Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 209977117
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|209977117 unc-5 homolog D [Homo sapiens]
(953 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209977117 unc-5 homolog D [Homo sapiens] 1977 0.0
gi|32261318 unc-5 homolog B [Homo sapiens] 1004 0.0
gi|16933525 unc5C [Homo sapiens] 930 0.0
gi|62243567 netrin receptor Unc5h1 [Homo sapiens] 645 0.0
gi|118572606 hemicentin 1 [Homo sapiens] 134 5e-31
gi|40317628 thrombospondin 2 precursor [Homo sapiens] 110 5e-24
gi|147904700 semaphorin 5A [Homo sapiens] 110 6e-24
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 106 9e-23
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [... 102 1e-21
gi|40317626 thrombospondin 1 precursor [Homo sapiens] 100 1e-20
gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens] 98 3e-20
gi|224994173 roundabout 1 isoform d [Homo sapiens] 96 1e-19
gi|224994171 roundabout 1 isoform c [Homo sapiens] 96 1e-19
gi|19743806 roundabout 1 isoform b [Homo sapiens] 96 1e-19
gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo ... 96 1e-19
gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo ... 96 1e-19
gi|4506569 roundabout 1 isoform a [Homo sapiens] 96 1e-19
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 96 2e-19
gi|61888896 roundabout, axon guidance receptor, homolog 2 isofor... 96 2e-19
gi|27734865 unc-5 homolog C-like [Homo sapiens] 95 3e-19
gi|4505737 complement factor properdin precursor [Homo sapiens] 94 5e-19
gi|223671861 complement factor properdin precursor [Homo sapiens] 94 5e-19
gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo ... 87 1e-16
gi|134031945 SCO-spondin [Homo sapiens] 86 2e-16
gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens] 84 5e-16
gi|17511435 roundabout homolog 4, magic roundabout [Homo sapiens] 70 1e-11
gi|116875765 tight junction protein 1 isoform b [Homo sapiens] 65 2e-10
gi|116875767 tight junction protein 1 isoform a [Homo sapiens] 65 2e-10
gi|110735441 ADAM metallopeptidase with thrombospondin type 1 mo... 65 3e-10
gi|189242612 complement component 6 precursor [Homo sapiens] 65 4e-10
>gi|209977117 unc-5 homolog D [Homo sapiens]
Length = 953
Score = 1977 bits (5122), Expect = 0.0
Identities = 953/953 (100%), Positives = 953/953 (100%)
Query: 1 MGRAAATAGGGGGARRWLPWLGLCFWAAGTAAARGTDNGEALPESIPSAPGTLPHFIEEP 60
MGRAAATAGGGGGARRWLPWLGLCFWAAGTAAARGTDNGEALPESIPSAPGTLPHFIEEP
Sbjct: 1 MGRAAATAGGGGGARRWLPWLGLCFWAAGTAAARGTDNGEALPESIPSAPGTLPHFIEEP 60
Query: 61 DDAYIIKSNPIALRCKARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVREVFINVTR 120
DDAYIIKSNPIALRCKARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVREVFINVTR
Sbjct: 61 DDAYIIKSNPIALRCKARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVREVFINVTR 120
Query: 121 QQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHC 180
QQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHC
Sbjct: 121 QQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHC 180
Query: 181 RPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVAKR 240
RPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVAKR
Sbjct: 181 RPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVAKR 240
Query: 241 RSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKIT 300
RSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKIT
Sbjct: 241 RSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKIT 300
Query: 301 CTSLCPVDGSWEVWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCI 360
CTSLCPVDGSWEVWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCI
Sbjct: 301 CTSLCPVDGSWEVWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCI 360
Query: 361 LDKKPLHEIKPQSIENASDIALYSGLGAAVVAVAVLVIGVTLYRRSQSDYGVDVIDSSAL 420
LDKKPLHEIKPQSIENASDIALYSGLGAAVVAVAVLVIGVTLYRRSQSDYGVDVIDSSAL
Sbjct: 361 LDKKPLHEIKPQSIENASDIALYSGLGAAVVAVAVLVIGVTLYRRSQSDYGVDVIDSSAL 420
Query: 421 TGGFQTFNFKTVRQGNSLLLNSAMQPDLTVSRTYSGPICLQDPLDKELMTESSLFNPLSD 480
TGGFQTFNFKTVRQGNSLLLNSAMQPDLTVSRTYSGPICLQDPLDKELMTESSLFNPLSD
Sbjct: 421 TGGFQTFNFKTVRQGNSLLLNSAMQPDLTVSRTYSGPICLQDPLDKELMTESSLFNPLSD 480
Query: 481 IKVKVQSSFMVSLGVSERAEYHGKNHSRTFPHGNNHSFSTMHPRNKMPYIQNLSSLPTRT 540
IKVKVQSSFMVSLGVSERAEYHGKNHSRTFPHGNNHSFSTMHPRNKMPYIQNLSSLPTRT
Sbjct: 481 IKVKVQSSFMVSLGVSERAEYHGKNHSRTFPHGNNHSFSTMHPRNKMPYIQNLSSLPTRT 540
Query: 541 ELRTTGVFGHLGGRLVMPNTGVSLLIPHGAIPEENSWEIYMSINQGEPSLQSDGSEVLLS 600
ELRTTGVFGHLGGRLVMPNTGVSLLIPHGAIPEENSWEIYMSINQGEPSLQSDGSEVLLS
Sbjct: 541 ELRTTGVFGHLGGRLVMPNTGVSLLIPHGAIPEENSWEIYMSINQGEPSLQSDGSEVLLS 600
Query: 601 PEVTCGPPDMIVTTPFALTIPHCADVSSEHWNIHLKKRTQQGKWEEVMSVEDESTSCYCL 660
PEVTCGPPDMIVTTPFALTIPHCADVSSEHWNIHLKKRTQQGKWEEVMSVEDESTSCYCL
Sbjct: 601 PEVTCGPPDMIVTTPFALTIPHCADVSSEHWNIHLKKRTQQGKWEEVMSVEDESTSCYCL 660
Query: 661 LDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAF 720
LDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAF
Sbjct: 661 LDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAF 720
Query: 721 QEVVSDERHQGGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWC 780
QEVVSDERHQGGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWC
Sbjct: 721 QEVVSDERHQGGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWC 780
Query: 781 SNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQVQTSILESERETITFFAQEDS 840
SNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQVQTSILESERETITFFAQEDS
Sbjct: 781 SNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQVQTSILESERETITFFAQEDS 840
Query: 841 TFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAV 900
TFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAV
Sbjct: 841 TFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAV 900
Query: 901 ILNLWEARHQHDGDLDSLACALEEIGRTHTKLSNISESQLDEADFNYSRQNGL 953
ILNLWEARHQHDGDLDSLACALEEIGRTHTKLSNISESQLDEADFNYSRQNGL
Sbjct: 901 ILNLWEARHQHDGDLDSLACALEEIGRTHTKLSNISESQLDEADFNYSRQNGL 953
>gi|32261318 unc-5 homolog B [Homo sapiens]
Length = 945
Score = 1004 bits (2595), Expect = 0.0
Identities = 505/933 (54%), Positives = 660/933 (70%), Gaps = 14/933 (1%)
Query: 9 GGGGGARRWLPWLGLCFWAAGTAAARGTDNG-EALPESIPSAPGT-LPHFIEEPDDAYII 66
G GAR L L W + A GTD+G E LP+S PSAP LP+F++EP DAYI+
Sbjct: 2 GARSGARGALLLALLLCWDPRLSQA-GTDSGSEVLPDSFPSAPAEPLPYFLQEPQDAYIV 60
Query: 67 KSNPIALRCKARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVREVFINVTRQQVEDF 126
K+ P+ LRC+A PA QI+FKCNGEWV QN+HV++E LDE++GL+VREV I V+RQQVE+
Sbjct: 61 KNKPVELRCRAFPATQIYFKCNGEWVSQNDHVTQEGLDEATGLRVREVQIEVSRQQVEEL 120
Query: 127 HGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGV 186
G EDYWCQCVAWS GT+KSR+A VRIAYLRKNF+Q+P G+EVP++ ++L CRPPEGV
Sbjct: 121 FGLEDYWCQCVAWSSAGTTKSRRAYVRIAYLRKNFDQEPLGKEVPLDHEVLLQCRPPEGV 180
Query: 187 PAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVAKRRSLSAT 246
P AEVEWLKNE+ ID QD N DHNLIIRQARLSD+ NYTC+A NIVAKRRS +AT
Sbjct: 181 PVAEVEWLKNEDVIDPTQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTAT 240
Query: 247 VVVYVNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSLCP 306
V+VYVNGGWSSW EWS C+ RCGRGWQKR+RTCTNPAPLNGGAFCEG + QK CT++CP
Sbjct: 241 VIVYVNGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTICP 300
Query: 307 VDGSWEVWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILDKKPL 366
VDG+W WS+WS CS EC H R REC APPP+NGG+ C G +S+NCTDGLC+ +KK L
Sbjct: 301 VDGAWTEWSKWSACSTECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCMQNKKTL 360
Query: 367 HEIKPQSIENASDIALYSGLGAAV-VAVAVLV-IGVTLYRRSQSDYGVDVIDSS-ALTGG 423
+ +E + D ALY+GL A+ V VA+L+ +GV +YRR+ D+ D+ DSS ALTGG
Sbjct: 361 SDPNSHLLEASGDAALYAGLVVAIFVVVAILMAVGVVVYRRNCRDFDTDITDSSAALTGG 420
Query: 424 FQTFNFKTVRQGNSLLLNSAMQPDLTVSR-TYSGPI-CLQDPLDKELMTESSLFNPLSDI 481
F NFKT R N LL+ ++ PDLT S Y GP+ LQD DK MT S L +PL +
Sbjct: 421 FHPVNFKTARPSNPQLLHPSVPPDLTASAGIYRGPVYALQDSTDKIPMTNSPLLDPLPSL 480
Query: 482 KVKVQSSFMVSL--GVSERAEYHGKNHSRTFPHGNNHSFSTMHPRNKMPYIQNLSSLPTR 539
KVKV SS G+++ A+ G T+P +H R+ Q L LP
Sbjct: 481 KVKVYSSSTTGSGPGLADGADLLGVLPPGTYPSDFARDTHFLHLRSASLGSQQLLGLPRD 540
Query: 540 TELRTTGVFGHLGGRLVMPNTGVSLLIPHGAIPEENSWEIYMSINQGEPSLQ-SDGSEVL 598
+G FG LGGRL +P TGVSLL+P+GAIP+ +E+Y+ IN+ E +L S+G++ +
Sbjct: 541 PGSSVSGTFGCLGGRLSIPGTGVSLLVPNGAIPQGKFYEMYLLINKAESTLPLSEGTQTV 600
Query: 599 LSPEVTCGPPDMIVTTPFALTIPHCADVSSEHWNIHLKKRTQQGKWEEVMSVEDE--STS 656
LSP VTCGP +++ P LT+PHCA+VS+ W LK + QG WEEV+++++E +T
Sbjct: 601 LSPSVTCGPTGLLLCRPVILTMPHCAEVSARDWIFQLKTQAHQGHWEEVVTLDEETLNTP 660
Query: 657 CYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNT 716
CYC L+P ACH+LLD GTY TGE + AVK+L++AVF C SL+Y+LRVYC+++T
Sbjct: 661 CYCQLEPRACHILLDQLGTYVFTGESYSRSAVKRLQLAVFAPALCTSLEYSLRVYCLEDT 720
Query: 717 PCAFQEVVSDERHQGGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFS 776
P A +EV+ ER GG L+EEPK L FK + +L++S+ D+P WR K QE+PF
Sbjct: 721 PVALKEVLELERTLGGYLVEEPKPLMFKDSYHNLRLSLHDLPHAHWRSKLLAKYQEIPFY 780
Query: 777 RVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQVQTSILESERETI-TFF 835
+W +++ LHC F+LER++ +T+L+CKIC+RQ++G QI Q+ T++ E+ ++ T
Sbjct: 781 HIWSGSQKALHCTFTLERHSLASTELTCKICVRQVEGEGQIFQLHTTLAETPAGSLDTLC 840
Query: 836 AQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQS 895
+ ST Q GP AFKIP SIRQ+IC + D PN++G DW+MLAQK S++R L+YFAT++
Sbjct: 841 SAPGSTVTTQLGPYAFKIPLSIRQKICNSLDAPNSRGNDWRMLAQKLSMDRYLNYFATKA 900
Query: 896 SPSAVILNLWEARHQHDGDLDSLACALEEIGRT 928
SP+ VIL+LWEA Q DGDL+SLA ALEE+G++
Sbjct: 901 SPTGVILDLWEALQQDDGDLNSLASALEEMGKS 933
>gi|16933525 unc5C [Homo sapiens]
Length = 931
Score = 930 bits (2404), Expect = 0.0
Identities = 470/938 (50%), Positives = 630/938 (67%), Gaps = 48/938 (5%)
Query: 18 LPWLGLCFWAAGTAAARGTDNGEALPESIPS-APGTLPHFIEEPDDAYIIKSNPIALRCK 76
LP L L + +AA+ D LPE+ PS P LPHF+ EP++AYI+K+ P+ L CK
Sbjct: 25 LPALALLSASGTGSAAQDDDFFHELPETFPSDPPEPLPHFLIEPEEAYIVKNKPVNLYCK 84
Query: 77 ARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVREVFINVTRQQVEDFHGPEDYWCQC 136
A PA QI+FKCN EWVHQ +H+ +E +DE+SGL VREV I ++RQQVE+ GPEDYWCQC
Sbjct: 85 ASPATQIYFKCNSEWVHQKDHIVDERVDETSGLIVREVSIEISRQQVEELFGPEDYWCQC 144
Query: 137 VAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEWLKN 196
VAWS GT+KSRKA VRIAYLRK FEQ+P G+EV +E ++L CRPPEG+P AEVEWLKN
Sbjct: 145 VAWSSAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKN 204
Query: 197 EEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVAKRRSLSATVVVYVNGGWS 256
E+ ID +D N DHNLII+QARLSD+ NYTC+A NIVAKR+S +ATV+VYVNGGWS
Sbjct: 205 EDIIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWS 264
Query: 257 SWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSLCPVDGSWEVWSE 316
+WTEWS CN RCGRG+QKR+RTCTNPAPLNGGAFCEG SVQKI CT+LCPVDG W WS+
Sbjct: 265 TWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTPWSK 324
Query: 317 WSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILDKKPLHEIKPQSIEN 376
WS C EC H R RECTAP P+NGGK C+GL +S+NCTDGLC+ Q+ +
Sbjct: 325 WSTCGTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCM-----------QTAPD 373
Query: 377 ASDIALYSGLGAAVVAVAVL--VIGVTLYRRSQSDYGVDVIDSSALTGGFQTFNFKTVRQ 434
+ D+ALY G+ AV+ + V+ + +YR++ D+ D+IDSSAL GGFQ N K RQ
Sbjct: 374 SDDVALYVGIVIAVIVCLAISVVVALFVYRKNHRDFESDIIDSSALNGGFQPVNIKAARQ 433
Query: 435 GNSLLLNSAMQPDLT-VSRTYSGPI-CLQDPLDKELMTESSLFNPLSDIKVKVQSSFMVS 492
LL A+ PDLT + Y GP+ L D DK MT S + +PL ++K+KV ++
Sbjct: 434 --DLL---AVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNTSGAV 488
Query: 493 LGVSERAEYHGKNHSRTFPHGNNHSFSTMHPRNKMPYIQNLS-SLPTRTELRTT------ 545
+ +E+ K + P+ ++N + SL ++ R T
Sbjct: 489 TPQDDLSEFTSK----------------LSPQMTQSLLENEALSLKNQSLARQTDPSCTA 532
Query: 546 -GVFGHLGGRLVMPNTGVSLLIPHGAIPEENSWEIYMSINQGEPSL-QSDGSEVLLSPEV 603
G F LGG L++PN+GVSLLIP GAIP+ +E+Y+++++ E D S+ LL+P V
Sbjct: 533 FGSFNSLGGHLIVPNSGVSLLIPAGAIPQGRVYEMYVTVHRKETMRPPMDDSQTLLTPVV 592
Query: 604 TCGPPDMIVTTPFALTIPHCADVSSEHWNIHLKKRTQQGKWEEVMSVEDE--STSCYCLL 661
+CGPP ++T P LT+ HCAD ++E W I LK + QG+WE+V+ V +E +T CY L
Sbjct: 593 SCGPPGALLTRPVVLTMHHCADPNTEDWKILLKNQAAQGQWEDVVVVGEENFTTPCYIKL 652
Query: 662 DPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQ 721
D ACH+L ++ TYAL G T A K+LK+A+FG + C+SL+Y++RVYC+D+T A +
Sbjct: 653 DAEACHILTENLSTYALVGHSTTKAAAKRLKLAIFGPLCCSSLEYSIRVYCLDDTQDALK 712
Query: 722 EVVSDERHQGGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCS 781
E++ ER GGQLLEEPK LHFKG+T +L++S+ DI LW+ K QE+PF VW
Sbjct: 713 EILHLERQTGGQLLEEPKALHFKGSTHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHVWSG 772
Query: 782 NRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQVQTSILESERETITFFAQEDST 841
+++ LHC F+LER++ T +L CK+C+RQ++G QI Q+ ++ E +T
Sbjct: 773 SQRNLHCTFTLERFSLNTVELVCKLCVRQVEGEGQIFQLNCTVSEEPTGIDLPLLDPANT 832
Query: 842 FPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVI 901
TGP AF IP IRQ++C++ D P +G DW+MLA K +++R L+YFAT+SSP+ VI
Sbjct: 833 ITTVTGPSAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVI 892
Query: 902 LNLWEARHQHDGDLDSLACALEEIGRTHTKLSNISESQ 939
L+LWEA++ DG+L LA LEE+GR T +S +E Q
Sbjct: 893 LDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAEGQ 930
>gi|62243567 netrin receptor Unc5h1 [Homo sapiens]
Length = 842
Score = 645 bits (1664), Expect = 0.0
Identities = 363/934 (38%), Positives = 523/934 (55%), Gaps = 111/934 (11%)
Query: 17 WLPWLG--LCFWAAGTAAARGTDNGEALPESIPSA-PGTLPHFIEEPDDAYIIKSNPIAL 73
W LG L W G+ G + +P A P LPHF+ EP+D YI+K+ P+ L
Sbjct: 8 WPALLGIVLAAWLRGS----GAQQSATVANPVPGANPDLLPHFLVEPEDVYIVKNKPVLL 63
Query: 74 RCKARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVREVFINVTRQQVEDFHGPEDYW 133
CKA PA QIFFKCNGEWV Q +HV E + D SSGL EV INV+RQQVE G E+YW
Sbjct: 64 VCKAVPATQIFFKCNGEWVRQVDHVIERSTDGSSGLPTMEVRINVSRQQVEKVFGLEEYW 123
Query: 134 CQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEW 193
CQCVAWS GT+KS+KA +RIAYLRKNFEQ+P +EV +E IVL CRPPEG+P AEVEW
Sbjct: 124 CQCVAWSSSGTTKSQKAYIRIAYLRKNFEQEPLAKEVSLEQGIVLPCRPPEGIPPAEVEW 183
Query: 194 LKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVAKRRSLSATVVVYVNG 253
L+NE + +D D N+ I + ++V ++ L+ T
Sbjct: 184 LRNE--------DLVDPSLDPNVYITREH------------SLVVRQARLADTA------ 217
Query: 254 GWSSWTEWSACNVRC-GRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSLCPVDGSWE 312
N C + R R+ + + VDGSW
Sbjct: 218 -----------NYTCVAKNIVARRRSAS--------------------AAVIVYVDGSWS 246
Query: 313 VWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILDKKPLHEIKPQ 372
WS+WS C +C H R REC+ P PRNGG+ C+G ++ NCT LC+
Sbjct: 247 PWSKWSACGLDCTHWRSRECSDPAPRNGGEECQGTDLDTRNCTSDLCV-----------H 295
Query: 373 SIENASDIALYSGL-GAAVVAVAVLVIGVTLYRRSQSDYGVDVIDSSALTGGFQTFNFKT 431
+ D+ALY GL AV V +L++ + +Y R + DV DSS LT GFQ + K
Sbjct: 296 TASGPEDVALYVGLIAVAVCLVLLLLVLILVYCRKKEGLDSDVADSSILTSGFQPVSIKP 355
Query: 432 VRQGNSLLLNSAMQPDL-TVSRTYSGPICLQD--PLDKELMTESSLFNPLSDIKVKVQSS 488
+ N LL +QPDL T + TY G +C + P K +T L +PL + + S
Sbjct: 356 SKADNPHLL--TIQPDLSTTTTTYQGSLCPRQDGPSPKFQLTNGHLLSPLGGGRHTLHHS 413
Query: 489 FMVSLGVSERAEYHGKNHSRTFPHGNNHSFSTMHPRNKMPYIQNLSSLPTRTELRTTGVF 548
S + +N+ R+ P G T T G F
Sbjct: 414 SPTSEAEEFVSRLSTQNYFRSLPRG--------------------------TSNMTYGTF 447
Query: 549 GHLGGRLVMPNTGVSLLIPHGAIPEENSWEIYMSINQGEP-SLQSDGSEVLLSPEVTCGP 607
LGGRL++PNTG+SLLIP AIP +EIY+++++ E L G + LLSP V+CGP
Sbjct: 448 NFLGGRLMIPNTGISLLIPPDAIPRGKIYEIYLTLHKPEDVRLPLAGCQTLLSPIVSCGP 507
Query: 608 PDMIVTTPFALTIPHCADVSSEHWNIHLKKRTQQGKWEEVMSVEDESTS--CYCLLDPFA 665
P +++T P L + HC + S + W++ LKK++ +G WE+V+ + +E+ S YC L+ A
Sbjct: 508 PGVLLTRPVILAMDHCGEPSPDSWSLRLKKQSCEGSWEDVLHLGEEAPSHLYYCQLEASA 567
Query: 666 CHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVS 725
C+V + G +AL GE ++ A K+LK+ +F ++C SL+YN+RVYC+ +T A +EVV
Sbjct: 568 CYVFTEQLGRFALVGEALSVAAAKRLKLLLFAPVACTSLEYNIRVYCLHDTHDALKEVVQ 627
Query: 726 DERHQGGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQP 785
E+ GGQL++EP++LHFK + +L++S+ D+P LW+ K + QE+PF +W ++
Sbjct: 628 LEKQLGGQLIQEPRVLHFKDSYHNLRLSIHDVPSSLWKSKLLVSYQEIPFYHIWNGTQRY 687
Query: 786 LHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQVQTSILESERETITFFAQEDSTFPAQ 845
LHC F+LER +P+T+ L+CK+ + Q++G Q + +I + R + ++ PA
Sbjct: 688 LHCTFTLERVSPSTSDLACKLWVWQVEGDGQSFSINFNITKDTRFAELLALESEAGVPAL 747
Query: 846 TGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLW 905
GP AFKIP+ IRQ+I ++ D P +G DW+ LAQK ++ +LS+FA++ SP+A+ILNLW
Sbjct: 748 VGPSAFKIPFLIRQKIISSLDPPCRRGADWRTLAQKLHLDSHLSFFASKPSPTAMILNLW 807
Query: 906 EARHQHDGDLDSLACALEEIGRTHTKLSNISESQ 939
EARH +G+L LA A+ +G+ L +SE++
Sbjct: 808 EARHFPNGNLSQLAAAVAGLGQPDAGLFTVSEAE 841
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 134 bits (336), Expect = 5e-31
Identities = 68/190 (35%), Positives = 102/190 (53%), Gaps = 8/190 (4%)
Query: 174 GMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMA 233
G I+L+C+ G P + W + I D+ ++ ++++L I A+ D+ + C+A
Sbjct: 4455 GKIILNCQAT-GEPQPTITWSRQGHSIS--WDDRVNVLSNNSLYIADAQKEDTSEFECVA 4511
Query: 234 ANIVAKRRSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEG 293
N++ + V+V V+GG+S W+ W AC+V CG+G QKRSR C P P NGG C+G
Sbjct: 4512 RNLMGSVL-VRVPVIVQVHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQG 4570
Query: 294 MSVQKITCTSL-CPVDGSWEVWSEWSVCSPEC---EHLRIRECTAPPPRNGGKFCEGLSQ 349
++ C + CPVDGSW WS W C+ C R R C P ++GG+ CEG +
Sbjct: 4571 SDLEMRNCQNKPCPVDGSWSEWSLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAV 4630
Query: 350 ESENCTDGLC 359
E C C
Sbjct: 4631 EIIMCNIRPC 4640
Score = 114 bits (285), Expect = 4e-25
Identities = 49/116 (42%), Positives = 66/116 (56%), Gaps = 4/116 (3%)
Query: 251 VNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTS-LCPVDG 309
++G W++W WSAC+V CG G ++R+R C++P P GG CEG VQ C S CP G
Sbjct: 4699 IHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTHG 4758
Query: 310 SWEVWSEWSVCSPEC---EHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILD 362
+W WS W CS C + R R C PPP NGG+ C G + + C +C +D
Sbjct: 4759 NWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCPVD 4814
Score = 111 bits (277), Expect = 4e-24
Identities = 46/113 (40%), Positives = 61/113 (53%), Gaps = 4/113 (3%)
Query: 251 VNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSL-CPVDG 309
V+G WS+W W C+ CG+G Q R+R C NP P GG++C+G Q C CP+ G
Sbjct: 4642 VHGAWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCPIHG 4701
Query: 310 SWEVWSEWSVCSPEC---EHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLC 359
W W+ WS CS C R R C+ P P+ GG+ CEG +S+ C C
Sbjct: 4702 KWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPC 4754
Score = 110 bits (276), Expect = 5e-24
Identities = 49/118 (41%), Positives = 63/118 (53%), Gaps = 4/118 (3%)
Query: 251 VNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSL-CPVDG 309
V+G WS W+ W C CGRG Q R+RTC NP+ +GG CEG +V+ I C CPV G
Sbjct: 4585 VDGSWSEWSLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVHG 4644
Query: 310 SWEVWSEWSVCSPEC---EHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILDKK 364
+W W W CS C R R C PPP GG +C+G + + C + C + K
Sbjct: 4645 AWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCPIHGK 4702
Score = 101 bits (251), Expect = 4e-21
Identities = 48/112 (42%), Positives = 56/112 (50%), Gaps = 4/112 (3%)
Query: 252 NGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITC-TSLCPVDGS 310
+G WS W+ W C+ C G +R RTC NP P NGG C G Q C T +CPVDGS
Sbjct: 4757 HGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCPVDGS 4816
Query: 311 WEVWSEWSVCSPEC---EHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLC 359
W W WS CS C E R R C P P GG+ C G + + C C
Sbjct: 4817 WGSWHSWSQCSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQAC 4868
Score = 67.0 bits (162), Expect = 8e-11
Identities = 91/359 (25%), Positives = 126/359 (35%), Gaps = 80/359 (22%)
Query: 53 LPHFIEEPDDAYIIKSNPIALRCKAR----PAMQIFFKCNGEWVH------QNEHVSEET 102
LP F E P D + K + L CKA P + F N H +E V E
Sbjct: 4259 LPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERV 4318
Query: 103 LDESSGLKVREVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKN-- 160
E SG V C A + +G K+ + Y+++
Sbjct: 4319 SKEDSGTYV------------------------CTAENSVGFVKA----IGFVYVKEPPV 4350
Query: 161 FEQD-PQGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIR 219
F+ D P P+ G +L+C +G P ++W N + +D E I + +L I
Sbjct: 4351 FKGDYPSNWIEPLGGNAILNCEV-KGDPTPTIQW--NRKGVDIEISHRIRQLGNGSLAIY 4407
Query: 220 QARLSDSGNYTCMAANIVAK-RRSLSAT-----------VVVYVNGGWSSWTEWSACNV- 266
D+G+YTC+A N RS+S T V +N G A
Sbjct: 4408 GTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEP 4467
Query: 267 -------RCGRG--WQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSLC-----------P 306
R G W R +N + A E S + +L
Sbjct: 4468 QPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527
Query: 307 VDGSWEVWSEWSVCSPECE---HLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILD 362
V G + WS W CS C R R C P P NGGK C+G E NC + C +D
Sbjct: 4528 VHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVD 4586
Score = 58.2 bits (139), Expect = 4e-08
Identities = 24/57 (42%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 251 VNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITC-TSLCP 306
V+G W SW WS C+ CG G + R R C +P P+ GG C G + Q C CP
Sbjct: 4813 VDGSWGSWHSWSQCSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACP 4869
Score = 53.9 bits (128), Expect = 7e-07
Identities = 62/253 (24%), Positives = 107/253 (42%), Gaps = 34/253 (13%)
Query: 60 PDDAYIIKSNPIALRCKAR---PAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVREVFI 116
P+D +I ++P +L C+A PA +FK +G + N ++ L L++ +
Sbjct: 2582 PEDVTVILNSPTSLVCEAYSYPPATITWFK-DGTPLESNRNI--RILPGGRTLQI----L 2634
Query: 117 NVTRQQVEDFHGPEDYWCQCVAWSHLGTS-KSRKASVRIAYLRKNFEQ-----DPQGREV 170
N + CVA + G K + V I + + P+ ++
Sbjct: 2635 NAQEDNAGRY--------SCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKI 2686
Query: 171 PIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYT 230
+ + L C +P+A + W K+ +P+ S+ NI H L I++A++SD+G YT
Sbjct: 2687 KVNNTLTLECEA-YAIPSASLSWYKDGQPLKSDDHVNIAANG-HTLQIKEAQISDTGRYT 2744
Query: 231 CMAANIVAKRRSLSATVVVYVNGGWSSWTEWSACN-VRCGRGWQKRSRTCTNPAPLNGGA 289
C+A+NI A L V + V + W N + GR + + NP L
Sbjct: 2745 CVASNI-AGEDELDFDVNIQVPPSFQKL--WEIGNMLDTGRNGEAKDVIINNPISL---- 2797
Query: 290 FCEGMSVQKITCT 302
+CE + T T
Sbjct: 2798 YCETNAAPPPTLT 2810
Score = 50.1 bits (118), Expect = 1e-05
Identities = 52/194 (26%), Positives = 84/194 (43%), Gaps = 30/194 (15%)
Query: 53 LPHFIEEPDDAYIIK--SNPIALRCKAR--PAMQIFFKCNGEWVHQNEHVSEETLDESSG 108
+P IE P+ I++ SNP+ L C A P I + N + + ++ + L S
Sbjct: 3149 VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSK 3208
Query: 109 LKVREVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGR 168
L++ R Q D +Y C + ++ KA + +L G
Sbjct: 3209 LQI-------ARSQHSD---SGNYTC-------IASNMEGKAQ-KYYFLSIQVPPSVAGA 3250
Query: 169 EVPIEGMIVLH------CRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRAD-HNLIIRQA 221
E+P + ++L C G+P ++WLK+ +PI S + E I A+ L I A
Sbjct: 3251 EIPSDVSVLLGENVELVCNA-NGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGA 3309
Query: 222 RLSDSGNYTCMAAN 235
SD+G YTC+A N
Sbjct: 3310 LTSDTGKYTCVATN 3323
Score = 50.1 bits (118), Expect = 1e-05
Identities = 49/196 (25%), Positives = 87/196 (44%), Gaps = 24/196 (12%)
Query: 59 EPDDAYIIKSNPIALRCKARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVREVFINV 118
+P + ++I +NPI L C+A F E ++ N + S GL++
Sbjct: 3993 QPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQIS----RA 4048
Query: 119 TRQQVEDFHGPEDYWCQCVAWSHLGTSKSR-KASVRIAYLRKNFEQDPQGRE--VPIEGM 175
R+ + CVA + GT+ + K +V++ + P +E + ++
Sbjct: 4049 VREDAGTY--------MCVAQNPAGTALGKIKLNVQVPPV-----ISPHLKEYVIAVDKP 4095
Query: 176 IVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAAN 235
I L C +G+P ++ W K+ I + + + +L I + D+G+YTCMAAN
Sbjct: 4096 ITLSCE-ADGLPPPDITWHKDGRAIVESIRQRV--LSSGSLQIAFVQPGDAGHYTCMAAN 4152
Query: 236 IVAKRRSLSATVVVYV 251
VA S S + V+V
Sbjct: 4153 -VAGSSSTSTKLTVHV 4167
Score = 49.7 bits (117), Expect = 1e-05
Identities = 49/179 (27%), Positives = 79/179 (44%), Gaps = 23/179 (12%)
Query: 65 IIKSNPIALRCKAR--PAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVREV--FINVTR 120
++ +NP+ L C+AR PA + W+ VS S+GL+V + +T
Sbjct: 2023 VVVNNPVRLECEARGIPAPSL------TWLKDGSPVSSF----SNGLQVLSGGRILALTS 2072
Query: 121 QQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHC 180
Q+ D CVA + G K R +R+ Y+ N + Q V I + L C
Sbjct: 2073 AQISDTGR-----YTCVAVNAAG-EKQRDIDLRV-YVPPNIMGEEQNVSVLISQAVELLC 2125
Query: 181 RPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVAK 239
+ + +P + WLK+ P+ + +I L I A++ D+G YTC A N+ K
Sbjct: 2126 QS-DAIPPPTLTWLKDGHPLLKKPGLSISENRSV-LKIEDAQVQDTGRYTCEATNVAGK 2182
Score = 49.7 bits (117), Expect = 1e-05
Identities = 54/204 (26%), Positives = 93/204 (45%), Gaps = 25/204 (12%)
Query: 58 EEPDDAYIIKSNPIALRCKAR--PAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVREVF 115
EE ++ +I +NP+ L C A PA ++ + +G + Q + V +TL L++
Sbjct: 3533 EEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQV--QTLGGGEVLRI---- 3586
Query: 116 INVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPI--E 173
+ QVED C+A S G ++ VR+ ++ N + R++ +
Sbjct: 3587 ---STAQVEDTGR-----YTCLASSPAGDD-DKEYLVRV-HVPPNIAGTDEPRDITVLRN 3636
Query: 174 GMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMA 233
+ L C+ + VP + WL+N E + + I + + L I A L D+ NYTC+A
Sbjct: 3637 RQVTLECKS-DAVPPPVITWLRNGERLQATPRVRILSGGRY-LQINNADLGDTANYTCVA 3694
Query: 234 ANIVAKRRS---LSATVVVYVNGG 254
+NI K L+ V + GG
Sbjct: 3695 SNIAGKTTREFILTVNVPPNIKGG 3718
Score = 47.4 bits (111), Expect = 6e-05
Identities = 51/192 (26%), Positives = 76/192 (39%), Gaps = 22/192 (11%)
Query: 65 IIKSNPIALRCKA--RPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVREVFINVTRQQ 122
++ SNP+ L CKA P I W N +S T S R I++ Q
Sbjct: 1932 VLVSNPVQLECKAAGNPVPVI------TWYKDNRLLSGST---SMTFLNRGQIIDIESAQ 1982
Query: 123 VEDFHGPEDYWCQCVAWSHLG-TSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCR 181
+ D +CVA + G T V +A + V + + L C
Sbjct: 1983 ISDAG-----IYKCVAINSAGATELFYSLQVHVA---PSISGSNNMVAVVVNNPVRLECE 2034
Query: 182 PPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVA-KR 240
G+PA + WLK+ P+ S + L + A++SD+G YTC+A N K+
Sbjct: 2035 A-RGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQ 2093
Query: 241 RSLSATVVVYVN 252
R + V V N
Sbjct: 2094 RDIDLRVYVPPN 2105
Score = 47.0 bits (110), Expect = 8e-05
Identities = 31/81 (38%), Positives = 45/81 (55%), Gaps = 4/81 (4%)
Query: 172 IEGM-IVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYT 230
IEG + L C G P E W+KN + Q+ I R+D +L I + +L D G YT
Sbjct: 902 IEGQQLTLPCTLLAGNPIPERRWIKNSAML--LQNPYITVRSDGSLHIERVQLQDGGEYT 959
Query: 231 CMAANIVAKRRSLSATVVVYV 251
C+A+N VA + + +VVV+V
Sbjct: 960 CVASN-VAGTNNKTTSVVVHV 979
Score = 47.0 bits (110), Expect = 8e-05
Identities = 49/198 (24%), Positives = 91/198 (45%), Gaps = 29/198 (14%)
Query: 50 PGTLPHFIEEPDDAYIIKSNPIALRCKAR--PAMQIFFKCNGEWVHQNEHVSEETLDESS 107
P H E + + ++L C++ P I + NG + ++ HV E L +
Sbjct: 3056 PSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHV--EILADGQ 3113
Query: 108 GLKVREVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQG 167
L +++ ++ T Q Y C+ + ++ + + + Y+ + E P+
Sbjct: 3114 MLHIKKAEVSDTGQ----------YVCRAI---NVAGRDDKNFHLNV-YVPPSIE-GPE- 3157
Query: 168 REVPIEGM---IVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTR---ADHNLIIRQA 221
REV +E + + L C G+P + WLKN + I E ++++ R L I ++
Sbjct: 3158 REVIVETISNPVTLTC-DATGIPPPTIAWLKNHKRI--ENSDSLEVRILSGGSKLQIARS 3214
Query: 222 RLSDSGNYTCMAANIVAK 239
+ SDSGNYTC+A+N+ K
Sbjct: 3215 QHSDSGNYTCIASNMEGK 3232
Score = 46.2 bits (108), Expect = 1e-04
Identities = 48/175 (27%), Positives = 68/175 (38%), Gaps = 23/175 (13%)
Query: 136 CVAWSHLGTSKSRKASVRIAYLRKNFEQDP-------QGREVPIEGMIVLHCRPPEGVPA 188
CVA + G++K Y N P + V + I L C G P
Sbjct: 2943 CVAENTAGSAKK--------YFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEV-SGFPP 2993
Query: 189 AEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVAK-RRSLSATV 247
++ WLKNE+PI + I L I +A++SD G YTC+A N + ++ S TV
Sbjct: 2994 PDLSWLKNEQPIKLNTNTLI-VPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052
Query: 248 VVYVNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPL-----NGGAFCEGMSVQ 297
V + S NVR G + P P+ NG E V+
Sbjct: 3053 YVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVE 3107
Score = 43.5 bits (101), Expect = 0.001
Identities = 42/195 (21%), Positives = 78/195 (40%), Gaps = 19/195 (9%)
Query: 52 TLPHFIEEPDDAYIIKSNPIALRCKAR--PAMQIFFKCNGEWVHQNEHVSEETLDESSGL 109
T+ + P + + + I+L C+ + P + + +G + + + V E LDE L
Sbjct: 2291 TITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGV--EILDEGHIL 2348
Query: 110 KVREVFINVTRQQVEDFHGPEDYWCQCVAWSHLG-TSKSRKASVRIAYLRKNFEQDPQGR 168
+++ + ++ T + V CVA + G T K SV + P+
Sbjct: 2349 QLKNIHVSDTGRYV------------CVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENI 2396
Query: 169 EVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGN 228
V + + L C G+P + W K+ P+ I L + Q + D+G
Sbjct: 2397 SVVEKNSVSLTCEA-SGIPLPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAGQ 2454
Query: 229 YTCMAANIVAKRRSL 243
YTC+ N + R +
Sbjct: 2455 YTCVVRNAAGEERKI 2469
Score = 42.7 bits (99), Expect = 0.002
Identities = 47/197 (23%), Positives = 75/197 (38%), Gaps = 25/197 (12%)
Query: 47 PSAPGTLPHFIEEPDDAYIIKSNPIALRCK--ARPAMQIFFKCNGEWVHQNEHVSEETLD 104
P+ GT +EP D ++++ + L CK A P I + NGE + V L
Sbjct: 3620 PNIAGT-----DEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRV--RILS 3672
Query: 105 ESSGLKVREVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQD 164
L++ + T CVA + G K+ + + + N +
Sbjct: 3673 GGRYLQINNADLGDTANYT------------CVASNIAG--KTTREFILTVNVPPNIKGG 3718
Query: 165 PQGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLS 224
PQ + + VL C EGVP + W K+ + + L I+ A ++
Sbjct: 3719 PQSLVILLNKSTVLECIA-EGVPTPRITWRKDGAVLAGNH-ARYSILENGFLHIQSAHVT 3776
Query: 225 DSGNYTCMAANIVAKRR 241
D+G Y CMA N R
Sbjct: 3777 DTGRYLCMATNAAGTDR 3793
Score = 40.4 bits (93), Expect = 0.008
Identities = 17/51 (33%), Positives = 29/51 (56%)
Query: 185 GVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAAN 235
G+P + WLK+++P+++ Q + L I + L D+G YTC+A N
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATN 1902
Score = 40.0 bits (92), Expect = 0.010
Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Query: 170 VPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNY 229
V I +I L C G+P + W K+ +PI S + + L I +A++SDS Y
Sbjct: 1559 VLINSLIKLECET-RGLPMPAITWYKDGQPIMSSSQALYIDKGQY-LHIPRAQVSDSATY 1616
Query: 230 TCMAANIVAKRRSLSATVVVYV 251
TC AN VA S V VYV
Sbjct: 1617 TCHVAN-VAGTAEKSFHVDVYV 1637
Score = 39.7 bits (91), Expect = 0.014
Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 8/75 (10%)
Query: 184 EGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIR--QARLSDSGNYTCMAAN---IVA 238
+G PA + WL++ +P+ + + T H ++++ +A DSG YTC+A+N V+
Sbjct: 3460 DGTPAPSMAWLRDGQPLGLDAHLTVST---HGMVLQLLKAETEDSGKYTCIASNEAGEVS 3516
Query: 239 KRRSLSATVVVYVNG 253
K L ++NG
Sbjct: 3517 KHFILKVLEPPHING 3531
Score = 38.9 bits (89), Expect = 0.023
Identities = 30/102 (29%), Positives = 44/102 (43%), Gaps = 3/102 (2%)
Query: 136 CVAWSHLGTSKSR-KASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEWL 194
CVA + GT+K V I N P V I L C +G+P V W+
Sbjct: 2269 CVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEV-QGIPPPTVTWM 2327
Query: 195 KNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANI 236
K+ P+ + I H L ++ +SD+G Y C+A N+
Sbjct: 2328 KDGHPLIKAKGVEILDEG-HILQLKNIHVSDTGRYVCVAVNV 2368
Score = 38.5 bits (88), Expect = 0.030
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 170 VPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNY 229
V + ++ L C G P + WLK+ + ID I L+I QA++S++G Y
Sbjct: 1746 VMVNNLLELDCHVT-GSPPPTIMWLKDGQLIDERDGFKILLNG-RKLVIAQAQVSNTGLY 1803
Query: 230 TCMAAN 235
CMAAN
Sbjct: 1804 RCMAAN 1809
Score = 37.4 bits (85), Expect = 0.067
Identities = 31/127 (24%), Positives = 57/127 (44%), Gaps = 8/127 (6%)
Query: 115 FINVTRQQVEDFHGPEDYWCQCVAWSHLGTS-KSRKASVRIAYLRKNFEQDPQGREVPIE 173
++++ R QV D Y C + GT+ KS V + + + P ++V I
Sbjct: 1602 YLHIPRAQVSD---SATYTCHVA--NVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIA 1656
Query: 174 GMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMA 233
+ L C+ G P+ + WLK+ P+ + + I+ L I A+ D G Y C+A
Sbjct: 1657 HSLTLECKAA-GNPSPILTWLKDGVPVKANDNIRIEA-GGKKLEIMSAQEIDRGQYICVA 1714
Query: 234 ANIVAKR 240
++ ++
Sbjct: 1715 TSVAGEK 1721
Score = 36.6 bits (83), Expect = 0.11
Identities = 21/70 (30%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Query: 166 QGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSD 225
+ ++V I I L+C P + W K+ P+ S D+ + L I +A++ D
Sbjct: 2785 EAKDVIINNPISLYCET-NAAPPPTLTWYKDGHPLTSS-DKVLILPGGRVLQIPRAKVED 2842
Query: 226 SGNYTCMAAN 235
+G YTC+A N
Sbjct: 2843 AGRYTCVAVN 2852
Score = 36.2 bits (82), Expect = 0.15
Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 6/102 (5%)
Query: 136 CVAWSHLGT-SKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEWL 194
CVA + G +++ K +V + ++ P+ +V + + + C +G P + W
Sbjct: 1150 CVATNIAGNVTQAVKLNVHVP---PKIQRGPKHLKVQVGQRVDIPCNA-QGTPLPVITWS 1205
Query: 195 KNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANI 236
K + + + ++ + D L I QA SD+G YTC+A NI
Sbjct: 1206 KGGSTMLVDGEHHV-SNPDGTLSIDQATPSDAGIYTCVATNI 1246
Score = 35.0 bits (79), Expect = 0.33
Identities = 43/190 (22%), Positives = 77/190 (40%), Gaps = 25/190 (13%)
Query: 54 PHFIEEP--DDAYIIKSNPIALRCKA--RPAMQIFFKCNGEWVHQNEHVSEETLDESSGL 109
PH + E +D + + + L C+ P +I + +G+ + + DE+ +
Sbjct: 2478 PHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQE---------DEAHHI 2528
Query: 110 KVREVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRI----AYLRKNFEQDP 165
F+ +T QV P C+A S G KSR S+ + + +P
Sbjct: 2529 ISGGRFLQITNVQV-----PHTGRYTCLASSPAG-HKSRSFSLNVFVSPTIAGVGSDGNP 2582
Query: 166 QGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSD 225
+ V + L C P A + W K+ P++S ++ I L I A+ +
Sbjct: 2583 EDVTVILNSPTSLVCEA-YSYPPATITWFKDGTPLESNRNIRI-LPGGRTLQILNAQEDN 2640
Query: 226 SGNYTCMAAN 235
+G Y+C+A N
Sbjct: 2641 AGRYSCVATN 2650
Score = 34.3 bits (77), Expect = 0.57
Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Query: 172 IEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTC 231
++ I + CR G P ++ WLKN P+ + A + I +A++SD YTC
Sbjct: 3356 VDTSINIECRAT-GTPPPQINWLKNGLPLPLSSHIRL-LAAGQVIRIVRAQVSDVAVYTC 3413
Query: 232 MAAN 235
+A+N
Sbjct: 3414 VASN 3417
Score = 33.9 bits (76), Expect = 0.74
Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Query: 185 GVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVA-KRRSL 243
G P E+ W K+ +P+ ++ +I L I ++ +G YTC+A++ K RS
Sbjct: 2505 GNPVPEITWHKDGQPLQEDEAHHI-ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563
Query: 244 SATVVV 249
S V V
Sbjct: 2564 SLNVFV 2569
Score = 33.9 bits (76), Expect = 0.74
Identities = 26/116 (22%), Positives = 52/116 (44%), Gaps = 5/116 (4%)
Query: 136 CVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEWLK 195
C+A + GT + R+ +++ ++ + P V + L C G+P + W K
Sbjct: 3783 CMATNAAGTDR-RRIDLQV-HVPPSIAPGPTNMTVIVNVQTTLACEAT-GIPKPSINWRK 3839
Query: 196 NEEPIDSEQDEN-IDTRADHNLIIRQARLSDSGNYTCMAANIVA-KRRSLSATVVV 249
N ++ +Q++N + +L+I + D+ Y C N +R++ TV V
Sbjct: 3840 NGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQV 3895
Score = 33.5 bits (75), Expect = 0.97
Identities = 20/87 (22%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 165 PQGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLI-IRQARL 223
P V + + L C+ +G P ++ W K+ +P+ D N++ ++ ++ AR
Sbjct: 1460 PNEVSVVLNRDVALECQV-KGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNARR 1517
Query: 224 SDSGNYTCMAANIVAKR-RSLSATVVV 249
+D G Y C +N K+ + + T+ +
Sbjct: 1518 NDKGRYQCTVSNAAGKQAKDIKLTIYI 1544
Score = 31.2 bits (69), Expect = 4.8
Identities = 41/181 (22%), Positives = 75/181 (41%), Gaps = 28/181 (15%)
Query: 66 IKSNPIALRCKA--RPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVREVFINVTRQQV 123
I+ P+ L CKA P + W + E +S + S+G ++ ++
Sbjct: 993 IEGIPVTLPCKASGNPKPSVI------WSKKGELISTSSAKFSAGADGSLYVVSPGGEES 1046
Query: 124 EDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQG--REVPIEGMIV---- 177
++ C A + G +K RK + + Y+R D +G ++ P+E ++
Sbjct: 1047 GEY--------VCTATNTAGYAK-RKVQLTV-YVRPRVFGDQRGLSQDKPVEISVLAGEE 1096
Query: 178 --LHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAAN 235
L C + +P + W K + I + + ++ I + R SDSG Y C+A N
Sbjct: 1097 VTLPCEV-KSLPPPIITWAKETQLISPFSPRHTFLPSG-SMKITETRTSDSGMYLCVATN 1154
Query: 236 I 236
I
Sbjct: 1155 I 1155
Score = 30.8 bits (68), Expect = 6.3
Identities = 19/66 (28%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 170 VPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNY 229
V + + V+ C+ G+P +V+W K + + ID L I++ + D+G+Y
Sbjct: 713 VALGDITVMECKT-SGIPPPQVKWFKGDLELRPSTFLIIDPLLGL-LKIQETQDLDAGDY 770
Query: 230 TCMAAN 235
TC+A N
Sbjct: 771 TCVAIN 776
>gi|40317628 thrombospondin 2 precursor [Homo sapiens]
Length = 1172
Score = 110 bits (276), Expect = 5e-24
Identities = 56/149 (37%), Positives = 76/149 (51%), Gaps = 5/149 (3%)
Query: 219 RQARLSDSGNYTCMAANIVAKRRSLS-ATVVVYVNGGWSSWTEWSACNVRCGRGWQKRSR 277
++ R D + TC+ +I + SLS + +GGWS W+ WS+C+V CG G R R
Sbjct: 403 QRGRSCDVTSNTCLGPSIQTRACSLSKCDTRIRQDGGWSHWSPWSSCSVTCGVGNITRIR 462
Query: 278 TCTNPAPLNGGAFCEGMSVQKITCTSL-CPVDGSWEVWSEWSVCSPECE---HLRIRECT 333
C +P P GG C+G + C CP+DG W WS WS C+ C R R C
Sbjct: 463 LCNSPVPQMGGKNCKGSGRETKACQGAPCPIDGRWSPWSPWSACTVTCAGGIRERTRVCN 522
Query: 334 APPPRNGGKFCEGLSQESENCTDGLCILD 362
+P P+ GGK C G QE + C C +D
Sbjct: 523 SPEPQYGGKACVGDVQERQMCNKRSCPVD 551
Score = 91.7 bits (226), Expect = 3e-18
Identities = 52/141 (36%), Positives = 68/141 (48%), Gaps = 13/141 (9%)
Query: 230 TCMAANIVAKRRSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGA 289
TC + + V S V GWS W EW+ C+V CG G Q+R R+C +
Sbjct: 359 TCASPSFVEGECCPSCLHSVDGEEGWSPWAEWTQCSVTCGSGTQQRGRSCDVTSNT---- 414
Query: 290 FCEGMSVQKITCT-SLCPV----DGSWEVWSEWSVCSPEC---EHLRIRECTAPPPRNGG 341
C G S+Q C+ S C DG W WS WS CS C RIR C +P P+ GG
Sbjct: 415 -CLGPSIQTRACSLSKCDTRIRQDGGWSHWSPWSSCSVTCGVGNITRIRLCNSPVPQMGG 473
Query: 342 KFCEGLSQESENCTDGLCILD 362
K C+G +E++ C C +D
Sbjct: 474 KNCKGSGRETKACQGAPCPID 494
>gi|147904700 semaphorin 5A [Homo sapiens]
Length = 1074
Score = 110 bits (275), Expect = 6e-24
Identities = 51/113 (45%), Positives = 60/113 (53%), Gaps = 4/113 (3%)
Query: 251 VNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSL-CPVDG 309
VNG WS+WT WS C+ C RG + R R C NP P GG C G S++ C L CPVDG
Sbjct: 783 VNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPVDG 842
Query: 310 SWEVWSEWSVCSPEC---EHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLC 359
W WS W+ CS C ++R R C+ P P GG C GL E C C
Sbjct: 843 VWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPC 895
Score = 88.2 bits (217), Expect = 3e-17
Identities = 42/105 (40%), Positives = 56/105 (53%), Gaps = 5/105 (4%)
Query: 251 VNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITC-TSLCPVDG 309
V+G WS W+ W+ C+ CG G R+R+C+NPAP GG C G+ ++ C T CP
Sbjct: 840 VDGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPE-- 897
Query: 310 SWEVWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENC 354
SW WS+WS C +R R+C P G C G + ES C
Sbjct: 898 SWSEWSDWSECEASGVQVRARQCILLFPM--GSQCSGNTTESRPC 940
Score = 87.4 bits (215), Expect = 6e-17
Identities = 41/113 (36%), Positives = 55/113 (48%), Gaps = 11/113 (9%)
Query: 252 NGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTS--LCPVDG 309
NGGW+ WT WS C+ CG G+Q R R+C+NP P +GG C G + ++ C LCP
Sbjct: 595 NGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHM 654
Query: 310 SWEVWSEWSVCSPECE---HLRIRECTAPPPRNGGKFCEGLSQESENCTDGLC 359
W W W C+ +C R R C G C G + E ++C C
Sbjct: 655 FWTGWGPWERCTAQCGGGIQARRRIC------ENGPDCAGCNVEYQSCNTNPC 701
Score = 77.8 bits (190), Expect = 4e-14
Identities = 39/114 (34%), Positives = 58/114 (50%), Gaps = 10/114 (8%)
Query: 251 VNGGWSSWTEWSACNVRCGRGWQK---RSRTCTNPAPLNGGAFCEGMSVQKITCTSLCPV 307
V+G + W+ W+ C G R+R+C +PAP GG CEG ++ C+
Sbjct: 539 VDGHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSR---- 594
Query: 308 DGSWEVWSEWSVCSPECE---HLRIRECTAPPPRNGGKFCEGLSQESENCTDGL 358
+G W W+ WS CS C +R R C+ P PR+GG+ C G ++E C + L
Sbjct: 595 NGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHL 648
Score = 48.1 bits (113), Expect = 4e-05
Identities = 23/59 (38%), Positives = 30/59 (50%), Gaps = 3/59 (5%)
Query: 307 VDGSWEVWSEWSVCSPECEH---LRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILD 362
V+G+W W+ WS CS +C R R C P P+ GG C G S E + C C +D
Sbjct: 783 VNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPVD 841
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/64 (37%), Positives = 30/64 (46%), Gaps = 11/64 (17%)
Query: 303 SLCP-----VDGSWEVWSEWSVCSPECEHL------RIRECTAPPPRNGGKFCEGLSQES 351
S CP VDG + VWS W+ C+ R R C +P P+ GG CEG E
Sbjct: 530 SACPTRNLTVDGHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEI 589
Query: 352 ENCT 355
NC+
Sbjct: 590 ANCS 593
>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
Length = 1151
Score = 106 bits (265), Expect = 9e-23
Identities = 48/113 (42%), Positives = 61/113 (53%), Gaps = 4/113 (3%)
Query: 251 VNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCT-SLCPVDG 309
V+GGW++W WS+C+ C G++ R RTCTNP P NGG C G + + C CPV G
Sbjct: 852 VSGGWAAWGPWSSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAEYQDCNPQACPVRG 911
Query: 310 SWEVWSEWSVCSPEC---EHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLC 359
+W W+ WS CS C + R R CT+P P G C GL E C C
Sbjct: 912 AWSCWTSWSPCSASCGGGHYQRTRSCTSPAPSPGEDICLGLHTEEALCATQAC 964
Score = 90.1 bits (222), Expect = 9e-18
Identities = 58/173 (33%), Positives = 79/173 (45%), Gaps = 30/173 (17%)
Query: 251 VNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITC-TSLCPVDG 309
V G WS WT WS C+ CG G +R+R+CT+PAP G C G+ ++ C T CP
Sbjct: 909 VRGAWSCWTSWSPCSASCGGGHYQRTRSCTSPAPSPGEDICLGLHTEEALCATQACP--E 966
Query: 310 SWEVWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILDKKPLHEI 369
W WSEWS C+ + R R C P G C G S +S C P EI
Sbjct: 967 GWSPWSEWSKCTDDGAQSRSRHCEELLP--GSSACAGNSSQSRPC----------PYSEI 1014
Query: 370 ----KPQSIENASDIALYS-----------GLGAAVVAVAVLVIGVTLYRRSQ 407
S+E A+D A ++ LG+ ++ +AV + R+SQ
Sbjct: 1015 PVILPASSMEEATDCAGFNLIHLVATGISCFLGSGLLTLAVYLSCQHCQRQSQ 1067
Score = 85.9 bits (211), Expect = 2e-16
Identities = 42/113 (37%), Positives = 54/113 (47%), Gaps = 11/113 (9%)
Query: 252 NGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITC--TSLCPVDG 309
NG W+ W+ W+ C+ CG G+Q R R+C+NPAP +GG C G S ++ C + CPV
Sbjct: 664 NGAWTPWSSWALCSTSCGIGFQVRQRSCSNPAPRHGGRICVGKSREERFCNENTPCPVPI 723
Query: 310 SWEVWSEWSVCSPEC---EHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLC 359
W W WS CS C R R C G C G E + C C
Sbjct: 724 FWASWGSWSKCSSNCGGGMQSRRRAC------ENGNSCLGCGVEFKTCNPEGC 770
Score = 80.1 bits (196), Expect = 9e-15
Identities = 46/144 (31%), Positives = 67/144 (46%), Gaps = 15/144 (10%)
Query: 219 RQARLSDSGNYTCMAANIVAKRRSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQK---R 275
R + L DS N + NI A V +GG+ W+ W C G R
Sbjct: 581 RCSTLEDSSNMSLWTQNITA-----CPVRNVTRDGGFGPWSPWQPCEHLDGDNSGSCLCR 635
Query: 276 SRTCTNPAPLNGGAFCEGMSVQKITCTSLCPVDGSWEVWSEWSVCSPECE---HLRIREC 332
+R+C +P P GG C G ++ C+ +G+W WS W++CS C +R R C
Sbjct: 636 ARSCDSPRPRCGGLDCLGPAIHIANCSR----NGAWTPWSSWALCSTSCGIGFQVRQRSC 691
Query: 333 TAPPPRNGGKFCEGLSQESENCTD 356
+ P PR+GG+ C G S+E C +
Sbjct: 692 SNPAPRHGGRICVGKSREERFCNE 715
Score = 66.2 bits (160), Expect = 1e-10
Identities = 48/165 (29%), Positives = 67/165 (40%), Gaps = 31/165 (18%)
Query: 222 RLSDSGNYTCMAANIVAKRRSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQK------- 274
R ++GN +C+ + K + V N + WT W NV G Q+
Sbjct: 747 RACENGN-SCLGCGVEFKTCNPEGCPEVRRN---TPWTPWLPVNVTQGGARQEQRFRFTC 802
Query: 275 -------------RSRTCTNPAPLNGGAFCEGMSVQKITC----TSLCPVDGSWEVWSEW 317
R RT T P +G C+ ++ ++ TS V G W W W
Sbjct: 803 RAPLADPHGLQFGRRRTETRTCPADGSGSCDTDALVEVLLRSGSTSPHTVSGGWAAWGPW 862
Query: 318 SVCSPECE---HLRIRECTAPPPRNGGKFCEGLSQESENCTDGLC 359
S CS +CE +R R CT P PRNGG C G + E ++C C
Sbjct: 863 SSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAEYQDCNPQAC 907
>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor
[Homo sapiens]
Length = 1584
Score = 102 bits (255), Expect = 1e-21
Identities = 77/238 (32%), Positives = 103/238 (43%), Gaps = 29/238 (12%)
Query: 134 CQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEW 193
C A G + SR S+R R+ E + ++ P G PAAE EW
Sbjct: 309 CNREACGPAGRTSSRSQSLRSTDARRREELGDELQQFGFPA-------PQTGDPAAE-EW 360
Query: 194 LKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVAKRRSLSATVVVYVNG 253
S E TR R S +Y+ + + ++R + + V V+G
Sbjct: 361 -SPWSVCSSTCGEGWQTRT---------RFCVSSSYSTQCSGPLREQRLCNNSAVCPVHG 410
Query: 254 GWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCT-SLCP---VDG 309
W W+ WS C+ CGRG++ R+RTC P GG CEG Q C +LCP VDG
Sbjct: 411 AWDEWSPWSLCSSTCGRGFRDRTRTCR--PPQFGGNPCEGPEKQTKFCNIALCPGRAVDG 468
Query: 310 SWEVWSEWSVCSPEC---EHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILDKK 364
+W WS WS CS C R REC P GG C+G E+ +C C +D K
Sbjct: 469 NWNEWSSWSACSASCSQGRQQRTRECNG--PSYGGAECQGHWVETRDCFLQQCPVDGK 524
Score = 90.5 bits (223), Expect = 7e-18
Identities = 44/113 (38%), Positives = 58/113 (51%), Gaps = 8/113 (7%)
Query: 251 VNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITC-TSLCPVDG 309
V+G W+ W+ WSAC+ C +G Q+R+R C P+ GGA C+G V+ C CPVDG
Sbjct: 466 VDGNWNEWSSWSACSASCSQGRQQRTRECNGPS--YGGAECQGHWVETRDCFLQQCPVDG 523
Query: 310 SWEVWSEWSVCSPEC---EHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLC 359
W+ W+ W CS C R R C+ P GG C+G E C C
Sbjct: 524 KWQAWASWGSCSVTCGAGSQRRERVCSG--PFFGGAACQGPQDEYRQCGTQRC 574
Score = 54.7 bits (130), Expect = 4e-07
Identities = 24/57 (42%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
Query: 251 VNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITC-TSLCP 306
V+G W +W W +C+V CG G Q+R R C+ P GGA C+G + C T CP
Sbjct: 521 VDGKWQAWASWGSCSVTCGAGSQRRERVCS--GPFFGGAACQGPQDEYRQCGTQRCP 575
Score = 49.3 bits (116), Expect = 2e-05
Identities = 41/145 (28%), Positives = 50/145 (34%), Gaps = 45/145 (31%)
Query: 253 GGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCT---------- 302
GGW W+ W C CG G Q R+RTC PAP G CEG+ + C
Sbjct: 262 GGWKLWSLWGECTRDCGGGLQTRTRTCL-PAPGVEGGGCEGVLEEGRQCNREACGPAGRT 320
Query: 303 -----SLCPVDG-----------------------SWEVWSEWSVCSPECE---HLRIRE 331
SL D + E WS WSVCS C R R
Sbjct: 321 SSRSQSLRSTDARRREELGDELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRF 380
Query: 332 CTAPPPRNGGKFCEGLSQESENCTD 356
C + + C G +E C +
Sbjct: 381 CVS---SSYSTQCSGPLREQRLCNN 402
Score = 41.2 bits (95), Expect = 0.005
Identities = 19/54 (35%), Positives = 25/54 (46%), Gaps = 4/54 (7%)
Query: 309 GSWEVWSEWSVCSPECE---HLRIRECTAPPPRNGGKFCEGLSQESENCTDGLC 359
G W++WS W C+ +C R R C P GG CEG+ +E C C
Sbjct: 262 GGWKLWSLWGECTRDCGGGLQTRTRTCLPAPGVEGGG-CEGVLEEGRQCNREAC 314
>gi|40317626 thrombospondin 1 precursor [Homo sapiens]
Length = 1170
Score = 99.8 bits (247), Expect = 1e-20
Identities = 53/153 (34%), Positives = 76/153 (49%), Gaps = 5/153 (3%)
Query: 215 NLIIRQARLSDSGNYTCMAANIVAKRRSLSATVVVYV-NGGWSSWTEWSACNVRCGRGWQ 273
N I ++ R DS N C +++ + + + +GGWS W+ WS+C+V CG G
Sbjct: 397 NGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVI 456
Query: 274 KRSRTCTNPAPLNGGAFCEGMSVQKITC-TSLCPVDGSWEVWSEWSVCSPEC---EHLRI 329
R R C +P+P G CEG + + C CP++G W WS W +CS C R
Sbjct: 457 TRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRS 516
Query: 330 RECTAPPPRNGGKFCEGLSQESENCTDGLCILD 362
R C P P+ GGK C G E++ C C +D
Sbjct: 517 RLCNNPTPQFGGKDCVGDVTENQICNKQDCPID 549
Score = 92.4 bits (228), Expect = 2e-18
Identities = 48/114 (42%), Positives = 61/114 (53%), Gaps = 13/114 (11%)
Query: 254 GWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKIT-----CTSLCPVD 308
GWS W+EW++C+ CG G Q+R R+C + LN CEG SVQ T C D
Sbjct: 381 GWSPWSEWTSCSTSCGNGIQQRGRSCDS---LNNR--CEGSSVQTRTCHIQECDKRFKQD 435
Query: 309 GSWEVWSEWSVCSPECEH---LRIRECTAPPPRNGGKFCEGLSQESENCTDGLC 359
G W WS WS CS C RIR C +P P+ GK CEG ++E++ C C
Sbjct: 436 GGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDAC 489
Score = 69.3 bits (168), Expect = 2e-11
Identities = 29/60 (48%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Query: 251 VNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSL-CPVDG 309
+NGGW W+ W C+V CG G QKRSR C NP P GG C G + C CP+DG
Sbjct: 491 INGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDG 550
Score = 36.6 bits (83), Expect = 0.11
Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 22/94 (23%)
Query: 278 TCTNPAPLNGGAFCEGMSVQKITCTSL-------CP-------VDGSWEVWSEWSVCSPE 323
+CT N C+ +S + C++ CP D W WSEW+ CS
Sbjct: 335 SCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTS 394
Query: 324 CEH---LRIRECTAPPPRNGGKFCEGLSQESENC 354
C + R R C + R CEG S ++ C
Sbjct: 395 CGNGIQQRGRSCDSLNNR-----CEGSSVQTRTC 423
>gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens]
Length = 1522
Score = 98.2 bits (243), Expect = 3e-20
Identities = 51/123 (41%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 241 RSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKIT 300
R + T + V+G W W+ WS C+ CGRG + R+R+CT P GG CEG
Sbjct: 334 RVCNNTALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCT--PPQYGGRPCEGPETHHKP 391
Query: 301 CT-SLCPVDGSWEVWSEWSVCSPECEH---LRIRECTAPPPRNGGKFCEGLSQESENCTD 356
C +LCPVDG W+ WS WS CS C + R R+CTA +GG C G ES C +
Sbjct: 392 CNIALCPVDGQWQEWSSWSQCSVTCSNGTQQRSRQCTA--AAHGGSECRGPWAESRECYN 449
Query: 357 GLC 359
C
Sbjct: 450 PEC 452
Score = 97.8 bits (242), Expect = 4e-20
Identities = 49/114 (42%), Positives = 63/114 (55%), Gaps = 11/114 (9%)
Query: 254 GWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITC--TSLCPVDGSW 311
G W++WS C+V CG+G Q R+RTC +P G C G + C T+LCPV G W
Sbjct: 293 GVEEWSQWSTCSVTCGQGSQVRTRTCVSPY----GTHCSGPLRESRVCNNTALCPVHGVW 348
Query: 312 EVWSEWSVCSPEC---EHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILD 362
E WS WS+CS C + R R CT PP+ GG+ CEG + C LC +D
Sbjct: 349 EEWSPWSLCSFTCGRGQRTRTRSCT--PPQYGGRPCEGPETHHKPCNIALCPVD 400
Score = 84.0 bits (206), Expect = 6e-16
Identities = 42/113 (37%), Positives = 56/113 (49%), Gaps = 8/113 (7%)
Query: 251 VNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSL-CPVDG 309
V+G W W+ WS C+V C G Q+RSR CT A +GG+ C G + C + C +G
Sbjct: 399 VDGQWQEWSSWSQCSVTCSNGTQQRSRQCT--AAAHGGSECRGPWAESRECYNPECTANG 456
Query: 310 SWEVWSEWSVCSPECE---HLRIRECTAPPPRNGGKFCEGLSQESENCTDGLC 359
W W WS CS C+ RIR C G+ CEG +E C++ C
Sbjct: 457 QWNQWGHWSGCSKSCDGGWERRIRTCQGAVIT--GQQCEGTGEEVRRCSEQRC 507
Score = 47.4 bits (111), Expect = 6e-05
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 10/65 (15%)
Query: 252 NGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCT--------S 303
NG W+ W WS C+ C GW++R RTC + G CEG + C+
Sbjct: 455 NGQWNQWGHWSGCSKSCDGGWERRIRTC--QGAVITGQQCEGTGEEVRRCSEQRCPAPYE 512
Query: 304 LCPVD 308
+CP D
Sbjct: 513 ICPED 517
>gi|224994173 roundabout 1 isoform d [Homo sapiens]
Length = 1551
Score = 96.3 bits (238), Expect = 1e-19
Identities = 66/202 (32%), Positives = 96/202 (47%), Gaps = 17/202 (8%)
Query: 54 PHFIEEPDDAYIIKSNPIALRCKA--RPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKV 111
P +E P D + K P L CKA RP I EW E V + D S
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTI------EWYKGGERVETDKDDPRSH--- 79
Query: 112 REVFINVTRQQVEDFHG----PEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQG 167
R + + + + HG P++ CVA ++LG + S AS+ +A LR +F Q+P
Sbjct: 80 RMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSD 139
Query: 168 REVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSG 227
V + V+ C+PP G P + W K+ P+D ++DE I R L+I R SD+G
Sbjct: 140 VMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLD-DKDERITIRGG-KLMITYTRKSDAG 197
Query: 228 NYTCMAANIVAKRRSLSATVVV 249
Y C+ N+V +R S A + V
Sbjct: 198 KYVCVGTNMVGERESEVAELTV 219
Score = 55.5 bits (132), Expect = 2e-07
Identities = 50/199 (25%), Positives = 82/199 (41%), Gaps = 24/199 (12%)
Query: 56 FIEEPDDAYIIKSNPIALRC---KARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVR 112
F + P D + P + C + P I +K +G + DE ++
Sbjct: 133 FRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDK--------DERITIRGG 184
Query: 113 EVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPI 172
++ I TR+ + CV + +G +S A + + R +F + P V +
Sbjct: 185 KLMITYTRKSDAGKY-------VCVGTNMVGERESEVAELTVLE-RPSFVKRPSNLAVTV 236
Query: 173 EGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCM 232
+ C G P V W K++ + + E R DH L IR+ D G+YTC+
Sbjct: 237 DDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRYE---IRDDHTLKIRKVTAGDMGSYTCV 292
Query: 233 AANIVAKRRSLSATVVVYV 251
A N+V K + SAT+ V V
Sbjct: 293 AENMVGKAEA-SATLTVQV 310
Score = 53.5 bits (127), Expect = 9e-07
Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 19/189 (10%)
Query: 54 PHFIEEPDDAYIIKSNPIALRCKA--RPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKV 111
PHF+ +P D + + +C+A P IF++ G QN S + SS V
Sbjct: 315 PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGS---QNLLFSYQPPQSSSRFSV 371
Query: 112 REVF-INVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKN-----FEQDP 165
+ + +T Q D Y CQ + ++ S KA + + + + Q P
Sbjct: 372 SQTGDLTITNVQRSDVGY---YICQTL---NVAGSIITKAYLEVTDVIADRPPPVIRQGP 425
Query: 166 QGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSD 225
+ V ++G VL C G P + W K+ + S QD I + L IR A+L D
Sbjct: 426 VNQTVAVDGTFVLSC-VATGSPVPTILWRKDGVLV-STQDSRIKQLENGVLQIRYAKLGD 483
Query: 226 SGNYTCMAA 234
+G YTC+A+
Sbjct: 484 TGRYTCIAS 492
Score = 33.1 bits (74), Expect = 1.3
Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 17/86 (19%)
Query: 178 LHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARL------------SD 225
L+C+ EG P +EW K E +++++D D R+ H +++ L D
Sbjct: 48 LNCKA-EGRPTPTIEWYKGGERVETDKD---DPRS-HRMLLPSGSLFFLRIVHGRKSRPD 102
Query: 226 SGNYTCMAANIVAKRRSLSATVVVYV 251
G Y C+A N + + S +A++ V +
Sbjct: 103 EGVYVCVARNYLGEAVSHNASLEVAI 128
>gi|224994171 roundabout 1 isoform c [Homo sapiens]
Length = 1606
Score = 96.3 bits (238), Expect = 1e-19
Identities = 66/202 (32%), Positives = 96/202 (47%), Gaps = 17/202 (8%)
Query: 54 PHFIEEPDDAYIIKSNPIALRCKA--RPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKV 111
P +E P D + K P L CKA RP I EW E V + D S
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTI------EWYKGGERVETDKDDPRSH--- 79
Query: 112 REVFINVTRQQVEDFHG----PEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQG 167
R + + + + HG P++ CVA ++LG + S AS+ +A LR +F Q+P
Sbjct: 80 RMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSD 139
Query: 168 REVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSG 227
V + V+ C+PP G P + W K+ P+D ++DE I R L+I R SD+G
Sbjct: 140 VMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLD-DKDERITIRGG-KLMITYTRKSDAG 197
Query: 228 NYTCMAANIVAKRRSLSATVVV 249
Y C+ N+V +R S A + V
Sbjct: 198 KYVCVGTNMVGERESEVAELTV 219
Score = 55.5 bits (132), Expect = 2e-07
Identities = 50/199 (25%), Positives = 82/199 (41%), Gaps = 24/199 (12%)
Query: 56 FIEEPDDAYIIKSNPIALRC---KARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVR 112
F + P D + P + C + P I +K +G + DE ++
Sbjct: 133 FRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDK--------DERITIRGG 184
Query: 113 EVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPI 172
++ I TR+ + CV + +G +S A + + R +F + P V +
Sbjct: 185 KLMITYTRKSDAGKY-------VCVGTNMVGERESEVAELTVLE-RPSFVKRPSNLAVTV 236
Query: 173 EGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCM 232
+ C G P V W K++ + + E R DH L IR+ D G+YTC+
Sbjct: 237 DDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRYE---IRDDHTLKIRKVTAGDMGSYTCV 292
Query: 233 AANIVAKRRSLSATVVVYV 251
A N+V K + SAT+ V V
Sbjct: 293 AENMVGKAEA-SATLTVQV 310
Score = 53.5 bits (127), Expect = 9e-07
Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 19/189 (10%)
Query: 54 PHFIEEPDDAYIIKSNPIALRCKA--RPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKV 111
PHF+ +P D + + +C+A P IF++ G QN S + SS V
Sbjct: 315 PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGS---QNLLFSYQPPQSSSRFSV 371
Query: 112 REVF-INVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKN-----FEQDP 165
+ + +T Q D Y CQ + ++ S KA + + + + Q P
Sbjct: 372 SQTGDLTITNVQRSDVGY---YICQTL---NVAGSIITKAYLEVTDVIADRPPPVIRQGP 425
Query: 166 QGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSD 225
+ V ++G VL C G P + W K+ + S QD I + L IR A+L D
Sbjct: 426 VNQTVAVDGTFVLSC-VATGSPVPTILWRKDGVLV-STQDSRIKQLENGVLQIRYAKLGD 483
Query: 226 SGNYTCMAA 234
+G YTC+A+
Sbjct: 484 TGRYTCIAS 492
Score = 33.1 bits (74), Expect = 1.3
Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 17/86 (19%)
Query: 178 LHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARL------------SD 225
L+C+ EG P +EW K E +++++D D R+ H +++ L D
Sbjct: 48 LNCKA-EGRPTPTIEWYKGGERVETDKD---DPRS-HRMLLPSGSLFFLRIVHGRKSRPD 102
Query: 226 SGNYTCMAANIVAKRRSLSATVVVYV 251
G Y C+A N + + S +A++ V +
Sbjct: 103 EGVYVCVARNYLGEAVSHNASLEVAI 128
>gi|19743806 roundabout 1 isoform b [Homo sapiens]
Length = 1612
Score = 96.3 bits (238), Expect = 1e-19
Identities = 66/202 (32%), Positives = 96/202 (47%), Gaps = 17/202 (8%)
Query: 54 PHFIEEPDDAYIIKSNPIALRCKA--RPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKV 111
P +E P D + K P L CKA RP I EW E V + D S
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTI------EWYKGGERVETDKDDPRSH--- 79
Query: 112 REVFINVTRQQVEDFHG----PEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQG 167
R + + + + HG P++ CVA ++LG + S AS+ +A LR +F Q+P
Sbjct: 80 RMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSD 139
Query: 168 REVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSG 227
V + V+ C+PP G P + W K+ P+D ++DE I R L+I R SD+G
Sbjct: 140 VMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLD-DKDERITIRGG-KLMITYTRKSDAG 197
Query: 228 NYTCMAANIVAKRRSLSATVVV 249
Y C+ N+V +R S A + V
Sbjct: 198 KYVCVGTNMVGERESEVAELTV 219
Score = 54.3 bits (129), Expect = 5e-07
Identities = 49/197 (24%), Positives = 81/197 (41%), Gaps = 24/197 (12%)
Query: 56 FIEEPDDAYIIKSNPIALRC---KARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVR 112
F + P D + P + C + P I +K +G + DE ++
Sbjct: 133 FRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDK--------DERITIRGG 184
Query: 113 EVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPI 172
++ I TR+ + CV + +G +S A + + R +F + P V +
Sbjct: 185 KLMITYTRKSDAGKY-------VCVGTNMVGERESEVAELTVLE-RPSFVKRPSNLAVTV 236
Query: 173 EGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCM 232
+ C G P V W K++ + + E R DH L IR+ D G+YTC+
Sbjct: 237 DDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRYE---IRDDHTLKIRKVTAGDMGSYTCV 292
Query: 233 AANIVAKRRSLSATVVV 249
A N+V K + SAT+ V
Sbjct: 293 AENMVGKAEA-SATLTV 308
Score = 53.5 bits (127), Expect = 9e-07
Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 19/189 (10%)
Query: 54 PHFIEEPDDAYIIKSNPIALRCKA--RPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKV 111
PHF+ +P D + + +C+A P IF++ G QN S + SS V
Sbjct: 312 PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGS---QNLLFSYQPPQSSSRFSV 368
Query: 112 REVF-INVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKN-----FEQDP 165
+ + +T Q D Y CQ + ++ S KA + + + + Q P
Sbjct: 369 SQTGDLTITNVQRSDVGY---YICQTL---NVAGSIITKAYLEVTDVIADRPPPVIRQGP 422
Query: 166 QGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSD 225
+ V ++G VL C G P + W K+ + S QD I + L IR A+L D
Sbjct: 423 VNQTVAVDGTFVLSC-VATGSPVPTILWRKDGVLV-STQDSRIKQLENGVLQIRYAKLGD 480
Query: 226 SGNYTCMAA 234
+G YTC+A+
Sbjct: 481 TGRYTCIAS 489
Score = 33.1 bits (74), Expect = 1.3
Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 17/86 (19%)
Query: 178 LHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARL------------SD 225
L+C+ EG P +EW K E +++++D D R+ H +++ L D
Sbjct: 48 LNCKA-EGRPTPTIEWYKGGERVETDKD---DPRS-HRMLLPSGSLFFLRIVHGRKSRPD 102
Query: 226 SGNYTCMAANIVAKRRSLSATVVVYV 251
G Y C+A N + + S +A++ V +
Sbjct: 103 EGVYVCVARNYLGEAVSHNASLEVAI 128
>gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo
sapiens]
Length = 1562
Score = 96.3 bits (238), Expect = 1e-19
Identities = 66/202 (32%), Positives = 96/202 (47%), Gaps = 17/202 (8%)
Query: 54 PHFIEEPDDAYIIKSNPIALRCKA--RPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKV 111
P +E P D + K P L CKA RP I EW E V + D S
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTI------EWYKGGERVETDKDDPRSH--- 79
Query: 112 REVFINVTRQQVEDFHG----PEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQG 167
R + + + + HG P++ CVA ++LG + S AS+ +A LR +F Q+P
Sbjct: 80 RMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSD 139
Query: 168 REVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSG 227
V + V+ C+PP G P + W K+ P+D ++DE I R L+I R SD+G
Sbjct: 140 VMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLD-DKDERITIRGG-KLMITYTRKSDAG 197
Query: 228 NYTCMAANIVAKRRSLSATVVV 249
Y C+ N+V +R S A + V
Sbjct: 198 KYVCVGTNMVGERESEVAELTV 219
Score = 55.5 bits (132), Expect = 2e-07
Identities = 50/199 (25%), Positives = 82/199 (41%), Gaps = 24/199 (12%)
Query: 56 FIEEPDDAYIIKSNPIALRC---KARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVR 112
F + P D + P + C + P I +K +G + DE ++
Sbjct: 133 FRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDK--------DERITIRGG 184
Query: 113 EVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPI 172
++ I TR+ + CV + +G +S A + + R +F + P V +
Sbjct: 185 KLMITYTRKSDAGKY-------VCVGTNMVGERESEVAELTVLE-RPSFVKRPSNLAVTV 236
Query: 173 EGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCM 232
+ C G P V W K++ + + E R DH L IR+ D G+YTC+
Sbjct: 237 DDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRYE---IRDDHTLKIRKVTAGDMGSYTCV 292
Query: 233 AANIVAKRRSLSATVVVYV 251
A N+V K + SAT+ V V
Sbjct: 293 AENMVGKAEA-SATLTVQV 310
Score = 53.5 bits (127), Expect = 9e-07
Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 19/189 (10%)
Query: 54 PHFIEEPDDAYIIKSNPIALRCKA--RPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKV 111
PHF+ +P D + + +C+A P IF++ G QN S + SS V
Sbjct: 315 PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGS---QNLLFSYQPPQSSSRFSV 371
Query: 112 REVF-INVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKN-----FEQDP 165
+ + +T Q D Y CQ + ++ S KA + + + + Q P
Sbjct: 372 SQTGDLTITNVQRSDVGY---YICQTL---NVAGSIITKAYLEVTDVIADRPPPVIRQGP 425
Query: 166 QGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSD 225
+ V ++G VL C G P + W K+ + S QD I + L IR A+L D
Sbjct: 426 VNQTVAVDGTFVLSC-VATGSPVPTILWRKDGVLV-STQDSRIKQLENGVLQIRYAKLGD 483
Query: 226 SGNYTCMAA 234
+G YTC+A+
Sbjct: 484 TGRYTCIAS 492
Score = 33.1 bits (74), Expect = 1.3
Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 17/86 (19%)
Query: 178 LHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARL------------SD 225
L+C+ EG P +EW K E +++++D D R+ H +++ L D
Sbjct: 48 LNCKA-EGRPTPTIEWYKGGERVETDKD---DPRS-HRMLLPSGSLFFLRIVHGRKSRPD 102
Query: 226 SGNYTCMAANIVAKRRSLSATVVVYV 251
G Y C+A N + + S +A++ V +
Sbjct: 103 EGVYVCVARNYLGEAVSHNASLEVAI 128
>gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo
sapiens]
Length = 1615
Score = 96.3 bits (238), Expect = 1e-19
Identities = 66/202 (32%), Positives = 96/202 (47%), Gaps = 17/202 (8%)
Query: 54 PHFIEEPDDAYIIKSNPIALRCKA--RPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKV 111
P +E P D + K P L CKA RP I EW E V + D S
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTI------EWYKGGERVETDKDDPRSH--- 79
Query: 112 REVFINVTRQQVEDFHG----PEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQG 167
R + + + + HG P++ CVA ++LG + S AS+ +A LR +F Q+P
Sbjct: 80 RMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSD 139
Query: 168 REVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSG 227
V + V+ C+PP G P + W K+ P+D ++DE I R L+I R SD+G
Sbjct: 140 VMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLD-DKDERITIRGG-KLMITYTRKSDAG 197
Query: 228 NYTCMAANIVAKRRSLSATVVV 249
Y C+ N+V +R S A + V
Sbjct: 198 KYVCVGTNMVGERESEVAELTV 219
Score = 55.5 bits (132), Expect = 2e-07
Identities = 50/199 (25%), Positives = 82/199 (41%), Gaps = 24/199 (12%)
Query: 56 FIEEPDDAYIIKSNPIALRC---KARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVR 112
F + P D + P + C + P I +K +G + DE ++
Sbjct: 133 FRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDK--------DERITIRGG 184
Query: 113 EVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPI 172
++ I TR+ + CV + +G +S A + + R +F + P V +
Sbjct: 185 KLMITYTRKSDAGKY-------VCVGTNMVGERESEVAELTVLE-RPSFVKRPSNLAVTV 236
Query: 173 EGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCM 232
+ C G P V W K++ + + E R DH L IR+ D G+YTC+
Sbjct: 237 DDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRYE---IRDDHTLKIRKVTAGDMGSYTCV 292
Query: 233 AANIVAKRRSLSATVVVYV 251
A N+V K + SAT+ V V
Sbjct: 293 AENMVGKAEA-SATLTVQV 310
Score = 53.5 bits (127), Expect = 9e-07
Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 19/189 (10%)
Query: 54 PHFIEEPDDAYIIKSNPIALRCKA--RPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKV 111
PHF+ +P D + + +C+A P IF++ G QN S + SS V
Sbjct: 315 PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGS---QNLLFSYQPPQSSSRFSV 371
Query: 112 REVF-INVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKN-----FEQDP 165
+ + +T Q D Y CQ + ++ S KA + + + + Q P
Sbjct: 372 SQTGDLTITNVQRSDVGY---YICQTL---NVAGSIITKAYLEVTDVIADRPPPVIRQGP 425
Query: 166 QGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSD 225
+ V ++G VL C G P + W K+ + S QD I + L IR A+L D
Sbjct: 426 VNQTVAVDGTFVLSC-VATGSPVPTILWRKDGVLV-STQDSRIKQLENGVLQIRYAKLGD 483
Query: 226 SGNYTCMAA 234
+G YTC+A+
Sbjct: 484 TGRYTCIAS 492
Score = 33.1 bits (74), Expect = 1.3
Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 17/86 (19%)
Query: 178 LHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARL------------SD 225
L+C+ EG P +EW K E +++++D D R+ H +++ L D
Sbjct: 48 LNCKA-EGRPTPTIEWYKGGERVETDKD---DPRS-HRMLLPSGSLFFLRIVHGRKSRPD 102
Query: 226 SGNYTCMAANIVAKRRSLSATVVVYV 251
G Y C+A N + + S +A++ V +
Sbjct: 103 EGVYVCVARNYLGEAVSHNASLEVAI 128
>gi|4506569 roundabout 1 isoform a [Homo sapiens]
Length = 1651
Score = 96.3 bits (238), Expect = 1e-19
Identities = 66/202 (32%), Positives = 96/202 (47%), Gaps = 17/202 (8%)
Query: 54 PHFIEEPDDAYIIKSNPIALRCKA--RPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKV 111
P +E P D + K P L CKA RP I EW E V + D S
Sbjct: 68 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTI------EWYKGGERVETDKDDPRSH--- 118
Query: 112 REVFINVTRQQVEDFHG----PEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQG 167
R + + + + HG P++ CVA ++LG + S AS+ +A LR +F Q+P
Sbjct: 119 RMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSD 178
Query: 168 REVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSG 227
V + V+ C+PP G P + W K+ P+D ++DE I R L+I R SD+G
Sbjct: 179 VMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLD-DKDERITIRGG-KLMITYTRKSDAG 236
Query: 228 NYTCMAANIVAKRRSLSATVVV 249
Y C+ N+V +R S A + V
Sbjct: 237 KYVCVGTNMVGERESEVAELTV 258
Score = 54.3 bits (129), Expect = 5e-07
Identities = 49/197 (24%), Positives = 81/197 (41%), Gaps = 24/197 (12%)
Query: 56 FIEEPDDAYIIKSNPIALRC---KARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVR 112
F + P D + P + C + P I +K +G + DE ++
Sbjct: 172 FRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDK--------DERITIRGG 223
Query: 113 EVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPI 172
++ I TR+ + CV + +G +S A + + R +F + P V +
Sbjct: 224 KLMITYTRKSDAGKY-------VCVGTNMVGERESEVAELTVLE-RPSFVKRPSNLAVTV 275
Query: 173 EGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCM 232
+ C G P V W K++ + + E R DH L IR+ D G+YTC+
Sbjct: 276 DDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRYE---IRDDHTLKIRKVTAGDMGSYTCV 331
Query: 233 AANIVAKRRSLSATVVV 249
A N+V K + SAT+ V
Sbjct: 332 AENMVGKAEA-SATLTV 347
Score = 53.5 bits (127), Expect = 9e-07
Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 19/189 (10%)
Query: 54 PHFIEEPDDAYIIKSNPIALRCKA--RPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKV 111
PHF+ +P D + + +C+A P IF++ G QN S + SS V
Sbjct: 351 PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGS---QNLLFSYQPPQSSSRFSV 407
Query: 112 REVF-INVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKN-----FEQDP 165
+ + +T Q D Y CQ + ++ S KA + + + + Q P
Sbjct: 408 SQTGDLTITNVQRSDVGY---YICQTL---NVAGSIITKAYLEVTDVIADRPPPVIRQGP 461
Query: 166 QGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSD 225
+ V ++G VL C G P + W K+ + S QD I + L IR A+L D
Sbjct: 462 VNQTVAVDGTFVLSC-VATGSPVPTILWRKDGVLV-STQDSRIKQLENGVLQIRYAKLGD 519
Query: 226 SGNYTCMAA 234
+G YTC+A+
Sbjct: 520 TGRYTCIAS 528
Score = 33.1 bits (74), Expect = 1.3
Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 17/86 (19%)
Query: 178 LHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARL------------SD 225
L+C+ EG P +EW K E +++++D D R+ H +++ L D
Sbjct: 87 LNCKA-EGRPTPTIEWYKGGERVETDKD---DPRS-HRMLLPSGSLFFLRIVHGRKSRPD 141
Query: 226 SGNYTCMAANIVAKRRSLSATVVVYV 251
G Y C+A N + + S +A++ V +
Sbjct: 142 EGVYVCVARNYLGEAVSHNASLEVAI 167
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 95.5 bits (236), Expect = 2e-19
Identities = 67/203 (33%), Positives = 98/203 (48%), Gaps = 17/203 (8%)
Query: 54 PHFIEEPDDAYIIKSNPIALRCKA--RPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKV 111
P +E P D + K P L CKA RP I EW E V + D S
Sbjct: 47 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTI------EWYKDGERVETDKDDPRSH--- 97
Query: 112 REVFINVTRQQVEDFHG----PEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQG 167
R + + + + HG P++ CVA ++LG + SR AS+ +A LR +F Q+P
Sbjct: 98 RMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTD 157
Query: 168 REVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSG 227
V +L C+PP G P + W K++ ID +++E I R L+I R SD+G
Sbjct: 158 VVVAAGEPAILECQPPRGHPEPTIYWKKDKVRID-DKEERISIRGG-KLMISNTRKSDAG 215
Query: 228 NYTCMAANIVAKRRSLSATVVVY 250
YTC+ N+V +R S A + V+
Sbjct: 216 MYTCVGTNMVGERDSDPAELTVF 238
Score = 47.8 bits (112), Expect = 5e-05
Identities = 46/197 (23%), Positives = 83/197 (42%), Gaps = 24/197 (12%)
Query: 56 FIEEPDDAYIIKSNPIALRC---KARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVR 112
F + P D + P L C + P I++K + V + +E ++
Sbjct: 151 FRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWK--------KDKVRIDDKEERISIRGG 202
Query: 113 EVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPI 172
++ I+ TR+ + CV + +G S A + + + R F + P + V
Sbjct: 203 KLMISNTRKSDAGMY-------TCVGTNMVGERDSDPAELTV-FERPTFLRRPINQVVLE 254
Query: 173 EGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCM 232
E + C+ +G P V W K++ + + D + D+ L I++ +D G Y C+
Sbjct: 255 EEAVEFRCQV-QGDPQPTVRWKKDDADLPRGR---YDIKDDYTLRIKKTMSTDEGTYMCI 310
Query: 233 AANIVAKRRSLSATVVV 249
A N V K + SAT+ V
Sbjct: 311 AENRVGKMEA-SATLTV 326
Score = 43.5 bits (101), Expect = 0.001
Identities = 45/187 (24%), Positives = 72/187 (38%), Gaps = 13/187 (6%)
Query: 54 PHFIEEPDDAYIIKSNPIALRC--KARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKV 111
P F+ P D + + + C K P +F++ G QN + +S V
Sbjct: 330 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGS---QNLLFPNQPQQPNSRCSV 386
Query: 112 REVF-INVTRQQVEDFHGPEDYWCQC--VAWSHLGTSKSRKASVRIAYLRKNFEQDPQGR 168
+ +T Q D Y CQ VA S L ++ V Q P +
Sbjct: 387 SPTGDLTITNIQRSD---AGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQ 443
Query: 169 EVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGN 228
+ ++G +L C+ G P + WLK +D + L I+ R+SD+G
Sbjct: 444 TLAVDGTALLKCKAT-GDPLPVISWLKEGFTFPG-RDPRATIQEQGTLQIKNLRISDTGT 501
Query: 229 YTCMAAN 235
YTC+A +
Sbjct: 502 YTCVATS 508
>gi|61888896 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2b [Homo sapiens]
Length = 1378
Score = 95.5 bits (236), Expect = 2e-19
Identities = 67/203 (33%), Positives = 98/203 (48%), Gaps = 17/203 (8%)
Query: 54 PHFIEEPDDAYIIKSNPIALRCKA--RPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKV 111
P +E P D + K P L CKA RP I EW E V + D S
Sbjct: 31 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTI------EWYKDGERVETDKDDPRSH--- 81
Query: 112 REVFINVTRQQVEDFHG----PEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQG 167
R + + + + HG P++ CVA ++LG + SR AS+ +A LR +F Q+P
Sbjct: 82 RMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTD 141
Query: 168 REVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSG 227
V +L C+PP G P + W K++ ID +++E I R L+I R SD+G
Sbjct: 142 VVVAAGEPAILECQPPRGHPEPTIYWKKDKVRID-DKEERISIRGG-KLMISNTRKSDAG 199
Query: 228 NYTCMAANIVAKRRSLSATVVVY 250
YTC+ N+V +R S A + V+
Sbjct: 200 MYTCVGTNMVGERDSDPAELTVF 222
Score = 47.8 bits (112), Expect = 5e-05
Identities = 46/197 (23%), Positives = 83/197 (42%), Gaps = 24/197 (12%)
Query: 56 FIEEPDDAYIIKSNPIALRC---KARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVR 112
F + P D + P L C + P I++K + V + +E ++
Sbjct: 135 FRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWK--------KDKVRIDDKEERISIRGG 186
Query: 113 EVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPI 172
++ I+ TR+ + CV + +G S A + + + R F + P + V
Sbjct: 187 KLMISNTRKSDAGMY-------TCVGTNMVGERDSDPAELTV-FERPTFLRRPINQVVLE 238
Query: 173 EGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCM 232
E + C+ +G P V W K++ + + D + D+ L I++ +D G Y C+
Sbjct: 239 EEAVEFRCQV-QGDPQPTVRWKKDDADLPRGR---YDIKDDYTLRIKKTMSTDEGTYMCI 294
Query: 233 AANIVAKRRSLSATVVV 249
A N V K + SAT+ V
Sbjct: 295 AENRVGKMEA-SATLTV 310
Score = 43.5 bits (101), Expect = 0.001
Identities = 45/187 (24%), Positives = 72/187 (38%), Gaps = 13/187 (6%)
Query: 54 PHFIEEPDDAYIIKSNPIALRC--KARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKV 111
P F+ P D + + + C K P +F++ G QN + +S V
Sbjct: 314 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGS---QNLLFPNQPQQPNSRCSV 370
Query: 112 REVF-INVTRQQVEDFHGPEDYWCQC--VAWSHLGTSKSRKASVRIAYLRKNFEQDPQGR 168
+ +T Q D Y CQ VA S L ++ V Q P +
Sbjct: 371 SPTGDLTITNIQRSD---AGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQ 427
Query: 169 EVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGN 228
+ ++G +L C+ G P + WLK +D + L I+ R+SD+G
Sbjct: 428 TLAVDGTALLKCKAT-GDPLPVISWLKEGFTFPG-RDPRATIQEQGTLQIKNLRISDTGT 485
Query: 229 YTCMAAN 235
YTC+A +
Sbjct: 486 YTCVATS 492
>gi|27734865 unc-5 homolog C-like [Homo sapiens]
Length = 518
Score = 95.1 bits (235), Expect = 3e-19
Identities = 99/392 (25%), Positives = 162/392 (41%), Gaps = 36/392 (9%)
Query: 550 HLGGRLVMPNTGVSLLIPHGAI----PEENSWEIYMSINQGEPSLQSDGSEVLLSPEVTC 605
H GG L++ +TG+SLLIP GA+ E S + ++ Q+ G L+SP V C
Sbjct: 110 HRGGCLMLQDTGISLLIPPGAVAVGRQERVSLILVWDLSDAPSLSQAQG---LVSPVVAC 166
Query: 606 GPPDMIVTTPFALTIPHCADVSSEHWNIHLKKRTQQGK-WEEVMSVEDESTSCYCLLDPF 664
GP P LT HCA+ S K W + + D
Sbjct: 167 GPHGASFLKPCTLTFKHCAEQPSHARTYSSNTTLLDAKVWRPL-----GRPGAHASRD-- 219
Query: 665 ACHVLLDSFGTYALTGE-PITDCAVKQLKVAVFGCMSCNSL-----DYNLRVYCVDNTPC 718
C + L F Y E P+ A K L++AVF C+ L LR+Y ++NTPC
Sbjct: 220 ECRIHLSHFSLYTCVLEAPVGREARKWLQLAVF----CSPLVPGQSHLQLRIYFLNNTPC 275
Query: 719 AFQEVVSDERHQGGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRV 778
A Q +++E+ GG+L +L F G + + I W ++CQ VP +
Sbjct: 276 ALQWALTNEQPHGGRLRGPCQLFDFNGARGDQCLKLTYISEG-WENVDDSSCQLVPHLHI 334
Query: 779 WCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQVQTSILESERETITFFAQE 838
W + P +F R + C ++ + Q + E + F A E
Sbjct: 335 W-HGKCPFR-SFCFRRKAADENE-DCSALTNEI--IVTMHTFQDGLETKYMEILRFQASE 389
Query: 839 DSTF----PAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSI-NRNLSYFAT 893
+ ++ P P ++P + +++ + + G DW+ LA + + + +
Sbjct: 390 EESWAAPPPVSQPPPCNRLPPELFEQLRMLLEPNSITGNDWRGLASHLGLCGMKIRFLSC 449
Query: 894 QSSPSAVILNLWEARHQHDGDLDSLACALEEI 925
Q SP+A IL L+E ++ +L L +E +
Sbjct: 450 QRSPAAAILELFEEQNGSLQELHYLMTVMERL 481
>gi|4505737 complement factor properdin precursor [Homo sapiens]
Length = 469
Score = 94.4 bits (233), Expect = 5e-19
Identities = 44/114 (38%), Positives = 59/114 (51%), Gaps = 12/114 (10%)
Query: 253 GGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTS--LCPVDGS 310
GGWS W W C+V C +G + R R C +PAP GG C G + + C + +CP G+
Sbjct: 137 GGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGG-HCPGQAQESEACDTQQVCPTHGA 195
Query: 311 WEVWSEWSVCSPEC-------EHLRIRECTAPPP--RNGGKFCEGLSQESENCT 355
W W W+ CS C + R R+C+AP P + GK C GL+ E CT
Sbjct: 196 WATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCT 249
Score = 82.4 bits (202), Expect = 2e-15
Identities = 40/112 (35%), Positives = 52/112 (46%), Gaps = 15/112 (13%)
Query: 251 VNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSL--CPVD 308
V GGW W S C V CG G RTC +P P +GG FC G + + C + CPVD
Sbjct: 256 VAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCPVD 315
Query: 309 GSWEVWSEWSVC------SPECEHLRIRECTAPPPRNGGKFCEGLSQESENC 354
G W+ W EWS C S C+ + P ++ G+ C G + C
Sbjct: 316 GEWDSWGEWSPCIRRNMKSISCQEI-------PGQQSRGRTCRGRKFDGHRC 360
Score = 73.6 bits (179), Expect = 8e-13
Identities = 40/123 (32%), Positives = 59/123 (47%), Gaps = 12/123 (9%)
Query: 252 NGGWSSWTEWSACNVRCGRG----WQKRSRTCTNPAPLN--GGAFCEGMSVQKITCTSL- 304
+G W++W W+ C+ C G + RSR C+ P P G C G++ ++ CT L
Sbjct: 193 HGAWATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLP 252
Query: 305 -CPVDGSWEVWSEWSVCSPEC---EHLRIRECTAPPPRNGGKFCEGLSQESENCTDGL-C 359
CPV G W W S C C + + R C P P++GG FC G + + C + C
Sbjct: 253 PCPVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPC 312
Query: 360 ILD 362
+D
Sbjct: 313 PVD 315
Score = 70.1 bits (170), Expect = 9e-12
Identities = 40/112 (35%), Positives = 47/112 (41%), Gaps = 8/112 (7%)
Query: 255 WSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEG---MSVQKITCTSLCPVDGSW 311
WS W+ W+ C+V C G Q R R C G G +Q CP G W
Sbjct: 80 WSLWSTWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQCCPEMGGW 139
Query: 312 EVWSEWSVCSPECE---HLRIRECTAPPPRNGGKFCEGLSQESENC-TDGLC 359
W W CS C R R C P P+ GG C G +QESE C T +C
Sbjct: 140 SGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGG-HCPGQAQESEACDTQQVC 190
Score = 60.5 bits (145), Expect = 7e-09
Identities = 37/102 (36%), Positives = 44/102 (43%), Gaps = 16/102 (15%)
Query: 251 VNGGWSSWTEWSAC------NVRCGR--GWQKRSRTCTNPAPLNGGAFCEGMSVQKITCT 302
V+G W SW EWS C ++ C G Q R RTC G C G C
Sbjct: 314 VDGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRK--FDGHRCAGQQQDIRHCY 371
Query: 303 SL--CPVDGSWEVWSEWSVCSPEC----EHLRIRECTAPPPR 338
S+ CP+ GSW WS W +C P C R R CT P+
Sbjct: 372 SIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQRLCTPLLPK 413
>gi|223671861 complement factor properdin precursor [Homo sapiens]
Length = 469
Score = 94.4 bits (233), Expect = 5e-19
Identities = 44/114 (38%), Positives = 59/114 (51%), Gaps = 12/114 (10%)
Query: 253 GGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTS--LCPVDGS 310
GGWS W W C+V C +G + R R C +PAP GG C G + + C + +CP G+
Sbjct: 137 GGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGG-HCPGQAQESEACDTQQVCPTHGA 195
Query: 311 WEVWSEWSVCSPEC-------EHLRIRECTAPPP--RNGGKFCEGLSQESENCT 355
W W W+ CS C + R R+C+AP P + GK C GL+ E CT
Sbjct: 196 WATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCT 249
Score = 82.4 bits (202), Expect = 2e-15
Identities = 40/112 (35%), Positives = 52/112 (46%), Gaps = 15/112 (13%)
Query: 251 VNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSL--CPVD 308
V GGW W S C V CG G RTC +P P +GG FC G + + C + CPVD
Sbjct: 256 VAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCPVD 315
Query: 309 GSWEVWSEWSVC------SPECEHLRIRECTAPPPRNGGKFCEGLSQESENC 354
G W+ W EWS C S C+ + P ++ G+ C G + C
Sbjct: 316 GEWDSWGEWSPCIRRNMKSISCQEI-------PGQQSRGRTCRGRKFDGHRC 360
Score = 73.6 bits (179), Expect = 8e-13
Identities = 40/123 (32%), Positives = 59/123 (47%), Gaps = 12/123 (9%)
Query: 252 NGGWSSWTEWSACNVRCGRG----WQKRSRTCTNPAPLN--GGAFCEGMSVQKITCTSL- 304
+G W++W W+ C+ C G + RSR C+ P P G C G++ ++ CT L
Sbjct: 193 HGAWATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLP 252
Query: 305 -CPVDGSWEVWSEWSVCSPEC---EHLRIRECTAPPPRNGGKFCEGLSQESENCTDGL-C 359
CPV G W W S C C + + R C P P++GG FC G + + C + C
Sbjct: 253 PCPVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPC 312
Query: 360 ILD 362
+D
Sbjct: 313 PVD 315
Score = 70.1 bits (170), Expect = 9e-12
Identities = 40/112 (35%), Positives = 47/112 (41%), Gaps = 8/112 (7%)
Query: 255 WSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEG---MSVQKITCTSLCPVDGSW 311
WS W+ W+ C+V C G Q R R C G G +Q CP G W
Sbjct: 80 WSLWSTWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQCCPEMGGW 139
Query: 312 EVWSEWSVCSPECE---HLRIRECTAPPPRNGGKFCEGLSQESENC-TDGLC 359
W W CS C R R C P P+ GG C G +QESE C T +C
Sbjct: 140 SGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGG-HCPGQAQESEACDTQQVC 190
Score = 60.5 bits (145), Expect = 7e-09
Identities = 37/102 (36%), Positives = 44/102 (43%), Gaps = 16/102 (15%)
Query: 251 VNGGWSSWTEWSAC------NVRCGR--GWQKRSRTCTNPAPLNGGAFCEGMSVQKITCT 302
V+G W SW EWS C ++ C G Q R RTC G C G C
Sbjct: 314 VDGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRK--FDGHRCAGQQQDIRHCY 371
Query: 303 SL--CPVDGSWEVWSEWSVCSPEC----EHLRIRECTAPPPR 338
S+ CP+ GSW WS W +C P C R R CT P+
Sbjct: 372 SIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQRLCTPLLPK 413
>gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo
sapiens]
Length = 1386
Score = 86.7 bits (213), Expect = 1e-16
Identities = 67/222 (30%), Positives = 101/222 (45%), Gaps = 18/222 (8%)
Query: 38 NGEALPESIPSAPGT-------LPHFIEEPDDAYIIKSNPIALRCKA--RPAMQIFFKCN 88
N LP PS G+ +P +E+P D + + P L C+A RP I + N
Sbjct: 41 NHTLLPPGDPSLNGSRVGPEDAMPRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKN 100
Query: 89 GEWVHQ-NEHVSEETLDESSGLKVREVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKS 147
G V E L SG ++ R + P++ CVA ++LG + S
Sbjct: 101 GARVATVREDPRAHRLLLPSGALFFPRIVHGRRAR------PDEGVYTCVARNYLGAAAS 154
Query: 148 RKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDEN 207
R AS+ +A LR +F Q P V + VL C PP G P V W K+ + +++E
Sbjct: 155 RNASLEVAVLRDDFRQSPGNVVVAVGEPAVLECVPPRGHPEPSVSWRKDGARL--KEEEG 212
Query: 208 IDTRADHNLIIRQARLSDSGNYTCMAANIVAKRRSLSATVVV 249
T L++ SD+G Y C+A+N+ +R S +A V+V
Sbjct: 213 RITIRGGKLMMSHTLKSDAGMYVCVASNMAGERESAAAEVMV 254
Score = 44.3 bits (103), Expect = 6e-04
Identities = 34/116 (29%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 136 CVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEWLK 195
CVA + G +S A V + R +F + P + V + + C +G P + W K
Sbjct: 236 CVASNMAGERESAAAEVMVLE-RPSFLRRPVNQVVLADAPVTFLCEV-KGDPPPRLRWRK 293
Query: 196 NEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVAKRRSLSATVVVYV 251
+ + + + E R+DH+L I D G YTC+A N V R S ++ V+V
Sbjct: 294 EDGELPTGRYE---IRSDHSLWIGHVSAEDEGTYTCVAENSVG-RAEASGSLSVHV 345
Score = 37.0 bits (84), Expect = 0.088
Identities = 54/216 (25%), Positives = 78/216 (36%), Gaps = 38/216 (17%)
Query: 54 PHFIEEPDDAYIIKSNPIALRC--KARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKV 111
P + +P D +A +C K P IF++ G S+ L S L+
Sbjct: 347 PQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEG---------SQVLLFPSQSLQP 397
Query: 112 REVF-------INVTRQQVEDFHGPEDYWCQCV--AWSHLGTSKSRKASVRIAYLRKNFE 162
F +N+T Q D Y CQ V A S L + + L
Sbjct: 398 TGRFSVSPRGQLNITAVQRGD---AGYYVCQAVSVAGSILAKALLEIKGASLDGLPPVIL 454
Query: 163 QDPQGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQAR 222
Q P + + + + L CR G P V W K+ + + + D T A+ L I +
Sbjct: 455 QGPANQTLVLGSSVWLPCRVT-GNPQPSVRWKKDGQWLQGD-DLQFKTMANGTLYIANVQ 512
Query: 223 LSDSGNYTCMAANIVAKRRSLSATVVVYVNGGWSSW 258
D G Y+C VAK + AT WS W
Sbjct: 513 EMDMGFYSC-----VAKSSTGEAT--------WSGW 535
Score = 33.5 bits (75), Expect = 0.97
Identities = 29/87 (33%), Positives = 42/87 (48%), Gaps = 19/87 (21%)
Query: 178 LHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLII-------------RQARLS 224
L CR EG P +EW KN + + ++ D RA H L++ R+AR
Sbjct: 83 LPCRA-EGRPRPNIEWYKNGARVATVRE---DPRA-HRLLLPSGALFFPRIVHGRRAR-P 136
Query: 225 DSGNYTCMAANIVAKRRSLSATVVVYV 251
D G YTC+A N + S +A++ V V
Sbjct: 137 DEGVYTCVARNYLGAAASRNASLEVAV 163
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 85.9 bits (211), Expect = 2e-16
Identities = 45/116 (38%), Positives = 57/116 (49%), Gaps = 11/116 (9%)
Query: 251 VNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFC------EGMSVQKITCTS- 303
V GGW W+EW+ C+ C + RSR C P P +GGA C G Q+ C S
Sbjct: 3407 VPGGWCPWSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSY 3466
Query: 304 -LCPVDGSWEVWSEWSVCSPEC--EHLRIRECTAPPPRNGGKFCEGLSQESENCTD 356
CPVDG+W W WS C C + R R C+ PP GG+ C G +S C +
Sbjct: 3467 ATCPVDGAWGPWGPWSPCD-MCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQE 3521
Score = 83.6 bits (205), Expect = 8e-16
Identities = 41/115 (35%), Positives = 54/115 (46%), Gaps = 9/115 (7%)
Query: 252 NGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGM----SVQKITCTSLCPV 307
N W+SW W C+ CG G Q+R R P P GG +C + ++ CPV
Sbjct: 3946 NCSWTSWAPWEPCSRSCGVGQQRRLRAYRPPGP--GGHWCPNILTAYQERRFCNLRACPV 4003
Query: 308 DGSWEVWSEWSVCSPEC---EHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLC 359
G W WS WS C C + LR R C++PP +NGG C G ++ C C
Sbjct: 4004 PGGWSRWSPWSWCDRSCGGGQSLRSRSCSSPPSKNGGAPCAGERHQARLCNPMPC 4058
Score = 82.4 bits (202), Expect = 2e-15
Identities = 40/96 (41%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Query: 253 GGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITC-TSLCPVDGSW 311
G W W+ W C+ CG Q RSR C+ P L C G Q C T+ CPVDG W
Sbjct: 1695 GAWGPWSPWGPCSRTCGPWGQGRSRRCS-PLGLLVLQNCPGPEHQSQACFTAACPVDGEW 1753
Query: 312 EVWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGL 347
WS WSVCS C R+ P+NGG+ C L
Sbjct: 1754 STWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCAAL 1789
Score = 80.1 bits (196), Expect = 9e-15
Identities = 40/115 (34%), Positives = 58/115 (50%), Gaps = 15/115 (13%)
Query: 254 GWSSWTEWSACNVRC-----GRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTS-LCPV 307
GW+ WT WS+C+ C G GW+ RSR C +P G + C G + Q+ C+ +CPV
Sbjct: 2774 GWTPWTSWSSCSQSCLAPGGGPGWRSRSRLCPSP----GDSSCPGDATQEEPCSPPVCPV 2829
Query: 308 DGSWEVWSEWSVCSPECE---HLRIRECTAPPPRNGGKFCEGLSQESENCTDGLC 359
W +W+ WS CS C+ R R C++ P G C G ++ +C C
Sbjct: 2830 PSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAP--GDTTCPGPHSQTRDCNTQPC 2882
Score = 75.9 bits (185), Expect = 2e-13
Identities = 39/101 (38%), Positives = 50/101 (49%), Gaps = 6/101 (5%)
Query: 258 WTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITC-TSLCPVDGSWEVWSE 316
W+ WS+C+ CG G + + P PL GG+ C + +C CPV G+W +W
Sbjct: 2506 WSVWSSCSRSCGLGLTFQRQELLRP-PLPGGS-CPRDRFRSQSCFVQACPVAGAWAMWEA 2563
Query: 317 WSVCSPEC---EHLRIRECTAPPPRNGGKFCEGLSQESENC 354
W CS C R R C PPP+NGG C G SQE C
Sbjct: 2564 WGPCSVSCGGGHQSRQRSCVDPPPKNGGAPCPGASQERAPC 2604
Score = 72.4 bits (176), Expect = 2e-12
Identities = 38/115 (33%), Positives = 55/115 (47%), Gaps = 13/115 (11%)
Query: 254 GWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSLCPVD-GSWE 312
GWS+W+ W+ C+ CG G + R R+ +NP GGA CEG + C ++C + W
Sbjct: 2717 GWSAWSSWAPCDRSCGSGVRARFRSPSNPPAAWGGAPCEGDRQELQGCHTVCGTEVFGWT 2776
Query: 313 VWSEWSVCSPEC--------EHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLC 359
W+ WS CS C R R C +P G C G + + E C+ +C
Sbjct: 2777 PWTSWSSCSQSCLAPGGGPGWRSRSRLCPSP----GDSSCPGDATQEEPCSPPVC 2827
Score = 70.5 bits (171), Expect = 7e-12
Identities = 38/116 (32%), Positives = 44/116 (37%), Gaps = 16/116 (13%)
Query: 255 WSSWTEWSACNVRCGRGWQKRSRTCTN------------PAPLNGGAFCEGMSVQKITC- 301
WS WT WS C+ CG R R C P P C G ++ C
Sbjct: 3186 WSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPCL 3245
Query: 302 TSLCPVDGSWEVWSEWSVCSPECE---HLRIRECTAPPPRNGGKFCEGLSQESENC 354
C G W W WS CS C R R C PPP+ G +CEG + E C
Sbjct: 3246 LQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRAQGEVC 3301
Score = 66.6 bits (161), Expect = 1e-10
Identities = 42/124 (33%), Positives = 55/124 (44%), Gaps = 9/124 (7%)
Query: 251 VNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSLCPVDGS 310
V G W+ W W C+V CG G Q R R+C +P P NGGA C G S ++ C L P G
Sbjct: 2554 VAGAWAMWEAWGPCSVSCGGGHQSRQRSCVDPPPKNGGAPCPGASQERAPC-GLQPCSGG 2612
Query: 311 WEV-WSEWSVCSPECEHLRIRECTAPP---PRNGGKFCEGLSQESENCTDGLCILDKK-- 364
+ V + C+ + C PP + C G E C GL + D +
Sbjct: 2613 TDCELGRVYVSADLCQKGLVPPC--PPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCL 2670
Query: 365 PLHE 368
PL E
Sbjct: 2671 PLSE 2674
Score = 66.2 bits (160), Expect = 1e-10
Identities = 36/104 (34%), Positives = 46/104 (44%), Gaps = 7/104 (6%)
Query: 221 ARLSDSGNYTCMAANIVAKRRSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQKRSRTCT 280
ARL N TC++ + GWS WT WS C+ C G ++R R T
Sbjct: 2960 ARLDSCNNCTCVSGKMACTSERCPVAC------GWSPWTLWSLCSCSCNVGIRRRFRAGT 3013
Query: 281 NPAPLNGGAFCEGMSVQKITCTSLCPVDGSWEVWSEWSVCSPEC 324
P GGA C+G +++ C SL P G W WS CS C
Sbjct: 3014 APPAAFGGAECQGPTMEAEFC-SLRPCPGPGGEWGPWSPCSVPC 3056
Score = 64.7 bits (156), Expect = 4e-10
Identities = 30/74 (40%), Positives = 38/74 (51%), Gaps = 2/74 (2%)
Query: 253 GGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSL-CPVDGSW 311
GGW W WS C+ CG G + R+R C P P G +CEG Q C +L CPV
Sbjct: 3253 GGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPVTNCT 3312
Query: 312 EV-WSEWSVCSPEC 324
+ +E+S C P C
Sbjct: 3313 AIEGAEYSPCGPPC 3326
Score = 60.8 bits (146), Expect = 6e-09
Identities = 41/141 (29%), Positives = 55/141 (39%), Gaps = 14/141 (9%)
Query: 218 IRQARLSDSGNYTCMAANIVAKRRSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQKRSR 277
+R R G + C + R V GGWS W+ WS C+ CG G RSR
Sbjct: 3970 LRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLRSR 4029
Query: 278 TCTNPAPLNGGAFCEGMSVQKITCTSLCPVDGSWEVWSEWSVCSPECEHLRIRECTAPPP 337
+C++P NGGA C G Q C + P + E C+ C P
Sbjct: 4030 SCSSPPSKNGGAPCAGERHQARLCNPM-PCEAGCPAGMEVVTCANRC------------P 4076
Query: 338 RNGGKFCEGL-SQESENCTDG 357
R EG+ Q+ + C G
Sbjct: 4077 RRCSDLQEGIVCQDDQVCQKG 4097
Score = 55.1 bits (131), Expect = 3e-07
Identities = 25/58 (43%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 298 KITCTSL-CPVDGSWEVWSEWSVCSPECE---HLRIRECTAPPPRNGGKFCEGLSQES 351
++ CT L CPV G W WSEW++CS C R R C P P++GG C G + E+
Sbjct: 3397 RLNCTDLPCPVPGGWCPWSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEA 3454
Score = 54.7 bits (130), Expect = 4e-07
Identities = 49/182 (26%), Positives = 70/182 (38%), Gaps = 38/182 (20%)
Query: 220 QARLSDSGNYTCMAANIVAKRRSLSATVVVYVNGGWSSWTEWSACNVRC-GRGWQKRSRT 278
Q + GN +C + S S +GG+ W+ W C+ C G G + RSR
Sbjct: 3784 QTLRTSCGNCSCAHGKL-----SCSLDDCFEADGGFGPWSPWGPCSRSCGGLGTRTRSRQ 3838
Query: 279 CTNPAPLNGGAFCEGMSVQKITCTSL-CP------------VDGSWEVWSEWSVCSPECE 325
C P G C G Q + C S CP + G W WS WS CS C
Sbjct: 3839 CVLTMPTLSGQGCRGPR-QDLECPSPDCPGAEGSTVEPVTGLPGGWGPWSSWSPCSRSC- 3896
Query: 326 HLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILDKKPLHEIKPQSIENASDIALYSG 385
+ P R+ + C NCT G PL E +P ++ + +++ + G
Sbjct: 3897 ----TDPARPAWRSRTRLC------LANCTMG------DPLQE-RPCNLPSCTELPVCPG 3939
Query: 386 LG 387
G
Sbjct: 3940 PG 3941
Score = 53.5 bits (127), Expect = 9e-07
Identities = 27/62 (43%), Positives = 34/62 (54%), Gaps = 4/62 (6%)
Query: 298 KITCTS-LCPVDGSWEVWSEWSVCSPECE---HLRIRECTAPPPRNGGKFCEGLSQESEN 353
K+ CTS CPV W W+ WS+CS C R R TAPP GG C+G + E+E
Sbjct: 2974 KMACTSERCPVACGWSPWTLWSLCSCSCNVGIRRRFRAGTAPPAAFGGAECQGPTMEAEF 3033
Query: 354 CT 355
C+
Sbjct: 3034 CS 3035
Score = 52.8 bits (125), Expect = 2e-06
Identities = 34/121 (28%), Positives = 46/121 (38%), Gaps = 14/121 (11%)
Query: 253 GGWSSWTEWSACNVRC----GRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSLCPVD 308
GGW W+ WS C+ C W+ R+R C + ++ T +CP
Sbjct: 3881 GGWGPWSSWSPCSRSCTDPARPAWRSRTRLCLANCTMGDPLQERPCNLPSCTELPVCPGP 3940
Query: 309 G------SWEVWSEWSVCSPECEHLRIRECTA-PPPRNGGKFCEGL---SQESENCTDGL 358
G SW W+ W CS C + R A PP GG +C + QE C
Sbjct: 3941 GCGAGNCSWTSWAPWEPCSRSCGVGQQRRLRAYRPPGPGGHWCPNILTAYQERRFCNLRA 4000
Query: 359 C 359
C
Sbjct: 4001 C 4001
Score = 50.1 bits (118), Expect = 1e-05
Identities = 27/72 (37%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
Query: 255 WSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSLCPVDGSWEV- 313
W+ W+ WS C V CG G Q R+R C AP + C G Q T P G E
Sbjct: 4256 WTLWSSWSDCPVSCGGGNQVRTRACRAAAPHHRSPPCLGPDTQ----TRQQPCPGLLEAC 4311
Query: 314 -WSEWSVCSPEC 324
W W CS C
Sbjct: 4312 SWGPWGPCSRSC 4323
Score = 49.7 bits (117), Expect = 1e-05
Identities = 34/111 (30%), Positives = 44/111 (39%), Gaps = 23/111 (20%)
Query: 253 GGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSL------CP 306
G WSSW W C+V CG G Q RSR C P C G + Q TC++ CP
Sbjct: 3646 GVWSSWGPWEDCSVSCGGGEQLRSRRCARPP-------CPGPARQSRTCSTQVCREAGCP 3698
Query: 307 VDGSWEVWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDG 357
+ C C H+ + G F EG +E +C +G
Sbjct: 3699 AGRLYRECQPGEGCPFSCAHV---------TQQVGCFSEG-CEEGCHCPEG 3739
Score = 49.3 bits (116), Expect = 2e-05
Identities = 37/134 (27%), Positives = 51/134 (38%), Gaps = 43/134 (32%)
Query: 255 WSSWTEWSACNVRCG-RGWQKRSRTCTN---------------PAPLN------------ 286
WS W+ WS C+ CG RG Q R R+ T+ P P
Sbjct: 4162 WSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQSQSQPCPQPSCPPLCLQGTRS 4221
Query: 287 ---GGAFCEGMSVQKITCT--------SLCPVDGSWEVWSEWSVCSPEC---EHLRIREC 332
G ++ +G Q+ +CT + C V +W +WS WS C C +R R C
Sbjct: 4222 RTLGDSWLQG-ECQRCSCTPEGVICEDTECAVPEAWTLWSSWSDCPVSCGGGNQVRTRAC 4280
Query: 333 TAPPPRNGGKFCEG 346
A P + C G
Sbjct: 4281 RAAAPHHRSPPCLG 4294
Score = 46.6 bits (109), Expect = 1e-04
Identities = 25/66 (37%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
Query: 246 TVVVYVNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGM--SVQKITCTS 303
T V+G WS+W+ WS C+ C RG R R C +P NGG C + + T
Sbjct: 1744 TAACPVDGEWSTWSPWSVCSEPC-RGTMTRQRQCHSPQ--NGGRTCAALPGGLHSTRQTK 1800
Query: 304 LCPVDG 309
CP DG
Sbjct: 1801 PCPQDG 1806
Score = 45.4 bits (106), Expect = 2e-04
Identities = 21/58 (36%), Positives = 26/58 (44%), Gaps = 10/58 (17%)
Query: 305 CPVDGSWEVWSEWSVCSPEC---EHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLC 359
CP G W W W CS C E LR R C PP C G +++S C+ +C
Sbjct: 3642 CPDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPP-------CPGPARQSRTCSTQVC 3692
Score = 44.3 bits (103), Expect = 6e-04
Identities = 28/112 (25%), Positives = 38/112 (33%), Gaps = 13/112 (11%)
Query: 254 GWSSWTEWSACNVRCGRGW--QKRSRTCTNPAPLNGGAFCEGMSVQKITCTSLCPVDGSW 311
GW W C V R W Q+ C C+ ++ C VD W
Sbjct: 1860 GWCVWPRQCPCLVDGARYWPGQRIKADCQL-------CICQDGRPRRCRLNPDCAVDCGW 1912
Query: 312 EVWSEWSVCSPECEHLRI----RECTAPPPRNGGKFCEGLSQESENCTDGLC 359
WS W+ C C I R P P G+ C G+ +++ C C
Sbjct: 1913 SSWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEPC 1964
Score = 44.3 bits (103), Expect = 6e-04
Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 3/53 (5%)
Query: 305 CPVDGSWEVWSEWSVCSPEC---EHLRIRECTAPPPRNGGKFCEGLSQESENC 354
CP+ W WS W+ C C R R + PP GG CEG QE + C
Sbjct: 2712 CPLPCGWSAWSSWAPCDRSCGSGVRARFRSPSNPPAAWGGAPCEGDRQELQGC 2764
Score = 42.7 bits (99), Expect = 0.002
Identities = 36/144 (25%), Positives = 50/144 (34%), Gaps = 37/144 (25%)
Query: 255 WSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQ-----KITCTSLCPVD- 308
W W WS C+ C G Q R R+C++ AP G C G Q CT+ CP +
Sbjct: 2833 WGLWAPWSTCSAPCDGGIQTRGRSCSSLAP--GDTTCPGPHSQTRDCNTQPCTAQCPENM 2890
Query: 309 ---GSWEVWSEWSVC---------SPECEHLRIRECTAPP----------PR-------N 339
+ + E C EC CT PP PR +
Sbjct: 2891 LFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLH 2950
Query: 340 GGKFCEGLSQESENCTDGLCILDK 363
G + G ++C + C+ K
Sbjct: 2951 GQLYASGAMARLDSCNNCTCVSGK 2974
Score = 42.0 bits (97), Expect = 0.003
Identities = 46/170 (27%), Positives = 64/170 (37%), Gaps = 15/170 (8%)
Query: 180 CRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVAK 239
CRP P ++ PI S + A L QA D N TC+ ++V
Sbjct: 4700 CRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCP 4759
Query: 240 RRSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKI 299
+ V G WS+W S+C+ CG G +R RTC G A C+ ++
Sbjct: 4760 HQECP------VLGPWSAW---SSCSAPCGGGTMERHRTCEGGP---GVAPCQAQDTEQR 4807
Query: 300 TCTSL--CPVDGSWEVWSEWSV-CSPECEHLRIRECTAPPPRNGGKFCEG 346
+L CP +V S + C C HL+ P G C G
Sbjct: 4808 QECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPG 4857
Score = 38.9 bits (89), Expect = 0.023
Identities = 19/52 (36%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Query: 251 VNGGWSSWTEWSACNVRCG-RGWQKRSRTCTNPAPLNGGAFCEGMSVQKITC 301
V+ GWSSW+ W+ C CG + Q R+ NP P G C G+ + C
Sbjct: 1908 VDCGWSSWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRC 1959
Score = 38.5 bits (88), Expect = 0.030
Identities = 33/96 (34%), Positives = 37/96 (38%), Gaps = 14/96 (14%)
Query: 273 QKRSRTCTNPA---PLNGGA-FCEGMSVQKITCTS--LCPVDGSWEVWSEWSVCSPECE- 325
Q R R C +PA P G C Q+ C CP W +W WS C C
Sbjct: 4574 QHRHRLCLDPATGRPWTGAPHLCTAPLSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSG 4633
Query: 326 --HLRIRECTAPPPRNGGKFCEGLSQESENCTDGLC 359
LR RE A GG E +QES C G C
Sbjct: 4634 GFRLRWREAEA---LCGGGCREPWAQES--CNGGPC 4664
Score = 38.1 bits (87), Expect = 0.039
Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 8/70 (11%)
Query: 257 SWTEWSACNVRCGRGWQKRSRTC----TNPAPLNGGAFCEGMSVQKITCTS-LCPVDGSW 311
SW W C+ CG G RS +C P F + + C S CP + W
Sbjct: 4312 SWGPWGPCSRSCGPGLASRSGSCPCLMAKADPTCNSTF---LHLDTQGCYSGPCPEECVW 4368
Query: 312 EVWSEWSVCS 321
WS W+ CS
Sbjct: 4369 SSWSSWTRCS 4378
Score = 33.5 bits (75), Expect = 0.97
Identities = 27/96 (28%), Positives = 34/96 (35%), Gaps = 19/96 (19%)
Query: 255 WSSWTEWSACNVRCGRGWQKRSRT--------CTNP---APLNGGAF--CEGM-SVQKIT 300
WS W WS C V C G++ R R C P NGG CE +V +
Sbjct: 4618 WSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCPECEAQDTVFTLD 4677
Query: 301 CTSLCPVDGSWEVWSEWSVCSPECEHLRIRECTAPP 336
C + CP ++W C C PP
Sbjct: 4678 CANQCP-HSCADLWDRVQCLQGPCR----PGCRCPP 4708
Score = 32.7 bits (73), Expect = 1.7
Identities = 32/109 (29%), Positives = 45/109 (41%), Gaps = 13/109 (11%)
Query: 255 WSSWTEWSACNVRCGRGWQKRSRTCTNPAP--LNGGAFCEGMSVQKITC-TSLCPVDGSW 311
WSSW+ W+ C+ C Q+R R PA GA C + C S C D
Sbjct: 4368 WSSWSSWTRCS--CRVLVQQRYRH-QGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCT 4424
Query: 312 EVWSEWSVCSPEC-----EHLRIRECTAPPPRNGGKFC-EGLSQESENC 354
+ E+ C C HL + C PP G +C +GL +++ C
Sbjct: 4425 PPF-EFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGC 4472
Score = 32.0 bits (71), Expect = 2.8
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 3/59 (5%)
Query: 253 GGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSLCPVDGSW 311
G W WS C+V CG G+ R+RT + L + C G+ +CP D W
Sbjct: 3041 GPGGEWGPWSPCSVPCGGGY--RNRTRGSSRSLMEFSTC-GLQPCAGPVPGMCPRDKQW 3096
>gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens]
Length = 1585
Score = 84.3 bits (207), Expect = 5e-16
Identities = 41/105 (39%), Positives = 59/105 (56%), Gaps = 6/105 (5%)
Query: 258 WTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITC--TSLCPVDGSWEVWS 315
W+ WS C++ CG+G Q R+R+C + +P G C G + C ++ CPV G WE W
Sbjct: 315 WSPWSVCSLTCGQGLQVRTRSCVS-SPY--GTLCSGPLRETRPCNNSATCPVHGVWEEWG 371
Query: 316 EWSVCSPEC-EHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLC 359
WS+CS C R R T PP++GGK CEG +++ C+ C
Sbjct: 372 SWSLCSRSCGRGSRSRMRTCVPPQHGGKACEGPELQTKLCSMAAC 416
Score = 84.3 bits (207), Expect = 5e-16
Identities = 44/138 (31%), Positives = 65/138 (47%), Gaps = 8/138 (5%)
Query: 226 SGNYTCMAANIVAKRRSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPL 285
S Y + + + + R + + V+G W W WS C+ CGRG + R RTC P
Sbjct: 338 SSPYGTLCSGPLRETRPCNNSATCPVHGVWEEWGSWSLCSRSCGRGSRSRMRTCV--PPQ 395
Query: 286 NGGAFCEGMSVQKITCT-SLCPVDGSWEVWSEWSVCSPECEH---LRIRECTAPPPRNGG 341
+GG CEG +Q C+ + CPV+G W W W CS C + R R+C+ P
Sbjct: 396 HGGKACEGPELQTKLCSMAACPVEGQWLEWGPWGPCSTSCANGTQQRSRKCSVAGP--AW 453
Query: 342 KFCEGLSQESENCTDGLC 359
C G ++ C++ C
Sbjct: 454 ATCTGALTDTRECSNLEC 471
Score = 75.1 bits (183), Expect = 3e-13
Identities = 45/138 (32%), Positives = 61/138 (44%), Gaps = 12/138 (8%)
Query: 227 GNYTCMAANIVAKRRSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLN 286
G C + K S++A V G W W W C+ C G Q+RSR C+ P
Sbjct: 397 GGKACEGPELQTKLCSMAACPV---EGQWLEWGPWGPCSTSCANGTQQRSRKCSVAGP-- 451
Query: 287 GGAFCEGMSVQKITCTSL-CPV-DGSWEVWSEWSVCSPECE---HLRIRECTAPPPRNGG 341
A C G C++L CP D W W+ WS+CS C+ R R C A + G
Sbjct: 452 AWATCTGALTDTRECSNLECPATDSKWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQ--G 509
Query: 342 KFCEGLSQESENCTDGLC 359
CEG +E + C++ C
Sbjct: 510 YPCEGTGEEVKPCSEKRC 527
Score = 42.0 bits (97), Expect = 0.003
Identities = 25/89 (28%), Positives = 33/89 (37%), Gaps = 3/89 (3%)
Query: 219 RQARLSDSGNYTCMAANIVAKRRSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQKRSRT 278
R + S +G + R S + W W WS C+ C GWQ+R R
Sbjct: 442 RSRKCSVAGPAWATCTGALTDTRECSNLECPATDSKWGPWNAWSLCSKTCDTGWQRRFRM 501
Query: 279 CTNPAPLNGGAFCEGMSVQKITCT-SLCP 306
C A G CEG + C+ CP
Sbjct: 502 C--QATGTQGYPCEGTGEEVKPCSEKRCP 528
Score = 35.0 bits (79), Expect = 0.33
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 6/52 (11%)
Query: 308 DGSWEVWSEWSVCSPECE---HLRIRECTAPPPRNGGKFCEGLSQESENCTD 356
D + E WS WSVCS C +R R C + P G C G +E+ C +
Sbjct: 309 DPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSP---YGTLCSGPLRETRPCNN 357
>gi|17511435 roundabout homolog 4, magic roundabout [Homo sapiens]
Length = 1007
Score = 69.7 bits (169), Expect = 1e-11
Identities = 45/152 (29%), Positives = 71/152 (46%), Gaps = 8/152 (5%)
Query: 136 CVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEWLK 195
C A + LGT+ SR A + +A LR++F+ P+ + L C PP G P V W K
Sbjct: 114 CEASNRLGTAVSRGARLSVAVLREDFQIQPRDMVAVVGEQFTLECGPPWGHPEPTVSWWK 173
Query: 196 NEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVAKRRSLSATVVVYVNGGW 255
+ +P+ + + T + +L++ +A SD G Y C+A N R S +A V + +
Sbjct: 174 DGKPLALQPGRH--TVSGGSLLMARAEKSDEGTYMCVATNSAGHRESRAARVSIQEPQDY 231
Query: 256 SSWTEWSACNVRCGRGWQKRSRTCTNPAPLNG 287
+ E A + Q + T NP P G
Sbjct: 232 TEPVELLAVRI------QLENVTLLNPDPAEG 257
>gi|116875765 tight junction protein 1 isoform b [Homo sapiens]
Length = 1668
Score = 65.5 bits (158), Expect = 2e-10
Identities = 36/81 (44%), Positives = 43/81 (53%), Gaps = 3/81 (3%)
Query: 546 GVFGHLGGRLVMPNTGVSLLIPHGAIPEENSWEIYMSI---NQGEPSLQSDGSEVLLSPE 602
G+F GG L TGVS++IP GAIPE EIY + N P L + E LLSP
Sbjct: 1558 GIFNSNGGVLSSIETGVSIIIPQGAIPEGVEQEIYFKVCRDNSILPPLDKEKGETLLSPL 1617
Query: 603 VTCGPPDMIVTTPFALTIPHC 623
V CGP + P L +PHC
Sbjct: 1618 VMCGPHGLKFLKPVELRLPHC 1638
>gi|116875767 tight junction protein 1 isoform a [Homo sapiens]
Length = 1748
Score = 65.5 bits (158), Expect = 2e-10
Identities = 36/81 (44%), Positives = 43/81 (53%), Gaps = 3/81 (3%)
Query: 546 GVFGHLGGRLVMPNTGVSLLIPHGAIPEENSWEIYMSI---NQGEPSLQSDGSEVLLSPE 602
G+F GG L TGVS++IP GAIPE EIY + N P L + E LLSP
Sbjct: 1638 GIFNSNGGVLSSIETGVSIIIPQGAIPEGVEQEIYFKVCRDNSILPPLDKEKGETLLSPL 1697
Query: 603 VTCGPPDMIVTTPFALTIPHC 623
V CGP + P L +PHC
Sbjct: 1698 VMCGPHGLKFLKPVELRLPHC 1718
>gi|110735441 ADAM metallopeptidase with thrombospondin type 1
motif, 16 preproprotein [Homo sapiens]
Length = 1224
Score = 65.1 bits (157), Expect = 3e-10
Identities = 29/58 (50%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Query: 252 NGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTS-LCPVD 308
+G WS W+ WS C+ CG G RSR CTNP P +GG FCEG + C S CP D
Sbjct: 586 HGHWSDWSSWSPCSRTCGGGVSHRSRLCTNPKPSHGGKFCEGSTRTLKLCNSQKCPRD 643
Score = 55.5 bits (132), Expect = 2e-07
Identities = 30/77 (38%), Positives = 35/77 (45%), Gaps = 5/77 (6%)
Query: 290 FCEGMSVQKITCTSLCPVDGSWEVWSEWSVCSPEC----EHLRIRECTAPPPRNGGKFCE 345
+C G K P G W WS WS CS C H R R CT P P +GGKFCE
Sbjct: 568 WCRGGQCVKYGDEGPKPTHGHWSDWSSWSPCSRTCGGGVSH-RSRLCTNPKPSHGGKFCE 626
Query: 346 GLSQESENCTDGLCILD 362
G ++ + C C D
Sbjct: 627 GSTRTLKLCNSQKCPRD 643
Score = 39.3 bits (90), Expect = 0.018
Identities = 29/81 (35%), Positives = 37/81 (45%), Gaps = 12/81 (14%)
Query: 255 WSSWTEWSACNVRCGRGWQKRSRTC--TNP---APLNGGAFCEGMSVQKITCTSLC---- 305
WS+ W+ C+ CG+GW+KR+ C TNP A L A C ++ L
Sbjct: 990 WSAGP-WAECSHTCGKGWRKRAVACKSTNPSARAQLLPDAVCTSEPKPRMHEACLLQRCH 1048
Query: 306 -PVDGSWEVWSEWSVCSPECE 325
P W V S WS CS CE
Sbjct: 1049 KPKKLQWLV-SAWSQCSVTCE 1068
Score = 35.0 bits (79), Expect = 0.33
Identities = 36/139 (25%), Positives = 53/139 (38%), Gaps = 19/139 (13%)
Query: 239 KRRSLSATVVVYVNGGWSSWT--EWSACNVRCGRGWQKRSRTCT-----NPAPLNGGAFC 291
K R ++ V V+ SW+ WSAC+ CG G Q R CT + P+
Sbjct: 912 KTRPVTGLVPCKVSACPPSWSVGNWSACSRTCGGGAQSRPVQCTRRVHYDSEPVPASLCP 971
Query: 292 EGMSVQKITCTS-LCPVDGSWEVWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQE 350
+ + C S CP S W+E S + R C + P S
Sbjct: 972 QPAPSSRQACNSQSCPPAWSAGPWAECSHTCGKGWRKRAVACKSTNP----------SAR 1021
Query: 351 SENCTDGLCILDKKP-LHE 368
++ D +C + KP +HE
Sbjct: 1022 AQLLPDAVCTSEPKPRMHE 1040
Score = 32.3 bits (72), Expect = 2.2
Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 9/82 (10%)
Query: 253 GGWSSWTEWSACNVRCGRGWQKRSRTC-TNPAPLNGGAFCEGMSVQKITCTSLCPV---- 307
G W + + WS C CG G Q RS C P +G + S T CP+
Sbjct: 1128 GSWFA-SPWSQCTASCGGGVQTRSVQCLAGGRPASGCLLHQKPSASLACNTHFCPIAEKK 1186
Query: 308 DGSWEVWSEWSVCSPE---CEH 326
D + + W P+ C H
Sbjct: 1187 DAFCKDYFHWCYLVPQHGMCSH 1208
>gi|189242612 complement component 6 precursor [Homo sapiens]
Length = 934
Score = 64.7 bits (156), Expect = 4e-10
Identities = 30/76 (39%), Positives = 39/76 (51%), Gaps = 7/76 (9%)
Query: 307 VDGSWEVWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDGL-------C 359
VDG W WS WS C + R REC P P+ GGK CEG ++ E+CT + C
Sbjct: 564 VDGQWGCWSSWSTCDATYKRSRTRECNNPAPQRGGKRCEGEKRQEEDCTFSIMENNGQPC 623
Query: 360 ILDKKPLHEIKPQSIE 375
I D + + E+ IE
Sbjct: 624 INDDEEMKEVDLPEIE 639
Score = 51.6 bits (122), Expect = 3e-06
Identities = 23/52 (44%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
Query: 251 VNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCT 302
V+G W W+ WS C+ R R+R C NPAP GG CEG Q+ CT
Sbjct: 564 VDGQWGCWSSWSTCDATYKRS---RTRECNNPAPQRGGKRCEGEKRQEEDCT 612
Score = 38.5 bits (88), Expect = 0.030
Identities = 35/129 (27%), Positives = 51/129 (39%), Gaps = 23/129 (17%)
Query: 257 SWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKIT--CT-SLCPVDGSWEV 313
+WT+W++C+ C G Q R R FCE + ++ T C CP++
Sbjct: 28 AWTQWTSCSKTCNSGTQSRHRQIVVDKYYQEN-FCEQICSKQETRECNWQRCPINCLLGD 86
Query: 314 WSEWSVCSPECE-HLRIRE-----------CTAP----PPRNGGKFCEGLSQESEN---C 354
+ WS C P E ++R CTAP P K C+ + +N C
Sbjct: 87 FGPWSDCDPCIEKQSKVRSVLRPSQFGGQPCTAPLVAFQPCIPSKLCKIEEADCKNKFRC 146
Query: 355 TDGLCILDK 363
G CI K
Sbjct: 147 DSGRCIARK 155
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,852,562
Number of Sequences: 37866
Number of extensions: 1985786
Number of successful extensions: 7268
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 126
Number of HSP's successfully gapped in prelim test: 164
Number of HSP's that attempted gapping in prelim test: 5476
Number of HSP's gapped (non-prelim): 1518
length of query: 953
length of database: 18,247,518
effective HSP length: 112
effective length of query: 841
effective length of database: 14,006,526
effective search space: 11779488366
effective search space used: 11779488366
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.