Guide to the Human Genome
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Search of human proteins with 21040257

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21040257 TruB pseudouridine (psi) synthase homolog 1 [Homo
sapiens]
         (349 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21040257 TruB pseudouridine (psi) synthase homolog 1 [Homo sa...   677   0.0  
gi|7661556 TruB pseudouridine (psi) synthase homolog 2 [Homo sap...   112   5e-25
gi|4503337 dyskerin isoform 1 [Homo sapiens]                           67   2e-11
gi|215599015 dyskerin isoform 2 [Homo sapiens]                         67   2e-11
gi|10863903 thyroid hormone receptor interactor 12 [Homo sapiens]      35   0.13 
gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]          33   0.38 
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             33   0.50 
gi|19923559 EMSY protein [Homo sapiens]                                33   0.50 
gi|7661892 REST corepressor 1 [Homo sapiens]                           32   0.65 
gi|223646113 Sp9 transcription factor homolog [Homo sapiens]           32   1.1  
gi|239748752 PREDICTED: hypothetical protein XP_002346787 [Homo ...    32   1.1  
gi|225735627 disco-interacting protein 2A isoform f [Homo sapiens]     32   1.1  
gi|151301228 formin binding protein 3 [Homo sapiens]                   32   1.1  
gi|110349719 titin isoform N2-A [Homo sapiens]                         31   1.4  
gi|110349717 titin isoform novex-2 [Homo sapiens]                      31   1.4  
gi|110349713 titin isoform novex-1 [Homo sapiens]                      31   1.4  
gi|110349715 titin isoform N2-B [Homo sapiens]                         31   1.4  
gi|50428940 mediator complex subunit 25 [Homo sapiens]                 31   1.4  
gi|19111150 angiomotin isoform 2 [Homo sapiens]                        31   1.9  
gi|166064029 angiomotin isoform 1 [Homo sapiens]                       31   1.9  
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             31   1.9  
gi|110347459 MYC-associated zinc finger protein isoform 2 [Homo ...    30   2.5  
gi|110347461 MYC-associated zinc finger protein isoform 1 [Homo ...    30   2.5  
gi|116256464 hypothetical protein LOC343990 [Homo sapiens]             30   2.5  
gi|47419907 T-box 3 protein isoform 2 [Homo sapiens]                   30   3.2  
gi|47419905 T-box 3 protein isoform 1 [Homo sapiens]                   30   3.2  
gi|115511046 zinc finger protein 258 [Homo sapiens]                    30   3.2  
gi|194248057 growth associated protein 43 isoform 1 [Homo sapiens]     30   3.2  
gi|4503911 growth associated protein 43 isoform 2 [Homo sapiens]       30   3.2  
gi|222446620 hypothetical protein LOC342346 [Homo sapiens]             30   4.2  

>gi|21040257 TruB pseudouridine (psi) synthase homolog 1 [Homo
           sapiens]
          Length = 349

 Score =  677 bits (1747), Expect = 0.0
 Identities = 349/349 (100%), Positives = 349/349 (100%)

Query: 1   MAASEAAVVSSPSLKTDTSPVLETAGTVAAMAATPSARAAAAVVAAAARTGSEARVSKAA 60
           MAASEAAVVSSPSLKTDTSPVLETAGTVAAMAATPSARAAAAVVAAAARTGSEARVSKAA
Sbjct: 1   MAASEAAVVSSPSLKTDTSPVLETAGTVAAMAATPSARAAAAVVAAAARTGSEARVSKAA 60

Query: 61  LATKLLSLSGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWTKRKKQTLKIGHGGTL 120
           LATKLLSLSGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWTKRKKQTLKIGHGGTL
Sbjct: 61  LATKLLSLSGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWTKRKKQTLKIGHGGTL 120

Query: 121 DSAARGVLVVGIGSGTKMLTSMLSGSKRYTAIGELGKATDTLDSTGRVTEEKPYDKITQE 180
           DSAARGVLVVGIGSGTKMLTSMLSGSKRYTAIGELGKATDTLDSTGRVTEEKPYDKITQE
Sbjct: 121 DSAARGVLVVGIGSGTKMLTSMLSGSKRYTAIGELGKATDTLDSTGRVTEEKPYDKITQE 180

Query: 181 DIEGILQKFTGNIMQVPPLYSALKKDGQRLSTLMKRGEVVEAKPARPVTVYSISLQKFQP 240
           DIEGILQKFTGNIMQVPPLYSALKKDGQRLSTLMKRGEVVEAKPARPVTVYSISLQKFQP
Sbjct: 181 DIEGILQKFTGNIMQVPPLYSALKKDGQRLSTLMKRGEVVEAKPARPVTVYSISLQKFQP 240

Query: 241 PFFTLDVECGGGFYIRSLVSDIGKELSSCANVLELTRTKQGPFTLEEHALPEDKWTIDDI 300
           PFFTLDVECGGGFYIRSLVSDIGKELSSCANVLELTRTKQGPFTLEEHALPEDKWTIDDI
Sbjct: 241 PFFTLDVECGGGFYIRSLVSDIGKELSSCANVLELTRTKQGPFTLEEHALPEDKWTIDDI 300

Query: 301 AQSLEHCSSLFPAELALKKSKPESNEQVLSCEYITLNEPKREDDVIKTC 349
           AQSLEHCSSLFPAELALKKSKPESNEQVLSCEYITLNEPKREDDVIKTC
Sbjct: 301 AQSLEHCSSLFPAELALKKSKPESNEQVLSCEYITLNEPKREDDVIKTC 349


>gi|7661556 TruB pseudouridine (psi) synthase homolog 2 [Homo
           sapiens]
          Length = 331

 Score =  112 bits (280), Expect = 5e-25
 Identities = 92/306 (30%), Positives = 140/306 (45%), Gaps = 42/306 (13%)

Query: 65  LLSLSGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSP--------------EWTKRKKQ 110
           L  L G+FAV+KP G     L + ++ +LL       P              E ++ K+ 
Sbjct: 6   LSRLHGLFAVYKPPGLKWKHLRDTVELQLLKGLNARKPPAPKQRVRFLLGPMEGSEEKEL 65

Query: 111 TL----------------------KIGHGGTLDSAARGVLVVGIGSGTKMLTSMLSG--S 146
           TL                      K+G G  LD+ A GVLV+G+G G ++LT M +   +
Sbjct: 66  TLTATSVPSFINHPLVCGPAFAHLKVGVGHRLDAQASGVLVLGVGHGCRLLTDMYNAHLT 125

Query: 147 KRYTAIGELGKATDTLDSTGRVTEEKPYDKITQEDIEGILQKFTGNIMQVPPLYSALKKD 206
           K YT  G LGKATD     GR+ E+  YD +T+E ++ IL    G+  +   +YS L   
Sbjct: 126 KDYTVRGLLGKATDDFREDGRLVEKTTYDHVTREKLDRILAVIQGSHQKALVMYSNLDLK 185

Query: 207 GQRLSTLMKRGEVVEAKPARPVTVYSISLQKFQPPFFTLDVECGGGFY--IRSLVSDIGK 264
            Q    +  RG ++      P+ +  I    F PP F L+V+C       +R LV +IG 
Sbjct: 186 TQEAYEMAVRG-LIRPMNKSPMLITGIRCLYFAPPEFLLEVQCMHETQKELRKLVHEIGL 244

Query: 265 ELSSCANVLELTRTKQGPFTLEEHALPEDKWTIDDIAQSLEHCSSLFPAELALKKSKPES 324
           EL + A   ++ RT+ G FTL+  AL   +W + +I  ++   +    AEL    S    
Sbjct: 245 ELKTTAVCTQVRRTRDGFFTLDS-ALLRTQWDLTNIQDAIRAATPQVAAELEKSLSPGLD 303

Query: 325 NEQVLS 330
            +Q+ S
Sbjct: 304 TKQLPS 309


>gi|4503337 dyskerin isoform 1 [Homo sapiens]
          Length = 514

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 62/258 (24%), Positives = 102/258 (39%), Gaps = 54/258 (20%)

Query: 69  SGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWTKRKKQTLKIGHGGTLDSAARGVL 128
           +G   + KP  P+S E++                 W +R  +  K GH GTLD    G L
Sbjct: 89  TGFINLDKPSNPSSHEVV----------------AWIRRILRVEKTGHSGTLDPKVTGCL 132

Query: 129 VVGIGSGTKMLTSMLSGSKRYTAIGELGKATDTLDSTGRVTEEKPYDKITQEDIEGILQK 188
           +V I   T+++ S  S  K Y  I  L  A +      R                  L+ 
Sbjct: 133 IVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRA-----------------LET 175

Query: 189 FTGNIMQVPPLYSALKKDGQRLSTLMKRGEVVEAKPARPVTVYSISLQKFQPPFFTLDVE 248
            TG + Q PPL +A+K+   R+ T+ +  +++E  P R + ++ +S              
Sbjct: 176 LTGALFQRPPLIAAVKRQ-LRVRTIYE-SKMIEYDPERRLGIFWVS-------------- 219

Query: 249 CGGGFYIRSLVSDIGKELSSCANVLELTRTKQGPFTLEEHALP-----EDKWTIDDIAQS 303
           C  G YIR+L   +G  L     + EL R + G  + ++H +      + +W  D+    
Sbjct: 220 CEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDE 279

Query: 304 LEHCSSLFPAELALKKSK 321
                 ++P E  L   K
Sbjct: 280 SYLRRVVYPLEKLLTSHK 297


>gi|215599015 dyskerin isoform 2 [Homo sapiens]
          Length = 509

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 62/258 (24%), Positives = 102/258 (39%), Gaps = 54/258 (20%)

Query: 69  SGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWTKRKKQTLKIGHGGTLDSAARGVL 128
           +G   + KP  P+S E++                 W +R  +  K GH GTLD    G L
Sbjct: 89  TGFINLDKPSNPSSHEVV----------------AWIRRILRVEKTGHSGTLDPKVTGCL 132

Query: 129 VVGIGSGTKMLTSMLSGSKRYTAIGELGKATDTLDSTGRVTEEKPYDKITQEDIEGILQK 188
           +V I   T+++ S  S  K Y  I  L  A +      R                  L+ 
Sbjct: 133 IVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRA-----------------LET 175

Query: 189 FTGNIMQVPPLYSALKKDGQRLSTLMKRGEVVEAKPARPVTVYSISLQKFQPPFFTLDVE 248
            TG + Q PPL +A+K+   R+ T+ +  +++E  P R + ++ +S              
Sbjct: 176 LTGALFQRPPLIAAVKRQ-LRVRTIYE-SKMIEYDPERRLGIFWVS-------------- 219

Query: 249 CGGGFYIRSLVSDIGKELSSCANVLELTRTKQGPFTLEEHALP-----EDKWTIDDIAQS 303
           C  G YIR+L   +G  L     + EL R + G  + ++H +      + +W  D+    
Sbjct: 220 CEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDE 279

Query: 304 LEHCSSLFPAELALKKSK 321
                 ++P E  L   K
Sbjct: 280 SYLRRVVYPLEKLLTSHK 297


>gi|10863903 thyroid hormone receptor interactor 12 [Homo sapiens]
          Length = 1992

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 50/201 (24%), Positives = 79/201 (39%), Gaps = 13/201 (6%)

Query: 15  KTDTSPVLETAGTVAAMAATPSARAA--AAVVAAAARTGSEARVSKAALATKLLSLSGVF 72
           +T++S V   +G+ +  A   SA+    A+  A +A+ G       ++ A+   S S V 
Sbjct: 151 RTESSCVKSGSGSESTGAEERSAKPTKLASKSATSAKAGCSTITDSSSAASTSSSSSAVA 210

Query: 73  AVHK--PKGPTSAELLNRLKEKLLAEAGMPSPEWTKRKKQTLKIGHGGTLDSAARGVLVV 130
           +     P G    +  ++ K +    A  PSP  + R+K+  K G     D AAR    V
Sbjct: 211 SASSTVPPGARVKQGKDQNKARRSRSASSPSPRRSSREKEQSKTGGSSKFDWAARFSPKV 270

Query: 131 GIGSGTKMLTSMLSGSKRYTA----IGELGKATDTLDSTGRVTEEKPYDKITQEDIEGIL 186
            +    K   S+   SK  T+     G   K      ST + +E  P +  +        
Sbjct: 271 SL---PKTKLSLPGSSKSETSKPGPSGLQAKLASLRKSTKKRSESPPAELPSLR--RSTR 325

Query: 187 QKFTGNIMQVPPLYSALKKDG 207
           QK TG+        S L K G
Sbjct: 326 QKTTGSCASTSRRGSGLGKRG 346


>gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
          Length = 887

 Score = 33.1 bits (74), Expect = 0.38
 Identities = 22/56 (39%), Positives = 27/56 (48%), Gaps = 3/56 (5%)

Query: 2   AASEAAVVSSPSLKTDTSPVLETAGT---VAAMAATPSARAAAAVVAAAARTGSEA 54
           AA+ AA   +P+L    +P L  A      AA A  P+  AA AV AA A   S A
Sbjct: 510 AAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAA 565



 Score = 30.0 bits (66), Expect = 3.2
 Identities = 55/243 (22%), Positives = 88/243 (36%), Gaps = 38/243 (15%)

Query: 2   AASEAAVVSSPSLKTDTSPVLETAGTVAAMAATPSARAAAAVVAAAARTGSEARVSKAAL 61
           AA+ AA  ++ +     +P L  A   A  AA   A AAAA  A A         + AA 
Sbjct: 502 AAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAA 561

Query: 62  ATKLLSLSGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWTKRKKQTLKIGHGGTLD 121
           A+   S S      KP  P             L +A  P P   +   + +KI     L 
Sbjct: 562 ASAAPSHS-----QKPSVP-------------LIQASRPCPA-AQPPTKFIKIAPAIQLR 602

Query: 122 SAARGVLVVGIGSGTKMLTSMLSGSKRYTAIGELGKA------TDTLDSTGRVTEEKPYD 175
           + + G+  + +    +   ++ S  K   A G    A      +D   S G + + +P  
Sbjct: 603 TGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARP-- 660

Query: 176 KITQEDIEGILQKFTG--------NIMQVPPLYSAL---KKDGQRLSTLMKRGEVVEAKP 224
              Q      LQ F           ++QVP   + L   ++   +L +L +  +   A P
Sbjct: 661 GAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHP 720

Query: 225 ARP 227
            +P
Sbjct: 721 PQP 723


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 32.7 bits (73), Expect = 0.50
 Identities = 35/108 (32%), Positives = 50/108 (46%), Gaps = 8/108 (7%)

Query: 4    SEAAVVSSPS-----LKTDTSPV--LETAGTVAAMAATPSARAAAAVVAAAARTGSEARV 56
            S AA V +P+     L+  TSP   + T+   A++AA  S        AAA  T  E   
Sbjct: 1197 SPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTS 1256

Query: 57   SKAALATKLLSLSGVFAVHKPKGPTS-AELLNRLKEKLLAEAGMPSPE 103
            S AA+ T     S   +V  P+ P S A  ++ L+E     A +P+PE
Sbjct: 1257 SAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPE 1304



 Score = 32.3 bits (72), Expect = 0.65
 Identities = 31/102 (30%), Positives = 41/102 (40%), Gaps = 1/102 (0%)

Query: 3    ASEAAVVSSPSLKTDTSPVLETAGTVAAMAATPSARAAAAVVAAAARTGSEARVSKAALA 62
            AS AA V +P   T  +  + T     + AA           AAA  T  E     AA+ 
Sbjct: 1001 ASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVP 1060

Query: 63   TKLLSLSGVFAVHKPKGPTS-AELLNRLKEKLLAEAGMPSPE 103
            T     S   AV  P+ PTS A  +   +E     A +P+PE
Sbjct: 1061 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1102



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 30/101 (29%), Positives = 39/101 (38%), Gaps = 1/101 (0%)

Query: 4    SEAAVVSSPSLKTDTSPVLETAGTVAAMAATPSARAAAAVVAAAARTGSEARVSKAALAT 63
            S AA V  P   T  +  + T     + AA           AAA  T  E     AA+ T
Sbjct: 1028 SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1087

Query: 64   KLLSLSGVFAVHKPKGPTS-AELLNRLKEKLLAEAGMPSPE 103
                 S   AV  P+ PTS A  +   +E     A +P+PE
Sbjct: 1088 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPE 1128



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 31/114 (27%), Positives = 45/114 (39%), Gaps = 16/114 (14%)

Query: 6    AAVVSSPSLKTDTSPVLETAGTVAAMAATPSARAAAAVVAAA-------ARTGSEARVSK 58
            AA VS+P   T  +  +      AA+AA  S    A  VAAA       A  G     + 
Sbjct: 898  AAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAA 957

Query: 59   AALATKLLSLSG--------VFAVHKPKGP-TSAELLNRLKEKLLAEAGMPSPE 103
             A+   +    G           VH P+ P T+A  ++  +E     A +P+PE
Sbjct: 958  LAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPE 1011


>gi|19923559 EMSY protein [Homo sapiens]
          Length = 1322

 Score = 32.7 bits (73), Expect = 0.50
 Identities = 33/153 (21%), Positives = 66/153 (43%), Gaps = 14/153 (9%)

Query: 1   MAASEAAVVS---SPSLKTDTSPVLETAGTVAAMAATPS---ARAAAAVVAAAARTGSEA 54
           + AS++++VS   S S  +  SP+  T    A +++TPS   +  A  V  +A +  S  
Sbjct: 323 ITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTR 382

Query: 55  RVSKAALATKLLSLSGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWTKRKKQTLKI 114
             S  +L +    +   F     + P   + L +++++   +   PSP   +++ Q    
Sbjct: 383 LPSPKSLVSAPTQILAQFPKQHQQSP--KQQLYQVQQQTQQQVAQPSPVSHQQQPQQ--- 437

Query: 115 GHGGTLDSAARGVLVVGIGSGTKMLTSMLSGSK 147
                L    +  + +   SG K++T  +  SK
Sbjct: 438 ---SPLPPGIKPTIQIKQESGVKIITQQVQPSK 467


>gi|7661892 REST corepressor 1 [Homo sapiens]
          Length = 482

 Score = 32.3 bits (72), Expect = 0.65
 Identities = 23/59 (38%), Positives = 30/59 (50%), Gaps = 4/59 (6%)

Query: 2  AASEAAVVSSPSLKTDTSPVLETAGTVAAMAATPSARAAAAVVAAAARTGSEARVSKAA 60
          A++ AA  S+ +     SP    A T A+ AA  SA AAAA  AAA   G    ++ AA
Sbjct: 20 ASASAAAASAAASAACASP----AATAASGAAASSASAAAASAAAAPNNGQNKSLAAAA 74


>gi|223646113 Sp9 transcription factor homolog [Homo sapiens]
          Length = 484

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 17/34 (50%), Positives = 21/34 (61%)

Query: 21  VLETAGTVAAMAATPSARAAAAVVAAAARTGSEA 54
           +L  +G  AA AA  +A AAAA  AAA+  G EA
Sbjct: 444 ILHDSGVSAARAAAAAAAAAAAAAAAASAGGKEA 477


>gi|239748752 PREDICTED: hypothetical protein XP_002346787 [Homo
           sapiens]
          Length = 278

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 32/113 (28%), Positives = 43/113 (38%), Gaps = 10/113 (8%)

Query: 31  MAATPSARAAAAVVAAAARTGSEARVSKAALATKLLSLSGVFAVHKPKGPTSAELLNRLK 90
           MA T    A   V    AR GS    ++A  +           +  P  P S+       
Sbjct: 159 MATTRGPEAGLRVSGRGARAGSSTAPTRAQASPARPGFPP--CLRSPPCPASSRAFRSCL 216

Query: 91  EKLLA------EAGMPSPEWTKRKKQTLKIGHGG--TLDSAARGVLVVGIGSG 135
            +  A       AG PS +W + +KQ  K G  G   L S  R VL+ G+ SG
Sbjct: 217 SRAKAWDTAGQTAGQPSEKWEEGRKQWRKEGLLGRSALGSWTRWVLLRGLRSG 269


>gi|225735627 disco-interacting protein 2A isoform f [Homo sapiens]
          Length = 798

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 46/197 (23%), Positives = 76/197 (38%), Gaps = 26/197 (13%)

Query: 27  TVAAMAATPSARAAAAVVAAAARTGSEARVSKAALATKLLSLSGVFAVHKPKGPTSAELL 86
           T  + AATP A A  A+    A T     V+ + +++K+  L  +  + +PK P   E  
Sbjct: 193 TAPSAAATPGAAATTALAGLEAHTHIGVPVN-SRVSSKIQQL--LNTLKRPKRPPLKEFF 249

Query: 87  NRLKEKLLAEAGMPSPEWTKRKKQTLKIGHGGTLDSAARGVLVVGIGSGTKMLTSMLSGS 146
               E+LL E   P P   K +         G+  S  RG     + +G     S+L+  
Sbjct: 250 VDDFEELL-EVQQPDPNQPKPE---------GSETSVLRG---EPLTAGVPRPPSLLATL 296

Query: 147 KRYTAIGELGKATDTLDSTGRVTEEKPYDKITQEDIE---GILQKFTGNIMQVPPLYSAL 203
           +R+            LD+TG+      Y K+    ++    +L K T            L
Sbjct: 297 QRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSK-------NEPL 349

Query: 204 KKDGQRLSTLMKRGEVV 220
            K G R++ +    + V
Sbjct: 350 LKPGDRVALVFPNSDPV 366


>gi|151301228 formin binding protein 3 [Homo sapiens]
          Length = 930

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 5/65 (7%)

Query: 1   MAASEAAVVSSPSLKTDTSPV--LETAGTVAAMAATPSARAAAAVVAAAARTGSEARVSK 58
           M  +E +        T T+PV   E   T++ MAA   A AAAAVVAAAA   + A  + 
Sbjct: 212 MIKAEESSKQEECTTTSTAPVPTTEIPTTMSTMAA---AEAAAAVVAAAAAAAAAAAAAN 268

Query: 59  AALAT 63
           A  +T
Sbjct: 269 ANAST 273



 Score = 29.3 bits (64), Expect = 5.5
 Identities = 17/54 (31%), Positives = 23/54 (42%)

Query: 10  SSPSLKTDTSPVLETAGTVAAMAATPSARAAAAVVAAAARTGSEARVSKAALAT 63
           ++P   T+    + T     A AA  +A AAAA  AAAA   +    S     T
Sbjct: 229 TAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNTVSGT 282


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 39/153 (25%), Positives = 66/153 (43%), Gaps = 17/153 (11%)

Query: 143   LSGSKRYTAIGELGKATDTLDSTGR-VTEEKP--YDKITQEDIEGILQKFTGNIMQVPPL 199
             LS +  YT +  LG    T  ST + V EE P  + K  +E++          +++  PL
Sbjct: 11182 LSDAGEYTCVLRLGNKEKT--STAKLVVEELPVRFVKTLEEEV---------TVVKGQPL 11230

Query: 200   YSALKKDGQRLSTLMKRGEVVEAKPARPVTVYSISLQKFQPPFFTLDVECGGGFYIRSLV 259
             Y + + + +R     K G++V  KP R +    I L +        D +   G Y  ++ 
Sbjct: 11231 YLSCELNKERDVVWRKDGKIVVEKPGR-IVPGVIGLMRALTINDADDTD--AGTYTVTVE 11287

Query: 260   SDIGKELSSCANVLELTRTKQGPFTLEEHALPE 292
             +    E SSC  V+E+ R        ++H  P+
Sbjct: 11288 NANNLECSSCVKVVEVIRDWLVKPIRDQHVKPK 11320


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 39/153 (25%), Positives = 66/153 (43%), Gaps = 17/153 (11%)

Query: 143  LSGSKRYTAIGELGKATDTLDSTGR-VTEEKP--YDKITQEDIEGILQKFTGNIMQVPPL 199
            LS +  YT +  LG    T  ST + V EE P  + K  +E++          +++  PL
Sbjct: 4877 LSDAGEYTCVLRLGNKEKT--STAKLVVEELPVRFVKTLEEEV---------TVVKGQPL 4925

Query: 200  YSALKKDGQRLSTLMKRGEVVEAKPARPVTVYSISLQKFQPPFFTLDVECGGGFYIRSLV 259
            Y + + + +R     K G++V  KP R +    I L +        D +   G Y  ++ 
Sbjct: 4926 YLSCELNKERDVVWRKDGKIVVEKPGR-IVPGVIGLMRALTINDADDTD--AGTYTVTVE 4982

Query: 260  SDIGKELSSCANVLELTRTKQGPFTLEEHALPE 292
            +    E SSC  V+E+ R        ++H  P+
Sbjct: 4983 NANNLECSSCVKVVEVIRDWLVKPIRDQHVKPK 5015


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 39/153 (25%), Positives = 66/153 (43%), Gaps = 17/153 (11%)

Query: 143  LSGSKRYTAIGELGKATDTLDSTGR-VTEEKP--YDKITQEDIEGILQKFTGNIMQVPPL 199
            LS +  YT +  LG    T  ST + V EE P  + K  +E++          +++  PL
Sbjct: 4810 LSDAGEYTCVLRLGNKEKT--STAKLVVEELPVRFVKTLEEEV---------TVVKGQPL 4858

Query: 200  YSALKKDGQRLSTLMKRGEVVEAKPARPVTVYSISLQKFQPPFFTLDVECGGGFYIRSLV 259
            Y + + + +R     K G++V  KP R +    I L +        D +   G Y  ++ 
Sbjct: 4859 YLSCELNKERDVVWRKDGKIVVEKPGR-IVPGVIGLMRALTINDADDTD--AGTYTVTVE 4915

Query: 260  SDIGKELSSCANVLELTRTKQGPFTLEEHALPE 292
            +    E SSC  V+E+ R        ++H  P+
Sbjct: 4916 NANNLECSSCVKVVEVIRDWLVKPIRDQHVKPK 4948


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 39/153 (25%), Positives = 66/153 (43%), Gaps = 17/153 (11%)

Query: 143  LSGSKRYTAIGELGKATDTLDSTGR-VTEEKP--YDKITQEDIEGILQKFTGNIMQVPPL 199
            LS +  YT +  LG    T  ST + V EE P  + K  +E++          +++  PL
Sbjct: 4685 LSDAGEYTCVLRLGNKEKT--STAKLVVEELPVRFVKTLEEEV---------TVVKGQPL 4733

Query: 200  YSALKKDGQRLSTLMKRGEVVEAKPARPVTVYSISLQKFQPPFFTLDVECGGGFYIRSLV 259
            Y + + + +R     K G++V  KP R +    I L +        D +   G Y  ++ 
Sbjct: 4734 YLSCELNKERDVVWRKDGKIVVEKPGR-IVPGVIGLMRALTINDADDTD--AGTYTVTVE 4790

Query: 260  SDIGKELSSCANVLELTRTKQGPFTLEEHALPE 292
            +    E SSC  V+E+ R        ++H  P+
Sbjct: 4791 NANNLECSSCVKVVEVIRDWLVKPIRDQHVKPK 4823


>gi|50428940 mediator complex subunit 25 [Homo sapiens]
          Length = 747

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 12/91 (13%)

Query: 10  SSPSLKTDTSPVLETAGTVAAMAATPSARAAAAVVA-------AAARTGSEARVSKAALA 62
           S PSL +  +P     G+  A  A P A + A  VA       + A+ G+ A   + +++
Sbjct: 342 SQPSLVSTVAP-----GSGLAPTAQPGAPSMAGTVAPGGVSGPSPAQLGAPALGGQQSVS 396

Query: 63  TKLLSLSGVFAVHKPKGPTSAELLNRLKEKL 93
            KLL+ SGV    +   P S +   +L   L
Sbjct: 397 NKLLAWSGVLEWQEKPKPASVDANTKLTRSL 427


>gi|19111150 angiomotin isoform 2 [Homo sapiens]
          Length = 675

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 29/113 (25%), Positives = 46/113 (40%), Gaps = 12/113 (10%)

Query: 1   MAASEAAVVSSPSLKTDTSPVLETAGTVAAMAATPSARAA-----AAVVAAAARTGSEAR 55
           +AA+  A   + +  T T+ ++  A    A AA P+A AA     AA  AAA    +  +
Sbjct: 478 VAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQ 537

Query: 56  V-------SKAALATKLLSLSGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPS 101
           +       S AA+A    + + V        P  A  L  +     A+A  P+
Sbjct: 538 IPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPA 590


>gi|166064029 angiomotin isoform 1 [Homo sapiens]
          Length = 1084

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 29/113 (25%), Positives = 46/113 (40%), Gaps = 12/113 (10%)

Query: 1   MAASEAAVVSSPSLKTDTSPVLETAGTVAAMAATPSARAA-----AAVVAAAARTGSEAR 55
           +AA+  A   + +  T T+ ++  A    A AA P+A AA     AA  AAA    +  +
Sbjct: 887 VAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQ 946

Query: 56  V-------SKAALATKLLSLSGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPS 101
           +       S AA+A    + + V        P  A  L  +     A+A  P+
Sbjct: 947 IPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPA 999


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 6/74 (8%)

Query: 2    AASEAAVVSSPSLKTDTSPVLETAGTVAAMAATPSARAAAAVVAAAARTGSE------AR 55
            A++ A V++S S     SP+   + + +  A+ P++ +AAA+ +++A   +       A 
Sbjct: 1787 ASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILAS 1846

Query: 56   VSKAALATKLLSLS 69
            VS  A  T L S S
Sbjct: 1847 VSTPASVTILASAS 1860


>gi|110347459 MYC-associated zinc finger protein isoform 2 [Homo
           sapiens]
          Length = 493

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 22/48 (45%), Positives = 26/48 (54%), Gaps = 1/48 (2%)

Query: 14  LKTDTSPVLETAGTVAAMAATPSARAAAAVVAAAARTGSEARVSKAAL 61
           L+ D  PVL  A   AA AA  +A AAAAV AA     + + V  AAL
Sbjct: 81  LQVDLLPVLAAAQESAAAAAAAAA-AAAAVAAAPPAPAAASTVDTAAL 127


>gi|110347461 MYC-associated zinc finger protein isoform 1 [Homo
           sapiens]
          Length = 477

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 22/48 (45%), Positives = 26/48 (54%), Gaps = 1/48 (2%)

Query: 14  LKTDTSPVLETAGTVAAMAATPSARAAAAVVAAAARTGSEARVSKAAL 61
           L+ D  PVL  A   AA AA  +A AAAAV AA     + + V  AAL
Sbjct: 81  LQVDLLPVLAAAQESAAAAAAAAA-AAAAVAAAPPAPAAASTVDTAAL 127


>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
          Length = 962

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 42/148 (28%), Positives = 55/148 (37%), Gaps = 20/148 (13%)

Query: 2   AASEAAVVSSPSLKTDTSPVLETAGTVAAMAAT---PSARAAAAVVAAAARTGSEARVSK 58
           AASE    S P    ++ PV    G++ A AA    P A  A A  A A R   E +  +
Sbjct: 504 AASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAER 563

Query: 59  AAL---ATKLLSLSGVFA-----VHKPKGPTSAEL-LNRLKEKLLAEA------GMPSPE 103
                   K  S+S   A     V +P    S  L L R      +EA      G+P P+
Sbjct: 564 GGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQ 623

Query: 104 WTKRKKQTLKIGHGGTLDSAARGVLVVG 131
             K   +  K+   G  DS  R     G
Sbjct: 624 HAKPGPR--KLAERGPQDSGDRAASPAG 649


>gi|47419907 T-box 3 protein isoform 2 [Homo sapiens]
          Length = 743

 Score = 30.0 bits (66), Expect = 3.2
 Identities = 27/91 (29%), Positives = 39/91 (42%), Gaps = 4/91 (4%)

Query: 10  SSPSLKTDTSPVLETAGTVAAMAATPS----ARAAAAVVAAAARTGSEARVSKAALATKL 65
           S P    D S +L TA    A AA P     A  AA+  + A  +GSE     + L++  
Sbjct: 644 SIPVPVPDGSSLLTTALPSMAAAAGPLDGKVAALAASPASVAVDSGSELNSRSSTLSSSS 703

Query: 66  LSLSGVFAVHKPKGPTSAELLNRLKEKLLAE 96
           +SLS      K    +  + + RL   L A+
Sbjct: 704 MSLSPKLCAEKEAATSELQSIQRLVSGLEAK 734


>gi|47419905 T-box 3 protein isoform 1 [Homo sapiens]
          Length = 723

 Score = 30.0 bits (66), Expect = 3.2
 Identities = 27/91 (29%), Positives = 39/91 (42%), Gaps = 4/91 (4%)

Query: 10  SSPSLKTDTSPVLETAGTVAAMAATPS----ARAAAAVVAAAARTGSEARVSKAALATKL 65
           S P    D S +L TA    A AA P     A  AA+  + A  +GSE     + L++  
Sbjct: 624 SIPVPVPDGSSLLTTALPSMAAAAGPLDGKVAALAASPASVAVDSGSELNSRSSTLSSSS 683

Query: 66  LSLSGVFAVHKPKGPTSAELLNRLKEKLLAE 96
           +SLS      K    +  + + RL   L A+
Sbjct: 684 MSLSPKLCAEKEAATSELQSIQRLVSGLEAK 714


>gi|115511046 zinc finger protein 258 [Homo sapiens]
          Length = 1325

 Score = 30.0 bits (66), Expect = 3.2
 Identities = 15/47 (31%), Positives = 28/47 (59%)

Query: 1   MAASEAAVVSSPSLKTDTSPVLETAGTVAAMAATPSARAAAAVVAAA 47
           ++ ++ AV   PS +TDT+PV+ +  ++A + AT S     +V+  A
Sbjct: 607 ISKAKTAVTELPSARTDTTPVITSVMSLAKIPATLSTGNTNSVLKGA 653


>gi|194248057 growth associated protein 43 isoform 1 [Homo sapiens]
          Length = 274

 Score = 30.0 bits (66), Expect = 3.2
 Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 7/56 (12%)

Query: 2   AASEAAVVSSPSLKTDTSPVLET-------AGTVAAMAATPSARAAAAVVAAAART 50
           +A++A+  +SPS K + +P  E        A   AA A TP+A  AAA   A   T
Sbjct: 178 SATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAATTPAAEDAAAKATAQPPT 233


>gi|4503911 growth associated protein 43 isoform 2 [Homo sapiens]
          Length = 238

 Score = 30.0 bits (66), Expect = 3.2
 Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 7/56 (12%)

Query: 2   AASEAAVVSSPSLKTDTSPVLET-------AGTVAAMAATPSARAAAAVVAAAART 50
           +A++A+  +SPS K + +P  E        A   AA A TP+A  AAA   A   T
Sbjct: 142 SATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAATTPAAEDAAAKATAQPPT 197


>gi|222446620 hypothetical protein LOC342346 [Homo sapiens]
          Length = 1141

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 20/53 (37%), Positives = 28/53 (52%)

Query: 27  TVAAMAATPSARAAAAVVAAAARTGSEARVSKAALATKLLSLSGVFAVHKPKG 79
           T AA+AA  +A  AAA  +AA      A+  K A ATK+ +++   A   P G
Sbjct: 566 TTAAIAAAAAAAYAAATSSAAQAAKVAAKFVKDAPATKMAAIATDTAAAGPLG 618



 Score = 28.9 bits (63), Expect = 7.2
 Identities = 20/64 (31%), Positives = 27/64 (42%)

Query: 18  TSPVLETAGTVAAMAATPSARAAAAVVAAAARTGSEARVSKAALATKLLSLSGVFAVHKP 77
           T+  +  A   A  AAT SA  AA V A   +     +++  A  T      GVFA    
Sbjct: 566 TTAAIAAAAAAAYAAATSSAAQAAKVAAKFVKDAPATKMAAIATDTAAAGPLGVFADVLG 625

Query: 78  KGPT 81
            GP+
Sbjct: 626 AGPS 629


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.128    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,683,719
Number of Sequences: 37866
Number of extensions: 540886
Number of successful extensions: 1910
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 41
Number of HSP's that attempted gapping in prelim test: 1737
Number of HSP's gapped (non-prelim): 154
length of query: 349
length of database: 18,247,518
effective HSP length: 103
effective length of query: 246
effective length of database: 14,347,320
effective search space: 3529440720
effective search space used: 3529440720
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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