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Search of human proteins with 212276096
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|212276096 leucine rich repeat (in FLII) interacting protein
1 isoform 3 [Homo sapiens]
(808 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|212276096 leucine rich repeat (in FLII) interacting protein 1... 1596 0.0
gi|212276070 leucine rich repeat (in FLII) interacting protein 1... 1535 0.0
gi|212276104 leucine rich repeat (in FLII) interacting protein 1... 1458 0.0
gi|212276088 leucine rich repeat (in FLII) interacting protein 1... 433 e-121
gi|212276078 leucine rich repeat (in FLII) interacting protein 1... 332 8e-91
gi|197276647 leucine rich repeat (in FLII) interacting protein 2... 253 5e-67
gi|5453726 leucine rich repeat (in FLII) interacting protein 2 i... 207 4e-53
gi|8923224 leucine rich repeat (in FLII) interacting protein 2 i... 202 1e-51
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 79 1e-14
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 68 3e-11
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 65 3e-10
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 64 4e-10
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 64 4e-10
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 64 4e-10
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 62 3e-09
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 61 5e-09
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 60 1e-08
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 58 3e-08
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 58 3e-08
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 57 7e-08
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 55 3e-07
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 55 3e-07
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 55 3e-07
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 55 3e-07
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 55 3e-07
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 55 3e-07
gi|157738619 smoothelin-like 1 [Homo sapiens] 55 3e-07
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 54 6e-07
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 53 1e-06
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 53 1e-06
>gi|212276096 leucine rich repeat (in FLII) interacting protein 1
isoform 3 [Homo sapiens]
Length = 808
Score = 1596 bits (4132), Expect = 0.0
Identities = 808/808 (100%), Positives = 808/808 (100%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR 60
MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR
Sbjct: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR 60
Query: 61 SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 120
SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS
Sbjct: 61 SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 120
Query: 121 GDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQ 180
GDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQ
Sbjct: 121 GDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQ 180
Query: 181 LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA 240
LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA
Sbjct: 181 LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA 240
Query: 241 LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRAS 300
LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRAS
Sbjct: 241 LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRAS 300
Query: 301 EVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLG 360
EVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLG
Sbjct: 301 EVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLG 360
Query: 361 TLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHT 420
TLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHT
Sbjct: 361 TLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHT 420
Query: 421 ENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQE 480
ENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQE
Sbjct: 421 ENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQE 480
Query: 481 AAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDT 540
AAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDT
Sbjct: 481 AAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDT 540
Query: 541 QNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNT 600
QNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNT
Sbjct: 541 QNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNT 600
Query: 601 DLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEG 660
DLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEG
Sbjct: 601 DLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEG 660
Query: 661 DDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKS 720
DDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKS
Sbjct: 661 DDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKS 720
Query: 721 EDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGRE 780
EDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGRE
Sbjct: 721 EDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGRE 780
Query: 781 PGHFNPESREDTRGGNEKGKSKEDCTMS 808
PGHFNPESREDTRGGNEKGKSKEDCTMS
Sbjct: 781 PGHFNPESREDTRGGNEKGKSKEDCTMS 808
>gi|212276070 leucine rich repeat (in FLII) interacting protein 1
isoform 4 [Homo sapiens]
Length = 784
Score = 1535 bits (3975), Expect = 0.0
Identities = 784/808 (97%), Positives = 784/808 (97%), Gaps = 24/808 (2%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR 60
MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR
Sbjct: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR 60
Query: 61 SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 120
SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS
Sbjct: 61 SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 120
Query: 121 GDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQ 180
GDTSISIDTEASIREIK DSLAEVEEKYKKAMVSNAQ
Sbjct: 121 GDTSISIDTEASIREIK------------------------DSLAEVEEKYKKAMVSNAQ 156
Query: 181 LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA 240
LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA
Sbjct: 157 LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA 216
Query: 241 LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRAS 300
LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRAS
Sbjct: 217 LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRAS 276
Query: 301 EVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLG 360
EVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLG
Sbjct: 277 EVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLG 336
Query: 361 TLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHT 420
TLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHT
Sbjct: 337 TLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHT 396
Query: 421 ENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQE 480
ENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQE
Sbjct: 397 ENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQE 456
Query: 481 AAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDT 540
AAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDT
Sbjct: 457 AAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDT 516
Query: 541 QNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNT 600
QNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNT
Sbjct: 517 QNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNT 576
Query: 601 DLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEG 660
DLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEG
Sbjct: 577 DLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEG 636
Query: 661 DDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKS 720
DDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKS
Sbjct: 637 DDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKS 696
Query: 721 EDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGRE 780
EDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGRE
Sbjct: 697 EDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGRE 756
Query: 781 PGHFNPESREDTRGGNEKGKSKEDCTMS 808
PGHFNPESREDTRGGNEKGKSKEDCTMS
Sbjct: 757 PGHFNPESREDTRGGNEKGKSKEDCTMS 784
>gi|212276104 leucine rich repeat (in FLII) interacting protein 1
isoform 5 [Homo sapiens]
Length = 752
Score = 1458 bits (3775), Expect = 0.0
Identities = 752/808 (93%), Positives = 752/808 (93%), Gaps = 56/808 (6%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR 60
MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE
Sbjct: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE--------- 51
Query: 61 SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 120
VEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS
Sbjct: 52 -----------------------VEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 88
Query: 121 GDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQ 180
GDTSISIDTEASIREIK DSLAEVEEKYKKAMVSNAQ
Sbjct: 89 GDTSISIDTEASIREIK------------------------DSLAEVEEKYKKAMVSNAQ 124
Query: 181 LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA 240
LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA
Sbjct: 125 LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA 184
Query: 241 LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRAS 300
LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRAS
Sbjct: 185 LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRAS 244
Query: 301 EVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLG 360
EVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLG
Sbjct: 245 EVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLG 304
Query: 361 TLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHT 420
TLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHT
Sbjct: 305 TLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHT 364
Query: 421 ENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQE 480
ENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQE
Sbjct: 365 ENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQE 424
Query: 481 AAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDT 540
AAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDT
Sbjct: 425 AAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDT 484
Query: 541 QNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNT 600
QNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNT
Sbjct: 485 QNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNT 544
Query: 601 DLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEG 660
DLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEG
Sbjct: 545 DLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEG 604
Query: 661 DDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKS 720
DDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKS
Sbjct: 605 DDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKS 664
Query: 721 EDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGRE 780
EDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGRE
Sbjct: 665 EDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGRE 724
Query: 781 PGHFNPESREDTRGGNEKGKSKEDCTMS 808
PGHFNPESREDTRGGNEKGKSKEDCTMS
Sbjct: 725 PGHFNPESREDTRGGNEKGKSKEDCTMS 752
>gi|212276088 leucine rich repeat (in FLII) interacting protein 1
isoform 2 [Homo sapiens]
Length = 394
Score = 433 bits (1114), Expect = e-121
Identities = 256/401 (63%), Positives = 276/401 (68%), Gaps = 68/401 (16%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR 60
MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE
Sbjct: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE--------- 51
Query: 61 SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 120
VEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS
Sbjct: 52 -----------------------VEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 88
Query: 121 GDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQ 180
GDTSISIDTEASIREIK DSLAEVEEKYKKAMVSNAQ
Sbjct: 89 GDTSISIDTEASIREIK------------------------DSLAEVEEKYKKAMVSNAQ 124
Query: 181 LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA 240
LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA
Sbjct: 125 LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA 184
Query: 241 LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLG--- 297
LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL
Sbjct: 185 LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRL 244
Query: 298 ------RASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKS 351
R +E ++ + +R+ + + + +D +++ D+ V + Q S
Sbjct: 245 KKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQIS 304
Query: 352 SEDTAPFLGTLAGATYEEQV---QSQILESSSLPENTVQVE 389
E+ V +SQ+ S EN ++E
Sbjct: 305 DLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIE 345
Score = 33.5 bits (75), Expect = 0.81
Identities = 38/159 (23%), Positives = 66/159 (41%), Gaps = 10/159 (6%)
Query: 461 PQELETSTGHSLEKEFTNQEAAE--PKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEV 518
P+ + + K EA E KE+ EV + E++ E G R+ +
Sbjct: 17 PEAQKLAEARLAAKRAARAEAREIRMKELERQQKEV-EERPEKDFTEKGSRNMPGLSAAT 75
Query: 519 PGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKK 578
S GT ++DT+ ++K+ E ++ +A+ S N + N+K
Sbjct: 76 LASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVS------NAQLDNEK 129
Query: 579 KKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRK 617
V+TLKD+ EL Q + S + EE+ K +R+
Sbjct: 130 TNFMYQVDTLKDMLLELEEQLAE-SRRQYEEKNKEFERE 167
>gi|212276078 leucine rich repeat (in FLII) interacting protein 1
isoform 1 [Homo sapiens]
Length = 640
Score = 332 bits (851), Expect = 8e-91
Identities = 195/293 (66%), Positives = 217/293 (74%), Gaps = 13/293 (4%)
Query: 47 RQQKEEDSERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAA 106
R+ S S S S+S R S +R S VEERPEKDFTEKGSRNMPGLSAA
Sbjct: 176 RRGSTSGSRAPSEYSGHLNSSSRASSRAS-SARASPVVEERPEKDFTEKGSRNMPGLSAA 234
Query: 107 TLASLGGTSSRRGSGDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAE 166
TLASLGGTSSRRGSGDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAE
Sbjct: 235 TLASLGGTSSRRGSGDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAE 294
Query: 167 VEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHA 226
VEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHA
Sbjct: 295 VEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHA 354
Query: 227 HSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQ----GPTKMTK 282
HSILQFQFAEVKEALKQREEMLE+ + + ++ E SD + ++ G + K
Sbjct: 355 HSILQFQFAEVKEALKQREEMLEEIRQLQQKQASSIREISDLQETIEWKDKKIGALERQK 414
Query: 283 EELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTE--KEQHTEDTVKD 333
E ++++S D R V +K E+ K I+ N+E T DT+ +
Sbjct: 415 EFFDSVRSERDDL--REEVVMLKEEL----KKHGIILNSEIATNGETSDTLNN 461
Score = 105 bits (261), Expect = 2e-22
Identities = 65/95 (68%), Positives = 68/95 (71%), Gaps = 23/95 (24%)
Query: 11 EIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE------------------- 51
E D L+ A++ AEARLAAKRAARAEAREIRMKELERQQKE
Sbjct: 22 EDDALNQIARE-AEARLAAKRAARAEAREIRMKELERQQKEIYQVQKKYYGLDTKWGDIE 80
Query: 52 ---EDSERYSRRSRRNTSASDEDERMSVGSRGSLR 83
EDSERYSRRSRRNTSASDEDERMSVGSRGSLR
Sbjct: 81 QWMEDSERYSRRSRRNTSASDEDERMSVGSRGSLR 115
Score = 34.3 bits (77), Expect = 0.47
Identities = 33/154 (21%), Positives = 63/154 (40%), Gaps = 4/154 (2%)
Query: 482 AEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQ 541
A + A ++ V + E++ E G R+ + S GT ++DT+
Sbjct: 199 ASSRASSARASPVVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTE 258
Query: 542 NEPLDMKEPDEEK---SDQQGEALDS-SQKKTKNKKKKNKKKKSPVPVETLKDVKKELTY 597
++KE +E K D +G+ + + K + + K KK+ V L + K Y
Sbjct: 259 ASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMY 318
Query: 598 QNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPK 631
Q L ++ E + + + + E +N+ E K
Sbjct: 319 QVDTLKDMLLELEEQLAESRRQYEEKNKEFEREK 352
>gi|197276647 leucine rich repeat (in FLII) interacting protein 2
isoform 3 [Homo sapiens]
Length = 424
Score = 253 bits (646), Expect = 5e-67
Identities = 164/394 (41%), Positives = 237/394 (60%), Gaps = 49/394 (12%)
Query: 9 SREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRNTSAS 68
S E + LS A++ AEARLAAKRAARAEAR+IRM+ELERQQKE D
Sbjct: 18 SAEDEALSNIARE-AEARLAAKRAARAEARDIRMRELERQQKELD--------------- 61
Query: 69 DEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISID 128
E+ +K + E +R SA+ L G SSRRGSGDTS ID
Sbjct: 62 -----------------EKSDKQYAENYTRPSSRNSASATTPLSGNSSRRGSGDTSSLID 104
Query: 129 TEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNF 188
+ S+ E++++ +LKDQIQDVEG+YMQGLKE+K+SL+EVEEKYKKAMVSNAQLDNEK N
Sbjct: 105 PDTSLSELRDIYDLKDQIQDVEGRYMQGLKELKESLSEVEEKYKKAMVSNAQLDNEKNNL 164
Query: 189 MYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEML 248
+YQVDTLKD++ E EEQ+AE R+ EEK+KE ER+KH S+LQ + E+KE L+QR+E++
Sbjct: 165 IYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERQKHMCSVLQHKMEELKEGLRQRDELI 224
Query: 249 EKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLG-RASEVE-VKN 306
EKHG+++ + NG+ S + T +++E L+S G+G L R ++ K
Sbjct: 225 EKHGLVIIPDGTPNGDVS---HEPVAGAITVVSQEAAQVLESAGEGPLDVRLRKLAGEKE 281
Query: 307 EIVANVGKREILHNTEKEQ--HTEDTVKDCVDIEVFPAGENTEDQK-SSEDTAPFLGTLA 363
E+++ + K ++ E+++ + TV D ++ + E Q+ ++ + + L+
Sbjct: 282 ELLSQIRKLKLQLEEERQKCSRNDGTVGDLAGLQNGSDLQFIEMQRDANRQISEYKFKLS 341
Query: 364 GA-----TYEEQV---QSQILESSSLPENTVQVE 389
A T E+ + + Q+L + EN +VE
Sbjct: 342 KAEQDITTLEQSISRLEGQVLRYKTAAENAEKVE 375
>gi|5453726 leucine rich repeat (in FLII) interacting protein 2
isoform 1 [Homo sapiens]
Length = 721
Score = 207 bits (526), Expect = 4e-53
Identities = 108/204 (52%), Positives = 150/204 (73%), Gaps = 3/204 (1%)
Query: 47 RQQKEEDSERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAA 106
R+ ++ +SR +RR + S+ D+ +S+ SL +E+ +K + E +R SA+
Sbjct: 258 RESVVSAADYFSRSNRRGSVVSEVDD-ISIPDLSSL--DEKSDKQYAENYTRPSSRNSAS 314
Query: 107 TLASLGGTSSRRGSGDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAE 166
L G SSRRGSGDTS ID + S+ E++++ +LKDQIQDVEG+YMQGLKE+K+SL+E
Sbjct: 315 ATTPLSGNSSRRGSGDTSSLIDPDTSLSELRDIYDLKDQIQDVEGRYMQGLKELKESLSE 374
Query: 167 VEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHA 226
VEEKYKKAMVSNAQLDNEK N +YQVDTLKD++ E EEQ+AE R+ EEK+KE ER+KH
Sbjct: 375 VEEKYKKAMVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERQKHM 434
Query: 227 HSILQFQFAEVKEALKQREEMLEK 250
S+LQ + E+KE L+QR+E++E+
Sbjct: 435 CSVLQHKMEELKEGLRQRDELIEE 458
Score = 62.8 bits (151), Expect = 1e-09
Identities = 46/96 (47%), Positives = 57/96 (59%), Gaps = 20/96 (20%)
Query: 9 SREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE----------------- 51
S E + LS A++ AEARLAAKRAARAEAR+IRM+ELERQQKE
Sbjct: 18 SAEDEALSNIARE-AEARLAAKRAARAEARDIRMRELERQQKEYSLHSFDRKWGQIQKWL 76
Query: 52 EDSE--RYSRRSRRNTSASDEDERMSVGSRGSLRVE 85
EDSE RYS RS + ++ +S+ S GS R +
Sbjct: 77 EDSERARYSHRSSHHRPYLGVEDALSIRSVGSHRYD 112
>gi|8923224 leucine rich repeat (in FLII) interacting protein 2
isoform 2 [Homo sapiens]
Length = 400
Score = 202 bits (514), Expect = 1e-51
Identities = 147/394 (37%), Positives = 214/394 (54%), Gaps = 73/394 (18%)
Query: 9 SREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRNTSAS 68
S E + LS A++ AEARLAAKRAARAEAR+IRM+ELERQQKE D
Sbjct: 18 SAEDEALSNIARE-AEARLAAKRAARAEARDIRMRELERQQKELD--------------- 61
Query: 69 DEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISID 128
E+ +K + E +R SA+ L G SSRRGSGDTS ID
Sbjct: 62 -----------------EKSDKQYAENYTRPSSRNSASATTPLSGNSSRRGSGDTSSLID 104
Query: 129 TEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNF 188
+ S+ E++E SL+EVEEKYKKAMVSNAQLDNEK N
Sbjct: 105 PDTSLSELRE------------------------SLSEVEEKYKKAMVSNAQLDNEKNNL 140
Query: 189 MYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEML 248
+YQVDTLKD++ E EEQ+AE R+ EEK+KE ER+KH S+LQ + E+KE L+QR+E++
Sbjct: 141 IYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERQKHMCSVLQHKMEELKEGLRQRDELI 200
Query: 249 EKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLG-RASEVE-VKN 306
EKHG+++ + NG+ S + T +++E L+S G+G L R ++ K
Sbjct: 201 EKHGLVIIPDGTPNGDVS---HEPVAGAITVVSQEAAQVLESAGEGPLDVRLRKLAGEKE 257
Query: 307 EIVANVGKREILHNTEKEQ--HTEDTVKDCVDIEVFPAGENTEDQK-SSEDTAPFLGTLA 363
E+++ + K ++ E+++ + TV D ++ + E Q+ ++ + + L+
Sbjct: 258 ELLSQIRKLKLQLEEERQKCSRNDGTVGDLAGLQNGSDLQFIEMQRDANRQISEYKFKLS 317
Query: 364 GA-----TYEEQV---QSQILESSSLPENTVQVE 389
A T E+ + + Q+L + EN +VE
Sbjct: 318 KAEQDITTLEQSISRLEGQVLRYKTAAENAEKVE 351
Score = 32.3 bits (72), Expect = 1.8
Identities = 42/183 (22%), Positives = 69/183 (37%), Gaps = 24/183 (13%)
Query: 510 DEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQN----EPLDMKEPDEEKSDQQGEALDSS 565
DEK K + N AT P + ++ + + +PD S+ + E+L
Sbjct: 61 DEKSDKQYAENYTRPSSRNSASATTPLSGNSSRRGSGDTSSLIDPDTSLSELR-ESLSEV 119
Query: 566 QKKTK-----NKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEE----------- 609
++K K N + N+K V+TLKDV +E Q + EE+
Sbjct: 120 EEKYKKAMVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERQKHMC 179
Query: 610 ---QVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTA 666
Q K + K + ++E+ E I + + N D P + QE V +
Sbjct: 180 SVLQHKMEELKEGLRQRDELIEKHGLVIIPDGTPNGDVSHEPVAGAITVVSQEAAQVLES 239
Query: 667 AEE 669
A E
Sbjct: 240 AGE 242
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 79.3 bits (194), Expect = 1e-14
Identities = 154/727 (21%), Positives = 278/727 (38%), Gaps = 156/727 (21%)
Query: 128 DTEASIREI---------------KELNELKDQIQDVEGKYMQGLKEMKDSLAEVE---- 168
DTEA+IR + K++ L+D++ + + + E+ D LA+++
Sbjct: 198 DTEAAIRALRKDIEEASLVKVELDKKVQSLQDEVAFLRSNHEE---EVADLLAQIQASHI 254
Query: 169 ----EKYKKAMVSNA------QLDNEKTNFMYQVDTLKDM----LLELEEQLAESRRQYE 214
+ Y K +S A QL++ M+Q + L E EQ E+ R +
Sbjct: 255 TVERKDYLKTDISTALKEIRSQLESHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIRSAK 314
Query: 215 EKNKEFEREKHAHSILQFQFAEVKEAL-KQREEMLEKHGIILNSEIATNGETSDTLNNVG 273
E+ E+ R+ + SI KE+L +Q ++ E+H L+S
Sbjct: 315 EEIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSS---------------- 358
Query: 274 YQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKD 333
YQ + + EL K E+ ++ + + L N VK
Sbjct: 359 YQDTIQQLENELRGTKW----------------EMARHLREYQDLLN----------VKM 392
Query: 334 CVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATY--------EEQVQSQILESSSLP--- 382
+DIE+ + E +++ T F G++ G Y ++Q +E+ L
Sbjct: 393 ALDIEIAAYRKLLEGEETRFST--FAGSITGPLYTHRPPITISSKIQKPKVEAPKLKVQH 450
Query: 383 --------ENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQ 434
E V+ E +E+ A T L S + E EA +V +
Sbjct: 451 KFVEEIIEETKVEDEKSEMEEALTAITEE-LAVSMKEEKKEAAEEKEEEPEAEEEEVAAK 509
Query: 435 AGTV-ASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTE 493
V A+ P ++ +++ E +E E + E+ + +E + KE E
Sbjct: 510 KSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKE--EGEQE 567
Query: 494 VGRDHNEEEGEETGLRDEKPI-------------------------KTEVPGSPAGTEGN 528
G E EGEE ++EK + K+ VP SP +G
Sbjct: 568 EGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGK 627
Query: 529 CQEATGPSTVDTQNEPLDMKEPDEEK--SDQQGEALDSSQKKTKNKKKKNKKKKSPVPVE 586
P V+ + + K P EEK S ++ K +K +K KSPVP
Sbjct: 628 SPVPKSP--VEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKS 685
Query: 587 TLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAES-------S 639
+++ K + + E +EE++VK ++ VE + E ++ +K AES +
Sbjct: 686 PVEEAKSKAEVGKGEQKE-EEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVA 744
Query: 640 ENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEG 699
E V ++ K+ L+ + +EG +Q E+ A G + G ++ +G
Sbjct: 745 EVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGG----------EGGSEEEGSDKGAKG 794
Query: 700 VAKDNAKIDGATQSSPAEPKSEDADRCTLPEHE----SPSQDISDACEAESTERCEMSEH 755
K++ ++G + E + E ++ + E E + D+S A E + ++ E
Sbjct: 795 SRKEDIAVNGEVEGK-EEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVV 853
Query: 756 PSQTVRK 762
++TV K
Sbjct: 854 VTKTVEK 860
Score = 39.3 bits (90), Expect = 0.015
Identities = 58/250 (23%), Positives = 104/250 (41%), Gaps = 28/250 (11%)
Query: 565 SQKKTKNKKKKNKKKKSPVPVETLKD---VKKELTYQNTDLSEIKEEEQVK-STDRKSAV 620
S K K K + K K VE + + V+ E + L+ I EE V ++K A
Sbjct: 433 SSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAA 492
Query: 621 EAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFE 680
E + E E ++++AA+ S P++K ++EG+ + +E + D
Sbjct: 493 EEKEEEPEAEEEEVAAKKSPVK--ATAPEVK-----EEEGEKEEEEGQEEEEEEDEGAKS 545
Query: 681 DDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISD 740
D + + G E +EG + +G T+ AE + E+A+ + E S++++
Sbjct: 546 DQAEEGGSEKEGSSEKEEGEQE-----EGETE---AEAEGEEAEAKEEKKVEEKSEEVAT 597
Query: 741 ACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFN-PESREDTRGGN--- 796
E + + E E V K+ ++ +P E G P+S + +G +
Sbjct: 598 KEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVP 657
Query: 797 -----EKGKS 801
EKGKS
Sbjct: 658 KSPVEEKGKS 667
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 68.2 bits (165), Expect = 3e-11
Identities = 106/490 (21%), Positives = 191/490 (38%), Gaps = 77/490 (15%)
Query: 331 VKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATY--------EEQVQSQILESSSLP 382
VK +DIE+ + E +++ T F G++ G Y ++Q +E+ L
Sbjct: 14 VKMALDIEIAAYRKLLEGEETRFST--FAGSITGPLYTHRPPITISSKIQKPKVEAPKLK 71
Query: 383 -----------ENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQV 431
E V+ E +E+ A T L S + E EA +V
Sbjct: 72 VQHKFVEEIIEETKVEDEKSEMEEALTAITEE-LAVSMKEEKKEAAEEKEEEPEAEEEEV 130
Query: 432 EEQAGTV-ASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAH 490
+ V A+ P ++ +++ E +E E + E+ + +E + KE
Sbjct: 131 AAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKE--EG 188
Query: 491 STEVGRDHNEEEGEETGLRDEKPI-------------------------KTEVPGSPAGT 525
E G E EGEE ++EK + K+ VP SP
Sbjct: 189 EQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEE 248
Query: 526 EGNCQEATGPSTVDTQNEPLDMKEPDEEK--SDQQGEALDSSQKKTKNKKKKNKKKKSPV 583
+G P V+ + + K P EEK S ++ K +K +K KSPV
Sbjct: 249 KGKSPVPKSP--VEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPV 306
Query: 584 PVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAES----- 638
P +++ K + + E +EE++VK ++ VE + E ++ +K AES
Sbjct: 307 PKSPVEEAKSKAEVGKGEQKE-EEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEE 365
Query: 639 --SENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEEL 696
+E V ++ K+ L+ + +EG +Q E+ A G + G ++
Sbjct: 366 AVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGG----------EGGSEEEGSDKG 415
Query: 697 DEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHE----SPSQDISDACEAESTERCEM 752
+G K++ ++G + E + E ++ + E E + D+S A E + ++ E
Sbjct: 416 AKGSRKEDIAVNGEVEGK-EEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEE 474
Query: 753 SEHPSQTVRK 762
++TV K
Sbjct: 475 KVVVTKTVEK 484
Score = 39.3 bits (90), Expect = 0.015
Identities = 58/250 (23%), Positives = 104/250 (41%), Gaps = 28/250 (11%)
Query: 565 SQKKTKNKKKKNKKKKSPVPVETLKD---VKKELTYQNTDLSEIKEEEQVK-STDRKSAV 620
S K K K + K K VE + + V+ E + L+ I EE V ++K A
Sbjct: 57 SSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAA 116
Query: 621 EAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFE 680
E + E E ++++AA+ S P++K ++EG+ + +E + D
Sbjct: 117 EEKEEEPEAEEEEVAAKKSPVK--ATAPEVK-----EEEGEKEEEEGQEEEEEEDEGAKS 169
Query: 681 DDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISD 740
D + + G E +EG + +G T+ AE + E+A+ + E S++++
Sbjct: 170 DQAEEGGSEKEGSSEKEEGEQE-----EGETE---AEAEGEEAEAKEEKKVEEKSEEVAT 221
Query: 741 ACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFN-PESREDTRGGN--- 796
E + + E E V K+ ++ +P E G P+S + +G +
Sbjct: 222 KEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVP 281
Query: 797 -----EKGKS 801
EKGKS
Sbjct: 282 KSPVEEKGKS 291
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 64.7 bits (156), Expect = 3e-10
Identities = 159/791 (20%), Positives = 290/791 (36%), Gaps = 128/791 (16%)
Query: 65 TSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTS 124
TS S++++ ++ R + +++ + E +R++ G +AA G S+
Sbjct: 93 TSRSEKEQLQALNDRFAGYIDKVRQ---LEAHNRSLEGEAAALRQQQAGRSAMG------ 143
Query: 125 ISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLD-- 182
E RE++E+ ++ G+ + + + +A V ++ + +
Sbjct: 144 -----ELYEREVREMRGAVLRLGAARGQLRLEQEHLLEDIAHVRQRLDDEARQREEAEAA 198
Query: 183 -NEKTNFMYQVDT----LKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQF--- 234
F + + L+ L+E+ RR ++E+ E + Q Q
Sbjct: 199 ARALARFAQEAEAARVDLQKKAQALQEECGYLRRHHQEEVGELLGQIQGSGAAQAQMQAE 258
Query: 235 ------AEVKEALKQREEMLEKHGI--ILNSE---------------IATNGETSDTLNN 271
+V AL++ LE H + L SE + T+ S
Sbjct: 259 TRDALKCDVTSALREIRAQLEGHAVQSTLQSEEWFRVRLDRLSEAAKVNTDAMRSAQEEI 318
Query: 272 VGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREI------LHNTEKEQ 325
Y+ + EL ALKST D + SE+E +++ + I L NT+ E
Sbjct: 319 TEYRRQLQARTTELEALKSTKDSLERQRSELEDRHQADIASYQEAIQQLDAELRNTKWEM 378
Query: 326 HTED-------TVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLA-GATYEEQVQSQILE 377
+ VK +DIE+ + E ++ P +L G V + I
Sbjct: 379 AAQLREYQDLLNVKMALDIEIAAYRKLLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKV 438
Query: 378 SSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGT 437
S V+ E + + T + TE V E + +E+ G
Sbjct: 439 KSEEKIKVVEKSEKETVIVEEQTEETQV--------------TEEVTEEEEKEAKEEEGK 484
Query: 438 VASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRD 497
G ++ ++ P E E ++ K +EA P E + E +
Sbjct: 485 EEE---GGEEEEAEGGEEETKSPPAE-EAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKS 540
Query: 498 HNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQ 557
E + E + + P K E P +EA P+ V K P++ KS
Sbjct: 541 PAEVKSPE---KAKSPAKEEAKSPPEAKSPEKEEAKSPAEV---------KSPEKAKSPA 588
Query: 558 QGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRK 617
+ EA ++ K+ K K K+++ P E VK+E +E+K E+ KS ++
Sbjct: 589 KEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEA----KSPAEVKSPEKAKSPTKE 644
Query: 618 SAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTL 677
EA++ +K A+S E P +K + K ++ A V A+ +
Sbjct: 645 ---EAKSPEKAKSPEKEEAKSPEKAKSP----VKAEAKSPEK------AKSPVKAEAKSP 691
Query: 678 DFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEH-ESPSQ 736
+ V+ A E + K+ AK SP + KS + PE +SP +
Sbjct: 692 EKAKSPVKE---EAKSPEKAKSPVKEEAK-------SPEKAKSPVKEEAKTPEKAKSPVK 741
Query: 737 DISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPG-REPGHFNPESREDTRGG 795
+ EA+S E+ + E K+ ++ + ++ +P + P +E+ +
Sbjct: 742 E-----EAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVK-S 795
Query: 796 NEKGKS--KED 804
EK KS KED
Sbjct: 796 PEKAKSPLKED 806
Score = 48.1 bits (113), Expect = 3e-05
Identities = 111/628 (17%), Positives = 233/628 (37%), Gaps = 84/628 (13%)
Query: 120 SGDTSISIDTEASIREIKE-------LNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYK 172
S T I + +E I+ +++ + E ++ Q E + KE K+ + EE +
Sbjct: 431 SVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGE 490
Query: 173 KAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQF 232
+ + + + K+ ++E E++ E K+ E E K
Sbjct: 491 EEEAEGGEEETKSPPAEEAASPEKEAKSPVKE---EAKSPAEAKSPEKEEAKSP------ 541
Query: 233 QFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTG 292
AEVK K + E+ + A + E + + + P K KS
Sbjct: 542 --AEVKSPEKAKSPAKEE---AKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPA 596
Query: 293 DGTLGRASEVEVKNEIVANVGKREILHNTEK--------EQHTEDTVKDCVDIEVFPAGE 344
+ ++ VK E + + + K E+ T ++ E + E
Sbjct: 597 EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE 656
Query: 345 NTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTP 404
E + + +P A A E+ +S + + PE E ++ ++P
Sbjct: 657 KEEAKSPEKAKSP---VKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSP--EKAKSP 711
Query: 405 LEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQEL 464
++ E A + V+E+A T ++ + E + L
Sbjct: 712 VKEE------------AKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTL 759
Query: 465 ETSTGHSLEKEFTNQEAAEPKEV---PAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGS 521
+ + + K +EA P + A S + E+ + D K + E+P
Sbjct: 760 DVKSPEA--KTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKK 817
Query: 522 PAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKS 581
+E P + + + + +KEP ++ +++ A +++K +KK++ KK++
Sbjct: 818 --------EEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEA 869
Query: 582 PVP-VETLKDVKKELTYQN---TDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAE 637
P P VE K+ E ++ E +++++V + ++++ + + + PK+K
Sbjct: 870 PKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVA 929
Query: 638 SSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELD 697
E P++ K K K ++ + AA E + DT + + +
Sbjct: 930 KKE----PDDAKAKEPSKPAEK----KEAAPE----------KKDTKEEKAKKPEEKPKT 971
Query: 698 EGVAKDNAKIDGATQSSPAEPKSEDADR 725
E AK++ D P++PK+E A++
Sbjct: 972 EAKAKED---DKTLSKEPSKPKAEKAEK 996
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 64.3 bits (155), Expect = 4e-10
Identities = 170/869 (19%), Positives = 329/869 (37%), Gaps = 115/869 (13%)
Query: 18 EAQKLAEARLAAKRAARAEAREIRMKELERQQKEED-----SERYSRRSRRNTSASDEDE 72
E + + +L A+ AEA E+R + ++Q+ E+ R RN +E +
Sbjct: 887 EEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKK 946
Query: 73 RMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEAS 132
+M +++ E+ E+G+R L T ++ + I + + +
Sbjct: 947 KMQA------HIQDLEEQLDEEEGARQKLQLEKVT------AEAKIKKMEEEILLLEDQN 994
Query: 133 IREIKELNELKDQIQDVEGKYMQGLKEMKD----------SLAEVEEKYKKAMVSNAQLD 182
+ IKE ++D+I + + + ++ K+ ++++EE+ KK + +L+
Sbjct: 995 SKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELE 1054
Query: 183 NEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFE-----------REKHAHSI-- 229
K + L+D + EL+ Q+ E + Q +K +E + + +A +
Sbjct: 1055 KAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVR 1114
Query: 230 -LQFQFAEVK---EALKQREEMLEKHGIILNSEI-ATNGETSDTLNNVGYQGPTKMTKEE 284
LQ Q AE++ E+ K EK L+ E+ A E DTL+ T ++E
Sbjct: 1115 ELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLD-------TTAAQQE 1167
Query: 285 LNALKSTGDGTLGRASEVEVKNE--IVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPA 342
L + L +A E E KN + ++ +R E + E + ++E
Sbjct: 1168 LRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQ 1227
Query: 343 GENTEDQKSSEDTAPFLGTLAGATYEEQ---VQSQILESSSLPENTVQVESNEVMGAPD- 398
G T++++ + + A + ++ + Q Q L + + ++VE E
Sbjct: 1228 GLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQN 1287
Query: 399 --DRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKC 456
D T LE + + + TQ Q T L S ++K
Sbjct: 1288 ELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLS-SRIRQLEEEKN 1346
Query: 457 MVEVPQELETSTGHSLEKE---FTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKP 513
++ QE E +LEK+ +Q A K+V ++G + EE ++ L+D +
Sbjct: 1347 SLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV---DDDLGTIESLEEAKKKLLKDAEA 1403
Query: 514 IKTEVPGSPAG------TEGNCQEATGPSTVDTQNE-----PLDMKEPD------EEKSD 556
+ + T+ Q+ TVD ++ L+ K+ EEKS
Sbjct: 1404 LSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSI 1463
Query: 557 QQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTD- 615
A + + + + ++K+ K +E + K+E QN L E+ D
Sbjct: 1464 SARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDV 1523
Query: 616 ---------RKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTA 666
K A+E Q E +++ E D ++ + Q D+QT
Sbjct: 1524 GKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTR 1583
Query: 667 AEEVLADGDTL---------DFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAE 717
E+ L + ED+ Q + A ++++ + A+I+ A
Sbjct: 1584 DEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAAN------ 1637
Query: 718 PKSEDADRCTLPEHESPSQDISDACEAESTERCEM--SEHPSQTVRKALDSNSLE-NDDL 774
K+ D L + ++ +D E R E+ S+ K+L++ L+ ++L
Sbjct: 1638 -KARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEEL 1696
Query: 775 SAPGREPGHFNPESRE--DTRGGNEKGKS 801
++ R H E E D + GKS
Sbjct: 1697 ASSERARRHAEQERDELADEITNSASGKS 1725
Score = 43.1 bits (100), Expect = 0.001
Identities = 164/849 (19%), Positives = 316/849 (37%), Gaps = 106/849 (12%)
Query: 9 SREIDCLSPEAQKLAEARLAAKRAARAEAREIR--MKELERQQKEEDSERYSRRSRRNTS 66
S E++ L E + + A + +E+ K LE + K +++ R R T+
Sbjct: 1145 SEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATA 1204
Query: 67 ASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSIS 126
+ E++ R +E+ K E ++ + A + L + +
Sbjct: 1205 LEELSEQLEQAKRFKANLEKN--KQGLETDNKEL----ACEVKVLQQVKAESEHKRKKLD 1258
Query: 127 IDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNE-- 184
+ ++ E + L+ ++ + K L + L E E+K K A L+++
Sbjct: 1259 AQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQ 1318
Query: 185 KTNFMYQVDT-----LKDMLLELEEQ---LAESRRQYEEKNKEFEREKHAHSILQFQFAE 236
T + Q +T L + +LEE+ L E + + EE K E++ A LQ Q A+
Sbjct: 1319 DTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLA---LQSQLAD 1375
Query: 237 VK----------EALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELN 286
K E+L++ ++ L K L+ + D L ++EL+
Sbjct: 1376 TKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKT-----KNRLQQELD 1430
Query: 287 ALKSTGDGTLGRASEVEVK----NEIVA---NVGKR--EILHNTEKEQHTEDT------- 330
L D AS +E K ++++A ++ R E E E ++T
Sbjct: 1431 DLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLAR 1490
Query: 331 -VKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVE 389
+++ ++ + +N + + ED + +E + + LE + E Q+E
Sbjct: 1491 ALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALE-QQVEEMRTQLE 1549
Query: 390 --SNEVMGAPDDRTRTPLEPSNCWSDLDGGNHT-----ENVGEAAVTQVEE--------- 433
+E+ D + R + + + T E + QV E
Sbjct: 1550 ELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDER 1609
Query: 434 --QAGTVAS-----CPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEA-AEPK 485
+A VAS L + + +K EV ++L + + +EA A
Sbjct: 1610 KQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRD 1669
Query: 486 EVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPL 545
E+ A S E + E E L++E +E A E + ++ ++ L
Sbjct: 1670 EIFAQSKESEKKLKSLEAEILQLQEEL-ASSERARRHAEQERDELADEITNSASGKSALL 1728
Query: 546 DMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEI 605
D K E + Q E L+ Q + + ++ +K+ + V+TL N +L+
Sbjct: 1729 DEKRRLEARIAQLEEELEEEQ--SNMELLNDRFRKTTLQVDTL----------NAELAAE 1776
Query: 606 KEEEQVKSTDRKSAVEAQNEVTENPKQK----IAAESSENVDCPENPKIKLDGKLDQEGD 661
+ Q KS + + +E QN+ + Q+ + ++ + E +L+ +L+QE
Sbjct: 1777 RSAAQ-KSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAK 1835
Query: 662 DVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSE 721
+ AA L ++ +Q R ++ E + K NA++ + E E
Sbjct: 1836 --ERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQ--LEEAEE 1891
Query: 722 DADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREP 781
+A R + +++ DA EA E+S T++ L + S GR
Sbjct: 1892 EATRANASRRKL-QRELDDATEANEGLSREVS-----TLKNRLRRGGPISFSSSRSGRRQ 1945
Query: 782 GHFNPESRE 790
H S E
Sbjct: 1946 LHLEGASLE 1954
Score = 35.0 bits (79), Expect = 0.28
Identities = 94/492 (19%), Positives = 187/492 (38%), Gaps = 51/492 (10%)
Query: 134 REIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVD 193
R ++E E K++ + + ++++ S +V + + S L+ + Q++
Sbjct: 1490 RALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLE 1549
Query: 194 TLKDML-------LELEEQLAESRRQYE---EKNKEFEREKHAHSILQFQ--FAEVKEAL 241
L+D L L LE + + Q+E + E EK I Q + AE+++
Sbjct: 1550 ELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDER 1609
Query: 242 KQR------EEMLEKHGIILNSEI-ATNGETSDTLNNV-GYQGPTKMTKEELNALKSTGD 293
KQR ++ +E L ++I A N + + + Q K + EL +++ D
Sbjct: 1610 KQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRD 1669
Query: 294 GTLGRASEVEVK-NEIVANV--GKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQK 350
++ E E K + A + + E+ + +H E + D A +
Sbjct: 1670 EIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLD 1729
Query: 351 SSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVES-NEVMGA------PDDRTRT 403
+ L EEQ ++L + + T+QV++ N + A D R
Sbjct: 1730 EKRRLEARIAQLEEELEEEQSNMELL-NDRFRKTTLQVDTLNAELAAERSAAQKSDNARQ 1788
Query: 404 PLEPSN-----CWSDLDGG-----NHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHD 453
LE N +L+G T + EA + Q+EEQ A ++ V
Sbjct: 1789 QLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAK-ERAAANKLVRRT 1847
Query: 454 DKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLR-DEK 512
+K + E+ ++E E+ +Q + ++ A ++ R E E E T +
Sbjct: 1848 EKKLKEIFMQVED------ERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRR 1901
Query: 513 PIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDM--KEPDEEKSDQQGEALDSSQKKTK 570
++ E+ + EG +E + + P+ + +G +L+ S T+
Sbjct: 1902 KLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDDDTE 1961
Query: 571 NKKKKNKKKKSP 582
+K + + P
Sbjct: 1962 SKTSDVNETQPP 1973
Score = 33.1 bits (74), Expect = 1.1
Identities = 54/269 (20%), Positives = 113/269 (42%), Gaps = 34/269 (12%)
Query: 5 AAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSE-RYSRRSRR 63
A+ + EID K EA++ A AR E + ++++L+ Q K+ E +R SR
Sbjct: 1617 ASKKKMEIDL------KDLEAQIEAANKARDEVIK-QLRKLQAQMKDYQRELEEARASRD 1669
Query: 64 NTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDT 123
A ++ + S + ++ + E +E+ R+ + L + SG +
Sbjct: 1670 EIFAQSKESEKKLKSLEAEILQLQEELASSERARRH----AEQERDELADEITNSASGKS 1725
Query: 124 SISIDT---EASIREIKE-LNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSN- 178
++ + EA I +++E L E + ++ + ++ + ++ AE+ + A S+
Sbjct: 1726 ALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDN 1785
Query: 179 --AQLDNE---------------KTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFE 221
QL+ + K+ F + L+ + +LEEQL + ++ NK
Sbjct: 1786 ARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVR 1845
Query: 222 REKHAHSILQFQFAEVKEALKQREEMLEK 250
R + + Q + + Q +E +EK
Sbjct: 1846 RTEKKLKEIFMQVEDERRHADQYKEQMEK 1874
Score = 32.0 bits (71), Expect = 2.4
Identities = 57/260 (21%), Positives = 115/260 (44%), Gaps = 30/260 (11%)
Query: 8 QSREIDCLSPEAQKLAEARLAAKR-AARAEAREIRMKEL-------ERQQKEEDSERYSR 59
+ ++ D L E +K AR A +R A AEARE K L E + +E+ ER ++
Sbjct: 1449 KQKKFDQLLAE-EKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNK 1507
Query: 60 RSRRN-----TSASDEDERMSVGSRGSLRVEERPEKDFT--EKGSRNMPGLSAATLASLG 112
+ R + +S D + + + +E++ E+ T E+ + A L
Sbjct: 1508 QLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEV 1567
Query: 113 GTSSRRGSGDTSISIDTEASIRE----IKELNELKDQIQDVEGKYMQGL---KEMKDSLA 165
+ + + + E + + IK++ EL+ +++D + + K+M+ L
Sbjct: 1568 NMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLK 1627
Query: 166 EVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKH 225
++E + + A + ++ + Q +KD ELEE A SR + ++KE E++
Sbjct: 1628 DLEAQIEAANKARDEVIKQLRKLQAQ---MKDYQRELEEARA-SRDEIFAQSKESEKKLK 1683
Query: 226 AHSILQFQFAEVKEALKQRE 245
+ L+ + +++E L E
Sbjct: 1684 S---LEAEILQLQEELASSE 1700
Score = 31.2 bits (69), Expect = 4.0
Identities = 42/206 (20%), Positives = 78/206 (37%), Gaps = 25/206 (12%)
Query: 545 LDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSE 604
L + +EE + E L +K+TK + + + ++ + K++ E T+L
Sbjct: 845 LQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFA 904
Query: 605 IKEEEQVKSTDRKSAV--------------EAQNEVTENPKQKIAA---ESSENVDCPEN 647
EE + + +K + E +N++ +N K+K+ A + E +D E
Sbjct: 905 EAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEG 964
Query: 648 PKIKLDGKLDQEGDDVQTAAEEVLADGDTLD--------FEDDTVQSSGPRAGGEELDEG 699
+ KL + ++ EE+L D ED + S A EE +
Sbjct: 965 ARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKN 1024
Query: 700 VAKDNAKIDGATQSSPAEPKSEDADR 725
+AK K + K E+ R
Sbjct: 1025 LAKIRNKQEVMISDLEERLKKEEKTR 1050
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 64.3 bits (155), Expect = 4e-10
Identities = 139/713 (19%), Positives = 279/713 (39%), Gaps = 89/713 (12%)
Query: 18 EAQKLAEARLAAKRAARAEAR-EIRMKEL-ERQQKEEDSERYSRRSRRNTSASDEDERMS 75
EA+ LA+A + + + + E ++KE+ ER + EE+ +R + +
Sbjct: 900 EAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKD 959
Query: 76 VGSRGSLRVEERPEKDFTEKGSRN----MPGLSAATLASLGGTSSRRGSGDTSISIDTEA 131
+ + EK TE +N M GL T+A L D +A
Sbjct: 960 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE-TIAKLTKEKKALQEAHQQTLDDLQA 1018
Query: 132 SIREIKELNE----LKDQIQDVEGKYMQGLK---EMKDSLAEVEEKYKKAMVSNAQLDNE 184
++ L + L+ Q+ D+EG Q K +++ + ++E K A S ++NE
Sbjct: 1019 EEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENE 1078
Query: 185 K--------------TNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSIL 230
K +N +++ + + ++L++++ E + + EE +E E E+ + +
Sbjct: 1079 KQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKA 1138
Query: 231 QFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKS 290
+ Q +++ L++ E LE+ G +++I N + + + EE
Sbjct: 1139 EKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKM------RRDLEEATLQHE 1192
Query: 291 TGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTED-Q 349
TL + + VA +G++ + N ++ + + K + +E+ N E
Sbjct: 1193 ATAATLRKKHA-----DSVAELGEQ--IDNLQRVKQKLEKEKSEMKMEIDDLASNVETVS 1245
Query: 350 KSSEDTAPFLGTLAGATYE----EQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPL 405
K+ + TL E E+ Q +++ + +Q ES E D++
Sbjct: 1246 KAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALV- 1304
Query: 406 EPSNCWSDLDGGNH--TENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCM---VEV 460
S L G T+ + E Q+EE+ A L H+ + HD + E
Sbjct: 1305 ------SQLSRGKQAFTQQIEELK-RQLEEEIK--AKNALAHALQSSRHDCDLLREQYEE 1355
Query: 461 PQELETSTGHSLEKEFTN----------------QEAAEPKEVPAHSTEVGRDHNEEEGE 504
QE + +L K T +E E K+ A + +H E
Sbjct: 1356 EQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNA 1415
Query: 505 ETGL--RDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPD-EEKSDQQGEA 561
+ + ++ ++ EV E + + +D + D + ++K ++
Sbjct: 1416 KCASLEKTKQRLQNEVEDLMLDVE---RTNAACAALDKKQRNFDKILAEWKQKCEETHAE 1472
Query: 562 LDSSQKKTKNK-----KKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDR 616
L++SQK+ ++ K KN ++S +ETLK K L + +DL+E + E K
Sbjct: 1473 LEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTE-QIAEGGKRIHE 1531
Query: 617 KSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEE 669
++ Q E + Q E+ +++ E +++ +L+Q +V E
Sbjct: 1532 LEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1584
Score = 43.5 bits (101), Expect = 8e-04
Identities = 71/336 (21%), Positives = 141/336 (41%), Gaps = 34/336 (10%)
Query: 7 AQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRNTS 66
A +++I+ L + ++ +A+ A A ++ + +L R+Q EE+ E + R +
Sbjct: 1313 AFTQQIEELKRQLEEEIKAKNALAHALQSSRHDC---DLLREQYEEEQESKAELQRALSK 1369
Query: 67 ASDE--DERMSVGSRGSLRVEERPE--KDFTEKGSRNMPGLSA--ATLASLGGTSSRRGS 120
A+ E R + R EE E K ++ + A A ASL T R +
Sbjct: 1370 ANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQN 1429
Query: 121 GDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQ 180
+ +D E + L++ + + ++ Q +E AE+E K+A +
Sbjct: 1430 EVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETH---AELEASQKEARSLGTE 1486
Query: 181 LDNEKTNF---MYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEV 237
L K + + Q++TLK L++++++ Q E K + ++ + E+
Sbjct: 1487 LFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCEL 1546
Query: 238 KEALKQREEMLE-KHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALK------- 289
+ AL++ E LE + G IL ++ N S+ + + EE++ LK
Sbjct: 1547 QAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK------DEEIDQLKRNHIRIV 1600
Query: 290 ----STGDGTL-GRASEVEVKNEIVANVGKREILHN 320
ST D + R + +K ++ ++ + EI N
Sbjct: 1601 ESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLN 1636
Score = 33.9 bits (76), Expect = 0.62
Identities = 43/229 (18%), Positives = 91/229 (39%), Gaps = 54/229 (23%)
Query: 22 LAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRNTSASDEDERMSVGSRGS 81
L EAR A ++A +A M E +KE+D+ + R ++N + +D +
Sbjct: 1751 LQEARNAEEKAKKAITDAAMMAE--ELKKEQDTSAHLERMKKNMEQTVKDLQ-------- 1800
Query: 82 LRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKELNE 141
LR++E A LA GG K++ +
Sbjct: 1801 LRLDE------------------AEQLALKGGK----------------------KQIQK 1820
Query: 142 LKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLE 201
L+ +++++EG+ K +++ + + ++ Q + ++ N + L+D++ +
Sbjct: 1821 LEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNIL----RLQDLVDK 1876
Query: 202 LEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEK 250
L+ ++ +RQ EE ++ LQ + E +E E + K
Sbjct: 1877 LQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNK 1925
Score = 32.0 bits (71), Expect = 2.4
Identities = 106/592 (17%), Positives = 226/592 (38%), Gaps = 73/592 (12%)
Query: 125 ISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNE 184
+ + +A + + E DQ+ + + +KE+ + + EE + +L++E
Sbjct: 893 LQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 952
Query: 185 KTNFMYQVDTLKDMLLELEEQ----------LAESRRQYEEKNKEFEREKHAHSILQFQF 234
+ +D L+ L ++E++ L E +E + +EK A LQ
Sbjct: 953 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKA---LQEAH 1009
Query: 235 AEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDG 294
+ + L+ E +K + ++I + D ++ + +M E K GD
Sbjct: 1010 QQTLDDLQAEE---DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKR-KLEGDL 1065
Query: 295 TLGRASEVEVKNE---IVANVGKRE-----ILHNTEKEQ----HTEDTVKDCVDIEVFPA 342
L + S ++++NE + + K+E + E EQ + +K+ + +
Sbjct: 1066 KLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKE-LQARIEEL 1124
Query: 343 GENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTR 402
E E +++S A + EE + ++ E+ + Q+E N+ A + R
Sbjct: 1125 EEEIEAERASRAKAEKQRSDLSRELEE-ISERLEEAGG--ATSAQIEMNKKREAEFQKMR 1181
Query: 403 TPLEPSNCWSDLDGG----NHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMV 458
LE + + H ++V E Q++ S+ + DD +
Sbjct: 1182 RDLEEATLQHEATAATLRKKHADSVAELG-EQIDNLQRVKQKLEKEKSEMKMEIDD---L 1237
Query: 459 EVPQELETSTGHSLEK----------EFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGL 508
E + +LEK E ++E + + + + + GR E GE +
Sbjct: 1238 ASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGR-LQTESGEFSRQ 1296
Query: 509 RDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKS-DQQGEALDSSQK 567
DEK Q + G Q E L + +E K+ + AL SS+
Sbjct: 1297 LDEKEALVS------------QLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRH 1344
Query: 568 KTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAV-EAQNEV 626
+++ ++++ E+ ++++ L+ NT++++ + + + + R + EA+ ++
Sbjct: 1345 DCDLLREQYEEEQ-----ESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKL 1399
Query: 627 TENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLD 678
+ + + N C K K +L E +D+ E A LD
Sbjct: 1400 AQRLQAAEEHVEAVNAKCASLEKTK--QRLQNEVEDLMLDVERTNAACAALD 1449
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 64.3 bits (155), Expect = 4e-10
Identities = 139/713 (19%), Positives = 279/713 (39%), Gaps = 89/713 (12%)
Query: 18 EAQKLAEARLAAKRAARAEAR-EIRMKEL-ERQQKEEDSERYSRRSRRNTSASDEDERMS 75
EA+ LA+A + + + + E ++KE+ ER + EE+ +R + +
Sbjct: 900 EAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKD 959
Query: 76 VGSRGSLRVEERPEKDFTEKGSRN----MPGLSAATLASLGGTSSRRGSGDTSISIDTEA 131
+ + EK TE +N M GL T+A L D +A
Sbjct: 960 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE-TIAKLTKEKKALQEAHQQTLDDLQA 1018
Query: 132 SIREIKELNE----LKDQIQDVEGKYMQGLK---EMKDSLAEVEEKYKKAMVSNAQLDNE 184
++ L + L+ Q+ D+EG Q K +++ + ++E K A S ++NE
Sbjct: 1019 EEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENE 1078
Query: 185 K--------------TNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSIL 230
K +N +++ + + ++L++++ E + + EE +E E E+ + +
Sbjct: 1079 KQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKA 1138
Query: 231 QFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKS 290
+ Q +++ L++ E LE+ G +++I N + + + EE
Sbjct: 1139 EKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKM------RRDLEEATLQHE 1192
Query: 291 TGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTED-Q 349
TL + + VA +G++ + N ++ + + K + +E+ N E
Sbjct: 1193 ATAATLRKKHA-----DSVAELGEQ--IDNLQRVKQKLEKEKSEMKMEIDDLASNVETVS 1245
Query: 350 KSSEDTAPFLGTLAGATYE----EQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPL 405
K+ + TL E E+ Q +++ + +Q ES E D++
Sbjct: 1246 KAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALV- 1304
Query: 406 EPSNCWSDLDGGNH--TENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCM---VEV 460
S L G T+ + E Q+EE+ A L H+ + HD + E
Sbjct: 1305 ------SQLSRGKQAFTQQIEELK-RQLEEEIK--AKNALAHALQSSRHDCDLLREQYEE 1355
Query: 461 PQELETSTGHSLEKEFTN----------------QEAAEPKEVPAHSTEVGRDHNEEEGE 504
QE + +L K T +E E K+ A + +H E
Sbjct: 1356 EQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNA 1415
Query: 505 ETGL--RDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPD-EEKSDQQGEA 561
+ + ++ ++ EV E + + +D + D + ++K ++
Sbjct: 1416 KCASLEKTKQRLQNEVEDLMLDVE---RTNAACAALDKKQRNFDKILAEWKQKCEETHAE 1472
Query: 562 LDSSQKKTKNK-----KKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDR 616
L++SQK+ ++ K KN ++S +ETLK K L + +DL+E + E K
Sbjct: 1473 LEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTE-QIAEGGKRIHE 1531
Query: 617 KSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEE 669
++ Q E + Q E+ +++ E +++ +L+Q +V E
Sbjct: 1532 LEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1584
Score = 43.5 bits (101), Expect = 8e-04
Identities = 71/336 (21%), Positives = 141/336 (41%), Gaps = 34/336 (10%)
Query: 7 AQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRNTS 66
A +++I+ L + ++ +A+ A A ++ + +L R+Q EE+ E + R +
Sbjct: 1313 AFTQQIEELKRQLEEEIKAKNALAHALQSSRHDC---DLLREQYEEEQESKAELQRALSK 1369
Query: 67 ASDE--DERMSVGSRGSLRVEERPE--KDFTEKGSRNMPGLSA--ATLASLGGTSSRRGS 120
A+ E R + R EE E K ++ + A A ASL T R +
Sbjct: 1370 ANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQN 1429
Query: 121 GDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQ 180
+ +D E + L++ + + ++ Q +E AE+E K+A +
Sbjct: 1430 EVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETH---AELEASQKEARSLGTE 1486
Query: 181 LDNEKTNF---MYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEV 237
L K + + Q++TLK L++++++ Q E K + ++ + E+
Sbjct: 1487 LFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCEL 1546
Query: 238 KEALKQREEMLE-KHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALK------- 289
+ AL++ E LE + G IL ++ N S+ + + EE++ LK
Sbjct: 1547 QAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK------DEEIDQLKRNHIRIV 1600
Query: 290 ----STGDGTL-GRASEVEVKNEIVANVGKREILHN 320
ST D + R + +K ++ ++ + EI N
Sbjct: 1601 ESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLN 1636
Score = 33.9 bits (76), Expect = 0.62
Identities = 43/229 (18%), Positives = 91/229 (39%), Gaps = 54/229 (23%)
Query: 22 LAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRNTSASDEDERMSVGSRGS 81
L EAR A ++A +A M E +KE+D+ + R ++N + +D +
Sbjct: 1751 LQEARNAEEKAKKAITDAAMMAE--ELKKEQDTSAHLERMKKNMEQTVKDLQ-------- 1800
Query: 82 LRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKELNE 141
LR++E A LA GG K++ +
Sbjct: 1801 LRLDE------------------AEQLALKGGK----------------------KQIQK 1820
Query: 142 LKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLE 201
L+ +++++EG+ K +++ + + ++ Q + ++ N + L+D++ +
Sbjct: 1821 LEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNIL----RLQDLVDK 1876
Query: 202 LEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEK 250
L+ ++ +RQ EE ++ LQ + E +E E + K
Sbjct: 1877 LQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNK 1925
Score = 32.0 bits (71), Expect = 2.4
Identities = 106/592 (17%), Positives = 226/592 (38%), Gaps = 73/592 (12%)
Query: 125 ISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNE 184
+ + +A + + E DQ+ + + +KE+ + + EE + +L++E
Sbjct: 893 LQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 952
Query: 185 KTNFMYQVDTLKDMLLELEEQ----------LAESRRQYEEKNKEFEREKHAHSILQFQF 234
+ +D L+ L ++E++ L E +E + +EK A LQ
Sbjct: 953 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKA---LQEAH 1009
Query: 235 AEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDG 294
+ + L+ E +K + ++I + D ++ + +M E K GD
Sbjct: 1010 QQTLDDLQAEE---DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKR-KLEGDL 1065
Query: 295 TLGRASEVEVKNE---IVANVGKRE-----ILHNTEKEQ----HTEDTVKDCVDIEVFPA 342
L + S ++++NE + + K+E + E EQ + +K+ + +
Sbjct: 1066 KLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKE-LQARIEEL 1124
Query: 343 GENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTR 402
E E +++S A + EE + ++ E+ + Q+E N+ A + R
Sbjct: 1125 EEEIEAERASRAKAEKQRSDLSRELEE-ISERLEEAGG--ATSAQIEMNKKREAEFQKMR 1181
Query: 403 TPLEPSNCWSDLDGG----NHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMV 458
LE + + H ++V E Q++ S+ + DD +
Sbjct: 1182 RDLEEATLQHEATAATLRKKHADSVAELG-EQIDNLQRVKQKLEKEKSEMKMEIDD---L 1237
Query: 459 EVPQELETSTGHSLEK----------EFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGL 508
E + +LEK E ++E + + + + + GR E GE +
Sbjct: 1238 ASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGR-LQTESGEFSRQ 1296
Query: 509 RDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKS-DQQGEALDSSQK 567
DEK Q + G Q E L + +E K+ + AL SS+
Sbjct: 1297 LDEKEALVS------------QLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRH 1344
Query: 568 KTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAV-EAQNEV 626
+++ ++++ E+ ++++ L+ NT++++ + + + + R + EA+ ++
Sbjct: 1345 DCDLLREQYEEEQ-----ESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKL 1399
Query: 627 TENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLD 678
+ + + N C K K +L E +D+ E A LD
Sbjct: 1400 AQRLQAAEEHVEAVNAKCASLEKTK--QRLQNEVEDLMLDVERTNAACAALD 1449
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 61.6 bits (148), Expect = 3e-09
Identities = 155/725 (21%), Positives = 293/725 (40%), Gaps = 97/725 (13%)
Query: 1 MTSPAAAQSRE-IDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSR 59
M AQ R I ++ + ++L E + ++RAA E K L QK E++ R +
Sbjct: 379 MKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELE----KALSTAQKTEEARRKLK 434
Query: 60 RSR----RNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTS 115
+ + E+ER+S+ S RV++ D +K S A L L
Sbjct: 435 AEMDEQIKTIEKTSEEERISLQQELS-RVKQEVV-DVMKKSSEEQ----IAKLQKLHEKE 488
Query: 116 SRRGSGDTSISIDTEASIREIKELNELKDQIQDVEGKYMQ--GLKEMKDSLAEVE-EKYK 172
R + + + T RE +E ++K ++ + +Y++ KE ++SLA E E K
Sbjct: 489 LARKEQELTKKLQTRE--REFQE--QMKVALEKSQSEYLKISQEKEQQESLALEELELQK 544
Query: 173 KAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEF----EREKHAHS 228
KA+++ ++ N+ + + +T + +LELE L +S ++ + ++K+ E EK+ H+
Sbjct: 545 KAILTESE--NKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHN 602
Query: 229 ILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNAL 288
K+ M+EKH +E+ + D L Q + + E+ L
Sbjct: 603 -------------KEITVMVEKH----KTELESLKHQQDALWTEKLQVLKQQYQTEMEKL 645
Query: 289 KSTGDGTLGRASEVEVKN-EIVANVGKREILHNTEKEQHTEDTVKDCVDIE---VFPAGE 344
+ + + E +K+ EI+ E+ T ++ + T + + E V A
Sbjct: 646 REKCE----QEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARH 701
Query: 345 NTEDQKS--SEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTR 402
E++ S + T L E++ Q S + E+ V ++ E D +
Sbjct: 702 KLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTE-KALKDQINQ 760
Query: 403 TPLEPSNCWSDL-DGGNHTENV------GEAAVTQVEEQAGTVASCPLGHSDDTVYHDDK 455
L L + H EN+ E + Q + S + T ++++
Sbjct: 761 LELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQ 820
Query: 456 CMVEVPQELETSTGHSLEKEFTNQEAAEPKEV----PAHSTEVGRDHNEEEGEETGLRDE 511
+ L+ T L + + A+ K+V AH +V + E + + + +
Sbjct: 821 LAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQK 880
Query: 512 KPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQK---- 567
T+V S QE T V+ +N L M+E +++ + + L + +
Sbjct: 881 VKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHI 940
Query: 568 ---------KTKNKKKKNKKKKSPVPVETLK--------DVKKELTYQNTDLSEIKEEEQ 610
K + KK + K+K+ ETLK +KKEL +LS+ +++
Sbjct: 941 LNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFN 1000
Query: 611 VKSTDRKSA-----VEAQNEVTENPKQKIAAESSENVDCPE-NPKIKL-DGKLDQEGDDV 663
K + A +A + + N K++I ES V E N I + + KL+Q+ +++
Sbjct: 1001 AKMLEMAQANSAGISDAVSRLETNQKEQI--ESLTEVHRRELNDVISIWEKKLNQQAEEL 1058
Query: 664 QTAAE 668
Q E
Sbjct: 1059 QEIHE 1063
Score = 42.4 bits (98), Expect = 0.002
Identities = 98/543 (18%), Positives = 216/543 (39%), Gaps = 63/543 (11%)
Query: 146 IQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDML-LELEE 204
I+++ K ++ L + L + + + + + +L+ E + Q D +K L +++E
Sbjct: 668 IEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDE 727
Query: 205 QLAESRRQYEEKNKEFERE-KHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNG 263
Q ++Q + KE E + L+ Q +++ LK+R++ L++H + + A
Sbjct: 728 QKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIK 787
Query: 264 ETSDTLNNVG-----YQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREIL 318
+ L +Q T E+ A + + ++E + ++ +
Sbjct: 788 RSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQ-----V 842
Query: 319 HNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQS--QIL 376
E ++ T D I+V + E Q S E++V+S Q+
Sbjct: 843 AEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSE--------------MEQKVKSLTQVY 888
Query: 377 ESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAG 436
ES N Q ++ +++ +E N + G E +E +
Sbjct: 889 ESKLEDGNKEQEQTKQIL----------VEKENMILQMREGQKKEIEILTQKLSAKEDSI 938
Query: 437 TVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGR 496
+ L +T + + + +E ++ +L+K+ +QEA KE+ + E+ +
Sbjct: 939 HI----LNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQ 994
Query: 497 DHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSD 556
E++ L + + + + E N +E T + E D+ E+K +
Sbjct: 995 --KEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLN 1052
Query: 557 QQGEALDSS---QKKTKNKKKKNKKKKSPVPVETLKDVKKELTY-------QNTDLSEIK 606
QQ E L Q + K ++ K+K + +++ KE+T+ Q+T L+E++
Sbjct: 1053 QQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQ 1112
Query: 607 EEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTA 666
E+ + KS S + + ++ + E ++ N +K + L ++ +++
Sbjct: 1113 EQLKQKSAHVNSLAQDETKLKAH---------LEKLEVDLNKSLKENTFLQEQLVELKML 1163
Query: 667 AEE 669
AEE
Sbjct: 1164 AEE 1166
Score = 41.6 bits (96), Expect = 0.003
Identities = 120/575 (20%), Positives = 216/575 (37%), Gaps = 76/575 (13%)
Query: 124 SISI-DTEASIREIK-----ELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVS 177
SIS+ + EA+I ++ E EL DQ+QD+ K KE +L +V++ K
Sbjct: 1386 SISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNK---F 1442
Query: 178 NAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKN---KEFEREKHAHSILQFQF 234
+ ++ F +T+K++ ++LE + E+ + E+ N +E +++ L+ +
Sbjct: 1443 SEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEM 1502
Query: 235 AEVKEALKQREEMLEKHGIILNSEIATNGETSD--------------TLNNVGYQGPT-- 278
+ K ++++E LE L S+ A E D L N Q
Sbjct: 1503 EDDKSKMEKKESNLETE---LKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEH 1559
Query: 279 KMTKEELNALKSTGDGTLGRASEVEVK-----NEIVA-----NVGKREILHNTEKEQHTE 328
K ++L + G+ R E E K N++ + K+E+ H + E
Sbjct: 1560 KELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKE 1619
Query: 329 DTVKDCVD-IEVFPAGENTE-DQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTV 386
+ +K D +E A + E +K+ + A L E++ Q + S L E
Sbjct: 1620 EELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNT 1679
Query: 387 QVESNE---------VMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGT 437
+++ E + ++ T + P + + E + V + E+ +
Sbjct: 1680 KLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKIS 1739
Query: 438 VASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQE---AAEPKEVPAHSTEV 494
V L +K + V QE E + E QE E E H +
Sbjct: 1740 VLQRNLTEK-------EKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQS 1792
Query: 495 GRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTV-DTQNEPLDMKEPDEE 553
H +EE EE + + V G + N Q V D + L KE +
Sbjct: 1793 MIGHLQEELEEKNKKYSLIVAQHV--EKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQ 1850
Query: 554 KSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKS 613
+Q+ + LDS + K + ++ + + + + + T+L E EE+ KS
Sbjct: 1851 ILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKS 1910
Query: 614 ----TDRKSAVEAQNE-------VTENPKQKIAAE 637
S +EAQ+ E KQK+ E
Sbjct: 1911 HLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKE 1945
Score = 30.0 bits (66), Expect = 9.0
Identities = 44/214 (20%), Positives = 83/214 (38%), Gaps = 29/214 (13%)
Query: 567 KKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEV 626
+ KN ++ ++ K V ET + + + L E+KEEE + R + Q E
Sbjct: 349 RDAKNLIEQLEQDKGMVIAETKRQMHETL--------EMKEEEIAQLRSRIKQMTTQGEE 400
Query: 627 TENPKQKIAAESSENVD-------CPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDF 679
K+K + E ++ E + KL ++D++ ++ +EE
Sbjct: 401 LREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEE---------- 450
Query: 680 EDDTVQSSGPRAGGEELD---EGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQ 736
E ++Q R E +D + + AK+ + A + E + E E Q
Sbjct: 451 ERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQ 510
Query: 737 DISDACEAESTERCEMSEHPSQTVRKALDSNSLE 770
+ A E +E ++S+ Q AL+ L+
Sbjct: 511 -MKVALEKSQSEYLKISQEKEQQESLALEELELQ 543
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 60.8 bits (146), Expect = 5e-09
Identities = 139/713 (19%), Positives = 282/713 (39%), Gaps = 89/713 (12%)
Query: 18 EAQKLAEARLAAKRAARAEAR-EIRMKEL-ERQQKEEDSERYSRRSRRNTSASDEDERMS 75
EA LA+A + + + + E ++KE+ ER + EE+ +R + +
Sbjct: 898 EADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKD 957
Query: 76 VGSRGSLRVEERPEKDFTEKGSRN----MPGLSAATLASLGGTSSRRGSGDTSISIDTEA 131
+ + EK TE +N M GL T+A L D +
Sbjct: 958 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE-TIAKLTKEKKALQEAHQQTLDDLQM 1016
Query: 132 SIREIKELNE----LKDQIQDVEGKYMQGLK---EMKDSLAEVEEKYKKAMVSNAQLDNE 184
++ L + L+ Q+ D+EG Q K +++ + ++E K A S +N+
Sbjct: 1017 EEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTEND 1076
Query: 185 K--------------TNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSIL 230
K +N +++ + + ++L++++ E + + EE +E E E+ + +
Sbjct: 1077 KQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKA 1136
Query: 231 QFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKS 290
+ Q +++ L++ E LE+ G +++I N + + K + +S
Sbjct: 1137 EKQRSDLSRELEEISERLEEAGGATSAQIEMNKKRE-----------AEFQKMRRDLEES 1185
Query: 291 TGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTED-Q 349
T A+ + + VA +G++ + + ++ + + K + +E+ N E
Sbjct: 1186 TLQHEATAAALRKKHADSVAELGEQ--IDSLQRVKQKLEKEKSELKMEINDLASNMETVS 1243
Query: 350 KSSEDTAPFLGTLAGATYE----EQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPL 405
K+ + TL E E+ Q +++ S + + ES E D++
Sbjct: 1244 KAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMV- 1302
Query: 406 EPSNCWSDLDGGNH--TENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCM---VEV 460
S L G T+ + E Q+EE+ T A L H+ + HD + E
Sbjct: 1303 ------SQLSRGKQAFTQQIEELK-RQLEEE--TKAKSTLAHALQSARHDCDLLREQYEE 1353
Query: 461 PQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEET---GLRDEKPIKTE 517
QE + + K N E A+ + + + R EE ++ L+D +
Sbjct: 1354 EQEAKAELQRGMSK--ANSEVAQWR-TKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEA 1410
Query: 518 VPGSPAG---TEGNCQEATGPSTVDTQNE-----PLDMKEPD--------EEKSDQQGEA 561
V A T+ Q +D + LD K+ + ++K ++
Sbjct: 1411 VNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAE 1470
Query: 562 LDSSQKKTKNK-----KKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDR 616
L++SQK++++ K KN ++S +ETLK K L + +DL+E + E K
Sbjct: 1471 LEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTE-QIAEGGKHIHE 1529
Query: 617 KSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEE 669
V+ Q + ++ Q E+ +++ E +++ +L+Q ++ E
Sbjct: 1530 LEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAE 1582
Score = 44.7 bits (104), Expect = 4e-04
Identities = 69/341 (20%), Positives = 138/341 (40%), Gaps = 28/341 (8%)
Query: 7 AQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRNTS 66
A +++I+ L + ++ +A+ A ++ + +L R+Q EE+ E + R +
Sbjct: 1311 AFTQQIEELKRQLEEETKAKSTLAHALQSARHDC---DLLREQYEEEQEAKAELQRGMSK 1367
Query: 67 ASDE--DERMSVGSRGSLRVEERPE--KDFTEKGSRNMPGLSAAT--LASLGGTSSRRGS 120
A+ E R + R EE E K ++ + A ASL T R +
Sbjct: 1368 ANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQN 1427
Query: 121 GDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQ 180
+ ID E S L++ + V ++ Q +E + L +++ + +
Sbjct: 1428 EVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFK 1487
Query: 181 LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA 240
+ N + ++TLK L++++++ Q E K + L + +E++ +
Sbjct: 1488 VKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTS 1547
Query: 241 LKQREEMLE-KHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALK---------- 289
L++ E LE + G IL ++ N S+ + + EEL+ LK
Sbjct: 1548 LEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEK------DEELDQLKRNHLRVVESM 1601
Query: 290 -STGDGTL-GRASEVEVKNEIVANVGKREILHNTEKEQHTE 328
ST D + R + +K ++ ++ + EI N Q E
Sbjct: 1602 QSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAE 1642
Score = 32.7 bits (73), Expect = 1.4
Identities = 101/591 (17%), Positives = 217/591 (36%), Gaps = 63/591 (10%)
Query: 93 TEKGSRNMPGLSAATLASLGGTSSRRGSGD----------TSISIDTEASIREIKELNEL 142
TEK NM T L T ++R + + + +A + + E
Sbjct: 849 TEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEER 908
Query: 143 KDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLEL 202
DQ+ + + +KE+ + + EE + +L++E + +D L+ L ++
Sbjct: 909 CDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 968
Query: 203 EEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATN 262
E++ + + + +E + L + ++EA +Q + L+ +N+
Sbjct: 969 EKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAK 1028
Query: 263 GETSDTLNNVGYQGPTKMTKE-----ELNALKSTGDGTLGRASEVEVKNEIVANVGKREI 317
+ ++++ +G + K+ E K GD L + S ++ +N+ K+++
Sbjct: 1029 TKLEQQVDDL--EGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTEND------KQQL 1080
Query: 318 LHNTEKEQHTEDTVKDCVDIEVFPAGE--------NTEDQKSSEDTAPFLGTLAGATYEE 369
+K++ ++ ++ E A + ++ E+ + A A +
Sbjct: 1081 NEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1140
Query: 370 QVQSQILE--SSSLPE----NTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGG----NH 419
S+ LE S L E + Q+E N+ A + R LE S + H
Sbjct: 1141 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKH 1200
Query: 420 TENVGEAA----------------VTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQE 463
++V E ++++ + +AS S + C Q
Sbjct: 1201 ADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQL 1260
Query: 464 LETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGL-RDEKPIKTEVPGSP 522
E T ++ N+ +A+ + S E R +E++ + L R ++ ++
Sbjct: 1261 SEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELK 1320
Query: 523 AGTEGNCQ-EATGPSTVDTQNEPLD-MKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKK 580
E + ++T + + D ++E EE+ + + E K + K +
Sbjct: 1321 RQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYE 1380
Query: 581 SPV--PVETLKDVKKELTYQNTDLSEIKEEEQVKSTD-RKSAVEAQNEVTE 628
+ E L++ KK+L + D E E K K+ QNEV +
Sbjct: 1381 TDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVED 1431
Score = 30.8 bits (68), Expect = 5.3
Identities = 20/114 (17%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Query: 137 KELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLK 196
K++ +L+ +++++E + K +++ + + ++ Q + ++ N + L+
Sbjct: 1814 KQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNIL----RLQ 1869
Query: 197 DMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEK 250
D++ +L+ ++ +RQ EE ++ LQ + E KE E + K
Sbjct: 1870 DLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNK 1923
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 59.7 bits (143), Expect = 1e-08
Identities = 75/365 (20%), Positives = 135/365 (36%), Gaps = 30/365 (8%)
Query: 459 EVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEV 518
E ++ E GH E+ NQE E E E EEE E+ G E+ EV
Sbjct: 708 EEQEQKEREQGHQKER---NQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEV 764
Query: 519 PGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKK 578
G EG ++ + E D E +EE+++ +GE + + + ++ K
Sbjct: 765 EGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKG 824
Query: 579 KKSPVPVETLKDV-------------------KKELTYQNTDLSEIKEEEQVKSTDRKSA 619
++ E + K E + + E EE + + + +
Sbjct: 825 EREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGE 884
Query: 620 VEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDF 679
E + E +++ E E + + +GK ++EG++ + EE +G+ D
Sbjct: 885 GEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDG 944
Query: 680 EDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDIS 739
E + + G G EE EG ++ +G + E + E+ + E E ++
Sbjct: 945 EGEGEEEEGEWEGEEEEGEGEGEE----EGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGE 1000
Query: 740 DACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKG 799
+ E E E E V ++ E + G E G E RE G E
Sbjct: 1001 EEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEG----EEREKEGEGEENR 1056
Query: 800 KSKED 804
+++E+
Sbjct: 1057 RNREE 1061
Score = 47.8 bits (112), Expect = 4e-05
Identities = 72/375 (19%), Positives = 138/375 (36%), Gaps = 50/375 (13%)
Query: 456 CMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEE----GEETGLRDE 511
C V Q + + + + F+++E P+E G E+E E +
Sbjct: 559 CKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGG 618
Query: 512 KPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKN 571
+ KTE+ + E S + ++ P E + D E S + ++
Sbjct: 619 RKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGP-------EGRGDGTCEEGSSGAEHWQD 671
Query: 572 KKK-KNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENP 630
+++ K +K K +E + +KEL + EE++ K ++ E E+ E
Sbjct: 672 EEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGG 731
Query: 631 KQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLA----------------DG 674
+++ E D E + + +GK + EG++V+ E+ +G
Sbjct: 732 EEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEG 791
Query: 675 DTLDFEDDTVQSSG--PRAGGE----ELDEGVA-KDNAKIDGATQSSPAEPKSEDADRCT 727
D + E++ + G GGE E++EG ++ + +G + E + E+ +
Sbjct: 792 DQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEG-- 849
Query: 728 LPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPE 787
E E + + E E E E E E ++ G E G E
Sbjct: 850 -EEEEGEGKGEEEGEEGEGEEEGEEGEGEG------------EEEEGEGEGEEEGEGEGE 896
Query: 788 SREDTRGGNEKGKSK 802
E G E+G+ +
Sbjct: 897 EEEGEGEGEEEGEGE 911
Score = 42.4 bits (98), Expect = 0.002
Identities = 72/317 (22%), Positives = 131/317 (41%), Gaps = 37/317 (11%)
Query: 499 NEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQ 558
+E +E+ L ++ ++ E P E STV++ E D+ S
Sbjct: 451 SERNLQESVLSEQDLMQPEEPDYLLDEMTKEAEIDNSSTVESLGETTDILNMTHIMS--- 507
Query: 559 GEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTY-QNTDLSEIKEEEQVKSTDRK 617
L+S++K K + +KK+ +T+ ++ ++ +N D E +E ++K
Sbjct: 508 ---LNSNEKSLKLSPVQKQKKQ-----QTIGELTQDTALTENDDSDEYEEMSEMKEGKAC 559
Query: 618 SAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTL 677
+Q P I A S E V+ PE + +G D +G+ ++ +EV A+
Sbjct: 560 KQHVSQGIFMTQPATTIEAFSDEEVEIPE----EKEGAEDSKGNGIE--EQEVEAN---- 609
Query: 678 DFEDDTVQSSGPRAGGEELDEGVAKDNAKI-DGATQS-SPAEPKSEDADRCTLPEHESPS 735
++ V+ G R E+ D A++ +G +S AE E T E S +
Sbjct: 610 ---EENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGA 666
Query: 736 QDISDACEAESTE----RCEMSEHPSQTVRKALDS---NSLENDDLSAPGREPGHFNPES 788
+ D E E E R EM E P + ++ + + ++ RE GH +
Sbjct: 667 EHWQDE-EREKGEKDKGRGEM-ERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERN 724
Query: 789 REDTRGGNEK-GKSKED 804
+E GG E+ G+ +E+
Sbjct: 725 QEMEEGGEEEHGEGEEE 741
Score = 40.0 bits (92), Expect = 0.009
Identities = 89/420 (21%), Positives = 145/420 (34%), Gaps = 49/420 (11%)
Query: 203 EEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATN 262
EEQ + R Q +K + E E+ + E +E REE EK G E
Sbjct: 708 EEQEQKEREQGHQKERNQEMEEGGEE----EHGEGEEEEGDREEEEEKEG-----EGKEE 758
Query: 263 GETSDTLNNVGYQ----------GPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANV 312
GE + + G + +EE + + + T GR E E E+
Sbjct: 759 GEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGE 818
Query: 313 GKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQ-KSSEDTAPFLGTLAGATYEEQV 371
+ E+E+ E ++ E GE E + K E+ G G E +
Sbjct: 819 VEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEG 878
Query: 372 QSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQV 431
+ + E E + E E G ++ E + +G E GE +
Sbjct: 879 EEEEGEGEGEEEGEGEGEEEEGEGEGEE------EGEGEGEEEEGEGKGEEEGEEGEGEG 932
Query: 432 EEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEK-EFTNQEAAEPKEVPAH 490
EE+ G G +D ++ E E E G E+ E +E E
Sbjct: 933 EEEEGE------GEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEG 986
Query: 491 STEVGRDHNEEEGEETGLRDEK-----------PIKTEVPGSPAGTEGNCQEATGPSTV- 538
E + EEEGEE G +E+ ++ EV G EG +E
Sbjct: 987 EGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEER 1046
Query: 539 ----DTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKE 594
+ + + +E +EE+ Q + ++++ + KK K K V K +K+
Sbjct: 1047 EKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKK 1106
Score = 35.4 bits (80), Expect = 0.21
Identities = 121/610 (19%), Positives = 211/610 (34%), Gaps = 76/610 (12%)
Query: 20 QKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRNTSASDEDERMSVGSR 79
Q +++ + A EA E+ +++ + + + + A++E+ ++ G +
Sbjct: 561 QHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRK 620
Query: 80 GSLRV--EERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIK 137
+ ++ +K +G G + G + GS D E E
Sbjct: 621 EKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGE-- 678
Query: 138 ELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKD 197
KD+ + + +G KE LAE EE K+ Q + E+ +Q + ++
Sbjct: 679 -----KDKGRGEMERPGEGEKE----LAEKEEWKKRDGEEQEQKEREQG---HQKERNQE 726
Query: 198 MLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVK------EALKQREEMLEKH 251
M EE+ E EE ++E E EK + + EV+ E +++EE K
Sbjct: 727 MEEGGEEEHGEGEE--EEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKE 784
Query: 252 ---------GIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL--GRAS 300
G E GE + V G + K E + G+G G
Sbjct: 785 EKGEEEGDQGEGEEEETEGRGEEKEEGGEVE-GGEVEEGKGEREEEEEEGEGEEEEGEGE 843
Query: 301 EVEVKNEIVANVGK-REILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFL 359
E E + E GK E E E+ E+ + + E GE + + E+
Sbjct: 844 EEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGE 903
Query: 360 GTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWS------D 413
G G E+ + + E + E E G +D E W +
Sbjct: 904 GEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGE 963
Query: 414 LDGGNHTENVGEAAVTQVEEQAGTVASCPL-----------GHSDDTVYHDDKCMVEVPQ 462
+G E GE + EE+ G G + +++ EV
Sbjct: 964 GEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEG 1023
Query: 463 ELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSP 522
E+E G +E +E E +E E R+ EEE E
Sbjct: 1024 EVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEE------------------ 1065
Query: 523 AGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSP 582
EG QE TG + Q+ K + S + G+ +K N + K+++S
Sbjct: 1066 ---EGKYQE-TGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSK 1121
Query: 583 VPVETLKDVK 592
+PV++ + +K
Sbjct: 1122 MPVQSKRLLK 1131
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 58.2 bits (139), Expect = 3e-08
Identities = 79/378 (20%), Positives = 149/378 (39%), Gaps = 56/378 (14%)
Query: 446 SDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEV----------G 495
SDDT+ ++ + + +T S +E N++ + K ST+ G
Sbjct: 140 SDDTIQASEESAPQGQDSAQDTTSES--RELDNEDRVDSKPEGGDSTQESESEEHWVGGG 197
Query: 496 RDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKS 555
D G+ + L DE ++++ P S GN ++ MK + ++
Sbjct: 198 SDGESSHGDGSELDDEG-MQSDDPESIRSERGN-----------SRMNSAGMKSKESGEN 245
Query: 556 DQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTD 615
+Q DS + + +KS + E D + EL NT + E+K + S
Sbjct: 246 SEQANTQDSGGSQLLEHPSRKIFRKSRISEE---DDRSELDDNNT-MEEVKSDSTENSNS 301
Query: 616 RKSAV-----EAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEV 670
R + + +++ + E+ K+ ++ E S+NVD P + + QE + EEV
Sbjct: 302 RDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSS--ESQEEV 359
Query: 671 LAD--GD----TLDFEDDTVQSSGPR---------AGGEELDEGVAKDNAKIDGATQSSP 715
+++ GD T + +D S + E +E ++++ ++ SP
Sbjct: 360 VSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESP 419
Query: 716 AEPKSEDADRCT-LPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDL 774
P+ E++ L H S ++ S+ +E E + R DSNS E+
Sbjct: 420 ESPEDENSSSQEGLQSHSSSAESQSEESHSE-----EDDSDSQDSSRSKEDSNSTESKSS 474
Query: 775 SAPGREPGHFNPESREDT 792
S + + ESR+ T
Sbjct: 475 SEEDGQLKNIEIESRKLT 492
Score = 47.0 bits (110), Expect = 7e-05
Identities = 72/422 (17%), Positives = 163/422 (38%), Gaps = 42/422 (9%)
Query: 344 ENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRT 403
++ ++ S +DT + G ++ + L S ++T+Q D T
Sbjct: 102 KDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDT 161
Query: 404 PLEPSNCWSDLDGGNHTENVGEAAVTQVEEQA-----GTVASCPLGHSDDTVYHDDKCMV 458
E +LD + ++ E + E ++ G + H D + D+
Sbjct: 162 TSESR----ELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQS 217
Query: 459 EVPQELETSTGHSL--------------EKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGE 504
+ P+ + + G+S ++ Q++ + + S ++ R E +
Sbjct: 218 DDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEED 277
Query: 505 ETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDS 564
+ D+ EV TE + TG S ++ ++ E S ++ + +D
Sbjct: 278 DRSELDDNNTMEEVKSD--STENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDG 335
Query: 565 SQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTD--LSEIKEEEQVKSTDRKSAVEA 622
++ + + ++ S E+ ++V E N D S ++++E S++ S+
Sbjct: 336 PSSESSQEANLSSQENSS---ESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTL 392
Query: 623 QNEVTENPKQKIAAESSENV----DCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLD 678
+ +E+ +++ +ESSE++ + PE+P+ + QEG +Q+ + + +
Sbjct: 393 SHSKSESREEQADSESSESLNFSEESPESPED--ENSSSQEG--LQSHSSSAESQSEESH 448
Query: 679 FEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDI 738
E+D S E+ + +K +++ DG ++ E + D H P D
Sbjct: 449 SEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVD----AYHNKPIGDQ 504
Query: 739 SD 740
D
Sbjct: 505 DD 506
Score = 37.7 bits (86), Expect = 0.043
Identities = 52/254 (20%), Positives = 103/254 (40%), Gaps = 28/254 (11%)
Query: 55 ERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGT 114
E SR+ R + S+ED+R + ++ E + D TE + GLS
Sbjct: 261 EHPSRKIFRKSRISEEDDRSELDDNNTM---EEVKSDSTENSNSRDTGLS---------- 307
Query: 115 SSRRGSGDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKA 174
RR D++ +E + N +++ Q+V+G + +E S E + ++
Sbjct: 308 QPRR---------DSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEE 358
Query: 175 MVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQF 234
+VS ++ DN Y V+ +D E+ S K++ E + + S F
Sbjct: 359 VVSESRGDNPDPTTSY-VEDQEDSDSSEED---SSHTLSHSKSESREEQADSESSESLNF 414
Query: 235 AEVKEALKQREEMLEKHGIILNSEIA-TNGETSDTLNNVGYQGPTKMTKEELNALKSTGD 293
+E + E + G+ +S A + E S + + + +KE+ N+ +S
Sbjct: 415 SEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSS 474
Query: 294 GTL-GRASEVEVKN 306
G+ +E+++
Sbjct: 475 SEEDGQLKNIEIES 488
Score = 31.6 bits (70), Expect = 3.1
Identities = 43/200 (21%), Positives = 74/200 (37%), Gaps = 26/200 (13%)
Query: 618 SAVEAQNEVTENPKQKIAAESSENVDCPENPKI-KLDGKL--------DQEGDDVQTAAE 668
S V ++ + E+P + +S E + ++ I +L G D + DD + +
Sbjct: 54 SKVSSEEQANEDPSD--STQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGD 111
Query: 669 EVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTL 728
+ D D+ D + R G +E + D S + P+ +D+ + T
Sbjct: 112 DTFGDDDSGPGPKDRQEGGNSRLGSDEDSD---------DTIQASEESAPQGQDSAQDTT 162
Query: 729 PE-HESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPE 787
E E ++D D+ + E + + SE V D S D +PE
Sbjct: 163 SESRELDNEDRVDS-KPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPE 221
Query: 788 SREDTRGGNEKG----KSKE 803
S RG + KSKE
Sbjct: 222 SIRSERGNSRMNSAGMKSKE 241
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 58.2 bits (139), Expect = 3e-08
Identities = 79/378 (20%), Positives = 149/378 (39%), Gaps = 56/378 (14%)
Query: 446 SDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEV----------G 495
SDDT+ ++ + + +T S +E N++ + K ST+ G
Sbjct: 124 SDDTIQASEESAPQGQDSAQDTTSES--RELDNEDRVDSKPEGGDSTQESESEEHWVGGG 181
Query: 496 RDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKS 555
D G+ + L DE ++++ P S GN ++ MK + ++
Sbjct: 182 SDGESSHGDGSELDDEG-MQSDDPESIRSERGN-----------SRMNSAGMKSKESGEN 229
Query: 556 DQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTD 615
+Q DS + + +KS + E D + EL NT + E+K + S
Sbjct: 230 SEQANTQDSGGSQLLEHPSRKIFRKSRISEE---DDRSELDDNNT-MEEVKSDSTENSNS 285
Query: 616 RKSAV-----EAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEV 670
R + + +++ + E+ K+ ++ E S+NVD P + + QE + EEV
Sbjct: 286 RDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSS--ESQEEV 343
Query: 671 LAD--GD----TLDFEDDTVQSSGPR---------AGGEELDEGVAKDNAKIDGATQSSP 715
+++ GD T + +D S + E +E ++++ ++ SP
Sbjct: 344 VSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESP 403
Query: 716 AEPKSEDADRCT-LPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDL 774
P+ E++ L H S ++ S+ +E E + R DSNS E+
Sbjct: 404 ESPEDENSSSQEGLQSHSSSAESQSEESHSE-----EDDSDSQDSSRSKEDSNSTESKSS 458
Query: 775 SAPGREPGHFNPESREDT 792
S + + ESR+ T
Sbjct: 459 SEEDGQLKNIEIESRKLT 476
Score = 47.0 bits (110), Expect = 7e-05
Identities = 72/422 (17%), Positives = 163/422 (38%), Gaps = 42/422 (9%)
Query: 344 ENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRT 403
++ ++ S +DT + G ++ + L S ++T+Q D T
Sbjct: 86 KDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDT 145
Query: 404 PLEPSNCWSDLDGGNHTENVGEAAVTQVEEQA-----GTVASCPLGHSDDTVYHDDKCMV 458
E +LD + ++ E + E ++ G + H D + D+
Sbjct: 146 TSESR----ELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQS 201
Query: 459 EVPQELETSTGHSL--------------EKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGE 504
+ P+ + + G+S ++ Q++ + + S ++ R E +
Sbjct: 202 DDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEED 261
Query: 505 ETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDS 564
+ D+ EV TE + TG S ++ ++ E S ++ + +D
Sbjct: 262 DRSELDDNNTMEEVKSD--STENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDG 319
Query: 565 SQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTD--LSEIKEEEQVKSTDRKSAVEA 622
++ + + ++ S E+ ++V E N D S ++++E S++ S+
Sbjct: 320 PSSESSQEANLSSQENSS---ESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTL 376
Query: 623 QNEVTENPKQKIAAESSENV----DCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLD 678
+ +E+ +++ +ESSE++ + PE+P+ + QEG +Q+ + + +
Sbjct: 377 SHSKSESREEQADSESSESLNFSEESPESPED--ENSSSQEG--LQSHSSSAESQSEESH 432
Query: 679 FEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDI 738
E+D S E+ + +K +++ DG ++ E + D H P D
Sbjct: 433 SEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVD----AYHNKPIGDQ 488
Query: 739 SD 740
D
Sbjct: 489 DD 490
Score = 37.7 bits (86), Expect = 0.043
Identities = 52/254 (20%), Positives = 103/254 (40%), Gaps = 28/254 (11%)
Query: 55 ERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGT 114
E SR+ R + S+ED+R + ++ E + D TE + GLS
Sbjct: 245 EHPSRKIFRKSRISEEDDRSELDDNNTM---EEVKSDSTENSNSRDTGLS---------- 291
Query: 115 SSRRGSGDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKA 174
RR D++ +E + N +++ Q+V+G + +E S E + ++
Sbjct: 292 QPRR---------DSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEE 342
Query: 175 MVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQF 234
+VS ++ DN Y V+ +D E+ S K++ E + + S F
Sbjct: 343 VVSESRGDNPDPTTSY-VEDQEDSDSSEED---SSHTLSHSKSESREEQADSESSESLNF 398
Query: 235 AEVKEALKQREEMLEKHGIILNSEIA-TNGETSDTLNNVGYQGPTKMTKEELNALKSTGD 293
+E + E + G+ +S A + E S + + + +KE+ N+ +S
Sbjct: 399 SEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSS 458
Query: 294 GTL-GRASEVEVKN 306
G+ +E+++
Sbjct: 459 SEEDGQLKNIEIES 472
Score = 30.4 bits (67), Expect = 6.9
Identities = 34/152 (22%), Positives = 55/152 (36%), Gaps = 15/152 (9%)
Query: 657 DQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPA 716
D + DD + ++ D D+ D + R G +E + D S +
Sbjct: 84 DDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSD---------DTIQASEES 134
Query: 717 EPKSEDADRCTLPE-HESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLS 775
P+ +D+ + T E E ++D D+ + E + + SE V D S D
Sbjct: 135 APQGQDSAQDTTSESRELDNEDRVDS-KPEGGDSTQESESEEHWVGGGSDGESSHGDGSE 193
Query: 776 APGREPGHFNPESREDTRGGNEKG----KSKE 803
+PES RG + KSKE
Sbjct: 194 LDDEGMQSDDPESIRSERGNSRMNSAGMKSKE 225
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 57.0 bits (136), Expect = 7e-08
Identities = 97/430 (22%), Positives = 166/430 (38%), Gaps = 48/430 (11%)
Query: 364 GATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENV 423
G+ +E+ +Q + ++ Q + E + AP+ E + G+ E
Sbjct: 1807 GSGHEDNLQGEAAAGGD--QDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAE 1864
Query: 424 GEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAE 483
GEA + +A S+D + EV E E + EKE E
Sbjct: 1865 GEAQPESEDVEAPEAEGEAQPESEDV--ETPEAEWEVQPESEGAEAPEAEKE----AQPE 1918
Query: 484 PKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNE 543
+ V A TE G D E EG E +E + E P QEA ++E
Sbjct: 1919 TESVEALETE-GEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAE--EEAQPESE 1975
Query: 544 PLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDL- 602
++ E + E + +GEA S+ ++P +++ ++E ++ +
Sbjct: 1976 DVEALEVEVETQEAEGEAQPESEDV-----------EAPEAEGEMQEAEEEAQPESDGVE 2024
Query: 603 ----SEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQ 658
SE +E ++V+ +K+ +AQ E A E+ E E + +G+
Sbjct: 2025 AQPKSEGEEAQEVEGETQKTEGDAQPESDGVE----APEAEEEAQEAEGEVQEAEGEAHP 2080
Query: 659 EGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEP 718
E +DV A+E A+G+ + ++ P A EG A+ I+ A+P
Sbjct: 2081 ESEDVD--AQE--AEGEA---QPESEGVEAPEA------EGEAQKAEGIEAPETEGEAQP 2127
Query: 719 KSEDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPG 778
+SE + PE E +Q S+ EA+ E E ++A + E + + AP
Sbjct: 2128 ESEGIE---APEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPE 2184
Query: 779 REPGHFNPES 788
E G PES
Sbjct: 2185 AE-GEAQPES 2193
Score = 51.2 bits (121), Expect = 4e-06
Identities = 107/546 (19%), Positives = 207/546 (37%), Gaps = 76/546 (13%)
Query: 221 EREKHAHSILQFQFAEVKEALKQREEMLEK---------HGIILNSEIATNGET------ 265
ERE H+ +E+ EA ++ E + E+ H L E A G+
Sbjct: 1771 EREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSD 1830
Query: 266 -SDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKE 324
++ + +G + E + A ++ GD ++ A + E +
Sbjct: 1831 GAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEA------Q 1884
Query: 325 QHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLA-------------GATYEEQV 371
+ED + EV P E E ++ ++ P ++ GA +E
Sbjct: 1885 PESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAE 1944
Query: 372 QS-QILESSSLPENTVQVESNEVM--GAPDDRTRTPLEPSNCWSDLDGGNHTENVG-EAA 427
++ Q E + PE+ V +ES E P+ LE + +G E+ EA
Sbjct: 1945 EAAQEAEGQTQPESEV-IESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAP 2003
Query: 428 VTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEV 487
+ E Q + P D V K E QE+E T + + A+P+
Sbjct: 2004 EAEGEMQEAEEEAQP---ESDGVEAQPKSEGEEAQEVEGETQKT-------EGDAQPESD 2053
Query: 488 PAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDM 547
+ E + E EGE + E P + + QEA G + Q E +
Sbjct: 2054 GVEAPEAEEEAQEAEGEVQ--------EAEGEAHPESEDVDAQEAEG----EAQPESEGV 2101
Query: 548 KEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKE 607
+ P+ E Q+ E +++ + + + + +++ ++P + + + Q+ + E
Sbjct: 2102 EAPEAEGEAQKAEGIEAPETEGE-AQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPE 2160
Query: 608 EEQVKSTDRKSAVEAQNEVTENPKQKIAAE-SSENVDCPENPKIKLDGKLDQEGDDVQTA 666
E +++ + + + + E E P+ + A+ SE ++ PE + + + + EG + A
Sbjct: 2161 SEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPE---AEGEAQPELEGVEAPEA 2217
Query: 667 AEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRC 726
EE + + ++ P A GE E + + G+ Q S + +SE+A
Sbjct: 2218 EEEAQPEPEGVET---------PEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASES 2268
Query: 727 TLPEHE 732
+ P E
Sbjct: 2269 SSPVPE 2274
Score = 40.4 bits (93), Expect = 0.007
Identities = 50/219 (22%), Positives = 90/219 (41%), Gaps = 22/219 (10%)
Query: 598 QNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLD 657
+NT E++ EE + T+ + E ++ E ++ E E V E + + +G+ +
Sbjct: 1294 ENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQE--EGVQLEETKETEGEGQQE 1351
Query: 658 QEG---DDVQTAAEEVLADGDTLDFEDDTVQSSGPRAG--GEELDEGVAKDNAKIDGA-- 710
+E + +T E + +G L+ + GP G GE L+EG+ ++ +G+
Sbjct: 1352 EEAQLEEIEETGGEGLQEEGVQLEEVKE-----GPEGGLQGEALEEGLKEEGLPEEGSVH 1406
Query: 711 ----TQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTER-CEMSEHPSQTVRKALD 765
+++S + K D E + ++ C AE TE E H S+T A +
Sbjct: 1407 GQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEPPSHLSETDPSASE 1466
Query: 766 SNS---LENDDLSAPGREPGHFNPESREDTRGGNEKGKS 801
S LE PG + T+G E+ S
Sbjct: 1467 RQSGSQLEPGLEKPPGATMMGQEHTQAQPTQGAAERSSS 1505
Score = 36.6 bits (83), Expect = 0.096
Identities = 132/639 (20%), Positives = 221/639 (34%), Gaps = 91/639 (14%)
Query: 204 EQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNG 263
EQLAE+ Q EE E +E LQ + +++E + EE L++ G+ L T G
Sbjct: 1290 EQLAENTVQ-EEVQLEETKEGTEGEGLQEEAVQLEET--KTEEGLQEEGVQLEETKETEG 1346
Query: 264 ETSDT----LNNVGYQGPTKMTKE--ELNALKSTGDGTL-GRASEVEVKNEIVANVGKRE 316
E L + G + +E +L +K +G L G A E +K E + G
Sbjct: 1347 EGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGS-- 1404
Query: 317 ILHNTE---------KEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAP--FLGTLAGA 365
+H E K +D V++ + E + + E T P L +
Sbjct: 1405 -VHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEPPSHLSETDPS 1463
Query: 366 TYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENV-- 423
E Q SQ+ P + P C + LD +V
Sbjct: 1464 ASERQSGSQLEPGLEKPPGATMMGQEHTQAQPTQGAAERSSSVACSAALDCDPIWVSVLL 1523
Query: 424 --GEAAVTQVEEQAGTVASCPLGHSDDTVYHD--DKCMVEVPQELETSTGHSLEK---EF 476
E A A G D+ + + +V Q L+ ST L+K
Sbjct: 1524 KKTEKAFLAHLASAVAELRARWGLQDNDLLDQMAAELQQDVAQRLQDSTKRELQKLQGRA 1583
Query: 477 TNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPS 536
P+E A + E+ + GLR+ G GP
Sbjct: 1584 GRMVLEPPRE--ALTGELLLQTQQRRHRLRGLRNLSAFSERTLG------------LGPL 1629
Query: 537 TVDTQNEP-LDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKEL 595
+ ++EP L + + +GE + + KK SP+ + +
Sbjct: 1630 SFTLEDEPALSTALGSQLGEEAEGEEFCPCEACVR-------KKVSPMSPKATMGATRGP 1682
Query: 596 TYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCP---ENPKIKL 652
+ DL +I + ++ + TD ++A A + +P + +E P + P +
Sbjct: 1683 IKEAFDLQQILQRKRGEHTDGEAAEVAPGKTHTDPTSTRTVQGAEGGLGPGLSQGPGV-- 1740
Query: 653 DGKLDQEGDDVQTAAEEVL---ADGDTLDFEDDTVQSSGPRAGGEEL------DEGVA-- 701
D D EG ++ A+GD + E + + + G EL EG++
Sbjct: 1741 DEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISER 1800
Query: 702 ----------KDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTERCE 751
+DN + + A +S+ A+ PE E +Q S+ EA E
Sbjct: 1801 GETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAE--- 1857
Query: 752 MSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESRE 790
++A E++D+ AP E G PES +
Sbjct: 1858 ------GDAQEAEGEAQPESEDVEAPEAE-GEAQPESED 1889
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 55.1 bits (131), Expect = 3e-07
Identities = 72/460 (15%), Positives = 163/460 (35%), Gaps = 21/460 (4%)
Query: 345 NTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTP 404
++ D +S D++ + G+ + +S SS +++ S++ + D
Sbjct: 831 DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSN---- 886
Query: 405 LEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQEL 464
E SN D N +++ + + + S +S D+ + +
Sbjct: 887 -ESSNSSDSSDSSNSSDS-------DSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938
Query: 465 ETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAG 524
S+ S + +N + ++S++ ++ + + + D S +
Sbjct: 939 SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS 998
Query: 525 TEGNCQEATGPS-TVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPV 583
N +++ S + D+ N D S ++ DSS + + +
Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058
Query: 584 PVETLKDVKKEL-TYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENV 642
D + ++D S+ E + S ++ +++ +++SS++
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1118
Query: 643 DCPENPKIKLDGKLDQEGDDVQTAAE--EVLADGDTLDFED--DTVQSSGPRAGGEELDE 698
D N D + D +++ + D+ D D D+ SS + D
Sbjct: 1119 DS-SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177
Query: 699 GVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHE--SPSQDISDACEAESTERCEMSEHP 756
+ D++ ++ SS + S+ +D + S S D SD+ ++ + S
Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS 1237
Query: 757 SQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGN 796
S + + SNS ++ D S N ES ++ GN
Sbjct: 1238 SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGN 1277
Score = 52.0 bits (123), Expect = 2e-06
Identities = 74/506 (14%), Positives = 169/506 (33%), Gaps = 19/506 (3%)
Query: 321 TEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSS 380
+E + D+ D D + +N++ SS + + + + + S SS
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSD 688
Query: 381 LPENTVQVESNEVMGAPDDRTRTPLEPSNCW----SDLDGGNHTENVGEAAVTQVEEQAG 436
+++ S+E + D + S+ SD D N +++ + + + +
Sbjct: 689 SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSD 748
Query: 437 TVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPA---HSTE 493
+ S S D+ D + S+ S + +N + + +S++
Sbjct: 749 SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808
Query: 494 VGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEE 553
+ + + + D S + + +++ S D+ N D
Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS 868
Query: 554 KSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEE-EQVK 612
S + DSS N+ + + ++D S + E
Sbjct: 869 DSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSN 928
Query: 613 STDRKSAVEAQN--EVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEV 670
S+D ++ ++ N + +++ +++SS + D N D D ++
Sbjct: 929 SSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDS-SNSSDSSDSNSSDSSDSSNSSDSSD 987
Query: 671 LADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPE 730
+D D+ SS + D + D++ ++ SS + S+ +D +
Sbjct: 988 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047
Query: 731 --------HESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPG 782
+ S S D SD+ ++ + S S++ + SNS ++ D S
Sbjct: 1048 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSD 1107
Query: 783 HFNPESREDTRGGNEKGKSKEDCTMS 808
+ D+ + S + S
Sbjct: 1108 SSDSSDSSDSSDSSNSSDSSDSSDSS 1133
Score = 51.6 bits (122), Expect = 3e-06
Identities = 55/315 (17%), Positives = 118/315 (37%), Gaps = 19/315 (6%)
Query: 497 DHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSD 556
D N E + R + ++ + GN ++ G D+ + D SD
Sbjct: 476 DANSESDNNSSSRGDASYNSD----ESKDNGNGSDSKGAEDDDSDSTS------DTNNSD 525
Query: 557 QQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDR 616
G + + K+ K K S + ++D S+ S+D
Sbjct: 526 SNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDS 585
Query: 617 KSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQ---EGDDVQTAAEEVLAD 673
S+ + ++ +++ +++SS++ D ++ D K D E D + ++ +D
Sbjct: 586 DSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSS-DSKSDSSKSESDSSDSDSKSDSSD 644
Query: 674 GDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHES 733
++ D D++ SS D + D++ ++ SS + S+ +D + S
Sbjct: 645 SNSSDSSDNS-DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSD----SSNSS 699
Query: 734 PSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTR 793
S D SD+ +++S++ + S S + S+S ++ + S N D+
Sbjct: 700 ESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 759
Query: 794 GGNEKGKSKEDCTMS 808
+ S + S
Sbjct: 760 DSSNSSDSSDSSDSS 774
Score = 47.8 bits (112), Expect = 4e-05
Identities = 72/558 (12%), Positives = 186/558 (33%), Gaps = 22/558 (3%)
Query: 256 NSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKR 315
+S+ + + ++SD+ ++ + + + + D + +S+ + N ++
Sbjct: 680 SSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSN 739
Query: 316 EILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQI 375
+ + D D ++ D S D++ + + + S
Sbjct: 740 SSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN-----SSDSNDSSNSSDS 794
Query: 376 LESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENV-----GEAAVTQ 430
+SS+ +++ +S++ + D + + SN D N +++ + + +
Sbjct: 795 SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSD 854
Query: 431 VEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAH 490
++ + S S D+ D E S+ S ++ ++++
Sbjct: 855 SSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDS 914
Query: 491 STEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEP 550
S + E + + S + N +++ S ++ D
Sbjct: 915 SDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSS 974
Query: 551 DEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQ 610
D S ++ DSS + + D + ++D S +
Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD-----SSNSSDSSNSSDSSN 1029
Query: 611 VKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEV 670
+ S ++ +++ ++ SS++ D ++ D + D ++E
Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS----DSSDSSDSSDSSDSSES- 1084
Query: 671 LADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPE 730
+D D+ SS + D + D++ ++ SS + S+ +D +
Sbjct: 1085 -SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143
Query: 731 HESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESRE 790
S S + SD+ ++ + S S + + SNS ++ D S +
Sbjct: 1144 -SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1202
Query: 791 DTRGGNEKGKSKEDCTMS 808
D+ ++ S + S
Sbjct: 1203 DSSDSSDSSDSSDSSDSS 1220
Score = 47.0 bits (110), Expect = 7e-05
Identities = 106/599 (17%), Positives = 212/599 (35%), Gaps = 65/599 (10%)
Query: 261 TNGETSDTLNN--VGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREIL 318
TNG T N VG G E++ ++ G G + + ++EI+ N + E
Sbjct: 154 TNGNTDKNTQNGDVGDAGHN----EDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEG- 208
Query: 319 HNTEKEQHTEDTVKDCVDIEVFP-----AGENTEDQKSSEDTAPFLGTLAGATYEEQVQS 373
+ +E + EV P AG + D S + A E++
Sbjct: 209 NTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAG 268
Query: 374 QILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNC--WSDLDGGN--HTENVGEAAVT 429
+SS N + + + G DD + + S+ + D +G H E G+
Sbjct: 269 NGKDSS----NNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSK 324
Query: 430 QVEEQAGTVASCPLGHSDDT--VYHDDKCMVE--VPQELET-STGHSLEKEFTNQEAAEP 484
E AG +DT + H + VE + +E ET + G S +K + +
Sbjct: 325 SEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSG 384
Query: 485 KEVPAHSTEVGRDHNEEEGEETGLRDEKPIKT-------EVPG-----------SPAGTE 526
G + E++G+ + + +KT E PG S G++
Sbjct: 385 NRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSD 444
Query: 527 GNCQ------------EATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKK 574
N + P++ D N D + S +G+A +S + N
Sbjct: 445 SNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNG 504
Query: 575 KNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKI 634
+ K ++ D + N + + ++ + + + + ++ +++
Sbjct: 505 SDSKGAEDDDSDSTSDTNN--SDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSD 562
Query: 635 AAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFED-----DTVQSSGP 689
+++SS++ N D D + + + D+ D D D+ SS
Sbjct: 563 SSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 622
Query: 690 RAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTER 749
++ + + + ++K D + +S + D+ + + S S D SD+ ++ S+
Sbjct: 623 KSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSD 682
Query: 750 CEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKGKSKEDCTMS 808
S + S + + SNS E+ D S + +S ++ S + S
Sbjct: 683 ---SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS 738
Score = 43.9 bits (102), Expect = 6e-04
Identities = 56/369 (15%), Positives = 130/369 (35%), Gaps = 15/369 (4%)
Query: 448 DTVYHDDKCMV-EVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEET 506
D+ DDK M + P + S G+ ++ ++ + +S E +D+ +
Sbjct: 451 DSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDE-SKDNGNGSDSKG 509
Query: 507 GLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQ 566
D+ ++ S + GN + D+ D + D S ++ DSS
Sbjct: 510 AEDDDSDSTSDTNNSDSNGNGNNGNDDNDKS-DSGKGKSDSSDSDSSDSSNSSDSSDSSD 568
Query: 567 KKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEE----EQVKSTDRKS---- 618
+ + + S D + ++D S+ + + S+D KS
Sbjct: 569 SDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSK 628
Query: 619 --AVEAQNEVTENPKQKIAAESSENVDCPE--NPKIKLDGKLDQEGDDVQTAAEEVLADG 674
+ + ++ + +++SS+N D + N D + D ++++ +
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSD 688
Query: 675 DTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESP 734
+ + S + + D + D++ + + S S D+ + S
Sbjct: 689 SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSD 748
Query: 735 SQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRG 794
S + SD+ ++ + S S + + SNS +++D S N ++
Sbjct: 749 SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808
Query: 795 GNEKGKSKE 803
++ S +
Sbjct: 809 SSDSSDSSD 817
Score = 43.5 bits (101), Expect = 8e-04
Identities = 72/560 (12%), Positives = 195/560 (34%), Gaps = 25/560 (4%)
Query: 256 NSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKR 315
NS+ NG + N+ G K + ++ S+ +S+ + +
Sbjct: 523 NSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDS-------- 574
Query: 316 EILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQI 375
N+ + + D+ D D + +++ SS+ + + + + + + S
Sbjct: 575 ----NSSSDSDSSDS--DSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSK 628
Query: 376 LESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQA 435
ES S ++ S+ D + + + SN + D + +++ ++ + +
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSS-DSSNSSNSSDSSDSSDSSDSSSSSDSSNSS 687
Query: 436 GTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVG 495
+ S +S ++ D + ++S +S + + +N + + S++
Sbjct: 688 DSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS 747
Query: 496 RDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKS 555
N + ++ ++ S ++ + + S+ + + D S
Sbjct: 748 DSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSD-SSNSSDSSNS 806
Query: 556 DQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTD 615
++ DSS + N + S + + +D + S+D
Sbjct: 807 SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866
Query: 616 RKSAVEAQN-----EVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEV 670
+ ++ N + +++ + +++SS++ + ++ D + + E
Sbjct: 867 SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES 926
Query: 671 LADGDTLDFED--DTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTL 728
D + D ++ SS D + D++ ++ S+ ++ S D+ +
Sbjct: 927 SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD--SSDSSNSSD 984
Query: 729 PEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPES 788
S S D SD+ ++ ++ S S + + SNS ++ + S +
Sbjct: 985 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSD 1044
Query: 789 REDTRGGNEKGKSKEDCTMS 808
D+ ++ S + S
Sbjct: 1045 SSDSSDSSDSSNSSDSSDSS 1064
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 55.1 bits (131), Expect = 3e-07
Identities = 173/875 (19%), Positives = 342/875 (39%), Gaps = 151/875 (17%)
Query: 18 EAQKLAEARLAAKRAARAEAREIRMKELERQQKEED-----SERYSRRSRRNTSASDEDE 72
E + L + +L A+ AEA E+R++ ++Q+ E+ R R E +
Sbjct: 887 EEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERK 946
Query: 73 RMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEAS 132
+M+ + L +EE+ E+ E+ +R L T ++ + I + + +
Sbjct: 947 KMA---QQMLDLEEQLEE---EEAARQKLQLEKVT------AEAKIKKLEDEILVMDDQN 994
Query: 133 IREIKELNELKDQIQDV---------EGKYMQGLKEMKDSL-AEVEEKYKKAMVSNAQLD 182
+ KE L+++I D+ + K + LK +S+ +E+E + KK S +L+
Sbjct: 995 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELE 1054
Query: 183 NEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALK 242
K + + +L+ Q+AE + Q +K +E + A + L + A+ ALK
Sbjct: 1055 KLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQA---ALARLDDEIAQKNNALK 1111
Query: 243 QREEMLEKH----GIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGR 298
+ E LE H L+SE A + ++G EEL ALK+ + TL
Sbjct: 1112 KIRE-LEGHISDLQEDLDSERAARNKAEKQKRDLG---------EELEALKTELEDTLDS 1161
Query: 299 AS---EVEVKNEIVANVGKREILHNTE---------KEQHTEDTVKDCVDIEVFPAGENT 346
+ E+ K E V K+ + T +++H + + +E F +
Sbjct: 1162 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1221
Query: 347 ED------QKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDR 400
D +K + D A L L A E + + + LE+ QV+ + + +R
Sbjct: 1222 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA--------QVQELQSKCSDGER 1273
Query: 401 TRTPLEPS--NCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMV 458
R L ++++ N E ++ + +++S L + + + + + +
Sbjct: 1274 ARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS-QLQDTQELLQEETRQKL 1332
Query: 459 EVPQEL----------------ETSTGHSLEKEFT--NQEAAEPKE------VPAHSTEV 494
V +L E +LE+ + N + ++ K+ + E
Sbjct: 1333 NVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1392
Query: 495 GRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNE-----PLDMKE 549
G+ ++E E L + K T+ Q+ VD N+ L+ K+
Sbjct: 1393 GKKRFQKEIE--NLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ 1450
Query: 550 PD------EEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLS 603
EEK+ A + + + + ++K+ K +E + K+EL N L
Sbjct: 1451 RKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKML- 1509
Query: 604 EIKEEEQVKSTD-----------RKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKL 652
+ + E+ V S D K A+E Q E + + E + + E+ K++L
Sbjct: 1510 KAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE----ELEDELQATEDAKLRL 1565
Query: 653 DGKL--------------DQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDE 698
+ + D++ ++ + + L + +T + ED+ Q + A ++L E
Sbjct: 1566 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYET-ELEDERKQRALAAAAKKKL-E 1623
Query: 699 GVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQ 758
G KD Q+ A E+A + L + ++ +D E R E+ +
Sbjct: 1624 GDLKDL-----ELQADSAIKGREEAIK-QLRKLQAQMKDFQRELEDARASRDEIFATAKE 1677
Query: 759 TVRKA--LDSNSLE-NDDLSAPGREPGHFNPESRE 790
+KA L+++ ++ +DL+A R + E E
Sbjct: 1678 NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 1712
Score = 36.2 bits (82), Expect = 0.12
Identities = 49/234 (20%), Positives = 93/234 (39%), Gaps = 35/234 (14%)
Query: 33 ARAEAREIRMKELERQQKEEDSERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDF 92
AR E E + ++L+RQ E ++E R +R +A+ + + G L ++
Sbjct: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAK--KKLEGDLKDLELQADSAIKG 1639
Query: 93 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKELNELKDQIQDVEGK 152
E+ + + L A R S D + E NE K + + +
Sbjct: 1640 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKE---------NEKKAKSLEAD-- 1688
Query: 153 YMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQ 212
L ++++ LA E K+A + +L E + + + L+D LE ++A+ +
Sbjct: 1689 ----LMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE 1744
Query: 213 YEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETS 266
EE+ E V++A +Q E+ L++E+AT T+
Sbjct: 1745 LEEEQGNMEAMSD----------RVRKATQQAEQ--------LSNELATERSTA 1780
Score = 35.4 bits (80), Expect = 0.21
Identities = 70/365 (19%), Positives = 145/365 (39%), Gaps = 58/365 (15%)
Query: 5 AAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRN 64
AAA ++++ + + A++ + + A + R+++ + + Q++ ED+ R SR
Sbjct: 1615 AAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA----RASRDE 1670
Query: 65 TSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLAS--LGGTSSRRGSGD 122
A+ ++ S + ++ + + E+ +R L LA S R D
Sbjct: 1671 IFATAKENEKKAKSLEADLMQLQEDLAAAER-ARKQADLEKEELAEELASSLSGRNALQD 1729
Query: 123 TSISIDTEASIREIKELNELKDQIQDVEG------KYMQGLKEMKDSLAEVEEKYKKAMV 176
+ EA I +++E EL+++ ++E K Q +++ + LA +K
Sbjct: 1730 EKRRL--EARIAQLEE--ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1785
Query: 177 SNAQLDNE---------------KTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFE 221
+ QL+ + K+ F + L+ + +LEEQ+ + R+ + K +
Sbjct: 1786 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1845
Query: 222 REKHAHSILQFQFAEVKEALKQREEMLEKHGI---ILNSEIATNGETSDTLNNVGYQGPT 278
++ + Q + ++ +Q +E EK L ++ E S +N
Sbjct: 1846 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRIN----ANRR 1901
Query: 279 KMTKE-------------ELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQ 325
K+ +E E+NALKS L R +E G R ++ N + +
Sbjct: 1902 KLQRELDEATESNEAMGREVNALKS----KLRRGNETSFVPS--RRSGGRRVIENADGSE 1955
Query: 326 HTEDT 330
DT
Sbjct: 1956 EETDT 1960
Score = 31.6 bits (70), Expect = 3.1
Identities = 129/709 (18%), Positives = 246/709 (34%), Gaps = 137/709 (19%)
Query: 15 LSPEAQKLAEARLAAKRAARAEAREIRMKELER--QQKEEDSERYSRRSRRNTSASDEDE 72
LS +KL + A+ A E ++ KE+E QQ EE + Y + + E +
Sbjct: 1373 LSDSKKKLQD--FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430
Query: 73 RMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAA--TLASLGGTSSRRGSGDTSISIDTE 130
+ V ++ EK R L A ++S R +
Sbjct: 1431 DLVVDLDNQRQLVSN-----LEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1485
Query: 131 ASI-REIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFM 189
S+ R ++E E K++++ ++++ S +V + + S L+ +
Sbjct: 1486 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1545
Query: 190 YQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLE 249
Q++ L+D L E+ + +FER+ LQ + + +E +Q + L
Sbjct: 1546 TQLEELEDELQATEDAKLRLEVNMQALKGQFERD------LQARDEQNEEKRRQLQRQLH 1599
Query: 250 KHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL-GRASEVEVKNEI 308
++ L E + K + +L L+ D + GR ++ ++
Sbjct: 1600 EYETELEDERKQRALAA---------AAKKKLEGDLKDLELQADSAIKGREEAIKQLRKL 1650
Query: 309 VANVGKREILHNTEKEQHTEDTVKDCVDIEVF-PAGENTEDQKS--------SEDTAPFL 359
A + ++ E + + D E+F A EN + KS ED A
Sbjct: 1651 QAQM--KDFQRELEDARASRD--------EIFATAKENEKKAKSLEADLMQLQEDLAAAE 1700
Query: 360 GTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNH 419
A E++ ++ L SS N +Q E +
Sbjct: 1701 RARKQADLEKEELAEELASSLSGRNALQDEKRRL-------------------------- 1734
Query: 420 TENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQ 479
EA + Q+EE+ + D+ Q + S + E+ +
Sbjct: 1735 -----EARIAQLEEELEE-------EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQK 1782
Query: 480 EAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVD 539
+ +++ + E+ +E EG +K++ + A E +
Sbjct: 1783 NESARQQLERQNKELRSKLHEMEG---------AVKSKFKSTIAALEAKIAQ-------- 1825
Query: 540 TQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQN 599
++E E+++ ++ A TK+ K+K+KK K E L V+ E
Sbjct: 1826 -------LEEQVEQEAREKQAA-------TKSLKQKDKKLK-----EILLQVEDE----- 1861
Query: 600 TDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQE 659
++E +E+ K R ++ Q E E Q+I A + KL +LD+
Sbjct: 1862 RKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINAN-----------RRKLQRELDEA 1910
Query: 660 GDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKID 708
+ + EV A L ++T R+GG + E + D
Sbjct: 1911 TESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEETD 1959
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 55.1 bits (131), Expect = 3e-07
Identities = 173/875 (19%), Positives = 342/875 (39%), Gaps = 151/875 (17%)
Query: 18 EAQKLAEARLAAKRAARAEAREIRMKELERQQKEED-----SERYSRRSRRNTSASDEDE 72
E + L + +L A+ AEA E+R++ ++Q+ E+ R R E +
Sbjct: 894 EEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERK 953
Query: 73 RMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEAS 132
+M+ + L +EE+ E+ E+ +R L T ++ + I + + +
Sbjct: 954 KMA---QQMLDLEEQLEE---EEAARQKLQLEKVT------AEAKIKKLEDEILVMDDQN 1001
Query: 133 IREIKELNELKDQIQDV---------EGKYMQGLKEMKDSL-AEVEEKYKKAMVSNAQLD 182
+ KE L+++I D+ + K + LK +S+ +E+E + KK S +L+
Sbjct: 1002 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELE 1061
Query: 183 NEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALK 242
K + + +L+ Q+AE + Q +K +E + A + L + A+ ALK
Sbjct: 1062 KLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQA---ALARLDDEIAQKNNALK 1118
Query: 243 QREEMLEKH----GIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGR 298
+ E LE H L+SE A + ++G EEL ALK+ + TL
Sbjct: 1119 KIRE-LEGHISDLQEDLDSERAARNKAEKQKRDLG---------EELEALKTELEDTLDS 1168
Query: 299 AS---EVEVKNEIVANVGKREILHNTE---------KEQHTEDTVKDCVDIEVFPAGENT 346
+ E+ K E V K+ + T +++H + + +E F +
Sbjct: 1169 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1228
Query: 347 ED------QKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDR 400
D +K + D A L L A E + + + LE+ QV+ + + +R
Sbjct: 1229 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA--------QVQELQSKCSDGER 1280
Query: 401 TRTPLEPS--NCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMV 458
R L ++++ N E ++ + +++S L + + + + + +
Sbjct: 1281 ARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS-QLQDTQELLQEETRQKL 1339
Query: 459 EVPQEL----------------ETSTGHSLEKEFT--NQEAAEPKE------VPAHSTEV 494
V +L E +LE+ + N + ++ K+ + E
Sbjct: 1340 NVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1399
Query: 495 GRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNE-----PLDMKE 549
G+ ++E E L + K T+ Q+ VD N+ L+ K+
Sbjct: 1400 GKKRFQKEIE--NLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ 1457
Query: 550 PD------EEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLS 603
EEK+ A + + + + ++K+ K +E + K+EL N L
Sbjct: 1458 RKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKML- 1516
Query: 604 EIKEEEQVKSTD-----------RKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKL 652
+ + E+ V S D K A+E Q E + + E + + E+ K++L
Sbjct: 1517 KAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE----ELEDELQATEDAKLRL 1572
Query: 653 DGKL--------------DQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDE 698
+ + D++ ++ + + L + +T + ED+ Q + A ++L E
Sbjct: 1573 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYET-ELEDERKQRALAAAAKKKL-E 1630
Query: 699 GVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQ 758
G KD Q+ A E+A + L + ++ +D E R E+ +
Sbjct: 1631 GDLKDL-----ELQADSAIKGREEAIK-QLRKLQAQMKDFQRELEDARASRDEIFATAKE 1684
Query: 759 TVRKA--LDSNSLE-NDDLSAPGREPGHFNPESRE 790
+KA L+++ ++ +DL+A R + E E
Sbjct: 1685 NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 1719
Score = 36.2 bits (82), Expect = 0.12
Identities = 49/234 (20%), Positives = 93/234 (39%), Gaps = 35/234 (14%)
Query: 33 ARAEAREIRMKELERQQKEEDSERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDF 92
AR E E + ++L+RQ E ++E R +R +A+ + + G L ++
Sbjct: 1589 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAK--KKLEGDLKDLELQADSAIKG 1646
Query: 93 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKELNELKDQIQDVEGK 152
E+ + + L A R S D + E NE K + + +
Sbjct: 1647 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKE---------NEKKAKSLEAD-- 1695
Query: 153 YMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQ 212
L ++++ LA E K+A + +L E + + + L+D LE ++A+ +
Sbjct: 1696 ----LMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE 1751
Query: 213 YEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETS 266
EE+ E V++A +Q E+ L++E+AT T+
Sbjct: 1752 LEEEQGNMEAMSD----------RVRKATQQAEQ--------LSNELATERSTA 1787
Score = 35.4 bits (80), Expect = 0.21
Identities = 70/365 (19%), Positives = 145/365 (39%), Gaps = 58/365 (15%)
Query: 5 AAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRN 64
AAA ++++ + + A++ + + A + R+++ + + Q++ ED+ R SR
Sbjct: 1622 AAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA----RASRDE 1677
Query: 65 TSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLAS--LGGTSSRRGSGD 122
A+ ++ S + ++ + + E+ +R L LA S R D
Sbjct: 1678 IFATAKENEKKAKSLEADLMQLQEDLAAAER-ARKQADLEKEELAEELASSLSGRNALQD 1736
Query: 123 TSISIDTEASIREIKELNELKDQIQDVEG------KYMQGLKEMKDSLAEVEEKYKKAMV 176
+ EA I +++E EL+++ ++E K Q +++ + LA +K
Sbjct: 1737 EKRRL--EARIAQLEE--ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1792
Query: 177 SNAQLDNE---------------KTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFE 221
+ QL+ + K+ F + L+ + +LEEQ+ + R+ + K +
Sbjct: 1793 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1852
Query: 222 REKHAHSILQFQFAEVKEALKQREEMLEKHGI---ILNSEIATNGETSDTLNNVGYQGPT 278
++ + Q + ++ +Q +E EK L ++ E S +N
Sbjct: 1853 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRIN----ANRR 1908
Query: 279 KMTKE-------------ELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQ 325
K+ +E E+NALKS L R +E G R ++ N + +
Sbjct: 1909 KLQRELDEATESNEAMGREVNALKS----KLRRGNETSFVPS--RRSGGRRVIENADGSE 1962
Query: 326 HTEDT 330
DT
Sbjct: 1963 EETDT 1967
Score = 31.6 bits (70), Expect = 3.1
Identities = 129/709 (18%), Positives = 246/709 (34%), Gaps = 137/709 (19%)
Query: 15 LSPEAQKLAEARLAAKRAARAEAREIRMKELER--QQKEEDSERYSRRSRRNTSASDEDE 72
LS +KL + A+ A E ++ KE+E QQ EE + Y + + E +
Sbjct: 1380 LSDSKKKLQD--FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437
Query: 73 RMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAA--TLASLGGTSSRRGSGDTSISIDTE 130
+ V ++ EK R L A ++S R +
Sbjct: 1438 DLVVDLDNQRQLVSN-----LEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1492
Query: 131 ASI-REIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFM 189
S+ R ++E E K++++ ++++ S +V + + S L+ +
Sbjct: 1493 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1552
Query: 190 YQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLE 249
Q++ L+D L E+ + +FER+ LQ + + +E +Q + L
Sbjct: 1553 TQLEELEDELQATEDAKLRLEVNMQALKGQFERD------LQARDEQNEEKRRQLQRQLH 1606
Query: 250 KHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL-GRASEVEVKNEI 308
++ L E + K + +L L+ D + GR ++ ++
Sbjct: 1607 EYETELEDERKQRALAA---------AAKKKLEGDLKDLELQADSAIKGREEAIKQLRKL 1657
Query: 309 VANVGKREILHNTEKEQHTEDTVKDCVDIEVF-PAGENTEDQKS--------SEDTAPFL 359
A + ++ E + + D E+F A EN + KS ED A
Sbjct: 1658 QAQM--KDFQRELEDARASRD--------EIFATAKENEKKAKSLEADLMQLQEDLAAAE 1707
Query: 360 GTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNH 419
A E++ ++ L SS N +Q E +
Sbjct: 1708 RARKQADLEKEELAEELASSLSGRNALQDEKRRL-------------------------- 1741
Query: 420 TENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQ 479
EA + Q+EE+ + D+ Q + S + E+ +
Sbjct: 1742 -----EARIAQLEEELEE-------EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQK 1789
Query: 480 EAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVD 539
+ +++ + E+ +E EG +K++ + A E +
Sbjct: 1790 NESARQQLERQNKELRSKLHEMEG---------AVKSKFKSTIAALEAKIAQ-------- 1832
Query: 540 TQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQN 599
++E E+++ ++ A TK+ K+K+KK K E L V+ E
Sbjct: 1833 -------LEEQVEQEAREKQAA-------TKSLKQKDKKLK-----EILLQVEDE----- 1868
Query: 600 TDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQE 659
++E +E+ K R ++ Q E E Q+I A + KL +LD+
Sbjct: 1869 RKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINAN-----------RRKLQRELDEA 1917
Query: 660 GDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKID 708
+ + EV A L ++T R+GG + E + D
Sbjct: 1918 TESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEETD 1966
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 55.1 bits (131), Expect = 3e-07
Identities = 173/875 (19%), Positives = 342/875 (39%), Gaps = 151/875 (17%)
Query: 18 EAQKLAEARLAAKRAARAEAREIRMKELERQQKEED-----SERYSRRSRRNTSASDEDE 72
E + L + +L A+ AEA E+R++ ++Q+ E+ R R E +
Sbjct: 894 EEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERK 953
Query: 73 RMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEAS 132
+M+ + L +EE+ E+ E+ +R L T ++ + I + + +
Sbjct: 954 KMA---QQMLDLEEQLEE---EEAARQKLQLEKVT------AEAKIKKLEDEILVMDDQN 1001
Query: 133 IREIKELNELKDQIQDV---------EGKYMQGLKEMKDSL-AEVEEKYKKAMVSNAQLD 182
+ KE L+++I D+ + K + LK +S+ +E+E + KK S +L+
Sbjct: 1002 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELE 1061
Query: 183 NEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALK 242
K + + +L+ Q+AE + Q +K +E + A + L + A+ ALK
Sbjct: 1062 KLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQA---ALARLDDEIAQKNNALK 1118
Query: 243 QREEMLEKH----GIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGR 298
+ E LE H L+SE A + ++G EEL ALK+ + TL
Sbjct: 1119 KIRE-LEGHISDLQEDLDSERAARNKAEKQKRDLG---------EELEALKTELEDTLDS 1168
Query: 299 AS---EVEVKNEIVANVGKREILHNTE---------KEQHTEDTVKDCVDIEVFPAGENT 346
+ E+ K E V K+ + T +++H + + +E F +
Sbjct: 1169 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1228
Query: 347 ED------QKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDR 400
D +K + D A L L A E + + + LE+ QV+ + + +R
Sbjct: 1229 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA--------QVQELQSKCSDGER 1280
Query: 401 TRTPLEPS--NCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMV 458
R L ++++ N E ++ + +++S L + + + + + +
Sbjct: 1281 ARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS-QLQDTQELLQEETRQKL 1339
Query: 459 EVPQEL----------------ETSTGHSLEKEFT--NQEAAEPKE------VPAHSTEV 494
V +L E +LE+ + N + ++ K+ + E
Sbjct: 1340 NVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1399
Query: 495 GRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNE-----PLDMKE 549
G+ ++E E L + K T+ Q+ VD N+ L+ K+
Sbjct: 1400 GKKRFQKEIE--NLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ 1457
Query: 550 PD------EEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLS 603
EEK+ A + + + + ++K+ K +E + K+EL N L
Sbjct: 1458 RKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKML- 1516
Query: 604 EIKEEEQVKSTD-----------RKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKL 652
+ + E+ V S D K A+E Q E + + E + + E+ K++L
Sbjct: 1517 KAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE----ELEDELQATEDAKLRL 1572
Query: 653 DGKL--------------DQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDE 698
+ + D++ ++ + + L + +T + ED+ Q + A ++L E
Sbjct: 1573 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYET-ELEDERKQRALAAAAKKKL-E 1630
Query: 699 GVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQ 758
G KD Q+ A E+A + L + ++ +D E R E+ +
Sbjct: 1631 GDLKDL-----ELQADSAIKGREEAIK-QLRKLQAQMKDFQRELEDARASRDEIFATAKE 1684
Query: 759 TVRKA--LDSNSLE-NDDLSAPGREPGHFNPESRE 790
+KA L+++ ++ +DL+A R + E E
Sbjct: 1685 NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 1719
Score = 36.2 bits (82), Expect = 0.12
Identities = 49/234 (20%), Positives = 93/234 (39%), Gaps = 35/234 (14%)
Query: 33 ARAEAREIRMKELERQQKEEDSERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDF 92
AR E E + ++L+RQ E ++E R +R +A+ + + G L ++
Sbjct: 1589 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAK--KKLEGDLKDLELQADSAIKG 1646
Query: 93 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKELNELKDQIQDVEGK 152
E+ + + L A R S D + E NE K + + +
Sbjct: 1647 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKE---------NEKKAKSLEAD-- 1695
Query: 153 YMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQ 212
L ++++ LA E K+A + +L E + + + L+D LE ++A+ +
Sbjct: 1696 ----LMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE 1751
Query: 213 YEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETS 266
EE+ E V++A +Q E+ L++E+AT T+
Sbjct: 1752 LEEEQGNMEAMSD----------RVRKATQQAEQ--------LSNELATERSTA 1787
Score = 34.7 bits (78), Expect = 0.36
Identities = 50/269 (18%), Positives = 114/269 (42%), Gaps = 32/269 (11%)
Query: 5 AAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRN 64
AAA ++++ + + A++ + + A + R+++ + + Q++ ED+ R SR
Sbjct: 1622 AAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA----RASRDE 1677
Query: 65 TSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLAS--LGGTSSRRGSGD 122
A+ ++ S + ++ + + E+ +R L LA S R D
Sbjct: 1678 IFATAKENEKKAKSLEADLMQLQEDLAAAER-ARKQADLEKEELAEELASSLSGRNALQD 1736
Query: 123 TSISIDTEASIREIKELNELKDQIQDVEG------KYMQGLKEMKDSLAEVEEKYKKAMV 176
+ EA I +++E EL+++ ++E K Q +++ + LA +K
Sbjct: 1737 EKRRL--EARIAQLEE--ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1792
Query: 177 SNAQLDNE---------------KTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFE 221
+ QL+ + K+ F + L+ + +LEEQ+ + R+ + K +
Sbjct: 1793 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1852
Query: 222 REKHAHSILQFQFAEVKEALKQREEMLEK 250
++ + Q + ++ +Q +E EK
Sbjct: 1853 QKDKKLKEILLQVEDERKMAEQYKEQAEK 1881
Score = 32.3 bits (72), Expect = 1.8
Identities = 120/573 (20%), Positives = 219/573 (38%), Gaps = 78/573 (13%)
Query: 15 LSPEAQKLAEARLAAKRAARAEAREIRMKELER--QQKEEDSERYSRRSRRNTSASDEDE 72
LS +KL + A+ A E ++ KE+E QQ EE + Y + + E +
Sbjct: 1380 LSDSKKKLQD--FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437
Query: 73 RMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAA--TLASLGGTSSRRGSGDTSISIDTE 130
+ V ++ EK R L A ++S R +
Sbjct: 1438 DLVVDLDNQRQLVSN-----LEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1492
Query: 131 ASI-REIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFM 189
S+ R ++E E K++++ ++++ S +V + + S L+ +
Sbjct: 1493 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1552
Query: 190 YQVDTLKDMLL------------------ELEEQLAESRRQYEEKNKEFEREKHAHSI-- 229
Q++ L+D L + E L Q EEK ++ +R+ H +
Sbjct: 1553 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1612
Query: 230 --LQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNA 287
+ Q A A K+ E L+ + +S I E L + Q K + EL
Sbjct: 1613 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKL--QAQMKDFQRELED 1670
Query: 288 LKSTGDGTLGRASEVEVK-NEIVANVGK-REILHNTEKEQHTEDTVKDCVDIEVFP--AG 343
+++ D A E E K + A++ + +E L E+ + D K+ + E+ +G
Sbjct: 1671 ARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG 1730
Query: 344 ENT-EDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVE--SNEV-----MG 395
N +D+K + + L EEQ + + S + + T Q E SNE+
Sbjct: 1731 RNALQDEKRRLEAR--IAQLEEELEEEQGNMEAM-SDRVRKATQQAEQLSNELATERSTA 1787
Query: 396 APDDRTRTPLEPSN-----CWSDLDGG-----NHTENVGEAAVTQVEEQA------GTVA 439
++ R LE N +++G T EA + Q+EEQ A
Sbjct: 1788 QKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAA 1847
Query: 440 SCPLGHSDDTV------YHDDKCMVEVPQELETSTGHSLEKEFTNQ--EAAEPKE-VPAH 490
+ L D + D++ M E +E + G++ K+ Q EA E + + A+
Sbjct: 1848 TKSLKQKDKKLKEILLQVEDERKMAEQYKE-QAEKGNARVKQLKRQLEEAEEESQRINAN 1906
Query: 491 STEVGRDHNE-EEGEETGLRDEKPIKTEVPGSP 522
++ R+ +E E E R+ +K+++ G P
Sbjct: 1907 RRKLQRELDEATESNEAMGREVNALKSKLRGPP 1939
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 55.1 bits (131), Expect = 3e-07
Identities = 173/875 (19%), Positives = 342/875 (39%), Gaps = 151/875 (17%)
Query: 18 EAQKLAEARLAAKRAARAEAREIRMKELERQQKEED-----SERYSRRSRRNTSASDEDE 72
E + L + +L A+ AEA E+R++ ++Q+ E+ R R E +
Sbjct: 887 EEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERK 946
Query: 73 RMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEAS 132
+M+ + L +EE+ E+ E+ +R L T ++ + I + + +
Sbjct: 947 KMA---QQMLDLEEQLEE---EEAARQKLQLEKVT------AEAKIKKLEDEILVMDDQN 994
Query: 133 IREIKELNELKDQIQDV---------EGKYMQGLKEMKDSL-AEVEEKYKKAMVSNAQLD 182
+ KE L+++I D+ + K + LK +S+ +E+E + KK S +L+
Sbjct: 995 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELE 1054
Query: 183 NEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALK 242
K + + +L+ Q+AE + Q +K +E + A + L + A+ ALK
Sbjct: 1055 KLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQA---ALARLDDEIAQKNNALK 1111
Query: 243 QREEMLEKH----GIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGR 298
+ E LE H L+SE A + ++G EEL ALK+ + TL
Sbjct: 1112 KIRE-LEGHISDLQEDLDSERAARNKAEKQKRDLG---------EELEALKTELEDTLDS 1161
Query: 299 AS---EVEVKNEIVANVGKREILHNTE---------KEQHTEDTVKDCVDIEVFPAGENT 346
+ E+ K E V K+ + T +++H + + +E F +
Sbjct: 1162 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1221
Query: 347 ED------QKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDR 400
D +K + D A L L A E + + + LE+ QV+ + + +R
Sbjct: 1222 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA--------QVQELQSKCSDGER 1273
Query: 401 TRTPLEPS--NCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMV 458
R L ++++ N E ++ + +++S L + + + + + +
Sbjct: 1274 ARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS-QLQDTQELLQEETRQKL 1332
Query: 459 EVPQEL----------------ETSTGHSLEKEFT--NQEAAEPKE------VPAHSTEV 494
V +L E +LE+ + N + ++ K+ + E
Sbjct: 1333 NVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1392
Query: 495 GRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNE-----PLDMKE 549
G+ ++E E L + K T+ Q+ VD N+ L+ K+
Sbjct: 1393 GKKRFQKEIE--NLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ 1450
Query: 550 PD------EEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLS 603
EEK+ A + + + + ++K+ K +E + K+EL N L
Sbjct: 1451 RKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKML- 1509
Query: 604 EIKEEEQVKSTD-----------RKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKL 652
+ + E+ V S D K A+E Q E + + E + + E+ K++L
Sbjct: 1510 KAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE----ELEDELQATEDAKLRL 1565
Query: 653 DGKL--------------DQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDE 698
+ + D++ ++ + + L + +T + ED+ Q + A ++L E
Sbjct: 1566 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYET-ELEDERKQRALAAAAKKKL-E 1623
Query: 699 GVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQ 758
G KD Q+ A E+A + L + ++ +D E R E+ +
Sbjct: 1624 GDLKDL-----ELQADSAIKGREEAIK-QLRKLQAQMKDFQRELEDARASRDEIFATAKE 1677
Query: 759 TVRKA--LDSNSLE-NDDLSAPGREPGHFNPESRE 790
+KA L+++ ++ +DL+A R + E E
Sbjct: 1678 NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 1712
Score = 36.2 bits (82), Expect = 0.12
Identities = 49/234 (20%), Positives = 93/234 (39%), Gaps = 35/234 (14%)
Query: 33 ARAEAREIRMKELERQQKEEDSERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDF 92
AR E E + ++L+RQ E ++E R +R +A+ + + G L ++
Sbjct: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAK--KKLEGDLKDLELQADSAIKG 1639
Query: 93 TEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKELNELKDQIQDVEGK 152
E+ + + L A R S D + E NE K + + +
Sbjct: 1640 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKE---------NEKKAKSLEAD-- 1688
Query: 153 YMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQ 212
L ++++ LA E K+A + +L E + + + L+D LE ++A+ +
Sbjct: 1689 ----LMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE 1744
Query: 213 YEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETS 266
EE+ E V++A +Q E+ L++E+AT T+
Sbjct: 1745 LEEEQGNMEAMSD----------RVRKATQQAEQ--------LSNELATERSTA 1780
Score = 34.7 bits (78), Expect = 0.36
Identities = 50/269 (18%), Positives = 114/269 (42%), Gaps = 32/269 (11%)
Query: 5 AAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRN 64
AAA ++++ + + A++ + + A + R+++ + + Q++ ED+ R SR
Sbjct: 1615 AAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA----RASRDE 1670
Query: 65 TSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLAS--LGGTSSRRGSGD 122
A+ ++ S + ++ + + E+ +R L LA S R D
Sbjct: 1671 IFATAKENEKKAKSLEADLMQLQEDLAAAER-ARKQADLEKEELAEELASSLSGRNALQD 1729
Query: 123 TSISIDTEASIREIKELNELKDQIQDVEG------KYMQGLKEMKDSLAEVEEKYKKAMV 176
+ EA I +++E EL+++ ++E K Q +++ + LA +K
Sbjct: 1730 EKRRL--EARIAQLEE--ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1785
Query: 177 SNAQLDNE---------------KTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFE 221
+ QL+ + K+ F + L+ + +LEEQ+ + R+ + K +
Sbjct: 1786 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1845
Query: 222 REKHAHSILQFQFAEVKEALKQREEMLEK 250
++ + Q + ++ +Q +E EK
Sbjct: 1846 QKDKKLKEILLQVEDERKMAEQYKEQAEK 1874
Score = 32.3 bits (72), Expect = 1.8
Identities = 120/573 (20%), Positives = 219/573 (38%), Gaps = 78/573 (13%)
Query: 15 LSPEAQKLAEARLAAKRAARAEAREIRMKELER--QQKEEDSERYSRRSRRNTSASDEDE 72
LS +KL + A+ A E ++ KE+E QQ EE + Y + + E +
Sbjct: 1373 LSDSKKKLQD--FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430
Query: 73 RMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAA--TLASLGGTSSRRGSGDTSISIDTE 130
+ V ++ EK R L A ++S R +
Sbjct: 1431 DLVVDLDNQRQLVSN-----LEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1485
Query: 131 ASI-REIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFM 189
S+ R ++E E K++++ ++++ S +V + + S L+ +
Sbjct: 1486 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1545
Query: 190 YQVDTLKDMLL------------------ELEEQLAESRRQYEEKNKEFEREKHAHSI-- 229
Q++ L+D L + E L Q EEK ++ +R+ H +
Sbjct: 1546 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1605
Query: 230 --LQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNA 287
+ Q A A K+ E L+ + +S I E L + Q K + EL
Sbjct: 1606 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKL--QAQMKDFQRELED 1663
Query: 288 LKSTGDGTLGRASEVEVK-NEIVANVGK-REILHNTEKEQHTEDTVKDCVDIEVFP--AG 343
+++ D A E E K + A++ + +E L E+ + D K+ + E+ +G
Sbjct: 1664 ARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG 1723
Query: 344 ENT-EDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVE--SNEV-----MG 395
N +D+K + + L EEQ + + S + + T Q E SNE+
Sbjct: 1724 RNALQDEKRRLEAR--IAQLEEELEEEQGNMEAM-SDRVRKATQQAEQLSNELATERSTA 1780
Query: 396 APDDRTRTPLEPSN-----CWSDLDGG-----NHTENVGEAAVTQVEEQA------GTVA 439
++ R LE N +++G T EA + Q+EEQ A
Sbjct: 1781 QKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAA 1840
Query: 440 SCPLGHSDDTV------YHDDKCMVEVPQELETSTGHSLEKEFTNQ--EAAEPKE-VPAH 490
+ L D + D++ M E +E + G++ K+ Q EA E + + A+
Sbjct: 1841 TKSLKQKDKKLKEILLQVEDERKMAEQYKE-QAEKGNARVKQLKRQLEEAEEESQRINAN 1899
Query: 491 STEVGRDHNE-EEGEETGLRDEKPIKTEVPGSP 522
++ R+ +E E E R+ +K+++ G P
Sbjct: 1900 RRKLQRELDEATESNEAMGREVNALKSKLRGPP 1932
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 55.1 bits (131), Expect = 3e-07
Identities = 148/763 (19%), Positives = 279/763 (36%), Gaps = 119/763 (15%)
Query: 10 REIDCLSPEAQKLAEARLAAKR-------AARAEAREIRMKELERQQKEEDSERYSRRSR 62
RE+ E +L R+A +R AAR R R + L ++Q+EE + + +
Sbjct: 8 RELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVE 67
Query: 63 RNTSASDEDERMSVGSRGS--------------LRVEERPEKDFTEKGSRNMPGLSAATL 108
N S DE + + R EER +K E R T
Sbjct: 68 VNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITD 127
Query: 109 ASLGGTSSRRGSGDTSISIDTEASIR--------EIKELNELKDQIQDVEGKYMQ-GLKE 159
ASL SRR DT+ + TE + EI+E + Q + + + KE
Sbjct: 128 ASLS-LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKE 186
Query: 160 MKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKE 219
K+ E EEK K+ + Q++ M + T + + L + EE +E
Sbjct: 187 DKEKEEEEEEKPKRGSIGENQVE-----VMVEEKTTESQEETVVMSLKNGQISSEEPKQE 241
Query: 220 FEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTK 279
ERE+ + I + +++E K+R E +
Sbjct: 242 EEREQGSDEISHHE--KMEEEDKERAEAER----------------------------AR 271
Query: 280 MTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEV 339
+ EE +K+ D + ++ E A +RE E+E+ E+ + + +
Sbjct: 272 LEAEERERIKAEQDKKIAD-ERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQR 330
Query: 340 FPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDD 399
E+++++E+ A E Q + + ++ + E E +
Sbjct: 331 I----KEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQ 386
Query: 400 RTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVE 459
+ LE T+ GE ++E + ++ +DK
Sbjct: 387 KRNKQLEEKK-----HAMQETKIKGEKVEQKIEGK----------WVNEKKAQEDKLQTA 431
Query: 460 V--PQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTE 517
V Q E T ++E ++ K+ ++ +D +E E D K TE
Sbjct: 432 VLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKE-EVKSFMDRKKGFTE 490
Query: 518 VPGSPAG--------TEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKK- 568
V TE G ++VDT KE + + G+ L+ +++
Sbjct: 491 VKSQNGEFMTHKLKHTENTFSRPGGRASVDT-------KEAEGAPQVEAGKRLEELRRRR 543
Query: 569 --TKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEV 626
T++++ + K+K L+++KK+ + L E ++ + + DRK E +
Sbjct: 544 GETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRR 603
Query: 627 TENPKQKIAAESSENVDCPENPKIKLDGKLDQEGD-DVQTAAEEVLADGDTLDFEDDTVQ 685
+ ++ AE++E + K+ DG D + T L + +F + +VQ
Sbjct: 604 LKEEIERRRAEAAE-----KRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQ 658
Query: 686 -SSGPRAGGE-----ELDEGVAKDNAKIDGATQSSPAEPKSED 722
SSG ++ + ++D + + + I+G + P +P + D
Sbjct: 659 KSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASD 701
Score = 40.4 bits (93), Expect = 0.007
Identities = 89/511 (17%), Positives = 186/511 (36%), Gaps = 59/511 (11%)
Query: 208 ESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSD 267
E RR+ + +E R + Q + +EA ++R + + E + G+ +D
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTD 64
Query: 268 TLN-NVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQH 326
+ N P + K + GD + + E ++ + E+++
Sbjct: 65 QVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREER----RQKRLQEALERQKE 120
Query: 327 TEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTV 386
+ T+ D A + ++ DTA E ++ E S +
Sbjct: 121 FDPTITD--------ASLSLPSRRMQNDTA------------ENETTEKEEKSESRQERY 160
Query: 387 QVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHS 446
++E E T T N W D + + E EE+ +G +
Sbjct: 161 EIEETE--------TVTKSYQKNDWRDAEENKKEDKEKE------EEEEEKPKRGSIGEN 206
Query: 447 DDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEET 506
V ++K + ET + +++E + +E S E+ EE ++
Sbjct: 207 QVEVMVEEKT---TESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKE 263
Query: 507 GLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQ 566
E+ E + + A + ++ + + + E + ++ E + +
Sbjct: 264 RAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQER--ERREAEERERMREEE 321
Query: 567 KKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEV 626
K+ ++++ K+++ E + +K+E + IKEEE+ + +R+ A + E
Sbjct: 322 KRAAEERQRIKEEEKRAAEERQR-IKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEK 380
Query: 627 TENPKQKIAAESSENVDCPENPKI-------KLDGKLDQE----GDDVQTAAEEVLAD-- 673
+ +QK + E + KI K++GK E D +QTA + +
Sbjct: 381 AKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEK 440
Query: 674 GDTLDFEDDTVQSSGPRAGGEEL-DEGVAKD 703
G + + + +Q P EE+ DE + KD
Sbjct: 441 GTKVQAKREKLQEDKPTFKKEEIKDEKIKKD 471
Score = 33.9 bits (76), Expect = 0.62
Identities = 54/234 (23%), Positives = 92/234 (39%), Gaps = 56/234 (23%)
Query: 5 AAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEED---SERYSRRS 61
AAAQ RE EA++ R KRAA +E +R ++EE ER +
Sbjct: 301 AAAQERE----RREAEERERMREEEKRAA---------EERQRIKEEEKRAAEERQRIKE 347
Query: 62 RRNTSASD-----EDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSS 116
+A + E+E+ + R R EE EK E+ RN
Sbjct: 348 EEKRAAEERQRIKEEEKRAAEERQRARAEEE-EKAKVEEQKRNKQ--------------- 391
Query: 117 RRGSGDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSL------AEVEEK 170
+ + +++E K E + Q +EGK++ K +D L + EEK
Sbjct: 392 ---------LEEKKHAMQETKIKGEKVE--QKIEGKWVNEKKAQEDKLQTAVLKKQGEEK 440
Query: 171 YKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREK 224
K +L +K F + + +KD ++ +++ E + + ++ K F K
Sbjct: 441 GTKVQAKREKLQEDKPTF--KKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVK 492
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 54.7 bits (130), Expect = 3e-07
Identities = 73/309 (23%), Positives = 124/309 (40%), Gaps = 51/309 (16%)
Query: 453 DDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEV-----PAHSTE--VGRDHNEEEGEE 505
+ C E +++E G E T AA+ E+ PA T+ G+ NE E
Sbjct: 8 ESDCSAEAREKMEQKEGKLSEDGTTVSPAADNPEMSGGGAPAEETKGTAGKAINEGPPTE 67
Query: 506 TGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSS 565
+G +++ P + G A +G EA G DE K + Q EA
Sbjct: 68 SGKQEKAPAED---GMSAELQG---EANGL---------------DEVKVESQREAGGKE 106
Query: 566 QKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNE 625
+ + KK+ +K+++ V + + K+E SE KE E+ +ST + ++ +
Sbjct: 107 DAEAELKKEDGEKEETTVGSQEMTGRKEETK------SEPKEAEEKEST-----LASEKQ 155
Query: 626 VTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQ 685
E + K ES + D N + K + K E +D +TA++E G + + +
Sbjct: 156 KAEEKEAK--PESGQKADA--NDRDKPEPKATVEEEDAKTASQE--ETGQRKECSTEPKE 209
Query: 686 SSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAE 745
+ E + V +D AK + P EP ++ + E ++ DA EAE
Sbjct: 210 KATDEEAKAESQKAVVEDEAKAE------PKEPDGKEEAKHGAKEEADAKEEAEDAEEAE 263
Query: 746 STERCEMSE 754
E E
Sbjct: 264 PGSPSEEQE 272
Score = 52.4 bits (124), Expect = 2e-06
Identities = 67/297 (22%), Positives = 115/297 (38%), Gaps = 26/297 (8%)
Query: 461 PQELETSTGHSLEKEFTNQEAAEPKEVPAH---STEVGRDHN-------EEEGEETGLRD 510
P E T E E+ + ++ PA S E+ + N E + E G D
Sbjct: 48 PAEETKGTAGKAINEGPPTESGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKED 107
Query: 511 EKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTK 570
+ + G T QE TG +T++EP + +E + + ++ +A + K
Sbjct: 108 AEAELKKEDGEKEETTVGSQEMTGRKE-ETKSEPKEAEEKESTLASEKQKAEEKEAKPES 166
Query: 571 NKKKKNKKKKSPVPVETLK--DVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTE 628
+K + P P T++ D K + E E + K+TD ++ E+Q V E
Sbjct: 167 GQKADANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVE 226
Query: 629 NPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQSSG 688
+ + E + K + D K +E +D + A ++ D E + +G
Sbjct: 227 DEAKAEPKEPDGKEEAKHGAKEEADAK--EEAEDAEEAEPGSPSEEQEQDVEKEPEGGAG 284
Query: 689 P-RAGGEELDEGVAKD--NAKIDG-------ATQSSPAEPKSEDADRCTLPEHESPS 735
+ EE E + N DG + Q+SP+ +S +D P ESPS
Sbjct: 285 VIPSSPEEWPESPTGEGHNLSTDGLGPDCVASGQTSPSASESSPSDVPQSPP-ESPS 340
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 53.9 bits (128), Expect = 6e-07
Identities = 139/701 (19%), Positives = 265/701 (37%), Gaps = 64/701 (9%)
Query: 44 ELERQQKEEDSERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGL 103
+L++ KE D E RR+ +T + E E+M + R+ E K E R
Sbjct: 459 KLDKIMKELDEEGNQRRNLESTVSQIEKEKMLL----QHRINEYQRKAEQENEKRRNVEN 514
Query: 104 SAATLASLGGTSSRRGSGDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDS 163
+TL + + ++++E N+L D + + EM S
Sbjct: 515 EVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKS 574
Query: 164 LAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFERE 223
++++E ++ N L+N K+ T KD +L+ L RR ++
Sbjct: 575 ISQLESLNRELQERNRILENSKS------QTDKD-YYQLQAILEAERRDRGHDSEMIGDL 627
Query: 224 KHAHSILQFQFAEVKEALKQRE-EMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTK 282
+ + LQ + +K L++ E E E ++ +SE N D N + + +
Sbjct: 628 QARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDL--NYKLKSLQQRLE 685
Query: 283 EELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTV----KDC--VD 336
+E+N K T + +E + ++++ E + E+ V K C +D
Sbjct: 686 QEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLD 745
Query: 337 IEVFPAGENTE----DQKSSEDTAPFL------GTLAGATYEEQVQSQILESSSLP--EN 384
+++ + + E +++ ED L + + ++++Q E+ +L E
Sbjct: 746 VDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEK 805
Query: 385 TVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLG 444
++ E N ++ A + E + G N G+ Q + +A S
Sbjct: 806 QMKQEINTLLEA---KRLLEFELAQLTKQYRG-----NEGQMRELQDQLEAEQYFS---- 853
Query: 445 HSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGE 504
T+Y + E+ +E+E +L+K QE KE A ++ E E
Sbjct: 854 ----TLYKTQ--VKELKEEIEEKNRENLKK---IQELQNEKETLATQLDLAETKAESEQL 904
Query: 505 ETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDS 564
GL +E+ + A + + TV E M D E ++ E L
Sbjct: 905 ARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTE 964
Query: 565 SQKKTKNKKKKNKKKK-SPVPVETLKDVKKELTYQN---TDLSEIKEEEQVKSTDRKSAV 620
KK + + K K+++ S + K++ E T + L+EI + K DRK A
Sbjct: 965 KMKKAEEEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFK-IDRKKAN 1023
Query: 621 EAQNEVTENPKQKIAAESSENVDCPENPKI-KLDGKLDQEGDDVQTAAEEVLADGDTLDF 679
E +K+ E ++ E K ++ K +E +D+Q E A + L
Sbjct: 1024 TQDLRKKEKENRKLQLELNQ-----EREKFNQMVVKHQKELNDMQAQLVEECAHRNELQM 1078
Query: 680 EDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKS 720
+ + +S + + LD + A A ++ P+S
Sbjct: 1079 QLASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPES 1119
Score = 48.5 bits (114), Expect = 2e-05
Identities = 66/306 (21%), Positives = 127/306 (41%), Gaps = 19/306 (6%)
Query: 21 KLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRNTSASDEDERMSVGSRG 80
K+ +ARL K + EA+ + M E+E++ KEE R + R + + V
Sbjct: 692 KVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAR-EKAENRVVQIEKQCSMLDV---- 746
Query: 81 SLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKELN 140
L+ ++ + T R + TL L S++R + + + E L
Sbjct: 747 DLKQSQQKLEHLTGNKERMEDEVKNLTL-QLEQESNKR----LLLQNELKTQAFEADNLK 801
Query: 141 ELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLL 200
L+ Q++ ++ + ++ LA++ ++Y+ +L ++ Y K +
Sbjct: 802 GLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVK 861
Query: 201 ELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVK-EALKQREEMLEKHGIILNSEI 259
EL+E++ E R+ +K +E + EK + Q AE K E+ + +LE+ L E
Sbjct: 862 ELKEEIEEKNRENLKKIQELQNEKETLA-TQLDLAETKAESEQLARGLLEEQYFELTQE- 919
Query: 260 ATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILH 319
+ S + + T EE N++ + L R +E E+ + K E +
Sbjct: 920 -SKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENE-----ELTEKMKKAEEEY 973
Query: 320 NTEKEQ 325
EKE+
Sbjct: 974 KLEKEE 979
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 53.1 bits (126), Expect = 1e-06
Identities = 59/252 (23%), Positives = 109/252 (43%), Gaps = 21/252 (8%)
Query: 457 MVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKT 516
+V V E++ S K T + E + + + V E EE + K +
Sbjct: 27 LVPVTPEVKPKRTSSSRKMKTKSDMME-ENIDTSAQAVAETKQEAVVEEDYNENAKNGEA 85
Query: 517 EVPGSPAGT-------EGNCQEATGPS-------TVDTQNEPLDMKEPDEEKSDQQGEA- 561
++ +PA E N ++AT + +NE D KE +E++++++GEA
Sbjct: 86 KITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAG 145
Query: 562 -LDSSQK-KTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSA 619
D +K + K+ KN +K E K E N + + K E++ + DRK
Sbjct: 146 KEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKET 205
Query: 620 VEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAE-EVLADGDTLD 678
+ + E+ K+K + ++V E+ K + DGK D+ G++ + E E L + +
Sbjct: 206 GDGKE--NEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGK 263
Query: 679 FEDDTVQSSGPR 690
ED+ + G +
Sbjct: 264 EEDEIKEDDGKK 275
Score = 37.4 bits (85), Expect = 0.056
Identities = 35/161 (21%), Positives = 64/161 (39%), Gaps = 7/161 (4%)
Query: 18 EAQKLAEARLAAKRAARAEAREIRMKELERQ-----QKEEDSERYSRRSRRNTSASDEDE 72
E K EA++ A+ E E++ + +E +K+E + + +ED+
Sbjct: 78 ENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQ 137
Query: 73 RMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEAS 132
G G +E+ E+D E + N G A G G G+ +
Sbjct: 138 NEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKED--GKKGEDGKGNGEDGKEKGED 195
Query: 133 IREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKK 173
+E ++ E D ++ +GK KE KD + +EK ++
Sbjct: 196 EKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKERE 236
Score = 34.3 bits (77), Expect = 0.47
Identities = 36/196 (18%), Positives = 79/196 (40%), Gaps = 19/196 (9%)
Query: 617 KSAVEAQNEVTENPKQKIAAESSENVDCPENPKIK---------LDGKLDQEGDDVQTAA 667
K Q ++ + PK++ A S+ V P P++K + K D +++ T+A
Sbjct: 3 KRKAAGQGDMRQEPKRRSARLSAMLV--PVTPEVKPKRTSSSRKMKTKSDMMEENIDTSA 60
Query: 668 EEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCT 727
+ V E+D +++ + G ++ E A + ++ E EDA
Sbjct: 61 QAVAETKQEAVVEEDYNENA--KNGEAKITEAPASEKEIVE------VKEENIEDATEKG 112
Query: 728 LPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPE 787
+ E+ + ++ + E + + + +E + ++ D E+ G E G E
Sbjct: 113 GEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKE 172
Query: 788 SREDTRGGNEKGKSKE 803
+ +G + KG ++
Sbjct: 173 KEDGKKGEDGKGNGED 188
Score = 32.7 bits (73), Expect = 1.4
Identities = 53/239 (22%), Positives = 94/239 (39%), Gaps = 35/239 (14%)
Query: 535 PSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQK---KTK---------NKKKKNKKKK-- 580
P T + + + + KSD E +D+S + +TK N+ KN + K
Sbjct: 29 PVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKIT 88
Query: 581 -SPVPVETLKDVKKELTYQNTD---------LSEIK-EEEQVKSTD---RKSAVEAQNEV 626
+P + + +VK+E T+ +E+K EEE K + + EA E
Sbjct: 89 EAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKED 148
Query: 627 TENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQS 686
+ ++ E + E+ K K DGK +G+D + E+ G+ E+D ++
Sbjct: 149 KDEKGEEDGKEDKNGNEKGEDAKEKEDGK---KGEDGKGNGEDGKEKGEDEKEEEDRKET 205
Query: 687 SGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAE 745
G+E ++G K + K + E + ED E ++ D E E
Sbjct: 206 ----GDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEE 260
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 52.8 bits (125), Expect = 1e-06
Identities = 114/580 (19%), Positives = 212/580 (36%), Gaps = 108/580 (18%)
Query: 131 ASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAE---VEEKYKKAMVSNAQLDNEKTN 187
AS E KEL EL+D+ + + + + LK+ +D E ++ K + N L +
Sbjct: 270 ASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLRE 329
Query: 188 FMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHA-----------HSILQFQFAE 236
F + L+D L EL E+ +++ +++ EK + E+E A + ILQ + ++
Sbjct: 330 FASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQ 389
Query: 237 VKEALKQ-----REEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKST 291
++E L Q +E E G +L E + NN Q +M + E
Sbjct: 390 LEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERG----- 444
Query: 292 GDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKS 351
+ + +++A G H E++Q + D + + N K
Sbjct: 445 -----------QQEAKLLAERG-----HFEEEKQQLSSLITD-----LQSSISNLSQAKE 483
Query: 352 SEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCW 411
+ A GA QV S E ++L T+Q + E+ G
Sbjct: 484 ELEQA---SQAHGARLTAQVASLTSELTTL-NATIQQQDQELAGLKQQAKE--------- 530
Query: 412 SDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHS 471
+ A Q +EQA + ++ ++ + EV +
Sbjct: 531 ---------KQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAE--------- 572
Query: 472 LEKEFTNQEAAEPKEVPAHSTEVG-RDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQ 530
++E T Q+ A+ A E R+ + + L EK K E+ +
Sbjct: 573 -KQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEAR 631
Query: 531 EATGPSTVDTQNEPLDMKEPDEE-------KSDQQGEA----------LDSSQKKTKNKK 573
++ S Q E ++ EE +Q EA L S Q+K K+
Sbjct: 632 DSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKE 691
Query: 574 KKNKKK-----KSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTE 628
+ ++K + E+LK K L + ++ EE+Q ++ K+ + E +
Sbjct: 692 RVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHK 751
Query: 629 NPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAE 668
++++ E + + L+ +L Q G+ Q E
Sbjct: 752 RERKELEEERA--------GRKGLEARLQQLGEAHQAETE 783
Score = 42.7 bits (99), Expect = 0.001
Identities = 73/336 (21%), Positives = 135/336 (40%), Gaps = 37/336 (11%)
Query: 8 QSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRNTSA 67
Q RE+ L+ E + A+A LA ++AARAE E+R++ +Q+ E + + T
Sbjct: 1002 QEREVARLTQERGR-AQADLALEKAARAEL-EMRLQNALNEQRVEFATLQEALAHALTEK 1059
Query: 68 SDEDERMS-VGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSIS 126
+D+ ++ + + +++E E T K + AS G S
Sbjct: 1060 EGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTG 1119
Query: 127 IDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAE-----------VEEKYKKAM 175
EA E+ +L + + Q+ + L+ + S AE +EEK ++
Sbjct: 1120 PKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELG 1179
Query: 176 VSNAQL---DNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQF 232
S + L E F +V E + Q+A R++ E KN + SIL
Sbjct: 1180 HSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNR 1239
Query: 233 QF----AEVKE------ALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTK 282
Q E KE A ++ + LE+ +L +E A+N + ++ +
Sbjct: 1240 QVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSA--------LR 1291
Query: 283 EELNALKSTGDGTLGRASEVEVKNEIVANVGKREIL 318
EE+ +L+ + R + ++ E+ + + E L
Sbjct: 1292 EEVQSLREEAEKQ--RVASENLRQELTSQAERAEEL 1325
Score = 41.6 bits (96), Expect = 0.003
Identities = 127/692 (18%), Positives = 270/692 (39%), Gaps = 77/692 (11%)
Query: 138 ELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKD 197
+L++L++ + ++ Q E+ + ++E ++A A L T +V+ L+
Sbjct: 386 KLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEA----ATLAANNTQLQARVEMLET 441
Query: 198 MLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNS 257
+ E +L R +EE+ ++ + LQ + + +A ++ E+ + HG L +
Sbjct: 442 ERGQQEAKLLAERGHFEEEKQQLSS---LITDLQSSISNLSQAKEELEQASQAHGARLTA 498
Query: 258 EIATNGETSDTLNNVGYQ------GPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVAN 311
++A+ TLN Q G + KE+ L T + + + E +++
Sbjct: 499 QVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSS 558
Query: 312 VGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQV 371
K++ E + E T +D ++ A E E D A L L E+
Sbjct: 559 SLKQKEQQLKEVAEKQEATRQDHAQ-QLATAAEEREASLRERDAA--LKQLEALEKEKAA 615
Query: 372 QSQILESSSLPENTVQVES-NEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQ 430
+ +IL+ N + + V A ++ + + ++ ++ +A V +
Sbjct: 616 KLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAE 675
Query: 431 VEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETS---TGHSLEKEFTNQEAAEPKEV 487
+E Q + + V + + E Q L+ S T SLE+E + AA+ E
Sbjct: 676 LELQLRSEQQ--KATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEE--KRRAADALE- 730
Query: 488 PAHSTEVGRDHNEEEGEETGL-----RDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQ- 541
E R +E + E L R+ K ++ E G G E Q+ +T+
Sbjct: 731 -----EQQRCISELKAETRSLVEQHKRERKELEEERAGR-KGLEARLQQLGEAHQAETEV 784
Query: 542 -----NEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELT 596
E + + E + +Q + + + +++ ++ +++ + + + E L +K+E
Sbjct: 785 LRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQE-EAQYGAMFQEQLMTLKEECE 843
Query: 597 YQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKL 656
+L E KE + + +E+ +E+ + +Q AE N+ + + +
Sbjct: 844 KARQELQEAKE--------KVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRA 895
Query: 657 DQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPA 716
+ DD+ T E++ A + + V+ +G E E +++ K
Sbjct: 896 QKLADDLSTLQEKMAATSKEVARLETLVRKAG------EQQETASRELVK---------- 939
Query: 717 EPKSEDADRCTLPEHESPSQDISDACEAESTER-CEMSEHPSQTVRKALDSNSLENDDLS 775
EP + E + Q S ++ ER E + + +R AL +
Sbjct: 940 EPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAAL---------ME 990
Query: 776 APGREPGHFNPESREDTRGGNEKGKSKEDCTM 807
+ G++ + RE R E+G+++ D +
Sbjct: 991 SQGQQQEERGQQEREVARLTQERGRAQADLAL 1022
Score = 38.9 bits (89), Expect = 0.019
Identities = 45/233 (19%), Positives = 101/233 (43%), Gaps = 28/233 (12%)
Query: 19 AQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRNTSASDEDERMSVGS 78
AQ+LA A A +R A R+ +K+LE +KE+ ++ + + + D +
Sbjct: 582 AQQLATA--AEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARD-----SA 634
Query: 79 RGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISI-DTEASIREIK 137
+ S+ +R + + SR + L A ++R+ + + + E +R +
Sbjct: 635 QTSVTQAQREKAEL----SRKVEELQACV------ETARQEQHEAQAQVAELELQLRSEQ 684
Query: 138 ELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKD 197
+ K+++ + + + L+ +K+SL V+ L+ EK ++ +
Sbjct: 685 QKATEKERVAQEKDQLQEQLQALKESL----------KVTKGSLEEEKRRAADALEEQQR 734
Query: 198 MLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEK 250
+ EL+ + Q++ + KE E E+ L+ + ++ EA + E+L +
Sbjct: 735 CISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRR 787
Score = 34.7 bits (78), Expect = 0.36
Identities = 50/241 (20%), Positives = 93/241 (38%), Gaps = 48/241 (19%)
Query: 19 AQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR---------SRRNTSASD 69
AQKLA+ + A ++E+ E ++ E E SR R+ +
Sbjct: 895 AQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEE 954
Query: 70 EDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDT 129
+ R ++ +L+ ER E+ + L AA + S G RG +
Sbjct: 955 QQGRQFCSTQAALQAMERE----AEQMGNELERLRAALMESQGQQQEERGQQE------- 1003
Query: 130 EASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFM 189
RE+ L + + G+ L K + AE+E + + A L+ ++ F
Sbjct: 1004 ----REVARLTQER-------GRAQADLALEKAARAELEMRLQNA------LNEQRVEFA 1046
Query: 190 YQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLE 249
L+E LA + + E K++E + + + + E+++ +KQ +E L
Sbjct: 1047 -----------TLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLA 1095
Query: 250 K 250
K
Sbjct: 1096 K 1096
Score = 32.7 bits (73), Expect = 1.4
Identities = 55/268 (20%), Positives = 94/268 (35%), Gaps = 53/268 (19%)
Query: 5 AAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRN 64
AAA+ R + L Q R RA R I ++ QK + ER +++ R
Sbjct: 1375 AAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLR-----QKVAEQERTAQQLRAE 1429
Query: 65 TSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTS 124
++ E M + G L E R G R G
Sbjct: 1430 KASYAEQLSMLKKAHGLLAEENR-------------------------GLGERANLGRQF 1464
Query: 125 ISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNE 184
+ ++ + + RE K + EL D E + + +E + + E+E K + ++ E
Sbjct: 1465 LEVELDQA-RE-KYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEE 1522
Query: 185 KTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSI--------------- 229
+ F + L + +LE E +Q EE +K+ A +
Sbjct: 1523 RQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGES 1582
Query: 230 ------LQFQFAEVKEALKQREEMLEKH 251
LQ Q E++ L Q+E+ E +
Sbjct: 1583 QQEAQRLQAQLNELQAQLSQKEQAAEHY 1610
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.302 0.122 0.325
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,928,402
Number of Sequences: 37866
Number of extensions: 1597013
Number of successful extensions: 14405
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 286
Number of HSP's successfully gapped in prelim test: 1097
Number of HSP's that attempted gapping in prelim test: 8189
Number of HSP's gapped (non-prelim): 5194
length of query: 808
length of database: 18,247,518
effective HSP length: 110
effective length of query: 698
effective length of database: 14,082,258
effective search space: 9829416084
effective search space used: 9829416084
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.