Guide to the Human Genome
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Search of human proteins with 209529726

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|209529726 PHD finger protein 21B isoform 2 [Homo sapiens]
         (489 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|209529726 PHD finger protein 21B isoform 2 [Homo sapiens]          973   0.0  
gi|19923937 PHD finger protein 21B isoform 1 [Homo sapiens]           953   0.0  
gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens]            295   8e-80
gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens]            275   9e-74
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa...    70   3e-12
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ...    70   4e-12
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ...    70   4e-12
gi|158420731 chromodomain helicase DNA binding protein 3 isoform...    70   4e-12
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa...    70   6e-12
gi|4557293 autoimmune regulator isoform 2 [Homo sapiens]               62   1e-09
gi|75677357 PHD finger protein 12 isoform 1 [Homo sapiens]             61   3e-09
gi|30842829 PHD finger protein 12 isoform 2 [Homo sapiens]             61   3e-09
gi|4557291 autoimmune regulator isoform 1 [Homo sapiens]               60   4e-09
gi|38788260 bromodomain PHD finger transcription factor isoform ...    59   1e-08
gi|38788274 bromodomain PHD finger transcription factor isoform ...    59   1e-08
gi|47419911 transcriptional intermediary factor 1 alpha isoform ...    59   1e-08
gi|47419909 transcriptional intermediary factor 1 alpha isoform ...    59   1e-08
gi|74027251 tripartite motif-containing 33 protein isoform beta ...    55   1e-07
gi|74027249 tripartite motif-containing 33 protein isoform alpha...    55   1e-07
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         53   7e-07
gi|38788333 remodeling and spacing factor 1 [Homo sapiens]             52   9e-07
gi|209977097 tripartite motif-containing 66 [Homo sapiens]             52   1e-06
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]             52   1e-06
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo...    52   2e-06
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo...    52   2e-06
gi|50345997 E1A binding protein p300 [Homo sapiens]                    51   2e-06
gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [H...    51   3e-06
gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [H...    51   3e-06
gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo sa...    49   8e-06
gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo sa...    49   8e-06

>gi|209529726 PHD finger protein 21B isoform 2 [Homo sapiens]
          Length = 489

 Score =  973 bits (2516), Expect = 0.0
 Identities = 489/489 (100%), Positives = 489/489 (100%)

Query: 1   MELQSRPEALAVELARHQNGDLKKQLHERQPRIAALSDKQALGTITAVPVTGPQVSSLQR 60
           MELQSRPEALAVELARHQNGDLKKQLHERQPRIAALSDKQALGTITAVPVTGPQVSSLQR
Sbjct: 1   MELQSRPEALAVELARHQNGDLKKQLHERQPRIAALSDKQALGTITAVPVTGPQVSSLQR 60

Query: 61  LAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPPKQPPTFQKATVVSVKNPSPALPTANNTV 120
           LAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPPKQPPTFQKATVVSVKNPSPALPTANNTV
Sbjct: 61  LAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPPKQPPTFQKATVVSVKNPSPALPTANNTV 120

Query: 121 SHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSNAAAMAPSTAVSVVSDSIKVQP 180
           SHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSNAAAMAPSTAVSVVSDSIKVQP
Sbjct: 121 SHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSNAAAMAPSTAVSVVSDSIKVQP 180

Query: 181 LLISADNKVIIIQPQVQTQPESTAESRPPTEEPSQGAQATKKKKEDRPPTQENPEKIAFM 240
           LLISADNKVIIIQPQVQTQPESTAESRPPTEEPSQGAQATKKKKEDRPPTQENPEKIAFM
Sbjct: 181 LLISADNKVIIIQPQVQTQPESTAESRPPTEEPSQGAQATKKKKEDRPPTQENPEKIAFM 240

Query: 241 VALGLVTTEHLEEIQSKRQERKRRSTANPAYSGLLETERKRLASNYLNNPLFLTARANED 300
           VALGLVTTEHLEEIQSKRQERKRRSTANPAYSGLLETERKRLASNYLNNPLFLTARANED
Sbjct: 241 VALGLVTTEHLEEIQSKRQERKRRSTANPAYSGLLETERKRLASNYLNNPLFLTARANED 300

Query: 301 PCWKNEITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALK 360
           PCWKNEITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALK
Sbjct: 301 PCWKNEITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALK 360

Query: 361 KDEGVPWTGMLAIVHSYVTHKTVKEEEKQKLLQRGSELQNEHQQLEERDRRLASAVQKCL 420
           KDEGVPWTGMLAIVHSYVTHKTVKEEEKQKLLQRGSELQNEHQQLEERDRRLASAVQKCL
Sbjct: 361 KDEGVPWTGMLAIVHSYVTHKTVKEEEKQKLLQRGSELQNEHQQLEERDRRLASAVQKCL 420

Query: 421 ELKTSLLARQRGTQSSLDRLRALLRLIQGEQLLQVTMTTTSPAPLLAGPWTKPSVAATHP 480
           ELKTSLLARQRGTQSSLDRLRALLRLIQGEQLLQVTMTTTSPAPLLAGPWTKPSVAATHP
Sbjct: 421 ELKTSLLARQRGTQSSLDRLRALLRLIQGEQLLQVTMTTTSPAPLLAGPWTKPSVAATHP 480

Query: 481 TVQHPQGHN 489
           TVQHPQGHN
Sbjct: 481 TVQHPQGHN 489


>gi|19923937 PHD finger protein 21B isoform 1 [Homo sapiens]
          Length = 531

 Score =  953 bits (2463), Expect = 0.0
 Identities = 489/531 (92%), Positives = 489/531 (92%), Gaps = 42/531 (7%)

Query: 1   MELQSRPEALAVELARHQNGDLKKQLHERQPRIAALSDKQALGTITAVPVTGPQVSSLQR 60
           MELQSRPEALAVELARHQNGDLKKQLHERQPRIAALSDKQALGTITAVPVTGPQVSSLQR
Sbjct: 1   MELQSRPEALAVELARHQNGDLKKQLHERQPRIAALSDKQALGTITAVPVTGPQVSSLQR 60

Query: 61  LAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPPKQPPTFQKATVVSVKNPSPALPTANNTV 120
           LAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPPKQPPTFQKATVVSVKNPSPALPTANNTV
Sbjct: 61  LAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPPKQPPTFQKATVVSVKNPSPALPTANNTV 120

Query: 121 SHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSNAAAMAPSTAVSVVSDSIKVQP 180
           SHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSNAAAMAPSTAVSVVSDSIKVQP
Sbjct: 121 SHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSNAAAMAPSTAVSVVSDSIKVQP 180

Query: 181 LLISADNK------------------------------------------VIIIQPQVQT 198
           LLISADNK                                          VIIIQPQVQT
Sbjct: 181 LLISADNKPPPRLLSSPHPATHHCPLHPSSLPLTPPSPSLSPSPLHGIFQVIIIQPQVQT 240

Query: 199 QPESTAESRPPTEEPSQGAQATKKKKEDRPPTQENPEKIAFMVALGLVTTEHLEEIQSKR 258
           QPESTAESRPPTEEPSQGAQATKKKKEDRPPTQENPEKIAFMVALGLVTTEHLEEIQSKR
Sbjct: 241 QPESTAESRPPTEEPSQGAQATKKKKEDRPPTQENPEKIAFMVALGLVTTEHLEEIQSKR 300

Query: 259 QERKRRSTANPAYSGLLETERKRLASNYLNNPLFLTARANEDPCWKNEITHDEHCAACKR 318
           QERKRRSTANPAYSGLLETERKRLASNYLNNPLFLTARANEDPCWKNEITHDEHCAACKR
Sbjct: 301 QERKRRSTANPAYSGLLETERKRLASNYLNNPLFLTARANEDPCWKNEITHDEHCAACKR 360

Query: 319 GANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKKDEGVPWTGMLAIVHSYV 378
           GANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKKDEGVPWTGMLAIVHSYV
Sbjct: 361 GANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKKDEGVPWTGMLAIVHSYV 420

Query: 379 THKTVKEEEKQKLLQRGSELQNEHQQLEERDRRLASAVQKCLELKTSLLARQRGTQSSLD 438
           THKTVKEEEKQKLLQRGSELQNEHQQLEERDRRLASAVQKCLELKTSLLARQRGTQSSLD
Sbjct: 421 THKTVKEEEKQKLLQRGSELQNEHQQLEERDRRLASAVQKCLELKTSLLARQRGTQSSLD 480

Query: 439 RLRALLRLIQGEQLLQVTMTTTSPAPLLAGPWTKPSVAATHPTVQHPQGHN 489
           RLRALLRLIQGEQLLQVTMTTTSPAPLLAGPWTKPSVAATHPTVQHPQGHN
Sbjct: 481 RLRALLRLIQGEQLLQVTMTTTSPAPLLAGPWTKPSVAATHPTVQHPQGHN 531


>gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens]
          Length = 634

 Score =  295 bits (754), Expect = 8e-80
 Identities = 171/445 (38%), Positives = 253/445 (56%), Gaps = 39/445 (8%)

Query: 49  PVTGPQVSSLQRLAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPPKQPPTFQKATVVSVKN 108
           P+  PQ     RL  +    LPQVRPK +  +++P+AP        P   Q+  +++   
Sbjct: 213 PIKVPQFIPPPRLTPR-PNFLPQVRPKPVAQNNIPIAPAPPPMLAAPQLIQRPVMLTKFT 271

Query: 109 PSPALPTANNTVSHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSNAAAMAPSTA 168
           P+  LPT+ N++  V     Q   +A+   +A   S       I+  +P    A  P T 
Sbjct: 272 PT-TLPTSQNSIHPVRVVNGQTATIAKTFPMAQLTS-------IVIATPGTRLA-GPQT- 321

Query: 169 VSVVSDSIKVQPLLISADNKVIIIQPQVQTQPESTAESRPPTEEPSQGAQATKKKKEDRP 228
                               V + +P ++ Q   T +S   T+E    ++        +P
Sbjct: 322 --------------------VQLSKPSLEKQ---TVKSHTETDEKQTESRTITPPAAPKP 358

Query: 229 PTQENPEKIAFMVALGLVTTEHLEEIQSKRQERKRRSTANPAYSG-LLETERKRLASNYL 287
             +ENP+K+AFMV+LGLVT +HLEEIQSKRQERKRR+TANP YSG + E ERK+ A  YL
Sbjct: 359 KREENPQKLAFMVSLGLVTHDHLEEIQSKRQERKRRTTANPVYSGAVFEPERKKSAVTYL 418

Query: 288 NNPLF--LTARANEDPCWKNEITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAP 345
           N+ +      RANE+   K +I H++ C+ C++   L  C TC   YHL CL+PPLKT P
Sbjct: 419 NSTMHPGTRKRANEEHWPKGDI-HEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIP 477

Query: 346 KGVWVCPRCQQKALKKDEGVPWTGMLAIVHSYVTHKTVKEEEKQKLLQRGSELQNEHQQL 405
           KG+W+CPRCQ + LKK+E +PW G LAIVHSY+ +K  KEEEKQKLL+  S+L+ E +QL
Sbjct: 478 KGMWICPRCQDQMLKKEEAIPWPGTLAIVHSYIAYKAAKEEEKQKLLKWSSDLKQEREQL 537

Query: 406 EERDRRLASAVQKCLELKTSLLARQRGTQSSLDRLRALLRLIQGEQLLQVTMTTTSPAPL 465
           E++ ++L++++ KC+E+K ++LARQ+   SSL++++ L+RLI G  L +   +  +   +
Sbjct: 538 EQKVKQLSNSISKCMEMKNTILARQKEMHSSLEKVKQLIRLIHGIDLSKPVDSEATVGAI 597

Query: 466 LAGP-WTKPSVAATHPTVQHPQGHN 489
             GP  T P+ AAT      P   +
Sbjct: 598 SNGPDCTPPANAATSTPAPSPSSQS 622



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 54/208 (25%), Positives = 86/208 (41%), Gaps = 41/208 (19%)

Query: 1   MELQSRPEALAVELARHQ-----------NGDLKKQLHERQPRIAALSDKQALGTITAVP 49
           MELQ+  EAL VE+  HQ           N DLKKQLHE Q +I ALS+KQ         
Sbjct: 1   MELQTLQEALKVEIQVHQKLVAQMKQDPQNADLKKQLHELQAKITALSEKQK-------- 52

Query: 50  VTGPQVSSLQRLAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPPKQPPTFQKATVVSVKN- 108
                V  L++       ++ Q +P       LP +  + +  +Q P  Q        + 
Sbjct: 53  ---RVVEQLRK-----NLIVKQEQPDKFQIQPLPQSENKLQTAQQQPLQQLQQQQQYHHH 104

Query: 109 -------PSPALPTANNTVSHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSNAA 161
                   SP L  +  TV+      ++   L   AA A+  +S      ++   P+ A 
Sbjct: 105 HAQQSAAASPNLTASQKTVTTASMITTKTLPLVLKAATATMPAS------VVGQRPTIAM 158

Query: 162 AMAPSTAVSVVSDSIKVQPLLISADNKV 189
             A ++  +V+S  ++  P+ +   +KV
Sbjct: 159 VTAINSQKAVLSTDVQNTPVNLQTSSKV 186


>gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens]
          Length = 680

 Score =  275 bits (702), Expect = 9e-74
 Identities = 170/504 (33%), Positives = 252/504 (50%), Gaps = 88/504 (17%)

Query: 41  ALGTITAVPVTGPQVSSLQRLAGQGAAV-----LPQVRPKTLIPDSLPVAPGRDRPPKQP 95
           A  T+T V  T PQ   + +             LPQVRPK +  +++P+AP        P
Sbjct: 198 AKNTVTLVQATPPQPIKVPQFIPPPRLTPRPNFLPQVRPKPVAQNNIPIAPAPPPMLAAP 257

Query: 96  PTFQKATVVSVKNPSPALPTANNTVSHVPAPGSQPQALAEPAALASPLSSAGVAYAIIST 155
              Q+  +++   P+  LPT+ N++  V     Q   +A+   +A   S       I+  
Sbjct: 258 QLIQRPVMLTKFTPT-TLPTSQNSIHPVRVVNGQTATIAKTFPMAQLTS-------IVIA 309

Query: 156 SPSNAAAMAPSTAVSVVSDSIKVQPLLISADNKVIIIQPQVQTQPESTAESRPPTEEPSQ 215
           +P    A  P T                     V + +P ++ Q   T +S   T+E   
Sbjct: 310 TPGTRLA-GPQT---------------------VQLSKPSLEKQ---TVKSHTETDEKQT 344

Query: 216 GAQATKKKKEDRPPTQENPEKIAFMVALGLVTTEHLEEIQSKRQERKRRSTANPAYSG-L 274
            ++        +P  +ENP+K+AFMV+LGLVT +HLEEIQSKRQERKRR+TANP YSG +
Sbjct: 345 ESRTITPPAAPKPKREENPQKLAFMVSLGLVTHDHLEEIQSKRQERKRRTTANPVYSGAV 404

Query: 275 LETERKRLASNYLNNPLFLTARANEDPCWKNEIT-------------------------- 308
            E ERK+ A  YLN+ +    R    P   N +                           
Sbjct: 405 FEPERKKSAVTYLNSTMHPGTRKRGRPPKYNAVLGFGALTPTSPQSSHPDSPENEKTETT 464

Query: 309 ----------------------HDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPK 346
                                 H++ C+ C++   L  C TC   YHL CL+PPLKT PK
Sbjct: 465 FTFPAPVQPVSLPSPTSTDGDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPK 524

Query: 347 GVWVCPRCQQKALKKDEGVPWTGMLAIVHSYVTHKTVKEEEKQKLLQRGSELQNEHQQLE 406
           G+W+CPRCQ + LKK+E +PW G LAIVHSY+ +K  KEEEKQKLL+  S+L+ E +QLE
Sbjct: 525 GMWICPRCQDQMLKKEEAIPWPGTLAIVHSYIAYKAAKEEEKQKLLKWSSDLKQEREQLE 584

Query: 407 ERDRRLASAVQKCLELKTSLLARQRGTQSSLDRLRALLRLIQGEQLLQVTMTTTSPAPLL 466
           ++ ++L++++ KC+E+K ++LARQ+   SSL++++ L+RLI G  L +   +  +   + 
Sbjct: 585 QKVKQLSNSISKCMEMKNTILARQKEMHSSLEKVKQLIRLIHGIDLSKPVDSEATVGAIS 644

Query: 467 AGP-WTKPSVAATHPTVQHPQGHN 489
            GP  T P+ AAT      P   +
Sbjct: 645 NGPDCTPPANAATSTPAPSPSSQS 668



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 54/208 (25%), Positives = 86/208 (41%), Gaps = 41/208 (19%)

Query: 1   MELQSRPEALAVELARHQ-----------NGDLKKQLHERQPRIAALSDKQALGTITAVP 49
           MELQ+  EAL VE+  HQ           N DLKKQLHE Q +I ALS+KQ         
Sbjct: 1   MELQTLQEALKVEIQVHQKLVAQMKQDPQNADLKKQLHELQAKITALSEKQK-------- 52

Query: 50  VTGPQVSSLQRLAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPPKQPPTFQKATVVSVKN- 108
                V  L++       ++ Q +P       LP +  + +  +Q P  Q        + 
Sbjct: 53  ---RVVEQLRK-----NLIVKQEQPDKFQIQPLPQSENKLQTAQQQPLQQLQQQQQYHHH 104

Query: 109 -------PSPALPTANNTVSHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSNAA 161
                   SP L  +  TV+      ++   L   AA A+  +S      ++   P+ A 
Sbjct: 105 HAQQSAAASPNLTASQKTVTTASMITTKTLPLVLKAATATMPAS------VVGQRPTIAM 158

Query: 162 AMAPSTAVSVVSDSIKVQPLLISADNKV 189
             A ++  +V+S  ++  P+ +   +KV
Sbjct: 159 VTAINSQKAVLSTDVQNTPVNLQTSSKV 186


>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
           sapiens]
          Length = 1954

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 30/62 (48%), Positives = 33/62 (53%)

Query: 299 EDPCWKNEITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKA 358
           E  C + E  H E C  CK G  L  C  CP +YHL CL PPL   P G W+CPRC    
Sbjct: 405 EGGCEEEEDDHMEFCRVCKDGGELLCCDACPSSYHLHCLNPPLPEIPNGEWLCPRCTCPP 464

Query: 359 LK 360
           LK
Sbjct: 465 LK 466



 Score = 69.7 bits (169), Expect = 6e-12
 Identities = 27/62 (43%), Positives = 38/62 (61%), Gaps = 6/62 (9%)

Query: 306 EITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKKDEGV 365
           E  H ++C  C++G  +  C TCP AYHL CL+P L+ AP+G W CP C++      EG+
Sbjct: 339 ETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELEKAPEGKWSCPHCEK------EGI 392

Query: 366 PW 367
            W
Sbjct: 393 QW 394


>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
           [Homo sapiens]
          Length = 2000

 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 31/73 (42%), Positives = 41/73 (56%), Gaps = 6/73 (8%)

Query: 295 ARANEDPCWKNEITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRC 354
           A A E+     E  H ++C  C++G  +  C TCP AYHL CL+P L  AP+G W CP C
Sbjct: 364 AVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHC 423

Query: 355 QQKALKKDEGVPW 367
           ++      EGV W
Sbjct: 424 EK------EGVQW 430



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 26/57 (45%), Positives = 31/57 (54%)

Query: 304 KNEITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALK 360
           + E  H E+C  CK G  L  C  C  +YH+ CL PPL   P G W+CPRC    LK
Sbjct: 450 EEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRCTCPVLK 506


>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
           [Homo sapiens]
          Length = 1966

 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 31/73 (42%), Positives = 41/73 (56%), Gaps = 6/73 (8%)

Query: 295 ARANEDPCWKNEITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRC 354
           A A E+     E  H ++C  C++G  +  C TCP AYHL CL+P L  AP+G W CP C
Sbjct: 364 AVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHC 423

Query: 355 QQKALKKDEGVPW 367
           ++      EGV W
Sbjct: 424 EK------EGVQW 430



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 26/57 (45%), Positives = 31/57 (54%)

Query: 304 KNEITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALK 360
           + E  H E+C  CK G  L  C  C  +YH+ CL PPL   P G W+CPRC    LK
Sbjct: 450 EEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRCTCPVLK 506


>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
           [Homo sapiens]
          Length = 2059

 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 31/73 (42%), Positives = 41/73 (56%), Gaps = 6/73 (8%)

Query: 295 ARANEDPCWKNEITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRC 354
           A A E+     E  H ++C  C++G  +  C TCP AYHL CL+P L  AP+G W CP C
Sbjct: 423 AVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHC 482

Query: 355 QQKALKKDEGVPW 367
           ++      EGV W
Sbjct: 483 EK------EGVQW 489



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 26/57 (45%), Positives = 31/57 (54%)

Query: 304 KNEITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALK 360
           + E  H E+C  CK G  L  C  C  +YH+ CL PPL   P G W+CPRC    LK
Sbjct: 509 EEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRCTCPVLK 565


>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
           sapiens]
          Length = 1912

 Score = 69.7 bits (169), Expect = 6e-12
 Identities = 28/52 (53%), Positives = 31/52 (59%)

Query: 309 HDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALK 360
           H E C  CK G  L  C TCP +YH+ CL PPL   P G W+CPRC   ALK
Sbjct: 448 HMEFCRVCKDGGELLCCDTCPSSYHIHCLNPPLPEIPNGEWLCPRCTCPALK 499



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 25/62 (40%), Positives = 38/62 (61%), Gaps = 6/62 (9%)

Query: 306 EITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKKDEGV 365
           E  H ++C  C++G  +  C TCP AYH+ CL+P ++ AP+G W CP C++      EG+
Sbjct: 366 ETDHQDYCEVCQQGGEIILCDTCPRAYHMVCLDPDMEKAPEGKWSCPHCEK------EGI 419

Query: 366 PW 367
            W
Sbjct: 420 QW 421



 Score = 35.8 bits (81), Expect = 0.091
 Identities = 47/188 (25%), Positives = 70/188 (37%), Gaps = 33/188 (17%)

Query: 105  SVKNPSPALPTANNTVSHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSNAAAMA 164
            S K P+P+ P      +  P P ++     E  +L    S  G              + A
Sbjct: 1537 SPKTPTPSTPGDTQPNTPAPVPPAEDGIKIEENSLKEEESIEG---------EKEVKSTA 1587

Query: 165  PSTAVSVVSDSIKVQPLLISADNKVIIIQPQVQTQPESTAESRPPTEEPSQ----GAQAT 220
            P TA+          P   S D KV++  P+ + + E  AE +  TEEP +    GA   
Sbjct: 1588 PETAIECTQ-----APAPASEDEKVVVEPPEGEEKVEK-AEVKERTEEPMETEPKGAADV 1641

Query: 221  KKKK------------EDRPPTQENPEKIAFMVALGLVTTEHLEEIQSKRQERKRRSTAN 268
            +K +            ED+   +E  EK   M+  G    +  +E Q K    K+R   N
Sbjct: 1642 EKVEEKSAIDLTPIVVEDKEEKKEEEEKKEVMLQNGETPKDLNDEKQKK--NIKQRFMFN 1699

Query: 269  PAYSGLLE 276
             A  G  E
Sbjct: 1700 IADGGFTE 1707


>gi|4557293 autoimmune regulator isoform 2 [Homo sapiens]
          Length = 348

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 26/60 (43%), Positives = 34/60 (56%), Gaps = 4/60 (6%)

Query: 302 CWKNEITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKK 361
           C KNE    + CA C+ G  L  C  CP A+HL+CL PPL+  P G W C  C Q  +++
Sbjct: 95  CQKNE----DECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQE 150


>gi|75677357 PHD finger protein 12 isoform 1 [Homo sapiens]
          Length = 1004

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 2/93 (2%)

Query: 273 GLLETERKRLASNYLNNPLFLTARANEDPCWKNEITHDEHCAACKRGANLQPCGTCPGAY 332
           GL+E  +  LA    +     + +  ++P      T+ + C +CK G +L  C  CP A+
Sbjct: 19  GLMEQIQALLAPPKTDEAEKRSRKPEKEPRRSGRATNHDSCDSCKEGGDLLCCDHCPAAF 78

Query: 333 HLSCLEPPL--KTAPKGVWVCPRCQQKALKKDE 363
           HL C  PPL  +  P G W+C RC  +  K+++
Sbjct: 79  HLQCCNPPLSEEMLPPGEWMCHRCTVRRKKREQ 111



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 27/122 (22%), Positives = 53/122 (43%), Gaps = 6/122 (4%)

Query: 313 CAACKRGANLQP---CGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKKDEGVPWTG 369
           C  C R   + P   C  CP  +H+ CLEPPL   P G W+CP   +  +   + +  + 
Sbjct: 274 CFTCNRSCRVAPLIQCDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVVLNQKNMTLSN 333

Query: 370 MLAIVHSY---VTHKTVKEEEKQKLLQRGSELQNEHQQLEERDRRLASAVQKCLELKTSL 426
              +   +   V+   VK +   ++ ++    +   Q ++ R  ++  A++   +    L
Sbjct: 334 RCQVFDRFQDTVSQHVVKVDFLNRIHKKHPPNRRVLQSVKRRSLKVPDAIKSQYQFPPPL 393

Query: 427 LA 428
           +A
Sbjct: 394 IA 395


>gi|30842829 PHD finger protein 12 isoform 2 [Homo sapiens]
          Length = 704

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 2/93 (2%)

Query: 273 GLLETERKRLASNYLNNPLFLTARANEDPCWKNEITHDEHCAACKRGANLQPCGTCPGAY 332
           GL+E  +  LA    +     + +  ++P      T+ + C +CK G +L  C  CP A+
Sbjct: 19  GLMEQIQALLAPPKTDEAEKRSRKPEKEPRRSGRATNHDSCDSCKEGGDLLCCDHCPAAF 78

Query: 333 HLSCLEPPL--KTAPKGVWVCPRCQQKALKKDE 363
           HL C  PPL  +  P G W+C RC  +  K+++
Sbjct: 79  HLQCCNPPLSEEMLPPGEWMCHRCTVRRKKREQ 111



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 27/122 (22%), Positives = 53/122 (43%), Gaps = 6/122 (4%)

Query: 313 CAACKRGANLQP---CGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKKDEGVPWTG 369
           C  C R   + P   C  CP  +H+ CLEPPL   P G W+CP   +  +   + +  + 
Sbjct: 274 CFTCNRSCRVAPLIQCDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVVLNQKNMTLSN 333

Query: 370 MLAIVHSY---VTHKTVKEEEKQKLLQRGSELQNEHQQLEERDRRLASAVQKCLELKTSL 426
              +   +   V+   VK +   ++ ++    +   Q ++ R  ++  A++   +    L
Sbjct: 334 RCQVFDRFQDTVSQHVVKVDFLNRIHKKHPPNRRVLQSVKRRSLKVPDAIKSQYQFPPPL 393

Query: 427 LA 428
           +A
Sbjct: 394 IA 395


>gi|4557291 autoimmune regulator isoform 1 [Homo sapiens]
          Length = 545

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 22/53 (41%), Positives = 32/53 (60%)

Query: 309 HDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKK 361
           +++ CA C+ G  L  C  CP A+HL+CL PPL+  P G W C  C Q  +++
Sbjct: 295 NEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQE 347


>gi|38788260 bromodomain PHD finger transcription factor isoform 2
           [Homo sapiens]
          Length = 2903

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 26/77 (33%), Positives = 38/77 (49%)

Query: 278 ERKRLASNYLNNPLFLTARANEDPCWKNEITHDEHCAACKRGANLQPCGTCPGAYHLSCL 337
           E K     +L +    T  A E+   +  I +D+HC  C +  +L  C TC   YHL C+
Sbjct: 358 ENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECV 417

Query: 338 EPPLKTAPKGVWVCPRC 354
           +PPL+  P+  W C  C
Sbjct: 418 KPPLEEVPEDEWQCEVC 434



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 63/242 (26%), Positives = 91/242 (37%), Gaps = 40/242 (16%)

Query: 48   VPVTGPQVSSLQRLAG--QGAAVLPQVRPKT-----LIPDSLPVAPGRDRPPKQPP---- 96
            V +T  Q++ L +  G  QG  V+ Q + +T     LIP  + V PG  +   Q      
Sbjct: 2271 VKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNG 2330

Query: 97   TFQKATVVSVKNPSPALPTANNTVSHVPA-PGSQPQALAEPAALASPLSSAGVAYAIIST 155
            T Q+     +   +    T   TVS   A  G Q Q+   P        +   A +  S 
Sbjct: 2331 TVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSS-SV 2389

Query: 156  SPSNAAAMAPSTAVSVVSDSIKVQPLLISADNKVIIIQPQVQTQPE----STAESRPPTE 211
             P+ A    P TA        + QP   +        QP+VQTQPE    +T  S  P+E
Sbjct: 2390 GPAEAQ---PQTAQPSAQPQPQTQPQSPA--------QPEVQTQPEVQTQTTVSSHVPSE 2438

Query: 212  EPSQGAQATKKKKEDRPPTQENPEKIAFMVALGLVTTEHLEEIQSKRQERKRRSTANPAY 271
                 AQ++K +   +   Q N            V  +    +QS  Q R R ST +   
Sbjct: 2439 AQPTHAQSSKPQVAAQSQPQSN------------VQGQSPVRVQSPSQTRIRPSTPSQLS 2486

Query: 272  SG 273
             G
Sbjct: 2487 PG 2488


>gi|38788274 bromodomain PHD finger transcription factor isoform 1
           [Homo sapiens]
          Length = 2920

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 26/77 (33%), Positives = 38/77 (49%)

Query: 278 ERKRLASNYLNNPLFLTARANEDPCWKNEITHDEHCAACKRGANLQPCGTCPGAYHLSCL 337
           E K     +L +    T  A E+   +  I +D+HC  C +  +L  C TC   YHL C+
Sbjct: 358 ENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECV 417

Query: 338 EPPLKTAPKGVWVCPRC 354
           +PPL+  P+  W C  C
Sbjct: 418 KPPLEEVPEDEWQCEVC 434



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 63/242 (26%), Positives = 91/242 (37%), Gaps = 40/242 (16%)

Query: 48   VPVTGPQVSSLQRLAG--QGAAVLPQVRPKT-----LIPDSLPVAPGRDRPPKQPP---- 96
            V +T  Q++ L +  G  QG  V+ Q + +T     LIP  + V PG  +   Q      
Sbjct: 2145 VKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNG 2204

Query: 97   TFQKATVVSVKNPSPALPTANNTVSHVPA-PGSQPQALAEPAALASPLSSAGVAYAIIST 155
            T Q+     +   +    T   TVS   A  G Q Q+   P        +   A +  S 
Sbjct: 2205 TVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSS-SV 2263

Query: 156  SPSNAAAMAPSTAVSVVSDSIKVQPLLISADNKVIIIQPQVQTQPE----STAESRPPTE 211
             P+ A    P TA        + QP   +        QP+VQTQPE    +T  S  P+E
Sbjct: 2264 GPAEAQ---PQTAQPSAQPQPQTQPQSPA--------QPEVQTQPEVQTQTTVSSHVPSE 2312

Query: 212  EPSQGAQATKKKKEDRPPTQENPEKIAFMVALGLVTTEHLEEIQSKRQERKRRSTANPAY 271
                 AQ++K +   +   Q N            V  +    +QS  Q R R ST +   
Sbjct: 2313 AQPTHAQSSKPQVAAQSQPQSN------------VQGQSPVRVQSPSQTRIRPSTPSQLS 2360

Query: 272  SG 273
             G
Sbjct: 2361 PG 2362



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 38/177 (21%), Positives = 66/177 (37%), Gaps = 16/177 (9%)

Query: 30   QPRIAALSDKQALGTITAVPVTGPQVSSLQRLAGQGAAVLPQVRPKTLIPDSLPV---AP 86
            QP +    + Q   T+++   +  Q +  Q    Q AA   Q +P++ +    PV   +P
Sbjct: 2290 QPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAA---QSQPQSNVQGQSPVRVQSP 2346

Query: 87   GRDR-----PPKQPPTFQKATVVSVKNPSPALPTANNTVSHVPAPGSQPQALAEPAALAS 141
             + R     P +  P  Q     +   P P  P  +  +     P SQPQ  +       
Sbjct: 2347 SQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSS----TQ 2402

Query: 142  PLSSAGVAYAIISTSPSNAAAMAPSTAVSVVS-DSIKVQPLLISADNKVIIIQPQVQ 197
             LSS      +  +SPS            V++   ++ Q  ++S     ++ Q Q Q
Sbjct: 2403 TLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQ 2459


>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
           [Homo sapiens]
          Length = 1050

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 66/254 (25%), Positives = 97/254 (38%), Gaps = 46/254 (18%)

Query: 114 PTANNTV----SHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSNAAAMAPSTAV 169
           P +N TV    S VP+PG           LA P++   V   I S S S+  +   S + 
Sbjct: 652 PPSNRTVQSPNSSVPSPG-----------LAGPVTMTSVHPPIRSPSASSVGSRGSSGSS 700

Query: 170 SVVSDSIKVQPLLISADNKVIIIQPQVQTQP-ESTAESRPPTEEPSQGAQATKKK--KED 226
           S        +P    + +KV    P V  +P     E+  P E         K++  +E 
Sbjct: 701 S--------KPAGADSTHKV----PVVMLEPIRIKQENSGPPENYDFPVVIVKQESDEES 748

Query: 227 RPPTQENPEKIAFMVALGLVTTEHLEEIQSKRQERKRRSTANPAYSGLLETERKRLASNY 286
           RP     P  I   + L    +   EE       R     +     GL +       S +
Sbjct: 749 RPQNANYPRSILTSLLLNSSQSSTSEETVL----RSDAPDSTGDQPGLHQDNSSNGKSEW 804

Query: 287 LN----NPLFL-TARANEDPCWKNEITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPL 341
           L+    +PL +   R  +DP       +++ CA C+ G  L  C  CP  +HLSC  P L
Sbjct: 805 LDPSQKSPLHVGETRKEDDP-------NEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTL 857

Query: 342 KTAPKGVWVCPRCQ 355
              P G W+C  C+
Sbjct: 858 TNFPSGEWICTFCR 871


>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
           [Homo sapiens]
          Length = 1016

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 66/254 (25%), Positives = 97/254 (38%), Gaps = 46/254 (18%)

Query: 114 PTANNTV----SHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSNAAAMAPSTAV 169
           P +N TV    S VP+PG           LA P++   V   I S S S+  +   S + 
Sbjct: 618 PPSNRTVQSPNSSVPSPG-----------LAGPVTMTSVHPPIRSPSASSVGSRGSSGSS 666

Query: 170 SVVSDSIKVQPLLISADNKVIIIQPQVQTQP-ESTAESRPPTEEPSQGAQATKKK--KED 226
           S        +P    + +KV    P V  +P     E+  P E         K++  +E 
Sbjct: 667 S--------KPAGADSTHKV----PVVMLEPIRIKQENSGPPENYDFPVVIVKQESDEES 714

Query: 227 RPPTQENPEKIAFMVALGLVTTEHLEEIQSKRQERKRRSTANPAYSGLLETERKRLASNY 286
           RP     P  I   + L    +   EE       R     +     GL +       S +
Sbjct: 715 RPQNANYPRSILTSLLLNSSQSSTSEETVL----RSDAPDSTGDQPGLHQDNSSNGKSEW 770

Query: 287 LN----NPLFL-TARANEDPCWKNEITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPL 341
           L+    +PL +   R  +DP       +++ CA C+ G  L  C  CP  +HLSC  P L
Sbjct: 771 LDPSQKSPLHVGETRKEDDP-------NEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTL 823

Query: 342 KTAPKGVWVCPRCQ 355
              P G W+C  C+
Sbjct: 824 TNFPSGEWICTFCR 837


>gi|74027251 tripartite motif-containing 33 protein isoform beta
           [Homo sapiens]
          Length = 1110

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 72/326 (22%), Positives = 130/326 (39%), Gaps = 46/326 (14%)

Query: 44  TITAVPVTGPQVSSLQRLAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPPKQPPTFQKATV 103
           TI     T   +++  R     +    ++ P    P++LP  P  D PP Q    + A  
Sbjct: 639 TINPTSPTTATMANANRGPTSPSVTAIELIPSVTNPENLPSLP--DIPPIQ---LEDAGS 693

Query: 104 VSVKNPSPALPTANNTVSHVPAPGSQPQALAEPAALASPLS--SAGVAYAIISTSPSNAA 161
            S+ N    L +   + SH+P    QP +   P+   S LS  S+G++ +     P + +
Sbjct: 694 SSLDN----LLSRYISGSHLPP---QPTSTMNPSPGPSALSPGSSGLSNSHTPVRPPSTS 746

Query: 162 AM------------APSTAVSVVSDSIKVQPLLISADNKVIIIQPQVQTQPESTAESRPP 209
           +             A  T++S  SD +KV+    + D    I       + E T + R  
Sbjct: 747 STGSRGSCGSSGRTAEKTSLSFKSDQVKVKQEPGTEDE---ICSFSGGVKQEKTEDGR-- 801

Query: 210 TEEPSQGAQATKKKKEDRPPTQENPEKIAFMVALGLVTTEHLEEIQSKRQERKRRSTANP 269
                     +  +    PP   N    + + AL  +   H++   +   E  ++S  + 
Sbjct: 802 ----RSACMLSSPESSLTPPLSTNLHLESELDALASLEN-HVKIEPADMNESCKQSGLSS 856

Query: 270 AYSGLLETERKRLASNYLNNPLFLTARANEDPCWKNEITHDEHCAACKRGANLQPCGTCP 329
             +G           + + + +  +AR   D   K++  +++ CA C+ G +L  C  CP
Sbjct: 857 LVNG----------KSPIRSLMHRSARIGGDGNNKDDDPNEDWCAVCQNGGDLLCCEKCP 906

Query: 330 GAYHLSCLEPPLKTAPKGVWVCPRCQ 355
             +HL+C  P L + P G W+C  C+
Sbjct: 907 KVFHLTCHVPTLLSFPSGDWICTFCR 932


>gi|74027249 tripartite motif-containing 33 protein isoform alpha
           [Homo sapiens]
          Length = 1127

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 72/326 (22%), Positives = 130/326 (39%), Gaps = 46/326 (14%)

Query: 44  TITAVPVTGPQVSSLQRLAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPPKQPPTFQKATV 103
           TI     T   +++  R     +    ++ P    P++LP  P  D PP Q    + A  
Sbjct: 639 TINPTSPTTATMANANRGPTSPSVTAIELIPSVTNPENLPSLP--DIPPIQ---LEDAGS 693

Query: 104 VSVKNPSPALPTANNTVSHVPAPGSQPQALAEPAALASPLS--SAGVAYAIISTSPSNAA 161
            S+ N    L +   + SH+P    QP +   P+   S LS  S+G++ +     P + +
Sbjct: 694 SSLDN----LLSRYISGSHLPP---QPTSTMNPSPGPSALSPGSSGLSNSHTPVRPPSTS 746

Query: 162 AM------------APSTAVSVVSDSIKVQPLLISADNKVIIIQPQVQTQPESTAESRPP 209
           +             A  T++S  SD +KV+    + D    I       + E T + R  
Sbjct: 747 STGSRGSCGSSGRTAEKTSLSFKSDQVKVKQEPGTEDE---ICSFSGGVKQEKTEDGR-- 801

Query: 210 TEEPSQGAQATKKKKEDRPPTQENPEKIAFMVALGLVTTEHLEEIQSKRQERKRRSTANP 269
                     +  +    PP   N    + + AL  +   H++   +   E  ++S  + 
Sbjct: 802 ----RSACMLSSPESSLTPPLSTNLHLESELDALASLEN-HVKIEPADMNESCKQSGLSS 856

Query: 270 AYSGLLETERKRLASNYLNNPLFLTARANEDPCWKNEITHDEHCAACKRGANLQPCGTCP 329
             +G           + + + +  +AR   D   K++  +++ CA C+ G +L  C  CP
Sbjct: 857 LVNG----------KSPIRSLMHRSARIGGDGNNKDDDPNEDWCAVCQNGGDLLCCEKCP 906

Query: 330 GAYHLSCLEPPLKTAPKGVWVCPRCQ 355
             +HL+C  P L + P G W+C  C+
Sbjct: 907 KVFHLTCHVPTLLSFPSGDWICTFCR 932


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 49/175 (28%), Positives = 73/175 (41%), Gaps = 16/175 (9%)

Query: 53   PQVSSLQRLAGQGAAVLPQVRPKTLIPDSLPVAP-GRDRPPKQPPTFQKATVVSVKNPSP 111
            P ++   R    G   +   RP TL P  LP    G  R P   PT  +  +  V +PSP
Sbjct: 1325 PPLAPAPRPPSSGLPAVLNPRP-TLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSP 1383

Query: 112  --------ALPTANNTVSHVPA----PGSQPQALAEPAALASPLSSAGVAYAIISTSPSN 159
                    A P   ++  HVP+    P S P  +   + LASP+SS  V+  + S+ P +
Sbjct: 1384 EVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSST-VSVPLSSSLPIS 1442

Query: 160  AAAMAPSTAVSVVSDSIKVQPLLISADNKVIIIQPQVQTQPESTAESRPPTEEPS 214
                 P+ A + ++  I   PL +SA    ++        P   A   PP+  PS
Sbjct: 1443 VPTTLPAPASAPLTIPISA-PLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPS 1496



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 48/238 (20%), Positives = 90/238 (37%), Gaps = 18/238 (7%)

Query: 45   ITAVPVTGPQVSSLQRLAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPPKQPPTFQKATVV 104
            + A  +  P+   L  +A    + L  V PK L+P ++ + P  ++     P+    T+ 
Sbjct: 2553 LCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLE 2612

Query: 105  SVKNPSPALPTA-----NNTVSHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSN 159
            +   P+     A       T++ +P     P  ++E   L  P S+A       S  P  
Sbjct: 2613 AGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAA-------SDEPLQ 2665

Query: 160  AAAMAPSTAVSVV-----SDSIKVQPLLISADNKVIIIQPQVQTQPESTAESRPPTEEPS 214
                A  T+  +      + S +    L++A+           + PE  + +RPP    S
Sbjct: 2666 EPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTS 2725

Query: 215  QGAQATKKKKEDRPPTQENPEKIAFMVALGLVTTEHLEEIQSKRQERKRRSTANPAYS 272
               +  + +   RP     P+ +  +    +   E  E ++ +RQ+R   ST  P  S
Sbjct: 2726 ADVE-IRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVS 2782



 Score = 37.0 bits (84), Expect = 0.041
 Identities = 45/181 (24%), Positives = 70/181 (38%), Gaps = 16/181 (8%)

Query: 31   PRIAALSDKQALGTITAVPVTGPQVSSLQRLAGQGAAVLPQVRPKTLIPDSLPVAPGRDR 90
            P +A  S +  L      P+  P  +    LA   A  L    P      +L +  G  +
Sbjct: 1653 PVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPS----QTLSLGTGNPQ 1708

Query: 91   PPKQPPTFQKATVVSVKNPSPALPTANNTVSHVPAPGSQPQ-----ALAEPAALASPLSS 145
             P    T      +S+   S  +PT   T+S  P P   P      A A P A ASP+  
Sbjct: 1709 GPFPTQT------LSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGP 1762

Query: 146  AGVAYAIISTSPSNAAAMAPSTAVSVVSDSIKVQPLLISADNKVIIIQPQVQTQPESTAE 205
            A      ++ + S+A+ +AP++  ++      V P L  A  + + + P     P S A 
Sbjct: 1763 APAHTLTLAPASSSASLLAPASVQTLTLSPAPV-PTLGPAAAQTLALAPASTQSPASQAS 1821

Query: 206  S 206
            S
Sbjct: 1822 S 1822



 Score = 32.7 bits (73), Expect = 0.77
 Identities = 29/85 (34%), Positives = 32/85 (37%), Gaps = 21/85 (24%)

Query: 82   LPVAPGRDRPPKQPPTFQKA-------------TVVSVKNPS------PALPTANNTVSH 122
            L VA   D PP+  P   K              TVV V NP       P  P     +S 
Sbjct: 975  LEVATAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSA 1034

Query: 123  VPAPGSQPQALAEPAALASPLSSAG 147
             P PG  PQ L  PA+L    S AG
Sbjct: 1035 QPTPGPVPQVL--PASLMVSASPAG 1057



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 39/159 (24%), Positives = 63/159 (39%), Gaps = 12/159 (7%)

Query: 22   LKKQLHERQPRIAALSDKQALGTITA---VPVTGPQVSSLQRLAGQGAAVLPQVRPKTLI 78
            L K +H   P ++A +   A  TI++   VP + P  +S        + +   V     +
Sbjct: 1374 LLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSV 1433

Query: 79   P--DSLPVAPGRD--RPPKQPPTFQKATVVSVKNPSPAL-----PTANNTVSHVPAPGSQ 129
            P   SLP++       P   P T   +  ++V    PAL     P     V   P P S 
Sbjct: 1434 PLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSL 1493

Query: 130  PQALAEPAALASPLSSAGVAYAIISTSPSNAAAMAPSTA 168
              + A P+A A  L  A       S +P +   +AP+++
Sbjct: 1494 APSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSS 1532


>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
          Length = 1441

 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 37/123 (30%), Positives = 53/123 (43%), Gaps = 25/123 (20%)

Query: 310  DEHCAACKRGANLQP-----CGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKAL--KKD 362
            DE C  C  G    P     C +C   YH +CL PPL   P G W CP CQ K L  K +
Sbjct: 891  DEPCKKC--GLPNHPELILLCDSCDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCEKLE 948

Query: 363  EGVPWTGMLAIVHSYVTHKTVKEEEKQKLLQRGSELQN----------EHQQLEERDRRL 412
            E       L  +   +  K   E  K++L+  G  ++N          E Q+ +++D + 
Sbjct: 949  E------QLQDLDVALKKKERAERRKERLVYVGISIENIIPPQEPDFSEDQEEKKKDSKK 1002

Query: 413  ASA 415
            + A
Sbjct: 1003 SKA 1005


>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
          Length = 1216

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 21/49 (42%), Positives = 27/49 (55%)

Query: 307  ITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQ 355
            I +++ CA C  G  L  C  CP  +HLSC  P L + P G WVC  C+
Sbjct: 967  IENEDFCAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPGGEWVCTLCR 1015



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 32/164 (19%), Positives = 64/164 (39%), Gaps = 14/164 (8%)

Query: 93  KQPPTFQKATVVSVKNPSPALPTANNTVSHVPAPGSQPQALAEPAALASPLSSAGVAYAI 152
           +QP   Q  +       +   P +  +   +P   +   AL + +   +PLS   V   I
Sbjct: 556 RQPAPVQSQSQEETLQATDEPPASQGSKPALPLDKNTAAALPQASGEETPLSVPPVDSTI 615

Query: 153 ISTSPSNAAAMAPSTAVSVVSDSIKVQPLLISADNKVIIIQPQVQTQPESTAESRPPTEE 212
             +SP+     + S ++   S++++++   +S+      ++PQ+Q+    TA        
Sbjct: 616 QHSSPNVVRKHSTSLSIMGFSNTLEME---LSSTRLERPLEPQIQSVSNLTA-------- 664

Query: 213 PSQGAQATKKKKEDRPPTQENPEKIAFMVALGLVTTEHLEEIQS 256
              GA          PP   +        A+  +TT HL+ + S
Sbjct: 665 ---GAPQAVPSLLSAPPKMVSSLTSVQNQAMPSLTTSHLQTVPS 705


>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
          Length = 948

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 49/174 (28%), Positives = 64/174 (36%), Gaps = 42/174 (24%)

Query: 196 VQTQPESTAESRPPTEEPSQGAQATKKKKEDRPPTQENPEKIAFMVALGLVTTEHLEEIQ 255
           ++T P+ T  SR   +EP       K   +D PP    P+KI                 +
Sbjct: 790 METLPDGTKRSRRQIKEP------VKFVPQDVPP---EPKKIPIRNTRTRGRKRSFVPEE 840

Query: 256 SKRQERKRRSTANPAYSGLLETERKRLASNYLNNPLFLTARANEDPCWKNEITHDEHCAA 315
            K +ER  R             ER++  S     P             K E    E CA 
Sbjct: 841 EKHEERVPR-------------ERRQRQSVLQKKP-------------KAEDLRTE-CAT 873

Query: 316 CKR---GANLQPCGTCPGAYHLSCLEPPLKTAPKGV---WVCPRCQQKALKKDE 363
           CK      NL  C  C   YH  CL+PPLK +PK     W+C  C   + K+DE
Sbjct: 874 CKGTGDNENLVRCDECRLCYHFGCLDPPLKKSPKQTGYGWICQECDSSSSKEDE 927



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 36/123 (29%), Positives = 45/123 (36%), Gaps = 22/123 (17%)

Query: 249 EHLEEIQSKRQERKRRSTANPAYSGLLETERKRLASNYLNNPLFLTARANEDPCWKNEIT 308
           E LEE+Q+   + +       A  G       R+    LN P  L A     P  K   T
Sbjct: 663 ESLEELQNLNGKLRSEGQGIWALLG-------RITGQKLNIPAILRAPKERKPSKKEGGT 715

Query: 309 HDEH--------CAACKRGAN---LQPCGTCPGAYHLSCLEPPLKTAPK----GVWVCPR 353
                       C  CK+  +   L  C TC   YHL CL+PPL   P+      W C  
Sbjct: 716 QKTSTLPAVLYSCGICKKNHDQHLLLLCDTCKLHYHLGCLDPPLTRMPRKTKNSYWQCSE 775

Query: 354 CQQ 356
           C Q
Sbjct: 776 CDQ 778


>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform b
            [Homo sapiens]
          Length = 1524

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 5/97 (5%)

Query: 265  STANPAYSGLLETERKRLASNYLNNPLFL-TARANEDPCWKNEITHDEHCAACKR---GA 320
            S +  +Y  +L+  R+ L S+   + +FL  +  +    W   I +   C  C++     
Sbjct: 1071 SDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVIWSKSILN-ARCKICRKKGDAE 1129

Query: 321  NLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQK 357
            N+  C  C   +H  C+ P LKT P+G W CP C+ K
Sbjct: 1130 NMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPK 1166


>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform a
            [Homo sapiens]
          Length = 1556

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 5/97 (5%)

Query: 265  STANPAYSGLLETERKRLASNYLNNPLFL-TARANEDPCWKNEITHDEHCAACKR---GA 320
            S +  +Y  +L+  R+ L S+   + +FL  +  +    W   I +   C  C++     
Sbjct: 1103 SDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVIWSKSILN-ARCKICRKKGDAE 1161

Query: 321  NLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQK 357
            N+  C  C   +H  C+ P LKT P+G W CP C+ K
Sbjct: 1162 NMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPK 1198


>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 64/222 (28%), Positives = 93/222 (41%), Gaps = 50/222 (22%)

Query: 27   HERQPRIAALSDKQALGTITAVPVT-------GPQVSSLQRLAGQGAAVLPQVRPKTLIP 79
            H   P I A   +Q   T    PV        GPQ  +L     Q         P+ + P
Sbjct: 843  HHTPPSIGA---QQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQP 899

Query: 80   DSLPVAPGRDRPPKQPPTFQKATVVSVKNP-SPALPTANNTVSHVPAPGSQPQALAEPAA 138
             SLP AP  D+P +QP + Q++T  SV  P +P LP         P P            
Sbjct: 900  -SLPAAPSADQPQQQPRS-QQSTAASVPTPTAPLLP---------PQP------------ 936

Query: 139  LASPLSSAGVAY-AIISTSPSNAAAMAPSTAVSVVSDSIKVQPLLISADNKVIIIQPQ-V 196
             A+PLS   V+    +S  PS ++    S A++    S +V+      + K+ + QP+  
Sbjct: 937  -ATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVK-----MEAKMEVDQPEPA 990

Query: 197  QTQPESTAESR--------PPTEEPSQGAQATKKKKEDRPPT 230
             TQPE  +ES+          TEE S   +   K++ED+P T
Sbjct: 991  DTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPST 1032


>gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [Homo
           sapiens]
          Length = 1379

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 23/52 (44%), Positives = 26/52 (50%), Gaps = 3/52 (5%)

Query: 313 CAACKRGAN---LQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKK 361
           C  C RG     L  C  C   YH+ CL PPL   PKGVW CP+C     K+
Sbjct: 260 CRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKR 311


>gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [Homo
           sapiens]
          Length = 1560

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 23/52 (44%), Positives = 26/52 (50%), Gaps = 3/52 (5%)

Query: 313 CAACKRGAN---LQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKK 361
           C  C RG     L  C  C   YH+ CL PPL   PKGVW CP+C     K+
Sbjct: 327 CRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKR 378


>gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo
           sapiens]
          Length = 1690

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 23/52 (44%), Positives = 26/52 (50%), Gaps = 3/52 (5%)

Query: 313 CAACKRGAN---LQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKK 361
           C  C RG N   L  C  C  +YH  CL PPL   PKG W CP+C  +   K
Sbjct: 296 CMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSK 347


>gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo
           sapiens]
          Length = 1641

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 23/52 (44%), Positives = 26/52 (50%), Gaps = 3/52 (5%)

Query: 313 CAACKRGAN---LQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKK 361
           C  C RG N   L  C  C  +YH  CL PPL   PKG W CP+C  +   K
Sbjct: 296 CMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSK 347


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.126    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,272,328
Number of Sequences: 37866
Number of extensions: 1123305
Number of successful extensions: 7968
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 128
Number of HSP's successfully gapped in prelim test: 537
Number of HSP's that attempted gapping in prelim test: 6614
Number of HSP's gapped (non-prelim): 1686
length of query: 489
length of database: 18,247,518
effective HSP length: 106
effective length of query: 383
effective length of database: 14,233,722
effective search space: 5451515526
effective search space used: 5451515526
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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