BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|208610002 atlastin GTPase 2 isoform 2 [Homo sapiens] (583 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|208610002 atlastin GTPase 2 isoform 2 [Homo sapiens] 1181 0.0 gi|208610000 atlastin GTPase 2 isoform 1 [Homo sapiens] 1109 0.0 gi|189181742 atlastin GTPase 1 isoform b [Homo sapiens] 761 0.0 gi|74024917 atlastin GTPase 1 isoform b [Homo sapiens] 761 0.0 gi|19923445 atlastin GTPase 1 isoform a [Homo sapiens] 759 0.0 gi|45827806 atlastin 3 [Homo sapiens] 707 0.0 gi|14149631 ring finger protein 112 [Homo sapiens] 86 7e-17 gi|31377634 guanylate binding protein 4 [Homo sapiens] 74 3e-13 gi|148234215 guanylate binding protein 4-like [Homo sapiens] 73 8e-13 gi|197333737 guanylate-binding protein 5 [Homo sapiens] 72 2e-12 gi|16418425 guanylate-binding protein 5 [Homo sapiens] 72 2e-12 gi|112382372 guanylate binding protein 3 [Homo sapiens] 70 5e-12 gi|38327558 guanylate binding protein 2, interferon-inducible [H... 68 2e-11 gi|157671915 guanylate binding protein family, member 6 [Homo sa... 67 6e-11 gi|166706903 guanylate binding protein 1, interferon-inducible, ... 63 9e-10 gi|46593000 GRIP1 associated protein 1 isoform 2 [Homo sapiens] 36 0.086 gi|4758942 septin 4 isoform 1 [Homo sapiens] 32 1.2 gi|17986247 septin 4 isoform 3 [Homo sapiens] 32 1.2 gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] 32 1.2 gi|58331187 T-cell lymphoma invasion and metastasis 2 isoform a ... 30 4.7 gi|32967591 phosducin isoform a [Homo sapiens] 30 6.1 gi|12408668 phosducin isoform b [Homo sapiens] 30 6.1 gi|115511020 Smg-6 homolog, nonsense mediated mRNA decay factor ... 30 6.1 gi|23510381 transportin 1 isoform 2 [Homo sapiens] 30 8.0 gi|133925811 transportin 1 isoform 1 [Homo sapiens] 30 8.0 gi|164519084 RAB GTPase activating protein 1 [Homo sapiens] 30 8.0 >gi|208610002 atlastin GTPase 2 isoform 2 [Homo sapiens] Length = 583 Score = 1181 bits (3055), Expect = 0.0 Identities = 583/583 (100%), Positives = 583/583 (100%) Query: 1 MAEGDEAARGQQPHQGLWRRRRTSDPSAAVNHVSSTTSLGENYEDDDLVNSDEVMKKPCP 60 MAEGDEAARGQQPHQGLWRRRRTSDPSAAVNHVSSTTSLGENYEDDDLVNSDEVMKKPCP Sbjct: 1 MAEGDEAARGQQPHQGLWRRRRTSDPSAAVNHVSSTTSLGENYEDDDLVNSDEVMKKPCP 60 Query: 61 VQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYN 120 VQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYN Sbjct: 61 VQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYN 120 Query: 121 KDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDS 180 KDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDS Sbjct: 121 KDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDS 180 Query: 181 QSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLM 240 QSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLM Sbjct: 181 QSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLM 240 Query: 241 FLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPG 300 FLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPG Sbjct: 241 FLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPG 300 Query: 301 LKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYI 360 LKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYI Sbjct: 301 LKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYI 360 Query: 361 KIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLD 420 KIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLD Sbjct: 361 KIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLD 420 Query: 421 LKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFA 480 LKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFA Sbjct: 421 LKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFA 480 Query: 481 VMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIGTVIDQIAET 540 VMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIGTVIDQIAET Sbjct: 481 VMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIGTVIDQIAET 540 Query: 541 LWEQVLKPLGDNLMEENIRQSVTNSIKAGLTDQVSHHARLKTD 583 LWEQVLKPLGDNLMEENIRQSVTNSIKAGLTDQVSHHARLKTD Sbjct: 541 LWEQVLKPLGDNLMEENIRQSVTNSIKAGLTDQVSHHARLKTD 583 >gi|208610000 atlastin GTPase 2 isoform 1 [Homo sapiens] Length = 579 Score = 1109 bits (2868), Expect = 0.0 Identities = 547/571 (95%), Positives = 557/571 (97%) Query: 1 MAEGDEAARGQQPHQGLWRRRRTSDPSAAVNHVSSTTSLGENYEDDDLVNSDEVMKKPCP 60 MAEGDEAARGQQPHQGLWRRRRTSDPSAAVNHVSSTTSLGENYEDDDLVNSDEVMKKPCP Sbjct: 1 MAEGDEAARGQQPHQGLWRRRRTSDPSAAVNHVSSTTSLGENYEDDDLVNSDEVMKKPCP 60 Query: 61 VQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYN 120 VQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYN Sbjct: 61 VQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYN 120 Query: 121 KDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDS 180 KDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDS Sbjct: 121 KDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDS 180 Query: 181 QSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLM 240 QSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLM Sbjct: 181 QSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLM 240 Query: 241 FLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPG 300 FLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPG Sbjct: 241 FLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPG 300 Query: 301 LKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYI 360 LKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYI Sbjct: 301 LKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYI 360 Query: 361 KIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLD 420 KIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLD Sbjct: 361 KIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLD 420 Query: 421 LKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFA 480 LKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFA Sbjct: 421 LKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFA 480 Query: 481 VMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIGTVIDQIAET 540 VMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIGTVIDQIAET Sbjct: 481 VMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIGTVIDQIAET 540 Query: 541 LWEQVLKPLGDNLMEENIRQSVTNSIKAGLT 571 LWEQV L + + ++++++ + L+ Sbjct: 541 LWEQVFSKLFEVTRRRMVHRALSSAQRQRLS 571 >gi|189181742 atlastin GTPase 1 isoform b [Homo sapiens] Length = 553 Score = 761 bits (1964), Expect = 0.0 Identities = 357/498 (71%), Positives = 434/498 (87%), Gaps = 1/498 (0%) Query: 52 DEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLL 111 +E +KK PVQ+++ +DDH+FELDE AL +ILL E +RD +V VSVAGAFRKGKSFL+ Sbjct: 26 EEPVKKAGPVQVLIV-KDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLM 84 Query: 112 DFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLL 171 DFMLRYMYN++S W+G NEPLTGF+WRGG ERETTGIQ+W+E+F+I++P+G KVAVLL Sbjct: 85 DFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEIFLINKPDGKKVAVLL 144 Query: 172 MDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEI 231 MDTQG FDSQST++D ATVFALSTM SS+QVYNLSQN+QEDDLQHLQLFTEYGRLAMEE Sbjct: 145 MDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEET 204 Query: 232 YQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNL 291 + KPFQ+L+FL+RDWS+PYE SYG +GG +FLEKRL+V NQHEELQNVRKHIH+CF+N+ Sbjct: 205 FLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNI 264 Query: 292 GCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRD 351 CFLLPHPGLKVATNP+FDG+LK+ID++F + L+ L+P LL+PE+L KEI+G+K+TCR Sbjct: 265 SCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRG 324 Query: 352 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAP 411 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVA A+DTY K ME++CGGDKP++AP Sbjct: 325 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAP 384 Query: 412 SDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYA 471 +DL+ KHL LKE ++K FR VKKMGG+EF RRY QLE+EI+E Y +IKHND KNIF+A Sbjct: 385 NDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSKNIFHA 444 Query: 472 ARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIG 531 ARTPATLF V+F Y+I+G+TGFIGL+ IA LCN++MGL LI LCTWAY++YSGE+RE+G Sbjct: 445 ARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCTWAYIRYSGEYRELG 504 Query: 532 TVIDQIAETLWEQVLKPL 549 VIDQ+A LW+Q L L Sbjct: 505 AVIDQVAAALWDQALYKL 522 >gi|74024917 atlastin GTPase 1 isoform b [Homo sapiens] Length = 553 Score = 761 bits (1964), Expect = 0.0 Identities = 357/498 (71%), Positives = 434/498 (87%), Gaps = 1/498 (0%) Query: 52 DEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLL 111 +E +KK PVQ+++ +DDH+FELDE AL +ILL E +RD +V VSVAGAFRKGKSFL+ Sbjct: 26 EEPVKKAGPVQVLIV-KDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLM 84 Query: 112 DFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLL 171 DFMLRYMYN++S W+G NEPLTGF+WRGG ERETTGIQ+W+E+F+I++P+G KVAVLL Sbjct: 85 DFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEIFLINKPDGKKVAVLL 144 Query: 172 MDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEI 231 MDTQG FDSQST++D ATVFALSTM SS+QVYNLSQN+QEDDLQHLQLFTEYGRLAMEE Sbjct: 145 MDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEET 204 Query: 232 YQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNL 291 + KPFQ+L+FL+RDWS+PYE SYG +GG +FLEKRL+V NQHEELQNVRKHIH+CF+N+ Sbjct: 205 FLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNI 264 Query: 292 GCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRD 351 CFLLPHPGLKVATNP+FDG+LK+ID++F + L+ L+P LL+PE+L KEI+G+K+TCR Sbjct: 265 SCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRG 324 Query: 352 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAP 411 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVA A+DTY K ME++CGGDKP++AP Sbjct: 325 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAP 384 Query: 412 SDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYA 471 +DL+ KHL LKE ++K FR VKKMGG+EF RRY QLE+EI+E Y +IKHND KNIF+A Sbjct: 385 NDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSKNIFHA 444 Query: 472 ARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIG 531 ARTPATLF V+F Y+I+G+TGFIGL+ IA LCN++MGL LI LCTWAY++YSGE+RE+G Sbjct: 445 ARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCTWAYIRYSGEYRELG 504 Query: 532 TVIDQIAETLWEQVLKPL 549 VIDQ+A LW+Q L L Sbjct: 505 AVIDQVAAALWDQALYKL 522 >gi|19923445 atlastin GTPase 1 isoform a [Homo sapiens] Length = 558 Score = 759 bits (1959), Expect = 0.0 Identities = 355/493 (72%), Positives = 432/493 (87%), Gaps = 1/493 (0%) Query: 52 DEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLL 111 +E +KK PVQ+++ +DDH+FELDE AL +ILL E +RD +V VSVAGAFRKGKSFL+ Sbjct: 26 EEPVKKAGPVQVLIV-KDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLM 84 Query: 112 DFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLL 171 DFMLRYMYN++S W+G NEPLTGF+WRGG ERETTGIQ+W+E+F+I++P+G KVAVLL Sbjct: 85 DFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEIFLINKPDGKKVAVLL 144 Query: 172 MDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEI 231 MDTQG FDSQST++D ATVFALSTM SS+QVYNLSQN+QEDDLQHLQLFTEYGRLAMEE Sbjct: 145 MDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEET 204 Query: 232 YQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNL 291 + KPFQ+L+FL+RDWS+PYE SYG +GG +FLEKRL+V NQHEELQNVRKHIH+CF+N+ Sbjct: 205 FLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNI 264 Query: 292 GCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRD 351 CFLLPHPGLKVATNP+FDG+LK+ID++F + L+ L+P LL+PE+L KEI+G+K+TCR Sbjct: 265 SCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRG 324 Query: 352 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAP 411 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVA A+DTY K ME++CGGDKP++AP Sbjct: 325 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAP 384 Query: 412 SDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYA 471 +DL+ KHL LKE ++K FR VKKMGG+EF RRY QLE+EI+E Y +IKHND KNIF+A Sbjct: 385 NDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSKNIFHA 444 Query: 472 ARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIG 531 ARTPATLF V+F Y+I+G+TGFIGL+ IA LCN++MGL LI LCTWAY++YSGE+RE+G Sbjct: 445 ARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCTWAYIRYSGEYRELG 504 Query: 532 TVIDQIAETLWEQ 544 VIDQ+A LW+Q Sbjct: 505 AVIDQVAAALWDQ 517 >gi|45827806 atlastin 3 [Homo sapiens] Length = 541 Score = 707 bits (1825), Expect = 0.0 Identities = 339/517 (65%), Positives = 421/517 (81%), Gaps = 6/517 (1%) Query: 51 SDEVMK--KPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKS 108 +D+ M+ KP PVQ+VL +D H+FELDE+AL ILLQ+HIRDL++VVVSVAGAFRKGKS Sbjct: 15 ADDAMESSKPGPVQVVLVQKDQHSFELDEKALASILLQDHIRDLDVVVVSVAGAFRKGKS 74 Query: 109 FLLDFMLRYMYNKDSQ---SWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGT 165 F+LDFMLRY+Y++ +W+G EPLTGF+WRGG + ETTGIQ+W+EVF +++P G Sbjct: 75 FILDFMLRYLYSQKESGHSNWLGDPEEPLTGFSWRGGSDPETTGIQIWSEVFTVEKPGGK 134 Query: 166 KVAVLLMDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGR 225 KVAV+LMDTQGAFDSQST+KDCAT+FALSTMTSSVQ+YNLSQNIQEDDLQ LQLFTEYGR Sbjct: 135 KVAVVLMDTQGAFDSQSTVKDCATIFALSTMTSSVQIYNLSQNIQEDDLQQLQLFTEYGR 194 Query: 226 LAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIH 285 LAM+EI+QKPFQTLMFL+RDWS+PYE+SYGL+GG FL+KRLQVK++QHEE+QNVR HIH Sbjct: 195 LAMDEIFQKPFQTLMFLVRDWSFPYEYSYGLQGGMAFLDKRLQVKEHQHEEIQNVRNHIH 254 Query: 286 NCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGS 345 +CFS++ CFLLPHPGL+VAT+P FDG+LKDI +FK +L+ L+P +L P L+EKEI+GS Sbjct: 255 SCFSDVTCFLLPHPGLQVATSPDFDGKLKDIAGEFKEQLQALIPYVLNPSKLMEKEINGS 314 Query: 346 KVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGD 405 KVTCR L+EYFKAYIKIYQGE+LPHPKSMLQATAEANNLAA A A+D Y +ME+VCGG+ Sbjct: 315 KVTCRGLLEYFKAYIKIYQGEDLPHPKSMLQATAEANNLAAAASAKDIYYNNMEEVCGGE 374 Query: 406 KPYIAPSDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDG 465 KPY++P LE KH + K++A+ F+ KKMGG +F RYQ +LE EI+E Y NF KHN Sbjct: 375 KPYLSPDILEEKHCEFKQLALDHFKKTKKMGGKDFSFRYQQELEEEIKELYENFCKHNGS 434 Query: 466 KNIFYAARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSG 525 KN+F RTPA LF + A+YI SGLTGFIGL +A L N ++GL LI L TW Y++YSG Sbjct: 435 KNVFSTFRTPAVLFTGIVALYIASGLTGFIGLEVVAQLFNCMVGLLLIALLTWGYIRYSG 494 Query: 526 EFREIGTVIDQIAETLWEQVLKPLGDNLMEENIRQSV 562 ++RE+G ID A + EQ +G N + +R +V Sbjct: 495 QYRELGGAIDFGAAYVLEQASSHIG-NSTQATVRDAV 530 >gi|14149631 ring finger protein 112 [Homo sapiens] Length = 632 Score = 86.3 bits (212), Expect = 7e-17 Identities = 71/248 (28%), Positives = 116/248 (46%), Gaps = 17/248 (6%) Query: 79 ALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSW--IGGNNEPLTG 136 A+ + L RD + +++V G GKSFLL+ +L+ + +S G L G Sbjct: 154 AINRCLKHPLARDTPVCLLAVLGEQHSGKSFLLNHLLQGLPGLESGEGGRPRGGEASLQG 213 Query: 137 FTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDSQSTIKDCATVFALSTM 196 W G GI +W+ F++ + G KVAV L+DT A + + + + AL+TM Sbjct: 214 CRW--GANGLARGIWMWSHPFLLGK-EGKKVAVFLVDTGDAMSPELSRETRIKLCALTTM 270 Query: 197 TSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGL 256 SS Q+ + SQ +++ DL +L++F + + P Q L L+RD S+P + G Sbjct: 271 LSSYQILSTSQELKDTDLDYLEMFVHVAEVMGKHYGMVPIQHLDLLVRDSSHPNKAGQGH 330 Query: 257 EGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDI 316 G + +RL + + +EL ++ C LLP PG + N D Sbjct: 331 VGN---IFQRLSGRYPKVQELLQGKR--------ARCCLLPAPGRR-RMNQGHASPGGDT 378 Query: 317 DEDFKREL 324 D+DF+ L Sbjct: 379 DDDFRHLL 386 >gi|31377634 guanylate binding protein 4 [Homo sapiens] Length = 640 Score = 74.3 bits (181), Expect = 3e-13 Identities = 101/438 (23%), Positives = 181/438 (41%), Gaps = 53/438 (12%) Query: 51 SDEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFL 110 S+ +M P I L + ++ +ALE + + I +VVV++ G +R GKS+L Sbjct: 18 SESIMMAP----ICLVENQEEQLTVNSKALE---ILDKISQ-PVVVVAIVGLYRTGKSYL 69 Query: 111 LDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVL 170 ++ + G N GF + ET GI +W V + +PN T V Sbjct: 70 MNRLA------------GKRN----GFPLGSTVQSETKGIWMWC-VPHLSKPNHTLV--- 109 Query: 171 LMDTQGAFD-SQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAME 229 L+DT+G D +S K+ + +FAL+ + SS VYN I L+ L TE L Sbjct: 110 LLDTEGLGDVEKSNPKNDSWIFALAVLLSSSFVYNSVSTINHQALEQLHYVTELAELIRA 169 Query: 230 EIYQKP------------FQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEEL 277 + +P F ++ +RD++ + ++LE L++ ++ ++ Sbjct: 170 KSCPRPDEAEDSSEFASFFPDFIWTVRDFTLELKLDGNPITEDEYLENALKLIPGKNPKI 229 Query: 278 QN---VRKHIHNCFSNLGCFLLPHP-GLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLA 333 QN R+ I + F CF+ P K N + ++++ F + N + Sbjct: 230 QNSNMPRECIRHFFRKRKCFVFDRPTNDKQYLNHMDEVPEENLERHFLMQSDNFCSYIFT 289 Query: 334 PENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDT 393 + G VT + L Y+ +P ++ + A A+ N AAV A D Sbjct: 290 HAK-TKTLREGIIVTGKRLGTLVVTYVDAINSGAVPCLENAVTALAQLENPAAVQRAADH 348 Query: 394 YCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSV-KKMGGDEFCRRYQDQLEAEI 452 Y + M Q P+D ++ LD+ ++ +V + + +Q +L I Sbjct: 349 YSQQMAQ------QLRLPTDTLQELLDVHAACEREAIAVFMEHSFKDENHEFQKKLVDTI 402 Query: 453 EETYANFIKHNDGKNIFY 470 E+ +F+ N+ + Y Sbjct: 403 EKKKGDFVLQNEEASAKY 420 >gi|148234215 guanylate binding protein 4-like [Homo sapiens] Length = 638 Score = 72.8 bits (177), Expect = 8e-13 Identities = 89/395 (22%), Positives = 163/395 (41%), Gaps = 45/395 (11%) Query: 94 IVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVW 153 +VVV++ G +R GKS+L+ NK + G N+ GF + ET GI +W Sbjct: 38 VVVVAIVGLYRTGKSYLM--------NK-----LAGKNK---GFPLGCTVKSETKGIWMW 81 Query: 154 NEVFVIDRPNGTKVAVLLMDTQGAFDSQ-STIKDCATVFALSTMTSSVQVYNLSQNIQED 212 + P+ ++L+DT+G D + S K + +FAL+ + SS VYN I Sbjct: 82 ----CVPHPSKPNHTLILLDTEGLGDMEKSDPKSDSWIFALAVLLSSSFVYNSMGTINHQ 137 Query: 213 DLQHLQLFTEYGRLAMEEIYQKP------------FQTLMFLIRDWSYPYEHSYGLEGGK 260 L+ L TE L + +P F ++ +RD++ + Sbjct: 138 ALEQLHYVTELTELIRAKSCPRPDEVEDSSEFVSFFPDFIWTVRDFTLELKLDGHPITED 197 Query: 261 QFLEKRLQVKQNQHEELQN---VRKHIHNCFSNLGCFLLPHP-GLKVATNPSFDGRLKDI 316 ++LE L++ ++ ++QN R+ I + F CF+ P K + R + Sbjct: 198 EYLENALKLISGKNPQIQNSNKPREWIRHFFPKQKCFVFDRPINDKKLLLHVEEVREDQL 257 Query: 317 DEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQ 376 D +F+ + N + + G VT L + Y+ P ++ + Sbjct: 258 DSNFQMQSENFCSYIFTHAK-TKTLREGILVTGNRLGMLVETYLDAINSGATPCLENAMA 316 Query: 377 ATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSV-KKM 435 A+ N AAV A + Y + M Q P+D ++ LD+ V ++ +V + Sbjct: 317 VLAQCENSAAVQRAANHYSQQMAQ------QVRFPTDTLQELLDVHAVCEREAIAVFMEY 370 Query: 436 GGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFY 470 + + +Q +L +E+ +F+ N+ + Y Sbjct: 371 SFKDKSQEFQKKLVDTMEKKKEDFVLQNEEASAKY 405 >gi|197333737 guanylate-binding protein 5 [Homo sapiens] Length = 586 Score = 71.6 bits (174), Expect = 2e-12 Identities = 92/389 (23%), Positives = 163/389 (41%), Gaps = 48/389 (12%) Query: 94 IVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVW 153 +VVV++ G +R GKS+L+ NK + G N+ GF+ + T GI +W Sbjct: 38 VVVVAIVGLYRTGKSYLM--------NK-----LAGKNK---GFSVASTVQSHTKGIWIW 81 Query: 154 NEVFVIDRPNGTKVAVLLMDTQGAFD-SQSTIKDCATVFALSTMTSSVQVYNLSQNIQED 212 + PN ++L+DT+G D ++ K+ +FAL+ + SS VYN I + Sbjct: 82 ----CVPHPNWPNHTLVLLDTEGLGDVEKADNKNDIQIFALALLLSSTFVYNTVNKIDQG 137 Query: 213 DLQHLQLFTEYGRLAME------EIYQKP------FQTLMFLIRDWSYPYEHSYGLEGGK 260 + L TE L + + P F L++ +RD+ E L Sbjct: 138 AIDLLHNVTELTDLLKARNSPDLDRVEDPADSASFFPDLVWTLRDFCLGLEIDGQLVTPD 197 Query: 261 QFLEKRLQVKQNQHEELQNV---RKHIHNCFSNLGCFL--LPHPGLKVATNPSFDGRLKD 315 ++LE L+ KQ + +QN R I F CF+ LP K+A + + Sbjct: 198 EYLENSLRPKQGSDQRVQNFNLPRLCIQKFFPKKKCFIFDLPAHQKKLAQLETLPD--DE 255 Query: 316 IDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSML 375 ++ +F +++ + + ++ + G V L Y+ +LP ++ + Sbjct: 256 LEPEFVQQVTEFCSYIFS-HSMTKTLPGGIMVNGSRLKNLVLTYVNAISSGDLPCIENAV 314 Query: 376 QATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSV-KK 434 A A+ N AAV A Y + M G K + P + ++ LDL + ++ V K Sbjct: 315 LALAQRENSAAVQKAIAHYDQQM-----GQKVQL-PMETLQELLDLHRTSEREAIEVFMK 368 Query: 435 MGGDEFCRRYQDQLEAEIEETYANFIKHN 463 + + +Q +LE ++ + K N Sbjct: 369 NSFKDVDQSFQKELETLLDAKQNDICKRN 397 >gi|16418425 guanylate-binding protein 5 [Homo sapiens] Length = 586 Score = 71.6 bits (174), Expect = 2e-12 Identities = 92/389 (23%), Positives = 163/389 (41%), Gaps = 48/389 (12%) Query: 94 IVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVW 153 +VVV++ G +R GKS+L+ NK + G N+ GF+ + T GI +W Sbjct: 38 VVVVAIVGLYRTGKSYLM--------NK-----LAGKNK---GFSVASTVQSHTKGIWIW 81 Query: 154 NEVFVIDRPNGTKVAVLLMDTQGAFD-SQSTIKDCATVFALSTMTSSVQVYNLSQNIQED 212 + PN ++L+DT+G D ++ K+ +FAL+ + SS VYN I + Sbjct: 82 ----CVPHPNWPNHTLVLLDTEGLGDVEKADNKNDIQIFALALLLSSTFVYNTVNKIDQG 137 Query: 213 DLQHLQLFTEYGRLAME------EIYQKP------FQTLMFLIRDWSYPYEHSYGLEGGK 260 + L TE L + + P F L++ +RD+ E L Sbjct: 138 AIDLLHNVTELTDLLKARNSPDLDRVEDPADSASFFPDLVWTLRDFCLGLEIDGQLVTPD 197 Query: 261 QFLEKRLQVKQNQHEELQNV---RKHIHNCFSNLGCFL--LPHPGLKVATNPSFDGRLKD 315 ++LE L+ KQ + +QN R I F CF+ LP K+A + + Sbjct: 198 EYLENSLRPKQGSDQRVQNFNLPRLCIQKFFPKKKCFIFDLPAHQKKLAQLETLPD--DE 255 Query: 316 IDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSML 375 ++ +F +++ + + ++ + G V L Y+ +LP ++ + Sbjct: 256 LEPEFVQQVTEFCSYIFS-HSMTKTLPGGIMVNGSRLKNLVLTYVNAISSGDLPCIENAV 314 Query: 376 QATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSV-KK 434 A A+ N AAV A Y + M G K + P + ++ LDL + ++ V K Sbjct: 315 LALAQRENSAAVQKAIAHYDQQM-----GQKVQL-PMETLQELLDLHRTSEREAIEVFMK 368 Query: 435 MGGDEFCRRYQDQLEAEIEETYANFIKHN 463 + + +Q +LE ++ + K N Sbjct: 369 NSFKDVDQSFQKELETLLDAKQNDICKRN 397 >gi|112382372 guanylate binding protein 3 [Homo sapiens] Length = 595 Score = 70.1 bits (170), Expect = 5e-12 Identities = 92/390 (23%), Positives = 166/390 (42%), Gaps = 50/390 (12%) Query: 94 IVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVW 153 +VVV++ G +R GKS+L+ NK + G N+ GF+ + T GI +W Sbjct: 38 VVVVAIVGLYRTGKSYLM--------NK-----LAGKNK---GFSLGSTVKSHTKGIWMW 81 Query: 154 NEVFVIDRPNGTKVAVLLMDTQGAFD-SQSTIKDCATVFALSTMTSSVQVYNLSQNIQED 212 + P + ++L+DT+G D + ++ + +F L+ + SS VYN I + Sbjct: 82 ----CVPHPKKPEHTLVLLDTEGLGDVKKGDNQNDSWIFTLAVLLSSTLVYNSMGTINQQ 137 Query: 213 DLQHLQLFTEYGRLAMEEI------------YQKPFQTLMFLIRDWSYPYEHSYGLEGGK 260 + L TE + + F ++ +RD+S E Sbjct: 138 AMDQLYYVTELTHRIRSKSSPDENENEDSADFVSFFPDFVWTLRDFSLDLEADGQPLTPD 197 Query: 261 QFLEKRLQVKQNQHEELQNV---RKHIHNCFSNLGCFL--LPHPGLKVATNPSFDGRLKD 315 ++LE L++ Q ++ +N R I F CF+ LP K+A ++ Sbjct: 198 EYLEYSLKLTQGTSQKDKNFNLPRLCIRKFFPKKKCFVFDLPIHRRKLAQLEKLQD--EE 255 Query: 316 IDEDFKRELRNLVPLLLAPENLVEKEISGS-KVTCRDLVEYFKAYIKIYQGEELPHPKSM 374 +D +F +++ + + + N K +SG KV L YI +LP ++ Sbjct: 256 LDPEFVQQVADFCSYIFS--NSKTKTLSGGIKVNGPRLESLVLTYINAISRGDLPCMENA 313 Query: 375 LQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSV-K 433 + A A+ N AAV A Y + M G K + P++ ++ LDL V+ ++ V Sbjct: 314 VLALAQIENSAAVQKAIAHYDQQM-----GQKVQL-PAETLQELLDLHRVSEREATEVYM 367 Query: 434 KMGGDEFCRRYQDQLEAEIEETYANFIKHN 463 K + +Q +L A++++ +F K N Sbjct: 368 KNSFKDVDHLFQKKLAAQLDKKRDDFCKQN 397 >gi|38327558 guanylate binding protein 2, interferon-inducible [Homo sapiens] Length = 591 Score = 68.2 bits (165), Expect = 2e-11 Identities = 87/387 (22%), Positives = 160/387 (41%), Gaps = 44/387 (11%) Query: 94 IVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVW 153 +VVV++ G +R GKS+L++ + G N GF+ + T GI +W Sbjct: 38 VVVVAIVGLYRTGKSYLMNKL------------AGKKN----GFSLGSTVKSHTKGIWMW 81 Query: 154 NEVFVIDRPNGTKVAVLLMDTQGAFD-SQSTIKDCATVFALSTMTSSVQVYNLSQNIQED 212 + P + ++L+DT+G D + ++ + +FAL+ + SS VYN I + Sbjct: 82 ----CVPHPKKPEHTLVLLDTEGLGDIEKGDNENDSWIFALAILLSSTFVYNSMGTINQQ 137 Query: 213 DLQHLQLFTEY----------GRLAMEEI--YQKPFQTLMFLIRDWSYPYEHSYGLEGGK 260 + L TE G ++++ + F ++ +RD++ E Sbjct: 138 AMDQLHYVTELTDRIKANSSPGNNSVDDSADFVSFFPAFVWTLRDFTLELEVDGEPITAD 197 Query: 261 QFLEKRLQVKQ---NQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDID 317 +LE L++++ + + + R I F CF+ P K + ++++ Sbjct: 198 DYLELSLKLRKGTDKKSKSFNDPRLCIRKFFPKRKCFVFDWPAPKKYLAHLEQLKEEELN 257 Query: 318 EDFKRELRNLVPLLLAPENLVEKEISGS-KVTCRDLVEYFKAYIKIYQGEELPHPKSMLQ 376 DF ++ +L+ N+ K +SG V L Y+ +LP ++ + Sbjct: 258 PDFIEQVAEFCSYILSHSNV--KTLSGGIPVNGPRLESLVLTYVNAISSGDLPCMENAVL 315 Query: 377 ATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSVKKMG 436 A A+ N AAV A Y + M Q P +L H D + AI+ F K Sbjct: 316 ALAQIENSAAVEKAIAHYEQQMGQKV--QLPTETLQELLDLHRDSEREAIEVF---MKNS 370 Query: 437 GDEFCRRYQDQLEAEIEETYANFIKHN 463 + + +Q +L A++E +F K N Sbjct: 371 FKDVDQMFQRKLGAQLEARRDDFCKQN 397 >gi|157671915 guanylate binding protein family, member 6 [Homo sapiens] Length = 633 Score = 66.6 bits (161), Expect = 6e-11 Identities = 82/349 (23%), Positives = 141/349 (40%), Gaps = 44/349 (12%) Query: 75 LDEEALEQILL-QEHIRDLN-----IVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIG 128 L E EQ+L+ Q+ I+ L +VVV++ G +R GKS+L++ + Sbjct: 13 LVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHL-------------A 59 Query: 129 GNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFD-SQSTIKDC 187 G N GF + ET GI +W + P+ ++L+DT+G D + K+ Sbjct: 60 GQNH---GFPLGSTVQSETKGIWMW----CVPHPSKPNHTLVLLDTEGLGDVEKGDPKND 112 Query: 188 ATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKP------------ 235 + +FAL+ + S VYN I L+ L TE L + +P Sbjct: 113 SWIFALAVLLCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSF 172 Query: 236 FQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQN---VRKHIHNCFSNLG 292 F ++ +RD++ + + ++LE L++ Q + +Q R+ I F Sbjct: 173 FPDFLWTVRDFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRK 232 Query: 293 CFLLPHPGLKVATNPSFDG-RLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRD 351 CF+ P + + K +D F +E N+ + + G VT Sbjct: 233 CFVFDRPTNDKDLLANIEKVSEKQLDPKF-QEQTNIFCSYIFTHARTKTLREGITVTGNR 291 Query: 352 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQ 400 L Y++ +P ++ + A+ N AAV A D Y + M Q Sbjct: 292 LGTLAVTYVEAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQ 340 >gi|166706903 guanylate binding protein 1, interferon-inducible, 67kDa [Homo sapiens] Length = 592 Score = 62.8 bits (151), Expect = 9e-10 Identities = 91/390 (23%), Positives = 162/390 (41%), Gaps = 48/390 (12%) Query: 94 IVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVW 153 +VVV++ G +R GKS+L+ NK + G + GF+ + T GI +W Sbjct: 38 MVVVAIVGLYRTGKSYLM--------NK-----LAGKKK---GFSLGSTVQSHTKGIWMW 81 Query: 154 NEVFVIDRPNGTKVAVLLMDTQGAFD-SQSTIKDCATVFALSTMTSSVQVYNLSQNIQED 212 + P ++L+DT+G D + ++ + +FAL+ + SS VYN I + Sbjct: 82 ----CVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAVLLSSTFVYNSIGTINQQ 137 Query: 213 DLQHLQLFTEY--------------GRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEG 258 + L TE + + F ++ +RD+S E Sbjct: 138 AMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVWTLRDFSLDLEADGQPLT 197 Query: 259 GKQFLEKRLQVKQ--NQHEELQNV-RKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKD 315 ++L L++K+ +Q +E N+ R I F CF+ P + + ++ Sbjct: 198 PDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDRPVHRRKLAQLEKLQDEE 257 Query: 316 IDEDFKRELRNLVPLLLAPENLVEKEISGS-KVTCRDLVEYFKAYIKIYQGEELPHPKSM 374 +D +F +++ + + + N K +SG +V L Y+ +LP ++ Sbjct: 258 LDPEFVQQVADFCSYIFS--NSKTKTLSGGIQVNGPRLESLVLTYVNAISSGDLPCMENA 315 Query: 375 LQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQF-RSVK 433 + A A+ N AAV A Y + M Q P +L H D + AI+ F RS Sbjct: 316 VLALAQIENSAAVQKAIAHYEQQMGQKV--QLPTETLQELLDLHRDSEREAIEVFIRSSF 373 Query: 434 KMGGDEFCRRYQDQLEAEIEETYANFIKHN 463 K + +Q +L A++E+ +F K N Sbjct: 374 K----DVDHLFQKELAAQLEKKRDDFCKQN 399 >gi|46593000 GRIP1 associated protein 1 isoform 2 [Homo sapiens] Length = 625 Score = 36.2 bits (82), Expect = 0.086 Identities = 21/89 (23%), Positives = 40/89 (44%), Gaps = 3/89 (3%) Query: 224 GRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKH 283 G++ E+ + +TL + + + ++G K + E+RL+ + + EELQ+VR Sbjct: 436 GQIREEKARTRELETLQQTVEELQ---AQVHSMDGAKGWFERRLKEAEGKEEELQDVRDQ 492 Query: 284 IHNCFSNLGCFLLPHPGLKVATNPSFDGR 312 + C L LK + DG+ Sbjct: 493 LEQAQEERDCHLKTISSLKQEVKDTVDGQ 521 >gi|4758942 septin 4 isoform 1 [Homo sapiens] Length = 478 Score = 32.3 bits (72), Expect = 1.2 Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 5/59 (8%) Query: 309 FDGRLKDIDEDFKRELR---NLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQ 364 F L+ +D +F + L N+VP+L + L E+ K R+ +E+F IKIYQ Sbjct: 263 FGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFG--IKIYQ 319 >gi|17986247 septin 4 isoform 3 [Homo sapiens] Length = 459 Score = 32.3 bits (72), Expect = 1.2 Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 5/59 (8%) Query: 309 FDGRLKDIDEDFKRELR---NLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQ 364 F L+ +D +F + L N+VP+L + L E+ K R+ +E+F IKIYQ Sbjct: 244 FGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFG--IKIYQ 300 >gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] Length = 1013 Score = 32.3 bits (72), Expect = 1.2 Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 10/98 (10%) Query: 415 ERKHLD--LKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAA 472 ER+ LD KEVA+ + KM +E CR+Y + + A I DG N Sbjct: 18 ERRDLDDLKKEVAMTEH----KMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNAL--T 71 Query: 473 RTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGL 510 P T V F + G + + + A+LC L G+ Sbjct: 72 PPPTTPEWVKFCRQLFGGFSILLWIG--AILCFLAYGI 107 >gi|58331187 T-cell lymphoma invasion and metastasis 2 isoform a [Homo sapiens] Length = 1701 Score = 30.4 bits (67), Expect = 4.7 Identities = 13/29 (44%), Positives = 19/29 (65%) Query: 357 KAYIKIYQGEELPHPKSMLQATAEANNLA 385 + Y+ QG ELP+PKS+L A + + LA Sbjct: 695 RCYLASLQGGELPNPKSLLAAASRPSKLA 723 >gi|32967591 phosducin isoform a [Homo sapiens] Length = 246 Score = 30.0 bits (66), Expect = 6.1 Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 16/107 (14%) Query: 199 SVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEG 258 S+Q Y L +ED+ +Y R M++++QK L F R Y Y LE Sbjct: 73 SIQEYELIHKEKEDE----NCLRKYRRQCMQDMHQK----LSFGPR-----YGFVYELET 119 Query: 259 GKQFL---EKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLK 302 GKQFL EK L++ ++ K S+L C +P +K Sbjct: 120 GKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVK 166 >gi|12408668 phosducin isoform b [Homo sapiens] Length = 194 Score = 30.0 bits (66), Expect = 6.1 Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 16/107 (14%) Query: 199 SVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEG 258 S+Q Y L +ED+ +Y R M++++QK L F R Y Y LE Sbjct: 21 SIQEYELIHKEKEDE----NCLRKYRRQCMQDMHQK----LSFGPR-----YGFVYELET 67 Query: 259 GKQFL---EKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLK 302 GKQFL EK L++ ++ K S+L C +P +K Sbjct: 68 GKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVK 114 >gi|115511020 Smg-6 homolog, nonsense mediated mRNA decay factor [Homo sapiens] Length = 1419 Score = 30.0 bits (66), Expect = 6.1 Identities = 39/163 (23%), Positives = 67/163 (41%), Gaps = 25/163 (15%) Query: 306 NPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDL--VEYFKAYIKIY 363 +P D L ++ED R L VPLL AP++ E + KV D V K +++ Sbjct: 1081 DPDDDLTLLILEED--RLLSGFVPLLAAPQDPCYVEKTSDKVIAADCKRVTVLKYFLEAL 1138 Query: 364 QGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCG----GDKPYIAPSDLERK-- 417 G+E P + +VA DT K M G ++ + D E Sbjct: 1139 CGQEEP------LLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSE 1192 Query: 418 ------HLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEE 454 D++E+ K+ +K+ + R Q++++A +E+ Sbjct: 1193 AEGSGGEDDIRELRAKKLALARKIAEQQ---RRQEKIQAVLED 1232 >gi|23510381 transportin 1 isoform 2 [Homo sapiens] Length = 890 Score = 29.6 bits (65), Expect = 8.0 Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 6/58 (10%) Query: 402 CGGDKPYIAPSDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANF 459 C +I P D DL+++ K K GDE RR+ DQ ++E A F Sbjct: 836 CDAVASWINPKD------DLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAF 887 >gi|133925811 transportin 1 isoform 1 [Homo sapiens] Length = 898 Score = 29.6 bits (65), Expect = 8.0 Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 6/58 (10%) Query: 402 CGGDKPYIAPSDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANF 459 C +I P D DL+++ K K GDE RR+ DQ ++E A F Sbjct: 844 CDAVASWINPKD------DLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAF 895 >gi|164519084 RAB GTPase activating protein 1 [Homo sapiens] Length = 1069 Score = 29.6 bits (65), Expect = 8.0 Identities = 19/75 (25%), Positives = 40/75 (53%), Gaps = 3/75 (4%) Query: 438 DEFCRRYQDQ--LEAEIEETYANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFI 495 D C+ YQ + ++ I + Y +F+ + ++ YA++ TLF F +Y++ + + Sbjct: 690 DLHCKFYQLERLMQEYIPDLYNHFLDISLEAHM-YASQWFLTLFTAKFPLYMVFHIIDLL 748 Query: 496 GLNSIAVLCNLVMGL 510 I+V+ N+ +GL Sbjct: 749 LCEGISVIFNVALGL 763 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,643,742 Number of Sequences: 37866 Number of extensions: 955190 Number of successful extensions: 2430 Number of sequences better than 10.0: 26 Number of HSP's better than 10.0 without gapping: 9 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 2391 Number of HSP's gapped (non-prelim): 31 length of query: 583 length of database: 18,247,518 effective HSP length: 108 effective length of query: 475 effective length of database: 14,157,990 effective search space: 6725045250 effective search space used: 6725045250 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.