Guide to the Human Genome
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Search of human proteins with 212286179

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|212286179 parvin, gamma [Homo sapiens]
         (331 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|212286181 parvin, gamma [Homo sapiens]                             653   0.0  
gi|212286179 parvin, gamma [Homo sapiens]                             653   0.0  
gi|11545879 parvin, gamma [Homo sapiens]                              653   0.0  
gi|51477696 parvin, beta isoform a [Homo sapiens]                     261   5e-70
gi|20127528 parvin, beta isoform b [Homo sapiens]                     261   5e-70
gi|8922673 parvin, alpha [Homo sapiens]                               253   2e-67
gi|12025678 actinin, alpha 4 [Homo sapiens]                            47   2e-05
gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]                 45   1e-04
gi|194097350 actinin, alpha 1 isoform a [Homo sapiens]                 45   1e-04
gi|4501891 actinin, alpha 1 isoform b [Homo sapiens]                   45   1e-04
gi|83816971 DIX domain containing 1 isoform a [Homo sapiens]           44   3e-04
gi|126116596 asp (abnormal spindle)-like, microcephaly associate...    43   4e-04
gi|188595687 gamma filamin isoform b [Homo sapiens]                    38   0.011
gi|116805322 gamma filamin isoform a [Homo sapiens]                    38   0.011
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [...    38   0.014
gi|160420317 filamin A, alpha isoform 2 [Homo sapiens]                 37   0.024
gi|116063573 filamin A, alpha isoform 1 [Homo sapiens]                 37   0.024
gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo ...    37   0.024
gi|105990514 filamin B, beta (actin binding protein 278) [Homo s...    37   0.032
gi|9910266 kinesin family member 15 [Homo sapiens]                     37   0.032
gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]           35   0.071
gi|221316624 dystonin isoform 4 [Homo sapiens]                         35   0.071
gi|221316622 dystonin isoform 3 [Homo sapiens]                         35   0.071
gi|221316618 dystonin isoform 2 [Homo sapiens]                         35   0.071
gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo ...    35   0.071
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                         35   0.071
gi|120953251 neuron navigator 3 [Homo sapiens]                         35   0.071
gi|33188445 microfilament and actin filament cross-linker protei...    35   0.093
gi|5032281 dystrophin Dp427c isoform [Homo sapiens]                    34   0.21 
gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens]                   34   0.21 

>gi|212286181 parvin, gamma [Homo sapiens]
          Length = 331

 Score =  653 bits (1685), Expect = 0.0
 Identities = 331/331 (100%), Positives = 331/331 (100%)

Query: 1   MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLP 60
           MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLP
Sbjct: 1   MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLP 60

Query: 61  EHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLE 120
           EHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLE
Sbjct: 61  EHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLE 120

Query: 121 EWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLV 180
           EWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLV
Sbjct: 121 EWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLV 180

Query: 181 EQLTEYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFAD 240
           EQLTEYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFAD
Sbjct: 181 EQLTEYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFAD 240

Query: 241 GVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNK 300
           GVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNK
Sbjct: 241 GVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNK 300

Query: 301 DAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN 331
           DAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN
Sbjct: 301 DAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN 331


>gi|212286179 parvin, gamma [Homo sapiens]
          Length = 331

 Score =  653 bits (1685), Expect = 0.0
 Identities = 331/331 (100%), Positives = 331/331 (100%)

Query: 1   MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLP 60
           MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLP
Sbjct: 1   MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLP 60

Query: 61  EHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLE 120
           EHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLE
Sbjct: 61  EHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLE 120

Query: 121 EWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLV 180
           EWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLV
Sbjct: 121 EWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLV 180

Query: 181 EQLTEYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFAD 240
           EQLTEYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFAD
Sbjct: 181 EQLTEYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFAD 240

Query: 241 GVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNK 300
           GVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNK
Sbjct: 241 GVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNK 300

Query: 301 DAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN 331
           DAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN
Sbjct: 301 DAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN 331


>gi|11545879 parvin, gamma [Homo sapiens]
          Length = 331

 Score =  653 bits (1685), Expect = 0.0
 Identities = 331/331 (100%), Positives = 331/331 (100%)

Query: 1   MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLP 60
           MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLP
Sbjct: 1   MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLP 60

Query: 61  EHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLE 120
           EHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLE
Sbjct: 61  EHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLE 120

Query: 121 EWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLV 180
           EWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLV
Sbjct: 121 EWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLV 180

Query: 181 EQLTEYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFAD 240
           EQLTEYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFAD
Sbjct: 181 EQLTEYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFAD 240

Query: 241 GVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNK 300
           GVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNK
Sbjct: 241 GVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNK 300

Query: 301 DAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN 331
           DAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN
Sbjct: 301 DAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN 331


>gi|51477696 parvin, beta isoform a [Homo sapiens]
          Length = 397

 Score =  261 bits (668), Expect = 5e-70
 Identities = 136/301 (45%), Positives = 198/301 (65%), Gaps = 5/301 (1%)

Query: 19  PAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLPEHIVVRSLEEDMFDGLIL 78
           P + +L +  ++  + PTS++DPKF+EL KVL++WIN  L+ E I+V+ LEED++DG +L
Sbjct: 95  PEDTQLEENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVL 154

Query: 79  HHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLEEWQAKWSVESIFNKDLLS 138
             L ++LA  KL   ++  +   QK KL  VLEAV+  L+   W  +WSV+SI  K+L++
Sbjct: 155 QKLLEKLAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVA 214

Query: 139 TLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLVEQL---TEYSTDKDEPPK 195
            LHLLV+LA  F+  + LP +V V+V+ +   +  L S  + E+L   TE    + E  +
Sbjct: 215 ILHLLVSLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFE--R 272

Query: 196 DVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFF 255
           D FD LF  AP+K++ VK++++ FVN+ L++L L V  L+TQFADGV L+LL+G LE +F
Sbjct: 273 DAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYF 332

Query: 256 LHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLFCK 315
           + L  FYLTP S  + +HNV+ A EL+ D GL      PED+VN D KSTLRVLY LF K
Sbjct: 333 VPLHHFYLTPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTK 392

Query: 316 H 316
           +
Sbjct: 393 Y 393


>gi|20127528 parvin, beta isoform b [Homo sapiens]
          Length = 364

 Score =  261 bits (668), Expect = 5e-70
 Identities = 136/301 (45%), Positives = 198/301 (65%), Gaps = 5/301 (1%)

Query: 19  PAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLPEHIVVRSLEEDMFDGLIL 78
           P + +L +  ++  + PTS++DPKF+EL KVL++WIN  L+ E I+V+ LEED++DG +L
Sbjct: 62  PEDTQLEENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVL 121

Query: 79  HHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLEEWQAKWSVESIFNKDLLS 138
             L ++LA  KL   ++  +   QK KL  VLEAV+  L+   W  +WSV+SI  K+L++
Sbjct: 122 QKLLEKLAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVA 181

Query: 139 TLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLVEQL---TEYSTDKDEPPK 195
            LHLLV+LA  F+  + LP +V V+V+ +   +  L S  + E+L   TE    + E  +
Sbjct: 182 ILHLLVSLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFE--R 239

Query: 196 DVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFF 255
           D FD LF  AP+K++ VK++++ FVN+ L++L L V  L+TQFADGV L+LL+G LE +F
Sbjct: 240 DAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYF 299

Query: 256 LHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLFCK 315
           + L  FYLTP S  + +HNV+ A EL+ D GL      PED+VN D KSTLRVLY LF K
Sbjct: 300 VPLHHFYLTPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTK 359

Query: 316 H 316
           +
Sbjct: 360 Y 360


>gi|8922673 parvin, alpha [Homo sapiens]
          Length = 372

 Score =  253 bits (645), Expect = 2e-67
 Identities = 131/301 (43%), Positives = 199/301 (66%), Gaps = 5/301 (1%)

Query: 19  PAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLPEHIVVRSLEEDMFDGLIL 78
           P +  L +   +  + P SR DPK +EL KVL++WIN  L+ E I+V+ L ED++DG +L
Sbjct: 70  PEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVL 129

Query: 79  HHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLEEWQAKWSVESIFNKDLLS 138
             LF++L + KL   ++  +  +QK KL  VLE +N +L+L     KW+V+S+  K L++
Sbjct: 130 QKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVA 189

Query: 139 TLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLVEQL---TEYSTDKDEPPK 195
            LHLLVAL++ F+  + LP +V ++V+ ++  +  L+S ++ E++   TE  + + E  +
Sbjct: 190 ILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHE--R 247

Query: 196 DVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFF 255
           D FD LF  AP+K+N VK+ ++ FVN+ L++L L V  L+TQFADGV L+LL+G LEG+F
Sbjct: 248 DAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYF 307

Query: 256 LHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLFCK 315
           + L  F+LTP+S  + + NV+ A EL++D GL      PEDIVN D KSTLRVLY LF K
Sbjct: 308 VPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTK 367

Query: 316 H 316
           +
Sbjct: 368 Y 368


>gi|12025678 actinin, alpha 4 [Homo sapiens]
          Length = 911

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 30/121 (24%), Positives = 58/121 (47%), Gaps = 3/121 (2%)

Query: 195 KDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGF 254
           +D +D    L P      ++    + N  L + G  ++N+D  F DG+ L+LL+  + G 
Sbjct: 35  EDDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGE 94

Query: 255 FLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLFC 314
            L   E           ++NV  AL+ +  +G+    +  E+IV+ +AK TL +++ +  
Sbjct: 95  RLPKPE---RGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIIL 151

Query: 315 K 315
           +
Sbjct: 152 R 152



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 48/208 (23%), Positives = 83/208 (39%), Gaps = 33/208 (15%)

Query: 40  DPKFEELQ-KVLMEWINATLLPEHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALT 98
           DP +E+ Q K    W N+ L      + +++ED  DGL L  L + ++  +L   +    
Sbjct: 45  DPAWEKQQRKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPE---R 101

Query: 99  ATSQKHKLTVVLEAVNRSLQLEEWQAKWSVESIFNKDLLSTLHLLVALAKRFQ-PDLSLP 157
              + HK+  V +A++              E I + +   TL ++  +  RF   D+S+ 
Sbjct: 102 GKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVE 161

Query: 158 -------------------TNVQVEVITIESTKSGLKSEKLVE----QLTEYSTDKDEPP 194
                               NV V+   I S K GL    L+     +L EY   + + P
Sbjct: 162 ETSAKEGLLLWCQRKTAPYKNVNVQNFHI-SWKDGLAFNALIHRHRPELIEYDKLRKDDP 220

Query: 195 KDVFDELFKLAPEKVNAVK----EAIVN 218
               +  F++A + ++  K    E IVN
Sbjct: 221 VTNLNNAFEVAEKYLDIPKMLDAEDIVN 248


>gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]
          Length = 887

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 28/122 (22%), Positives = 57/122 (46%), Gaps = 3/122 (2%)

Query: 194 PKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEG 253
           P++ +D    L P      ++    + N  L + G  ++N++  F DG+ L+LL+  + G
Sbjct: 15  PEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISG 74

Query: 254 FFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLF 313
             L   E           + NV  AL+ +  +G+    +  E+IV+ + K TL +++ + 
Sbjct: 75  ERLAKPE---RGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTII 131

Query: 314 CK 315
            +
Sbjct: 132 LR 133



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 27/112 (24%), Positives = 50/112 (44%), Gaps = 4/112 (3%)

Query: 40  DPKFEELQ-KVLMEWINATLLPEHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALT 98
           DP +E+ Q K    W N+ L      + ++EED  DGL L  L + ++  +L   +    
Sbjct: 26  DPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPE---R 82

Query: 99  ATSQKHKLTVVLEAVNRSLQLEEWQAKWSVESIFNKDLLSTLHLLVALAKRF 150
              + HK++ V +A++              E I + ++  TL ++  +  RF
Sbjct: 83  GKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRF 134


>gi|194097350 actinin, alpha 1 isoform a [Homo sapiens]
          Length = 914

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 28/122 (22%), Positives = 57/122 (46%), Gaps = 3/122 (2%)

Query: 194 PKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEG 253
           P++ +D    L P      ++    + N  L + G  ++N++  F DG+ L+LL+  + G
Sbjct: 15  PEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISG 74

Query: 254 FFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLF 313
             L   E           + NV  AL+ +  +G+    +  E+IV+ + K TL +++ + 
Sbjct: 75  ERLAKPE---RGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTII 131

Query: 314 CK 315
            +
Sbjct: 132 LR 133



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 27/112 (24%), Positives = 50/112 (44%), Gaps = 4/112 (3%)

Query: 40  DPKFEELQ-KVLMEWINATLLPEHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALT 98
           DP +E+ Q K    W N+ L      + ++EED  DGL L  L + ++  +L   +    
Sbjct: 26  DPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPE---R 82

Query: 99  ATSQKHKLTVVLEAVNRSLQLEEWQAKWSVESIFNKDLLSTLHLLVALAKRF 150
              + HK++ V +A++              E I + ++  TL ++  +  RF
Sbjct: 83  GKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRF 134


>gi|4501891 actinin, alpha 1 isoform b [Homo sapiens]
          Length = 892

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 28/122 (22%), Positives = 57/122 (46%), Gaps = 3/122 (2%)

Query: 194 PKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEG 253
           P++ +D    L P      ++    + N  L + G  ++N++  F DG+ L+LL+  + G
Sbjct: 15  PEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISG 74

Query: 254 FFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLF 313
             L   E           + NV  AL+ +  +G+    +  E+IV+ + K TL +++ + 
Sbjct: 75  ERLAKPE---RGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTII 131

Query: 314 CK 315
            +
Sbjct: 132 LR 133



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 27/112 (24%), Positives = 50/112 (44%), Gaps = 4/112 (3%)

Query: 40  DPKFEELQ-KVLMEWINATLLPEHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALT 98
           DP +E+ Q K    W N+ L      + ++EED  DGL L  L + ++  +L   +    
Sbjct: 26  DPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPE---R 82

Query: 99  ATSQKHKLTVVLEAVNRSLQLEEWQAKWSVESIFNKDLLSTLHLLVALAKRF 150
              + HK++ V +A++              E I + ++  TL ++  +  RF
Sbjct: 83  GKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRF 134


>gi|83816971 DIX domain containing 1 isoform a [Homo sapiens]
          Length = 683

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 34/120 (28%), Positives = 62/120 (51%), Gaps = 8/120 (6%)

Query: 44  EELQKVLMEWINATLLPEHIV--VRSLEEDMFDGLILHHLFQRLAALKLEAEDIAL-TAT 100
           E+  +  + W+NA L     V  V+ L +D+ DG+IL +L + +A  KL    ++     
Sbjct: 20  EQQLQAYVAWVNAQLKKRPAVKPVQDLRQDLRDGVILAYLIEIVAGEKLSGVQLSPGNQQ 79

Query: 101 SQKHKLTVVLEAV-NRSLQLEEWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTN 159
             K+ +  VL+ V ++ +++ +  AK     I + +L S + L++ALA  F+P  S   N
Sbjct: 80  EMKNNVEKVLQFVASKKIRMHQTSAK----DIVDGNLKSIMRLVLALAAHFKPGSSRTVN 135



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 4/101 (3%)

Query: 214 EAIVNFVNQKLDRLGL--SVQNLDTQFADGVILLLLIGQLEGFFLHLKEFYLTPNSPAEM 271
           +A V +VN +L +      VQ+L     DGVIL  LI  + G    L    L+P +  EM
Sbjct: 24  QAYVAWVNAQLKKRPAVKPVQDLRQDLRDGVILAYLIEIVAGE--KLSGVQLSPGNQQEM 81

Query: 272 LHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGL 312
            +NV   L+ +  + +     S +DIV+ + KS +R++  L
Sbjct: 82  KNNVEKVLQFVASKKIRMHQTSAKDIVDGNLKSIMRLVLAL 122


>gi|126116596 asp (abnormal spindle)-like, microcephaly associated
            [Homo sapiens]
          Length = 3477

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 45/165 (27%), Positives = 81/165 (49%), Gaps = 27/165 (16%)

Query: 96   ALTATSQKHKLTVVLEAV-NRSLQLEEWQAKWSVESIFNKDLLS-----TLHLLVALAKR 149
            A++   + H + +VL+ + +R ++L +        +I +KD++      TL LL  +A  
Sbjct: 999  AISRLQKMHNVDIVLQVLKSRGIELSDEHGN----TILSKDIVDRHREKTLRLLWKIAFA 1054

Query: 150  FQPDLSLPTN-VQVEVITIESTKSGLKSEKLVEQLTEYSTDKDEPPKDV-----FDELFK 203
            FQ D+SL  + ++ E+  ++ TKS  K+  L+   ++   +K +  +D      + E  K
Sbjct: 1055 FQVDISLNLDQLKEEIAFLKHTKSIKKTISLLSCHSDDLINKKKGKRDSGSFEQYSENIK 1114

Query: 204  LAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLI 248
            L  + VNAV      F N+K       V+N    F+DG +L  LI
Sbjct: 1115 LLMDWVNAV----CAFYNKK-------VENFTVSFSDGRVLCYLI 1148



 Score = 36.6 bits (83), Expect = 0.032
 Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 5/99 (5%)

Query: 217  VNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVT 276
            VN V    D    +V NL      GV L+  +  L   +   K+  +   S  + +HNV 
Sbjct: 951  VNHVQTPFDEFDFAVTNLAVDLQCGVRLVRTMELLTQNWDLSKKLRIPAISRLQKMHNVD 1010

Query: 277  LALELLKDEGL-----LSCPVSPEDIVNKDAKSTLRVLY 310
            + L++LK  G+         +  +DIV++  + TLR+L+
Sbjct: 1011 IVLQVLKSRGIELSDEHGNTILSKDIVDRHREKTLRLLW 1049


>gi|188595687 gamma filamin isoform b [Homo sapiens]
          Length = 2692

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 34/129 (26%), Positives = 62/129 (48%), Gaps = 3/129 (2%)

Query: 189 DKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLI 248
           + DE P    D L + AP K    +     + N+ L  +G  + +L    +DG+ L+ L+
Sbjct: 17  ETDEMPSTEKD-LAEDAPWK-KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALL 74

Query: 249 GQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRV 308
             L    ++ K F+  PN     L NV++ALE L+ E +    +  + IV+ + K  L +
Sbjct: 75  EVLSQKRMYRK-FHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGL 133

Query: 309 LYGLFCKHT 317
           ++ L   ++
Sbjct: 134 IWTLILHYS 142


>gi|116805322 gamma filamin isoform a [Homo sapiens]
          Length = 2725

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 34/129 (26%), Positives = 62/129 (48%), Gaps = 3/129 (2%)

Query: 189 DKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLI 248
           + DE P    D L + AP K    +     + N+ L  +G  + +L    +DG+ L+ L+
Sbjct: 17  ETDEMPSTEKD-LAEDAPWK-KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALL 74

Query: 249 GQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRV 308
             L    ++ K F+  PN     L NV++ALE L+ E +    +  + IV+ + K  L +
Sbjct: 75  EVLSQKRMYRK-FHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGL 133

Query: 309 LYGLFCKHT 317
           ++ L   ++
Sbjct: 134 IWTLILHYS 142


>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1
           [Homo sapiens]
          Length = 2564

 Score = 37.7 bits (86), Expect = 0.014
 Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 9/115 (7%)

Query: 204 LAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFFLHLKEFYL 263
           LA E+    K+    +VN  L R+G  + +L     DG +L  L+  L G      E   
Sbjct: 55  LADEREAVQKKTFTKWVNSHLARVGCHIGDLYVDLRDGFVLTRLLEVLSG------EQLP 108

Query: 264 TPNSPAEMLH---NVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLFCK 315
            P      +H   NV  AL+ LK++ +    V   DIV+ + + TL +++ +  +
Sbjct: 109 RPTRGRMRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHRLTLGLVWTIILR 163


>gi|160420317 filamin A, alpha isoform 2 [Homo sapiens]
          Length = 2647

 Score = 37.0 bits (84), Expect = 0.024
 Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 1/105 (0%)

Query: 213 KEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFFLHLKEFYLTPNSPAEML 272
           +     + N+ L  +   + NL T  +DG+ L+ L+  L    +H K     P      L
Sbjct: 46  QNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQ-RPTFRQMQL 104

Query: 273 HNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLFCKHT 317
            NV++ALE L  E +    +  + IV+ + K  L +++ L   ++
Sbjct: 105 ENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYS 149


>gi|116063573 filamin A, alpha isoform 1 [Homo sapiens]
          Length = 2639

 Score = 37.0 bits (84), Expect = 0.024
 Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 1/105 (0%)

Query: 213 KEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFFLHLKEFYLTPNSPAEML 272
           +     + N+ L  +   + NL T  +DG+ L+ L+  L    +H K     P      L
Sbjct: 46  QNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQ-RPTFRQMQL 104

Query: 273 HNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLFCKHT 317
            NV++ALE L  E +    +  + IV+ + K  L +++ L   ++
Sbjct: 105 ENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYS 149


>gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo
           sapiens]
          Length = 2364

 Score = 37.0 bits (84), Expect = 0.024
 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 9/115 (7%)

Query: 204 LAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFFLHLKEFYL 263
           LA E+    K+    +VN  L R+   + +L T   DG +L+ L+  L G      E   
Sbjct: 48  LADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSG------ERLP 101

Query: 264 TPNSPAEMLH---NVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLFCK 315
            P      +H   NV  AL+ LK++ +    +   DIV+ + + TL +++ +  +
Sbjct: 102 KPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILR 156


>gi|105990514 filamin B, beta (actin binding protein 278) [Homo
           sapiens]
          Length = 2602

 Score = 36.6 bits (83), Expect = 0.032
 Identities = 25/105 (23%), Positives = 50/105 (47%), Gaps = 1/105 (0%)

Query: 213 KEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFFLHLKEFYLTPNSPAEML 272
           +     + N+ L  +   + NL T  +DG+ L+ L+  L    ++ K ++  P      L
Sbjct: 19  QNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRK-YHQRPTFRQMQL 77

Query: 273 HNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLFCKHT 317
            NV++ALE L  E +    +  + IV+ + K  L +++ L   ++
Sbjct: 78  ENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILHYS 122


>gi|9910266 kinesin family member 15 [Homo sapiens]
          Length = 1388

 Score = 36.6 bits (83), Expect = 0.032
 Identities = 46/199 (23%), Positives = 86/199 (43%), Gaps = 15/199 (7%)

Query: 15   GVEPPAEEELSKGGKKKYLPPTSRK-DPKFEELQKVLMEWINATLLPEHIVVRSLEEDMF 73
            G+   A+EEL+K  K+  +     K + K EE+++   E+       EH++  + E+   
Sbjct: 1084 GLLQSAQEELTK--KEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDSAAEDPQS 1141

Query: 74   DGLILH---HLFQRLAALKLEAEDIALTATSQKHKLTVV--------LEAVNRSLQLEEW 122
                 H   HL + L   + E ED   + TS +H +T +         E +    QL E 
Sbjct: 1142 PKTPPHFQTHLAKLLETQEQEIEDGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLREM 1201

Query: 123  Q-AKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLVE 181
            +  +   + +  K+ L    L     ++   D + P N Q++    ES K  L   K+VE
Sbjct: 1202 ENLRLESQQLIEKNWLLQGQLDDIKRQKENSDQNHPDNQQLKNEQEESIKERLAKSKIVE 1261

Query: 182  QLTEYSTDKDEPPKDVFDE 200
            ++ +   D +E    ++++
Sbjct: 1262 EMLKMKADLEEVQSALYNK 1280


>gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]
          Length = 2390

 Score = 35.4 bits (80), Expect = 0.071
 Identities = 35/138 (25%), Positives = 60/138 (43%), Gaps = 11/138 (7%)

Query: 183 LTEYSTDKDEPPKDVFDE--LFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFAD 240
           L +   D D     +F+   +  LA E+    K+    +VN  L R+   V +L +   D
Sbjct: 28  LPDSDWDNDSSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVTCRVGDLYSDLRD 87

Query: 241 GVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLH---NVTLALELLKDEGLLSCPVSPEDI 297
           G  LL L+  L G      E    P      +H   NV  AL+ LK++ +    +   DI
Sbjct: 88  GRNLLRLLEVLSG------EILPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDI 141

Query: 298 VNKDAKSTLRVLYGLFCK 315
           V+ + + TL +++ +  +
Sbjct: 142 VDGNHRLTLGLVWTIILR 159


>gi|221316624 dystonin isoform 4 [Homo sapiens]
          Length = 5526

 Score = 35.4 bits (80), Expect = 0.071
 Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 12/114 (10%)

Query: 201 LFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFFLHLKE 260
           + ++A E+    K+    ++NQ L ++   V +L     DG  L+ L+  L G  L    
Sbjct: 55  VLRIADERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTL---- 110

Query: 261 FYLTPNSPAEM----LHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLY 310
               P     M    L NV +AL+ LK   +    +  +DI + + K TL +++
Sbjct: 111 ----PREKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIW 160


>gi|221316622 dystonin isoform 3 [Homo sapiens]
          Length = 5537

 Score = 35.4 bits (80), Expect = 0.071
 Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 12/114 (10%)

Query: 201 LFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFFLHLKE 260
           + ++A E+    K+    ++NQ L ++   V +L     DG  L+ L+  L G  L    
Sbjct: 66  VLRIADERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTL---- 121

Query: 261 FYLTPNSPAEM----LHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLY 310
               P     M    L NV +AL+ LK   +    +  +DI + + K TL +++
Sbjct: 122 ----PREKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIW 171


>gi|221316618 dystonin isoform 2 [Homo sapiens]
          Length = 5675

 Score = 35.4 bits (80), Expect = 0.071
 Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 12/114 (10%)

Query: 201 LFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFFLHLKE 260
           + ++A E+    K+    ++NQ L ++   V +L     DG  L+ L+  L G  L    
Sbjct: 204 VLRIADERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTL---- 259

Query: 261 FYLTPNSPAEM----LHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLY 310
               P     M    L NV +AL+ LK   +    +  +DI + + K TL +++
Sbjct: 260 ----PREKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIW 309


>gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo
           sapiens]
          Length = 2155

 Score = 35.4 bits (80), Expect = 0.071
 Identities = 29/116 (25%), Positives = 53/116 (45%), Gaps = 9/116 (7%)

Query: 203 KLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFFLHLKEFY 262
           +L  E+    K+    +VN  L R+   + +L T   DG +L+ L+  L G      E  
Sbjct: 34  QLQDEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSG------ERL 87

Query: 263 LTPNSPAEMLH---NVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLFCK 315
             P      +H   NV  AL+ LK++ +    +   DIV+ + + TL +++ +  +
Sbjct: 88  PKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILR 143


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score = 35.4 bits (80), Expect = 0.071
 Identities = 29/123 (23%), Positives = 54/123 (43%), Gaps = 12/123 (9%)

Query: 192 EPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQL 251
           +P + + +E+  L  E+    K+    +VN+ L +    + +L     DG  L+ L+  L
Sbjct: 2   DPSRAIQNEISSLKDERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVL 61

Query: 252 EGFFLHLKEFYLTPNSPAEM----LHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLR 307
            G  L        P     M    L NV +AL+ L+   +    +  +DI + + K TL 
Sbjct: 62  SGDSL--------PREKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLG 113

Query: 308 VLY 310
           +++
Sbjct: 114 LIW 116


>gi|120953251 neuron navigator 3 [Homo sapiens]
          Length = 2363

 Score = 35.4 bits (80), Expect = 0.071
 Identities = 24/94 (25%), Positives = 47/94 (50%), Gaps = 2/94 (2%)

Query: 231 VQNLDTQFADGVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSC 290
           +++L    ADGV+L  +I  +      +++    P S ++M+ NV + L  L   G+   
Sbjct: 100 IKDLQQDIADGVLLAEIIQIIANE--KVEDINGCPRSQSQMIENVDVCLSFLAARGVNVQ 157

Query: 291 PVSPEDIVNKDAKSTLRVLYGLFCKHTQKAHRDR 324
            +S E+I N + K+ L + + L     Q+ H+ +
Sbjct: 158 GLSAEEIRNGNLKAILGLFFSLSRYKQQQHHQQQ 191



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 9/111 (8%)

Query: 14   KGVEPPAEEELSKGGKKKYLPPTSRKD---------PKFEELQKVLMEWINATLLPEHIV 64
            +G E  +  + + G KK   PP+S  D         P   +L     +  +A++ P    
Sbjct: 1705 RGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNAGDCGSASMKPSQSA 1764

Query: 65   VRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNR 115
                E    +  I+  L   L   +L+  DI L A S  H L  + EA+NR
Sbjct: 1765 SAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQIREAMNR 1815



 Score = 28.5 bits (62), Expect = 8.7
 Identities = 18/66 (27%), Positives = 36/66 (54%), Gaps = 6/66 (9%)

Query: 28  GKKKYLPPTSRKDPKFEELQKVLMEWINATLLPE--HIVVRSLEEDMFDGLILHHLFQRL 85
           G+KK L   +++    +E  K+  +W N  L       +++ L++D+ DG++L  + Q +
Sbjct: 65  GEKKPLQGKAKE----KEDSKIYTDWANHYLAKSGHKRLIKDLQQDIADGVLLAEIIQII 120

Query: 86  AALKLE 91
           A  K+E
Sbjct: 121 ANEKVE 126


>gi|33188445 microfilament and actin filament cross-linker protein
           isoform a [Homo sapiens]
          Length = 5430

 Score = 35.0 bits (79), Expect = 0.093
 Identities = 28/112 (25%), Positives = 50/112 (44%), Gaps = 12/112 (10%)

Query: 203 KLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFFLHLKEFY 262
           ++A E+    K+    +VN+ L ++   + +L     DG  L+ L+  L G  L      
Sbjct: 71  RVADERDRVQKKTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKL------ 124

Query: 263 LTPNSPAEM----LHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLY 310
             P     M    L NV +AL+ LK   +    +  +DI + + K TL +++
Sbjct: 125 --PREKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIW 174



 Score = 32.0 bits (71), Expect = 0.78
 Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 5/80 (6%)

Query: 19  PAEEELSKGGKKKYLPPTSRK-----DPKFEELQKVLMEWINATLLPEHIVVRSLEEDMF 73
           P  E+  +  +   L P  R      D +    +K   +W+N  L+     +  L ED+ 
Sbjct: 48  PLHEQKKRKSQDSVLDPAERAVVRVADERDRVQKKTFTKWVNKHLMKVRKHINDLYEDLR 107

Query: 74  DGLILHHLFQRLAALKLEAE 93
           DG  L  L + L+ +KL  E
Sbjct: 108 DGHNLISLLEVLSGIKLPRE 127


>gi|5032281 dystrophin Dp427c isoform [Homo sapiens]
          Length = 3677

 Score = 33.9 bits (76), Expect = 0.21
 Identities = 27/107 (25%), Positives = 53/107 (49%), Gaps = 5/107 (4%)

Query: 207 EKVNAVKEAIVNFVNQKLDRLGLS-VQNLDTQFADGVILLLLIGQLEGFFLHLKEFYLTP 265
           E+ +  K+    +VN +  + G   ++NL +   DG  LL L+  L G  L  ++     
Sbjct: 4   EREDVQKKTFTKWVNAQFSKFGKQHIENLFSDLQDGRRLLDLLEGLTGQKLPKEK----G 59

Query: 266 NSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGL 312
           ++    L+NV  AL +L++  +    +   DIV+ + K TL +++ +
Sbjct: 60  STRVHALNNVNKALRVLQNNNVDLVNIGSTDIVDGNHKLTLGLIWNI 106


>gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens]
          Length = 3681

 Score = 33.9 bits (76), Expect = 0.21
 Identities = 27/107 (25%), Positives = 53/107 (49%), Gaps = 5/107 (4%)

Query: 207 EKVNAVKEAIVNFVNQKLDRLGLS-VQNLDTQFADGVILLLLIGQLEGFFLHLKEFYLTP 265
           E+ +  K+    +VN +  + G   ++NL +   DG  LL L+  L G  L  ++     
Sbjct: 8   EREDVQKKTFTKWVNAQFSKFGKQHIENLFSDLQDGRRLLDLLEGLTGQKLPKEK----G 63

Query: 266 NSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGL 312
           ++    L+NV  AL +L++  +    +   DIV+ + K TL +++ +
Sbjct: 64  STRVHALNNVNKALRVLQNNNVDLVNIGSTDIVDGNHKLTLGLIWNI 110


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.135    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,705,876
Number of Sequences: 37866
Number of extensions: 547762
Number of successful extensions: 1918
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 1824
Number of HSP's gapped (non-prelim): 154
length of query: 331
length of database: 18,247,518
effective HSP length: 103
effective length of query: 228
effective length of database: 14,347,320
effective search space: 3271188960
effective search space used: 3271188960
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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