Search of human proteins with 210032509

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
         (887 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]        1771   0.0  
gi|210032463 family with sequence similarity 48, member B2 [Homo...  1459   0.0  
gi|239752280 PREDICTED: similar to family with sequence similari...  1364   0.0  
gi|98961135 family with sequence similarity 48, member A isoform...   714   0.0  
gi|8923735 family with sequence similarity 48, member A isoform ...   693   0.0  
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             86   2e-16
gi|19111150 angiomotin isoform 2 [Homo sapiens]                        84   4e-16
gi|166064029 angiomotin isoform 1 [Homo sapiens]                       84   4e-16
gi|163965366 nascent polypeptide-associated complex alpha subuni...    79   2e-14
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    78   3e-14
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    78   3e-14
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ...    78   3e-14
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    78   3e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    72   2e-12
gi|239745807 PREDICTED: keratin associated protein 4-9 [Homo sap...    72   2e-12
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          71   5e-12
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          71   5e-12
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          71   5e-12
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     71   5e-12
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         70   7e-12
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    70   1e-11
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     70   1e-11
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     70   1e-11
gi|7662236 TSC22 domain family, member 2 [Homo sapiens]                69   3e-11
gi|119943102 CREB binding protein isoform b [Homo sapiens]             67   6e-11
gi|119943104 CREB binding protein isoform a [Homo sapiens]             67   6e-11
gi|169211815 PREDICTED: keratin associated protein 4.6 [Homo sap...    66   1e-10
gi|110347459 MYC-associated zinc finger protein isoform 2 [Homo ...    66   2e-10
gi|110347461 MYC-associated zinc finger protein isoform 1 [Homo ...    66   2e-10
gi|117938759 GNAS complex locus XLas [Homo sapiens]                    66   2e-10

>gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
          Length = 887

 Score = 1771 bits (4588), Expect = 0.0
 Identities = 887/887 (100%), Positives = 887/887 (100%)

Query: 1   MDRDLEQALDRAENIIEIAQQRPPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60
           MDRDLEQALDRAENIIEIAQQRPPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS
Sbjct: 1   MDRDLEQALDRAENIIEIAQQRPPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60

Query: 61  NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120
           NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE
Sbjct: 61  NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120

Query: 121 LPPALGDVLDKASVNIFHSGCVIVEVRDYRQSSNMQPPGYQSRHILLRPTMQTLAHDVKM 180
           LPPALGDVLDKASVNIFHSGCVIVEVRDYRQSSNMQPPGYQSRHILLRPTMQTLAHDVKM
Sbjct: 121 LPPALGDVLDKASVNIFHSGCVIVEVRDYRQSSNMQPPGYQSRHILLRPTMQTLAHDVKM 180

Query: 181 MTRDGQKWSQEDKLQLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMKRCLQ 240
           MTRDGQKWSQEDKLQLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMKRCLQ
Sbjct: 181 MTRDGQKWSQEDKLQLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMKRCLQ 240

Query: 241 RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNIAKAGSCVDTWKGRPCDL 300
           RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNIAKAGSCVDTWKGRPCDL
Sbjct: 241 RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNIAKAGSCVDTWKGRPCDL 300

Query: 301 AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFGFALEAGCQAWDTKPSIMQSFND 360
           AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFGFALEAGCQAWDTKPSIMQSFND
Sbjct: 301 AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFGFALEAGCQAWDTKPSIMQSFND 360

Query: 361 PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG 420
           PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG
Sbjct: 361 PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG 420

Query: 421 KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF 480
           KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF
Sbjct: 421 KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF 480

Query: 481 PPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAA 540
           PPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAA
Sbjct: 481 PPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAA 540

Query: 541 AAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQ 600
           AAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQ
Sbjct: 541 AAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQ 600

Query: 601 LRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARP 660
           LRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARP
Sbjct: 601 LRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARP 660

Query: 661 GAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHP 720
           GAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHP
Sbjct: 661 GAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHP 720

Query: 721 PQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQL 780
           PQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQL
Sbjct: 721 PQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQL 780

Query: 781 PSVLRQQQPQPQPPKLQLQPQWQPKPRQEQPQSQQQQPQHIQLQTQQLRVLQQPQHIQLQ 840
           PSVLRQQQPQPQPPKLQLQPQWQPKPRQEQPQSQQQQPQHIQLQTQQLRVLQQPQHIQLQ
Sbjct: 781 PSVLRQQQPQPQPPKLQLQPQWQPKPRQEQPQSQQQQPQHIQLQTQQLRVLQQPQHIQLQ 840

Query: 841 TQQLRVLQQPVFLATGAVQIVQPHPGVQVGSQLVDQRKEGKPTPPAP 887
           TQQLRVLQQPVFLATGAVQIVQPHPGVQVGSQLVDQRKEGKPTPPAP
Sbjct: 841 TQQLRVLQQPVFLATGAVQIVQPHPGVQVGSQLVDQRKEGKPTPPAP 887


>gi|210032463 family with sequence similarity 48, member B2 [Homo
           sapiens]
          Length = 817

 Score = 1459 bits (3778), Expect = 0.0
 Identities = 762/887 (85%), Positives = 772/887 (87%), Gaps = 70/887 (7%)

Query: 1   MDRDLEQALDRAENIIEIAQQRPPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60
           MDRDLEQALDR ENI EIAQQR PRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS
Sbjct: 1   MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60

Query: 61  NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120
           NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE
Sbjct: 61  NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120

Query: 121 LPPALGDVLDKASVNIFHSGCVIVEVRDYRQSSNMQPPGYQSRHILLRPTMQTLAHDVKM 180
           LPPALGDVLDKASVNIFHSGCVIVEVRDYRQSSNMQPPGYQSRHILLRPTMQTLA +VK 
Sbjct: 121 LPPALGDVLDKASVNIFHSGCVIVEVRDYRQSSNMQPPGYQSRHILLRPTMQTLAPEVKT 180

Query: 181 MTRDGQKWSQEDKLQLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMKRCLQ 240
           MTRDG+KWSQEDK  LESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPM++CLQ
Sbjct: 181 MTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMEQCLQ 240

Query: 241 RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNIAKAGSCVDTWKGRPCDL 300
           RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNI KAGSCVDTWKGRPCDL
Sbjct: 241 RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNITKAGSCVDTWKGRPCDL 300

Query: 301 AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFGFALEAGCQAWDTKPSIMQSFND 360
           AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPF  A EAGCQAWDTKP+IMQSFND
Sbjct: 301 AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFRHAWEAGCQAWDTKPNIMQSFND 360

Query: 361 PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG 420
           PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG
Sbjct: 361 PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG 420

Query: 421 KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF 480
           KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF
Sbjct: 421 KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF 480

Query: 481 PPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAA 540
           PPQQAGSPLKRPF              AAA A AAAAPAPA A AAAPALAA        
Sbjct: 481 PPQQAGSPLKRPF-------------PAAAPAVAAAAPAPAPAPAAAPALAA-------- 519

Query: 541 AAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQ 600
                         AA  AAA  AAPSHSQKPSVPLI+ASR  PAA  PT+F+KIAPAIQ
Sbjct: 520 --------------AAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQ 565

Query: 601 LRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARP 660
           +RTGSTGLKA NVEGPV+GAQ LG SFKPVQAPGSGAPAPAGISGS LQSSGGPLPDARP
Sbjct: 566 VRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARP 625

Query: 661 GAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHP 720
           GAVQASSPAPLQFFLNTPEGLRPLT LQVPQG AVLTGPQQQSHQLVSLQQLQQPTAAHP
Sbjct: 626 GAVQASSPAPLQFFLNTPEGLRPLT-LQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHP 684

Query: 721 PQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQL 780
           PQPGPQGS LGLSTQGQAFPAQQLL VN T A SGLQPQPQ AVLSLLGSAQVPQQGVQL
Sbjct: 685 PQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQL 744

Query: 781 PSVLRQQQPQPQPPKLQLQPQWQPKPRQEQPQSQQQQPQHIQLQTQQLRVLQQPQHIQLQ 840
           P VL  QQPQ   P L LQP              Q QPQ IQLQTQ              
Sbjct: 745 PFVL-GQQPQ---PLLLLQP--------------QPQPQQIQLQTQ-------------- 772

Query: 841 TQQLRVLQQPVFLATGAVQIVQPHPGVQVGSQLVDQRKEGKPTPPAP 887
              LRVLQQPVFLATGAVQIVQPHPGVQ GSQLV QRK GKPTPPAP
Sbjct: 773 --PLRVLQQPVFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPPAP 817


>gi|239752280 PREDICTED: similar to family with sequence similarity
           48, member B2 [Homo sapiens]
          Length = 779

 Score = 1364 bits (3530), Expect = 0.0
 Identities = 724/887 (81%), Positives = 734/887 (82%), Gaps = 108/887 (12%)

Query: 1   MDRDLEQALDRAENIIEIAQQRPPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60
           MDRDLEQALDR ENI EIAQQR PRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS
Sbjct: 1   MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60

Query: 61  NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120
           NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE
Sbjct: 61  NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120

Query: 121 LPPALGDVLDKASVNIFHSGCVIVEVRDYRQSSNMQPPGYQSRHILLRPTMQTLAHDVKM 180
           LPPA                                      RHILLRPTMQTLA +VK 
Sbjct: 121 LPPA--------------------------------------RHILLRPTMQTLAPEVKT 142

Query: 181 MTRDGQKWSQEDKLQLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMKRCLQ 240
           MTRDG+KWSQEDK  LESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPM++CLQ
Sbjct: 143 MTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMEQCLQ 202

Query: 241 RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNIAKAGSCVDTWKGRPCDL 300
           RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNI KAGSCVDTWKGRPCDL
Sbjct: 203 RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNITKAGSCVDTWKGRPCDL 262

Query: 301 AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFGFALEAGCQAWDTKPSIMQSFND 360
           AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPF  A EAGCQAWDTKP+IMQSFND
Sbjct: 263 AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFRHAWEAGCQAWDTKPNIMQSFND 322

Query: 361 PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG 420
           PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG
Sbjct: 323 PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG 382

Query: 421 KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF 480
           KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF
Sbjct: 383 KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF 442

Query: 481 PPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAA 540
           PPQQAGSPLKRPF              AAA A AAAAPAPA A AAAPALAA        
Sbjct: 443 PPQQAGSPLKRPF-------------PAAAPAVAAAAPAPAPAPAAAPALAA-------- 481

Query: 541 AAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQ 600
                         AA  AAA  AAPSHSQKPSVPLI+ASR  PAA  PT+F+KIAPAIQ
Sbjct: 482 --------------AAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQ 527

Query: 601 LRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARP 660
           +RTGSTGLKA NVEGPV+GAQ LG SFKPVQAPGSGAPAPAGISGS LQSSGGPLPDARP
Sbjct: 528 VRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARP 587

Query: 661 GAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHP 720
           GAVQASSPAPLQFFLNTPEGLRPLT LQVPQG AVLTGPQQQSHQLVSLQQLQQPTAAHP
Sbjct: 588 GAVQASSPAPLQFFLNTPEGLRPLT-LQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHP 646

Query: 721 PQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQL 780
           PQPGPQGS LGLSTQGQAFPAQQLL VN T A SGLQPQPQ AVLSLLGSAQVPQQGVQL
Sbjct: 647 PQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQL 706

Query: 781 PSVLRQQQPQPQPPKLQLQPQWQPKPRQEQPQSQQQQPQHIQLQTQQLRVLQQPQHIQLQ 840
           P VL  QQPQ   P L LQP              Q QPQ IQLQTQ              
Sbjct: 707 PFVL-GQQPQ---PLLLLQP--------------QPQPQQIQLQTQ-------------- 734

Query: 841 TQQLRVLQQPVFLATGAVQIVQPHPGVQVGSQLVDQRKEGKPTPPAP 887
              LRVLQQPVFLATGAVQIVQPHPGVQ GSQLV QRK GKPTPPAP
Sbjct: 735 --PLRVLQQPVFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPPAP 779


>gi|98961135 family with sequence similarity 48, member A isoform a
           [Homo sapiens]
          Length = 779

 Score =  714 bits (1844), Expect = 0.0
 Identities = 436/895 (48%), Positives = 527/895 (58%), Gaps = 128/895 (14%)

Query: 1   MDRDLEQALDRAENIIEIAQQRPPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60
           M + LE ALDRAE +IE A+QRPP+R+Y     K++ +KLYD+Y+EEC KEPE  ++LR 
Sbjct: 1   MQQALELALDRAEYVIESARQRPPKRKYLSSGRKSVFQKLYDLYIEECEKEPE-VKKLRR 59

Query: 61  NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120
           NVNLLEKLV +E+L CL+VNLYPGN+GYS+ML+ ++GS +ETIRLPYEE  LL+YLDAEE
Sbjct: 60  NVNLLEKLVMQETLSCLVVNLYPGNEGYSLMLRGKNGSDSETIRLPYEEGELLEYLDAEE 119

Query: 121 LPPALGDVLDKASVNIFHSGCVIVEVRDYRQSSNMQPPGYQSRHILLRPTMQTLAHDVKM 180
           LPP L D+L+K+ VNIFH GCVI E+RDYRQSSNM+ PGYQSRHILLRPTMQTL  DV  
Sbjct: 120 LPPILVDLLEKSQVNIFHCGCVIAEIRDYRQSSNMKSPGYQSRHILLRPTMQTLICDVHS 179

Query: 181 MTRDGQKWSQEDKLQLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMKRCLQ 240
           +T D  KW+QEDKL LESQLILATAEPLCLDPS+AV CTANRLLYNKQKMNT PMKRC +
Sbjct: 180 ITSDNHKWTQEDKLLLESQLILATAEPLCLDPSIAVTCTANRLLYNKQKMNTRPMKRCFK 239

Query: 241 RYSWPSVKPQQEQSDCPPPPELRVSTSGQK-EERKVGQPCELNIAKAGSCVDTWKGRPCD 299
           RYS  S+  QQ+ S CPPPP+LR+    QK +ERK GQ  +L I+KAG+CVD WK  PC+
Sbjct: 240 RYSRSSLNRQQDLSHCPPPPQLRLLDFLQKRKERKAGQHYDLKISKAGNCVDMWKRSPCN 299

Query: 300 LAVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFGFALEAGCQAWDTKPSIMQSFN 359
           LA+PSEVDVEK AK  +S+ + D Q  VWPA +V+D + F  EAG Q   TK +I+QS  
Sbjct: 300 LAIPSEVDVEKYAKVEKSIKSDDSQPTVWPAHDVKDDYVFECEAGTQYQKTKLTILQSLG 359

Query: 360 DPLLCGKIRPRKKARQK-SQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKG 418
           DPL  GKI+P K   +  SQ SP     DDHS     GS+TDA R V+Q QE VQ++ K 
Sbjct: 360 DPLYYGKIQPCKADEESDSQMSPSHSSTDDHSNWFIIGSKTDAERVVNQYQELVQNEAKC 419

Query: 419 PGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGN 478
           P KMSHSSSG AS+SQ+S  K  +Q + V VQSSV GKG KH PP  +LPSSSG  SSGN
Sbjct: 420 PVKMSHSSSGSASLSQVSPGKETDQTETVSVQSSVLGKGVKHRPPPIKLPSSSGNSSSGN 479

Query: 479 SFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPAL 538
            F PQQ  S LK P                         P P+   ++ P  ++     +
Sbjct: 480 YFTPQQTSSFLKSP------------------------TPPPSSKPSSIPRKSSVDLNQV 515

Query: 539 AAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPA 598
           +  +  A +PA                 S SQ+ +                        A
Sbjct: 516 SMLSPAALSPA-----------------SSSQRTT------------------------A 534

Query: 599 IQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDA 658
            Q+   S GL  INV G V GAQAL S   P+    +GA  PAGI+ S L  SGG LP+A
Sbjct: 535 TQVMANSAGLNFINVVGSVCGAQALMSGSNPMLGCNTGAITPAGINLSGLLPSGGLLPNA 594

Query: 659 RPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSL--QQLQQPT 716
            P A+QA+S A + F L     LRPL LLQ+P GS +    QQQ  QL     QQ QQPT
Sbjct: 595 LPSAMQAASQAGVPFGLKNTSSLRPLNLLQLPGGSLIFNTLQQQQQQLSQFTPQQPQQPT 654

Query: 717 AAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQ---- 772
              P QPG QGS  G ++Q QA  AQQ   +N T   S +  Q Q AVLS LGSA+    
Sbjct: 655 TCSPQQPGEQGSEQGSTSQEQALSAQQAAVINLTGVGSFM--QSQAAVLSQLGSAENRPE 712

Query: 773 --VPQQGVQLPSVLRQQQPQPQPPKLQLQPQWQPKPRQEQPQSQQQQPQHIQLQTQQLRV 830
             +PQQ  QL S  +QQQ Q                                        
Sbjct: 713 QSLPQQRFQLSSAFQQQQQQ---------------------------------------- 732

Query: 831 LQQPQHIQLQTQQLRVLQQPVFLATGAVQIVQPHPGVQVGSQLVDQRKEGKPTPP 885
                      QQLR LQ  + +A  A Q  Q H     GSQ   + K G PT P
Sbjct: 733 ----------IQQLRFLQHQMAMAAAAAQTAQLHHHRHTGSQSKSKMKRGTPTTP 777


>gi|8923735 family with sequence similarity 48, member A isoform b
           [Homo sapiens]
          Length = 733

 Score =  693 bits (1789), Expect = 0.0
 Identities = 400/763 (52%), Positives = 484/763 (63%), Gaps = 69/763 (9%)

Query: 1   MDRDLEQALDRAENIIEIAQQRPPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60
           M + LE ALDRAE +IE A+QRPP+R+Y     K++ +KLYD+Y+EEC KEPE  Q+LR 
Sbjct: 1   MQQALELALDRAEYVIESARQRPPKRKYLSSGRKSVFQKLYDLYIEECEKEPEVKQKLRR 60

Query: 61  NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120
           NVNLLEKLV +E+L CL+VNLYPGN+GYS+ML+ ++GS +ETIRLPYEE  LL+YLDAEE
Sbjct: 61  NVNLLEKLVMQETLSCLVVNLYPGNEGYSLMLRGKNGSDSETIRLPYEEGELLEYLDAEE 120

Query: 121 LPPALGDVLDKASVNIFHSGCVIVEVRDYRQSSNMQPPGYQSRHILLRPTMQTLAHDVKM 180
           LPP L D+L+K+ VNIFH GCVI E+RDYRQSSNM+ PGYQSRHILLRPTMQTL  DV  
Sbjct: 121 LPPILVDLLEKSQVNIFHCGCVIAEIRDYRQSSNMKSPGYQSRHILLRPTMQTLICDVHS 180

Query: 181 MTRDGQKWSQEDKLQLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMKRCLQ 240
           +T D  KW+QEDKL LESQLILATAEPLCLDPS+AV CTANRLLYNKQKMNT PMKRC +
Sbjct: 181 ITSDNHKWTQEDKLLLESQLILATAEPLCLDPSIAVTCTANRLLYNKQKMNTRPMKRCFK 240

Query: 241 RYSWPSVKPQQEQSDCPPPPELRVSTSGQK-EERKVGQPCELNIAKAGSCVDTWKGRPCD 299
           RYS  S+  QQ+ S CPPPP+LR+    QK +ERK GQ  +L I+KAG+CVD WK  PC+
Sbjct: 241 RYSRSSLNRQQDLSHCPPPPQLRLLDFLQKRKERKAGQHYDLKISKAGNCVDMWKRSPCN 300

Query: 300 LAVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFGFALEAGCQAWDTKPSIMQSFN 359
           LA+PSEVDVEK AK  +S+ + D Q  VWPA +V+D + F  EAG Q   TK +I+QS  
Sbjct: 301 LAIPSEVDVEKYAKVEKSIKSDDSQPTVWPAHDVKDDYVFECEAGTQYQKTKLTILQSLG 360

Query: 360 DPLLCGKIRPRKKARQK-SQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKG 418
           DPL  GKI+P K   +  SQ SP     DDHS     GS+TDA R V+Q QE VQ++ K 
Sbjct: 361 DPLYYGKIQPCKADEESDSQMSPSHSSTDDHSNWFIIGSKTDAERVVNQYQELVQNEAKC 420

Query: 419 PGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGN 478
           P KMSHSSSG AS+SQ+S  K  +Q + V VQSSV GKG KH PP  +LPSSSG  SSGN
Sbjct: 421 PVKMSHSSSGSASLSQVSPGKETDQTETVSVQSSVLGKGVKHRPPPIKLPSSSGNSSSGN 480

Query: 479 SFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPAL 538
            F PQQ  S LK P                         P P+   ++ P  ++     +
Sbjct: 481 YFTPQQTSSFLKSP------------------------TPPPSSKPSSIPRKSSVDLNQV 516

Query: 539 AAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPA 598
           +  +  A +PA                 S SQ+ +                        A
Sbjct: 517 SMLSPAALSPA-----------------SSSQRTT------------------------A 535

Query: 599 IQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDA 658
            Q+   S GL  INV G V GAQAL S   P+    +GA  PAGI+ S L  SGG LP+A
Sbjct: 536 TQVMANSAGLNFINVVGSVCGAQALMSGSNPMLGCNTGAITPAGINLSGLLPSGGLLPNA 595

Query: 659 RPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSL--QQLQQPT 716
            P A+QA+S A + F L     LRPL LLQ+P GS +    QQQ  QL     QQ QQPT
Sbjct: 596 LPSAMQAASQAGVPFGLKNTSSLRPLNLLQLPGGSLIFNTLQQQQQQLSQFTPQQPQQPT 655

Query: 717 AAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQ 759
              P QPG QGS  G ++Q QA  AQQ   +N T   S +Q Q
Sbjct: 656 TCSPQQPGEQGSEQGSTSQEQALSAQQAAVINLTGVGSFMQSQ 698


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 157/625 (25%), Positives = 243/625 (38%), Gaps = 89/625 (14%)

Query: 231  NTDPMKRCLQRYSWPSVKP--QQEQSDCPPPPELRVSTSGQKEERKVGQPCE------LN 282
            N  P KR + + S+ S +P  +Q +     PP+   + SG + ER+ G P +       +
Sbjct: 1530 NVLPPKREIAKRSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKSGKRGPFD 1589

Query: 283  IAKAGSC-VDTWKGRPC--DLAVPSEVDVEKLAKGYQSVTAADPQL-PVWPAQEVEDPFG 338
               AG+  VD   G        VP+    +K +K        DP+  P  P ++V+    
Sbjct: 1590 DQPAGTTGVDLINGSSAHHQEGVPNGTG-QKNSKDSTGKKREDPKPGPKKPKEKVDALSQ 1648

Query: 339  FALE--AGCQAWDTKPSI------MQSFNDPLLCGKIRPRKKARQKSQKSPWQPFPDDHS 390
            F L   A     D  P +        + ND      +   KK +++ Q    +   +   
Sbjct: 1649 FDLNNYASVVIIDDHPEVTVIEDPQSNLNDDGFTEVVS--KKQQKRLQDEERRKKEEQVI 1706

Query: 391  ACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQ 450
                  +  + GR+ +       +K +  G     SS  ASV  L+S   P    P    
Sbjct: 1707 QVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQAQSS--ASVPPLASAPLP----PSTSA 1760

Query: 451  SSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAG-------SPLKRPFSAAAAIAAA- 502
            S  +      P   T +P+S+      ++  P  A        SPL  P SA+A+++A+ 
Sbjct: 1761 SVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLA-PVSASASVSASV 1819

Query: 503  -----AAAAAAAAAAAAAAAPAPALAAAAAPA----LAAAAAPALAAAAAPAPAPAAAPA 553
                 AAA  +++A A+A AP P LA+ + PA    LA+A+ P LA+A A   AP  APA
Sbjct: 1820 PASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPA 1879

Query: 554  VA--AAPAAAASAAPSHSQKPSVPLIQASRPCPAAQP-PTKFIKIAPAIQLRTGSTGLKA 610
             +  AAP   A   P+ +   SVPL  AS   PA  P P      AP    +T +   K 
Sbjct: 1880 ASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTHK- 1938

Query: 611  INVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGAVQASSPAP 670
                 PVQ      S       P    P+    +G+D  +SG  +   +       S   
Sbjct: 1939 -----PVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQ-------SHGT 1986

Query: 671  LQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQG--- 727
            L   L   +   P  L  + +    ++ PQ  S     +    +P  +    P  +G   
Sbjct: 1987 LTAELWDNKVAPPAVLNDISKKLGPISPPQPPS-----VSAWNKPLTSFGSAPSSEGAKN 2041

Query: 728  ---SALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQLPSVL 784
               S L + T    F A          A +G + +  P VLS   + ++P+     P   
Sbjct: 2042 GQESGLEIGTDTIQFGAP---------ASNGNENEVVP-VLSEKSADKIPE-----PKEQ 2086

Query: 785  RQQQPQPQPPKLQLQPQWQPKPRQE 809
            RQ+QP+  P K Q  P   P   +E
Sbjct: 2087 RQKQPRAGPIKAQKLPDLSPVENKE 2111



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 110/456 (24%), Positives = 178/456 (39%), Gaps = 49/456 (10%)

Query: 366  KIRPR---KKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKM 422
            K+ PR   K+A    Q       P   SA L P +      + S    +  + V      
Sbjct: 1724 KLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSA 1783

Query: 423  SHSSSGPASVSQLSSWKTPEQP-DPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFP 481
               +S  A V   +S   P  P  PV   +SVS            +P+S+   +  +S  
Sbjct: 1784 PVPASTLAPVLASTSAPVPASPLAPVSASASVSAS----------VPASTSAAAITSSSA 1833

Query: 482  PQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAA 541
            P  A +P   P  A+ +  A+    A+A+    A+A A   A   APA ++ AAP + A 
Sbjct: 1834 P--ASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAP 1891

Query: 542  AAPAPAPAA----APAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIA- 596
              PA AP A    APA A+APA A +   + +  P  P    ++     Q P +    + 
Sbjct: 1892 TIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSS 1951

Query: 597  ----PAIQLRTGST--GLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQS 650
                P+I+L +  T  G   +     +Q  Q+ G+    +       PA      +D+  
Sbjct: 1952 KQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVL----NDISK 2007

Query: 651  SGGPLPDARPGAVQASSPAPLQFFLNTP--EGLR--PLTLLQVPQGSAVLTGPQQQSHQL 706
              GP+   +P +V A +  PL  F + P  EG +    + L++   +     P    ++ 
Sbjct: 2008 KLGPISPPQPPSVSAWN-KPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNEN 2066

Query: 707  VSLQQLQQPTAAHPPQPGPQGSALGLSTQGQAFP--AQQLLKVNPTRARSGLQPQPQPAV 764
              +  L + +A   P+P  Q        Q +A P  AQ+L  ++P   +   +P P    
Sbjct: 2067 EVVPVLSEKSADKIPEPKEQ-----RQKQPRAGPIKAQKLPDLSPVENKEH-KPGPIGKE 2120

Query: 765  LSLLG-----SAQVPQQGVQLPSVLRQQQPQPQPPK 795
             SL       + QV  +G + PS    +   P   K
Sbjct: 2121 RSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTK 2156



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 83/366 (22%), Positives = 117/366 (31%), Gaps = 101/366 (27%)

Query: 523  AAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRP 582
            A     A ++A+ P LA+A  P    A+ PA  +AP  A       S          S P
Sbjct: 1734 ATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPAS---------TSAP 1784

Query: 583  CPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGS-GAPAPA 641
             PA+        +AP +            +   PV       S   PV A  S  A  PA
Sbjct: 1785 VPAST-------LAPVLA-----------STSAPVPA-----SPLAPVSASASVSASVPA 1821

Query: 642  GISGSDLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQ 701
              S + + SS  P          A +P P+   ++TP  +  L    +P  ++ L     
Sbjct: 1822 STSAAAITSSSAP--------ASAPAPTPILASVSTPASVTILASASIPILASALAS--- 1870

Query: 702  QSHQLVSLQQLQQPTAAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQ 761
                          T+A  P P     A  + T     PA       P    S   P P 
Sbjct: 1871 --------------TSAPTPAPAASSPAAPVIT-APTIPASAPTASVPLAPASASAPAPA 1915

Query: 762  PAVLSLLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQLQPQWQPKPRQEQPQSQQQQPQHI 821
            P  +S                      P P PP               Q Q+Q  +P   
Sbjct: 1916 PTPVSA---------------------PNPAPPA------------PAQTQAQTHKPVQN 1942

Query: 822  QLQTQQLRVLQQPQHIQLQTQQLRVLQQPVFLATG-AVQIVQPHPGVQVGSQLVDQRKEG 880
             LQT      Q P  I+L + Q        ++A+G ++Q  Q H        L  +  + 
Sbjct: 1943 PLQTTSQSSKQPPPSIRLPSAQ--TPNGTDYVASGKSIQTPQSH------GTLTAELWDN 1994

Query: 881  KPTPPA 886
            K  PPA
Sbjct: 1995 KVAPPA 2000


>gi|19111150 angiomotin isoform 2 [Homo sapiens]
          Length = 675

 Score = 84.3 bits (207), Expect = 4e-16
 Identities = 103/320 (32%), Positives = 129/320 (40%), Gaps = 85/320 (26%)

Query: 378 QKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLS- 436
           Q+S  +P   +  +C+RP        ++S A         G G +SHSS+   S      
Sbjct: 358 QRSRKEPSKTEQLSCMRPAKSL---MSISNA---------GSGLLSHSSTLTGSPIMEEK 405

Query: 437 ----SWK---------------TPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSG 477
               SWK                P  P PV              PP T L S+  K  S 
Sbjct: 406 RDDKSWKGSLGILLGGDYRAEYVPSTPSPV--------------PPSTPLLSAHSKTGSR 451

Query: 478 NSFPPQQAGSPLKRPFSAAA-AIAAAAAAAAAAAAAAAAAAPAPALAAAAAP-ALAAAAA 535
           +     + G+   +  + A  ++ A  AAAA AAA  A AA       AAAP A+AAAAA
Sbjct: 452 DCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAA 511

Query: 536 PALAAAAAPAPAPAAAPAVAAAPA------AAASAAPSHSQKPSVPLIQASRPCPAAQPP 589
           P  AAAAAP+PA AAA A A +PA      AAAS A + +  PS     A +  PAA  P
Sbjct: 512 P--AAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAP 569

Query: 590 TKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQ 649
                 APA+           + V  P   A A  S+    QAP S APA A        
Sbjct: 570 VP----APAL-----------VPVPAP---AAAQASAPAQTQAPTS-APAVAPT------ 604

Query: 650 SSGGPLPDARPGAVQASSPA 669
               P P   P   QA  PA
Sbjct: 605 ----PAPTPTPAVAQAEVPA 620



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 65/218 (29%), Positives = 92/218 (42%), Gaps = 17/218 (7%)

Query: 362 LLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGK 421
           LL G  R        S   P  P    HS        T   R     + +  + +  P  
Sbjct: 418 LLGGDYRAEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAP 477

Query: 422 MSHSSSGPASVSQLSSWKTPE-QPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF 480
           ++ +++  A  +  ++  T      PV V ++ +      P P T   +++         
Sbjct: 478 VAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAA--------- 528

Query: 481 PPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPAL-AAAAAPALAAAAAPALA 539
               A SP       AAA  A+AAA A +AAAAAA   APA  A   APAL    APA A
Sbjct: 529 ----AVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAA 584

Query: 540 AAAAPA--PAPAAAPAVAAAPAAAASAAPSHSQKPSVP 575
            A+APA   AP +APAVA  PA   + A + ++ P+ P
Sbjct: 585 QASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASP 622


>gi|166064029 angiomotin isoform 1 [Homo sapiens]
          Length = 1084

 Score = 84.3 bits (207), Expect = 4e-16
 Identities = 103/320 (32%), Positives = 129/320 (40%), Gaps = 85/320 (26%)

Query: 378  QKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLS- 436
            Q+S  +P   +  +C+RP        ++S A         G G +SHSS+   S      
Sbjct: 767  QRSRKEPSKTEQLSCMRPAKSL---MSISNA---------GSGLLSHSSTLTGSPIMEEK 814

Query: 437  ----SWK---------------TPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSG 477
                SWK                P  P PV              PP T L S+  K  S 
Sbjct: 815  RDDKSWKGSLGILLGGDYRAEYVPSTPSPV--------------PPSTPLLSAHSKTGSR 860

Query: 478  NSFPPQQAGSPLKRPFSAAA-AIAAAAAAAAAAAAAAAAAAPAPALAAAAAP-ALAAAAA 535
            +     + G+   +  + A  ++ A  AAAA AAA  A AA       AAAP A+AAAAA
Sbjct: 861  DCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAA 920

Query: 536  PALAAAAAPAPAPAAAPAVAAAPA------AAASAAPSHSQKPSVPLIQASRPCPAAQPP 589
            P  AAAAAP+PA AAA A A +PA      AAAS A + +  PS     A +  PAA  P
Sbjct: 921  P--AAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAP 978

Query: 590  TKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQ 649
                  APA+           + V  P   A A  S+    QAP S APA A        
Sbjct: 979  VP----APAL-----------VPVPAP---AAAQASAPAQTQAPTS-APAVAPT------ 1013

Query: 650  SSGGPLPDARPGAVQASSPA 669
                P P   P   QA  PA
Sbjct: 1014 ----PAPTPTPAVAQAEVPA 1029



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 65/218 (29%), Positives = 92/218 (42%), Gaps = 17/218 (7%)

Query: 362  LLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGK 421
            LL G  R        S   P  P    HS        T   R     + +  + +  P  
Sbjct: 827  LLGGDYRAEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAP 886

Query: 422  MSHSSSGPASVSQLSSWKTPE-QPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF 480
            ++ +++  A  +  ++  T      PV V ++ +      P P T   +++         
Sbjct: 887  VAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAA--------- 937

Query: 481  PPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPAL-AAAAAPALAAAAAPALA 539
                A SP       AAA  A+AAA A +AAAAAA   APA  A   APAL    APA A
Sbjct: 938  ----AVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAA 993

Query: 540  AAAAPA--PAPAAAPAVAAAPAAAASAAPSHSQKPSVP 575
             A+APA   AP +APAVA  PA   + A + ++ P+ P
Sbjct: 994  QASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASP 1031



 Score = 37.0 bits (84), Expect = 0.081
 Identities = 66/255 (25%), Positives = 90/255 (35%), Gaps = 52/255 (20%)

Query: 629 PVQAPGSGAPAPAGI-----SGSDLQSSGGPLPDARP-GAVQASSPAPLQFFLNTPEGLR 682
           PV +     P P  +     S S+   + GPLP+      ++   P P   F   P    
Sbjct: 193 PVTSAPLSPPQPNDLYKNPTSSSEFYKAQGPLPNQHSLKGMEHRGPPPEYPFKGMP---- 248

Query: 683 PLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAA--------HPPQPGPQGSALGLST 734
                  PQ  +V+  PQ+  H   S  +L QP           HPP+            
Sbjct: 249 -------PQ--SVVCKPQEPGH-FYSEHRLNQPGRTEGQLMRYQHPPE------------ 286

Query: 735 QGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQLPSVLRQQQPQPQPP 794
            G A PAQ +    P  AR+  QP    + L+  GS  + Q     PS        P  P
Sbjct: 287 YGAARPAQDISL--PLSARNS-QPHSPTSSLTSGGSLPLLQSP---PSTRLSPARHPLVP 340

Query: 795 KLQLQPQWQPKPRQEQPQSQQQQPQHIQL------QTQQLRVLQQPQHIQLQTQQLRVLQ 848
                    P+P+Q    +Q  Q  H +L      Q QQ +  Q   H   Q QQ +  Q
Sbjct: 341 NQGDHSAHLPRPQQHFLPNQAHQGDHYRLSQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQ 400

Query: 849 QPVFLATGAVQIVQP 863
           Q    A  A+   QP
Sbjct: 401 QQPGEAYSAMPRAQP 415


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 107/442 (24%), Positives = 140/442 (31%), Gaps = 55/442 (12%)

Query: 417  KGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISS 476
            +GP   +   +   S++  S  K    P P  + +S S KG   PP  T      G  + 
Sbjct: 898  EGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATP 957

Query: 477  GNSF--------PPQQAGSPLK-RPFSAAAAIAA---------AAAAAAAAAAAAAAAAP 518
               +        PP   G P    P  A    AA         A  +   A    A   P
Sbjct: 958  SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP 1017

Query: 519  APALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQ 578
            +P  + AA P    A+ P  A   +P  +PAA P    AP   A+  PS    P+ P ++
Sbjct: 1018 SPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLK 1077

Query: 579  ASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAP 638
             +   PAA PP+   K  PA     G+    A     P  G             P  GAP
Sbjct: 1078 GAPTPPAATPPSP--KGGPATPSPKGAPMPPAATPPSPKGGL---------ATPPHKGAP 1126

Query: 639  -APAGISGSDLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQG----- 692
              PA    S       P P   P    A+ P+P       P    P T    P       
Sbjct: 1127 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1186

Query: 693  ---------SAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQG-----SALGLSTQGQA 738
                     +     P      L +      PT      P P+G     S  G  T   A
Sbjct: 1187 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1246

Query: 739  FPAQQLLKVNPTRARSGLQPQPQPAVLSLL--GSAQVPQQGVQLPSVLRQQQPQPQPPKL 796
             P     K  P        P P  A    L  G A  P +G   P+V+    P P+    
Sbjct: 1247 TPPSP--KGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV--TPPSPKGGPA 1302

Query: 797  QLQPQWQPKPRQEQPQSQQQQP 818
               P+  P P    P S +  P
Sbjct: 1303 TSPPKGAPTPPAATPPSPKGSP 1324



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 100/404 (24%), Positives = 155/404 (38%), Gaps = 45/404 (11%)

Query: 411  SVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSS 470
            SV  + K P     S+     +  LSS  +P +   +  ++S+S +G K  P  T  P+ 
Sbjct: 800  SVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFL-PENSLSFQGSKDSPATTHSPTP 858

Query: 471  SGKISS------------GNSFPPQQAGSP--LKRPF-----SAAAAIAAAAAAAAAAAA 511
                 +            G + PP++  +P  +  PF     +  A   A A +  +++ 
Sbjct: 859  PSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSP 918

Query: 512  AAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQK 571
              A A PAP     A+P+   A  P  A   +P   P A P+   AP   A+  PS    
Sbjct: 919  KKARATPAPK-GIPASPSPKGAPTPPAATPPSPKGGP-ATPSPKWAPTPPAATPPSPKGG 976

Query: 572  PSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQAL-----GSS 626
            P+ P  + +   PAA PP+   K  PA     G+    A+    P +G+ A      G+S
Sbjct: 977  PATPSPKGAPTPPAATPPSP--KGGPATPSPKGAPTPPAVTPPSP-KGSPAATPFPKGAS 1033

Query: 627  FKPVQAPGS--GAPAPAGISGSDLQSSGGPLPDARPGAVQAS---SPAPLQFFLNTPEGL 681
              P   P S  G+PA   +      +    LP  + G    S   +P P      +P+G 
Sbjct: 1034 TPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG- 1092

Query: 682  RPLTLLQVPQGSAV--LTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSALGLSTQGQAF 739
             P T    P+G+ +     P      L +      PT      P P+G   GL+T     
Sbjct: 1093 GPAT--PSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG---GLATPPPK- 1146

Query: 740  PAQQLLKVNPTRARSGL-QPQPQPAVLSLLGSAQVPQQGVQLPS 782
             A       P   + GL  P P+ A  +   +   P+ G+  PS
Sbjct: 1147 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPS 1190



 Score = 60.5 bits (145), Expect = 7e-09
 Identities = 70/287 (24%), Positives = 99/287 (34%), Gaps = 15/287 (5%)

Query: 444  PDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAA 503
            P P    ++ S KG    P  T  PS  G +++     P   G+P     +  +     A
Sbjct: 1203 PSPKGGLATPSPKGAPTTPAATP-PSPKGGLAT-----PSPKGAPTTPAATPPSPKGGPA 1256

Query: 504  AAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAAS 563
                  A    AA P       A P    A  PA+    +P   PA +P    AP   A+
Sbjct: 1257 TPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPP-KGAPTPPAA 1315

Query: 564  AAPSHSQKPSVPLIQASRPCPAAQPPT-KFIKIAPAIQLRTGSTGLKAINVEGPVQGAQA 622
              PS    P  P  + +   PA  PP+ K     PA    +        + EGP   A  
Sbjct: 1316 TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT 1375

Query: 623  LGSSFKPVQAP-----GSGAPAPAGISGSDLQSSGGPLPDARPGAVQASSPAPLQFFLNT 677
                  P   P     G   P+P G   S       P         +  +  P +  L T
Sbjct: 1376 PSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDL-T 1434

Query: 678  PEGLRPLTLLQVPQGSAVLTGPQQQSHQ-LVSLQQLQQPTAAHPPQP 723
            P  + P++L + P  SA   GP   S +   +L  +  P+   PP P
Sbjct: 1435 PPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAP 1481



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 88/368 (23%), Positives = 124/368 (33%), Gaps = 68/368 (18%)

Query: 419  PGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSS--VSGKGEKHPPPRTQLPSSSGKISS 476
            P   + S  G  +++  S  + P  P P    +S  V     K  P        +   S 
Sbjct: 1371 PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSK 1430

Query: 477  GNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAP 536
            G+  PP      LK+         A A +A     A  ++   P L A   P+     AP
Sbjct: 1431 GDLTPPAVTPVSLKK---------APATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAP 1481

Query: 537  A-LAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKI 595
              +A +++P  APA  PA   AP   A    S  + P+ P   +SR  P A   T   K 
Sbjct: 1482 KQVATSSSPKKAPAT-PAPMGAPTLPAVIPSSPKEVPATP---SSRRDPIAPTATLLSKK 1537

Query: 596  APAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPL 655
             PA                                 AP      PA    S  ++   P 
Sbjct: 1538 TPA-------------------------------TLAPKEALIPPAMTVPSPKKTPAIPT 1566

Query: 656  PDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQP 715
            P   P A  +S  A      ++P  + P T    P    +L  P   S    S ++   P
Sbjct: 1567 PKEAP-ATPSSKEA------SSPPAVTPSTYKGAPSPKELLIPPAVTS---PSPKEAPTP 1616

Query: 716  TAAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQP-QPAVLSLLGSAQVP 774
             A  PP P           +G A PA +    +P    S L+  P  PA ++    A VP
Sbjct: 1617 PAVTPPSP----------EKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVP 1666

Query: 775  QQGVQLPS 782
            Q    LP+
Sbjct: 1667 QASKGLPA 1674



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 123/533 (23%), Positives = 181/533 (33%), Gaps = 101/533 (18%)

Query: 378  QKSPWQPFPDDHSACLRPGSETD-AGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLS 436
            +K+P  P   + +A    G  T  A   VS  +    S  KG G  + SS G  ++  ++
Sbjct: 1413 KKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG-GPATPSSKGDPTLPAVT 1471

Query: 437  SWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKR--PFS 494
                 E P P  V +S S K     P     P+    I S    P +   +P  R  P +
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSS---PKEVPATPSSRRDPIA 1528

Query: 495  AAAAIAAAAAAAAAAAAAA----AAAAPAPALAAAAAPALAAAAAPALAAAAAP------ 544
              A + +    A  A   A    A   P+P    A      A A P+   A++P      
Sbjct: 1529 PTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPS 1588

Query: 545  ----APAP--------AAAPAVAAAPAAAASAAPSHSQKPSVP----------------- 575
                AP+P          +P+   AP   A   PS  + P+ P                 
Sbjct: 1589 TYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLK 1648

Query: 576  ----------------LIQASRPCPAAQPPT--KFIKIAPAIQ--------LRTGSTGLK 609
                            + QAS+  PA + PT  K + +APA +         R G    K
Sbjct: 1649 DSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKK 1708

Query: 610  AINVEGPV-QGAQALGSSFKPVQ--APGSGAPAPAGIS----GSDL-QSSGGPLPDARPG 661
            +     P+     A   S  P+   AP    P     S    G D   S  GPL      
Sbjct: 1709 SSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESK 1768

Query: 662  AVQASSPAPLQFFLNTPEGLR-------PLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQ 714
            A    + A  +  L  PE          P++L   P  S V T P +Q   L S   L  
Sbjct: 1769 ASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAP--SPVPTLPPKQQF-LPSSPGLVL 1825

Query: 715  PTAAHPPQPGPQGSALGL---STQGQAFPAQQLLKVNPTRARSGLQ-PQP---QPAVLSL 767
             + + P  P  +   L L          P Q +L   PT   +G+  P P   QP   + 
Sbjct: 1826 ESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNN 1885

Query: 768  LGSAQVPQQGVQLPSVLRQQQPQPQPPKLQL----QPQWQPKPRQEQPQSQQQ 816
             GS         +P +  Q   Q    + QL    +   +P  + +Q +S+++
Sbjct: 1886 KGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKK 1938



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 43/162 (26%), Positives = 66/162 (40%), Gaps = 19/162 (11%)

Query: 449 VQSSVSGKGEKHPPPRT----QLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAA 504
           V +++   G   PPP +    Q P S+   +S    P   A +PL+ PF  +++  A   
Sbjct: 34  VTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPL 93

Query: 505 AAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAP---APAAAPAVAAAPAAA 561
             A  A         P ++    PA  A A+P +A      P   AP A  A+A      
Sbjct: 94  GTAPEAPTFLPNLIGPPIS----PAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQK 149

Query: 562 ASAAPSH--SQKPSV------PLIQASRPCPAAQPPTKFIKI 595
           +SA P +  +  PSV       +I  S P   ++P T   K+
Sbjct: 150 SSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKV 191



 Score = 37.4 bits (85), Expect = 0.062
 Identities = 71/324 (21%), Positives = 102/324 (31%), Gaps = 41/324 (12%)

Query: 506 AAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAA 565
           A     A     P P    A  P  +A +  A      P   P  +PA    P +AA+ A
Sbjct: 5   ATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQA 64

Query: 566 ---PSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQA 622
              PS S   S PL     P P +   T       A+ L T          E P      
Sbjct: 65  SPFPSPSTIASTPL---EVPFPQSSSGT-------ALPLGTAP--------EAPTFLPNL 106

Query: 623 LGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLR 682
           +G    P     +       + G+   S+   L    P +VQ SS  P     + P    
Sbjct: 107 IGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPP---- 162

Query: 683 PLTLLQVPQGSAV-LTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSALGLSTQGQAFPA 741
             ++     GS + L+ P   S    +L ++  P+   P   G       +ST     P 
Sbjct: 163 --SVAVAESGSVITLSAPIAPSEPKTNLNKV--PSEVVPNPKGTPSPPCIVST----VPY 214

Query: 742 QQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGV-------QLPSVLRQQQPQPQPP 794
             +  +   ++     PQ  P     + S QV    +       Q P  L  + P   P 
Sbjct: 215 HCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPA 274

Query: 795 KLQLQPQWQPKPRQEQPQSQQQQP 818
            L L  Q  P     Q  +    P
Sbjct: 275 ALSLSTQSLPVVTSSQKTAGPNTP 298



 Score = 30.0 bits (66), Expect = 9.9
 Identities = 60/273 (21%), Positives = 94/273 (34%), Gaps = 27/273 (9%)

Query: 482 PQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAA 541
           PQ        P S+A ++ AA            + AP     +AA  A    +   +A+ 
Sbjct: 17  PQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIAST 76

Query: 542 AAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQAS-------------RPCPAAQP 588
               P P ++    A P   A  AP+       P I  +             +  P++  
Sbjct: 77  PLEVPFPQSSSG-TALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSA 135

Query: 589 PTKFIKIAP-AIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSD 647
           P   + +AP ++Q    S+      +  P   A A   S   + AP   AP+    + + 
Sbjct: 136 PLALVALAPHSVQ---KSSAFPPNLLTSPPSVAVAESGSVITLSAP--IAPSEPKTNLNK 190

Query: 648 LQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLT----GPQQQS 703
           + S   P P   P      S  P  +   TP       +  +PQ +   T     PQ + 
Sbjct: 191 VPSEVVPNPKGTPSPPCIVSTVP--YHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKD 248

Query: 704 HQLVS-LQQLQQPTAAHPPQPGPQGSALGLSTQ 735
             + S L   Q P +     P    +AL LSTQ
Sbjct: 249 TTISSVLISPQNPGSLSLKGPVSPPAALSLSTQ 281


>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 67/174 (38%), Positives = 79/174 (45%), Gaps = 19/174 (10%)

Query: 416 VKGPGKMS----HSSSGPA---SVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLP 468
           ++GPG++      S S PA      Q+   +    P PV V  +VS      PP      
Sbjct: 60  LRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVS------PPLEPAAE 113

Query: 469 SSSGKISSGNSFP----PQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAA--APAPAL 522
           S  G   +    P    P  A +P   P  A A   A A  AA  AA  A A  APAPA 
Sbjct: 114 SLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAP 173

Query: 523 AAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPL 576
           A A APA A  AAPA A A APAPAPA APA  AAP  +A    +  Q+   PL
Sbjct: 174 APAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPL 227



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 56/172 (32%), Positives = 71/172 (41%), Gaps = 28/172 (16%)

Query: 511 AAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQ 570
           A A+   P P LA A APA A  AAP  A  A    APA APA A APA A  AAP+ + 
Sbjct: 132 APASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAP 191

Query: 571 KPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPV 630
            P+     A  P P A P     +   A Q + G   L A  +   + G  A G+     
Sbjct: 192 APAPAPAPAPAPAPDAAPQESAEQ--GANQGQRGQEPL-ADQLHSGISGRPAAGT----- 243

Query: 631 QAPGSGAPAPAGISGSDLQSSGGPL------------PDARPGAVQASSPAP 670
                   A A  +G+ ++   GPL            P+   G V A  P+P
Sbjct: 244 --------AAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSP 287



 Score = 34.7 bits (78), Expect = 0.40
 Identities = 35/145 (24%), Positives = 55/145 (37%), Gaps = 7/145 (4%)

Query: 419 PGKMSHSSSGPASVSQLSSWKTPEQ-----PDPVWVQSSVSGKGEKHPPPRTQLPSSSGK 473
           P  ++   + P +V+ L+    P       P PV   +          P     P ++ +
Sbjct: 151 PAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQ 210

Query: 474 ISSGNSFPPQQAGS-PLKRPF-SAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALA 531
            S+       Q G  PL     S  +   AA  AAA+A  AA      P ++   A    
Sbjct: 211 ESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKR 270

Query: 532 AAAAPALAAAAAPAPAPAAAPAVAA 556
           +A   +     AP P+P+AAP V +
Sbjct: 271 SAPEKSSGDVPAPCPSPSAAPGVGS 295


>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 67/174 (38%), Positives = 79/174 (45%), Gaps = 19/174 (10%)

Query: 416 VKGPGKMS----HSSSGPA---SVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLP 468
           ++GPG++      S S PA      Q+   +    P PV V  +VS      PP      
Sbjct: 60  LRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVS------PPLEPAAE 113

Query: 469 SSSGKISSGNSFP----PQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAA--APAPAL 522
           S  G   +    P    P  A +P   P  A A   A A  AA  AA  A A  APAPA 
Sbjct: 114 SLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAP 173

Query: 523 AAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPL 576
           A A APA A  AAPA A A APAPAPA APA  AAP  +A    +  Q+   PL
Sbjct: 174 APAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPL 227



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 56/172 (32%), Positives = 71/172 (41%), Gaps = 28/172 (16%)

Query: 511 AAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQ 570
           A A+   P P LA A APA A  AAP  A  A    APA APA A APA A  AAP+ + 
Sbjct: 132 APASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAP 191

Query: 571 KPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPV 630
            P+     A  P P A P     +   A Q + G   L A  +   + G  A G+     
Sbjct: 192 APAPAPAPAPAPAPDAAPQESAEQ--GANQGQRGQEPL-ADQLHSGISGRPAAGT----- 243

Query: 631 QAPGSGAPAPAGISGSDLQSSGGPL------------PDARPGAVQASSPAP 670
                   A A  +G+ ++   GPL            P+   G V A  P+P
Sbjct: 244 --------AAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSP 287



 Score = 34.7 bits (78), Expect = 0.40
 Identities = 35/145 (24%), Positives = 55/145 (37%), Gaps = 7/145 (4%)

Query: 419 PGKMSHSSSGPASVSQLSSWKTPEQ-----PDPVWVQSSVSGKGEKHPPPRTQLPSSSGK 473
           P  ++   + P +V+ L+    P       P PV   +          P     P ++ +
Sbjct: 151 PAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQ 210

Query: 474 ISSGNSFPPQQAGS-PLKRPF-SAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALA 531
            S+       Q G  PL     S  +   AA  AAA+A  AA      P ++   A    
Sbjct: 211 ESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKR 270

Query: 532 AAAAPALAAAAAPAPAPAAAPAVAA 556
           +A   +     AP P+P+AAP V +
Sbjct: 271 SAPEKSSGDVPAPCPSPSAAPGVGS 295


>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
           sapiens]
          Length = 316

 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 67/174 (38%), Positives = 79/174 (45%), Gaps = 19/174 (10%)

Query: 416 VKGPGKMS----HSSSGPA---SVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLP 468
           ++GPG++      S S PA      Q+   +    P PV V  +VS      PP      
Sbjct: 71  LRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVS------PPLEPAAE 124

Query: 469 SSSGKISSGNSFP----PQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAA--APAPAL 522
           S  G   +    P    P  A +P   P  A A   A A  AA  AA  A A  APAPA 
Sbjct: 125 SLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAP 184

Query: 523 AAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPL 576
           A A APA A  AAPA A A APAPAPA APA  AAP  +A    +  Q+   PL
Sbjct: 185 APAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPL 238



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 56/172 (32%), Positives = 71/172 (41%), Gaps = 28/172 (16%)

Query: 511 AAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQ 570
           A A+   P P LA A APA A  AAP  A  A    APA APA A APA A  AAP+ + 
Sbjct: 143 APASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAP 202

Query: 571 KPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPV 630
            P+     A  P P A P     +   A Q + G   L A  +   + G  A G+     
Sbjct: 203 APAPAPAPAPAPAPDAAPQESAEQ--GANQGQRGQEPL-ADQLHSGISGRPAAGT----- 254

Query: 631 QAPGSGAPAPAGISGSDLQSSGGPL------------PDARPGAVQASSPAP 670
                   A A  +G+ ++   GPL            P+   G V A  P+P
Sbjct: 255 --------AAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSP 298



 Score = 34.7 bits (78), Expect = 0.40
 Identities = 35/145 (24%), Positives = 55/145 (37%), Gaps = 7/145 (4%)

Query: 419 PGKMSHSSSGPASVSQLSSWKTPEQ-----PDPVWVQSSVSGKGEKHPPPRTQLPSSSGK 473
           P  ++   + P +V+ L+    P       P PV   +          P     P ++ +
Sbjct: 162 PAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQ 221

Query: 474 ISSGNSFPPQQAGS-PLKRPF-SAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALA 531
            S+       Q G  PL     S  +   AA  AAA+A  AA      P ++   A    
Sbjct: 222 ESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKR 281

Query: 532 AAAAPALAAAAAPAPAPAAAPAVAA 556
           +A   +     AP P+P+AAP V +
Sbjct: 282 SAPEKSSGDVPAPCPSPSAAPGVGS 306


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 135/523 (25%), Positives = 177/523 (33%), Gaps = 124/523 (23%)

Query: 425 SSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQ 484
           + +GPA+ ++ +    PE P     ++   G G + P P    PS    +      PP  
Sbjct: 71  AGAGPAAPAEGAPGAAPEPPPAG--RARPGGGGPQRPGP----PSPRRPLVPAGPAPP-- 122

Query: 485 AGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAA--AAAPALAAAAAPALAAAA 542
             + L+ P   +A    + A   AAAA AA   PAPA  A  A   ALAA A P      
Sbjct: 123 -AAKLRPPPEGSAG---SCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGP 178

Query: 543 APAPAP-------------------------AAAPAVA---------------AAP---- 558
            P P P                         AAAPAV+               AAP    
Sbjct: 179 GPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVI 238

Query: 559 ------AAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAIN 612
                  AAA  AP+    P+ P   A    P   PP       P        T   A+ 
Sbjct: 239 QTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAV- 297

Query: 613 VEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGAVQASSPAPLQ 672
              P   A   G S     AP   A  PAG+SG       GP   A   A    + +P +
Sbjct: 298 ---PPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQP-----GPGAAAAAPAPGVKAESPKR 349

Query: 673 FFLNTPEGLRPLTLL-QVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSALG 731
                P   + L         ++++ GP  Q         L  P A  PP P   G+  G
Sbjct: 350 VVQAAPPAAQTLAASGPASTAASMVIGPTMQG-------ALPSPAAVPPPAP---GTPTG 399

Query: 732 LSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQ--------QGVQLPS- 782
           L  +G A    Q L   PT   SG++    P VL    + ++PQ        Q  QLP  
Sbjct: 400 L-PKGAAGAVTQSLSRTPTATTSGIRATLTPTVL----APRLPQPPQNPTNIQNFQLPPG 454

Query: 783 --VLRQQQPQ----PQPPKLQL------QPQWQPKPRQEQPQS---------QQQQPQHI 821
             ++R +  Q    PQ    Q+      QPQ    PR   P S         Q      I
Sbjct: 455 MVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPII 514

Query: 822 QLQTQQLRVLQQPQHIQLQTQQLRVLQ-----QPVFLATGAVQ 859
             Q     +++Q    Q   Q    LQ     QP  +  GA Q
Sbjct: 515 ARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQ 557



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 115/415 (27%), Positives = 155/415 (37%), Gaps = 68/415 (16%)

Query: 395 PGSETDAGRAVSQAQES----VQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQ--PDPVW 448
           PG    AG   +Q        + S       +S  ++GPA++  L     P      P +
Sbjct: 184 PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPF 243

Query: 449 VQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAA 508
           V ++         PP    P++          PP  A + L RP    A    AA A   
Sbjct: 244 VGAAAPPAPAAPSPPAAPAPAAPAAAPP----PPPPAPATLARPPGHPAGPPTAAPAVPP 299

Query: 509 AAAA----AAAAAPAPALAAAAAPALAAAAAPALAAAAAPAP---APAAAPAVAAAPAAA 561
            AAA    +A AAPAPA AA     ++    P  AAAAAPAP   A +    V AAP AA
Sbjct: 300 PAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPG-AAAAAPAPGVKAESPKRVVQAAPPAA 358

Query: 562 ---ASAAPSHSQKPSV--PLIQASRPCPAAQPPTKFIKIAPAIQLRTG-STGLKAINVEG 615
              A++ P+ +    V  P +Q + P PAA PP       PA    TG   G      + 
Sbjct: 359 QTLAASGPASTAASMVIGPTMQGALPSPAAVPP-------PAPGTPTGLPKGAAGAVTQS 411

Query: 616 PVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGAVQASSPAPLQFFL 675
             +   A  S  +    P   AP               P P   P  +Q     P    +
Sbjct: 412 LSRTPTATTSGIRATLTPTVLAPRL-------------PQPPQNPTNIQNFQLPPGMVLV 458

Query: 676 NTPEGLRPLTLLQVPQGSAVLTGPQQQSH---QLVSLQQLQQPTAAHPPQ------PGPQ 726
            +  G     LL +PQ    L   Q Q+H   Q     +   PT+A P Q      PG  
Sbjct: 459 RSENG----QLLMIPQ--QALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTP 512

Query: 727 GSALGLSTQ---GQAFPAQQLLKVNPTRARS-GLQPQPQPAVLSLLGSAQVPQQG 777
             A  ++      Q   AQ  ++ + T  RS G+QPQ     L L G+AQ    G
Sbjct: 513 IIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQ-----LVLGGAAQTASLG 562



 Score = 63.5 bits (153), Expect = 8e-10
 Identities = 92/348 (26%), Positives = 117/348 (33%), Gaps = 70/348 (20%)

Query: 494 SAAAAIAAAAA-----AAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAP 548
           S  + +AA+AA     A       AAAA        + +PA AA A PA  A  AP  AP
Sbjct: 28  SLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAP 87

Query: 549 AAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGL 608
              PA  A P       P     P  PL+ A    PAA       K+ P  +   GS   
Sbjct: 88  EPPPAGRARPGGGGPQRPG-PPSPRRPLVPAGPAPPAA-------KLRPPPEGSAGSC-- 137

Query: 609 KAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSG---------GPLPDAR 659
                  PV  A A+ +  +P  A  +    PA ++       G         GP   A 
Sbjct: 138 ------APVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAG 191

Query: 660 PGAVQ-------------ASSPAPLQFFLNTPEGLRPL-------TLLQVPQGSAVLTGP 699
           PGA Q             A++PA +    N P  L PL       T++Q P        P
Sbjct: 192 PGAAQTLNGSAALLNSHHAAAPA-VSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPP 250

Query: 700 QQQSHQLVSLQQLQQPTAAHPPQP-------GPQGSALGLSTQGQAFPAQQLLKVNPTRA 752
              +    +      P AA PP P        P G   G  T   A P     +      
Sbjct: 251 APAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQ---NGG 307

Query: 753 RSGLQPQPQPAVLSLLG---------SAQVPQQGVQLPSVLRQQQPQP 791
            +G  P P PA     G         +A  P  GV+  S  R  Q  P
Sbjct: 308 SAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAP 355



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 116/525 (22%), Positives = 171/525 (32%), Gaps = 143/525 (27%)

Query: 383 QPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPE 442
           QP P   +A   PG + ++ + V QA          P   + ++SGPAS +         
Sbjct: 328 QPGPGAAAAAPAPGVKAESPKRVVQAAP--------PAAQTLAASGPASTA--------- 370

Query: 443 QPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAA 502
                   S V G            P+  G + S  + PP   G+P   P  AA A+  +
Sbjct: 371 -------ASMVIG------------PTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQS 411

Query: 503 AAAAAAAAAAAAAAAPAPALAAAAAP---------------------------------- 528
            +    A  +   A   P + A   P                                  
Sbjct: 412 LSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQ 471

Query: 529 ALAAAAAPALA---AAAAPAPA-PAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCP 584
           ALA   A A A      AP PA P +AP V  +   A        Q     +I+      
Sbjct: 472 ALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQ 531

Query: 585 AAQPPTKFIKIAPAIQ--------LRTGS--------TGLKAINVEGPVQGAQALGSSFK 628
               P+  ++ +P +Q         +T S        TG     V G    + A   + +
Sbjct: 532 TTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETME 591

Query: 629 PVQAPGSGAPAPAGISGSDLQSSGGP------LPDARPGAVQA------------SSPAP 670
            V+   +       ++ S  QS+         + +   G ++A            SSP P
Sbjct: 592 NVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQP 651

Query: 671 --LQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGS 728
             + F   +   LR LT    P  +A +   QQQ                 PP P  Q +
Sbjct: 652 YLVPFLKRSLPALRQLT----PDSAAFIQQSQQQ-----------------PPPPTSQAT 690

Query: 729 ALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQ--VPQQGVQLPSVLRQ 786
              L+    +   Q+          S L    QP VLSL    Q  V +QG   P V+ Q
Sbjct: 691 T-ALTAVVLSSSVQRTAGKTAATVTSAL----QPPVLSLTQPTQVGVGKQGQPTPLVI-Q 744

Query: 787 QQPQP----QPPKLQLQPQWQPKPRQEQPQSQQQQPQHIQLQTQQ 827
           Q P+P    +PP++ L        RQ   +     PQ IQL   Q
Sbjct: 745 QPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPLQ 789


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 130/493 (26%), Positives = 183/493 (37%), Gaps = 77/493 (15%)

Query: 394 RPGSETDAGR-AVSQAQESVQSKVKGPGKMSHSSSG----PASVSQLSSWKTPEQPDPVW 448
           RP   T+  R +VS A E   ++     +   S+ G    PAS S LSS  TP       
Sbjct: 197 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS-LSSSATPLSSP--- 252

Query: 449 VQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAA 508
            +S  S +G    P     P   G      +  P Q   P K    A   ++++  A  +
Sbjct: 253 ARSGPSARGTPRAPAHPSQPKPKGL----QALRPPQVTPPRKDAAPALGPLSSSPLATPS 308

Query: 509 AAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAAS----A 564
            +   A   P P  AA   PA    + P         P+P+A P++   P+  A+    A
Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA 368

Query: 565 APSHSQKP--------SVPLIQA--SRPCPAAQPPTKFIKIAPAIQLRT--GSTGLKAIN 612
            PS +  P        ++P IQ   S   P+ Q P   + ++ ++Q  T  GS  L+A +
Sbjct: 369 PPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALS-SLQATTSLGSPTLQATH 427

Query: 613 ---VEGPVQGAQALGSSFKPVQAPGSGAPAPAGIS---GSDLQSSGGPL--PDARP---- 660
                 P Q   +L S  +P   P    P  A +S      LQ+S  P   P + P    
Sbjct: 428 SFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH 487

Query: 661 -----GAVQASSP-APLQFF----LNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQ 710
                 ++ + SP APL       L T   L P +L   P   A LT P  ++   ++  
Sbjct: 488 PLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPP---ASLTTPPLENLPSLAPP 544

Query: 711 QLQ-------QPTAAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPA 763
            LQ        P    PP P P           QA P+   L   P    S +   P  A
Sbjct: 545 PLQTASAPLTTPHLETPPCPAP--------CPLQAPPSP--LTTPPPETPSSIATPPPQA 594

Query: 764 VLSLLGSAQVPQQGVQLPSVLRQQQPQPQ-PPKLQLQP-QWQPKPRQEQPQSQQQQPQHI 821
             +L   A  P QG+  P +     P PQ PP L L P Q  P P    P S    P   
Sbjct: 595 PPAL---ASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ 651

Query: 822 QLQTQQLRVLQQP 834
                 + +LQ P
Sbjct: 652 APNALAVHLLQAP 664



 Score = 63.5 bits (153), Expect = 8e-10
 Identities = 123/558 (22%), Positives = 197/558 (35%), Gaps = 67/558 (12%)

Query: 369 PRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSG 428
           P + A   S+    +P          P   T  G   S  + S  ++    G+     S 
Sbjct: 79  PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 138

Query: 429 PASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSP 488
             +V++  + + P++       S+ + +    P P T  P+ + +  +  +    + G P
Sbjct: 139 EETVARGKATEAPKRS----ALSAGARRDTSGPTPGTPSPAMARRSRAAGT----EVGLP 190

Query: 489 LKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAA--AAAPALAAAAAPALAAAAAPAP 546
              P +           + ++A+  +   P+PA     +A   L   A+ +L+++A P  
Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250

Query: 547 APA-AAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGS 605
           +PA + P+    P A     P+H  +P    +QA RP P   PP K    APA+   + S
Sbjct: 251 SPARSGPSARGTPRA-----PAHPSQPKPKGLQALRP-PQVTPPRK--DAAPALGPLSSS 302

Query: 606 -------TGLKAINVEGPVQGAQALGSSFKPVQ--------APGSGA--------PAPAG 642
                  +G KA  V  P   A  L ++  P          AP S +        P+P  
Sbjct: 303 PLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPA 362

Query: 643 ISGSDLQSSGGPLPDARPGAVQASSPAPLQFFLNTPE---GLRPLTLLQVPQGSAVLTGP 699
              S    S    P   P ++Q   P  +   L +P       PL L  +   +++ +  
Sbjct: 363 TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPT 422

Query: 700 QQQSHQLVSLQQLQQPT--------AAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNPTR 751
            Q +H  +++   Q           A+ PP   P  + L L       P Q  L    + 
Sbjct: 423 LQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASP---PLQTSLSPAVSP 479

Query: 752 ARSGLQPQPQPAVLSLLG-SAQVPQQGVQLPSVLRQQQPQPQPPKLQLQPQWQPKPRQEQ 810
             S L   P  A+ SL   S Q P   + +P +  + Q    PP LQ  P     P  E 
Sbjct: 480 LSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL--ETQSSLAPPSLQTPPASLTTPPLEN 537

Query: 811 PQSQQQQP---QHIQLQTQQLRVLQQPQHIQLQTQQLRVLQQPVFLATGAVQIVQPHPGV 867
             S    P       L T  L     P    LQ     +   P    +    I  P P  
Sbjct: 538 LPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS---SIATPPP-- 592

Query: 868 QVGSQLVDQRKEGKPTPP 885
           Q    L     +G P+PP
Sbjct: 593 QAPPALASPPLQGLPSPP 610



 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 89/345 (25%), Positives = 121/345 (35%), Gaps = 40/345 (11%)

Query: 427  SGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAG 486
            S PAS     S   P Q  P      ++    + PP     P  S   +     PP  A 
Sbjct: 709  SPPASPPMSPSATPPPQAPP-----PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAA 763

Query: 487  SPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAP 546
             PL+ P S  A++  +  A     A  A A P P  A  + PA     AP   +A+ P  
Sbjct: 764  PPLQVPPSPPASLPMSPLAKPPPQAPPALATP-PLQALPSPPASFPGQAPFSPSASLPM- 821

Query: 547  APAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGST 606
            +P A P   A P  AA         P+ P +QA R  P   P T        + L  G  
Sbjct: 822  SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 881

Query: 607  GLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGG----PLPDARPGA 662
               + +    + G    G S        S    P  + G D    GG    P PDA   A
Sbjct: 882  PPPSRSPSSTLSGPDLAGHS-------SSATSTPEELRGYDSGPEGGAAASPPPDAELAA 934

Query: 663  VQASS----PAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAA 718
               ++    PAP   F   P           P      TGP   +  L ++ + + P +A
Sbjct: 935  CHPAAWSRGPAPPLAFRGAP---------GAPLPWPPATGP-GSADGLCTIYETEGPESA 984

Query: 719  HPP----QPGPQ-GSALGLSTQGQAFPAQQLLKVNPTRARSGLQP 758
             P      PGP  G++ G +  G    A      +P +AR G  P
Sbjct: 985  TPAPGALDPGPSPGTSGGKAAAGAGAGASSR---SPKQARLGELP 1026



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 92/406 (22%), Positives = 137/406 (33%), Gaps = 42/406 (10%)

Query: 446 PVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAA 505
           P+ V  S++    + PP    L S     S G+             P    A++ + +  
Sbjct: 388 PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP 447

Query: 506 AAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPA---PAPAAAPAVAAAPAAAA 562
           A+    +    AP   L+  A+P L  + +PA++  ++P    P  A +   + +P A  
Sbjct: 448 ASTPPDSPPLQAP---LSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPL 504

Query: 563 SAA---PSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQG 619
           S+    P  +Q    P    + P     PP + +       L+T S  L   ++E P   
Sbjct: 505 SSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCP 564

Query: 620 AQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGAVQASSPAPLQFFLNTPE 679
           A        P+QAP S    P   + S + +     P A         P+P    L TP 
Sbjct: 565 APC------PLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPP 618

Query: 680 GLRPLTL----LQVPQGSAV------LTGPQQQSHQLVSLQQLQQPTAAHPPQP--GPQG 727
              P  L    LQ P           L  P  Q+   +++  LQ P +  P  P   P  
Sbjct: 619 PQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 678

Query: 728 SALGLSTQGQAFPAQQL--------LKVNPTRARS-----GLQPQPQPAVLSLLGSAQVP 774
                     A P  Q         L+V P+   S        P PQ          QVP
Sbjct: 679 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP 738

Query: 775 QQGVQLPSVLRQQQPQPQPPKLQLQPQWQ--PKPRQEQPQSQQQQP 818
                 P +     P P+ P L   P  Q  P P    P S   +P
Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP 784



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 100/419 (23%), Positives = 143/419 (34%), Gaps = 67/419 (15%)

Query: 490 KRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAA----------APALA 539
           K    AAA   AA A          +  P P +  AA   L AA           A  + 
Sbjct: 7   KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66

Query: 540 AAAAPAPAPAAAPAVAAAPAA--AASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAP 597
            A  P  AP A P  +A  ++   AS  P+  +    P  + + P P + P        P
Sbjct: 67  GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126

Query: 598 ------AIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSS 651
                  +++    T  +    E P + A + G+  +    P  G P+PA    S    +
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGAR-RDTSGPTPGTPSPAMARRSRAAGT 185

Query: 652 ----GGPLPDARP------------GAVQASSPAPLQFFLNTPE---GL-----RPLTLL 687
                 P P ARP             A + S+  P       P    GL     R L+  
Sbjct: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245

Query: 688 QVPQGSAVLTGPQQQSHQLVSLQQLQQPTA-AHPPQPGPQG-SALG----LSTQGQAFPA 741
             P  S   +GP  +            P A AHP QP P+G  AL        +  A PA
Sbjct: 246 ATPLSSPARSGPSARG----------TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295

Query: 742 QQLLKVNP--TRARSGLQPQPQPA---VLSLLGSAQVPQQGVQLPSVLRQQQPQPQPPKL 796
              L  +P  T + SG + +P P      + L +   P   +  P  L    P   PP L
Sbjct: 296 LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPS-APPSL 354

Query: 797 QLQPQWQPKPRQEQPQSQQQQPQHIQLQTQQLRVLQQPQHIQLQTQQLRVLQQPVFLAT 855
           Q  P     P  + P S    P       Q +  +Q P    L +  L+    P+ L++
Sbjct: 355 QTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPH--SLTSPSLQAPPSPLALSS 411



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 89/352 (25%), Positives = 123/352 (34%), Gaps = 51/352 (14%)

Query: 427  SGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAG 486
            S PAS     S   P Q  P     S++    + PP     P  S   +     PP  A 
Sbjct: 678  SPPASPPVSPSATPPSQAPP-----SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA 732

Query: 487  SPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAP-- 544
             PL+ P           +  A+   + +A  P       AAP L    +P  +   +P  
Sbjct: 733  PPLQVP----------PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLA 782

Query: 545  APAPAAAPAVAAAPAAAASAAPS-------HSQKPSVPLIQASRPCPAAQPPTKFIKIAP 597
             P P A PA+A  P  A  + P+        S   S+P+   + P P A P    +  AP
Sbjct: 783  KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP----VLAAP 838

Query: 598  AIQLRTGSTGLKAINV--EGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPL 655
             +Q+         +      P  G     S  +   A   G P P   S S   S     
Sbjct: 839  LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG---- 894

Query: 656  PD-ARPGAVQASSPAPLQFFLNTPEG-----LRPLTLLQVPQGSAVLTGPQQQSHQLVSL 709
            PD A   +   S+P  L+ + + PEG       P   L     +A   GP       ++ 
Sbjct: 895  PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPP----LAF 950

Query: 710  QQLQQPTAAHPPQPGPQGSALGL----STQG--QAFPAQQLLKVNPTRARSG 755
            +         PP  GP GSA GL     T+G   A PA   L   P+   SG
Sbjct: 951  RGAPGAPLPWPPATGP-GSADGLCTIYETEGPESATPAPGALDPGPSPGTSG 1001



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 78/304 (25%), Positives = 107/304 (35%), Gaps = 38/304 (12%)

Query: 441 PEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQA--GSPLKRPFSAAAA 498
           P Q  P      + G      PP + L +   +     + PP QA    P   P S  A 
Sbjct: 591 PPQAPPALASPPLQGLPS---PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLAT 647

Query: 499 IAAAAAAAAAAAAAAAAAAP-------APALAAAAAPALAAAAAPALAAAAAPAPAPAAA 551
            +  A  A A     A  +P       AP    A+ P   +A  P+ A  +  AP     
Sbjct: 648 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 707

Query: 552 PAVAAAPAAAASAAPSHSQKP--SVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLK 609
           P+  A+P  + SA P     P  + P +Q   P P A PP     ++P+    T    + 
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVP-PSPPASPP-----MSPS---ATPPPRVP 758

Query: 610 AINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGAVQASSPA 669
            +    P+Q   +  +S            AP  ++   LQ+   P P + PG    S  A
Sbjct: 759 PLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSP-PASFPGQAPFSPSA 817

Query: 670 PLQFF-LNTPEGLRPLTLLQVPQGSAVLTGP-QQQSHQLVSLQQLQQPTAAHPPQPGPQG 727
            L    L TP           PQ   VL  P  Q      +   LQ P    PP PGP  
Sbjct: 818 SLPMSPLATPP----------PQAPPVLAAPLLQVPPSPPASPTLQAP--RRPPTPGPDT 865

Query: 728 SALG 731
           S  G
Sbjct: 866 SVSG 869



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 53/192 (27%), Positives = 71/192 (36%), Gaps = 41/192 (21%)

Query: 429  PASVSQLSSWKTPEQPDPVWVQSSVSGK------GEKHPPPRTQLPSSS-------GKIS 475
            P S     + + P +P      +SVSG           PPP ++ PSS+       G  S
Sbjct: 843  PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 902

Query: 476  SGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAA 535
            S  S P +  G     P   AAA     A  AA   AA +  PAP LA   AP       
Sbjct: 903  SATSTPEELRGYD-SGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 961

Query: 536  PALAAAAA-------------------------PAPAPAAAPAVAAAPAAAASAAPSHSQ 570
            PA    +A                         P+P  +   A A A A A+S +P  ++
Sbjct: 962  PATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQAR 1021

Query: 571  KPSVPL--IQAS 580
               +PL  +QAS
Sbjct: 1022 LGELPLGALQAS 1033


>gi|239745807 PREDICTED: keratin associated protein 4-9 [Homo
           sapiens]
          Length = 254

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 60/196 (30%), Positives = 85/196 (43%), Gaps = 18/196 (9%)

Query: 408 AQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQL 467
           A+ SV+     P  +   ++GP + +    +     P      +S+       P P    
Sbjct: 10  AKTSVRRPAAAPAAVRPPAAGPPAAAPAVVYPAAAGPSA----ASLCAANPLVPAPAAVR 65

Query: 468 PSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAA 527
           P  +G  ++  +     A  P      AA  +A A AA    AA   AA+PA    AA  
Sbjct: 66  PPVAGPPATAPAVVCPAAAGPSAASLRAANPLAVAPAAVRRPAATLGAASPAAVAPAAVC 125

Query: 528 PALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAA--ASAAP------SHSQKPSVPLIQA 579
           PA A+ +A +L AA+  A APAAA   AAAP A   A+AAP      S ++ P+ PL  A
Sbjct: 126 PAAASPSAASLCAASPTAAAPAAASPAAAAPLAVNPAAAAPAAACVQSVAESPATPLAIA 185

Query: 580 ------SRPCPAAQPP 589
                 + P P A PP
Sbjct: 186 QPVSSPAAPAPCAVPP 201



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 81/262 (30%), Positives = 107/262 (40%), Gaps = 40/262 (15%)

Query: 485 AGSPLKRPFSAAAAI---AAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAA 541
           A + ++RP +A AA+   AA   AAA A    AAA P+ A   AA P + A AA     A
Sbjct: 10  AKTSVRRPAAAPAAVRPPAAGPPAAAPAVVYPAAAGPSAASLCAANPLVPAPAAVRPPVA 69

Query: 542 AAPAPAPAAAPAVAAAPAAAA-------SAAPSHSQKPSVPLIQASRPCPAAQPPTKFIK 594
             PA APA     AA P+AA+       + AP+  ++P+  L  AS   PAA  P     
Sbjct: 70  GPPATAPAVVCPAAAGPSAASLRAANPLAVAPAAVRRPAATLGAAS---PAAVAPA---A 123

Query: 595 IAPAIQLRTGSTGLKAINVEGPVQGAQALGS--SFKPVQA-PGSGAPAPAGISGSDLQSS 651
           + PA      S    ++    P   A A  S  +  P+   P + APA A +  S  +S 
Sbjct: 124 VCPA----AASPSAASLCAASPTAAAPAAASPAAAAPLAVNPAAAAPAAACVQ-SVAESP 178

Query: 652 GGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVP--------QGSAVLTGPQQQS 703
             PL  A+P     SSPA        P    P  L  +P          S VLT   Q+ 
Sbjct: 179 ATPLAIAQP----VSSPAAPAPCAVPPLAAEPTALAYLPLHHWPTDVDPSTVLTIRIQE- 233

Query: 704 HQLVSLQQLQQPTAAHPPQPGP 725
              V L    +     P  P P
Sbjct: 234 ---VGLMSFNRMELMFPMSPSP 252



 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 55/178 (30%), Positives = 74/178 (41%), Gaps = 29/178 (16%)

Query: 495 AAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAA-PA 553
           AAA  +    AAA AA    AA P  A  A   PA A  +A +L AA    PAPAA  P 
Sbjct: 8   AAAKTSVRRPAAAPAAVRPPAAGPPAAAPAVVYPAAAGPSAASLCAANPLVPAPAAVRPP 67

Query: 554 VAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINV 613
           VA  PA A +     +  PS   ++A+ P          + +APA   R  +T       
Sbjct: 68  VAGPPATAPAVVCPAAAGPSAASLRAANP----------LAVAPAAVRRPAAT------- 110

Query: 614 EGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGAVQASSPAPL 671
                    LG++     AP +  PA A  S + L ++      A P A   ++ APL
Sbjct: 111 ---------LGAASPAAVAPAAVCPAAASPSAASLCAASPTA--AAPAAASPAAAAPL 157



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 55/187 (29%), Positives = 75/187 (40%), Gaps = 18/187 (9%)

Query: 462 PPRTQLPSSSGKI----SSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAA 517
           PP    P+++  +    ++G S     A +PL    +A     A   A A A    AAA 
Sbjct: 26  PPAAGPPAAAPAVVYPAAAGPSAASLCAANPLVPAPAAVRPPVAGPPATAPAVVCPAAAG 85

Query: 518 PAPALAAAAAPALAAAAAPALAAAAAPAPAPAA-APAVAAAPAAAASAAPSHSQKPSVPL 576
           P+ A   AA P   A AA    AA   A +PAA APA     AA+ SAA   +  P+   
Sbjct: 86  PSAASLRAANPLAVAPAAVRRPAATLGAASPAAVAPAAVCPAAASPSAASLCAASPTAAA 145

Query: 577 IQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSG 636
             A+ P  AA         APA           A  V+   +      +  +PV +P   
Sbjct: 146 PAAASPAAAAPLAVNPAAAAPA-----------AACVQSVAESPATPLAIAQPVSSP--A 192

Query: 637 APAPAGI 643
           APAP  +
Sbjct: 193 APAPCAV 199


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 70.9 bits (172), Expect = 5e-12
 Identities = 111/477 (23%), Positives = 160/477 (33%), Gaps = 63/477 (13%)

Query: 365 GKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSH 424
           G +   +  R+K   SP       +      G  + +  + S      ++  K   K+  
Sbjct: 25  GSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKE 84

Query: 425 SSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQ 484
            +S P   ++    K     +     SS   K ++   P +    S G+  S +S     
Sbjct: 85  EASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSP---SEGEGESSDSRSVND 141

Query: 485 AGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAP 544
            GS   +         + +  +     + + ++    +  A  PAL A      A ++AP
Sbjct: 142 EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 201

Query: 545 A-----PAPAAAPAVAAAP---AAAASAAPSHSQKPSVPLIQAS-RPCPAAQP------- 588
                 P P   P+  A P   +  AS AP+  Q P+ P+     +  PA  P       
Sbjct: 202 PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 261

Query: 589 PTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGI-SGSD 647
           P       P +Q  TGS G             Q    S       G G P P  + +G  
Sbjct: 262 PPPHPSPHPPLQPLTGSAG-------------QPSAPSHAQPPLHGQGPPGPHSLQAGPL 308

Query: 648 LQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLV 707
           LQ  G P P   P    +   APL     +P    P T LQ+P   + L   Q    Q +
Sbjct: 309 LQHPGPPQPFGLPPQA-SQGQAPLG---TSPAAAYPHTSLQLPASQSALQSQQPPREQPL 364

Query: 708 SLQQLQQPTAAHPPQ-PGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLS 766
               L  P    PP  P PQ             PA Q  K  P  +         P+  S
Sbjct: 365 PPAPLAMPHIKPPPTTPIPQ------------LPAPQAHKHPPHLSG--------PSPFS 404

Query: 767 LLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQLQPQWQPKPRQ-EQP----QSQQQQP 818
           +  +   P     L S+     P   PP LQL PQ QP P    QP    QSQ   P
Sbjct: 405 MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP 461



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 116/459 (25%), Positives = 161/459 (35%), Gaps = 84/459 (18%)

Query: 371 KKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQ------SKVKGPGKMSH 424
           KK+ +K ++    P   +     +  S+T+     S  +   Q      S  +G G+ S 
Sbjct: 76  KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSD 135

Query: 425 S-------SSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKH----PPPRTQLPSSSGK 473
           S       SS P  + Q +   +P  P P   +S      ++      PP  Q P+  G 
Sbjct: 136 SRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT--GV 193

Query: 474 ISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAA--AAAAAAPAPALAAAAAPALA 531
             + +S PP     P   P  +A A+    +  A+ A     A  AP P      APAL 
Sbjct: 194 TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH 253

Query: 532 AAAAPALAAAAAPAPAPAAAPAVAAA--PAAAASAAPS-HSQKPSVP-LIQASRPCPAAQ 587
               P+      P+P P   P   +A  P+A + A P  H Q P  P  +QA        
Sbjct: 254 PQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG 313

Query: 588 PPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGS- 646
           PP  F              GL       P Q +Q         QAP   +PA A    S 
Sbjct: 314 PPQPF--------------GL-------PPQASQG--------QAPLGTSPAAAYPHTSL 344

Query: 647 DLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQG---SAVLTGPQQQS 703
            L +S   L   +P   Q   PAPL      P    P+  L  PQ       L+GP   S
Sbjct: 345 QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFS 404

Query: 704 HQL-----VSLQQLQQPTAAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQP 758
                    +L+ L   +  HPP   P    L L  Q Q  P+        T++++ L P
Sbjct: 405 MNANLPPPPALKPLSSLSTHHPPSAHP--PPLQLMPQSQPLPSSPAQPPGLTQSQN-LPP 461

Query: 759 QPQPAVLSLLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQ 797
            P          A  P  G+         Q  PQPP  Q
Sbjct: 462 PP----------ASHPPTGL--------HQVAPQPPFAQ 482



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 66/248 (26%), Positives = 90/248 (36%), Gaps = 36/248 (14%)

Query: 429 PASVSQLSSWKTP-EQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGS 487
           PAS S L S + P EQP P    +    K    PPP T +P         +  PP  +G 
Sbjct: 347 PASQSALQSQQPPREQPLPPAPLAMPHIK----PPPTTPIPQLPAP--QAHKHPPHLSGP 400

Query: 488 PLKRPFSAAAAIAAAAAAAAAAAAAA---AAAAPAPALAAAAAPALAAAAA--PALAAAA 542
               PFS  A +    A    ++ +     +A P P      +  L ++ A  P L  + 
Sbjct: 401 S---PFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQ 457

Query: 543 APAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLR 602
              P PA+ P       A     P  +Q P VP      P P   PPT      P+    
Sbjct: 458 NLPPPPASHPPTGLHQVA---PQPPFAQHPFVP----GGP-PPITPPT-----CPSTSTP 504

Query: 603 TGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGA 662
               G  A   + P  GA A G S     A GS  P P  +   +        P++ P  
Sbjct: 505 PAGPGTSA---QPPCSGAAASGGSI----AGGSSCPLPT-VQIKEEALDDAEEPESPPPP 556

Query: 663 VQASSPAP 670
            ++ SP P
Sbjct: 557 PRSPSPEP 564


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 70.9 bits (172), Expect = 5e-12
 Identities = 111/477 (23%), Positives = 160/477 (33%), Gaps = 63/477 (13%)

Query: 365  GKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSH 424
            G +   +  R+K   SP       +      G  + +  + S      ++  K   K+  
Sbjct: 579  GSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKE 638

Query: 425  SSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQ 484
             +S P   ++    K     +     SS   K ++   P +    S G+  S +S     
Sbjct: 639  EASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSP---SEGEGESSDSRSVND 695

Query: 485  AGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAP 544
             GS   +         + +  +     + + ++    +  A  PAL A      A ++AP
Sbjct: 696  EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 755

Query: 545  A-----PAPAAAPAVAAAP---AAAASAAPSHSQKPSVPLIQAS-RPCPAAQP------- 588
                  P P   P+  A P   +  AS AP+  Q P+ P+     +  PA  P       
Sbjct: 756  PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 815

Query: 589  PTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGI-SGSD 647
            P       P +Q  TGS G             Q    S       G G P P  + +G  
Sbjct: 816  PPPHPSPHPPLQPLTGSAG-------------QPSAPSHAQPPLHGQGPPGPHSLQAGPL 862

Query: 648  LQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLV 707
            LQ  G P P   P    +   APL     +P    P T LQ+P   + L   Q    Q +
Sbjct: 863  LQHPGPPQPFGLPPQA-SQGQAPLG---TSPAAAYPHTSLQLPASQSALQSQQPPREQPL 918

Query: 708  SLQQLQQPTAAHPPQ-PGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLS 766
                L  P    PP  P PQ             PA Q  K  P  +         P+  S
Sbjct: 919  PPAPLAMPHIKPPPTTPIPQ------------LPAPQAHKHPPHLSG--------PSPFS 958

Query: 767  LLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQLQPQWQPKPRQ-EQP----QSQQQQP 818
            +  +   P     L S+     P   PP LQL PQ QP P    QP    QSQ   P
Sbjct: 959  MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP 1015



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 116/459 (25%), Positives = 161/459 (35%), Gaps = 84/459 (18%)

Query: 371  KKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQ------SKVKGPGKMSH 424
            KK+ +K ++    P   +     +  S+T+     S  +   Q      S  +G G+ S 
Sbjct: 630  KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSD 689

Query: 425  S-------SSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKH----PPPRTQLPSSSGK 473
            S       SS P  + Q +   +P  P P   +S      ++      PP  Q P+  G 
Sbjct: 690  SRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT--GV 747

Query: 474  ISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAA--AAAAAAPAPALAAAAAPALA 531
              + +S PP     P   P  +A A+    +  A+ A     A  AP P      APAL 
Sbjct: 748  TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH 807

Query: 532  AAAAPALAAAAAPAPAPAAAPAVAAA--PAAAASAAPS-HSQKPSVP-LIQASRPCPAAQ 587
                P+      P+P P   P   +A  P+A + A P  H Q P  P  +QA        
Sbjct: 808  PQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG 867

Query: 588  PPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGS- 646
            PP  F              GL       P Q +Q         QAP   +PA A    S 
Sbjct: 868  PPQPF--------------GL-------PPQASQG--------QAPLGTSPAAAYPHTSL 898

Query: 647  DLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQG---SAVLTGPQQQS 703
             L +S   L   +P   Q   PAPL      P    P+  L  PQ       L+GP   S
Sbjct: 899  QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFS 958

Query: 704  HQL-----VSLQQLQQPTAAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQP 758
                     +L+ L   +  HPP   P    L L  Q Q  P+        T++++ L P
Sbjct: 959  MNANLPPPPALKPLSSLSTHHPPSAHP--PPLQLMPQSQPLPSSPAQPPGLTQSQN-LPP 1015

Query: 759  QPQPAVLSLLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQ 797
             P          A  P  G+         Q  PQPP  Q
Sbjct: 1016 PP----------ASHPPTGL--------HQVAPQPPFAQ 1036



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 66/248 (26%), Positives = 90/248 (36%), Gaps = 36/248 (14%)

Query: 429  PASVSQLSSWKTP-EQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGS 487
            PAS S L S + P EQP P    +    K    PPP T +P         +  PP  +G 
Sbjct: 901  PASQSALQSQQPPREQPLPPAPLAMPHIK----PPPTTPIPQLPAP--QAHKHPPHLSGP 954

Query: 488  PLKRPFSAAAAIAAAAAAAAAAAAAA---AAAAPAPALAAAAAPALAAAAA--PALAAAA 542
                PFS  A +    A    ++ +     +A P P      +  L ++ A  P L  + 
Sbjct: 955  S---PFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQ 1011

Query: 543  APAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLR 602
               P PA+ P       A     P  +Q P VP      P P   PPT      P+    
Sbjct: 1012 NLPPPPASHPPTGLHQVA---PQPPFAQHPFVP----GGP-PPITPPT-----CPSTSTP 1058

Query: 603  TGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGA 662
                G  A   + P  GA A G S     A GS  P P  +   +        P++ P  
Sbjct: 1059 PAGPGTSA---QPPCSGAAASGGSI----AGGSSCPLPT-VQIKEEALDDAEEPESPPPP 1110

Query: 663  VQASSPAP 670
             ++ SP P
Sbjct: 1111 PRSPSPEP 1118


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 70.9 bits (172), Expect = 5e-12
 Identities = 111/477 (23%), Positives = 160/477 (33%), Gaps = 63/477 (13%)

Query: 365  GKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSH 424
            G +   +  R+K   SP       +      G  + +  + S      ++  K   K+  
Sbjct: 579  GSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKE 638

Query: 425  SSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQ 484
             +S P   ++    K     +     SS   K ++   P +    S G+  S +S     
Sbjct: 639  EASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSP---SEGEGESSDSRSVND 695

Query: 485  AGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAP 544
             GS   +         + +  +     + + ++    +  A  PAL A      A ++AP
Sbjct: 696  EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 755

Query: 545  A-----PAPAAAPAVAAAP---AAAASAAPSHSQKPSVPLIQAS-RPCPAAQP------- 588
                  P P   P+  A P   +  AS AP+  Q P+ P+     +  PA  P       
Sbjct: 756  PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 815

Query: 589  PTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGI-SGSD 647
            P       P +Q  TGS G             Q    S       G G P P  + +G  
Sbjct: 816  PPPHPSPHPPLQPLTGSAG-------------QPSAPSHAQPPLHGQGPPGPHSLQAGPL 862

Query: 648  LQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLV 707
            LQ  G P P   P    +   APL     +P    P T LQ+P   + L   Q    Q +
Sbjct: 863  LQHPGPPQPFGLPPQA-SQGQAPLG---TSPAAAYPHTSLQLPASQSALQSQQPPREQPL 918

Query: 708  SLQQLQQPTAAHPPQ-PGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLS 766
                L  P    PP  P PQ             PA Q  K  P  +         P+  S
Sbjct: 919  PPAPLAMPHIKPPPTTPIPQ------------LPAPQAHKHPPHLSG--------PSPFS 958

Query: 767  LLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQLQPQWQPKPRQ-EQP----QSQQQQP 818
            +  +   P     L S+     P   PP LQL PQ QP P    QP    QSQ   P
Sbjct: 959  MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP 1015



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 116/459 (25%), Positives = 161/459 (35%), Gaps = 84/459 (18%)

Query: 371  KKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQ------SKVKGPGKMSH 424
            KK+ +K ++    P   +     +  S+T+     S  +   Q      S  +G G+ S 
Sbjct: 630  KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSD 689

Query: 425  S-------SSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKH----PPPRTQLPSSSGK 473
            S       SS P  + Q +   +P  P P   +S      ++      PP  Q P+  G 
Sbjct: 690  SRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT--GV 747

Query: 474  ISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAA--AAAAAAPAPALAAAAAPALA 531
              + +S PP     P   P  +A A+    +  A+ A     A  AP P      APAL 
Sbjct: 748  TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH 807

Query: 532  AAAAPALAAAAAPAPAPAAAPAVAAA--PAAAASAAPS-HSQKPSVP-LIQASRPCPAAQ 587
                P+      P+P P   P   +A  P+A + A P  H Q P  P  +QA        
Sbjct: 808  PQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG 867

Query: 588  PPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGS- 646
            PP  F              GL       P Q +Q         QAP   +PA A    S 
Sbjct: 868  PPQPF--------------GL-------PPQASQG--------QAPLGTSPAAAYPHTSL 898

Query: 647  DLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQG---SAVLTGPQQQS 703
             L +S   L   +P   Q   PAPL      P    P+  L  PQ       L+GP   S
Sbjct: 899  QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFS 958

Query: 704  HQL-----VSLQQLQQPTAAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQP 758
                     +L+ L   +  HPP   P    L L  Q Q  P+        T++++ L P
Sbjct: 959  MNANLPPPPALKPLSSLSTHHPPSAHP--PPLQLMPQSQPLPSSPAQPPGLTQSQN-LPP 1015

Query: 759  QPQPAVLSLLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQ 797
             P          A  P  G+         Q  PQPP  Q
Sbjct: 1016 PP----------ASHPPTGL--------HQVAPQPPFAQ 1036



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 66/248 (26%), Positives = 90/248 (36%), Gaps = 36/248 (14%)

Query: 429  PASVSQLSSWKTP-EQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGS 487
            PAS S L S + P EQP P    +    K    PPP T +P         +  PP  +G 
Sbjct: 901  PASQSALQSQQPPREQPLPPAPLAMPHIK----PPPTTPIPQLPAP--QAHKHPPHLSGP 954

Query: 488  PLKRPFSAAAAIAAAAAAAAAAAAAA---AAAAPAPALAAAAAPALAAAAA--PALAAAA 542
                PFS  A +    A    ++ +     +A P P      +  L ++ A  P L  + 
Sbjct: 955  S---PFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQ 1011

Query: 543  APAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLR 602
               P PA+ P       A     P  +Q P VP      P P   PPT      P+    
Sbjct: 1012 NLPPPPASHPPTGLHQVA---PQPPFAQHPFVP----GGP-PPITPPT-----CPSTSTP 1058

Query: 603  TGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGA 662
                G  A   + P  GA A G S     A GS  P P  +   +        P++ P  
Sbjct: 1059 PAGPGTSA---QPPCSGAAASGGSI----AGGSSCPLPT-VQIKEEALDDAEEPESPPPP 1110

Query: 663  VQASSPAP 670
             ++ SP P
Sbjct: 1111 PRSPSPEP 1118


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 70.9 bits (172), Expect = 5e-12
 Identities = 58/171 (33%), Positives = 71/171 (41%), Gaps = 15/171 (8%)

Query: 461 PPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAP 520
           PP   + P  +   ++  + PP  A  P   P +AAA    A A  AAAAAA A  +P P
Sbjct: 108 PPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAP---ARAPRAAAAAATAPPSPGP 164

Query: 521 ALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAP-SHSQKPSVPLIQA 579
           A     A   A  AAP  A AA PA AP A P  A  PA AA   P     +P  P  Q 
Sbjct: 165 AQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQ 224

Query: 580 SRPCPAAQPP-----------TKFIKIAPAIQLRTGSTGLKAINVEGPVQG 619
             P P  QPP            + + +   ++   GS G       G VQG
Sbjct: 225 QPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQG 275



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 60/170 (35%), Positives = 70/170 (41%), Gaps = 24/170 (14%)

Query: 505 AAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASA 564
           AA        A  PAP  A   APA AAAAAP    A  P PAP AA A A AP AAA+A
Sbjct: 96  AARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAA 155

Query: 565 APS-HSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQAL 623
           A +  S  P+ P  +A R  P A PP      APA                GP +     
Sbjct: 156 ATAPPSPGPAQPGPRAQRAAPLAAPPP-----APAAPPAVAPPA-------GPRRAPPPA 203

Query: 624 GSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARP----GAVQASSPA 669
            ++ +P   P    PAP        Q    P P  +P    GAV+A   A
Sbjct: 204 VAAREPPLPPPPQPPAPP-------QQQQPPPPQPQPPPEGGAVRAGGAA 246



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 72/283 (25%), Positives = 101/283 (35%), Gaps = 63/283 (22%)

Query: 541 AAAPA-PAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAI 599
           A  PA P P  A A   A AA++SAA  H Q+  +  I + R    A+P  +  +I   +
Sbjct: 2   AGPPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLR-SRKARPDLE--RICRMV 58

Query: 600 QLRTGSTGLKA-INVEGPVQGAQALGSSFK---------PVQAPGSGAPAPAGISGSDLQ 649
           + R G    +    +E  +Q    L  S+K          VQ P  GA  PA        
Sbjct: 59  RRRHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRA---- 114

Query: 650 SSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSL 709
                 P   P A  A++P P       P  +      + P+ +A               
Sbjct: 115 ------PRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAA-------------- 154

Query: 710 QQLQQPTAAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLG 769
                  A  PP PGP            A P  +  +  P  A     P P PA    + 
Sbjct: 155 ------AATAPPSPGP------------AQPGPRAQRAAPLAA-----PPPAPAAPPAVA 191

Query: 770 SAQVPQQGVQLPSVLRQQQPQPQPPKLQLQP-QWQPKPRQEQP 811
               P++    P+V  ++ P P PP+    P Q QP P Q QP
Sbjct: 192 PPAGPRRAPP-PAVAAREPPLPPPPQPPAPPQQQQPPPPQPQP 233


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 70.5 bits (171), Expect = 7e-12
 Identities = 112/422 (26%), Positives = 156/422 (36%), Gaps = 55/422 (13%)

Query: 418  GPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSG 477
            GP  ++ S + P++ +      T     P    S   G      P  + +P  +  ++  
Sbjct: 1489 GPPSLAPSGASPSASALTLGLATA----PSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPA 1544

Query: 478  NSFPPQQAGSPLKRPFSAAA--AIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAA 535
             S P     S L  PF +A   A A A+  A A++A+ A A P   +AA     LA + A
Sbjct: 1545 CS-PVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPA 1603

Query: 536  PALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKI 595
            P LA     AP+P AAP +A++       APS +  P   L  AS P PA  P      +
Sbjct: 1604 PPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSST--PGTSLASAS-PVPAPTP-----VL 1655

Query: 596  APAIQLRTGSTGLKAINVEGPVQG-AQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGP 654
            AP+    +  T L A  V  P+   A     +  P  AP  G  +P+        +  GP
Sbjct: 1656 APS----STQTMLPA-PVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGP 1710

Query: 655  LPDARPGAVQASS--PAPLQFFLNTP-EGLRPLTLLQV----------PQGSA----VLT 697
             P        ASS  P P Q     P   L P   L +          P G A    +  
Sbjct: 1711 FPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTL 1770

Query: 698  GPQQQSHQLVSLQQLQQPTAAHPPQP--GPQGS-ALGLSTQGQAFPAQQLLKVNPTRARS 754
             P   S  L++   +Q  T +  P P  GP  +  L L+      PA Q   +    + S
Sbjct: 1771 APASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSL--VVSAS 1828

Query: 755  GLQPQPQPAVLSLLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQL-----QPQWQPKPRQE 809
            G  P P   V  L  S          P  L  +   P PP         +P+ QP P   
Sbjct: 1829 GAAPLPVTMVSRLPVSKDE-------PDTLTLRSGPPSPPSTATSFGGPRPRRQPPPPPR 1881

Query: 810  QP 811
             P
Sbjct: 1882 SP 1883



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 107/439 (24%), Positives = 150/439 (34%), Gaps = 58/439 (13%)

Query: 393  LRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSS 452
            L PG         ++A     + V+   K+ HS S   S S   +        P+ V SS
Sbjct: 1348 LTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTIS-SPLHVPSS 1406

Query: 453  VSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAA 512
            + G      P    +P+SS   S           S +  P S++  I+      A A+A 
Sbjct: 1407 LPGPASSPMP----IPNSSPLASP--------VSSTVSVPLSSSLPISVPTTLPAPASAP 1454

Query: 513  AAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAA-----SAAP- 566
                  AP   +A+ PAL  +  P LA     AP P +     A+P+A+A     + AP 
Sbjct: 1455 LTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPS 1514

Query: 567  -SHSQKPSVPLIQA----------SRPCPAAQPP-TKFIKIAPAIQLRTGSTGLKAINVE 614
             S SQ P  PL+ A          S   PA  P       +A            +A  + 
Sbjct: 1515 LSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLA 1574

Query: 615  GPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGAVQASSPAPLQFF 674
                 +QAL +   P+ AP +   AP+            P P A P    + +P P+   
Sbjct: 1575 PASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAP 1634

Query: 675  LNTPEGLRPLTLLQVPQGSAVLTGPQQQS----------HQLVSLQQLQQPTAAHPPQPG 724
             +TP G    +   VP  + VL     Q+              S Q L    A  P   G
Sbjct: 1635 SSTP-GTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGG 1693

Query: 725  PQGS---ALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQLP 781
               S   +LG       FP  Q L + P    S L P P   +    G    P Q + L 
Sbjct: 1694 SSPSQTLSLGTGNPQGPFPT-QTLSLTPA---SSLVPTPAQTLSLAPGPPLGPTQTLSL- 1748

Query: 782  SVLRQQQPQPQPPKLQLQP 800
                     P PP     P
Sbjct: 1749 --------APAPPLAPASP 1759



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 80/378 (21%), Positives = 129/378 (34%), Gaps = 57/378 (15%)

Query: 439  KTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPP-----QQAGSPLKRPF 493
            + P  P PV          +  P P  Q+  +S  +S+  + PP     +  G  L  P 
Sbjct: 1016 RAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPL 1075

Query: 494  SAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPA 553
               +        +     +  +  P P L+    P      +PA    ++    P   P 
Sbjct: 1076 QPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPP 1135

Query: 554  VAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINV 613
                P AAA+   + +   +   + A  P P      + + ++P +Q R  S  + +I  
Sbjct: 1136 GYTFPPAAATTTSTTTATATTTAVPAPTPAP------QRLILSPDMQARLPSGEVVSI-- 1187

Query: 614  EGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGAVQASSPAPLQF 673
                   Q    + +PV   G   P    I G+ L  +G     A+   +    P PLQ 
Sbjct: 1188 ------GQLASLAQRPVANAGGSKPLTFQIQGNKLTLTG-----AQVRQLAVGQPRPLQ- 1235

Query: 674  FLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSALGLS 733
                    R +  L       V  G Q   H L+S         A  P PGP   ++  S
Sbjct: 1236 --------RNVVHL-------VSAGGQ---HHLISQPAHVALIQAVAPTPGPTPVSVLPS 1277

Query: 734  TQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSA-----QVPQQGVQLPSVLRQQQ 788
            +     PA   L + P  A      Q  P +++  G       Q P+ G+   + +    
Sbjct: 1278 STPSTTPAPTGLSL-PLAAN-----QVPPTMVNNTGVVKIVVRQAPRDGL---TPVPPLA 1328

Query: 789  PQPQPPKLQLQPQWQPKP 806
            P P+PP   L     P+P
Sbjct: 1329 PAPRPPSSGLPAVLNPRP 1346



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 95/428 (22%), Positives = 140/428 (32%), Gaps = 83/428 (19%)

Query: 401  AGRAVSQAQESV----QSKVKGPGKMSHSSSGPASVSQLSSWKT--PEQPDPVWVQSSVS 454
            A + + QA+E V    Q + +GPG    SS G    +   S K   PE+P     +    
Sbjct: 2342 ARKDLDQAKEEVFRLPQEEEEGPGAGDESSCGTGGGTHRRSKKAKAPERPGTRVSERLRG 2401

Query: 455  GKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAA 514
             + E      T  P  S   +   + PP+                           + A 
Sbjct: 2402 ARAETQGANHT--PVISAHQTRSTTTPPR--------------------------CSPAR 2433

Query: 515  AAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAP-AVAAAPAAAASAAPSHSQKPS 573
               P PA      PA A AA PAL      AP P +AP  +   P     + P  SQ P 
Sbjct: 2434 ERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPP 2493

Query: 574  VPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAP 633
                 A  P PA  PP           L T S+ L              LG    P+ A 
Sbjct: 2494 CS-SPACTPPPACTPPPAHTPPPAQTCLVTPSSPL-------------LLGPPSVPISAS 2539

Query: 634  GSGAPAPAGISGSDLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGS 693
             +  P              G  P+A   A QA         L +PE L   ++      S
Sbjct: 2540 VTNLPL-------------GLRPEAELCA-QA---------LASPESLELASVASSETSS 2576

Query: 694  AVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNPTRAR 753
              L  P+      V +  + +   +  P      SA  L+ +  + P  Q  +   +   
Sbjct: 2577 LSLVPPKDLLPVAVEILPVSEKNLSLTP------SAPSLTLEAGSIPNGQEQEAPDSAEG 2630

Query: 754  SGLQPQPQPAVLSLLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQLQPQWQPKPRQEQPQS 813
            + L   P+   L L  S      G++LP      +P  +P  L+     +     + P S
Sbjct: 2631 TTLTVLPEGEELPLCVS---ESNGLELPPSAASDEPLQEP--LEADRTSEELTEAKTPTS 2685

Query: 814  QQQQPQHI 821
              ++PQ +
Sbjct: 2686 SPEKPQEL 2693



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 86/353 (24%), Positives = 119/353 (33%), Gaps = 65/353 (18%)

Query: 566  PSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGS 625
            P H     V L  A+ P P  +P    +K+   +Q      G   + V  P      LG 
Sbjct: 965  PRHRLSRRVLLEVATAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNP---RAPLGP 1021

Query: 626  SFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGA--VQASSPAPLQFFLNTPEGLRP 683
               PV+ P    P P        Q + GP+P   P +  V AS   P     + P G   
Sbjct: 1022 V--PVRPP----PGPE----LSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVL 1071

Query: 684  LTLLQVPQGS---------AVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSALGLST 734
            L  LQ   GS          VL+G  +     +SL+          P P P  S+L    
Sbjct: 1072 LPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPL 1131

Query: 735  Q---GQAFPAQQLLKVNPTRARSGLQ------PQPQPAVLSLLGSAQVPQQGV----QLP 781
                G  FP       + T A +         P PQ  +LS    A++P   V    QL 
Sbjct: 1132 TVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLA 1191

Query: 782  SVLRQ-------QQP---QPQPPKLQLQPQWQPKPRQEQPQSQQQQPQHIQLQTQQLRVL 831
            S+ ++        +P   Q Q  KL L      +    QP+  Q+   H+     Q  ++
Sbjct: 1192 SLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLI 1251

Query: 832  QQPQHIQLQTQQLRVLQQPVFLATGAVQIVQPHPGVQVGSQLVDQRKEGKPTP 884
             QP H+ L                  +Q V P PG    S L        P P
Sbjct: 1252 SQPAHVAL------------------IQAVAPTPGPTPVSVLPSSTPSTTPAP 1286



 Score = 31.2 bits (69), Expect = 4.5
 Identities = 68/360 (18%), Positives = 120/360 (33%), Gaps = 60/360 (16%)

Query: 146 VRDYRQSSNMQPPGYQSRHILLRPTMQTLAHDVKMMTRDGQKWSQEDKL-QLESQLILAT 204
           +R + +    +    +     LR    T+A DV+      Q WS  +K+ Q + Q  L  
Sbjct: 170 IRHHEEQRQKEERARREEQAKLRRIASTMAKDVR------QFWSNVEKVVQFKQQSRLEE 223

Query: 205 AEPLCLDPSVAVACTANRLLYNKQKMNTDPMKRCLQRYSWPSVKPQQEQSDC-------- 256
                LD  +         +  + +  +D + + L +   P    +   S C        
Sbjct: 224 KRKKALDLHLD-------FIVGQTEKYSDLLSQSLNQ---PLTSSKAGSSPCLGSSSAAS 273

Query: 257 -PPPPELRVSTSG------QKEERKVGQPCELNIAKAGSCVDTWKGRPCDLAVPSEVDVE 309
            PPPP  R+          + EE    +  E+   + G+  +  +     L    E+ +E
Sbjct: 274 SPPPPASRLDDEDGDFQPQEDEEEDDEETIEVEEQQEGNDAEAQRREIELLRREGELPLE 333

Query: 310 KLAKGYQSVTAADPQLPVWPAQEVEDPFGFALEAGCQAWDTKPSIMQSFNDPLLCGKIRP 369
           +L +         P  P       +       E G +  +  P +++          I+P
Sbjct: 334 ELLRSLPPQLLEGPSSPSQTPSSHDSDTRDGPEEGAE--EEPPQVLE----------IKP 381

Query: 370 RKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSH-SSSG 428
              A  +  K PW P  DD           D    ++ A+E ++ +V    ++S  +  G
Sbjct: 382 PPSAVTQRNKQPWHPDEDDEEFTANEEEAEDEEDTIA-AEEQLEGEVDHAMELSELAREG 440

Query: 429 PASVSQL-----------SSWKTPEQPDPVWVQSS---VSGKGEKHPPPRTQLPSSSGKI 474
             S+ +L           S     E  D V   SS     G  E   PP+    S S  +
Sbjct: 441 ELSMEELLQQYAGAYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSV 500


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 98/304 (32%), Positives = 125/304 (41%), Gaps = 41/304 (13%)

Query: 604  GSTGLKAINVEGP-VQGAQALGSSFKPVQAPGSGAPAPAG-ISGSDLQSSGGPLPDARPG 661
            G   ++    +GP VQ  QALG   + +  P S        +S    Q   G L  A+  
Sbjct: 3749 GQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVA 3808

Query: 662  AVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQ--QQS-----HQLVSLQQLQQ 714
             +Q   P  L      P+G     L+     S VL+ PQ  QQ      H+LV+ QQ QQ
Sbjct: 3809 VLQQQHPGALG-----PQGPHRQVLMTQ---SRVLSSPQLAQQGQGLMGHRLVTAQQQQQ 3860

Query: 715  PTAAHPPQPGPQGSALGLSTQGQAFPA---QQLLKVNPTRARSGLQPQPQPAVLSLLGSA 771
                   Q   QGS  GLS   Q+  +   Q  L   P  +   LQ Q Q      L   
Sbjct: 3861 QQ-----QHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQ 3915

Query: 772  QVPQQGVQLPSVLRQQQPQPQPPKLQLQPQWQPKPRQEQPQSQQQQPQHIQLQTQQLRVL 831
            Q  QQ +Q    L+QQQ Q Q  + QLQ Q Q + +Q+Q Q QQQQ Q    Q QQ +  
Sbjct: 3916 Q--QQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQ----QQQQFQQQ 3969

Query: 832  QQPQHIQLQTQQLRVL------QQPVFLATGAVQIVQPH---PGVQVGSQLVDQRKEGKP 882
            QQ Q + L  Q   +L      QQ V L  G       H   PG  +G  L+   KE   
Sbjct: 3970 QQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGA-LGPTLLLTGKEQNT 4028

Query: 883  TPPA 886
              PA
Sbjct: 4029 VDPA 4032



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 107/488 (21%), Positives = 177/488 (36%), Gaps = 54/488 (11%)

Query: 395 PGSETDAGRAVSQAQE------SVQSKVKGPGKMSHSSSGPASVS---QLSS-------- 437
           P  E DA     Q Q       S+Q K  GP +      G A V    QL +        
Sbjct: 381 PTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPL 440

Query: 438 ----WKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAG---SPLK 490
                ++P  P P    +S   +  +  PP  +LP+S    +   S P +++     P +
Sbjct: 441 LPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEE 500

Query: 491 RPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAA 550
            P S     +  +    +  +    + P+PAL    +P   A+        +  +P P  
Sbjct: 501 SPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEE 560

Query: 551 APAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQ---PPTKFIKIAPAIQLRTGSTG 607
            P      A+  S  P  S     P      P P A    PP +   ++P  +    S  
Sbjct: 561 LPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPP 620

Query: 608 LKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPD----ARPGAV 663
            +A  +  P + +     S  P ++P S  P  + +S   + S   P P+    + P   
Sbjct: 621 PEASRLSPPPEDSPM---SPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEE 677

Query: 664 QASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHPPQP 723
             +SP P    L+ P    P +    P+ S     P+     L+SL   + P    P +P
Sbjct: 678 SPTSPPPEASRLSPPPEDSPTS--PPPEDSPASPPPEDS---LMSLPLEESPLLPLPEEP 732

Query: 724 G--PQGSALGLSTQGQA---FPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGV 778
              P+     LS + +     P  +   ++P      L PQP+   L       VP++  
Sbjct: 733 QLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCL-----CAVPEEPH 787

Query: 779 QLPSVLRQQQPQPQPPKLQLQPQWQP---KPRQEQP-QSQQQQPQHIQLQTQQLRVLQQP 834
             P         PQP +L L PQ +     P  E+P  S Q +  H+  Q+++  +  +P
Sbjct: 788 LSPQA-EGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRP 846

Query: 835 QHIQLQTQ 842
           +   L  +
Sbjct: 847 EESHLSPE 854



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 96/447 (21%), Positives = 168/447 (37%), Gaps = 61/447 (13%)

Query: 441 PEQPDPVWVQSSVSGKG-------------EKHP--PPRTQLPSSSGKISSGNSFPPQQA 485
           P++P P+  ++   GK              E+ P  PP  + P S     S  S PP+  
Sbjct: 406 PKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPE-- 463

Query: 486 GSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPA 545
            S L  P     A     A   +     +  +P P  +  + P  ++  +P   +  +P 
Sbjct: 464 ASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPP 523

Query: 546 PAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGS 605
                +PA+    +    A+P        PL       P + PP +  +++P  +     
Sbjct: 524 EESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTS-PPPEASRLSPPPE----E 578

Query: 606 TGLKAINVEGPVQGAQALGSSFKPV-QAPGSGAPAPAGISGSDLQSSGGPLPDARPGAVQ 664
           + +     E P+         F P  ++P S  P  + +S     S   P P+  P    
Sbjct: 579 SPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSP---- 634

Query: 665 ASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPG 724
             SP P +  ++ P  +  L+ L V    + L+ P ++S        L  P    P  P 
Sbjct: 635 -MSPPPEESPMSPPPEVSRLSPLPV---VSRLSPPPEES-------PLSPPPEESPTSPP 683

Query: 725 PQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQLPSVL 784
           P+ S L         P  +    +P    S   P P+ +++SL      P +   L  + 
Sbjct: 684 PEASRLS--------PPPEDSPTSPPPEDSPASPPPEDSLMSL------PLEESPLLPLP 729

Query: 785 RQQQ--PQPQPPKLQLQPQWQP--KPRQEQPQ-SQQQQPQHIQLQTQQ--LRVLQQPQHI 837
            + Q  P+ + P L  +P+ +P   PR E+P  S Q +  H+  Q ++  L  + +  H+
Sbjct: 730 EEPQLCPRSEGPHLSPRPE-EPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHL 788

Query: 838 QLQTQQLRVLQQPVFLATGAVQIVQPH 864
             Q +   +  QP  L   + Q  +PH
Sbjct: 789 SPQAEGPHLSPQPEELHL-SPQTEEPH 814



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 116/529 (21%), Positives = 188/529 (35%), Gaps = 86/529 (16%)

Query: 318 VTAADPQLPVWPAQEVEDPFGFALEAGCQAWDTKPSIMQSFNDPLLCGKIRPRKKARQKS 377
           VT+  P+ P  P Q    P G   +AG Q    +P +    N+ +               
Sbjct: 401 VTSMQPKEP-GPLQCEAKPLG---KAGVQL---EPQLEAPLNEEMPLLPPPEESPLSPPP 453

Query: 378 QKSPWQPFPDDHSACLRPGSETDAG---RAVSQAQESVQSKVKGPGKMSHSSSGPASVSQ 434
           ++SP  P P + S    P  E  A     A+  ++   +S +  P + S  S  P S   
Sbjct: 454 EESPTSP-PPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPES--- 509

Query: 435 LSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFS 494
                    P     +S +S   E  P P  + P S          PP +A SPL  PF 
Sbjct: 510 --------SPFSPLEESPLSPPEESPPSPALETPLS----------PPPEA-SPLSPPFE 550

Query: 495 AAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAV 554
            +           +    A+  +P P  +  + P   +  +P       P  A    P  
Sbjct: 551 ESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSP-------PPEASRLFPPF 603

Query: 555 AAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQ-----PPTKFIKIAPAIQLRTGSTGLK 609
             +P +     P   + P  P  +ASR  P  +     PP +   ++P  ++   S  L 
Sbjct: 604 EESPLS-----PPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSP-LP 657

Query: 610 AINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGAVQASSPA 669
            ++   P      L  S  P ++P S  P  + +S     S   P P+  P     +SP 
Sbjct: 658 VVSRLSPPPEESPL--SPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSP-----ASPP 710

Query: 670 PLQFFLNTPEGLRPLTLL-QVPQGSAVLTGPQ-----QQSHQLVSLQQLQ-QPTAAHP-- 720
           P    ++ P    PL  L + PQ      GP      ++ H     ++    P A  P  
Sbjct: 711 PEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHL 770

Query: 721 -PQPG-------PQGSALGLSTQGQAF-PAQQLLKVNPTRARSGLQPQPQPAVLSLLGSA 771
            PQP        P+   L    +G    P  + L ++P      L P P+   LS     
Sbjct: 771 SPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLS----- 825

Query: 772 QVPQQGVQLPSVLRQQQP--QPQPPKLQLQPQWQPKPRQEQPQSQQQQP 818
             P++    P   + ++P   P+P +  L P+ +  P   +P+   ++P
Sbjct: 826 PQPEESHLSP---QSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEP 871



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 59/205 (28%), Positives = 78/205 (38%), Gaps = 32/205 (15%)

Query: 648  LQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPL---TLLQVPQGSAVLTGPQQQSH 704
            +Q++ GP P      +Q+    P    + T   LR      L + PQ   +    QQQ  
Sbjct: 4164 MQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQ 4223

Query: 705  QLVSLQQLQQPTAAH--PP--QPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQP 760
             L+  +QLQQ  A    PP  +PG Q S           P Q LL   P   + G  P P
Sbjct: 4224 ALLMQRQLQQSQAVRQTPPYQEPGTQTS-----------PLQGLLGCQP---QLGGFPGP 4269

Query: 761  QPAVLSLLGSAQVPQQGVQLPS---------VLRQQQPQPQP--PKLQLQPQWQPKPRQE 809
            Q   L  LG+   PQ   +LP+         VL    P P P  P+   +P   P P  +
Sbjct: 4270 QTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQ 4329

Query: 810  QPQSQQQQPQHIQLQTQQLRVLQQP 834
             P   Q  P H      Q   L+ P
Sbjct: 4330 LPTEAQLPPTHPGTPKPQGPTLEPP 4354



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 71/301 (23%), Positives = 113/301 (37%), Gaps = 44/301 (14%)

Query: 528  PALAAAAAPALAAAAAPAPAPAAAPAV----AAAPAAAASAAPSHSQKPSVPLIQASRPC 583
            PAL     P   A  +P PA  AAP +       PA  +++A    + P+      S P 
Sbjct: 2100 PALHLRIPPQPGALGSPPPA--AAPTIFIGSPTTPAGLSTSADGFLKPPA-----GSVPG 2152

Query: 584  PAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGI 643
            P + P   F+K+ P +  +  S     +    P++          P     +GAPA   +
Sbjct: 2153 PDS-PGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPM 2211

Query: 644  SGSDLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEG-LRP----LTLLQVPQGSAVLTG 698
             G+  +   G     +PG    + P   +   +TP+  L+P    L  L VP+   V  G
Sbjct: 2212 LGASSRPGAG-----QPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGG 2266

Query: 699  PQQQSHQLVSLQQLQQPTAAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQP 758
                        +  +P  + PP         G S +      ++L   +P+     L  
Sbjct: 2267 ------------KASEPLLSPPP--------FGESRKALEVKKEELGASSPSYGPPNLGF 2306

Query: 759  QPQPAVLSLLGSAQVPQQGV-QLPSVLRQQQPQPQPPKLQLQPQWQPKPRQEQPQSQQQQ 817
               P+  + LG  ++    V + P   R  Q +PQ P L L+PQ +P P Q    S    
Sbjct: 2307 VDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQ-EPPPAQALAPSPPSH 2365

Query: 818  P 818
            P
Sbjct: 2366 P 2366



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 102/460 (22%), Positives = 163/460 (35%), Gaps = 45/460 (9%)

Query: 367  IRPRKKARQKSQKSPWQPF-PDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHS 425
            + P+++ +Q+    P  P  P  H +   PG+         + Q +V      P   S +
Sbjct: 3985 LSPQQQQQQQVALGPGMPAKPLQHFSS--PGALGPTLLLTGKEQNTVD-----PAVSSEA 4037

Query: 426  SSGPASVS--QLSSWKTPEQ--PDPVWVQSSVSGKGEK---HPPPRTQLPSSSGKISSGN 478
            + GP++     L+   TPE    +P  V+ S+SG  +     P P+ Q   SS ++    
Sbjct: 4038 TEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQ--PSSLQLQPPL 4095

Query: 479  SFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPA-----LAAA 533
              P QQ         +   +     + +++ A++       P+++    P      L   
Sbjct: 4096 RLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGP 4155

Query: 534  AAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFI 593
              P L         P   P        +    P     P+V  ++A      A+ P +  
Sbjct: 4156 QQPMLERPMQNNTGPQ--PPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNP-QLR 4212

Query: 594  KIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGG 653
             ++P  Q +     L+A+ ++  +Q +QA+  +  P Q PG+      G+ G   Q  G 
Sbjct: 4213 HLSPQQQQQ-----LQALLMQRQLQQSQAVRQT-PPYQEPGTQTSPLQGLLGCQPQLGGF 4266

Query: 654  PLPDARPGAVQASSPAPL--------QFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQ 705
            P P   P     + P P            L+T   L P+     P        P Q    
Sbjct: 4267 PGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSP 4326

Query: 706  LVSLQQLQQPTAAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVL 765
               L    Q    HP  P PQG  L     G+  PA   L    T    GL P   P   
Sbjct: 4327 SSQLPTEAQLPPTHPGTPKPQGPTLE-PPPGRVSPAAAQLA--DTLFSKGLGPWDPP--- 4380

Query: 766  SLLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQLQPQWQPK 805
              L   Q P+Q   +P  L Q   Q  P   QL  + +P+
Sbjct: 4381 DNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPR 4420



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 93/469 (19%), Positives = 163/469 (34%), Gaps = 51/469 (10%)

Query: 378 QKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSS 437
           ++SP  P P++    L P  E+     + ++  S   +      +    S P   S LS 
Sbjct: 490 EESPLSPPPEESP--LSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSP 547

Query: 438 --WKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSA 495
              ++P  P P  + +S   +  +  PP  + P S     S  S PP+   S L  PF  
Sbjct: 548 PFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPE--ASRLFPPFEE 605

Query: 496 AAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVA 555
           +        +  +    A+  +P P  +  + P   +  +P    +     +P    +  
Sbjct: 606 SPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRL---SPLPVVSRL 662

Query: 556 AAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEG 615
           + P   +  +P   + P+ P  +ASR      PP +    +P  +    S   +   +  
Sbjct: 663 SPPPEESPLSPPPEESPTSPPPEASR----LSPPPEDSPTSPPPEDSPASPPPEDSLMSL 718

Query: 616 PVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGAVQASSPAPLQFFL 675
           P++ +  L    +P   P S  P    +S    +    P P+    + QA  P       
Sbjct: 719 PLEESPLLPLPEEPQLCPRSEGPH---LSPRPEEPHLSPRPEEPHLSPQAEEP----HLS 771

Query: 676 NTPEGLRPLTLLQVPQGSAVLTGPQ--QQSHQLVSLQQLQQPTAAHPPQP---GPQGSAL 730
             PE      + + P  S    GP    Q  +L    Q ++P  +  P+     PQ    
Sbjct: 772 PQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEES 831

Query: 731 GLSTQGQA---FPAQQLLKVNPTRARSGLQPQPQ-----------------------PAV 764
            LS Q +     P  +   ++P   +  L P+P+                       P++
Sbjct: 832 HLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSL 891

Query: 765 LSLLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQLQPQWQPKPRQEQPQS 813
             LLG   + + G    S L ++ P     +  L PQ  P      P S
Sbjct: 892 SPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLS 940



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 57/190 (30%), Positives = 68/190 (35%), Gaps = 33/190 (17%)

Query: 688  QVPQGSAVLT-GPQQQSHQLVSLQ-QLQQPTAAHPPQ--PGPQGSALGLSTQGQAFPAQQ 743
            Q  Q SAVL   P Q    L  L  QL       PPQ  PG Q   L L+  G A P Q 
Sbjct: 3609 QQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQP 3668

Query: 744  LLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQLQPQWQ 803
                      + L  Q Q       GS   P  G               P  L L     
Sbjct: 3669 ----GGPFLNTALAQQQQQQHSGGAGSLAGPSGGFF-------------PGNLAL----- 3706

Query: 804  PKPRQEQPQSQQQQPQHIQLQTQQLRVLQQPQHIQLQTQQLRVLQQPVFLATGAVQIVQP 863
               R   P S+  Q + +QLQ Q++++ Q+ Q  Q Q QQ    QQ +       Q  Q 
Sbjct: 3707 ---RSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQ----QQHLLGQVAIQQQQQQ 3759

Query: 864  HPGVQVGSQL 873
             PGVQ    L
Sbjct: 3760 GPGVQTNQAL 3769



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 40/131 (30%), Positives = 51/131 (38%), Gaps = 15/131 (11%)

Query: 693  SAVLTGPQQQSHQLVSLQQ-LQQPTAAHPPQPGPQGSALGLS--TQGQAFPAQQLLKVNP 749
            S  L  PQQQ  Q V+L   +      H   PG  G  L L+   Q    PA     V+ 
Sbjct: 3981 SRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPA-----VSS 4035

Query: 750  TRARSGLQPQPQPAVLSLLGSAQVPQQGVQLPSV-------LRQQQPQPQPPKLQLQPQW 802
                     Q  P  +     +   + G   PS+       L Q QPQPQP  LQLQP  
Sbjct: 4036 EATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPL 4095

Query: 803  QPKPRQEQPQS 813
            +   +Q+Q  S
Sbjct: 4096 RLPGQQQQQVS 4106



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 96/475 (20%), Positives = 170/475 (35%), Gaps = 68/475 (14%)

Query: 402  GRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHP 461
            G  +   Q  + S+    G    SSSG  +  + S   T   P  +   S +SG G    
Sbjct: 3151 GLGLKPGQSMMGSRDTRMGTGPFSSSGHTA-EKASFGATGGPPAHLLTPSPLSGPGGSSL 3209

Query: 462  PPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPA 521
              + +L S +  +  G    P  +G  L +  S+  A                       
Sbjct: 3210 LEKFELESGALTLPGG----PAASGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQ 3265

Query: 522  LAAAAAPALAAAAAPAL-AAAAAPAPAPAAA-PAVAAAPAAAASAAP-----SHSQKPSV 574
            L+A   PA          +  +AP PA A + P   ++P+ A S        + +++P +
Sbjct: 3266 LSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGL 3325

Query: 575  PLIQASRPCPAAQPPTKFI--KIAPAIQLRT-----------GSTGLKAINVEGPVQGAQ 621
            P     +P    QPP   +  ++AP++ + +           G  GL       PV   +
Sbjct: 3326 P-----QPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQK 3380

Query: 622  ALGSS-----FKPVQAPGSGAPAPAGISGSDLQSSGG-----PLPDARPGAVQASSPAPL 671
             +G+       KP Q       A +    +DL          P+  A+  A++       
Sbjct: 3381 PMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMA 3440

Query: 672  QFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSALG 731
            Q  +    G+    +  + Q   +  GP       V+    Q+ +A  P QP P      
Sbjct: 3441 QGSIGVAPGMNRQQVSLLAQ--RLSGGPSSDLQNHVAAGSGQERSAGDPSQPRPNPPTFA 3498

Query: 732  LSTQGQA---------FPAQQLLKVN--PTRARSGLQPQPQPAVLSLLGSA-----QVPQ 775
                 +A         F  QQLL++       + G+  + + A+ +   +A     + P+
Sbjct: 3499 QGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPE 3558

Query: 776  QGVQLPSVLRQQQPQPQPPKLQLQPQ----------WQPKPRQEQPQSQQQQPQH 820
               +   ++ +QQ + Q    Q++ Q          ++ K +Q+Q Q QQQQ QH
Sbjct: 3559 ADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQH 3613



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 112/494 (22%), Positives = 166/494 (33%), Gaps = 73/494 (14%)

Query: 384  PFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQ 443
            P P  H    RPGS TD       AQ  +  + + P   S  +  P S+      + P  
Sbjct: 2360 PSPPSHPDIFRPGSYTD-----PYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPAS 2414

Query: 444  PDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAA------A 497
            P     QS  S +      P T  P S+         P  Q+  P  RP S        A
Sbjct: 2415 P-----QSQSSSQS-----PLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFA 2464

Query: 498  AIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAP---AAAPAV 554
             +           A  A +    +L A   PA   A       A  P+  P     +P  
Sbjct: 2465 PLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGT 2524

Query: 555  AAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPP---TKFIKIAPAI--------QLRT 603
             A     +    +  Q    P ++   P P   PP          P +         + T
Sbjct: 2525 GAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVAT 2584

Query: 604  GSTGLKAINVEGPVQGAQALGSSFKPVQAPG-SGAPAPAG----ISGSDLQSSGGPLPDA 658
            G+       + GP  G+        P++ P     PAP G    +S    Q SG   P  
Sbjct: 2585 GNFHPSGSPL-GPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVE 2643

Query: 659  R---PGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQP 715
            +   PG    SS A  +       G+  L+  ++ +        +Q+  +L+  QQ+Q+ 
Sbjct: 2644 KREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEK-----QRQRQRLRELLIRQQIQRN 2698

Query: 716  T--------AAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNP----TRARSGLQPQPQPA 763
            T        AA     GP GS  G      AF  +QL +       T+ +S L   P P+
Sbjct: 2699 TLRQEKETAAAAAGAVGPPGS-WGAEPSSPAF--EQLSRGQTPFAGTQDKSSLVGLP-PS 2754

Query: 764  VLS--LLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQLQPQWQPKPRQEQPQSQQQQPQHI 821
             LS  +LG    P         L +  P   P  + +  + Q     +    +   P  +
Sbjct: 2755 KLSGPILGPGSFPSD-----DRLSRPPPPATPSSMDVNSR-QLVGGSQAFYQRAPYPGSL 2808

Query: 822  QLQTQQLRVLQQPQ 835
             LQ QQ ++ QQ Q
Sbjct: 2809 PLQQQQQQLWQQQQ 2822



 Score = 35.4 bits (80), Expect = 0.24
 Identities = 86/341 (25%), Positives = 117/341 (34%), Gaps = 33/341 (9%)

Query: 434  QLSSWKTPEQPD--PVWVQSSVSGKGEKHPPPRTQLP-----SSSGKIS-SGNSFPPQQA 485
            +L  +  P +P   P+  + ++S  GE   PP + LP     S SG+ S S    PP   
Sbjct: 879  ELPLFPPPGEPSLSPLLGEPALSEPGE---PPLSPLPEELPLSPSGEPSLSPQLMPPDPL 935

Query: 486  GSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPA 545
              PL  P   AAA  A +          A     P    AA       + P  A    P 
Sbjct: 936  PPPLS-PIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPE 994

Query: 546  PA-PAAAPAVAAAPAAAASAAPSHSQKPSV-PLIQASRPCPAAQPPTKFIKIAPAIQLRT 603
            P  P   P    +P   AS        P   PL+Q S   P   PP++     PA+ L  
Sbjct: 995  PVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSL-VPQNSPPSQC--SPPALPLSV 1051

Query: 604  GSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGAV 663
             S       V G    A+      + V  P   A  P+  + S L S  G L      + 
Sbjct: 1052 PSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPS--ATSPLPSPMGDL------SC 1103

Query: 664  QASSPAP-LQFFLNTPEGLRPLTLLQVP-------QGSAVLTGPQQQSHQLVSLQQLQQP 715
             A SPAP L  F    E   PL  +  P       Q    L    + S  L+  ++L   
Sbjct: 1104 PAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPV 1163

Query: 716  TAAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGL 756
            T         Q +  G   + Q  P   +    PT  +S +
Sbjct: 1164 TPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDI 1204



 Score = 35.4 bits (80), Expect = 0.24
 Identities = 44/141 (31%), Positives = 54/141 (38%), Gaps = 17/141 (12%)

Query: 700  QQQSHQLVSLQQLQQPTAAHP--PQPGPQGSALGLSTQGQA---FPAQQLLKVNPTRARS 754
            QQ S QL   QQ QQ    H     PGP   A+ L  +G +     +QQ L +    AR 
Sbjct: 3264 QQLSAQLQPAQQQQQQQQQHSLLSAPGP-AQAMSLPHEGSSPSLAGSQQQLSLGLAGARQ 3322

Query: 755  GLQPQP----QPAVLSLL-----GSAQVPQQGVQLPSVLRQQQPQPQPPKLQLQPQWQPK 805
               PQP    QP   +L        A V  QG  L      Q      P+   QP    K
Sbjct: 3323 PGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLV--PQQSSQPVLSQK 3380

Query: 806  PRQEQPQSQQQQPQHIQLQTQ 826
            P    P S   +PQ + +Q Q
Sbjct: 3381 PMGTMPPSMCMKPQQLAMQQQ 3401



 Score = 34.3 bits (77), Expect = 0.53
 Identities = 36/109 (33%), Positives = 40/109 (36%), Gaps = 10/109 (9%)

Query: 757  QPQPQPAVLSLLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQ--------LQPQWQPKPRQ 808
            Q Q Q     LLG   + QQ  Q P V   Q   P+P  L         L  Q  P+P Q
Sbjct: 3737 QQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQ 3796

Query: 809  EQPQSQQQQPQHIQLQTQQLRVL-QQPQHIQLQTQQLRVLQQPVFLATG 856
              PQ      Q   LQ Q    L  Q  H Q+   Q RVL  P     G
Sbjct: 3797 -GPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQG 3844



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 34/148 (22%), Positives = 64/148 (43%), Gaps = 20/148 (13%)

Query: 691  QGSAVLTGPQQQSH-QLVSLQQLQQPTAAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNP 749
            Q  AVL G   +S   ++SL + + P    P Q     +   L  +  + P  +      
Sbjct: 4859 QFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPE------ 4912

Query: 750  TRARSGLQPQPQPAVLSLLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQLQPQ-WQPKPRQ 808
                   +P P P+ L+   ++   +  V+LP+    + P P P  L   P+  +PKPR 
Sbjct: 4913 -------EPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRA 4965

Query: 809  EQP-QSQQQQPQHIQ----LQTQQLRVL 831
              P + +  +P  ++    ++ ++LR+L
Sbjct: 4966 RPPEEGEDSRPPRLKKWKGVRWKRLRLL 4993



 Score = 30.4 bits (67), Expect = 7.6
 Identities = 60/293 (20%), Positives = 87/293 (29%), Gaps = 38/293 (12%)

Query: 369  PRKKARQKSQKSPWQPFPDDHSA-CLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSS 427
            P     Q S +SP  P P    A C  P                V  + + P   S   S
Sbjct: 2412 PASPQSQSSSQSPLTPRPLSAEAFCPSP----------------VTPRFQSPDPYSRPPS 2455

Query: 428  GPASVSQLSSWKTPEQPDPVWV--------QSSVSGKGEKHPPPRTQLPSSSGKISSGNS 479
             P S    +    P +P P  V         +S+   G     P         K+ SG  
Sbjct: 2456 RPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQ- 2514

Query: 480  FPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALA 539
             PP    SP    F    +        A    +     P P L             P L 
Sbjct: 2515 -PPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLG 2573

Query: 540  AAAAPAPAPAAA---PAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIA 596
               +     A     P+ +    ++ S   S+   P  P      P P    P     ++
Sbjct: 2574 KPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPY----LS 2629

Query: 597  PAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQ 649
                 R+G T      VE        +GSS    + PG+  P  +G+S ++L+
Sbjct: 2630 HGASQRSGITS----PVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELE 2678


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 125/490 (25%), Positives = 165/490 (33%), Gaps = 101/490 (20%)

Query: 407 QAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQ 466
           + Q+  +S   G G  + S  GP +   L +      P P    +     G         
Sbjct: 72  ELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPG--------- 122

Query: 467 LPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAA-----AAAPAPA 521
                G  S G   PP  A + L  P          + +A AAAAAA          +P 
Sbjct: 123 --GGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180

Query: 522 LAA---AAAPALAAAAAPALAA-----------------AAAPAPAPAAA--------PA 553
           LAA        L   A P   +                 +A P PAPA A        P 
Sbjct: 181 LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240

Query: 554 VAAAPAAAASAAPSHSQKPSVPLIQASR------------------PCPAAQPPTKFIKI 595
             AA AA +   PS S   S      ++                  P P A P    +  
Sbjct: 241 SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT 300

Query: 596 APAIQLRTGSTGLKAINVE-GPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGP 654
           +P+     G  G    +   GP  G    G +    Q  G+ A A A  + S        
Sbjct: 301 SPS--SARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASG------- 351

Query: 655 LPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQ 714
                 GA Q S  AP+    ++  G +PL   + PQ S+    P  Q  ++       Q
Sbjct: 352 ------GAQQRSHHAPMSPG-SSGGGGQPLA--RTPQPSS----PMDQMGKM-----RPQ 393

Query: 715 PTAAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVP 774
           P     P    QG   G   QG  +P Q      P R    +Q + Q A+  L  + Q+P
Sbjct: 394 PYGGTNPYSQQQGPPSG-PQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIP 452

Query: 775 QQGVQLPSVLRQQQPQPQPPKLQLQPQWQPKPRQEQPQSQ--------QQQPQH--IQLQ 824
             G Q PS   QQ   P   +    PQ Q  P  +QP SQ        QQQPQ    QLQ
Sbjct: 453 PYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQ 512

Query: 825 TQQLRVLQQP 834
           + Q    QQP
Sbjct: 513 SSQPPYSQQP 522



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 99/431 (22%), Positives = 138/431 (32%), Gaps = 58/431 (13%)

Query: 442 EQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAA 501
           + P    +QS   G  E +  P+             NS+ P ++  P   P  A A  + 
Sbjct: 177 QSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAP--AYALSSP 234

Query: 502 AAAAAAAAAAAAAAAAPAPALAAAAAPALAAAA----------APALAAAAAPAP----- 546
                 + AAAAA + P P+ +A+A+ + ++ A           P+ A    P P     
Sbjct: 235 RGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPT 294

Query: 547 ------APAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQ 600
                 +P++A      P    S  P        P   AS+   AA         +   Q
Sbjct: 295 LNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQ 354

Query: 601 LRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDAR- 659
            R+    +   +  G  Q          P+   G   P P G +    Q  G P    + 
Sbjct: 355 QRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQG 414

Query: 660 ---PGAVQASS-----PAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQ------SHQ 705
              PG    S      P  +Q    +  G    T    P G    +G  QQ      + Q
Sbjct: 415 HGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQ 474

Query: 706 LVSLQQLQQPTAAHPPQPGP-----------------QGSALGLSTQGQAFPAQQLLKVN 748
               QQ Q P +  PP   P                 Q S    S Q    P QQ     
Sbjct: 475 SPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPY 534

Query: 749 PTRARSGLQ-PQPQPAVLSLLGSAQVPQQGVQ--LPSVLRQQQPQPQPPKLQLQPQWQPK 805
           P++  +  Q PQ QP        +   QQ  Q   PS L QQ   PQP   Q Q     +
Sbjct: 535 PSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQ 594

Query: 806 PRQEQPQSQQQ 816
            R   PQ   Q
Sbjct: 595 QRFPPPQELSQ 605



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 105/476 (22%), Positives = 157/476 (32%), Gaps = 60/476 (12%)

Query: 396 GSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSG 455
           G+   A  A + +  + Q     P  MS  SSG      L+    P  P     +     
Sbjct: 338 GAAAAAAAAAAASGGAQQRSHHAP--MSPGSSGGGG-QPLARTPQPSSPMDQMGKMRPQP 394

Query: 456 KGEKHPPPRTQLPSSSGKISSGNSFPPQQAGS--PLKRPFSAAAAIAAAAAAAAAAAAAA 513
            G  +P  + Q P S  +   G+ +P Q  GS  P + P +           A +A    
Sbjct: 395 YGGTNPYSQQQGPPSGPQ--QGHGYPGQPYGSQTPQRYPMTMQGR-------AQSAMGGL 445

Query: 514 AAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPS 573
           +     P                      +P P     P     P+    A PS+ Q+P 
Sbjct: 446 SYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQ 505

Query: 574 V--PLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQ 631
              P +Q+S+P  + QP     + +PA      ST  +    + P    QA      P Q
Sbjct: 506 SQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQS----PYQ 561

Query: 632 APGSGAPAPAGISGSDLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQ 691
                 PAP+ +S    Q +  P P ++     A S               P  L Q   
Sbjct: 562 QQQPQQPAPSTLS----QQAAYPQPQSQQSQQTAYSQQRFP---------PPQELSQDSF 608

Query: 692 GSAVLTGPQQQSH---QLVSLQQLQQPTAAHPPQPG-----PQGS----ALGLSTQG--- 736
           GS   + P   S    Q      LQ   ++ P   G     P G+    + G+ST G   
Sbjct: 609 GSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISS 668

Query: 737 ----QAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQLPSVLRQQQPQPQ 792
               Q+ PAQ     + +    G++  P P+ +    S    + G   P+ +   Q  P+
Sbjct: 669 SQGEQSNPAQSPFSPHTSPHLPGIRG-PSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPR 727

Query: 793 PPKLQLQPQWQPKPRQEQ-------PQSQQQQPQHIQLQTQQLRVLQQPQHIQLQT 841
           PP  Q      P   Q          Q   Q PQ+   Q       +QP   Q+ T
Sbjct: 728 PPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHT 783



 Score = 30.8 bits (68), Expect = 5.8
 Identities = 81/383 (21%), Positives = 121/383 (31%), Gaps = 78/383 (20%)

Query: 442  EQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAA 501
            E P P    ++ S K +    P+ Q PS +G   SG+   PQ   S      S++ A   
Sbjct: 1111 EDPPPDIFAAADSKKSQ----PKIQPPSPAG---SGSMQGPQTPQST-----SSSMAEGG 1158

Query: 502  AAAAAAAAAAAAAAAAPAPALAAAAAPALAAA----AAPALAAAAAPAPAPAAAPAVAAA 557
                   A+   +   P P ++ + +  +  A    +        +  P P   P++  +
Sbjct: 1159 DLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTS 1218

Query: 558  PAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPV 617
                       S +P+     + R  P + P         + Q   G  G       GP 
Sbjct: 1219 DMMGRM-----SYEPNKDPYGSMRKAPGSDP------FMSSGQGPNGGMGDPYSRAAGPG 1267

Query: 618  QGAQALGS-SFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGAVQASSPAPLQFFLN 676
             G  A+G     P   P        GI      S+G P P+  P    +   +P ++   
Sbjct: 1268 LGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRY--- 1324

Query: 677  TPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSALGLSTQG 736
                                  PQQQ       QQ QQ   ++  Q   QG+  G     
Sbjct: 1325 ---------------------PPQQQ-------QQQQQRHDSYGNQFSTQGTPSGSPFPS 1356

Query: 737  QAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQLPSVLRQQQPQPQPPKL 796
            Q     Q  + N  R   G    P         + +   +   +P    Q QPQ Q    
Sbjct: 1357 QQTTMYQQQQQNYKRPMDGTYGPP---------AKRHEGEMYSVPYSTGQGQPQQQ---- 1403

Query: 797  QLQPQWQPKPRQEQPQSQQQQPQ 819
                  Q  P Q QP SQQQ  Q
Sbjct: 1404 ------QLPPAQPQPASQQQAAQ 1420


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 125/490 (25%), Positives = 165/490 (33%), Gaps = 101/490 (20%)

Query: 407 QAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQ 466
           + Q+  +S   G G  + S  GP +   L +      P P    +     G         
Sbjct: 72  ELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPG--------- 122

Query: 467 LPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAA-----AAAPAPA 521
                G  S G   PP  A + L  P          + +A AAAAAA          +P 
Sbjct: 123 --GGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180

Query: 522 LAA---AAAPALAAAAAPALAA-----------------AAAPAPAPAAA--------PA 553
           LAA        L   A P   +                 +A P PAPA A        P 
Sbjct: 181 LAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240

Query: 554 VAAAPAAAASAAPSHSQKPSVPLIQASR------------------PCPAAQPPTKFIKI 595
             AA AA +   PS S   S      ++                  P P A P    +  
Sbjct: 241 SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT 300

Query: 596 APAIQLRTGSTGLKAINVE-GPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGP 654
           +P+     G  G    +   GP  G    G +    Q  G+ A A A  + S        
Sbjct: 301 SPS--SARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASG------- 351

Query: 655 LPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQ 714
                 GA Q S  AP+    ++  G +PL   + PQ S+    P  Q  ++       Q
Sbjct: 352 ------GAQQRSHHAPMSPG-SSGGGGQPLA--RTPQPSS----PMDQMGKM-----RPQ 393

Query: 715 PTAAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVP 774
           P     P    QG   G   QG  +P Q      P R    +Q + Q A+  L  + Q+P
Sbjct: 394 PYGGTNPYSQQQGPPSG-PQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIP 452

Query: 775 QQGVQLPSVLRQQQPQPQPPKLQLQPQWQPKPRQEQPQSQ--------QQQPQH--IQLQ 824
             G Q PS   QQ   P   +    PQ Q  P  +QP SQ        QQQPQ    QLQ
Sbjct: 453 PYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQ 512

Query: 825 TQQLRVLQQP 834
           + Q    QQP
Sbjct: 513 SSQPPYSQQP 522



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 99/431 (22%), Positives = 138/431 (32%), Gaps = 58/431 (13%)

Query: 442 EQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAA 501
           + P    +QS   G  E +  P+             NS+ P ++  P   P  A A  + 
Sbjct: 177 QSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAP--AYALSSP 234

Query: 502 AAAAAAAAAAAAAAAAPAPALAAAAAPALAAAA----------APALAAAAAPAP----- 546
                 + AAAAA + P P+ +A+A+ + ++ A           P+ A    P P     
Sbjct: 235 RGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPT 294

Query: 547 ------APAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQ 600
                 +P++A      P    S  P        P   AS+   AA         +   Q
Sbjct: 295 LNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQ 354

Query: 601 LRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDAR- 659
            R+    +   +  G  Q          P+   G   P P G +    Q  G P    + 
Sbjct: 355 QRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQG 414

Query: 660 ---PGAVQASS-----PAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQ------SHQ 705
              PG    S      P  +Q    +  G    T    P G    +G  QQ      + Q
Sbjct: 415 HGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQ 474

Query: 706 LVSLQQLQQPTAAHPPQPGP-----------------QGSALGLSTQGQAFPAQQLLKVN 748
               QQ Q P +  PP   P                 Q S    S Q    P QQ     
Sbjct: 475 SPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPY 534

Query: 749 PTRARSGLQ-PQPQPAVLSLLGSAQVPQQGVQ--LPSVLRQQQPQPQPPKLQLQPQWQPK 805
           P++  +  Q PQ QP        +   QQ  Q   PS L QQ   PQP   Q Q     +
Sbjct: 535 PSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQ 594

Query: 806 PRQEQPQSQQQ 816
            R   PQ   Q
Sbjct: 595 QRFPPPQELSQ 605



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 105/476 (22%), Positives = 157/476 (32%), Gaps = 60/476 (12%)

Query: 396 GSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSG 455
           G+   A  A + +  + Q     P  MS  SSG      L+    P  P     +     
Sbjct: 338 GAAAAAAAAAAASGGAQQRSHHAP--MSPGSSGGGG-QPLARTPQPSSPMDQMGKMRPQP 394

Query: 456 KGEKHPPPRTQLPSSSGKISSGNSFPPQQAGS--PLKRPFSAAAAIAAAAAAAAAAAAAA 513
            G  +P  + Q P S  +   G+ +P Q  GS  P + P +           A +A    
Sbjct: 395 YGGTNPYSQQQGPPSGPQ--QGHGYPGQPYGSQTPQRYPMTMQGR-------AQSAMGGL 445

Query: 514 AAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPS 573
           +     P                      +P P     P     P+    A PS+ Q+P 
Sbjct: 446 SYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQ 505

Query: 574 V--PLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQ 631
              P +Q+S+P  + QP     + +PA      ST  +    + P    QA      P Q
Sbjct: 506 SQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQS----PYQ 561

Query: 632 APGSGAPAPAGISGSDLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQ 691
                 PAP+ +S    Q +  P P ++     A S               P  L Q   
Sbjct: 562 QQQPQQPAPSTLS----QQAAYPQPQSQQSQQTAYSQQRFP---------PPQELSQDSF 608

Query: 692 GSAVLTGPQQQSH---QLVSLQQLQQPTAAHPPQPG-----PQGS----ALGLSTQG--- 736
           GS   + P   S    Q      LQ   ++ P   G     P G+    + G+ST G   
Sbjct: 609 GSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISS 668

Query: 737 ----QAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQLPSVLRQQQPQPQ 792
               Q+ PAQ     + +    G++  P P+ +    S    + G   P+ +   Q  P+
Sbjct: 669 SQGEQSNPAQSPFSPHTSPHLPGIRG-PSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPR 727

Query: 793 PPKLQLQPQWQPKPRQEQ-------PQSQQQQPQHIQLQTQQLRVLQQPQHIQLQT 841
           PP  Q      P   Q          Q   Q PQ+   Q       +QP   Q+ T
Sbjct: 728 PPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHT 783


>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
          Length = 780

 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 104/429 (24%), Positives = 154/429 (35%), Gaps = 50/429 (11%)

Query: 389 HSACLRPGSETDAGR-AVSQAQESVQSKVKGP-GKMSHSSSGPASVSQLSSWKTPEQPDP 446
           HS+     +E D+G  A   +   V + ++G  G  S + S   +VSQL   +   QP P
Sbjct: 204 HSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTP 263

Query: 447 VWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNS-FPPQQAGSPLKRPFSAAAAIAAAAAA 505
              QS   G+ +  PPP        G ++  ++  PP    +   +P  AAA      + 
Sbjct: 264 AQPQSFSVGQPQPPPPP------VGGAVAQSSAPLPPFPGAATGPQPMMAAAQ----PSQ 313

Query: 506 AAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAA 565
              A        P     A  A +L     PA+ A AA  P   A P     P       
Sbjct: 314 PQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQ 373

Query: 566 PSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTG-STGLKAINVEGPVQGAQALG 624
           PS   +     +   +P   AQP +     +PA        TG  A +V     GAQ +G
Sbjct: 374 PSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSV-----GAQLMG 428

Query: 625 SSFKPVQA------PGSG---APA-PAGIS----GSDLQSSGGPLPDARPGAV---QASS 667
           +S +P +A      P  G   AP  P G+     G  +Q   GP    +P +V   Q   
Sbjct: 429 ASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGG 488

Query: 668 PAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQG 727
             PL      P  + P     VP   A +  P        S+  +   +   P  P P  
Sbjct: 489 SGPLSAVPGGPHAVVP----GVPNVPAAVPAP--------SVPSVSTTSVTMPNVPAPLA 536

Query: 728 SALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGV--QLPSVLR 785
            +  LS+      +  +++        G    P     S L   Q   Q +  Q+    R
Sbjct: 537 QSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRR 596

Query: 786 QQQPQPQPP 794
           + +P PQPP
Sbjct: 597 KSEPLPQPP 605



 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 93/324 (28%), Positives = 125/324 (38%), Gaps = 60/324 (18%)

Query: 512 AAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAA--APAVAAAPAAAASAAPSHS 569
           AAAAAAPA      +A +++ A A  LAAAA  APAP A   P +A + A   +AAPS  
Sbjct: 95  AAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPGGPQLAGSSAGPVTAAPSQP 154

Query: 570 QKPSVPLIQASRPCPAAQPPTKFIKIA----------PAIQLRTGSTGLKAINVEGPVQ- 618
                   +  +    +  P +  +             ++  R+G     +   +   + 
Sbjct: 155 PTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAER 214

Query: 619 --GAQALGSSFKPVQAPGSGAPAPAGISGSDLQ----------------------SSGGP 654
             G  A G S   V A   GA  P   + S L                       S G P
Sbjct: 215 DSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQP 274

Query: 655 LPDARP-GAVQASSPAPLQFFLNTPEGLRPLTLL---QVPQGSAVLTGPQQQSHQLVSLQ 710
            P   P G   A S APL  F     G +P+        PQG+    GP  Q+    ++ 
Sbjct: 275 QPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGA----GPGGQTLPPTNV- 329

Query: 711 QLQQPTAAHPPQPGPQ-GSALGLSTQGQAFPAQQ-----LLKVNPT-------RARSGLQ 757
            L QP  + PPQPGP  G+      Q  A+P  Q     LL V P+       +  +GLQ
Sbjct: 330 TLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQ 389

Query: 758 PQPQPAVLSLLGSAQVPQQGVQLP 781
           P P PA  S  G+A  P     LP
Sbjct: 390 P-PSPAQPSSTGAAASPATAATLP 412


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 67.4 bits (163), Expect = 6e-11
 Identities = 86/344 (25%), Positives = 127/344 (36%), Gaps = 46/344 (13%)

Query: 518  PAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLI 577
            P+P  A    P    +        A P P+P +  + A  P+ A +  P+ +     P  
Sbjct: 1845 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSM-SPAGFPSVARTQPPT-TVSTGKPTS 1902

Query: 578  QASRPCPAAQPPTKFIKIAPAIQLRTGSTG-LKAINVEGPVQ-GAQALGSSFKPVQAPGS 635
            Q   P P AQPP   ++ A  I+        L  +N+   +  G   +G+    +     
Sbjct: 1903 QVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSL 1962

Query: 636  GAPAPAGISGSDLQS------SGGPLPDARPGA----------VQASSPAPLQFFLNTPE 679
              P P  +SG  + S         PLP  +P             QA+   P    +  P 
Sbjct: 1963 NVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPR 2022

Query: 680  GLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSALGLSTQGQAF 739
             + P  L  + +     + PQQQ   L  L+   Q  AA   Q     +A  ++ Q    
Sbjct: 2023 SISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQR----TAKYVANQPGMQ 2078

Query: 740  PAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQLPSVLRQQQ------PQPQ- 792
            P   L      +++ G+QPQP       L +    Q GV  P V  QQQ      PQ Q 
Sbjct: 2079 PQPGL------QSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQA 2132

Query: 793  ---------PPKLQLQPQWQPKPRQEQPQSQQQQPQHIQLQTQQ 827
                     P    + PQ++   R++  Q QQQQ Q  Q Q QQ
Sbjct: 2133 LNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQ 2176



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 137/600 (22%), Positives = 193/600 (32%), Gaps = 114/600 (19%)

Query: 356  QSFNDPLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSK 415
            Q     L   ++  R+ A   ++  P Q  P   SA   PG+ T         Q   Q +
Sbjct: 1815 QQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSA--PPGTPTQQPSTPQTPQPPAQPQ 1872

Query: 416  VKGPGKMSHSSSGPASV---------------SQLSSWKTPEQPDPVWVQSSVSGKGEKH 460
               P  +S S +G  SV               SQ+ +   P QP P  V+++   + E  
Sbjct: 1873 ---PSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIERE-- 1927

Query: 461  PPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAP-- 518
                 Q      +++  NS PP + G  +  P S  A ++         +     + P  
Sbjct: 1928 ----AQQQQHLYRVNINNSMPPGRTG--MGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPG 1981

Query: 519  ----APALAAAAAPALAAAAAPALAAAAAPAPA-PAAAPAVAAAPAA------AASAAPS 567
                AP       P L        A AA   P  P+  P  + +P+A         +  S
Sbjct: 1982 QWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSS 2041

Query: 568  HSQKPSVPLIQASRPCPAA----QPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQAL 623
              Q+  V  I  S P   A    Q   K++   P +Q               P  G Q+ 
Sbjct: 2042 PQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQ---------------PQPGLQS- 2085

Query: 624  GSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGAVQASSPAPLQFFLNTPE-GLR 682
                +P   P  G      +   +   +G P P   P         P    LN    G  
Sbjct: 2086 ----QPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHN 2141

Query: 683  PLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSALGLSTQGQ----- 737
            P      PQ   +L     Q  Q    QQ QQ       Q G  G A G++  GQ     
Sbjct: 2142 PNMASMNPQYREMLRRQLLQQQQ----QQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQ 2197

Query: 738  ---AFPA--QQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQ----LPSVLRQQQ 788
                +P   QQ  ++       G       A +  LG    P  G      +   L+Q+ 
Sbjct: 2198 GPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRI 2257

Query: 789  PQPQPPKLQLQPQWQPKPRQEQPQSQQQQPQHIQLQTQQL-----------------RVL 831
             Q Q  K Q+    QP P   Q      QPQ   L  QQ+                 R  
Sbjct: 2258 LQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQ 2317

Query: 832  QQPQHIQLQTQQLRVLQQP----VFLATGAVQIVQPHPGVQVG-SQLVDQRKEGKPTPPA 886
             QP H    +   R+  QP    V   TG+     PHPG+ V  +  +DQ   G P   A
Sbjct: 2318 SQPPH---SSPSPRIQPQPSPHHVSPQTGS-----PHPGLAVTMASSIDQGHLGNPEQSA 2369



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 83/424 (19%), Positives = 143/424 (33%), Gaps = 86/424 (20%)

Query: 422  MSHS----SSGPASVSQLSSWKTPEQPDPVWVQSS---VSGKGEKHPPPRTQLPSSSGKI 474
            M+HS    S G      +S  + P+ P+ +   ++        +    P+ Q PSSSG +
Sbjct: 709  MNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAM 768

Query: 475  SSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAA 534
            S G   PP Q G    +   AA           A+         +P L     PA  AA 
Sbjct: 769  SVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSP-LHPTPPPASTAAG 827

Query: 535  APALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIK 594
             P+L     P   P       AAP   ++   S  Q P+        P P + P     +
Sbjct: 828  MPSLQHTTPPGMTPPQP----AAPTQPSTPVSSSGQTPT--------PTPGSVPSATQTQ 875

Query: 595  IAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGP 654
              P +Q                   AQ       PVQ P    P  +       Q    P
Sbjct: 876  STPTVQ---------------AAAQAQVTPQPQTPVQPPSVATPQSS-------QQQPTP 913

Query: 655  LPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQ 714
            +    PG   + + A +   + TP  +           ++  T  Q              
Sbjct: 914  VHAQPPGTPLSQAAASIDNRVPTPSSV-----------ASAETNSQ-------------- 948

Query: 715  PTAAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVP 774
                   QPGP    L + T+ QA   +      P    S  +P+ +     L G++QV 
Sbjct: 949  -------QPGPDVPVLEMKTETQAEDTE------PDPGESKGEPRSEMMEEDLQGASQVK 995

Query: 775  QQGVQLPSVLRQQQPQPQPPKLQLQPQWQPKPRQEQPQSQQQQPQHIQLQTQQLRVLQQP 834
            ++     + + +Q+ +P     + +P+ + + ++E+  S           +Q  + + +P
Sbjct: 996  EE-----TDIAEQKSEPMEVD-EKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKP 1049

Query: 835  QHIQ 838
            + ++
Sbjct: 1050 EELR 1053



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 87/360 (24%), Positives = 122/360 (33%), Gaps = 84/360 (23%)

Query: 578 QASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPV------- 630
           Q + P P AQPP   I  A  ++   G   L        +Q +Q + +SF P+       
Sbjct: 644 QPALPAPGAQPPV--IPQAQPVRPPNGPLSLPV----NRMQVSQGM-NSFNPMSLGNVQL 696

Query: 631 -QAP-GSGAPAP----------AGISGSDLQSSGGPLPDARPGA----VQASSPAPLQFF 674
            QAP G  A +P            + G  +  S  P P    GA    + A +PA  QF 
Sbjct: 697 PQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFL 756

Query: 675 LNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHP-------------- 720
              P+        Q P  S  ++    Q      + Q Q P AA P              
Sbjct: 757 ---PQN-------QFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLP 806

Query: 721 ----------PQPGPQGSALGL-----STQGQAFPAQQLLKVNPTRARSGLQPQPQPAVL 765
                     P P P  +A G+     +T     P Q      P+   S     P P   
Sbjct: 807 CPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPG 866

Query: 766 SLLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQLQPQWQPKPRQEQPQSQQQQPQHIQLQT 825
           S+  + Q         +   Q  PQPQ P   +QP     P    PQS QQQP  +  Q 
Sbjct: 867 SVPSATQTQSTPTVQAAAQAQVTPQPQTP---VQP-----PSVATPQSSQQQPTPVHAQP 918

Query: 826 QQLRVLQQPQHIQLQTQQLRVLQQPVFLATGAVQIVQPHPGVQVGSQLVD-QRKEGKPTP 884
               + Q    I  +      +  P  +A+      QP P V V     + Q ++ +P P
Sbjct: 919 PGTPLSQAAASIDNR------VPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDP 972



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 76/304 (25%), Positives = 110/304 (36%), Gaps = 41/304 (13%)

Query: 535 APALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIK 594
           AP    AA+P        ++ + P  A S  PS   +P   ++ A      AQ P +  +
Sbjct: 699 APMGPRAASPMNHSVQMNSMGSVPGMAIS--PSRMPQPP-NMMGAHTNNMMAQAPAQS-Q 754

Query: 595 IAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQS---- 650
             P  Q  + S  +     + P Q   + G      Q PG+  P P  + G         
Sbjct: 755 FLPQNQFPSSSGAMSVGMGQPPAQTGVSQG------QVPGAALPNPLNMLGPQASQLPCP 808

Query: 651 --SGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVS 708
             +  PL    P A  A+    LQ    TP G+ P      PQ +A    P Q S  + S
Sbjct: 809 PVTQSPLHPTPPPASTAAGMPSLQH--TTPPGMTP------PQPAA----PTQPSTPVSS 856

Query: 709 LQQLQQPTAAHPPQPGPQGSA--LGLSTQGQAFPAQQLLKVNPTRAR---SGLQPQP--- 760
             Q   PT    P      S   +  + Q Q  P  Q     P+ A    S  QP P   
Sbjct: 857 SGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHA 916

Query: 761 QPAVLSLLGSAQVPQQGVQLPSVL-----RQQQPQPQPPKLQLQPQWQPKPRQEQPQSQQ 815
           QP    L  +A      V  PS +       QQP P  P L+++ + Q +  +  P   +
Sbjct: 917 QPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESK 976

Query: 816 QQPQ 819
            +P+
Sbjct: 977 GEPR 980



 Score = 31.2 bits (69), Expect = 4.5
 Identities = 48/223 (21%), Positives = 77/223 (34%), Gaps = 28/223 (12%)

Query: 372 KARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPAS 431
           +A  +SQ  P   FP    A      +  A   VSQ Q      V G    +  +     
Sbjct: 748 QAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQ------VPGAALPNPLNMLGPQ 801

Query: 432 VSQLSS---WKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSP 488
            SQL      ++P  P P    ++      +H  P    P      +  ++       +P
Sbjct: 802 ASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTP 861

Query: 489 LKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAP 548
              P S  +A     +     AAA A   P P       P    + A   ++   P P  
Sbjct: 862 TPTPGSVPSA-TQTQSTPTVQAAAQAQVTPQPQ-----TPVQPPSVATPQSSQQQPTPVH 915

Query: 549 AAAPAVAAAPAAAA-----------SAAPSHSQK--PSVPLIQ 578
           A  P    + AAA+           ++A ++SQ+  P VP+++
Sbjct: 916 AQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLE 958


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 67.4 bits (163), Expect = 6e-11
 Identities = 86/344 (25%), Positives = 127/344 (36%), Gaps = 46/344 (13%)

Query: 518  PAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLI 577
            P+P  A    P    +        A P P+P +  + A  P+ A +  P+ +     P  
Sbjct: 1883 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSM-SPAGFPSVARTQPPT-TVSTGKPTS 1940

Query: 578  QASRPCPAAQPPTKFIKIAPAIQLRTGSTG-LKAINVEGPVQ-GAQALGSSFKPVQAPGS 635
            Q   P P AQPP   ++ A  I+        L  +N+   +  G   +G+    +     
Sbjct: 1941 QVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSL 2000

Query: 636  GAPAPAGISGSDLQS------SGGPLPDARPGA----------VQASSPAPLQFFLNTPE 679
              P P  +SG  + S         PLP  +P             QA+   P    +  P 
Sbjct: 2001 NVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPR 2060

Query: 680  GLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSALGLSTQGQAF 739
             + P  L  + +     + PQQQ   L  L+   Q  AA   Q     +A  ++ Q    
Sbjct: 2061 SISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQR----TAKYVANQPGMQ 2116

Query: 740  PAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQLPSVLRQQQ------PQPQ- 792
            P   L      +++ G+QPQP       L +    Q GV  P V  QQQ      PQ Q 
Sbjct: 2117 PQPGL------QSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQA 2170

Query: 793  ---------PPKLQLQPQWQPKPRQEQPQSQQQQPQHIQLQTQQ 827
                     P    + PQ++   R++  Q QQQQ Q  Q Q QQ
Sbjct: 2171 LNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQ 2214



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 137/600 (22%), Positives = 193/600 (32%), Gaps = 114/600 (19%)

Query: 356  QSFNDPLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSK 415
            Q     L   ++  R+ A   ++  P Q  P   SA   PG+ T         Q   Q +
Sbjct: 1853 QQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSA--PPGTPTQQPSTPQTPQPPAQPQ 1910

Query: 416  VKGPGKMSHSSSGPASV---------------SQLSSWKTPEQPDPVWVQSSVSGKGEKH 460
               P  +S S +G  SV               SQ+ +   P QP P  V+++   + E  
Sbjct: 1911 ---PSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIERE-- 1965

Query: 461  PPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAP-- 518
                 Q      +++  NS PP + G  +  P S  A ++         +     + P  
Sbjct: 1966 ----AQQQQHLYRVNINNSMPPGRTG--MGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPG 2019

Query: 519  ----APALAAAAAPALAAAAAPALAAAAAPAPA-PAAAPAVAAAPAA------AASAAPS 567
                AP       P L        A AA   P  P+  P  + +P+A         +  S
Sbjct: 2020 QWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSS 2079

Query: 568  HSQKPSVPLIQASRPCPAA----QPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQAL 623
              Q+  V  I  S P   A    Q   K++   P +Q               P  G Q+ 
Sbjct: 2080 PQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQ---------------PQPGLQS- 2123

Query: 624  GSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGAVQASSPAPLQFFLNTPE-GLR 682
                +P   P  G      +   +   +G P P   P         P    LN    G  
Sbjct: 2124 ----QPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHN 2179

Query: 683  PLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSALGLSTQGQ----- 737
            P      PQ   +L     Q  Q    QQ QQ       Q G  G A G++  GQ     
Sbjct: 2180 PNMASMNPQYREMLRRQLLQQQQ----QQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQ 2235

Query: 738  ---AFPA--QQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQ----LPSVLRQQQ 788
                +P   QQ  ++       G       A +  LG    P  G      +   L+Q+ 
Sbjct: 2236 GPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRI 2295

Query: 789  PQPQPPKLQLQPQWQPKPRQEQPQSQQQQPQHIQLQTQQL-----------------RVL 831
             Q Q  K Q+    QP P   Q      QPQ   L  QQ+                 R  
Sbjct: 2296 LQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQ 2355

Query: 832  QQPQHIQLQTQQLRVLQQP----VFLATGAVQIVQPHPGVQVG-SQLVDQRKEGKPTPPA 886
             QP H    +   R+  QP    V   TG+     PHPG+ V  +  +DQ   G P   A
Sbjct: 2356 SQPPH---SSPSPRIQPQPSPHHVSPQTGS-----PHPGLAVTMASSIDQGHLGNPEQSA 2407



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 83/424 (19%), Positives = 143/424 (33%), Gaps = 86/424 (20%)

Query: 422  MSHS----SSGPASVSQLSSWKTPEQPDPVWVQSS---VSGKGEKHPPPRTQLPSSSGKI 474
            M+HS    S G      +S  + P+ P+ +   ++        +    P+ Q PSSSG +
Sbjct: 747  MNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAM 806

Query: 475  SSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAA 534
            S G   PP Q G    +   AA           A+         +P L     PA  AA 
Sbjct: 807  SVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSP-LHPTPPPASTAAG 865

Query: 535  APALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIK 594
             P+L     P   P       AAP   ++   S  Q P+        P P + P     +
Sbjct: 866  MPSLQHTTPPGMTPPQP----AAPTQPSTPVSSSGQTPT--------PTPGSVPSATQTQ 913

Query: 595  IAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGP 654
              P +Q                   AQ       PVQ P    P  +       Q    P
Sbjct: 914  STPTVQ---------------AAAQAQVTPQPQTPVQPPSVATPQSS-------QQQPTP 951

Query: 655  LPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQ 714
            +    PG   + + A +   + TP  +           ++  T  Q              
Sbjct: 952  VHAQPPGTPLSQAAASIDNRVPTPSSV-----------ASAETNSQ-------------- 986

Query: 715  PTAAHPPQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVP 774
                   QPGP    L + T+ QA   +      P    S  +P+ +     L G++QV 
Sbjct: 987  -------QPGPDVPVLEMKTETQAEDTE------PDPGESKGEPRSEMMEEDLQGASQVK 1033

Query: 775  QQGVQLPSVLRQQQPQPQPPKLQLQPQWQPKPRQEQPQSQQQQPQHIQLQTQQLRVLQQP 834
            ++     + + +Q+ +P     + +P+ + + ++E+  S           +Q  + + +P
Sbjct: 1034 EE-----TDIAEQKSEPMEVD-EKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKP 1087

Query: 835  QHIQ 838
            + ++
Sbjct: 1088 EELR 1091



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 87/360 (24%), Positives = 122/360 (33%), Gaps = 84/360 (23%)

Query: 578  QASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPV------- 630
            Q + P P AQPP   I  A  ++   G   L        +Q +Q + +SF P+       
Sbjct: 682  QPALPAPGAQPPV--IPQAQPVRPPNGPLSLPV----NRMQVSQGM-NSFNPMSLGNVQL 734

Query: 631  -QAP-GSGAPAP----------AGISGSDLQSSGGPLPDARPGA----VQASSPAPLQFF 674
             QAP G  A +P            + G  +  S  P P    GA    + A +PA  QF 
Sbjct: 735  PQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFL 794

Query: 675  LNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHP-------------- 720
               P+        Q P  S  ++    Q      + Q Q P AA P              
Sbjct: 795  ---PQN-------QFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLP 844

Query: 721  ----------PQPGPQGSALGL-----STQGQAFPAQQLLKVNPTRARSGLQPQPQPAVL 765
                      P P P  +A G+     +T     P Q      P+   S     P P   
Sbjct: 845  CPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPG 904

Query: 766  SLLGSAQVPQQGVQLPSVLRQQQPQPQPPKLQLQPQWQPKPRQEQPQSQQQQPQHIQLQT 825
            S+  + Q         +   Q  PQPQ P   +QP     P    PQS QQQP  +  Q 
Sbjct: 905  SVPSATQTQSTPTVQAAAQAQVTPQPQTP---VQP-----PSVATPQSSQQQPTPVHAQP 956

Query: 826  QQLRVLQQPQHIQLQTQQLRVLQQPVFLATGAVQIVQPHPGVQVGSQLVD-QRKEGKPTP 884
                + Q    I  +      +  P  +A+      QP P V V     + Q ++ +P P
Sbjct: 957  PGTPLSQAAASIDNR------VPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDP 1010



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 76/304 (25%), Positives = 110/304 (36%), Gaps = 41/304 (13%)

Query: 535  APALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIK 594
            AP    AA+P        ++ + P  A S  PS   +P   ++ A      AQ P +  +
Sbjct: 737  APMGPRAASPMNHSVQMNSMGSVPGMAIS--PSRMPQPP-NMMGAHTNNMMAQAPAQS-Q 792

Query: 595  IAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQS---- 650
              P  Q  + S  +     + P Q   + G      Q PG+  P P  + G         
Sbjct: 793  FLPQNQFPSSSGAMSVGMGQPPAQTGVSQG------QVPGAALPNPLNMLGPQASQLPCP 846

Query: 651  --SGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVS 708
              +  PL    P A  A+    LQ    TP G+ P      PQ +A    P Q S  + S
Sbjct: 847  PVTQSPLHPTPPPASTAAGMPSLQH--TTPPGMTP------PQPAA----PTQPSTPVSS 894

Query: 709  LQQLQQPTAAHPPQPGPQGSA--LGLSTQGQAFPAQQLLKVNPTRAR---SGLQPQP--- 760
              Q   PT    P      S   +  + Q Q  P  Q     P+ A    S  QP P   
Sbjct: 895  SGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHA 954

Query: 761  QPAVLSLLGSAQVPQQGVQLPSVL-----RQQQPQPQPPKLQLQPQWQPKPRQEQPQSQQ 815
            QP    L  +A      V  PS +       QQP P  P L+++ + Q +  +  P   +
Sbjct: 955  QPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESK 1014

Query: 816  QQPQ 819
             +P+
Sbjct: 1015 GEPR 1018



 Score = 31.2 bits (69), Expect = 4.5
 Identities = 48/223 (21%), Positives = 77/223 (34%), Gaps = 28/223 (12%)

Query: 372 KARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPAS 431
           +A  +SQ  P   FP    A      +  A   VSQ Q      V G    +  +     
Sbjct: 786 QAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQ------VPGAALPNPLNMLGPQ 839

Query: 432 VSQLSS---WKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSP 488
            SQL      ++P  P P    ++      +H  P    P      +  ++       +P
Sbjct: 840 ASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTP 899

Query: 489 LKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAP 548
              P S  +A     +     AAA A   P P       P    + A   ++   P P  
Sbjct: 900 TPTPGSVPSA-TQTQSTPTVQAAAQAQVTPQPQ-----TPVQPPSVATPQSSQQQPTPVH 953

Query: 549 AAAPAVAAAPAAAA-----------SAAPSHSQK--PSVPLIQ 578
           A  P    + AAA+           ++A ++SQ+  P VP+++
Sbjct: 954 AQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLE 996


>gi|169211815 PREDICTED: keratin associated protein 4.6 [Homo
           sapiens]
          Length = 288

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 66/209 (31%), Positives = 91/209 (43%), Gaps = 21/209 (10%)

Query: 478 NSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPA 537
           N +P     +P+  P +   A+A   AAA AA    AA  PA A  AA  PA A  +A +
Sbjct: 73  NLYPLTPWSAPVVVPSALTRAVAWRPAAAPAAVRPPAAGPPAAA-PAAVCPAAADPSAAS 131

Query: 538 LAAAAAPAPAPAAAPA-----VAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKF 592
           L AA+ PA  PAA PA      A  PAAA +A    +  PS   + A+ P  A       
Sbjct: 132 LCAASPPAAVPAAVPAAVRPPAAGPPAAALAAVYPAAADPSAASLCAASPLAAVPAAASP 191

Query: 593 IKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAP----------GSGAPAPAG 642
             +APA  +  G+ G  A ++    Q A    ++     AP           + APA A 
Sbjct: 192 AAVAPA-AVCPGAAGPSAASLCAASQPAAVPAAASPAAAAPLAVNPAAAARAAAAPAAAC 250

Query: 643 ISGSDLQSSGGPLPDARPGAVQASSPAPL 671
           +  S  +S   PL  A+P    +  PAP+
Sbjct: 251 VQ-SVAESPATPLAIAQP---VSFPPAPV 275



 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 53/131 (40%), Positives = 65/131 (49%), Gaps = 23/131 (17%)

Query: 482 PQQAGSP---LKRPFSAAAAIAAAAAAAAAAAAAA-AAAAPAPALAAAAAPALAAAAAPA 537
           P  AG P   L   + AAA  +AA+  AA+  AA  AAA+PA    AA  P  A  +A +
Sbjct: 151 PPAAGPPAAALAAVYPAAADPSAASLCAASPLAAVPAAASPAAVAPAAVCPGAAGPSAAS 210

Query: 538 LAAAAAPAPAPAAAPAVAAAP-------AAAASAAP------SHSQKPSVPLIQAS---- 580
           L AA+ PA  PAAA   AAAP       AA A+AAP      S ++ P+ PL  A     
Sbjct: 211 LCAASQPAAVPAAASPAAAAPLAVNPAAAARAAAAPAAACVQSVAESPATPLAIAQPVSF 270

Query: 581 --RPCPAAQPP 589
              P P A PP
Sbjct: 271 PPAPVPCAVPP 281



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 75/252 (29%), Positives = 100/252 (39%), Gaps = 25/252 (9%)

Query: 395 PGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVS 454
           P    D  R  S   E+ + K +G      S     ++  L+ W  P     V V S+++
Sbjct: 42  PPMSHDTQRLKSCDTETKERKTRGD-----SCGNTRNLYPLTPWSAP-----VVVPSALT 91

Query: 455 GKGEKHPP--PRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAA 512
                 P   P    P ++G  ++  +     A  P      AA+  AA  AA  AA   
Sbjct: 92  RAVAWRPAAAPAAVRPPAAGPPAAAPAAVCPAAADPSAASLCAASPPAAVPAAVPAAVRP 151

Query: 513 AAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKP 572
            AA  PA AL AA  PA A  +A +L AA+  A  PAAA   A APAA    A   S   
Sbjct: 152 PAAGPPAAAL-AAVYPAAADPSAASLCAASPLAAVPAAASPAAVAPAAVCPGAAGPS--- 207

Query: 573 SVPLIQASRPC--PAAQPPTKFIKIA--PAIQLRTGSTGLKAINVEGPVQGAQALGSSFK 628
           +  L  AS+P   PAA  P     +A  PA   R  +    A      VQ      ++  
Sbjct: 208 AASLCAASQPAAVPAAASPAAAAPLAVNPAAAARAAAAPAAAC-----VQSVAESPATPL 262

Query: 629 PVQAPGSGAPAP 640
            +  P S  PAP
Sbjct: 263 AIAQPVSFPPAP 274



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 39/104 (37%), Positives = 49/104 (47%), Gaps = 10/104 (9%)

Query: 463 PRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPAL 522
           P   +P+++   +   +     A  P      AA+  AA  AAA+ AAAA  A  PA A 
Sbjct: 181 PLAAVPAAASPAAVAPAAVCPGAAGPSAASLCAASQPAAVPAAASPAAAAPLAVNPAAAA 240

Query: 523 AAAAAPALA----AAAAPALAAAAA------PAPAPAAAPAVAA 556
            AAAAPA A     A +PA   A A      PAP P A P +AA
Sbjct: 241 RAAAAPAAACVQSVAESPATPLAIAQPVSFPPAPVPCAVPPLAA 284



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 46/176 (26%), Positives = 62/176 (35%), Gaps = 17/176 (9%)

Query: 629 PVQAPGSGAPAPAGISGSDLQSSGGP--LPDARPGAVQ--ASSPAPLQFFLNTPEGLRPL 684
           P  AP +  PA A  S + L ++  P  +P A P AV+  A+ P         P    P 
Sbjct: 113 PAAAPAAVCPAAADPSAASLCAASPPAAVPAAVPAAVRPPAAGPPAAALAAVYPAAADP- 171

Query: 685 TLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSALGLSTQGQAFPAQQL 744
           +   +   S +   P   S   V+      P A  P   GP  ++L  ++Q  A PA   
Sbjct: 172 SAASLCAASPLAAVPAAASPAAVA------PAAVCPGAAGPSAASLCAASQPAAVPAAAS 225

Query: 745 ------LKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQLPSVLRQQQPQPQPP 794
                 L VNP  A           V S+  S   P    Q  S      P   PP
Sbjct: 226 PAAAAPLAVNPAAAARAAAAPAAACVQSVAESPATPLAIAQPVSFPPAPVPCAVPP 281


>gi|110347459 MYC-associated zinc finger protein isoform 2 [Homo
           sapiens]
          Length = 493

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 55/133 (41%), Positives = 67/133 (50%), Gaps = 23/133 (17%)

Query: 481 PPQQAGSPLK---RPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPA 537
           P   A  PL+    P  AAA  +AAAAAAAAAAAAA AAAP PA AAA+    AA   P 
Sbjct: 73  PQAPAAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVAAAP-PAPAAASTVDTAALKQP- 130

Query: 538 LAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAP 597
              A  P P P +APA  AAP A+A+               A+    A   PT  + +AP
Sbjct: 131 --PAPPPPPPPVSAPAAEAAPPASAATI-------------AAAAATAVVAPTSTVAVAP 175

Query: 598 ---AIQLRTGSTG 607
              A++ +T S G
Sbjct: 176 VASALEKKTKSKG 188



 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 50/148 (33%), Positives = 59/148 (39%), Gaps = 14/148 (9%)

Query: 453 VSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAA 512
           V G     PPP+            G++  P Q G+ L+  F A+   A +   AA A   
Sbjct: 24  VGGLMNSFPPPQ------------GHAQNPLQVGAELQSRFFASQGCAQSPFQAAPAPPP 71

Query: 513 AAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAP--AAAPAVAAAPAAAASAAPSHSQ 570
              A  A  L     P LAAA   A AAAAA A A   AAAP   AA +   +AA     
Sbjct: 72  TPQAPAAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVAAAPPAPAAASTVDTAALKQPP 131

Query: 571 KPSVPLIQASRPCPAAQPPTKFIKIAPA 598
            P  P    S P   A PP     IA A
Sbjct: 132 APPPPPPPVSAPAAEAAPPASAATIAAA 159



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 55/136 (40%), Positives = 64/136 (47%), Gaps = 35/136 (25%)

Query: 461 PPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAP 520
           PPP  Q P++           P Q    L    +AA   AAAAAAAAAAAAA AAA PAP
Sbjct: 69  PPPTPQAPAAE----------PLQVD--LLPVLAAAQESAAAAAAAAAAAAAVAAAPPAP 116

Query: 521 ALAAA-------------------AAPALAAAAAPALAAAAAPAPAPA-AAP--AVAAAP 558
           A A+                    +APA A AA PA AA  A A A A  AP   VA AP
Sbjct: 117 AAASTVDTAALKQPPAPPPPPPPVSAPA-AEAAPPASAATIAAAAATAVVAPTSTVAVAP 175

Query: 559 AAAASAAPSHSQKPSV 574
            A+A    + S+ P +
Sbjct: 176 VASALEKKTKSKGPYI 191


>gi|110347461 MYC-associated zinc finger protein isoform 1 [Homo
           sapiens]
          Length = 477

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 55/133 (41%), Positives = 67/133 (50%), Gaps = 23/133 (17%)

Query: 481 PPQQAGSPLK---RPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPA 537
           P   A  PL+    P  AAA  +AAAAAAAAAAAAA AAAP PA AAA+    AA   P 
Sbjct: 73  PQAPAAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVAAAP-PAPAAASTVDTAALKQP- 130

Query: 538 LAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAP 597
              A  P P P +APA  AAP A+A+               A+    A   PT  + +AP
Sbjct: 131 --PAPPPPPPPVSAPAAEAAPPASAATI-------------AAAAATAVVAPTSTVAVAP 175

Query: 598 ---AIQLRTGSTG 607
              A++ +T S G
Sbjct: 176 VASALEKKTKSKG 188



 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 50/148 (33%), Positives = 59/148 (39%), Gaps = 14/148 (9%)

Query: 453 VSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAA 512
           V G     PPP+            G++  P Q G+ L+  F A+   A +   AA A   
Sbjct: 24  VGGLMNSFPPPQ------------GHAQNPLQVGAELQSRFFASQGCAQSPFQAAPAPPP 71

Query: 513 AAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAP--AAAPAVAAAPAAAASAAPSHSQ 570
              A  A  L     P LAAA   A AAAAA A A   AAAP   AA +   +AA     
Sbjct: 72  TPQAPAAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVAAAPPAPAAASTVDTAALKQPP 131

Query: 571 KPSVPLIQASRPCPAAQPPTKFIKIAPA 598
            P  P    S P   A PP     IA A
Sbjct: 132 APPPPPPPVSAPAAEAAPPASAATIAAA 159



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 50/135 (37%), Positives = 60/135 (44%), Gaps = 33/135 (24%)

Query: 461 PPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAP 520
           PPP  Q P++           P Q    L    +AA   AAAAAAAAAAAAA AAA PAP
Sbjct: 69  PPPTPQAPAAE----------PLQVD--LLPVLAAAQESAAAAAAAAAAAAAVAAAPPAP 116

Query: 521 ALAAA-------------------AAPALAAAAAPALAAAAAPAPAPAAAPA--VAAAPA 559
           A A+                    +APA  AA   + A  AA A     AP   VA AP 
Sbjct: 117 AAASTVDTAALKQPPAPPPPPPPVSAPAAEAAPPASAATIAAAAATAVVAPTSTVAVAPV 176

Query: 560 AAASAAPSHSQKPSV 574
           A+A    + S+ P +
Sbjct: 177 ASALEKKTKSKGPYI 191



 Score = 34.7 bits (78), Expect = 0.40
 Identities = 19/38 (50%), Positives = 25/38 (65%)

Query: 499 IAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAP 536
           +AAAAAAAAAAAAAA AA P    + + A  +  ++ P
Sbjct: 434 MAAAAAAAAAAAAAAVAAPPTAVGSLSGAEGVPVSSQP 471



 Score = 34.3 bits (77), Expect = 0.53
 Identities = 20/43 (46%), Positives = 24/43 (55%)

Query: 528 PALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQ 570
           P  AAAAA A AAAAA A  P A  +++ A     S+ P  SQ
Sbjct: 433 PMAAAAAAAAAAAAAAVAAPPTAVGSLSGAEGVPVSSQPLPSQ 475



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 20/49 (40%), Positives = 27/49 (55%), Gaps = 5/49 (10%)

Query: 499 IAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPA 547
           +   AAAAAAAAAAAAAA  AP  A       + + A  +  ++ P P+
Sbjct: 431 VCPMAAAAAAAAAAAAAAVAAPPTAVG-----SLSGAEGVPVSSQPLPS 474



 Score = 30.8 bits (68), Expect = 5.8
 Identities = 18/40 (45%), Positives = 24/40 (60%)

Query: 498 AIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPA 537
           A AAAAAAAAAAAA AA      +L+ A    +++   P+
Sbjct: 435 AAAAAAAAAAAAAAVAAPPTAVGSLSGAEGVPVSSQPLPS 474



 Score = 30.0 bits (66), Expect = 9.9
 Identities = 16/26 (61%), Positives = 18/26 (69%)

Query: 492 PFSAAAAIAAAAAAAAAAAAAAAAAA 517
           P +AAAA AAAAAAAA AA   A  +
Sbjct: 433 PMAAAAAAAAAAAAAAVAAPPTAVGS 458



 Score = 30.0 bits (66), Expect = 9.9
 Identities = 17/40 (42%), Positives = 21/40 (52%)

Query: 510 AAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPA 549
           AAAAAAAA A A A AA P    + + A     +  P P+
Sbjct: 435 AAAAAAAAAAAAAAVAAPPTAVGSLSGAEGVPVSSQPLPS 474


>gi|117938759 GNAS complex locus XLas [Homo sapiens]
          Length = 1037

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 66/215 (30%), Positives = 80/215 (37%), Gaps = 25/215 (11%)

Query: 386 PDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSS----------SGPASVSQL 435
           PD      RP  E +A      A  +   KV  PG  S ++          + PA+ +  
Sbjct: 343 PDKRERAERPPVEEEAAEMEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADP 402

Query: 436 SSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSA 495
            S  TPE PD        SG     P             +      P    +P       
Sbjct: 403 DSGATPEDPD--------SGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAP------D 448

Query: 496 AAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVA 555
           A A   + AA  A A   A AAP    A AAA   AA  APA   A AP  APAA+   A
Sbjct: 449 APADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPT-APAASATRA 507

Query: 556 AAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPT 590
           A    AASAAP+   +  + L   S    AA PPT
Sbjct: 508 AQVRRAASAAPASGARRKIHLRPPSPEIQAADPPT 542



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 82/377 (21%), Positives = 129/377 (34%), Gaps = 41/377 (10%)

Query: 441 PEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIA 500
           PE+P  +   +    +G   PPP   +P        G+  PP      + +    ++  A
Sbjct: 199 PEEPQALR-PAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQ-VDGSSQFA 256

Query: 501 AAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAP-AVAAAPA 559
           A AA++A     AA A P     A  +P+  A   P+    ++P    +  P  + +APA
Sbjct: 257 AVAASSAVRLTPAANAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPA 316

Query: 560 AAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGL--KAINVEGPV 617
                          P+   S P     PP K +  AP  + R     +  +A  +EG  
Sbjct: 317 GV----------DDTPVNMDSPPIALDGPPIK-VSGAPDKRERAERPPVEEEAAEMEGAA 365

Query: 618 QGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARPGAVQASSPAPLQFFLNT 677
             A+        V +PG G+PA AG + +D  +   P   A P +              T
Sbjct: 366 DAAEG-----GKVPSPGYGSPA-AGAASADTAARAAPAAPADPDSGA------------T 407

Query: 678 PEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSL--QQLQQPTAAHPPQPG-----PQGSAL 730
           PE     T    P   A    P   +             P A   P  G     P     
Sbjct: 408 PEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDA 467

Query: 731 GLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQLPSVLRQQQPQ 790
           G + +  A PA    +       +     P     S   +AQV +     P+   +++  
Sbjct: 468 GAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIH 527

Query: 791 PQPPKLQLQPQWQPKPR 807
            +PP  ++Q    P PR
Sbjct: 528 LRPPSPEIQAADPPTPR 544



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 75/259 (28%), Positives = 95/259 (36%), Gaps = 54/259 (20%)

Query: 453 VSGKGEKH-----PPPRTQLPSSSGKISS--GNSFPPQQAGSPLKRPFSAAAAIAAAAAA 505
           VSG  +K      PP   +     G   +  G   P    GSP     SA  A  AA AA
Sbjct: 339 VSGAPDKRERAERPPVEEEAAEMEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAA 398

Query: 506 AA----------------------AAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAA 543
            A                       A AA   +  APA A A   + AA  APA   + A
Sbjct: 399 PADPDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPA-APADPDSGAAPDAPADPDSGA 457

Query: 544 PAPAPA-----AAPAVAAAPAAA-------ASAAPSHSQKPSVPLIQASRPCPAAQPPTK 591
              APA     AAP   AAPAAA       A AAP  +  P+ P   A+R    A    +
Sbjct: 458 APDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPD-AGAPTAPAASATR----AAQVRR 512

Query: 592 FIKIAPA------IQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISG 645
               APA      I LR  S  ++A +   P +  +A     K   + G       G++ 
Sbjct: 513 AASAAPASGARRKIHLRPPSPEIQAADPPTP-RPTRASAWRGKSESSRGRRVYYDEGVAS 571

Query: 646 SDLQSSGGPLPDARPGAVQ 664
           SD  SSG    D   G ++
Sbjct: 572 SDDDSSGDESDDGTSGCLR 590



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 52/197 (26%), Positives = 71/197 (36%), Gaps = 21/197 (10%)

Query: 544 PAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPP----TKFIKIAPAI 599
           P   P  AP  AA  A  + A    ++ P    I       A  PP      F  + PA 
Sbjct: 26  PEQPPLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQVLNPAF 85

Query: 600 QLRTGSTGLKAINVEG--PVQGAQ-ALGSSFKPVQAPGSGAPAPAGIS--GSDLQSSGGP 654
           +   G+ G  +   E   P +  Q +LG  +  ++ PG  +   AG+   G  L   G  
Sbjct: 86  R-EAGAHGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGA- 143

Query: 655 LPDARPGAVQASSP----APLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQ 710
              ARPG    S P     P +F      G   L LLQVP        P       V   
Sbjct: 144 FSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQL-LLQVPD-----LAPGGPGAAGVPGA 197

Query: 711 QLQQPTAAHPPQPGPQG 727
             ++P A  P + G +G
Sbjct: 198 PPEEPQALRPAKAGSRG 214


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.128    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,852,425
Number of Sequences: 37866
Number of extensions: 2600309
Number of successful extensions: 57563
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 938
Number of HSP's successfully gapped in prelim test: 1568
Number of HSP's that attempted gapping in prelim test: 18277
Number of HSP's gapped (non-prelim): 16234
length of query: 887
length of database: 18,247,518
effective HSP length: 111
effective length of query: 776
effective length of database: 14,044,392
effective search space: 10898448192
effective search space used: 10898448192
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.