BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|212720889 bestrophin 1 isoform 2 [Homo sapiens] (604 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|212720889 bestrophin 1 isoform 2 [Homo sapiens] 1259 0.0 gi|4759310 bestrophin 1 isoform 1 [Homo sapiens] 1079 0.0 gi|115527104 vitelliform macular dystrophy 2-like 3 isoform 1 [H... 446 e-125 gi|119703742 vitelliform macular dystrophy 2-like 1 [Homo sapiens] 432 e-121 gi|23397576 bestrophin 4 [Homo sapiens] 390 e-108 gi|115527106 vitelliform macular dystrophy 2-like 3 isoform 2 [H... 184 2e-46 gi|224451082 cytospin A [Homo sapiens] 36 0.089 gi|224451080 cytospin A [Homo sapiens] 36 0.089 gi|50345877 arginyltransferase 1 isoform 1 [Homo sapiens] 36 0.089 gi|119220605 ubiquitin specific protease 10 [Homo sapiens] 35 0.15 gi|61675704 hypothetical protein LOC347487 [Homo sapiens] 34 0.34 gi|157785645 SPEG complex locus [Homo sapiens] 34 0.34 gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ... 32 2.2 gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ... 32 2.2 gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ... 32 2.2 gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ... 32 2.2 gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 ... 32 2.2 gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] 31 3.8 gi|27886651 potassium voltage-gated channel, subfamily H, member... 30 4.9 gi|83367077 mucin 16 [Homo sapiens] 30 6.4 gi|150170670 piccolo isoform 2 [Homo sapiens] 30 8.4 gi|150378539 piccolo isoform 1 [Homo sapiens] 30 8.4 gi|24307933 transcription factor EB [Homo sapiens] 30 8.4 >gi|212720889 bestrophin 1 isoform 2 [Homo sapiens] Length = 604 Score = 1259 bits (3259), Expect = 0.0 Identities = 604/604 (100%), Positives = 604/604 (100%) Query: 1 MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ 60 MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ Sbjct: 1 MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ 60 Query: 61 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM 120 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM Sbjct: 61 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM 120 Query: 121 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV 180 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV Sbjct: 121 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV 180 Query: 181 TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGE 240 TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGE Sbjct: 181 TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGE 240 Query: 241 DDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFM 300 DDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFM Sbjct: 241 DDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFM 300 Query: 301 GSTFNISLNKEEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESL 360 GSTFNISLNKEEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESL Sbjct: 301 GSTFNISLNKEEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESL 360 Query: 361 LHEGLPKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFP 420 LHEGLPKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFP Sbjct: 361 LHEGLPKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFP 420 Query: 421 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN 480 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN Sbjct: 421 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN 480 Query: 481 LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENRSVLHLNQGHCIALCPTPASL 540 LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENRSVLHLNQGHCIALCPTPASL Sbjct: 481 LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENRSVLHLNQGHCIALCPTPASL 540 Query: 541 ALSLPFLHNFLGFHHCQSTLDLRPALAWGIYLATFTGILGKCSGPFLTSPWYHPEDFLGP 600 ALSLPFLHNFLGFHHCQSTLDLRPALAWGIYLATFTGILGKCSGPFLTSPWYHPEDFLGP Sbjct: 541 ALSLPFLHNFLGFHHCQSTLDLRPALAWGIYLATFTGILGKCSGPFLTSPWYHPEDFLGP 600 Query: 601 GEGR 604 GEGR Sbjct: 601 GEGR 604 >gi|4759310 bestrophin 1 isoform 1 [Homo sapiens] Length = 585 Score = 1079 bits (2790), Expect = 0.0 Identities = 521/524 (99%), Positives = 521/524 (99%) Query: 1 MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ 60 MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ Sbjct: 61 MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ 120 Query: 61 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM 120 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM Sbjct: 121 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM 180 Query: 121 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV 180 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV Sbjct: 181 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV 240 Query: 181 TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGE 240 TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGE Sbjct: 241 TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGE 300 Query: 241 DDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFM 300 DDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFM Sbjct: 301 DDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFM 360 Query: 301 GSTFNISLNKEEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESL 360 GSTFNISLNKEEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESL Sbjct: 361 GSTFNISLNKEEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESL 420 Query: 361 LHEGLPKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFP 420 LHEGLPKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFP Sbjct: 421 LHEGLPKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFP 480 Query: 421 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN 480 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN Sbjct: 481 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN 540 Query: 481 LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENRSVLH 524 LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENR H Sbjct: 541 LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENRDEAH 584 >gi|115527104 vitelliform macular dystrophy 2-like 3 isoform 1 [Homo sapiens] Length = 668 Score = 446 bits (1146), Expect = e-125 Identities = 213/353 (60%), Positives = 259/353 (73%), Gaps = 5/353 (1%) Query: 2 FEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQG 61 FEKL++YCD Y + IP++FVLGFYVTLVV RWWNQ+ NLPWPDRLM L+S V G DE G Sbjct: 62 FEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISSSVHGSDEHG 121 Query: 62 RLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNMF 121 RLLRRTL+RY NL ++LI RSVSTAVYKRFP+ H+V+AGFMT E K L PH + Sbjct: 122 RLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTTDERKLFNHLKSPHLKY 181 Query: 122 WVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVVT 181 WVP++WF NL+ KA GRIRD + LQSL+ EMN R+ C L+ YDW+ IPLVYTQVVT Sbjct: 182 WVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFGYDWVGIPLVYTQVVT 241 Query: 182 VAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGED 241 +AVY+FF CL+GRQFL+P K Y GH+LDL +P+FT LQFFFY GWLKVAEQLINPFGED Sbjct: 242 LAVYTFFFACLIGRQFLDPTKGYAGHDLDLYIPIFTLLQFFFYAGWLKVAEQLINPFGED 301 Query: 242 DDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFMG 301 DDDFETNW +DRNLQVSLLAVDEMH LP+M+ D+YW+ +PPYT A+A + SF+G Sbjct: 302 DDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARPPYTLAAADYCIPSFLG 361 Query: 302 STFNISLNKEEM---EFQPNQEDEEDAHAGI--IGRFLGLQSHDHHPPRANSR 349 ST + L+ + E+ + E H+ I + RFL H P R + R Sbjct: 362 STVQMGLSGSDFPDEEWLWDYEKHGHRHSMIRRVKRFLSAHEHPSSPRRRSYR 414 >gi|119703742 vitelliform macular dystrophy 2-like 1 [Homo sapiens] Length = 509 Score = 432 bits (1111), Expect = e-121 Identities = 204/316 (64%), Positives = 253/316 (80%), Gaps = 1/316 (0%) Query: 2 FEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQG 61 FEKL +YCD Y LIP+SFVLGFYVTLVV RWW+QY +P PD LM +V+G V G+D++G Sbjct: 62 FEKLVIYCDQYASLIPVSFVLGFYVTLVVNRWWSQYLCMPLPDALMCVVAGTVHGRDDRG 121 Query: 62 RLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNMF 121 RL RRTL+RYA L VLILRSVSTAV+KRFP+ H+V+AGFMT E K+ E L+ +N + Sbjct: 122 RLYRRTLMRYAGLSAVLILRSVSTAVFKRFPTIDHVVEAGFMTREERKKFENLNSSYNKY 181 Query: 122 WVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVVT 181 WVP VWF+NL+ +A GRIRD L+ LL E+N R +CG L+ YDWIS+PLVYTQVVT Sbjct: 182 WVPCVWFSNLAAQARREGRIRDNSALKLLLEELNVFRGKCGMLFHYDWISVPLVYTQVVT 241 Query: 182 VAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGED 241 +A+YS+FL CL+GRQFL+PA+ Y H+LDL VP+FT LQFFFY GWLKVAEQLINPFGED Sbjct: 242 IALYSYFLACLIGRQFLDPAQGYKDHDLDLCVPIFTLLQFFFYAGWLKVAEQLINPFGED 301 Query: 242 DDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASA-QFRRASFM 300 DDDFETN+++DRN QVS+LAVDEM+ DL +E D+YW+ E + PYTAA+ Q R+ SF Sbjct: 302 DDDFETNFLIDRNFQVSMLAVDEMYDDLAVLEKDLYWDAAEARAPYTAATVFQLRQPSFQ 361 Query: 301 GSTFNISLNKEEMEFQ 316 GSTF+I+L KE+M+FQ Sbjct: 362 GSTFDITLAKEDMQFQ 377 >gi|23397576 bestrophin 4 [Homo sapiens] Length = 473 Score = 390 bits (1001), Expect = e-108 Identities = 199/358 (55%), Positives = 251/358 (70%), Gaps = 22/358 (6%) Query: 1 MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ 60 ++ ++ YC+ LIP+SFVLGFYVTLVV RWW+QY ++P PD+LM ++S V G D++ Sbjct: 61 VYAQVARYCNRSADLIPLSFVLGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQR 120 Query: 61 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM 120 GRLLRRTLIRYANL +VL+LRSVST V KRFP+ +H+V AGFM+ E K+ E L N Sbjct: 121 GRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESLKSDFNK 180 Query: 121 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV 180 +WVP VWF NL+ +A GRIRD I L LL E+N R +C L+ YDWISIPLVYTQVV Sbjct: 181 YWVPCVWFTNLAAQARRDGRIRDDIALCLLLEELNKYRAKCSMLFHYDWISIPLVYTQVV 240 Query: 181 TVAVYSFFLTCLVGRQFLNPAKA--------YPGHE-------LDLVVPVFTFLQFFFYV 225 T+AVYSFF LVGRQF+ P PG E D+ VP+ T LQFFFY Sbjct: 241 TIAVYSFFALSLVGRQFVEPEAGAAKPQKLLKPGQEPAPALGDPDMYVPLTTLLQFFFYA 300 Query: 226 GWLKVAEQLINPFGEDDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQP 285 GWLKVAEQ+INPFGEDDDDFETN ++DRNLQVSLL+VDEM+Q+LP E D YW++ +PQP Sbjct: 301 GWLKVAEQIINPFGEDDDDFETNQLIDRNLQVSLLSVDEMYQNLPPAEKDQYWDEDQPQP 360 Query: 286 PYT-AASAQFRRASFMGSTFNISLNKE-----EMEFQPNQ-EDEEDAHAGIIGRFLGL 336 PYT A +A+ R SF+GSTFN+ ++ + ++E P A ++GRFLG+ Sbjct: 361 PYTVATAAESLRPSFLGSTFNLRMSDDPEQSLQVEASPGSGRPAPAAQTPLLGRFLGV 418 >gi|115527106 vitelliform macular dystrophy 2-like 3 isoform 2 [Homo sapiens] Length = 455 Score = 184 bits (467), Expect = 2e-46 Identities = 105/252 (41%), Positives = 131/252 (51%), Gaps = 56/252 (22%) Query: 103 MTPAEHKQLEKLSLPHNMFWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCG 162 MT E K L PH +WVP++WF NL+ KA GRIRD + LQSL+ EMN R+ C Sbjct: 1 MTTDERKLFNHLKSPHLKYWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCS 60 Query: 163 HLYAYDWISIPLVYTQVVTVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFF 222 L+ YDW+ IPLVYTQ Sbjct: 61 LLFGYDWVGIPLVYTQ-------------------------------------------- 76 Query: 223 FYVGWLKVAEQLINPFGEDDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPE 282 VAEQLINPFGEDDDDFETNW +DRNLQVSLLAVDEMH LP+M+ D+YW+ Sbjct: 77 -------VAEQLINPFGEDDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSA 129 Query: 283 PQPPYTAASAQFRRASFMGSTFNISLNKEEM---EFQPNQEDEEDAHAGI--IGRFLGLQ 337 +PPYT A+A + SF+GST + L+ + E+ + E H+ I + RFL Sbjct: 130 ARPPYTLAAADYCIPSFLGSTVQMGLSGSDFPDEEWLWDYEKHGHRHSMIRRVKRFLSAH 189 Query: 338 SHDHHPPRANSR 349 H P R + R Sbjct: 190 EHPSSPRRRSYR 201 >gi|224451082 cytospin A [Homo sapiens] Length = 1117 Score = 36.2 bits (82), Expect = 0.089 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 1/58 (1%) Query: 390 VDAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPS-APSKLHSVTGIDTKDKSLKTVS 446 + +F SA P + P+TPLSP+PM P + +P + HS++G + K L +S Sbjct: 845 IKSFDSASQVPNPAAAAIPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTALS 902 >gi|224451080 cytospin A [Homo sapiens] Length = 1117 Score = 36.2 bits (82), Expect = 0.089 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 1/58 (1%) Query: 390 VDAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPS-APSKLHSVTGIDTKDKSLKTVS 446 + +F SA P + P+TPLSP+PM P + +P + HS++G + K L +S Sbjct: 845 IKSFDSASQVPNPAAAAIPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTALS 902 >gi|50345877 arginyltransferase 1 isoform 1 [Homo sapiens] Length = 518 Score = 36.2 bits (82), Expect = 0.089 Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 7/103 (6%) Query: 331 GRFLGLQSHDHHPPRANSRTKLLWPKR-ESLLHEGLPKN--HKAAKQNVRGQEDNKAWKL 387 G G Q+ H P + K PK E L+ E LP+N HK + VR + +K Sbjct: 227 GELEGFQAQGHPPSLFPPKAKSNQPKSLEDLIFESLPENASHKLEVRVVRSSPPSSQFKA 286 Query: 388 KAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFF----PLEPSAP 426 +++++ YQ + + P TP F PLE P Sbjct: 287 TLLESYQVYKRYQMVIHKNPPDTPTESQFTRFLCSSPLEAETP 329 >gi|119220605 ubiquitin specific protease 10 [Homo sapiens] Length = 798 Score = 35.4 bits (80), Expect = 0.15 Identities = 31/119 (26%), Positives = 47/119 (39%), Gaps = 18/119 (15%) Query: 277 YWNKPEPQPPYTAASAQFRRASFMGSTFN-------ISLNKEEMEFQPNQEDEEDAHAGI 329 + N P P P A + R G+ F +++NK + + QED E+ Sbjct: 472 FTNMPVPPKPRQALGDKIVRDIRPGAAFEPTYIYRLLTVNKSSLSEKGRQEDAEE----- 526 Query: 330 IGRFLGLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHKA--AKQNVRGQEDNKAWK 386 +LG + H N + KLL P E L PKNH +Q +G+ W+ Sbjct: 527 ---YLGFILNGLHEEMLNLK-KLLSPSNEKLTISNGPKNHSVNEEEQEEQGEGSEDEWE 581 >gi|61675704 hypothetical protein LOC347487 [Homo sapiens] Length = 361 Score = 34.3 bits (77), Expect = 0.34 Identities = 47/173 (27%), Positives = 72/173 (41%), Gaps = 26/173 (15%) Query: 343 PPRANSRTKLLWPKR--ESLLHEGLPKNHKAAKQNVRGQED-----NKAWKLKAVDAFKS 395 P A T+ +PKR +S + L K+ K + +G + + A KL + D Sbjct: 149 PNSAGKLTRPSYPKRSSKSSCSKKLSKSSHLEKAHKKGSLEKLCKLDYACKLASSDKPVR 208 Query: 396 APLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFEL 455 P +P Y S PQ +SP+ F P E + P K + ++VS G L Sbjct: 209 PPQLFKPLYSSHPQNEISPSKPFGPQELAKPPKHFN---------PKRSVSLGRA---AL 256 Query: 456 LSESDGALMEHPEVSQVRRKTVEFNLTDMPEIPENHLKEPLEQSPTNIHTTLK 508 LS S+ A E Q +K T P + N + E E++ N+H + K Sbjct: 257 LSNSELA-----ETCQPYKKKHLVAKTYRPLV--NDISEAKEKNTQNLHVSSK 302 >gi|157785645 SPEG complex locus [Homo sapiens] Length = 3267 Score = 34.3 bits (77), Expect = 0.34 Identities = 35/140 (25%), Positives = 54/140 (38%), Gaps = 18/140 (12%) Query: 366 PKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPSA 425 P ++ + K VRG +D+ A A + AP+ RP P +P S P P P+ Sbjct: 2758 PFSNSSEKVFVRGTQDSSAVPSAA---HQEAPVTSRPARARPPDSPTSLAPPLAPAAPTP 2814 Query: 426 PSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFNLTDMP 485 PS + S T S A S + A+ P+ R + ++ P Sbjct: 2815 PS-------VTVSPSSPPTPPSQALSSLK-------AVGPPPQTPPRRHRGLQAARPAEP 2860 Query: 486 EIPENHLKEPLEQSPTNIHT 505 +P H+ P E P + T Sbjct: 2861 TLPSTHV-TPSEPKPFVLDT 2879 >gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 isoform 1 [Homo sapiens] Length = 1599 Score = 31.6 bits (70), Expect = 2.2 Identities = 26/141 (18%), Positives = 53/141 (37%), Gaps = 5/141 (3%) Query: 366 PKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPG-----YYSAPQTPLSPTPMFFP 420 P+ + G+ A ++ D + A + RPG + + P SP+P P Sbjct: 209 PQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP 268 Query: 421 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN 480 P ++ + ++ T+ ++S + E+ PE + + +E Sbjct: 269 SPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVE 328 Query: 481 LTDMPEIPENHLKEPLEQSPT 501 +T +PE+ Q+PT Sbjct: 329 VTLSKPVPESEFSSSPLQAPT 349 >gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 isoform 2 [Homo sapiens] Length = 1512 Score = 31.6 bits (70), Expect = 2.2 Identities = 26/141 (18%), Positives = 53/141 (37%), Gaps = 5/141 (3%) Query: 366 PKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPG-----YYSAPQTPLSPTPMFFP 420 P+ + G+ A ++ D + A + RPG + + P SP+P P Sbjct: 122 PQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP 181 Query: 421 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN 480 P ++ + ++ T+ ++S + E+ PE + + +E Sbjct: 182 SPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVE 241 Query: 481 LTDMPEIPENHLKEPLEQSPT 501 +T +PE+ Q+PT Sbjct: 242 VTLSKPVPESEFSSSPLQAPT 262 >gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 isoform 3 [Homo sapiens] Length = 1435 Score = 31.6 bits (70), Expect = 2.2 Identities = 26/141 (18%), Positives = 53/141 (37%), Gaps = 5/141 (3%) Query: 366 PKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPG-----YYSAPQTPLSPTPMFFP 420 P+ + G+ A ++ D + A + RPG + + P SP+P P Sbjct: 45 PQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP 104 Query: 421 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN 480 P ++ + ++ T+ ++S + E+ PE + + +E Sbjct: 105 SPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVE 164 Query: 481 LTDMPEIPENHLKEPLEQSPT 501 +T +PE+ Q+PT Sbjct: 165 VTLSKPVPESEFSSSPLQAPT 185 >gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 isoform 1 [Homo sapiens] Length = 1599 Score = 31.6 bits (70), Expect = 2.2 Identities = 26/141 (18%), Positives = 53/141 (37%), Gaps = 5/141 (3%) Query: 366 PKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPG-----YYSAPQTPLSPTPMFFP 420 P+ + G+ A ++ D + A + RPG + + P SP+P P Sbjct: 209 PQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP 268 Query: 421 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN 480 P ++ + ++ T+ ++S + E+ PE + + +E Sbjct: 269 SPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVE 328 Query: 481 LTDMPEIPENHLKEPLEQSPT 501 +T +PE+ Q+PT Sbjct: 329 VTLSKPVPESEFSSSPLQAPT 349 >gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 isoform 4 [Homo sapiens] Length = 1403 Score = 31.6 bits (70), Expect = 2.2 Identities = 26/141 (18%), Positives = 53/141 (37%), Gaps = 5/141 (3%) Query: 366 PKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPG-----YYSAPQTPLSPTPMFFP 420 P+ + G+ A ++ D + A + RPG + + P SP+P P Sbjct: 13 PQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP 72 Query: 421 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN 480 P ++ + ++ T+ ++S + E+ PE + + +E Sbjct: 73 SPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVE 132 Query: 481 LTDMPEIPENHLKEPLEQSPT 501 +T +PE+ Q+PT Sbjct: 133 VTLSKPVPESEFSSSPLQAPT 153 >gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] Length = 1488 Score = 30.8 bits (68), Expect = 3.8 Identities = 35/167 (20%), Positives = 54/167 (32%), Gaps = 28/167 (16%) Query: 251 VDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFMGSTFNISLNK 310 +D ++ S+++ HQ +P P P P Y + +SF+GS F K Sbjct: 1162 LDSTIEGSVISSPRPHQRMPPPPP------PPPPEEYKSQRPVSNSSSFLGSLFGSKRGK 1215 Query: 311 EEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHK 370 + P + A + H HH +S L +L +G K Sbjct: 1216 GPFQMPPPPTGQASASSSSAS---STHHHHHHHHHGHSHGGL------GVLPDGQSKLQA 1266 Query: 371 AAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPM 417 Q +G + P Y P S P P P P+ Sbjct: 1267 LHAQYCQGPG-------------PAPPPYLPPQQPSLPPPPQQPPPL 1300 >gi|27886651 potassium voltage-gated channel, subfamily H, member 6 isoform 2 [Homo sapiens] Length = 905 Score = 30.4 bits (67), Expect = 4.9 Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 11/86 (12%) Query: 303 TFNISLNKEEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESLLH 362 TFN+ + P Q H G FL D PP + S LWP+ LL Sbjct: 658 TFNLRDAAGGLHSSPRQAPGSQDHQGF---FLSDNQSDAAPPLSISDASGLWPE---LLQ 711 Query: 363 EGLPKNHKAAKQNVRGQEDNKAWKLK 388 E +P H QED W LK Sbjct: 712 E-MPPRHSPQSP----QEDPDCWPLK 732 >gi|83367077 mucin 16 [Homo sapiens] Length = 14507 Score = 30.0 bits (66), Expect = 6.4 Identities = 36/164 (21%), Positives = 56/164 (34%), Gaps = 28/164 (17%) Query: 391 DAFKSAPLYQRPGYYSAPQTPL----SPTPMFFPLEPSAPSKLHSVTGIDT--------K 438 D K++P + Q PL SP+P+ L+ + S L SVT + T Sbjct: 6206 DVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSLVSVTSVPTPTLAKITDM 6265 Query: 439 DKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFNLTDMPEIPENHLKEPLEQ 498 D +L+ V+ + L+ S+ H + T Sbjct: 6266 DTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSINTAVANVGTT---------------S 6310 Query: 499 SPTNIHTTLKDHMDPYWALENRSVLHLNQGHCIALCPTPASLAL 542 SP + T+ DPY A + V+ G I P S A+ Sbjct: 6311 SPNEFYFTVSPDSDPYKA-TSAVVITSTSGDSIVSTSMPRSSAM 6353 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 29.6 bits (65), Expect = 8.4 Identities = 31/120 (25%), Positives = 45/120 (37%), Gaps = 21/120 (17%) Query: 366 PKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFF------ 419 PK A KQ++ KA + K PL ++P + +P P Sbjct: 684 PKKDAAPKQDLS----------KAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733 Query: 420 -PLEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVE 478 P EPS PS+ D K K K V K + +L+S S S+V+ + E Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMV----KPTTDLVSSSSATTKPDIPSSKVQSQAEE 789 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 29.6 bits (65), Expect = 8.4 Identities = 31/120 (25%), Positives = 45/120 (37%), Gaps = 21/120 (17%) Query: 366 PKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFF------ 419 PK A KQ++ KA + K PL ++P + +P P Sbjct: 684 PKKDAAPKQDLS----------KAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733 Query: 420 -PLEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVE 478 P EPS PS+ D K K K V K + +L+S S S+V+ + E Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMV----KPTTDLVSSSSATTKPDIPSSKVQSQAEE 789 >gi|24307933 transcription factor EB [Homo sapiens] Length = 476 Score = 29.6 bits (65), Expect = 8.4 Identities = 21/89 (23%), Positives = 35/89 (39%) Query: 373 KQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSV 432 ++ + +E + + +AV + Q+ P TP TP+ F P P ++ V Sbjct: 13 REQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKV 72 Query: 433 TGIDTKDKSLKTVSSGAKKSFELLSESDG 461 S S +K E LSE+ G Sbjct: 73 QSYLENPTSYHLQQSQHQKVREYLSETYG 101 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.137 0.436 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,642,342 Number of Sequences: 37866 Number of extensions: 1227927 Number of successful extensions: 3415 Number of sequences better than 10.0: 23 Number of HSP's better than 10.0 without gapping: 7 Number of HSP's successfully gapped in prelim test: 16 Number of HSP's that attempted gapping in prelim test: 3392 Number of HSP's gapped (non-prelim): 37 length of query: 604 length of database: 18,247,518 effective HSP length: 108 effective length of query: 496 effective length of database: 14,157,990 effective search space: 7022363040 effective search space used: 7022363040 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.