sbjct: 312 VPVPPGWNQLPSGA---LQPPPAQGSLGTMTANQGWK-KAPLPGPMQQQLQARPSLATVQ 367
Query: 289 QLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFV 348
T H PPP P A + P S PGQ +T P +K +
Sbjct: 368 -------TPSHPPPPYPFGSQQASQAHTNFPQMSN-----------PGQ--FTAPQMKSL 407
Query: 349 R-APMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQS 407
+ P V P QP + + A + + Q +P SSP+ Q Q Q
Sbjct: 408 QGGPSRVPTPLQQPHLTNKSPA-SSPSSFQQGSPA-----------SSPTVNQTQQ--QM 453
Query: 408 MPPPPQPSPQP---GQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSP---------VTA 455
P PPQ +P P QP S P N P +F+ P+Q P +
Sbjct: 454 GPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPK 513
Query: 456 RTPQNFSVPSPGP-LNTPVNPSSVMSPAGSSQAEEQQ 491
R P FS P PS+ + G+S A + Q
Sbjct: 514 RLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQ 550
Score = 65.5 bits (158), Expect = 2e-10
Identities = 86/341 (25%), Positives = 123/341 (36%), Gaps = 37/341 (10%)
Query: 162 QQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLI 221
Q +Q+ QQ +Q Q Q Q Q QQQ Q Q QQQQQQQQ ++
Sbjct: 976 QPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMM 1035
Query: 222 KL-HHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL-QAQPPIQQPPMQQPQ 279
L Q+ + ++ Q + L Q+ QQ + Q P PP Q
Sbjct: 1036 MLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQ 1095
Query: 280 PPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPG--- 336
P + + P P P+A + + LP S S+A ++PG
Sbjct: 1096 RMPMPVNTPLGSNSRKMVYQESPQNPSSSPLA--EMASLPEASG-----SEAPSVPGGPN 1148
Query: 337 -----------QMLYTQPPLKFVRAPMVVQQ--PPVQPQVQQQQTAVQTAQAAQMVAPGV 383
Q++ T P K +P+ Q P QP V ++ VA
Sbjct: 1149 NMPSHVVLPQNQLMMTGP--KPGPSPLSATQGATPQQPPVNSLPSS--HGHHFPNVAAPT 1204
Query: 384 QVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPS 443
Q S+ P +SP P QTP + PP +PS P N S P +P
Sbjct: 1205 QTSRPKTPNRASPRP-YYPQTPNNRPPSTEPSEISLSPE---RLNASIAGLFPPQINIPL 1260
Query: 444 PSPQPSQS---PVTARTPQNFSVPSPGPLNTPVNPSSVMSP 481
P P+P+ + P P N +NPS+ +P
Sbjct: 1261 P-PRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATP 1300
Score = 65.1 bits (157), Expect = 2e-10
Identities = 83/342 (24%), Positives = 117/342 (34%), Gaps = 38/342 (11%)
Query: 102 PPRGPGQSLGGMGSLGAMGQPMSLSGQPPPG-TSGMAPHSMAVVSTATPQTQLQLQQVAL 160
P +GP G+G + P +GQ P G P + A + QLQ Q +
Sbjct: 497 PNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQ-NV 555
Query: 161 QQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQ---FQAVVQQQQQLQQQQQQQ 217
Q Q Q Q + Q M Q V Q Q Q QQ
Sbjct: 556 QHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQ 615
Query: 218 QHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQ 277
+L +QQ + Q Q +Q+ L Q + Q Q Q + P P Q
Sbjct: 616 GPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQ 675
Query: 278 PQPPPSQALPQQLQQMHHTQHHQPPPQ-----PQQPPVAQNQPSQLPPQSQTQPLVSQAQ 332
PP Q L QQ QM + PQ Q P + Q +Q+ Q +Q+
Sbjct: 676 RMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSN 735
Query: 333 ALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPM 392
+PG P + +R P P +Q + QM+ V+ S
Sbjct: 736 VMPG-------PAQIMRGPT--------PNMQGNMVQFTGQMSGQMLPQQGPVNNS---- 776
Query: 393 LSSPSPGQQVQTPQSMPPPPQPSP----QPGQPSSQPNSNVS 430
P Q + + PP PSP Q G P++ N++VS
Sbjct: 777 -----PSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVS 813
Score = 47.8 bits (112), Expect = 4e-05
Identities = 104/479 (21%), Positives = 149/479 (31%), Gaps = 88/479 (18%)
Query: 108 QSLGGMGSLGAMGQPMSLSGQPP----PGTSGMAPH--SMAVVSTATPQTQLQLQQVALQ 161
Q GG G+ G M +S PP P G+ + + ++ PQ L Q Q
Sbjct: 556 QHAGGQGA-GPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQ 614
Query: 162 QQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQ---------- 211
Q Q QQ Q Q QQQ Q + + Q + Q Q +
Sbjct: 615 QGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSP 674
Query: 212 ------QQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQ---QQQ- 261
+Q QQ + NQ Q Q LQ+ ++ Q Q +QQ Q Q
Sbjct: 675 QRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQS 734
Query: 262 -------QALQAQPPIQQPPMQQ----------PQPPPSQALPQQLQQMHHTQHHQPPPQ 304
Q ++ P Q M Q PQ P P Q+ + P P
Sbjct: 735 NVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPS 794
Query: 305 PQ------QPPVAQNQP---SQLPPQ---SQTQPLVSQAQALPG---------------- 336
P P N SQ+ P QT + QA+ G
Sbjct: 795 PHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFN 854
Query: 337 ----------QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVS 386
QM Q P V + + P + +Q +A +
Sbjct: 855 APFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKP 914
Query: 387 QSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPS--P 444
+ P + Q + TP + P + + QP P Q + +SGP S P P
Sbjct: 915 KKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYP 974
Query: 445 SPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVM----SPAGSSQAEEQQYLDKLKQL 499
S Q P+ PQ +P P P + P SQ + QQ + +Q+
Sbjct: 975 SQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQM 1033
Score = 41.2 bits (95), Expect = 0.004
Identities = 82/403 (20%), Positives = 140/403 (34%), Gaps = 72/403 (17%)
Query: 122 PMSLSGQPPPGT----SGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAAL 177
P L+ P PG+ SG+ P + V A V + ++ Q +
Sbjct: 1378 PTPLANPPVPGSFPNNSGLNPQNSTVSVAA----------VGGVVEDNKESLNVPQDSDC 1427
Query: 178 QQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQ 237
Q Q +++Q + + + Q+ + VV + Q + Q + + +N+ + ++
Sbjct: 1428 QNSQSRKEQVNIELK-AVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMRE 1486
Query: 238 LQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQ----------PPMQQ----PQPPPS 283
L + L+ PP+ P +Q +P S
Sbjct: 1487 APTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNS 1546
Query: 284 QALPQ-----------QLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQT-----QPL 327
LP +L ++ PP +P + + + LPP T P+
Sbjct: 1547 LNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPI 1606
Query: 328 VSQAQALPGQMLYTQPPLKFVRAPMVVQQPPV--QPQVQQQQTAVQTAQAAQMVAPGVQV 385
+ A + Q L VV P + V + Q+A Q+ Q + P
Sbjct: 1607 TTSANTSAALPTHLQSALMST----VVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFIN 1662
Query: 386 SQSSLPML--SSPS--PGQQVQTPQSMPPP------PQPSPQPGQPSSQPNSNVSSGPAP 435
S S + ++ S PS P + T + PP P PQ N SS P P
Sbjct: 1663 SSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQ--------NIKFSSAPVP 1714
Query: 436 SPSSFLPSPSP--QPSQSPVTARTPQNFSVPSPGPLNTPVNPS 476
P++ SP+P Q + V + +PSP ++PV PS
Sbjct: 1715 -PNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPS 1756
Score = 34.3 bits (77), Expect = 0.43
Identities = 61/300 (20%), Positives = 100/300 (33%), Gaps = 57/300 (19%)
Query: 391 PMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGP-APSPSSFLPSPSPQPS 449
PM + S + P + P P P NVSS AP P+ L +P+P+
Sbjct: 152 PMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPA 211
Query: 450 QSPVTARTP---------QNFSVPSPGPLNTPVNPSSV---MSPAGSSQAEEQQYLDKLK 497
S A P Q+ S P + P+ P SV M+PA Q ++QQ + +
Sbjct: 212 -SQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQ 270
Query: 498 QLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPS-------------------- 537
Q + + ++ ++ ++ + + + T P+
Sbjct: 271 QQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPP 330
Query: 538 --------------KRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQQYLCQPLLD 583
K+ PL + ++ + P+ PPPP P QQ
Sbjct: 331 AQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQ-------- 382
Query: 584 AVLANIRSPVFNHSLYRTFVPAMTAIHGPPITAPVVCTRKRRLEDDERQSIPSVLQGEVA 643
A A+ P ++ T P M ++ G P P + S S QG A
Sbjct: 383 ASQAHTNFPQMSNPGQFT-APQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPA 441
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 100 bits (248), Expect = 6e-21
Identities = 93/248 (37%), Positives = 112/248 (45%), Gaps = 39/248 (15%)
Query: 97 AGIGMPPRGPGQSLGGMGSLGAMGQPMSLS--GQPPPGTSGMAPHS-------------- 140
A + PP+ G S G L ++ QP + QP P T P +
Sbjct: 394 ATVQPPPQAAGSS-NQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQG 452
Query: 141 MAVVSTATPQTQLQLQQVALQQQQQQQQFQ--QQQQAALQQQQQQQQQQQFQAQQSAMQQ 198
+ + ATPQ Q QQ+ L+QQQQQQQ QQQ A QQQQ Q QQFQA A QQ
Sbjct: 453 LPAQAQATPQHQ---QQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQ 509
Query: 199 QFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQ 258
A Q + Q QQ L++ +Q QQQ QQQQQQ Q L QQ QQ QQ
Sbjct: 510 PAIA----QFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQ 565
Query: 259 QQQQALQAQPPIQQPPMQQPQPPPSQ--ALPQQLQQMHHTQHHQPPPQPQQPPVAQNQP- 315
+ A QP Q P PQP P+Q A+ ++Q QP Q PP Q Q
Sbjct: 566 KPTMAAGQQP--QPQPAAAPQPAPAQEPAIQAPVRQ-------QPKVQTTPPPAVQGQKV 616
Query: 316 -SQLPPQS 322
S PP S
Sbjct: 617 GSLTPPSS 624
Score = 87.4 bits (215), Expect = 4e-17
Identities = 100/344 (29%), Positives = 128/344 (37%), Gaps = 77/344 (22%)
Query: 128 QPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQ 187
QPPP +G + + S P+ Q Q Q Q +Q Q QQ Q Q
Sbjct: 397 QPPPQAAGSSNQPGLLASVPQPKPQ-----APPSQPLPQTQAKQPQAPPTPQQTPSTQAQ 451
Query: 188 QFQAQ-QSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQL-------- 238
AQ Q+ Q Q Q ++QQQQ QQ QQ +Q QQQ Q QQ Q
Sbjct: 452 GLPAQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQ-QQQAQTQQFQAVHPATQQP 510
Query: 239 --------------QRIAQLQLQQQQQQQQQQQQQ-------QQQALQAQPPIQQPPM-- 275
Q++ Q QQQQQQQQQQQQQ QQQ + Q +QQ P
Sbjct: 511 AIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMA 570
Query: 276 --QQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQA 333
QQPQP P+ A P P P Q P Q Q P T P Q Q
Sbjct: 571 AGQQPQPQPAAA---------------PQPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQK 615
Query: 334 LPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPML 393
+ G + PP P+ Q+ + GV S+S+ +L
Sbjct: 616 V-GSL-----------------TPPSSPKTQRAGHRRILSDVTHSAVFGVPASKST-QLL 656
Query: 394 SSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSP 437
+ + + +S P SP+ Q Q N S G +P
Sbjct: 657 QAAAAEASLNKSKSATTTPSGSPRTSQ---QNVYNPSEGSTWNP 697
Score = 63.2 bits (152), Expect = 9e-10
Identities = 68/235 (28%), Positives = 90/235 (38%), Gaps = 26/235 (11%)
Query: 245 QLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQ--PPPSQALPQQLQQMHHTQHHQPP 302
Q + Q Q Q Q + QA P QQ P Q Q P +QA PQ QQ+ Q Q
Sbjct: 417 QPKPQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQ- 475
Query: 303 PQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQ 362
QQPP AQ QP+ Q Q QAQ Q ++ + P + Q P V
Sbjct: 476 ---QQPPPAQQQPAGTFYQQQ------QAQTQQFQAVHPA-----TQQPAIAQFPVVSQG 521
Query: 363 VQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPS 422
QQQ Q Q Q Q L++ QQ+ T Q+ +P+ GQ
Sbjct: 522 GSQQQLMQNFYQQQQQ-----QQQQQQQQQLATALHQQQLMTQQAALQQ-KPTMAAGQ-- 573
Query: 423 SQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSS 477
QP ++ P P+P+ +P Q V P G L P +P +
Sbjct: 574 -QPQPQPAAAPQPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPSSPKT 627
Score = 47.4 bits (111), Expect = 5e-05
Identities = 41/188 (21%), Positives = 72/188 (38%), Gaps = 3/188 (1%)
Query: 318 LPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQ 377
L P +P + Q ++L + P+ V+ + + P +P + A +T A+
Sbjct: 294 LEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLP-EPVKASEAAAKKTQPKAR 352
Query: 378 MVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSP 437
+ P + +++S+ P GQ P +P P +P+ P S P
Sbjct: 353 LTDP-IPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGL 411
Query: 438 SSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLK 497
+ +P P PQ S +T P P TP + + + + QQ L LK
Sbjct: 412 LASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQL-FLK 470
Query: 498 QLSKYIEP 505
Q + +P
Sbjct: 471 QQQQQQQP 478
>gi|226246533 TOX high mobility group box family member 3 isoform 2
[Homo sapiens]
Length = 571
Score = 99.4 bits (246), Expect = 1e-20
Identities = 72/155 (46%), Positives = 83/155 (53%), Gaps = 24/155 (15%)
Query: 147 ATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQ 206
+ P TQ+ ++Q QQ Q Q QQQQQ QQQQQ QQ QQ Q QQ M QQ
Sbjct: 421 SAPSTQVS---PSVQTQQHQMQLQQQQQ---QQQQQMQQMQQQQLQQHQMHQQI------ 468
Query: 207 QQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQL-QRIAQLQLQQQQQQQQQQQQQQQQALQ 265
QQQ QQQH H QQ +QQQQQ L Q+I Q QLQQQ QQ+ Q QQ Q Q
Sbjct: 469 -----QQQMQQQH---FQHHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQ 520
Query: 266 AQP-PIQQPPM--QQPQPPPSQALPQQLQQMHHTQ 297
+QP P Q P+ Q P P+ PQ Q H +Q
Sbjct: 521 SQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQ 555
Score = 97.1 bits (240), Expect = 5e-20
Identities = 73/163 (44%), Positives = 81/163 (49%), Gaps = 19/163 (11%)
Query: 135 GMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQS 194
G AP + S T Q Q+QLQQ QQQQQ QQ QQQQ Q QQ QQQ Q Q Q
Sbjct: 420 GSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQH 479
Query: 195 AMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQ 254
MQQ Q QQQQ LQQQ NQQQ+QQQ QQ ++ QLQ Q Q Q
Sbjct: 480 HMQQHLQ---QQQQHLQQQ------------INQQQLQQQLQQRLQLQQLQ-HMQHQSQP 523
Query: 255 QQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQ 297
+Q A Q PI P + PQ P SQ Q+Q TQ
Sbjct: 524 SPRQHSPVASQITSPI--PAIGSPQ-PASQQHQSQIQSQTQTQ 563
Score = 89.4 bits (220), Expect = 1e-17
Identities = 65/160 (40%), Positives = 73/160 (45%), Gaps = 28/160 (17%)
Query: 183 QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIA 242
Q QQ Q Q QQ QQQ QQQQQ+QQ QQQQ ++H Q QQQ+QQQ Q
Sbjct: 432 QTQQHQMQLQQ---QQQ-----QQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQ 483
Query: 243 QLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPP 302
LQ QQQ QQQ QQQ QQ LQ + QLQQ+ H QH P
Sbjct: 484 HLQQQQQHLQQQINQQQLQQQLQQR--------------------LQLQQLQHMQHQSQP 523
Query: 303 PQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342
Q PVA S +P QP Q Q+ TQ
Sbjct: 524 SPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQ 563
Score = 63.2 bits (152), Expect = 9e-10
Identities = 55/151 (36%), Positives = 67/151 (44%), Gaps = 16/151 (10%)
Query: 230 QIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQ 289
Q QQ Q QLQ QQQQQQQQQ QQ QQQ LQ QQ Q Q + Q
Sbjct: 432 QTQQHQMQLQ-------QQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQH 484
Query: 290 LQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVR 349
LQQ QH Q QQ Q Q Q Q Q + Q+Q P Q P +
Sbjct: 485 LQQQQ--QHLQQQINQQQ---LQQQLQQRLQLQQLQHMQHQSQPSPRQ---HSPVASQIT 536
Query: 350 APMVVQQPPVQPQVQQQQTAVQTAQAAQMVA 380
+P+ P QP QQ Q+ +Q+ Q+++
Sbjct: 537 SPIPAIGSP-QPASQQHQSQIQSQTQTQVLS 566
Score = 42.7 bits (99), Expect = 0.001
Identities = 101/471 (21%), Positives = 160/471 (33%), Gaps = 68/471 (14%)
Query: 6 QETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIH 65
Q D S + LV Q GV HS +SH + +D SL+ R I+H
Sbjct: 104 QSLDLPSITISRNLVEQ-------DGVLHSSGLHMDQSHTQVSQYRQDP--SLIMRSIVH 154
Query: 66 FRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRG---PGQSLGGMGSLGAMGQP 122
D A+ S M Q T + +A +G+ G P S S A P
Sbjct: 155 MTD-------AARSGVMPPAQLTTINQSQLSAQLGLNLGGASMPHTSPSPPASKSATPSP 207
Query: 123 MSLSGQ----------------PPPGTSGMAPHSMAVVSTATPQTQLQLQ-------QVA 159
S + P G P PQ + Q A
Sbjct: 208 SSSINEEDADEANRAIGEKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAA 267
Query: 160 LQQQQQQQQFQQQQQ--AALQQQQQQQQQQQFQAQQSAMQQQF-QAVVQQQQQLQQQQQQ 216
++ Q F + + A++ ++Q+Q ++ + A ++++ +A+ + L +
Sbjct: 268 IKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAA 327
Query: 217 QQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQ---QQQQQQQQQQQQQALQAQPPIQQP 273
+ + QQ + + L Q Q QQ +++ +P +
Sbjct: 328 ESAEAQTIRSVQQTLASTNLTSSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRL 387
Query: 274 PMQQ-------PQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQP 326
PM Q PS + M T P Q P Q Q Q+ Q Q Q
Sbjct: 388 PMNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAP-STQVSPSVQTQQHQMQLQQQQQQ 446
Query: 327 LVSQAQALPGQMLYTQPPLKFVRAPMVVQ------QPPVQPQVQQQQTAVQTAQAAQMVA 380
Q Q + Q L + ++ M Q Q +Q Q Q Q + Q Q +
Sbjct: 447 QQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQ 506
Query: 381 PGVQVSQ-SSLPMLSSPSPGQQ--VQTPQSMPPPPQPSPQPGQPSSQPNSN 428
+Q+ Q + S PSP Q V + + P P SP QP+SQ + +
Sbjct: 507 QRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAIGSP---QPASQQHQS 554
>gi|226054295 TOX high mobility group box family member 3 isoform 1
[Homo sapiens]
Length = 576
Score = 99.4 bits (246), Expect = 1e-20
Identities = 72/155 (46%), Positives = 83/155 (53%), Gaps = 24/155 (15%)
Query: 147 ATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQ 206
+ P TQ+ ++Q QQ Q Q QQQQQ QQQQQ QQ QQ Q QQ M QQ
Sbjct: 426 SAPSTQVS---PSVQTQQHQMQLQQQQQ---QQQQQMQQMQQQQLQQHQMHQQI------ 473
Query: 207 QQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQL-QRIAQLQLQQQQQQQQQQQQQQQQALQ 265
QQQ QQQH H QQ +QQQQQ L Q+I Q QLQQQ QQ+ Q QQ Q Q
Sbjct: 474 -----QQQMQQQH---FQHHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQ 525
Query: 266 AQP-PIQQPPM--QQPQPPPSQALPQQLQQMHHTQ 297
+QP P Q P+ Q P P+ PQ Q H +Q
Sbjct: 526 SQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQ 560
Score = 97.1 bits (240), Expect = 5e-20
Identities = 73/163 (44%), Positives = 81/163 (49%), Gaps = 19/163 (11%)
Query: 135 GMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQS 194
G AP + S T Q Q+QLQQ QQQQQ QQ QQQQ Q QQ QQQ Q Q Q
Sbjct: 425 GSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQH 484
Query: 195 AMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQ 254
MQQ Q QQQQ LQQQ NQQQ+QQQ QQ ++ QLQ Q Q Q
Sbjct: 485 HMQQHLQ---QQQQHLQQQ------------INQQQLQQQLQQRLQLQQLQ-HMQHQSQP 528
Query: 255 QQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQ 297
+Q A Q PI P + PQ P SQ Q+Q TQ
Sbjct: 529 SPRQHSPVASQITSPI--PAIGSPQ-PASQQHQSQIQSQTQTQ 568
Score = 89.4 bits (220), Expect = 1e-17
Identities = 65/160 (40%), Positives = 73/160 (45%), Gaps = 28/160 (17%)
Query: 183 QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIA 242
Q QQ Q Q QQ QQQ QQQQQ+QQ QQQQ ++H Q QQQ+QQQ Q
Sbjct: 437 QTQQHQMQLQQ---QQQ-----QQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQ 488
Query: 243 QLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPP 302
LQ QQQ QQQ QQQ QQ LQ + QLQQ+ H QH P
Sbjct: 489 HLQQQQQHLQQQINQQQLQQQLQQR--------------------LQLQQLQHMQHQSQP 528
Query: 303 PQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342
Q PVA S +P QP Q Q+ TQ
Sbjct: 529 SPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQ 568
Score = 63.2 bits (152), Expect = 9e-10
Identities = 55/151 (36%), Positives = 67/151 (44%), Gaps = 16/151 (10%)
Query: 230 QIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQ 289
Q QQ Q QLQ QQQQQQQQQ QQ QQQ LQ QQ Q Q + Q
Sbjct: 437 QTQQHQMQLQ-------QQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQH 489
Query: 290 LQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVR 349
LQQ QH Q QQ Q Q Q Q Q + Q+Q P Q P +
Sbjct: 490 LQQQQ--QHLQQQINQQQ---LQQQLQQRLQLQQLQHMQHQSQPSPRQ---HSPVASQIT 541
Query: 350 APMVVQQPPVQPQVQQQQTAVQTAQAAQMVA 380
+P+ P QP QQ Q+ +Q+ Q+++
Sbjct: 542 SPIPAIGSP-QPASQQHQSQIQSQTQTQVLS 571
Score = 42.7 bits (99), Expect = 0.001
Identities = 101/471 (21%), Positives = 160/471 (33%), Gaps = 68/471 (14%)
Query: 6 QETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIH 65
Q D S + LV Q GV HS +SH + +D SL+ R I+H
Sbjct: 109 QSLDLPSITISRNLVEQ-------DGVLHSSGLHMDQSHTQVSQYRQDP--SLIMRSIVH 159
Query: 66 FRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRG---PGQSLGGMGSLGAMGQP 122
D A+ S M Q T + +A +G+ G P S S A P
Sbjct: 160 MTD-------AARSGVMPPAQLTTINQSQLSAQLGLNLGGASMPHTSPSPPASKSATPSP 212
Query: 123 MSLSGQ----------------PPPGTSGMAPHSMAVVSTATPQTQLQLQ-------QVA 159
S + P G P PQ + Q A
Sbjct: 213 SSSINEEDADEANRAIGEKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAA 272
Query: 160 LQQQQQQQQFQQQQQ--AALQQQQQQQQQQQFQAQQSAMQQQF-QAVVQQQQQLQQQQQQ 216
++ Q F + + A++ ++Q+Q ++ + A ++++ +A+ + L +
Sbjct: 273 IKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAA 332
Query: 217 QQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQ---QQQQQQQQQQQQQALQAQPPIQQP 273
+ + QQ + + L Q Q QQ +++ +P +
Sbjct: 333 ESAEAQTIRSVQQTLASTNLTSSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRL 392
Query: 274 PMQQ-------PQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQP 326
PM Q PS + M T P Q P Q Q Q+ Q Q Q
Sbjct: 393 PMNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAP-STQVSPSVQTQQHQMQLQQQQQQ 451
Query: 327 LVSQAQALPGQMLYTQPPLKFVRAPMVVQ------QPPVQPQVQQQQTAVQTAQAAQMVA 380
Q Q + Q L + ++ M Q Q +Q Q Q Q + Q Q +
Sbjct: 452 QQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQ 511
Query: 381 PGVQVSQ-SSLPMLSSPSPGQQ--VQTPQSMPPPPQPSPQPGQPSSQPNSN 428
+Q+ Q + S PSP Q V + + P P SP QP+SQ + +
Sbjct: 512 QRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAIGSP---QPASQQHQS 559
>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
Length = 1312
Score = 96.7 bits (239), Expect = 7e-20
Identities = 102/412 (24%), Positives = 171/412 (41%), Gaps = 53/412 (12%)
Query: 115 SLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQ--------- 165
S G G+P S+ P G S + + + ++ QQ LQQQQQ
Sbjct: 332 SHGEEGEPSSIMNVP--GESTLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKH 389
Query: 166 ---------QQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQ 216
++Q +++++ QQ+++++Q++ + +Q + QA+ +++++ Q +++Q
Sbjct: 390 LLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQ 449
Query: 217 QQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL--QAQPPIQQPP 274
+ +L Q Q + Q+Q Q + LQQQQQQQQ Q+QQQQQ L +P
Sbjct: 450 EYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGR 509
Query: 275 MQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ------QPPVAQNQPSQLPPQSQTQPLV 328
P P+ A + + + Q + P + + +PP+ Q P P SQT P+
Sbjct: 510 GMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQ 569
Query: 329 S--QAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVS 386
+ Q P + L QP P P P A A A G +
Sbjct: 570 RPVEPQEGPHKSLQDQPTRNLAAFPASHDPDPAIP-----------APTATPSARGAVIR 618
Query: 387 QSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQ-PGQPSSQPNSNVSSGPAPSPSSFLPSPS 445
Q+S P +S PG P + P + P+ P + SS + +SG S +
Sbjct: 619 QNSDP--TSEGPGPSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRAR 676
Query: 446 PQPS-------QSPVTARTPQNFSVPS--PGPLNTPVNPSSVMSPAGSSQAE 488
P+ + Q TP+ P+ PGP N NP S G +++
Sbjct: 677 PRSNSAWQIYLQRRAERGTPKPPGPPAQPPGPPNASSNPDLRRSDPGWERSD 728
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 95.1 bits (235), Expect = 2e-19
Identities = 121/415 (29%), Positives = 162/415 (39%), Gaps = 62/415 (14%)
Query: 102 PPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSM--AVVSTATPQTQLQLQQVA 159
P G + + M + A+ P S QPP S A + + S ++PQ Q Q+ +
Sbjct: 1993 PMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNIL 2052
Query: 160 LQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQ--------------FQA--- 202
Q F +Q+ A Q Q Q Q MQ Q QA
Sbjct: 2053 KSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVP 2112
Query: 203 ---VVQQQQQLQQQQQQQQHLIKL---HHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQ 256
V QQQ + Q Q L + H+ N + Q +++ R LQ QQQQQQQQQQ
Sbjct: 2113 RPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQ 2172
Query: 257 QQQQQQ--ALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQ 314
QQQQQQ A A QQPQ P P +QQ Q H P +A Q
Sbjct: 2173 QQQQQQGSAGMAGGMAGHGQFQQPQGP--GGYPPAMQQQQRMQQHLPLQGSSMGQMAA-Q 2229
Query: 315 PSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQ--------PPVQPQVQQQ 366
QL Q PG + P ++ ++QQ P QP
Sbjct: 2230 MGQLGQMGQ-----------PGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSP 2278
Query: 367 QTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSP--QPGQPSSQ 424
Q + + Q PG Q++ S + SP+P Q + PQS PP PSP QP QPS
Sbjct: 2279 QQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPR-PQSQPPHSSPSPRIQP-QPSPH 2336
Query: 425 PNSNVSSGPAPSPSSFLPSPSPQ-----PSQSPVTARTPQNFSVPSPGPLNTPVN 474
S + P P + + S Q P QS A PQ + PS L++ ++
Sbjct: 2337 HVSPQTGSPHPGLAVTMASSIDQGHLGNPEQS---AMLPQ-LNTPSRSALSSELS 2387
Score = 78.6 bits (192), Expect = 2e-14
Identities = 112/415 (26%), Positives = 150/415 (36%), Gaps = 51/415 (12%)
Query: 106 PGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQ- 164
PG++ GMG+ G+ P+SL+ P SG SM Q QQ L QQQ
Sbjct: 1945 PGRT--GMGTPGSQMAPVSLNVPRPNQVSGPVMPSM---------PPGQWQQAPLPQQQP 1993
Query: 165 ----QQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHL 220
+ Q QAA+ + Q SA+Q + + + QQQQQ ++
Sbjct: 1994 MPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTL--KSPSSPQQQQQVLNI 2051
Query: 221 IKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQ-----QPPM 275
+K + Q +Q+ Q +Q Q Q Q Q Q + QP +Q Q +
Sbjct: 2052 LKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGV 2111
Query: 276 QQPQPPPSQAL-----PQQLQQMHHTQHHQPPPQPQQPPV------------AQNQPSQL 318
+P PP Q PQ H P P Q Q Q
Sbjct: 2112 PRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQ 2171
Query: 319 PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQ-----QTAVQTA 373
Q Q Q A + G + QP P + QQ +Q + Q Q A Q
Sbjct: 2172 QQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMG 2231
Query: 374 QAAQMVAPGVQV-SQSSLPMLSSPSPGQQVQTPQSMPPPPQP---SPQPGQPSSQPNSNV 429
Q QM PG+ S ++ QQ Q Q + P QP SPQ S QP ++
Sbjct: 2232 QLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASH 2291
Query: 430 SSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGS 484
G + S SP P QSP P + S PSP P +P V GS
Sbjct: 2292 LPGQQIATSLSNQVRSPAPVQSPRPQSQPPH-SSPSPRIQPQP-SPHHVSPQTGS 2344
Score = 70.1 bits (170), Expect = 7e-12
Identities = 70/240 (29%), Positives = 94/240 (39%), Gaps = 33/240 (13%)
Query: 245 QLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALP-QQLQQMHHTQHHQPPP 303
+L+QQQ Q + QQ Q + A + P QQ P P+ A P QQ Q QPP
Sbjct: 1811 KLRQQQIQHRLQQAQLMRRRMATMNTRNVP-QQSLPSPTSAPPGTPTQQPSTPQTPQPPA 1869
Query: 304 QPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQV 363
QPQ PV+ + P+ P ++TQP + + P + PP V ++ +
Sbjct: 1870 QPQPSPVSMS-PAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREA 1928
Query: 364 QQQQTAVQT-------AQAAQMVAPGVQVSQSSL----------PMLSSPSPG--QQVQT 404
QQQQ + M PG Q++ SL P++ S PG QQ
Sbjct: 1929 QQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPL 1988
Query: 405 PQSMPPPPQPSP-----------QPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPV 453
PQ P P P P P PS QP ++S L SPS Q V
Sbjct: 1989 PQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQV 2048
Score = 60.8 bits (146), Expect = 4e-09
Identities = 94/412 (22%), Positives = 143/412 (34%), Gaps = 43/412 (10%)
Query: 38 SKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAA 97
+K +E ++ A +RDEY L+A I + +K ++ + L + PA GA
Sbjct: 595 AKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRL-HKQGILGNQPALPAPGAQ 653
Query: 98 GIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGM-APHSMAVVSTATPQTQLQLQ 156
+P P + G P+SL + GM + + M++ + PQ + +
Sbjct: 654 PPVIPQAQPVRPPNG---------PLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPR 704
Query: 157 QVA-LQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQ 215
+ + Q A+ + Q A + M Q A Q Q L Q Q
Sbjct: 705 AASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPA---QSQFLPQNQF 761
Query: 216 QQQHLIKLHHQNQQQIQQQQQQLQR-IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPP 274
+ Q Q ++Q Q+ Q + PP+ Q P
Sbjct: 762 PSS-------SGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSP 814
Query: 275 MQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQP-----PVAQN------QPSQLPPQSQ 323
+ P PPP+ H T PPQP P PV+ + P +P +Q
Sbjct: 815 L-HPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQ 873
Query: 324 TQ--PLV---SQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAV-QTAQAAQ 377
TQ P V +QAQ P QPP V P QQ P Q T + Q A +
Sbjct: 874 TQSTPTVQAAAQAQVTPQPQTPVQPP--SVATPQSSQQQPTPVHAQPPGTPLSQAAASID 931
Query: 378 MVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNV 429
P S+ P P V ++ P PG+ +P S +
Sbjct: 932 NRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEM 983
Score = 60.5 bits (145), Expect = 6e-09
Identities = 75/299 (25%), Positives = 111/299 (37%), Gaps = 68/299 (22%)
Query: 245 QLQQQQQQQQQQQQQQQQALQAQPPIQQP-------PMQQPQPPPSQALPQQLQQMHHTQ 297
++Q++ +++++ + +Q L QP + P P QP PP+ L + +M +Q
Sbjct: 622 KIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQ 681
Query: 298 -----------HHQPPPQPQQPPVAQNQ------------------PSQLPPQ-----SQ 323
+ Q P P P A PS++P +
Sbjct: 682 GMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAH 741
Query: 324 TQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTA---------VQTAQ 374
T +++QA A + Q P + + QPP Q V Q Q + Q
Sbjct: 742 TNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQ 801
Query: 375 AAQMVAPGVQVSQSSLPMLSSPS------PGQQVQTPQSMPPP-PQPSPQPGQPSSQPNS 427
A+Q+ P V+QS L P+ P Q TP M PP P QP P S
Sbjct: 802 ASQLPCP--PVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVS---- 855
Query: 428 NVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQ 486
SSG P+P+ + Q +P Q P P TPV P SV +P S Q
Sbjct: 856 --SSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQ 909
Score = 55.1 bits (131), Expect = 2e-07
Identities = 83/356 (23%), Positives = 132/356 (37%), Gaps = 31/356 (8%)
Query: 260 QQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLP 319
Q ++ + P + P + PQPP Q PQ Q P + S
Sbjct: 714 QMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPS-SSGAMSVGM 772
Query: 320 PQSQTQPLVSQAQ----ALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQA 375
Q Q VSQ Q ALP + P + P V Q P + P TA
Sbjct: 773 GQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSP-LHPTPPPASTAAGMPSL 831
Query: 376 AQMVAPGVQV------SQSSLPMLSS-----PSPGQQVQTPQSMPPPPQPSPQPGQPSSQ 424
PG+ +Q S P+ SS P+PG Q+ P + Q + Q
Sbjct: 832 QHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQ 891
Query: 425 PNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGS 484
P + V +P S P+P +Q P T + S+ + P PSSV S +
Sbjct: 892 PQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVP-----TPSSVASAETN 946
Query: 485 SQ--AEEQQYLD-KLKQLSKYIEPLRRMINKIDKNEDRKKDL---SKMKSLLDIL---TD 535
SQ + L+ K + ++ EP ++E ++DL S++K DI ++
Sbjct: 947 SQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSE 1006
Query: 536 PSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRS 591
P + K K E+ E+ + + P P K+ + + L A++ + +
Sbjct: 1007 PMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEA 1062
Score = 53.1 bits (126), Expect = 9e-07
Identities = 40/108 (37%), Positives = 52/108 (48%), Gaps = 16/108 (14%)
Query: 360 QPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPG---QQVQTPQSMPPPPQPSP 416
Q Q+Q + Q + V Q SLP +S PG QQ TPQ+ PP QP P
Sbjct: 1814 QQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQP 1873
Query: 417 QP------GQPS---SQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTA 455
P G PS +QP + VS+G P+S +P+P P P+Q P A
Sbjct: 1874 SPVSMSPAGFPSVARTQPPTTVSTG---KPTSQVPAP-PPPAQPPPAA 1917
Score = 52.8 bits (125), Expect = 1e-06
Identities = 71/287 (24%), Positives = 104/287 (36%), Gaps = 66/287 (22%)
Query: 202 AVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQ 261
A V+ +Q++++ QQQQHL +++ N
Sbjct: 1916 AAVEAARQIEREAQQQQHLYRVNINN-----------------------------SMPPG 1946
Query: 262 QALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQ 321
+ P Q P+ P P+Q + M PP Q QQ P+ Q QP P
Sbjct: 1947 RTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSM-------PPGQWQQAPLPQQQPMPGLP- 1998
Query: 322 SQTQPLVS-QAQALPG--QMLYTQPPLKFVRAPMVVQ------QPPVQPQVQQQQTAVQT 372
+P++S QAQA +M QPP +P +Q + P PQ QQQ +
Sbjct: 1999 ---RPVISMQAQAAVAGPRMPSVQPPRSI--SPSALQDLLRTLKSPSSPQQQQQVLNILK 2053
Query: 373 AQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSG 432
+ M A + Q + +++ PG Q Q P QP P Q S N N
Sbjct: 2054 SNPQLMAA---FIKQRTAKYVAN-QPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLN---- 2105
Query: 433 PAPSPSSFLPSPSPQPSQSPVTARTPQ----NFSVPSPGPLNTPVNP 475
+ + +P P P Q + PQ N P P +NP
Sbjct: 2106 ---AMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNP 2149
Score = 43.1 bits (100), Expect = 0.001
Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 22/142 (15%)
Query: 359 VQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQP 418
++ +++QQQ + QA M ++ ++P S PSP S P
Sbjct: 1808 IKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSP---------------TSAPP 1852
Query: 419 GQPSSQPNS----NVSSGPAPSPSSFLPS--PSPQPSQSPVTARTPQNFS-VPSPGPLNT 471
G P+ QP++ + P PSP S P+ PS +Q P T T + S VP+P P
Sbjct: 1853 GTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQ 1912
Query: 472 PVNPSSVMSPAGSSQAEEQQYL 493
P + + +A++QQ+L
Sbjct: 1913 PPPAAVEAARQIEREAQQQQHL 1934
Score = 38.1 bits (87), Expect = 0.030
Identities = 56/271 (20%), Positives = 82/271 (30%), Gaps = 22/271 (8%)
Query: 95 GAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPH--SMAVVSTATPQTQ 152
G AG+ G +G G+ GQP S +G P G +G+ P S + + P
Sbjct: 252 GHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFP 311
Query: 153 LQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQ 212
++ ++ Q Q Q + ++ QQ + + Q ++
Sbjct: 312 TDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLLLHAHKCQRRE 371
Query: 213 QQQQQQHLIKLHH-------QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQ 265
Q + L H N Q + Q I Q QQ A
Sbjct: 372 QANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQAILGSPASGIQNTIGSVGTGQQNATS 431
Query: 266 AQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQ---------NQPS 316
P P + + LP Q Q P QP QP Q N P
Sbjct: 432 LSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPM 491
Query: 317 QLP----PQSQTQPLVSQAQALPGQMLYTQP 343
+P Q P + ALP + T P
Sbjct: 492 NIPAGGITTDQQPPNLISESALPTSLGATNP 522
Score = 30.4 bits (67), Expect = 6.3
Identities = 50/215 (23%), Positives = 74/215 (34%), Gaps = 29/215 (13%)
Query: 269 PIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQN------QPSQLPPQS 322
P Q P P SQAL Q Q+ P P + N P L S
Sbjct: 134 PKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTHPGLLNSNS 193
Query: 323 Q----TQPLVSQAQALPGQ-----------MLYTQPPLKFVRAPMVVQQ-PPVQPQVQQQ 366
Q QAQ + G M Y P ++ + ++ + V PQ+
Sbjct: 194 GHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQM-TG 252
Query: 367 QTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQV----QTPQSMPPPPQPSPQPGQPS 422
+ TAQA M G+ + S S + GQ + PQ + P P+
Sbjct: 253 HAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFPT 312
Query: 423 SQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTART 457
N++V++ P+ S S P+Q+ T T
Sbjct: 313 DIKNTSVTN--VPNMSQMQTSVGIVPTQAIATGPT 345
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 95.1 bits (235), Expect = 2e-19
Identities = 121/415 (29%), Positives = 162/415 (39%), Gaps = 62/415 (14%)
Query: 102 PPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSM--AVVSTATPQTQLQLQQVA 159
P G + + M + A+ P S QPP S A + + S ++PQ Q Q+ +
Sbjct: 2031 PMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNIL 2090
Query: 160 LQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQ--------------FQA--- 202
Q F +Q+ A Q Q Q Q MQ Q QA
Sbjct: 2091 KSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVP 2150
Query: 203 ---VVQQQQQLQQQQQQQQHLIKL---HHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQ 256
V QQQ + Q Q L + H+ N + Q +++ R LQ QQQQQQQQQQ
Sbjct: 2151 RPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQ 2210
Query: 257 QQQQQQ--ALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQ 314
QQQQQQ A A QQPQ P P +QQ Q H P +A Q
Sbjct: 2211 QQQQQQGSAGMAGGMAGHGQFQQPQGP--GGYPPAMQQQQRMQQHLPLQGSSMGQMAA-Q 2267
Query: 315 PSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQ--------PPVQPQVQQQ 366
QL Q PG + P ++ ++QQ P QP
Sbjct: 2268 MGQLGQMGQ-----------PGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSP 2316
Query: 367 QTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSP--QPGQPSSQ 424
Q + + Q PG Q++ S + SP+P Q + PQS PP PSP QP QPS
Sbjct: 2317 QQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPR-PQSQPPHSSPSPRIQP-QPSPH 2374
Query: 425 PNSNVSSGPAPSPSSFLPSPSPQ-----PSQSPVTARTPQNFSVPSPGPLNTPVN 474
S + P P + + S Q P QS A PQ + PS L++ ++
Sbjct: 2375 HVSPQTGSPHPGLAVTMASSIDQGHLGNPEQS---AMLPQ-LNTPSRSALSSELS 2425
Score = 78.6 bits (192), Expect = 2e-14
Identities = 112/415 (26%), Positives = 150/415 (36%), Gaps = 51/415 (12%)
Query: 106 PGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQ- 164
PG++ GMG+ G+ P+SL+ P SG SM Q QQ L QQQ
Sbjct: 1983 PGRT--GMGTPGSQMAPVSLNVPRPNQVSGPVMPSM---------PPGQWQQAPLPQQQP 2031
Query: 165 ----QQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHL 220
+ Q QAA+ + Q SA+Q + + + QQQQQ ++
Sbjct: 2032 MPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTL--KSPSSPQQQQQVLNI 2089
Query: 221 IKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQ-----QPPM 275
+K + Q +Q+ Q +Q Q Q Q Q Q + QP +Q Q +
Sbjct: 2090 LKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGV 2149
Query: 276 QQPQPPPSQAL-----PQQLQQMHHTQHHQPPPQPQQPPV------------AQNQPSQL 318
+P PP Q PQ H P P Q Q Q
Sbjct: 2150 PRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQ 2209
Query: 319 PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQ-----QTAVQTA 373
Q Q Q A + G + QP P + QQ +Q + Q Q A Q
Sbjct: 2210 QQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMG 2269
Query: 374 QAAQMVAPGVQV-SQSSLPMLSSPSPGQQVQTPQSMPPPPQP---SPQPGQPSSQPNSNV 429
Q QM PG+ S ++ QQ Q Q + P QP SPQ S QP ++
Sbjct: 2270 QLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASH 2329
Query: 430 SSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGS 484
G + S SP P QSP P + S PSP P +P V GS
Sbjct: 2330 LPGQQIATSLSNQVRSPAPVQSPRPQSQPPH-SSPSPRIQPQP-SPHHVSPQTGS 2382
Score = 70.1 bits (170), Expect = 7e-12
Identities = 70/240 (29%), Positives = 94/240 (39%), Gaps = 33/240 (13%)
Query: 245 QLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALP-QQLQQMHHTQHHQPPP 303
+L+QQQ Q + QQ Q + A + P QQ P P+ A P QQ Q QPP
Sbjct: 1849 KLRQQQIQHRLQQAQLMRRRMATMNTRNVP-QQSLPSPTSAPPGTPTQQPSTPQTPQPPA 1907
Query: 304 QPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQV 363
QPQ PV+ + P+ P ++TQP + + P + PP V ++ +
Sbjct: 1908 QPQPSPVSMS-PAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREA 1966
Query: 364 QQQQTAVQT-------AQAAQMVAPGVQVSQSSL----------PMLSSPSPG--QQVQT 404
QQQQ + M PG Q++ SL P++ S PG QQ
Sbjct: 1967 QQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPL 2026
Query: 405 PQSMPPPPQPSP-----------QPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPV 453
PQ P P P P P PS QP ++S L SPS Q V
Sbjct: 2027 PQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQV 2086
Score = 60.8 bits (146), Expect = 4e-09
Identities = 94/412 (22%), Positives = 143/412 (34%), Gaps = 43/412 (10%)
Query: 38 SKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAA 97
+K +E ++ A +RDEY L+A I + +K ++ + L + PA GA
Sbjct: 633 AKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRL-HKQGILGNQPALPAPGAQ 691
Query: 98 GIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGM-APHSMAVVSTATPQTQLQLQ 156
+P P + G P+SL + GM + + M++ + PQ + +
Sbjct: 692 PPVIPQAQPVRPPNG---------PLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPR 742
Query: 157 QVA-LQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQ 215
+ + Q A+ + Q A + M Q A Q Q L Q Q
Sbjct: 743 AASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPA---QSQFLPQNQF 799
Query: 216 QQQHLIKLHHQNQQQIQQQQQQLQR-IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPP 274
+ Q Q ++Q Q+ Q + PP+ Q P
Sbjct: 800 PSS-------SGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSP 852
Query: 275 MQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQP-----PVAQN------QPSQLPPQSQ 323
+ P PPP+ H T PPQP P PV+ + P +P +Q
Sbjct: 853 L-HPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQ 911
Query: 324 TQ--PLV---SQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAV-QTAQAAQ 377
TQ P V +QAQ P QPP V P QQ P Q T + Q A +
Sbjct: 912 TQSTPTVQAAAQAQVTPQPQTPVQPP--SVATPQSSQQQPTPVHAQPPGTPLSQAAASID 969
Query: 378 MVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNV 429
P S+ P P V ++ P PG+ +P S +
Sbjct: 970 NRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEM 1021
Score = 60.5 bits (145), Expect = 6e-09
Identities = 75/299 (25%), Positives = 111/299 (37%), Gaps = 68/299 (22%)
Query: 245 QLQQQQQQQQQQQQQQQQALQAQPPIQQP-------PMQQPQPPPSQALPQQLQQMHHTQ 297
++Q++ +++++ + +Q L QP + P P QP PP+ L + +M +Q
Sbjct: 660 KIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQ 719
Query: 298 -----------HHQPPPQPQQPPVAQNQ------------------PSQLPPQ-----SQ 323
+ Q P P P A PS++P +
Sbjct: 720 GMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAH 779
Query: 324 TQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTA---------VQTAQ 374
T +++QA A + Q P + + QPP Q V Q Q + Q
Sbjct: 780 TNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQ 839
Query: 375 AAQMVAPGVQVSQSSLPMLSSPS------PGQQVQTPQSMPPP-PQPSPQPGQPSSQPNS 427
A+Q+ P V+QS L P+ P Q TP M PP P QP P S
Sbjct: 840 ASQLPCP--PVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVS---- 893
Query: 428 NVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQ 486
SSG P+P+ + Q +P Q P P TPV P SV +P S Q
Sbjct: 894 --SSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQ 947
Score = 55.1 bits (131), Expect = 2e-07
Identities = 83/356 (23%), Positives = 132/356 (37%), Gaps = 31/356 (8%)
Query: 260 QQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLP 319
Q ++ + P + P + PQPP Q PQ Q P + S
Sbjct: 752 QMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPS-SSGAMSVGM 810
Query: 320 PQSQTQPLVSQAQ----ALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQA 375
Q Q VSQ Q ALP + P + P V Q P + P TA
Sbjct: 811 GQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSP-LHPTPPPASTAAGMPSL 869
Query: 376 AQMVAPGVQV------SQSSLPMLSS-----PSPGQQVQTPQSMPPPPQPSPQPGQPSSQ 424
PG+ +Q S P+ SS P+PG Q+ P + Q + Q
Sbjct: 870 QHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQ 929
Query: 425 PNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGS 484
P + V +P S P+P +Q P T + S+ + P PSSV S +
Sbjct: 930 PQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVP-----TPSSVASAETN 984
Query: 485 SQ--AEEQQYLD-KLKQLSKYIEPLRRMINKIDKNEDRKKDL---SKMKSLLDIL---TD 535
SQ + L+ K + ++ EP ++E ++DL S++K DI ++
Sbjct: 985 SQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSE 1044
Query: 536 PSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRS 591
P + K K E+ E+ + + P P K+ + + L A++ + +
Sbjct: 1045 PMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEA 1100
Score = 53.1 bits (126), Expect = 9e-07
Identities = 40/108 (37%), Positives = 52/108 (48%), Gaps = 16/108 (14%)
Query: 360 QPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPG---QQVQTPQSMPPPPQPSP 416
Q Q+Q + Q + V Q SLP +S PG QQ TPQ+ PP QP P
Sbjct: 1852 QQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQP 1911
Query: 417 QP------GQPS---SQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTA 455
P G PS +QP + VS+G P+S +P+P P P+Q P A
Sbjct: 1912 SPVSMSPAGFPSVARTQPPTTVSTG---KPTSQVPAP-PPPAQPPPAA 1955
Score = 52.8 bits (125), Expect = 1e-06
Identities = 71/287 (24%), Positives = 104/287 (36%), Gaps = 66/287 (22%)
Query: 202 AVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQ 261
A V+ +Q++++ QQQQHL +++ N
Sbjct: 1954 AAVEAARQIEREAQQQQHLYRVNINN-----------------------------SMPPG 1984
Query: 262 QALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQ 321
+ P Q P+ P P+Q + M PP Q QQ P+ Q QP P
Sbjct: 1985 RTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSM-------PPGQWQQAPLPQQQPMPGLP- 2036
Query: 322 SQTQPLVS-QAQALPG--QMLYTQPPLKFVRAPMVVQ------QPPVQPQVQQQQTAVQT 372
+P++S QAQA +M QPP +P +Q + P PQ QQQ +
Sbjct: 2037 ---RPVISMQAQAAVAGPRMPSVQPPRSI--SPSALQDLLRTLKSPSSPQQQQQVLNILK 2091
Query: 373 AQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSG 432
+ M A + Q + +++ PG Q Q P QP P Q S N N
Sbjct: 2092 SNPQLMAA---FIKQRTAKYVAN-QPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLN---- 2143
Query: 433 PAPSPSSFLPSPSPQPSQSPVTARTPQ----NFSVPSPGPLNTPVNP 475
+ + +P P P Q + PQ N P P +NP
Sbjct: 2144 ---AMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNP 2187
Score = 43.1 bits (100), Expect = 0.001
Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 22/142 (15%)
Query: 359 VQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQP 418
++ +++QQQ + QA M ++ ++P S PSP S P
Sbjct: 1846 IKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSP---------------TSAPP 1890
Query: 419 GQPSSQPNS----NVSSGPAPSPSSFLPS--PSPQPSQSPVTARTPQNFS-VPSPGPLNT 471
G P+ QP++ + P PSP S P+ PS +Q P T T + S VP+P P
Sbjct: 1891 GTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQ 1950
Query: 472 PVNPSSVMSPAGSSQAEEQQYL 493
P + + +A++QQ+L
Sbjct: 1951 PPPAAVEAARQIEREAQQQQHL 1972
Score = 32.7 bits (73), Expect = 1.3
Identities = 61/311 (19%), Positives = 95/311 (30%), Gaps = 64/311 (20%)
Query: 95 GAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPH--------------- 139
G AG+ G +G G+ GQP S +G P G +G+ P
Sbjct: 252 GHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFP 311
Query: 140 ------------SMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQ 187
+M+ + T+ Q ++++ QQQ L + Q+++
Sbjct: 312 TDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLLLHAHKCQRRE 371
Query: 188 QFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQR---IAQL 244
Q + A ++ Q + H + +QI + R L
Sbjct: 372 QANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCL 431
Query: 245 QLQQQQQQQQQQQ-------------------QQQQQALQAQPPIQQPPMQQPQPPPSQA 285
L+ ++ QQ QQ +L PI MQ+ +
Sbjct: 432 PLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSSMQRAY--AALG 489
Query: 286 LPQQLQQMHHTQHHQPPPQPQQPPVAQ---------NQPSQLP----PQSQTQPLVSQAQ 332
LP Q Q P QP QP Q N P +P Q P +
Sbjct: 490 LPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISES 549
Query: 333 ALPGQMLYTQP 343
ALP + T P
Sbjct: 550 ALPTSLGATNP 560
Score = 30.4 bits (67), Expect = 6.3
Identities = 50/215 (23%), Positives = 74/215 (34%), Gaps = 29/215 (13%)
Query: 269 PIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQN------QPSQLPPQS 322
P Q P P SQAL Q Q+ P P + N P L S
Sbjct: 134 PKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTHPGLLNSNS 193
Query: 323 Q----TQPLVSQAQALPGQ-----------MLYTQPPLKFVRAPMVVQQ-PPVQPQVQQQ 366
Q QAQ + G M Y P ++ + ++ + V PQ+
Sbjct: 194 GHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQM-TG 252
Query: 367 QTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQV----QTPQSMPPPPQPSPQPGQPS 422
+ TAQA M G+ + S S + GQ + PQ + P P+
Sbjct: 253 HAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFPT 312
Query: 423 SQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTART 457
N++V++ P+ S S P+Q+ T T
Sbjct: 313 DIKNTSVTN--VPNMSQMQTSVGIVPTQAIATGPT 345
>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
Length = 1332
Score = 95.1 bits (235), Expect = 2e-19
Identities = 104/422 (24%), Positives = 179/422 (42%), Gaps = 53/422 (12%)
Query: 115 SLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQ--------- 165
S G G+P S+ P G S + + + ++ QQ LQQQQQ
Sbjct: 332 SHGEEGEPSSIMNVP--GESTLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKH 389
Query: 166 ---------QQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQ 216
++Q +++++ QQ+++++Q++ + +Q + QA+ +++++ Q +++Q
Sbjct: 390 LLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQ 449
Query: 217 QQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL--QAQPPIQQPP 274
+ +L Q Q + Q+Q Q + LQQQQQQQQ Q+QQQQQ L +P
Sbjct: 450 EYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGR 509
Query: 275 MQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ------QPPVAQNQPSQLPPQSQTQPLV 328
P P+ A + + + Q + P + + +PP+ Q P P SQT P+
Sbjct: 510 GMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQ 569
Query: 329 SQAQALPG---QMLYTQPPLKFVRAPM----VVQQPPVQ-----PQVQQQQTAVQTAQAA 376
+ G ++ + PLK AP+ +Q P + P A+ A A
Sbjct: 570 RPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQPTRNLAAFPASHDPDPAI-PAPTA 628
Query: 377 QMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQ-PGQPSSQPNSNVSSGPAP 435
A G + Q+S P +S PG P + P + P+ P + SS + +SG
Sbjct: 629 TPSARGAVIRQNSDP--TSEGPGPSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSGAGG 686
Query: 436 SPSSFLPSPSPQPS-------QSPVTARTPQNFSVPS--PGPLNTPVNPSSVMSPAGSSQ 486
S + P+ + Q TP+ P+ PGP N NP S G +
Sbjct: 687 SRPAQAVRARPRSNSAWQIYLQRRAERGTPKPPGPPAQPPGPPNASSNPDLRRSDPGWER 746
Query: 487 AE 488
++
Sbjct: 747 SD 748
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 92.8 bits (229), Expect = 1e-18
Identities = 96/411 (23%), Positives = 164/411 (39%), Gaps = 68/411 (16%)
Query: 115 SLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQ--------- 165
S G G+P S+ P G S + + + ++ QQ LQQQQQ
Sbjct: 332 SHGEEGEPSSIMNVP--GESTLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKH 389
Query: 166 ---------QQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQ 216
++Q +++++ QQ+++++Q++ + +Q + QA+ +++++ Q +++Q
Sbjct: 390 LLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQ 449
Query: 217 QQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL--QAQPPIQQPP 274
+ +L Q Q + Q+Q Q + LQQQQQQQQ Q+QQQQQ L +P
Sbjct: 450 EYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGR 509
Query: 275 MQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ------QPPVAQNQPSQLPPQSQTQPLV 328
P P+ A + + + Q + P + + +PP+ Q P P SQT P+
Sbjct: 510 GMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQ 569
Query: 329 SQAQALPG---QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQV 385
+ G ++ + PLK AP+ P +Q Q T
Sbjct: 570 RPVEPQEGPHKSLVAHRVPLKPYAAPV-----PRSQSLQDQPTR---------------- 608
Query: 386 SQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPS------- 438
+ ++ P P P ++P P G Q + S GP PSP+
Sbjct: 609 NLAAFPASHDPDP--------AIPAPTATPSARGAVIRQNSDPTSEGPGPSPNPPAWVRP 660
Query: 439 -SFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAE 488
+ P PQ + S TA P NP S G +++
Sbjct: 661 DNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRASNPDLRRSDPGWERSD 711
>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
Length = 1295
Score = 92.8 bits (229), Expect = 1e-18
Identities = 96/411 (23%), Positives = 164/411 (39%), Gaps = 68/411 (16%)
Query: 115 SLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQ--------- 165
S G G+P S+ P G S + + + ++ QQ LQQQQQ
Sbjct: 332 SHGEEGEPSSIMNVP--GESTLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKH 389
Query: 166 ---------QQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQ 216
++Q +++++ QQ+++++Q++ + +Q + QA+ +++++ Q +++Q
Sbjct: 390 LLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQ 449
Query: 217 QQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL--QAQPPIQQPP 274
+ +L Q Q + Q+Q Q + LQQQQQQQQ Q+QQQQQ L +P
Sbjct: 450 EYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGR 509
Query: 275 MQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ------QPPVAQNQPSQLPPQSQTQPLV 328
P P+ A + + + Q + P + + +PP+ Q P P SQT P+
Sbjct: 510 GMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQ 569
Query: 329 SQAQALPG---QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQV 385
+ G ++ + PLK AP+ P +Q Q T
Sbjct: 570 RPVEPQEGPHKSLVAHRVPLKPYAAPV-----PRSQSLQDQPTR---------------- 608
Query: 386 SQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPS------- 438
+ ++ P P P ++P P G Q + S GP PSP+
Sbjct: 609 NLAAFPASHDPDP--------AIPAPTATPSARGAVIRQNSDPTSEGPGPSPNPPAWVRP 660
Query: 439 -SFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAE 488
+ P PQ + S TA P NP S G +++
Sbjct: 661 DNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRASNPDLRRSDPGWERSD 711
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 92.4 bits (228), Expect = 1e-18
Identities = 130/498 (26%), Positives = 177/498 (35%), Gaps = 82/498 (16%)
Query: 71 NKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPP 130
NK+ + V+ AL + G A PPR G L +M +
Sbjct: 2614 NKRLASPVAP--GALTTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTS 2671
Query: 131 PGTSGMAPHSMAVVSTAT----PQ----TQLQLQQVALQQQQQQQQFQQQQQAALQQQQQ 182
S + ++ V T PQ T +QL + Q QQQQQ QQQQQ
Sbjct: 2672 VTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQ 2731
Query: 183 QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIA 242
QQQQQQ Q QQ QQ Q Q+Q Q Q + + + + + Q+Q
Sbjct: 2732 QQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQ----- 2786
Query: 243 QLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQ-PQ------PPPSQAL--------- 286
+LQ+ Q Q Q Q Q Q QPP QQ PQ P P L
Sbjct: 2787 KLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQ 2846
Query: 287 --------PQQLQQMHHTQHHQPPPQP---QQPPVAQNQPSQL-PPQSQTQPL------- 327
QLQ Q P P +PPV + + P T P+
Sbjct: 2847 VARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLPMNVAGISV 2906
Query: 328 -VSQAQALPGQMLYTQP----PLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV-AP 381
+ Q Q GQ + QP L ++ V QQ +QPQ Q AVQ AQ + P
Sbjct: 2907 AIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTP 2966
Query: 382 GVQ--VSQSSLPMLSSP------------SPGQQVQTPQSMPPPPQPSPQPGQPSS-QPN 426
G Q V+ ++ P L + + QQVQT + PQ Q +S Q
Sbjct: 2967 GAQQKVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTPVASIQQV 3026
Query: 427 SNVSSGPAPSPSSFLPSPSPQPSQSPVTART-----------PQNFSVPSPGPLNTPVNP 475
++ S +P + + + + A T Q + PL TP P
Sbjct: 3027 ASASQQASPQTVALTQATAAGQQVQMIPAVTATAQVVQQKLIQQQVVTTASAPLQTPGAP 3086
Query: 476 SSVMSPAGSSQAEEQQYL 493
+ PA S +Q L
Sbjct: 3087 NPAQVPASSDSPSQQPKL 3104
Score = 86.7 bits (213), Expect = 7e-17
Identities = 99/343 (28%), Positives = 145/343 (42%), Gaps = 39/343 (11%)
Query: 196 MQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQ 255
+Q +++V Q Q Q + + H Q +Q QQQQQQ Q Q Q QQQQQQQQQ
Sbjct: 2685 VQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQ---QQQQQQQQQQQQQ 2741
Query: 256 QQQQQQQALQAQPPIQQPPMQQPQPPPSQAL----PQQLQQMHHTQHHQPPPQPQQPPVA 311
QQQQQQ +Q + Q Q P +A+ P+ L +M Q Q PPQP PP A
Sbjct: 2742 QQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKM-QKQKLQMPPQP-PPPQA 2799
Query: 312 QNQPSQ----------LPPQSQTQPLVSQAQALPGQML------------YTQPPLKFVR 349
Q+ P Q PPQ Q+ L + PG +L T+ P ++
Sbjct: 2800 QSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQVARLTRVPTSQLQ 2859
Query: 350 APMVVQ-QPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQV---QTP 405
A +Q Q P QV + V + AA + +PGV ++ +S Q QT
Sbjct: 2860 AQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKAAGQTV 2919
Query: 406 QSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPS 465
+ P Q + Q + Q + A P++ + Q +P + + P+
Sbjct: 2920 VAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPA 2979
Query: 466 PGP--LNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPL 506
L TP+ S AG+ Q + Q + KL Q+ + P+
Sbjct: 2980 LKTQFLTTPI--SQAQKLAGAQQVQTQIQVAKLPQVVQQQTPV 3020
Score = 81.3 bits (199), Expect = 3e-15
Identities = 114/457 (24%), Positives = 178/457 (38%), Gaps = 83/457 (18%)
Query: 93 AAGAAGIGM----PPRGPGQSLGGMGSLGAMGQPMSLSGQP--PPGTSGM--APHSMAVV 144
A GAAG GM PP P ++ P LS P G +GM P + +
Sbjct: 305 AGGAAGFGMTSPPPPTSPSRT----------AVPPGLSSLPLTSVGNTGMKKVPKKLEEI 354
Query: 145 STATPQTQLQLQQVALQQQQQQQQ-----FQQQQQAALQQQQQQQQQQQFQAQQSAMQQQ 199
A+P+ Q+++ L Q+ Q F++ Q Q F A +
Sbjct: 355 PPASPE-MAQMRKQCLDYHYQEMQALKEVFKEYLIELFFLQHFQGNMMDFLAFKKKHYAP 413
Query: 200 FQAVVQQQQ-QLQQQQQQQQHLIKLHHQNQQQIQQQQQ---QLQRIAQLQLQQQQQQQQQ 255
QA ++Q +++++++++ + + I +Q L A ++ ++QQ
Sbjct: 414 LQAYLRQNDLDIEEEEEEEEE----EEEKSEVINDEQALAGSLVAGAGSTVETDLFKRQQ 469
Query: 256 QQQQQQQALQAQPPIQQPPMQQ---PQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVA- 311
A Q++ P + Q P +P LQQ+ T PP PQ +A
Sbjct: 470 AMPSTGMAEQSKRPRLEVGHQGVVFQHPGADAGVP--LQQLMPTAQGGMPPTPQAAQLAG 527
Query: 312 ------QNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPP-------LKFVRAPMVVQ--- 355
Q PS PP L + LPG++ P L+F + P VV+
Sbjct: 528 QRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQFAQQPQVVEAQT 587
Query: 356 QPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQ-QVQTPQ-------- 406
Q + + QQ + ++Q+ P Q +Q +L + P+PG+ QVQ Q
Sbjct: 588 QLQIPVKTQQPNVPIPAPPSSQLPIPPSQPAQLALHV---PTPGKVQVQASQLSSLPQMV 644
Query: 407 --------SMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFL--PSPSPQPSQSPVTAR 456
PP P+P P S P S GP+P+ SS + PS + + SPVT+R
Sbjct: 645 ASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPGPSPARSSPVNRPSSATNKALSPVTSR 704
Query: 457 TPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYL 493
TP + + P P S A SSQ Q L
Sbjct: 705 TPGVVA-------SAPTKPQSPAQNATSSQDSSQDTL 734
Score = 65.5 bits (158), Expect = 2e-10
Identities = 79/345 (22%), Positives = 132/345 (38%), Gaps = 39/345 (11%)
Query: 240 RIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHH 299
++A L+ ++ ++++ QQ+ QP + QPP QPQPPP P
Sbjct: 2476 QVASLRAERIAKEKKALADQQKAQ---QPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAGS 2532
Query: 300 QPP-------PQPQQPPVAQNQPSQLPPQSQTQPLVS---QAQALPG----QMLYTQPPL 345
QPP PQPQ P Q QP Q P ++ QP ++ A L G + T P
Sbjct: 2533 QPPAGPPAVQPQPQPQPQTQPQPVQAP--AKAQPAITTGGSAAVLAGTIKTSVTGTSMPT 2590
Query: 346 KFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTP 405
V ++V P Q + A VAPG +L +P Q V T
Sbjct: 2591 GAVSGNVIVNTIAGVPAATFQSI---NKRLASPVAPG------ALTTPGGSAPAQVVHT- 2640
Query: 406 QSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPS 465
PPP+ P + S ++ + +S S + +PV +TP VP
Sbjct: 2641 ---QPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTPV--QTPARSLVPQ 2695
Query: 466 PGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSK 525
P ++PA +QQ + +Q + + ++ + + + +
Sbjct: 2696 VSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQ 2755
Query: 526 MKSLLDILTDPSKRCPLKTLQKC--EIALEKLKNDMAVPTPPPPP 568
+ + P++ +K + K E ++ K + +P PPPP
Sbjct: 2756 VPQIQGQAQSPAQ---IKAVGKLTPEHLIKMQKQKLQMPPQPPPP 2797
Score = 57.4 bits (137), Expect = 5e-08
Identities = 83/282 (29%), Positives = 105/282 (37%), Gaps = 68/282 (24%)
Query: 86 QSLTGGPAAGAAGIGMPP---------RGPGQSLGGMGSLG---AMGQPMSLSGQPPPGT 133
Q T P + PP PG + M G A+GQP +GQ
Sbjct: 2863 QMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKAAGQT---- 2918
Query: 134 SGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQ-------Q 186
V Q L+L+Q A+QQQ+ Q Q AA+QQ+ QQ Q
Sbjct: 2919 --------VVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQ 2970
Query: 187 QQFQAQQSAMQQQFQAV-VQQQQQLQ--QQQQQQQHLIKLHHQNQQQ-----IQQ----- 233
+ A Q A++ QF + Q Q+L QQ Q Q + KL QQQ IQQ
Sbjct: 2971 KVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTPVASIQQVASAS 3030
Query: 234 QQQQLQRIAQLQLQQQQQQQQ-------------QQQQQQQQALQAQPPIQQPPMQQP-Q 279
QQ Q +A Q QQ Q Q+ QQQ A P+Q P P Q
Sbjct: 3031 QQASPQTVALTQATAAGQQVQMIPAVTATAQVVQQKLIQQQVVTTASAPLQTPGAPNPAQ 3090
Query: 280 PPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQ 321
P S P Q QP Q + P V P++ P Q
Sbjct: 3091 VPASSDSPSQ----------QPKLQMRVPAVRLKTPTKPPCQ 3122
Score = 55.5 bits (132), Expect = 2e-07
Identities = 99/370 (26%), Positives = 136/370 (36%), Gaps = 56/370 (15%)
Query: 259 QQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHH---QPPPQPQQPPVAQNQP 315
Q QA + P Q P S A P +L+ Q QPPPQPQ P A Q
Sbjct: 1488 QTSQASASAPRHQ--PASASSTAASPAHPAKLRAQTTAQASTPGQPPPQPQAPSHAAGQ- 1544
Query: 316 SQLPPQSQTQPLVSQAQA-LPGQMLYTQPPLKFVRAPMV-VQQP--PVQPQVQQQQTAVQ 371
S LP Q L SQAQA LP + L + P V QP PV Q Q + +
Sbjct: 1545 SALP---QRLVLPSQAQARLPSGEVVKIAQLASITGPQSRVAQPETPVTLQFQGSKFTLS 1601
Query: 372 TAQAAQMVA-PGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVS 430
+Q Q+ A +Q+ S L ++S+P P P P Q SQ + V
Sbjct: 1602 HSQLRQLTAGQPLQLQGSVLQIVSAP----------GQPYLRAPGPVVMQTVSQAGA-VH 1650
Query: 431 SGPAPSPSSFLPSPSPQPSQSPVTARTPQN-FSVPSPGPLNTPVNPSSVMSPAGSSQAEE 489
P + PSP+P Q V R N +V PG + P SP G EE
Sbjct: 1651 GALGSKPPAGGPSPAPLTPQVGVPGRVAVNALAVGEPGTASKPA------SPIGGPTQEE 1704
Query: 490 QQYLDKLKQLSKYIEPLRRMINKIDKNED----------------------RKKDLSKMK 527
+ L K + Y+ RR D R K+
Sbjct: 1705 KTRLLKERLDQIYLVNERRCSQAPVYGRDLLRICALPSHGRVQWRGSLDGRRGKEAGPAH 1764
Query: 528 SLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLA 587
S PS+ + TL +C +L+ + + +A PP PP+ + PL +
Sbjct: 1765 SYTSSSESPSEL--MLTLCRCGESLQDVIDRVAFVIPPVVAAPPSLRVPRPPPLYSHRMR 1822
Query: 588 NIRSPVFNHS 597
+R + H+
Sbjct: 1823 ILRQGLREHA 1832
Score = 48.9 bits (115), Expect = 2e-05
Identities = 67/261 (25%), Positives = 95/261 (36%), Gaps = 33/261 (12%)
Query: 131 PGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQ 190
PG + + P ++A +S A Q Q Q + Q QQ + +Q A+QQQ+ Q Q
Sbjct: 2892 PGVTTL-PMNVAGISVAIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQA--- 2947
Query: 191 AQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQ 250
AQ A QQ + QQ QQ+ Q + Q Q++A Q Q
Sbjct: 2948 AQGPAAVQQ---KITAQQITTPGAQQKVAYAAQPALKTQFLTTPISQAQKLAGAQ----Q 3000
Query: 251 QQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPV 310
Q Q Q + Q +Q Q P+ +QQ QA PQ V
Sbjct: 3001 VQTQIQVAKLPQVVQQQTPVAS--IQQVASASQQASPQT--------------------V 3038
Query: 311 AQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAV 370
A Q + Q Q P V+ + Q L Q + AP+ P QV +
Sbjct: 3039 ALTQATAAGQQVQMIPAVTATAQVVQQKLIQQQVVTTASAPLQTPGAPNPAQVPASSDSP 3098
Query: 371 QTAQAAQMVAPGVQVSQSSLP 391
QM P V++ + P
Sbjct: 3099 SQQPKLQMRVPAVRLKTPTKP 3119
Score = 40.0 bits (92), Expect = 0.008
Identities = 56/183 (30%), Positives = 67/183 (36%), Gaps = 32/183 (17%)
Query: 273 PPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQ 332
P Q Q S+A P + H PPP P P PS PQS + +
Sbjct: 7 PQNVQHQLQRSRACPGS-EGEEQPAHPNPPPSPAAPFAPSASPSA--PQSPSYQI----- 58
Query: 333 ALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQ-QQQTAVQTAQAAQMVAPGVQVS----- 386
Q L + P + +Q V P V QQ + +PG Q S
Sbjct: 59 ----QQLMNRSPATGQNVNITLQS--VGPVVGGNQQITLAPLPLPSPTSPGFQFSAQPRR 112
Query: 387 --QSSLPMLSSPSP-GQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPS 443
S + SP QQVQT P QPSP PGQ NV +G AP P L S
Sbjct: 113 FEHGSPSYIQVTSPLSQQVQTQS----PTQPSPGPGQAL----QNVRAG-APGPGLGLCS 163
Query: 444 PSP 446
SP
Sbjct: 164 SSP 166
Score = 40.0 bits (92), Expect = 0.008
Identities = 43/164 (26%), Positives = 57/164 (34%), Gaps = 17/164 (10%)
Query: 252 QQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVA 311
Q Q Q Q+ +A +QP P PPPS A P P PQ P
Sbjct: 8 QNVQHQLQRSRACPGSEGEEQPA--HPNPPPSPAAP--------FAPSASPSAPQSPSYQ 57
Query: 312 QNQPSQLPP---QSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQT 368
Q P Q+ L S + G T PL P Q Q ++
Sbjct: 58 IQQLMNRSPATGQNVNITLQSVGPVVGGNQQITLAPLPLPSP----TSPGFQFSAQPRRF 113
Query: 369 AVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPP 412
+ Q+ +P Q Q+ P SP PGQ +Q ++ P P
Sbjct: 114 EHGSPSYIQVTSPLSQQVQTQSPTQPSPGPGQALQNVRAGAPGP 157
Score = 37.7 bits (86), Expect = 0.039
Identities = 39/176 (22%), Positives = 56/176 (31%), Gaps = 33/176 (18%)
Query: 323 QTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPG 382
+T + +Q + LYT ++ + PP++P + A+ + G
Sbjct: 2407 RTSQIYAQDENATHTQLYTSH-FDLMKMTAGKRSPPIKPLLGMNPFQKNPKHASVLAESG 2465
Query: 383 VQVSQSSLPM----------------LSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPN 426
+ + P+ L+ QQ Q PP PQP P P QP
Sbjct: 2466 INYDKPLPPIQVASLRAERIAKEKKALADQQKAQQPAVAQPPPPQPQPPPPPQQP----- 2520
Query: 427 SNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPA 482
P P LP P SQ P Q P P PV + PA
Sbjct: 2521 --------PPP---LPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPA 2565
Score = 35.8 bits (81), Expect = 0.15
Identities = 41/154 (26%), Positives = 60/154 (38%), Gaps = 21/154 (13%)
Query: 315 PSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQ 374
PS PP++ + A A P L +PP+ A P+ + QT+Q
Sbjct: 1444 PSTHPPRTAAP---TTASAAPQGPLRGRPPIATFSA---------NPEAKAAAAPFQTSQ 1491
Query: 375 AAQMVAPGVQVSQSSLPMLSSPSPGQ-QVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGP 433
A+ AP Q + +S S P + + QT P QP PQP PS ++G
Sbjct: 1492 ASAS-APRHQPASASSTAASPAHPAKLRAQTTAQASTPGQPPPQPQAPSH------AAGQ 1544
Query: 434 APSPSSF-LPSPSPQPSQSPVTARTPQNFSVPSP 466
+ P LPS + S + Q S+ P
Sbjct: 1545 SALPQRLVLPSQAQARLPSGEVVKIAQLASITGP 1578
Score = 33.5 bits (75), Expect = 0.74
Identities = 72/294 (24%), Positives = 96/294 (32%), Gaps = 75/294 (25%)
Query: 245 QLQQQQQQQQQQQQQQQQALQAQPPI---QQPPMQQPQPPPSQALP--QQLQQMHHTQHH 299
Q+QQ + Q LQ+ P+ Q P P PS P Q Q +H
Sbjct: 57 QIQQLMNRSPATGQNVNITLQSVGPVVGGNQQITLAPLPLPSPTSPGFQFSAQPRRFEHG 116
Query: 300 QPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQAL---------PGQMLYTQPPLK-FVR 349
P P++Q Q+ QS TQP QAL PG L + P FV
Sbjct: 117 SPSYIQVTSPLSQ----QVQTQSPTQPSPGPGQALQNVRAGAPGPGLGLCSSSPTGGFVD 172
Query: 350 APMVVQQPPVQPQ------VQQQQTAVQTAQAAQMVA--PGVQVSQ-------------- 387
A ++V+Q + P Q Q AQ AQ+ PG ++
Sbjct: 173 ASVLVRQISLSPSSGGHFVFQDGSGLTQIAQGAQVQLQHPGTPITVRERRPSQPHTQSGG 232
Query: 388 ---------------SSLPMLSSPS---------------PGQQVQTPQSMPPPPQPSPQ 417
+ L L+SPS GQ VQ Q + PP P P
Sbjct: 233 TIHHLGPQSPAAAGGAGLQPLASPSHITTANLPPQISSIIQGQLVQQQQVLQGPPLPRPL 292
Query: 418 PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNT 471
+ V A + F + P P+ TA P S+P NT
Sbjct: 293 ----GFERTPGVLLPGAGGAAGFGMTSPPPPTSPSRTAVPPGLSSLPLTSVGNT 342
>gi|15812226 transcriptional regulating factor 1 [Homo sapiens]
Length = 1200
Score = 87.4 bits (215), Expect = 4e-17
Identities = 129/467 (27%), Positives = 167/467 (35%), Gaps = 93/467 (19%)
Query: 139 HSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQ 198
H+ + V P + L+ Q Q+ + A+ + QQ QQ + +
Sbjct: 167 HTQSAVMDGAPDSALR--------QLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSK 218
Query: 199 QFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQ----QQQQQQ 254
V Q Q QQ L ++ Q Q +Q Q Q + Q+Q Q QQQQQ
Sbjct: 219 PALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQA 278
Query: 255 QQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQ------QMHHTQHHQPPPQPQ-- 306
QQ+ Q +Q QP QQ QPQPPP Q PQQLQ M Q++QP P Q
Sbjct: 279 GQQRISMQEIQTQP--QQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHL 336
Query: 307 ----------QPPVAQNQPSQLPPQS----QTQPLVSQAQALPGQMLYTQPPLKFVRAPM 352
QPP P Q P+ Q PL S +Q Y Q P
Sbjct: 337 QEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQ------YYYQEP-------- 382
Query: 353 VVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPP 412
QQP P QQ ++ Q S L SS Q + + PP
Sbjct: 383 --QQPYSHPLYQQSH-----------LSQHQQREDSQLKTYSSDRQAQAMLSSHGDLGPP 429
Query: 413 QPSPQPGQPSSQPNSNVSS----GPAPSPSSF-LPSPSPQPSQSPVTARTPQNFSVPSPG 467
G P+S + VSS P SPS L + PQ Q +A PQ + P
Sbjct: 430 DTG--MGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQ---MHLPD 484
Query: 468 PLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMK 527
P +P S P G A +Q+ K K L+ N N M+
Sbjct: 485 GRAQPGSPESSGQPKG---AFGEQFDAKNKLTCSIC--LKEFKNLPALN-------GHMR 532
Query: 528 SLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQ 574
S + P+ K E + L P PPPPP PP Q
Sbjct: 533 SHGGMRASPN--------LKQEEGEKVLPPQPQPPLPPPPPPPPPPQ 571
Score = 75.9 bits (185), Expect = 1e-13
Identities = 129/541 (23%), Positives = 188/541 (34%), Gaps = 112/541 (20%)
Query: 114 GSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQ 173
G G + +P GQ P T G H Q +Q Q Q Q QQ Q
Sbjct: 211 GFTGGLSKPALQVGQHP--TQG---HLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQ 265
Query: 174 QAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQ 233
Q QQQQQ Q + +Q Q Q + Q Q QQQQ Q L Q QI Q
Sbjct: 266 QHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQ 325
Query: 234 QQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQP----PIQQPPM--------QQPQPP 281
Q + LQ QQQQQ Q + Q P +Q P+ Q+PQ P
Sbjct: 326 YYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQP 385
Query: 282 PSQALPQQLQQMHHTQHHQ-------------------------PPPQPQQPPVAQNQPS 316
S L QQ H +QH Q PP A + +
Sbjct: 386 YSHPL---YQQSHLSQHQQREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLT 442
Query: 317 QLPPQSQTQPLVS-----------QAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQ--- 362
++ +PL+S Q Q L ++ Q L RA + QP+
Sbjct: 443 RVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAF 502
Query: 363 -----VQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPS----PGQQVQTPQSMPPPPQ 413
+ + T + + + +S M +SP+ G++V PQ PP P
Sbjct: 503 GEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPP 562
Query: 414 PSPQPGQPSSQPNSNVSSG---PAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLN 470
P P P P P + + P P LP P+PS T +
Sbjct: 563 PPPPPPPPQLPPEAESLTPMVMPVSVPVKLLP---PKPSSQGFTN--------------S 605
Query: 471 TPVNPSSVMSPAGSSQAEEQQYLDKLKQ----LSKYIEPLRRMINKIDKNEDRKKDLSKM 526
T PS+ PA S +E L+ ++ + K EPL+ + +++KK +
Sbjct: 606 TVAAPSARDKPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTV-------QEKKKFRHRP 658
Query: 527 KSLL-----DILTDPSKRCPLKTLQKCEIALEKLKNDMAV--------PTPPPPPVPPTK 573
+ L +P+ TL + ++ ++ D + P PPP + P +
Sbjct: 659 EPLFIPPPPSYNPNPAASYSGATLYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVR 718
Query: 574 Q 574
Q
Sbjct: 719 Q 719
Score = 50.1 bits (118), Expect = 8e-06
Identities = 49/235 (20%), Positives = 85/235 (36%), Gaps = 43/235 (18%)
Query: 259 QQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQL 318
+Q++ + PP QPP+ P PPP PPP QL
Sbjct: 544 KQEEGEKVLPPQPQPPLPPPPPPP------------------PPP-------------QL 572
Query: 319 PPQSQTQPLVSQAQALPGQMLYTQPPLK-FVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQ 377
PP++++ + ++P ++L +P + F + + +P + + +
Sbjct: 573 PPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDEMPVLEIPR 632
Query: 378 MVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAP-- 435
P V ++ L + + P +PPPP +P P S S +P
Sbjct: 633 KHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQSQLRSPRV 692
Query: 436 -------SPSSFLPSPSPQPSQSPVTARTP--QNFSVPSPGPLNTPVNPSSVMSP 481
P+ LP +P P SPV + N + GP P P + ++P
Sbjct: 693 LGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLTPLTP 747
Score = 46.6 bits (109), Expect = 8e-05
Identities = 55/215 (25%), Positives = 76/215 (35%), Gaps = 28/215 (13%)
Query: 239 QRIAQLQLQQQQQQQQQQQQQQQQALQAQPP--IQQPPMQQPQPPPSQALPQQLQQMHHT 296
Q A L+ Q Q Q + P ++Q Q+P PP+ A+P + QQ+
Sbjct: 148 QVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQQ 207
Query: 297 QHHQPPPQPQQPPVAQNQ-PSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQ 355
H +P + Q P+Q Q ++Q GQ L +AP ++
Sbjct: 208 PHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPL---------QAPQMLS 258
Query: 356 QPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPS 415
Q Q Q Q Q QA Q ++S + Q Q Q P PQP
Sbjct: 259 QHMQQMQQHQYYPPQQQQQAGQQ-----RISMQEI----------QTQPQQIRPSQPQPP 303
Query: 416 PQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQ 450
PQ QP Q G P + P P Q Q
Sbjct: 304 PQQQQP-QQLQLQQRQGSMQIPQYYQPQPMMQHLQ 337
>gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens]
Length = 1420
Score = 85.5 bits (210), Expect = 2e-16
Identities = 87/260 (33%), Positives = 112/260 (43%), Gaps = 38/260 (14%)
Query: 94 AGAAGIGMPPRGP----GQSLGGMG-SLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTAT 148
AG G P +GP G L G S +M M+ G P GM P + +
Sbjct: 1108 AGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFP--LQGMHPRANIMRPRTN 1165
Query: 149 PQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQ-----FQAV 203
QL++Q LQQ+ Q QQF Q + AL+ + + + MQ Q Q V
Sbjct: 1166 TPKQLRMQ---LQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQGFLNAQMV 1222
Query: 204 VQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQA 263
Q+ ++L +QQ + + Q QQQ QQQQQQ QQQQQQQQQQQQQQQ
Sbjct: 1223 AQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQ----------QQQQQQQQQQQQQQQQ 1272
Query: 264 LQAQPP----IQQPPMQ--QPQPPPSQALPQQL-QQMHHTQHHQPPP---QPQQPPVAQN 313
QA P P M P QA PQQ Q ++ QP P + PP A
Sbjct: 1273 TQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQPDPAFGRVSSPPNAMM 1332
Query: 314 QPSQLPPQSQTQPLVSQAQA 333
P Q+ P++ QA
Sbjct: 1333 SSRMGPSQN---PMMQHPQA 1349
Score = 59.7 bits (143), Expect = 1e-08
Identities = 85/345 (24%), Positives = 128/345 (37%), Gaps = 54/345 (15%)
Query: 119 MGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQL-------QLQQVALQQQQQQQQFQQ 171
+G P +L GQ H++ + AT ++ +L + +Q FQ
Sbjct: 1038 VGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPELVNQGQALEPKQDAFQG 1097
Query: 172 QQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQ--QLQQQQQQQQHLIKLHHQNQQ 229
Q+ A + Q+ Q + AQ MQ F Q + Q QQ + +
Sbjct: 1098 QEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRA 1157
Query: 230 QIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQ 289
I + + + ++QLQQ+ Q QQ Q +Q AL+ + M+ P + +
Sbjct: 1158 NIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQ-ALELK-------MENPTAGGAAVM--- 1206
Query: 290 LQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVR 349
+P QPQQ + +Q + + Q A+ Q Q
Sbjct: 1207 ----------RPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQ------- 1249
Query: 350 APMVVQQPPVQPQVQQQQTAVQTAQAAQMVA----PGVQVSQSSLPMLSSPSPGQQVQTP 405
QQ Q Q QQQQ Q Q Q A P V S S +L+ P+ Q P
Sbjct: 1250 -----QQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQ--APP 1302
Query: 406 QSMPPPP------QPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSP 444
Q P P QP P G+ SS PN+ +SS PS + + P
Sbjct: 1303 QQFPYQPNYGMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHP 1347
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.125 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,136,429
Number of Sequences: 37866
Number of extensions: 2548854
Number of successful extensions: 102590
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1370
Number of HSP's successfully gapped in prelim test: 2285
Number of HSP's that attempted gapping in prelim test: 20451
Number of HSP's gapped (non-prelim): 30738
length of query: 748
length of database: 18,247,518
effective HSP length: 110
effective length of query: 638
effective length of database: 14,082,258
effective search space: 8984480604
effective search space used: 8984480604
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.