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Search of human proteins with 210147470
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|210147470 NK2 transcription factor related, locus 6 [Homo
sapiens]
(219 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|210147470 NK2 transcription factor related, locus 6 [Homo sap... 456 e-129
gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens] 202 2e-52
gi|148746211 NK2 transcription factor related, locus 3 [Homo sap... 197 4e-51
gi|4505401 NK2 transcription factor related, locus 2 [Homo sapiens] 139 1e-33
gi|157426823 NK2 homeobox 4 [Homo sapiens] 137 9e-33
gi|118766339 thyroid transcription factor 1 isoform 1 [Homo sapi... 134 6e-32
gi|4507715 thyroid transcription factor 1 isoform 2 [Homo sapiens] 134 6e-32
gi|31377777 NK2 homeobox 8 [Homo sapiens] 122 2e-28
gi|4502365 NK3 homeobox 2 [Homo sapiens] 107 6e-24
gi|157743259 H6 family homeobox 3 [Homo sapiens] 91 6e-19
gi|116805350 homeo box (H6 family) 1 [Homo sapiens] 90 2e-18
gi|70608170 H6 family homeobox 2 [Homo sapiens] 89 3e-18
gi|19923352 NK3 homeobox 1 [Homo sapiens] 88 6e-18
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens] 87 1e-17
gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens] 87 1e-17
gi|118582284 msh homeobox 1 [Homo sapiens] 86 2e-17
gi|27886557 msh homeobox 2 [Homo sapiens] 86 2e-17
gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens] 85 4e-17
gi|4758168 distal-less homeobox 2 [Homo sapiens] 84 7e-17
gi|24497515 homeobox A3 isoform b [Homo sapiens] 82 4e-16
gi|24497513 homeobox A3 isoform a [Homo sapiens] 82 4e-16
gi|13562112 homeobox A3 isoform a [Homo sapiens] 82 4e-16
gi|226437602 NK1 homeobox 2 [Homo sapiens] 79 3e-15
gi|4885185 distal-less homeobox 3 [Homo sapiens] 79 3e-15
gi|64225290 distal-less homeobox 1 isoform 1 [Homo sapiens] 79 3e-15
gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens] 79 3e-15
gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens] 79 3e-15
gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens] 79 3e-15
gi|147901462 brain specific homeobox [Homo sapiens] 77 1e-14
gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens] 76 2e-14
>gi|210147470 NK2 transcription factor related, locus 6 [Homo
sapiens]
Length = 219
Score = 456 bits (1172), Expect = e-129
Identities = 219/219 (100%), Positives = 219/219 (100%)
Query: 1 MDAERMGEPQPGLNAASPLGGGTRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQA 60
MDAERMGEPQPGLNAASPLGGGTRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQA
Sbjct: 1 MDAERMGEPQPGLNAASPLGGGTRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQA 60
Query: 61 QVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKSLELAGHP 120
QVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKSLELAGHP
Sbjct: 61 QVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKSLELAGHP 120
Query: 121 LTPRRVAVPVLVRDGKPCLGPGPGAPAFPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAG 180
LTPRRVAVPVLVRDGKPCLGPGPGAPAFPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAG
Sbjct: 121 LTPRRVAVPVLVRDGKPCLGPGPGAPAFPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAG 180
Query: 181 APSGPAPHTPLASAGFGHGGQNATPQGHLAATLQGVRAW 219
APSGPAPHTPLASAGFGHGGQNATPQGHLAATLQGVRAW
Sbjct: 181 APSGPAPHTPLASAGFGHGGQNATPQGHLAATLQGVRAW 219
>gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]
Length = 324
Score = 202 bits (514), Expect = 2e-52
Identities = 117/205 (57%), Positives = 137/205 (66%), Gaps = 23/205 (11%)
Query: 35 DSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQV 94
+ +E+P+AR+RRKPRVLFSQAQV LERRFKQQRYLSAPER+ LAS L+LTSTQV
Sbjct: 123 EKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQV 182
Query: 95 KIWFQNRRYKCKRQRQDKSLELAGHPLTP----RRVAVPVLVRDGKPCLG-PGPGAPAFP 149
KIWFQNRRYKCKRQRQD++LEL G P P RR+AVPVLVRDGKPCLG P APA+
Sbjct: 183 KIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLVRDGKPCLGDSAPYAPAYG 242
Query: 150 ---SPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASA------GFGHGG 200
+PY + Y Y GY GA GY +C A P+GP+P P +A FG G
Sbjct: 243 VGLNPY--GYNAYPAYPGYGGAACSPGY-SCTAAYPAGPSPAQPATAAANNNFVNFGVGD 299
Query: 201 QNAT-----PQGHL-AATLQGVRAW 219
NA PQ + +TL G+RAW
Sbjct: 300 LNAVQSPGIPQSNSGVSTLHGIRAW 324
>gi|148746211 NK2 transcription factor related, locus 3 [Homo
sapiens]
Length = 364
Score = 197 bits (502), Expect = 4e-51
Identities = 124/243 (51%), Positives = 139/243 (57%), Gaps = 53/243 (21%)
Query: 27 ERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASA 86
++ + +GD SE+PK R RRKPRVLFSQAQV LERRFKQQRYLSAPEREHLAS+
Sbjct: 125 KKSLETAGDCKAAEESERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASS 184
Query: 87 LQLTSTQVKIWFQNRRYKCKRQRQDKSLELAGH--PLTPRRVAVPVLVRDGKPCLGPGPG 144
L+LTSTQVKIWFQNRRYKCKRQRQDKSLEL H P PRRVAVPVLVRDGKPC+ P
Sbjct: 185 LKLTSTQVKIWFQNRRYKCKRQRQDKSLELGAHAPPPPPRRVAVPVLVRDGKPCV--TPS 242
Query: 145 APAFPSPYSAAVSPYS-----CYG--------------GYSGAPYGAGYGTCYAGAPSGP 185
A A+ +PYS S YS YG + A Y + YG Y G
Sbjct: 243 AQAYGAPYSVGASAYSYNSFPAYGYGNSAAAAAAAAAAAAAAAAYSSSYGCAYPAGGGGG 302
Query: 186 APHTPLAS---------------------AGFGHGGQNATP--QGHLA------ATLQGV 216
T A+ GFG GG +A P QG A TLQG+
Sbjct: 303 GGGTSAATTAMQPACSAAGGGPFVNVSNLGGFGSGG-SAQPLHQGTAAGAACAQGTLQGI 361
Query: 217 RAW 219
RAW
Sbjct: 362 RAW 364
>gi|4505401 NK2 transcription factor related, locus 2 [Homo sapiens]
Length = 273
Score = 139 bits (351), Expect = 1e-33
Identities = 88/181 (48%), Positives = 105/181 (58%), Gaps = 8/181 (4%)
Query: 16 ASPLGGGTRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYL 75
A P ++ PE S D+ + A ++RK RVLFS+AQ LERRF+QQRYL
Sbjct: 94 APPQDSSSKSPEPSADESPDNDKETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYL 153
Query: 76 SAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKSLELAGHPLTPRRVAVPVLVRDG 135
SAPEREHLAS ++LT TQVKIWFQN RYK KR R +K +E+ P +PRRVAVPVLVRDG
Sbjct: 154 SAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKGMEVTPLP-SPRRVAVPVLVRDG 212
Query: 136 KPCLGPGPGAPAFPSPYSAAVSPYSCYGGYS--GAPYGAGYGTCYAGAPSGPAPHTPLAS 193
KPC A + A P+S Y S Y A Y + A P P H PL
Sbjct: 213 KPC--HALKAQDLAAATFQAGIPFSAYSAQSLQHMQYNAQYSS--ASTPQYPTAH-PLVQ 267
Query: 194 A 194
A
Sbjct: 268 A 268
>gi|157426823 NK2 homeobox 4 [Homo sapiens]
Length = 354
Score = 137 bits (344), Expect = 9e-33
Identities = 87/171 (50%), Positives = 103/171 (60%), Gaps = 28/171 (16%)
Query: 9 PQPGLNAASPLGGGTRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERR 68
P G+N A +G T G+ ++ S+ + A RRK RVLFSQAQV LERR
Sbjct: 154 PSAGVNVAG-MGSLT-----GIADAAKSLGPLHAAAAAAAPRRKRRVLFSQAQVYELERR 207
Query: 69 FKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKS---LELAG------- 118
FKQQ+YLSAPEREHLAS + LT TQVKIWFQN RYK KRQ +DK+ L+ G
Sbjct: 208 FKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGGLGPPPP 267
Query: 119 HPLTPRRVAVPVLVRDGKPC-----------LGPGPGAPAFPSPYSAAVSP 158
P +PRRVAVPVLV+DGKPC GP P AP P+P +SP
Sbjct: 268 PPPSPRRVAVPVLVKDGKPCQNGASTPTPGQAGPQPPAPT-PAPELEELSP 317
>gi|118766339 thyroid transcription factor 1 isoform 1 [Homo
sapiens]
Length = 401
Score = 134 bits (337), Expect = 6e-32
Identities = 101/236 (42%), Positives = 115/236 (48%), Gaps = 40/236 (16%)
Query: 9 PQPGLNAAS----PLGGGTRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLA 64
P P A S P G G+G+ GD V + P A RRK RVLFSQAQV
Sbjct: 148 PDPRFPAISRFMGPASGMNMSGMGGLGSLGD-VSKNMAPLPSA-PRRKRRVLFSQAQVYE 205
Query: 65 LERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKSLEL-------- 116
LERRFKQQ+YLSAPEREHLAS + LT TQVKIWFQN RYK KRQ +DK+ +
Sbjct: 206 LERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQQLQQDSGG 265
Query: 117 ------AGHP-------LTPRRVAVPVLVRDGKPCL--GPGPGAPAFPSPYSAAVSPYSC 161
G P +PRRVAVPVLV+DGKPC P PGA + +
Sbjct: 266 GGGGGGTGCPQQQQAQQQSPRRVAVPVLVKDGKPCQAGAPAPGAASLQGHAQQQAQHQAQ 325
Query: 162 YGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGGQNATPQGHLA--ATLQG 215
+ A G G GA G P G GQ+ H A A LQG
Sbjct: 326 AAQAAAAAISVGSGGAGLGAHPGHQP---------GSAGQSPDLAHHAASPAALQG 372
>gi|4507715 thyroid transcription factor 1 isoform 2 [Homo sapiens]
Length = 371
Score = 134 bits (337), Expect = 6e-32
Identities = 101/236 (42%), Positives = 115/236 (48%), Gaps = 40/236 (16%)
Query: 9 PQPGLNAAS----PLGGGTRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLA 64
P P A S P G G+G+ GD V + P A RRK RVLFSQAQV
Sbjct: 118 PDPRFPAISRFMGPASGMNMSGMGGLGSLGD-VSKNMAPLPSA-PRRKRRVLFSQAQVYE 175
Query: 65 LERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKSLEL-------- 116
LERRFKQQ+YLSAPEREHLAS + LT TQVKIWFQN RYK KRQ +DK+ +
Sbjct: 176 LERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQQLQQDSGG 235
Query: 117 ------AGHP-------LTPRRVAVPVLVRDGKPCL--GPGPGAPAFPSPYSAAVSPYSC 161
G P +PRRVAVPVLV+DGKPC P PGA + +
Sbjct: 236 GGGGGGTGCPQQQQAQQQSPRRVAVPVLVKDGKPCQAGAPAPGAASLQGHAQQQAQHQAQ 295
Query: 162 YGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGGQNATPQGHLA--ATLQG 215
+ A G G GA G P G GQ+ H A A LQG
Sbjct: 296 AAQAAAAAISVGSGGAGLGAHPGHQP---------GSAGQSPDLAHHAASPAALQG 342
>gi|31377777 NK2 homeobox 8 [Homo sapiens]
Length = 239
Score = 122 bits (306), Expect = 2e-28
Identities = 76/141 (53%), Positives = 82/141 (58%), Gaps = 24/141 (17%)
Query: 47 ARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCK 106
A +R+K RVLFS+AQ L LERRF+QQRYLSAPERE LAS L+LT TQVKIWFQN RYK K
Sbjct: 81 AEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLK 140
Query: 107 RQRQD---------KSLELAGHPLTPRRVAVPVLVRDGKPCLGPG--------------- 142
R R S EL P RRV VPVLVRDG+PC G G
Sbjct: 141 RARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGGGGEVGTAAAQEKCGA 200
Query: 143 PGAPAFPSPYSAAVSPYSCYG 163
P A A P P A P S G
Sbjct: 201 PPAAACPLPGYPAFGPGSALG 221
>gi|4502365 NK3 homeobox 2 [Homo sapiens]
Length = 333
Score = 107 bits (268), Expect = 6e-24
Identities = 80/190 (42%), Positives = 97/190 (51%), Gaps = 21/190 (11%)
Query: 1 MDAERMGEPQPGL--NAASPLGGGTRVPERGVGNSGDSVRGGRSEQ------PKARQRRK 52
M A G+ P + P G G G G S G +E+ PK R++R
Sbjct: 150 MSASVSGDRSPRTEDDGVGPRGAHVSALCSGAGGGGGSGPAGVAEEEEEPAAPKPRKKRS 209
Query: 53 PRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDK 112
R FS AQV LERRF QRYLS PER LA++L+LT TQVKIWFQNRRYK KR++
Sbjct: 210 -RAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRRQMAA 268
Query: 113 SLELAGHPLTPRRVAVPVLVRDGK------PCLGPGPGAPAFPSPYSAAVSPYSCYGGYS 166
L LA P ++VAV VLVRD + L P P PS Y PY C G++
Sbjct: 269 DL-LASAP-AAKKVAVKVLVRDDQRQYLPGEVLRPPSLLPLQPSYY----YPYYCLPGWA 322
Query: 167 GAPYGAGYGT 176
+ A GT
Sbjct: 323 LSTCAAAAGT 332
>gi|157743259 H6 family homeobox 3 [Homo sapiens]
Length = 357
Score = 91.3 bits (225), Expect = 6e-19
Identities = 62/155 (40%), Positives = 82/155 (52%), Gaps = 10/155 (6%)
Query: 2 DAERMGEPQPGLNAASPLGGGTRVPERGVGNSGDSVRGGRSEQPK-ARQRRKPRVLFSQA 60
++++ GE PG AS +G P + D +G S + K A +++K R +FS++
Sbjct: 184 ESKKEGEAAPGAAGAS-VGAAAATP-----GAEDWKKGAESPEKKPACRKKKTRTVFSRS 237
Query: 61 QVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKSLELA--G 118
QV LE F +RYLS+ ER LA++L LT TQVKIWFQNRR K KRQ LE A
Sbjct: 238 QVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLA-AELEAANLS 296
Query: 119 HPLTPRRVAVPVLVRDGKPCLGPGPGAPAFPSPYS 153
H R V VP+L + G A P P S
Sbjct: 297 HAAAQRIVRVPILYHENSAAEGAAAAAAGAPVPVS 331
>gi|116805350 homeo box (H6 family) 1 [Homo sapiens]
Length = 348
Score = 89.7 bits (221), Expect = 2e-18
Identities = 72/182 (39%), Positives = 92/182 (50%), Gaps = 34/182 (18%)
Query: 9 PQPGLNAASPLGGGTRVPER-GVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALER 67
P G AS L VP G G V GGR ++K R +FS++QV LE
Sbjct: 172 PAAGTEEASELA---EVPAAAGETRGGVGVGGGR--------KKKTRTVFSRSQVFQLES 220
Query: 68 RFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKSLELAGHPLTP---- 123
F +RYLS+ ER LA++LQLT TQVKIWFQNRR K KRQ + EL L+P
Sbjct: 221 TFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQ---LAAELEAASLSPPGAQ 277
Query: 124 RRVAVPVLVRD--------GKPCLGPGPGAPAFPSP------YSAAVS-PYSCYGGYSGA 168
R V VPVL + G P P P APA P+P +S A++ P + + +
Sbjct: 278 RLVRVPVLYHESPPAAAAAGPPATLPFPLAPAAPAPPPPLLGFSGALAYPLAAFPAAASV 337
Query: 169 PY 170
P+
Sbjct: 338 PF 339
>gi|70608170 H6 family homeobox 2 [Homo sapiens]
Length = 273
Score = 89.0 bits (219), Expect = 3e-18
Identities = 53/116 (45%), Positives = 69/116 (59%), Gaps = 3/116 (2%)
Query: 38 RGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIW 97
R G +E+ ++K R +FS++QV LE F +RYLS+ ER LAS+LQLT TQVK W
Sbjct: 137 RDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTW 196
Query: 98 FQNRRYKCKRQRQDKSLELA--GHPLTPRRVAVPVLVRDGKPCLGPGPGAPAFPSP 151
FQNRR K KRQ LE A H V++P++ RD P P + AFP+P
Sbjct: 197 FQNRRNKWKRQ-LSAELEAANMAHASAQTLVSMPLVFRDSSLLRVPVPRSLAFPAP 251
>gi|19923352 NK3 homeobox 1 [Homo sapiens]
Length = 234
Score = 87.8 bits (216), Expect = 6e-18
Identities = 49/104 (47%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 26 PERGVGN---SGDSVRGG--RSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPER 80
PER +G+ ++ G R Q + +++ R FS QV+ LER+F Q+YLSAPER
Sbjct: 95 PERHLGSYLLDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPER 154
Query: 81 EHLASALQLTSTQVKIWFQNRRYKCKRQRQDKSL-ELAGHPLTP 123
HLA L+LT TQVKIWFQNRRYK KR++ L +L H P
Sbjct: 155 AHLAKNLKLTETQVKIWFQNRRYKTKRKQLSSELGDLEKHSSLP 198
>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
Length = 814
Score = 87.0 bits (214), Expect = 1e-17
Identities = 73/202 (36%), Positives = 91/202 (45%), Gaps = 32/202 (15%)
Query: 9 PQPGLNAASPLGGGTRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERR 68
P P AA+P G GT +G + R K+ + R+ R F+ Q++ALE +
Sbjct: 623 PGPPGGAAAPGGAGTT--PQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENK 680
Query: 69 FKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQR--QDKSLELAGHPLTPRRV 126
FK RYLS ER +LA +L LT TQVKIWFQNRR K K+Q D S G
Sbjct: 681 FKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSAPTGG-------- 732
Query: 127 AVPVLVRDGKPCLGPGPG-------APAFPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYA 179
G P G GPG +P PSP A P +G +G G C A
Sbjct: 733 -------GGGPGPGAGPGTGLPGGLSPLSPSPPMGA--PLGMHGPAGYPAHGPGGLVCAA 783
Query: 180 GAP--SGPAPHTP--LASAGFG 197
P S PA +P L S +G
Sbjct: 784 QLPFLSSPAVLSPFVLGSQTYG 805
>gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]
Length = 653
Score = 87.0 bits (214), Expect = 1e-17
Identities = 73/202 (36%), Positives = 91/202 (45%), Gaps = 32/202 (15%)
Query: 9 PQPGLNAASPLGGGTRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERR 68
P P AA+P G GT +G + R K+ + R+ R F+ Q++ALE +
Sbjct: 58 PGPPGGAAAPGGAGTT--PQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENK 115
Query: 69 FKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQR--QDKSLELAGHPLTPRRV 126
FK RYLS ER +LA +L LT TQVKIWFQNRR K K+Q D S G
Sbjct: 116 FKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSAPTGG-------- 167
Query: 127 AVPVLVRDGKPCLGPGPG-------APAFPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYA 179
G P G GPG +P PSP A P +G +G G C A
Sbjct: 168 -------GGGPGPGAGPGTGLPGGLSPLSPSPPMGA--PLGMHGPAGYPAHGPGGLVCAA 218
Query: 180 GAP--SGPAPHTP--LASAGFG 197
P S PA +P L S +G
Sbjct: 219 QLPFLSSPAVLSPFVLGSQTYG 240
>gi|118582284 msh homeobox 1 [Homo sapiens]
Length = 303
Score = 86.3 bits (212), Expect = 2e-17
Identities = 52/131 (39%), Positives = 72/131 (54%), Gaps = 10/131 (7%)
Query: 46 KARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKC 105
K + RKPR F+ AQ+LALER+F+Q++YLS ER +S+L LT TQVKIWFQNRR K
Sbjct: 168 KHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKA 227
Query: 106 KR--QRQDKSLELAGHPLTPRRVAVPVLVRDGKPCLGPGPGAPAF--PSPYSAAVSP--- 158
KR + + + L++A P+ P G + GA + P+ A P
Sbjct: 228 KRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQRAALPVAP 287
Query: 159 ---YSCYGGYS 166
Y+ + GYS
Sbjct: 288 VGLYTAHVGYS 298
>gi|27886557 msh homeobox 2 [Homo sapiens]
Length = 267
Score = 85.9 bits (211), Expect = 2e-17
Identities = 53/132 (40%), Positives = 75/132 (56%), Gaps = 11/132 (8%)
Query: 46 KARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKC 105
K + RKPR F+ +Q+LALER+F+Q++YLS ER +S+L LT TQVKIWFQNRR K
Sbjct: 138 KHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKA 197
Query: 106 KR--QRQDKSLELAGHPLTPRRVAVPVLVRDGKPCLGPGPGAPAFPS--PYSAAVSPYSC 161
KR + + + L++A P+ P ++P P P A + + P+ V P
Sbjct: 198 KRLQEAELEKLKMAAKPMLPSSFSLPF------PISSPLQAASIYGASYPFHRPVLPIPP 251
Query: 162 YGGYSGAPYGAG 173
G Y+ P G G
Sbjct: 252 VGLYA-TPVGYG 262
>gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]
Length = 411
Score = 85.1 bits (209), Expect = 4e-17
Identities = 73/200 (36%), Positives = 91/200 (45%), Gaps = 33/200 (16%)
Query: 11 PGLNAASPLGGGTRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFK 70
PG AA+P G GT +G + R K+ + R+ R F+ Q++ALE +FK
Sbjct: 223 PG-GAAAPGGAGTT--PQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFK 279
Query: 71 QQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQR--QDKSLELAGHPLTPRRVAV 128
RYLS ER +LA +L LT TQVKIWFQNRR K K+Q D S G
Sbjct: 280 ATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSAPTGG---------- 329
Query: 129 PVLVRDGKPCLGPGPG-------APAFPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGA 181
G P G GPG +P PSP A P +G +G G C A
Sbjct: 330 -----GGGPGPGAGPGTGLPGGLSPLSPSPPMGA--PLGMHGPAGYPAHGPGGLVCAAQL 382
Query: 182 P--SGPAPHTP--LASAGFG 197
P S PA +P L S +G
Sbjct: 383 PFLSSPAVLSPFVLGSQTYG 402
>gi|4758168 distal-less homeobox 2 [Homo sapiens]
Length = 328
Score = 84.3 bits (207), Expect = 7e-17
Identities = 60/167 (35%), Positives = 81/167 (48%), Gaps = 18/167 (10%)
Query: 46 KARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKC 105
K ++ RKPR ++S Q+ AL+RRF++ +YL+ PER LA++L LT TQVKIWFQNRR K
Sbjct: 148 KPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKF 207
Query: 106 KRQRQDKSLELAGHPLTPRRVAVPVLVRDGKPCLGPGPGAPAFPSPYSAAVSPYSCYGGY 165
K+ + + HP PC P APA + V P GG
Sbjct: 208 KKMWKSGEIPSEQHPGASA----------SPPCASPPVSAPA---SWDFGV-PQRMAGG- 252
Query: 166 SGAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGGQNATPQGHLAAT 212
G P G G +G+ A L + + H Q + HL AT
Sbjct: 253 -GGPGSGGSGAGSSGSSPSSAASAFLGNYPWYH--QTSGSASHLQAT 296
>gi|24497515 homeobox A3 isoform b [Homo sapiens]
Length = 285
Score = 82.0 bits (201), Expect = 4e-16
Identities = 59/173 (34%), Positives = 83/173 (47%), Gaps = 12/173 (6%)
Query: 32 NSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTS 91
+SG+S G +S +A +R R ++ AQ++ LE+ F RYL P R +A+ L LT
Sbjct: 16 SSGESCAGDKSPPGQASSKRA-RTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTE 74
Query: 92 TQVKIWFQNRRYKCKRQRQDKSLELAGHPLTPRRVAVPV----LVRDGKPCLGPGPGAPA 147
Q+KIWFQNRR K K+ ++ K + + +P R VP + + P P
Sbjct: 75 RQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQ 134
Query: 148 FPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGG 200
P P+S P Y G A Y A +C AP P P +AG G GG
Sbjct: 135 SPPPFSK--PPQGTY-GLPPASYPASLPSC---APP-PPPQKRYTAAGAGAGG 180
>gi|24497513 homeobox A3 isoform a [Homo sapiens]
Length = 443
Score = 82.0 bits (201), Expect = 4e-16
Identities = 59/173 (34%), Positives = 83/173 (47%), Gaps = 12/173 (6%)
Query: 32 NSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTS 91
+SG+S G +S +A +R R ++ AQ++ LE+ F RYL P R +A+ L LT
Sbjct: 174 SSGESCAGDKSPPGQASSKRA-RTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTE 232
Query: 92 TQVKIWFQNRRYKCKRQRQDKSLELAGHPLTPRRVAVPV----LVRDGKPCLGPGPGAPA 147
Q+KIWFQNRR K K+ ++ K + + +P R VP + + P P
Sbjct: 233 RQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQ 292
Query: 148 FPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGG 200
P P+S P Y G A Y A +C AP P P +AG G GG
Sbjct: 293 SPPPFSK--PPQGTY-GLPPASYPASLPSC---APP-PPPQKRYTAAGAGAGG 338
>gi|13562112 homeobox A3 isoform a [Homo sapiens]
Length = 443
Score = 82.0 bits (201), Expect = 4e-16
Identities = 59/173 (34%), Positives = 83/173 (47%), Gaps = 12/173 (6%)
Query: 32 NSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTS 91
+SG+S G +S +A +R R ++ AQ++ LE+ F RYL P R +A+ L LT
Sbjct: 174 SSGESCAGDKSPPGQASSKRA-RTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTE 232
Query: 92 TQVKIWFQNRRYKCKRQRQDKSLELAGHPLTPRRVAVPV----LVRDGKPCLGPGPGAPA 147
Q+KIWFQNRR K K+ ++ K + + +P R VP + + P P
Sbjct: 233 RQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQ 292
Query: 148 FPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGG 200
P P+S P Y G A Y A +C AP P P +AG G GG
Sbjct: 293 SPPPFSK--PPQGTY-GLPPASYPASLPSC---APP-PPPQKRYTAAGAGAGG 338
>gi|226437602 NK1 homeobox 2 [Homo sapiens]
Length = 310
Score = 79.0 bits (193), Expect = 3e-15
Identities = 62/184 (33%), Positives = 81/184 (44%), Gaps = 19/184 (10%)
Query: 9 PQPGLNAASPLGGGTRVPERGVGNSGDSVRGGRSE-QPKARQRRKPRVLFSQAQVLALER 67
P L + P G P R S S R R +P + R+ R F+ Q++ALE
Sbjct: 121 PAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALEN 180
Query: 68 RFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQR--QDKSLELAGHPLTPRR 125
+F+ RYLS ER +LA +L LT TQVKIWFQNRR K K+Q D + ++ G P
Sbjct: 181 KFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQVGGGAPQP-- 238
Query: 126 VAVPVLVRDGKPCLGPGPGAPAFPSPYSAAVSPYSCYGGYSGA----PYGAGYGTCYAGA 181
G G G G+ P P + + YS A P A + A A
Sbjct: 239 ---------GAAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPSAASF-PLTAAA 288
Query: 182 PSGP 185
P P
Sbjct: 289 PGSP 292
>gi|4885185 distal-less homeobox 3 [Homo sapiens]
Length = 287
Score = 79.0 bits (193), Expect = 3e-15
Identities = 55/145 (37%), Positives = 73/145 (50%), Gaps = 14/145 (9%)
Query: 46 KARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKC 105
K ++ RKPR ++S Q+ AL+RRF++ +YL+ PER LA+ L LT TQVKIWFQNRR K
Sbjct: 125 KPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKF 184
Query: 106 KRQRQDKSLELAGHPLTPRRVAV-----PVLVRDGKPCLGPGPGAPAFPSPYSAAVSPYS 160
K+ ++ + L P +A P L D P P P P PYS
Sbjct: 185 KKLYKNGEVPLEHSPNNSDSMACNSPPSPAL-WDTSSHSTPAPARSQLPPPL-----PYS 238
Query: 161 CYGGYSGAPYGAGYGTCYAGAPSGP 185
Y P + Y +A SGP
Sbjct: 239 ASPSYLDDPTNSWY---HAQNLSGP 260
>gi|64225290 distal-less homeobox 1 isoform 1 [Homo sapiens]
Length = 255
Score = 79.0 bits (193), Expect = 3e-15
Identities = 43/97 (44%), Positives = 58/97 (59%), Gaps = 5/97 (5%)
Query: 46 KARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKC 105
K ++ RKPR ++S Q+ AL RRF+Q +YL+ PER LA++L LT TQVKIWFQN+R K
Sbjct: 124 KGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKF 183
Query: 106 KRQRQDKSLELAGHPLTPRRVAVPVLVRDGKPCLGPG 142
K+ + L G L R + G P + PG
Sbjct: 184 KKLMKQGGAALEGSALANGRA-----LSAGSPPVPPG 215
>gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]
Length = 332
Score = 79.0 bits (193), Expect = 3e-15
Identities = 62/184 (33%), Positives = 81/184 (44%), Gaps = 19/184 (10%)
Query: 9 PQPGLNAASPLGGGTRVPERGVGNSGDSVRGGRSE-QPKARQRRKPRVLFSQAQVLALER 67
P L + P G P R S S R R +P + R+ R F+ Q++ALE
Sbjct: 143 PAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALEN 202
Query: 68 RFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQR--QDKSLELAGHPLTPRR 125
+F+ RYLS ER +LA +L LT TQVKIWFQNRR K K+Q D + ++ G P
Sbjct: 203 KFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQVGGGAPQP-- 260
Query: 126 VAVPVLVRDGKPCLGPGPGAPAFPSPYSAAVSPYSCYGGYSGA----PYGAGYGTCYAGA 181
G G G G+ P P + + YS A P A + A A
Sbjct: 261 ---------GAAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPSAASF-PLTAAA 310
Query: 182 PSGP 185
P P
Sbjct: 311 PGSP 314
>gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]
Length = 332
Score = 79.0 bits (193), Expect = 3e-15
Identities = 62/184 (33%), Positives = 81/184 (44%), Gaps = 19/184 (10%)
Query: 9 PQPGLNAASPLGGGTRVPERGVGNSGDSVRGGRSE-QPKARQRRKPRVLFSQAQVLALER 67
P L + P G P R S S R R +P + R+ R F+ Q++ALE
Sbjct: 143 PAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALEN 202
Query: 68 RFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQR--QDKSLELAGHPLTPRR 125
+F+ RYLS ER +LA +L LT TQVKIWFQNRR K K+Q D + ++ G P
Sbjct: 203 KFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQVGGGAPQP-- 260
Query: 126 VAVPVLVRDGKPCLGPGPGAPAFPSPYSAAVSPYSCYGGYSGA----PYGAGYGTCYAGA 181
G G G G+ P P + + YS A P A + A A
Sbjct: 261 ---------GAAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPSAASF-PLTAAA 310
Query: 182 PSGP 185
P P
Sbjct: 311 PGSP 314
>gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]
Length = 332
Score = 79.0 bits (193), Expect = 3e-15
Identities = 62/184 (33%), Positives = 81/184 (44%), Gaps = 19/184 (10%)
Query: 9 PQPGLNAASPLGGGTRVPERGVGNSGDSVRGGRSE-QPKARQRRKPRVLFSQAQVLALER 67
P L + P G P R S S R R +P + R+ R F+ Q++ALE
Sbjct: 143 PAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALEN 202
Query: 68 RFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQR--QDKSLELAGHPLTPRR 125
+F+ RYLS ER +LA +L LT TQVKIWFQNRR K K+Q D + ++ G P
Sbjct: 203 KFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQVGGGAPQP-- 260
Query: 126 VAVPVLVRDGKPCLGPGPGAPAFPSPYSAAVSPYSCYGGYSGA----PYGAGYGTCYAGA 181
G G G G+ P P + + YS A P A + A A
Sbjct: 261 ---------GAAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPSAASF-PLTAAA 310
Query: 182 PSGP 185
P P
Sbjct: 311 PGSP 314
>gi|147901462 brain specific homeobox [Homo sapiens]
Length = 233
Score = 76.6 bits (187), Expect = 1e-14
Identities = 37/60 (61%), Positives = 46/60 (76%)
Query: 49 QRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQ 108
+RRK R +FS +Q+ LE+RF+ QRYLS PER LA+AL L+ TQVK WFQNRR K K+Q
Sbjct: 109 RRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKHKKQ 168
>gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]
Length = 284
Score = 76.3 bits (186), Expect = 2e-14
Identities = 36/64 (56%), Positives = 49/64 (76%)
Query: 49 QRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQ 108
+R+KPR FS++QVL LERRF +Q+YL++ ER LA AL++T QVK WFQNRR K +RQ
Sbjct: 156 KRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQ 215
Query: 109 RQDK 112
++
Sbjct: 216 TAEE 219
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,940,885
Number of Sequences: 37866
Number of extensions: 671026
Number of successful extensions: 4305
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 298
Number of HSP's successfully gapped in prelim test: 199
Number of HSP's that attempted gapping in prelim test: 3535
Number of HSP's gapped (non-prelim): 882
length of query: 219
length of database: 18,247,518
effective HSP length: 98
effective length of query: 121
effective length of database: 14,536,650
effective search space: 1758934650
effective search space used: 1758934650
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.