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Search of human proteins with 207113162
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform
e [Homo sapiens]
(1451 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 2783 0.0
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 2776 0.0
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 2758 0.0
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 2382 0.0
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 2376 0.0
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 1822 0.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 162 2e-39
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 149 2e-35
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 124 9e-28
gi|150170670 piccolo isoform 2 [Homo sapiens] 122 2e-27
gi|150378539 piccolo isoform 1 [Homo sapiens] 122 2e-27
gi|91982772 mucin 17 [Homo sapiens] 119 2e-26
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 116 2e-25
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 116 2e-25
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 115 3e-25
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 114 5e-25
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 114 5e-25
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 104 7e-22
gi|112821681 G protein-regulated inducer of neurite outgrowth 1 ... 104 7e-22
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 103 2e-21
gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 100 1e-20
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 99 2e-20
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 97 9e-20
gi|110832843 TBP-associated factor 4 [Homo sapiens] 96 3e-19
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 95 4e-19
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 91 6e-18
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 91 1e-17
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] 91 1e-17
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] 91 1e-17
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] 91 1e-17
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 2783 bits (7213), Expect = 0.0
Identities = 1451/1451 (100%), Positives = 1451/1451 (100%)
Query: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG
Sbjct: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
Query: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
Query: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP
Sbjct: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
Query: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP
Sbjct: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
Query: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV
Sbjct: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
Query: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL
Sbjct: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
Query: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Query: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE
Sbjct: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
Query: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK
Sbjct: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
Query: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK
Sbjct: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
Query: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR
Sbjct: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
Query: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK
Sbjct: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
Query: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ
Sbjct: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
Query: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL
Sbjct: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
Query: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL
Sbjct: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
Query: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI
Sbjct: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
Query: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN
Sbjct: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
Query: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQ 1080
VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQ
Sbjct: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQ 1080
Query: 1081 AKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPS 1140
AKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPS
Sbjct: 1081 AKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPS 1140
Query: 1141 RTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAA 1200
RTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAA
Sbjct: 1141 RTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAA 1200
Query: 1201 KDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQ 1260
KDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQ
Sbjct: 1201 KDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQ 1260
Query: 1261 CLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAAR 1320
CLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAAR
Sbjct: 1261 CLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAAR 1320
Query: 1321 TPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEP 1380
TPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEP
Sbjct: 1321 TPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEP 1380
Query: 1381 EEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKK 1440
EEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKK
Sbjct: 1381 EEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKK 1440
Query: 1441 KKKKKTAEQTV 1451
KKKKKTAEQTV
Sbjct: 1441 KKKKKTAEQTV 1451
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 2776 bits (7197), Expect = 0.0
Identities = 1450/1451 (99%), Positives = 1450/1451 (99%), Gaps = 1/1451 (0%)
Query: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG
Sbjct: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
Query: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
Query: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP
Sbjct: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
Query: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP
Sbjct: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
Query: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV
Sbjct: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
Query: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL
Sbjct: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
Query: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Query: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE
Sbjct: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
Query: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK
Sbjct: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
Query: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK
Sbjct: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
Query: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR
Sbjct: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
Query: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK
Sbjct: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
Query: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ
Sbjct: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
Query: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL
Sbjct: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
Query: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL
Sbjct: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
Query: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI
Sbjct: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
Query: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN
Sbjct: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
Query: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQ 1080
VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQ
Sbjct: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQ 1080
Query: 1081 AKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPS 1140
AKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTL GPTPS
Sbjct: 1081 AKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTL-GPTPS 1139
Query: 1141 RTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAA 1200
RTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAA
Sbjct: 1140 RTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAA 1199
Query: 1201 KDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQ 1260
KDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQ
Sbjct: 1200 KDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQ 1259
Query: 1261 CLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAAR 1320
CLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAAR
Sbjct: 1260 CLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAAR 1319
Query: 1321 TPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEP 1380
TPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEP
Sbjct: 1320 TPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEP 1379
Query: 1381 EEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKK 1440
EEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKK
Sbjct: 1380 EEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKK 1439
Query: 1441 KKKKKTAEQTV 1451
KKKKKTAEQTV
Sbjct: 1440 KKKKKTAEQTV 1450
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 2758 bits (7148), Expect = 0.0
Identities = 1450/1489 (97%), Positives = 1450/1489 (97%), Gaps = 39/1489 (2%)
Query: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG
Sbjct: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
Query: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
Query: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP
Sbjct: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
Query: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP
Sbjct: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
Query: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV
Sbjct: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
Query: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL
Sbjct: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
Query: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Query: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE
Sbjct: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
Query: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK
Sbjct: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
Query: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK
Sbjct: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
Query: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR
Sbjct: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
Query: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK
Sbjct: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
Query: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ
Sbjct: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
Query: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL
Sbjct: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
Query: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL
Sbjct: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
Query: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI
Sbjct: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
Query: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN
Sbjct: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
Query: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQ------------------- 1061
VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQ
Sbjct: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1080
Query: 1062 -------------------VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1102
VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP
Sbjct: 1081 AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1140
Query: 1103 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPS 1162
ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTL GPTPSRTETLVEETAAESSEDDVVAPS
Sbjct: 1141 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTL-GPTPSRTETLVEETAAESSEDDVVAPS 1199
Query: 1163 QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK 1222
QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK
Sbjct: 1200 QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK 1259
Query: 1223 TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL 1282
TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL
Sbjct: 1260 TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL 1319
Query: 1283 TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP 1342
TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP
Sbjct: 1320 TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP 1379
Query: 1343 EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK 1402
EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK
Sbjct: 1380 EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK 1439
Query: 1403 KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1451
KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV
Sbjct: 1440 KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1488
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 2382 bits (6174), Expect = 0.0
Identities = 1286/1489 (86%), Positives = 1308/1489 (87%), Gaps = 115/1489 (7%)
Query: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG
Sbjct: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
Query: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
RKRKAEEDAALQAKKTRVSDPISTSESSEEE
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEE----------------------------- 91
Query: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
E+A+AET KA P T +++L P E + +ETE+ G
Sbjct: 92 --EEAEAETAKAT--------PRLASTNSSVLGADLPSSMKEKAK-----AETEKAGKT- 135
Query: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
+S + + + GK K A+ A++ E+ + P
Sbjct: 136 ---------------GNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
Query: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
A G K G + + E+ S SS+E T +VKASEKILQV
Sbjct: 181 AFGAAA------KPGMVSAGQADSSSEDTSSSSDE-----------TDVEVKASEKILQV 223
Query: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL
Sbjct: 224 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 283
Query: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE
Sbjct: 284 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 343
Query: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE
Sbjct: 344 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 403
Query: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK
Sbjct: 404 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 463
Query: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK
Sbjct: 464 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 523
Query: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR
Sbjct: 524 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 583
Query: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK
Sbjct: 584 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 643
Query: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ
Sbjct: 644 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 703
Query: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL
Sbjct: 704 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 763
Query: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL
Sbjct: 764 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 823
Query: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI
Sbjct: 824 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 883
Query: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN
Sbjct: 884 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 943
Query: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQ------------------- 1061
VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQ
Sbjct: 944 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1003
Query: 1062 -------------------VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1102
VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP
Sbjct: 1004 AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1063
Query: 1103 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPS 1162
ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPS
Sbjct: 1064 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPS 1123
Query: 1163 QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK 1222
QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK
Sbjct: 1124 QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK 1183
Query: 1223 TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL 1282
TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL
Sbjct: 1184 TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL 1243
Query: 1283 TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP 1342
TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP
Sbjct: 1244 TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP 1303
Query: 1343 EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK 1402
EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK
Sbjct: 1304 EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK 1363
Query: 1403 KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1451
KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV
Sbjct: 1364 KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1412
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 2376 bits (6158), Expect = 0.0
Identities = 1285/1489 (86%), Positives = 1307/1489 (87%), Gaps = 116/1489 (7%)
Query: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG
Sbjct: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
Query: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
RKRKAEEDAALQAKKTRVSDPISTSESSEEE
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEE----------------------------- 91
Query: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
E+A+AET KA P T +++L P E + +ETE+ G
Sbjct: 92 --EEAEAETAKAT--------PRLASTNSSVLGADLPSSMKEKAK-----AETEKAGKT- 135
Query: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
+S + + + GK K A+ A++ E+ + P
Sbjct: 136 ---------------GNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
Query: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
A G K G + + E+ S SS+E T +VKASEKILQV
Sbjct: 181 AFGAAA------KPGMVSAGQADSSSEDTSSSSDE-----------TDVEVKASEKILQV 223
Query: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL
Sbjct: 224 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 283
Query: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE
Sbjct: 284 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 343
Query: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE
Sbjct: 344 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 403
Query: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK
Sbjct: 404 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 463
Query: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK
Sbjct: 464 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 523
Query: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR
Sbjct: 524 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 583
Query: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK
Sbjct: 584 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 643
Query: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ
Sbjct: 644 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 703
Query: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL
Sbjct: 704 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 763
Query: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL
Sbjct: 764 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 823
Query: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI
Sbjct: 824 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 883
Query: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN
Sbjct: 884 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 943
Query: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQ------------------- 1061
VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQ
Sbjct: 944 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVL 1003
Query: 1062 -------------------VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1102
VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP
Sbjct: 1004 AQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1063
Query: 1103 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPS 1162
ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTL GPTPSRTETLVEETAAESSEDDVVAPS
Sbjct: 1064 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTL-GPTPSRTETLVEETAAESSEDDVVAPS 1122
Query: 1163 QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK 1222
QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK
Sbjct: 1123 QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK 1182
Query: 1223 TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL 1282
TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL
Sbjct: 1183 TGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL 1242
Query: 1283 TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP 1342
TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP
Sbjct: 1243 TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP 1302
Query: 1343 EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK 1402
EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK
Sbjct: 1303 EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK 1362
Query: 1403 KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1451
KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV
Sbjct: 1363 KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1411
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
[Homo sapiens]
Length = 958
Score = 1822 bits (4719), Expect = 0.0
Identities = 953/953 (100%), Positives = 953/953 (100%)
Query: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG
Sbjct: 1 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELG 60
Query: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120
Query: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP
Sbjct: 121 MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180
Query: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP
Sbjct: 181 AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240
Query: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV
Sbjct: 241 APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
Query: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL
Sbjct: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
Query: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Query: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE
Sbjct: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
Query: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK
Sbjct: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGK 540
Query: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK
Sbjct: 541 WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
Query: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR
Sbjct: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
Query: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK
Sbjct: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK 720
Query: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ
Sbjct: 721 GLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
Query: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL
Sbjct: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
Query: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL
Sbjct: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
Query: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ 953
APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ
Sbjct: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ 953
Score = 413 bits (1062), Expect = e-115
Identities = 347/973 (35%), Positives = 448/973 (46%), Gaps = 115/973 (11%)
Query: 194 GQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVK 253
G+ + ED + + +T V P SS +E+ A A P ++ V
Sbjct: 60 GRKRKAEEDAALQAKKTRVSD-----PISTSESSEEEEEAEAETAKATP-RLASTNSSVL 113
Query: 254 GGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQV---KASEKILQVRAASAPAKGT 310
G LP + + K E ++ + G+ A T + + K+ K + A + T
Sbjct: 114 GADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSET 173
Query: 311 PGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQ 370
+G+ PA A A AG+ ++SSSE++S S +ET ++ K S K +Q
Sbjct: 174 EEEGSVPA--FGAAAKPGMVSAGQ----ADSSSEDTSSSSDETD-----VEGKPSVKPAQ 222
Query: 371 VGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAG---------KREEDSQSSSEESDSEE 421
V A+S KESP + AAPAP GK G + + G K EE+S+SS E S+SEE
Sbjct: 223 VKASSVSTKESPARKAAPAP-GKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEE 281
Query: 422 EAPA----QAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRS 477
EAPA Q K S K QVRAASAPAK +P KGA PAPP K G A+Q + GK EEDS S
Sbjct: 282 EAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSES 341
Query: 478 SSEES-DSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSA 536
SSEES DS+ E AA Q K GK+ QV AS KGA P PPGK GPA A
Sbjct: 342 SSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKA 401
Query: 537 QVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAK---------G 587
Q GK EEDS+SSSEES + APAQ K G Q + S+PAK
Sbjct: 402 QAGKREEDSQSSSEESDSEEE-------APAQAKPSGKAPQVRAASAPAKESPRKGAAPA 454
Query: 588 PPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKK 647
PP+K GP A QV+ K ++S SS E SDS EA AAM AAQ KP K PQ K
Sbjct: 455 PPRKTGPAAAQVQVGKQEEDSRSSSEESDS--DREALAAMNAAQVKPLGKSPQVKPASTM 512
Query: 648 TNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTG 707
PV P K G AT P+ G +SSS E SDS + +
Sbjct: 513 GMGPLGKGAGPV-----PPGKVGPAT------PSAQVGKWEEDSESSSEESSDSSDGEVP 561
Query: 708 LAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQED-SESSE 766
AV Q KS+G LQ K S P KG P K GP QVKAEK D SESSE
Sbjct: 562 TAVAPAQEKSLGNILQAKPTSSPAKGP---------PQKAGPVAVQVKAEKPMDNSESSE 612
Query: 767 EESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSK 826
E SDS ++ +PA + + K K A T SA V QA +++ +
Sbjct: 613 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTA 672
Query: 827 VKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEE----AE 882
P +P AVA Q P EDS SSEE SDSEEE A
Sbjct: 673 TSPAGSSP------------------AVAGGTQR---PAEDSSSSEE-SDSEEEKTGLAV 710
Query: 883 TLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQ--AGKQDDSGSSSEESD 940
T+ Q K GK Q++AA P K S +G AP PGKTGP+ Q A KQ+DS SS EESD
Sbjct: 711 TVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESD 770
Query: 941 SDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSE 1000
S+ AA + AQV V ++ A PAA A+A +A A TA + + +
Sbjct: 771 SE---EAAASPAQVKTS----VKKTQAKANPAA--ARAPSAKGTISAPGKVVTAAAQAKQ 821
Query: 1001 SEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPAT 1060
V P + P T + P + P + + A + + +++
Sbjct: 822 RSPSKVKPPVR--NPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEE 879
Query: 1061 QVDSAVGTLPA-TSPQSTSVQAKGTNKLRKPKLPEVQQAT-KAPESSDDSEDSSDSSSGS 1118
+ ++ P+ + Q + A RK P T + + +DS SS S
Sbjct: 880 EAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEES 939
Query: 1119 EEDGEGPQGAKSA 1131
+ DGE P SA
Sbjct: 940 DSDGEAPAAVTSA 952
Score = 265 bits (676), Expect = 3e-70
Identities = 294/977 (30%), Positives = 391/977 (40%), Gaps = 160/977 (16%)
Query: 457 RKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGP 516
RK AA + D S+SE S+ + EA A A + + V A
Sbjct: 63 RKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMK 122
Query: 517 LGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNIL 576
A GK G + P GK + S + T V+ +E+
Sbjct: 123 EKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG----- 177
Query: 577 QAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL 636
S PA G K G V A + +SE + SSD D E KP++
Sbjct: 178 -----SVPAFGAAAKPG----MVSAGQADSSSEDTSSSSDETDVE----------GKPSV 218
Query: 637 KIPQTKACPKKTNTTASAKVAPV--RVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSS 694
K Q KA T + + K AP +VG P+ G A PA + ++P E+S
Sbjct: 219 KPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRA-------KKPEEESE 271
Query: 695 SSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQV 754
SSEE SE E+ A T Q K+ K LQV+AAS P KG+ G+G P PGK G +Q
Sbjct: 272 SSEEG-SESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQT 330
Query: 755 KAEK-QEDSESSEEES-DSEE---AAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP 809
KA K +EDSESS EES DSEE AA + Q K S K +Q A A A+ KG AP
Sbjct: 331 KAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP 390
Query: 810 GKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGP-EEDS 868
P K P V A+AQ G EEDS
Sbjct: 391 --------------PGKTGPAV--------------------------AKAQAGKREEDS 410
Query: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAA--QA 926
SS EESDSEEEA AQ KPSGK Q+RAA APAKESPRKGAAP PP KTGP+AA Q
Sbjct: 411 QSSSEESDSEEEAP--AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQV 468
Query: 927 GKQ-DDSGSSSEESDSDGEAPAAVTSAQV--------IKP-PLIFVDPNRSPAGPAATPA 976
GKQ +DS SSSEESDSD EA AA+ +AQV +KP + + P AGP P
Sbjct: 469 GKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGP-VPPG 527
Query: 977 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAP--- 1033
+ A+ + E + SSS ES D + P ++ + A P +P
Sbjct: 528 KVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKG 587
Query: 1034 --------------KASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSV 1079
+ M + SS+ESS +D +E PA +A PA T
Sbjct: 588 PPQKAGPVAVQVKAEKPMDNSESSEESSDSAD--SEEAPAAM--TAAQAKPALKIPQTKA 643
Query: 1080 QAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSS-------------SGSEEDGEGPQ 1126
K TN K+ V+ T+AP + + + SS S S E+ + +
Sbjct: 644 CPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEE 703
Query: 1127 GAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATP 1186
VG S + L + A+ + + + +L G P +T +A K
Sbjct: 704 EKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQV--KAEKQED 761
Query: 1187 KLDSSPSVSSTLAAKDDPDGKQEAKPQQA----AGMLSPKTGGKEAASG-----TTPQKS 1237
S S AA K K QA A +P G +A G K
Sbjct: 762 SESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQ 821
Query: 1238 RKPKK---GAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVV 1294
R P K NPQ ST+ + + SV K + + +
Sbjct: 822 RSPSKVKPPVRNPQNSTVLARGPAS---------------VPSVGKAVATAAQAQTGPEE 866
Query: 1295 DTTKESSRKGWESRKRKLSGDQPAARTP--RSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1352
D+ E L+ +P+ +T R+ + G A P KT ++
Sbjct: 867 DSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQA 926
Query: 1353 AKRDKASGDVKEKKGKG 1369
K+D + +E G
Sbjct: 927 GKQDDSGSSSEESDSDG 943
Score = 234 bits (597), Expect = 5e-61
Identities = 224/643 (34%), Positives = 278/643 (43%), Gaps = 162/643 (25%)
Query: 72 QAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEK 131
+A K S+ ESS+ EEE A A + + S V A P+ + A
Sbjct: 331 KAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP 390
Query: 132 AGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMV 191
GKTG PA K A S S E + ++ + G P AA+ P
Sbjct: 391 PGKTG-----PAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKE 445
Query: 192 SAG------------------QADSSSEDTSSSSDETD-----------VEGKPSVKPAQ 222
S Q ED+ SSS+E+D + KP K Q
Sbjct: 446 SPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQ 505
Query: 223 VKASSVSTKESPARKAAPAP-GKVGDVTPQVKGG-----------------------ALP 258
VK +S + A P P GKVG TP + G A+
Sbjct: 506 VKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVA 565
Query: 259 PAK-------------------------------RAKKPEEESESSEEGSES--EEEAPA 285
PA+ +A+KP + SESSEE S+S EEAPA
Sbjct: 566 PAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPA 625
Query: 286 G-TRSQVKASEKILQVRAA------SAPAKGTPGK---------GATPAPPGKAGAVASQ 329
T +Q K + KI Q +A +A AK P + G +P G + AVA
Sbjct: 626 AMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGG 685
Query: 330 TKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPA 389
T+ +P EDS SSSEES EE+T A + QAK+ GK QV AAS P K S +G AP
Sbjct: 686 TQ--RPAEDS-SSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPV 742
Query: 390 PPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA--PAQAKPSGKAPQVRAASAPAKESP 447
PGKTGP V + +A K +EDS+SS EESDSEE A PAQ K S K Q +A A A+
Sbjct: 743 LPGKTGPTVTQVKAEK-QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPS 801
Query: 448 RKGAAPAP--------------PRKT---------------GPA-----------AAQVQ 467
KG AP P K GPA AAQ Q
Sbjct: 802 AKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQ 861
Query: 468 VGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPG 527
G EEDS SS EESDS+ EA AQVKP GK+ Q++ A KGA P PPG
Sbjct: 862 TGP-EEDSGSSEEESDSEEEA---ETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPG 917
Query: 528 KVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEK 570
K GP+ +AQ GK ++DS SSSEES SDGE P AV AQ++
Sbjct: 918 KTGPS--AAQAGK-QDDSGSSSEES--DSDGEAPAAVTSAQDQ 955
Score = 117 bits (294), Expect = 6e-26
Identities = 124/372 (33%), Positives = 165/372 (44%), Gaps = 89/372 (23%)
Query: 73 AKKTRVSDPISTSESSEEEEE-AEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEK 131
A + + P+ SESSEE + A++E A A A ++ +P + K T
Sbjct: 596 AVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL---KIPQTKACPKKTNTTA 652
Query: 132 AGKT-----GNSMPHPATGKTV----ANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAF 182
+ K G P A T + ++G + R + + S++ SE E+ G
Sbjct: 653 SAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTV 712
Query: 183 G------------AAAKPGMVSAGQADS-----------------SSEDTSSSSDETDVE 213
G AA+ P S GQ + ED+ SS +E+D E
Sbjct: 713 GQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSE 772
Query: 214 GKPSVKPAQVKASSVST--KESPARKAAP-------APGKVGDVTPQVK----------- 253
+ + PAQVK S T K +PA AP APGKV Q K
Sbjct: 773 -EAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPV 831
Query: 254 -------------------GGALPPAKRAKK-PEEESESSEEGSESEEEAPAGTRSQVKA 293
G A+ A +A+ PEE+S SSEE S+SEEEA T +QVK
Sbjct: 832 RNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAE--TLAQVKP 889
Query: 294 SEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEET 353
S K Q+RAA APAK +P KGA P PPGK G A+Q AGK ++DS SSSEE SDS+ E
Sbjct: 890 SGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQ--AGK-QDDSGSSSEE-SDSDGEA 945
Query: 354 PAAKALLQAKAS 365
PAA Q + S
Sbjct: 946 PAAVTSAQDQES 957
Score = 49.7 bits (117), Expect = 2e-05
Identities = 96/455 (21%), Positives = 164/455 (36%), Gaps = 53/455 (11%)
Query: 976 AQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKA 1035
A+ AA +K R S+ + S SSE E+E + TN + P +
Sbjct: 65 AEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLP-----S 119
Query: 1036 SMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPK---- 1091
SM + ++ G PAT + L SP+ ++ + T + + +
Sbjct: 120 SMKEKAKAETEKAGKTGNSMPHPATG-KTVANLLSGKSPRKSAEPSANTTLVSETEEEGS 178
Query: 1092 LPEVQQATKAPESSDDSEDSSD---SSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEE 1148
+P A K S DSS SSS E D EG K A ++ +
Sbjct: 179 VPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKA 238
Query: 1149 TAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQ 1208
A DV + G P +A K P+ +S S + + ++ P G +
Sbjct: 239 APAPGKVGDVTPQVKG--------GALPPAKRAKK--PEEESESSEEGSESEEEAPAGTR 288
Query: 1209 ----------EAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNI 1258
+ + A +P G A G + + K G + + + +S+
Sbjct: 289 SQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSD 348
Query: 1259 TQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPA 1318
++ + P +A +QA +++ KES RKG +G PA
Sbjct: 349 SE----EETPAAKALLQAKASGKTSQV-----GAASAPAKESPRKGAAPAPPGKTG--PA 397
Query: 1319 ARTPRSKKKKKLGAGEGGEASVSPEKTSTTSK--GKAKRDK-ASGDVKEKKGKGSLGSQG 1375
++ K+++ + E S S E+ +K GKA + + AS KE KG+ +
Sbjct: 398 VAKAQAGKREE-DSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPP 456
Query: 1376 AKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDK 1410
K P G + + +S E+ SD+
Sbjct: 457 RKTGP-----AAAQVQVGKQEEDSRSSSEESDSDR 486
Score = 41.6 bits (96), Expect = 0.006
Identities = 46/193 (23%), Positives = 81/193 (41%), Gaps = 24/193 (12%)
Query: 1271 EAQVQASVVKV-----LTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSK 1325
+A +QA +V +E E+E + +T K + R + L D P++ ++K
Sbjct: 68 DAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLA-STNSSVLGADLPSSMKEKAK 126
Query: 1326 KKKKLGAGEGGEASVSPEKTSTTSK---GKAKRDKASGD-----VKEKKGKGSLGSQGAK 1377
+ + AG+ G + P T + GK+ R A V E + +GS+ + GA
Sbjct: 127 AETEK-AGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA 185
Query: 1378 DEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQ 1437
+P G V G Q++ S+ SD+ + + K + K +S ESP++
Sbjct: 186 AKP--------GMVSAG-QADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPAR 236
Query: 1438 KKKKKKKKTAEQT 1450
K K + T
Sbjct: 237 KAAPAPGKVGDVT 249
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 162 bits (410), Expect = 2e-39
Identities = 315/1363 (23%), Positives = 473/1363 (34%), Gaps = 208/1363 (15%)
Query: 100 KATPRLASTNSSV-LGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPR 158
K +P ST+SS + +++ +K+ E GK +SM P + A+++ S
Sbjct: 568 KNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYA 627
Query: 159 --KSAEPSANTTLVSETEEEGSVPAFGA-AAKPGMVSAGQADSSSEDTSSSSDETDVEGK 215
SA P ++L++ T V AF +A P V+ A +S T+++S +EG
Sbjct: 628 GPDSAGPLLKSSLITPT-----VAAFPLESADPAGVAPTTAKGTSTYTTTASPF--LEGT 680
Query: 216 PSVKPAQ--VKASSVST-------------KESPARKAAPAPGKV--GDVTPQVKGGALP 258
S+ P VK +++T SP AP V ++ V +LP
Sbjct: 681 VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLP 740
Query: 259 PAKR---AKKPEEESESSEEG--SESEEEAPA--GTRSQVKASEKILQVRAASAPAKGTP 311
PA KK + S +S + S +E P S +S+ L A S G
Sbjct: 741 PAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVS 800
Query: 312 GKGATPAPPGKAGAVASQTKAGK------PEE-----DSESSSEESSDSEEET-----PA 355
T PP K G+ T G P E ++ S + S DS T P+
Sbjct: 801 VSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPS 860
Query: 356 AKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSE 415
K A S G + P KE+P P K GPA
Sbjct: 861 PKGAPTPSAVTPLSPKGV-TLPPKETPTPSVVNLPFPKEGPA------------------ 901
Query: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPA--KESPRKGAAPAPPRKTGPAAAQVQVGKQEE 473
+ + ++APA + S + RA AP SP AP PP T P
Sbjct: 902 -TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPP------------ 948
Query: 474 DSRSSSEESDSDREALAAMNAAQVKPLG----KSPQVKPASTMGMGPLGKGAGPVPPGKV 529
S + S + A A P G SP+ P P KG GP P
Sbjct: 949 -SPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG-GPATPSPK 1006
Query: 530 GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPP 589
G TP A + S +++ +S T +P + + + PT+ A P
Sbjct: 1007 GAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS 1066
Query: 590 QKAGPVAVQVK-AEKPMDNSESSEESSDSADSEEA---PAAMTAAQAKPALKIPQTKACP 645
K GP +K A P + S + + S + P A T K L P K P
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP 1126
Query: 646 KKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEK 705
TT +A + G P G T+PA + P+ GG P + + + +
Sbjct: 1127 ----TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182
Query: 706 TGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGT-----APVLPGKTGPTVTQVKAEKQE 760
G G A KG A+ P G T AP P T P + K
Sbjct: 1183 KG-----GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP------SPKGG 1231
Query: 761 DSESSEEESDSEEAAASPA-QVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQA 819
+ S + + + AA P+ + + + P AA PS KG ++ P
Sbjct: 1232 LATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP-------PHK 1284
Query: 820 KQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEE 879
+P+ V PP +P+ GPA+ P G AA P+ G+ +
Sbjct: 1285 GAPNPAVVTPP--SPKG------GPATSPPKGAPTPPAA-TPPSPKGSPGTPPPKGAPTP 1335
Query: 880 EAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEES 939
A T PS K A P+ KG TP K GP+ A G +
Sbjct: 1336 PAVT----PPSPKGTPTLPATTPSS----KGGPTTPSSKEGPT-PPAATPSHKGGPAMTP 1386
Query: 940 DSDGEAPAAVT-SAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSS 998
S PA + P +I + P ++P ATP + A+TP K + S
Sbjct: 1387 PSPKRGPAIPSPKGDPTSPAVIPLSPKKAP----ATPVTREGAATPSKGDLTPPAVTPVS 1442
Query: 999 SESEDEDVIPATQCLTPGIRTN----VVTMPTAHPRIAPKASMAGASSSKESSRISDGKK 1054
+ P TP + + VT P+ APK +A +SS K++
Sbjct: 1443 LKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPK-QVATSSSPKKA-------- 1493
Query: 1055 QEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDS 1114
PAT TLPA P S + R P P +K ++
Sbjct: 1494 ---PATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPAT--------- 1541
Query: 1115 SSGSEEDGEGPQGAKSAHTLVGPTPSRTETL--VEETAAESSEDDVVAPSQSLLSGYMTP 1172
P+ A + P+P +T + +E A S + +P P
Sbjct: 1542 --------LAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSP----------P 1583
Query: 1173 GLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGT 1232
+TP+ + + + +L P+V+S + K+ P P G +P G +
Sbjct: 1584 AVTPSTYKGAPSPKELLIPPAVTSP-SPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPV 1642
Query: 1233 TPQKSRKPKKGAGNPQASTLALQSNITQCLLGQP---WPLNEAQVQASVVKVLTELLEQE 1289
TP K +P + T + + + Q G P P +V + T ++
Sbjct: 1643 TPSSL---KDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAP 1699
Query: 1290 RKKVVDTTKESSR--------KGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVS 1341
+K T K S+ K LS PA P K K +G +AS S
Sbjct: 1700 TRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK--TAKGKDASHS 1757
Query: 1342 PEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEEL 1384
P+ + KA + ++ K S A P L
Sbjct: 1758 PKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSL 1800
Score = 89.7 bits (221), Expect = 2e-17
Identities = 163/707 (23%), Positives = 261/707 (36%), Gaps = 96/707 (13%)
Query: 216 PSVKPAQVKASSVSTKESPA----RKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESE 271
P P +S K++PA R+ A P K GD+TP A+ P K P +
Sbjct: 1398 PKGDPTSPAVIPLSPKKAPATPVTREGAATPSK-GDLTPP----AVTPVSLKKAPATSAP 1452
Query: 272 S---SEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVAS 328
+ S+ + PA T K QV +S+P K ATPAP G A
Sbjct: 1453 KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAP----ATPAPMG-----AP 1503
Query: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAP 388
A P E + SS + P A L S KT PA +P++ A
Sbjct: 1504 TLPAVIPSSPKEVPATPSSRRDPIAPTATLL-----SKKT--------PATLAPKE--AL 1548
Query: 389 APPGKTGPAVAKAQA--GKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKES 446
PP T P+ K A +E + SS+E+ S +P+ PA S
Sbjct: 1549 IPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK-ELLIPPAVTS 1607
Query: 447 PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 506
P AP PP T P+ + + + +S + S L SP
Sbjct: 1608 PSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSS--------------LKDSPTS 1653
Query: 507 KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 566
+ T MG A P K GP +E + + ES+ PT P
Sbjct: 1654 PASVTCKMGATVPQASKGLPAKKGPTA-------LKEVLVAPAPESTPIITA--PTRKGP 1704
Query: 567 AQEKSLGNILQAKPTSSP---AKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEA 623
+KS P S +KGP P + + +K + +++S S A
Sbjct: 1705 QTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPL-LPVQKDSSKTAKGKDASHSPKGPLA 1763
Query: 624 P------AAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPA- 676
P +TAA + L P++ + + S +AP V T P++ +SP
Sbjct: 1764 PPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGL 1823
Query: 677 ---GSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPV-K 732
S +A + E + V + KS G + +A PV K
Sbjct: 1824 VLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTK 1883
Query: 733 GSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKA 792
+ G GT ++ + + E+Q+ ++++ ++ ++ AAA+ + K Q+++
Sbjct: 1884 NNKGSGT------ESDSDESVPELEEQDSTQATTQQ--AQLAAAAEIDEEPVSKAKQSRS 1935
Query: 793 NPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPV-RNPQNSTVLARGPASVPSVG 851
A +A S G G ++K KP V ++P + T + G A + +
Sbjct: 1936 EKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLS 1995
Query: 852 KAVATAAQAQTGPEEDSGSS----------EEESDSEEEAETLAQVK 888
+ AA + + ++ S+ +EES+ EE ET +VK
Sbjct: 1996 QQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVK 2042
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 149 bits (375), Expect = 2e-35
Identities = 209/798 (26%), Positives = 297/798 (37%), Gaps = 169/798 (21%)
Query: 1 MAEARKRR----ELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQT 56
MA+A RR +L PL+ L A + + +G A +LLDIY+ W ++
Sbjct: 1 MADAGIRRVVPSDLYPLVLGFLRDNQLSEVANKFAKATGATQQDANASSLLDIYSFWLKS 60
Query: 57 SEL-GRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGA 115
+++ RK +A A +AKK S + +SSEEEEE + AK
Sbjct: 61 AKVPERKLQANGPVAKKAKKKASSS--DSEDSSEEEEEVQGPPAK--------------- 103
Query: 116 DLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEE 175
KA ++ G +P GK A S +S++ + +
Sbjct: 104 --------KAAVPAKRVG-----LP---PGKAAAKASESSSSEESSDDDDEEDQKKQPVQ 147
Query: 176 EGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPA 235
+G P AA P A +DS S+ SSS DE KP + P VKA +
Sbjct: 148 KGVKPQAKAAKAPPK-KAKSSDSDSD--SSSEDEPPKNQKPKITPVTVKAQT-------- 196
Query: 236 RKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASE 295
KA P P + P++ G +A S SS +SEEE
Sbjct: 197 -KAPPKPAR---AAPKIANG------KAASSSSSSSSSSSSDDSEEE------------- 233
Query: 296 KILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPA 355
+AA+ P K P K P KA A P S SS + SSD EEE
Sbjct: 234 -----KAAATPKKTVPKKQVVAKAPVKA--------ATTPTRKSSSSEDSSSDEEEE--- 277
Query: 356 AKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSE 415
K ++ K G S V SAP P+K PP K AV K Q + EDS S+
Sbjct: 278 QKKPMKNK-PGPYSSVPPPSAP---PPKKSLGTQPPKK---AVEKQQPVESSEDSSDESD 330
Query: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDS 475
S EE+ P P K K PP K+ +S
Sbjct: 331 SSSEEEKKP-----------------PTKAVVSKATTKPPP------------AKKAAES 361
Query: 476 RSSSEESDSDREALAAMNAAQVKPLG--KSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT 533
S S +SDS + + A KP G K+ KPA T + A P P G
Sbjct: 362 SSDSSDSDSSED-----DEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKL 416
Query: 534 PSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAG 593
+ + DS SS EESS S + + VA + K+ S PAK PQ +
Sbjct: 417 LTRKA-----DSSSSEEESSSSEEEKTKKMVATTKPKATAK----AALSLPAKQAPQGS- 466
Query: 594 PVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL----KIPQTKACPKKTN 649
SS+ S S++ EE + +A + KP P A KK
Sbjct: 467 -------------RDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGK 513
Query: 650 TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEES-DSEEEKTGL 708
+S + + K SP +P G + A++ +++ S + EEEK
Sbjct: 514 AESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKA 573
Query: 709 AVTVGQAKSVGKGLQ---VKAASVPVKGSLGQGTAPVLPGK-------TGPTVTQVKAEK 758
AV V ++ S+ K Q K A P + T P + + P + E
Sbjct: 574 AVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSPFRRVREEEI 633
Query: 759 QEDSESSEEESDSEEAAA 776
+ DS ++ D++ AA
Sbjct: 634 EVDSRVADNSFDAKRGAA 651
Score = 138 bits (348), Expect = 3e-32
Identities = 169/658 (25%), Positives = 246/658 (37%), Gaps = 137/658 (20%)
Query: 169 LVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQV----- 223
L S E + A G AK A SSS+ SS +E +V+G P+ K A
Sbjct: 58 LKSAKVPERKLQANGPVAKKAKKKA----SSSDSEDSSEEEEEVQGPPAKKAAVPAKRVG 113
Query: 224 ----KASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSES 279
KA++ +++ S + +++ + V+ G P AK AK P ++++SS+ S+S
Sbjct: 114 LPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDS 173
Query: 280 --EEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEE 337
E+E P + ++ Q +A PA+ P GKA + +S
Sbjct: 174 SSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAP-----KIANGKAASSSS--------- 219
Query: 338 DSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPA 397
S SSS S DSEEE AA+ P K P+K P K
Sbjct: 220 -SSSSSSSSDDSEEEK-------------------AAATPKKTVPKKQVVAKAPVKAATT 259
Query: 398 VAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPR 457
+ SSSE+S S+EE + K + P+ P+K PP+
Sbjct: 260 PTR---------KSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPK 310
Query: 458 KTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPL 517
K V+ + E S SS+ESDS E K P K
Sbjct: 311 KA------VEKQQPVESSEDSSDESDSSSEE------------EKKPPTKAV-------- 344
Query: 518 GKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGN--I 575
V AT K +S S S +S S D E P+ A + S +
Sbjct: 345 -----------VSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAV 393
Query: 576 LQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSE--------EAPAAM 627
P PA P Q G Q + D+S S EESS S + + + A
Sbjct: 394 TTKSPAVKPAAAPKQPVG--GGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATA 451
Query: 628 TAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRK--AGTATSPAGSSPAVAGG 685
AA + PA + PQ + ++S++ + A +K A A S PA A
Sbjct: 452 KAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKK 511
Query: 686 TQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPG 745
+ + +SSSS++S EEE+ K GKG + AP G
Sbjct: 512 GKAESSNSSSSDDSSEEEEE----------KLKGKGSP-------------RPQAPKANG 548
Query: 746 KTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAK 803
+ T KA K +SEEE + ++ AA S+KK + A P AK
Sbjct: 549 TSALTAQNGKAAK-----NSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAK 601
Score = 138 bits (347), Expect = 4e-32
Identities = 182/661 (27%), Positives = 251/661 (37%), Gaps = 171/661 (25%)
Query: 258 PPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATP 317
P AK+AKK S+S E+ SE EEE + A+ PAK
Sbjct: 73 PVAKKAKKKASSSDS-EDSSEEEEEVQGPP------------AKKAAVPAK------RVG 113
Query: 318 APPGKAGAVASQTKAGKPEEDSESSSEESSDSEEET------------PAAKALLQAKAS 365
PPGKA A AS++ SSSEESSD ++E P AKA
Sbjct: 114 LPPGKAAAKASES----------SSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKK 163
Query: 366 GKTSQVGAASAPAKESPR-------------KGAAPAPPGKTGPAVAKAQAGKREEDSQS 412
K+S + S+ E P+ + AP P + P +A +A S S
Sbjct: 164 AKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSS 223
Query: 413 SSEESDSEEEAPAQAKPSGKAPQVRA-ASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQ 471
SS DSEEE A A P P+ + A AP K AA P RK+
Sbjct: 224 SSSSDDSEEEKAA-ATPKKTVPKKQVVAKAPVK------AATTPTRKS------------ 264
Query: 472 EEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGP-VPPGKVG 530
SSSE+S SD E Q KP+ P GP P PP K
Sbjct: 265 -----SSSEDSSSDEEE------EQKKPMKNKP----------GPYSSVPPPSAPPPKKS 303
Query: 531 PATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQ 590
T + ++ SSE+SSD SD +S K PP
Sbjct: 304 LGTQPPKKAVEKQQPVESSEDSSDESDS----------------------SSEEEKKPPT 341
Query: 591 KAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNT 650
KA V KP +++E SSDS+DS+ + A +KPA T
Sbjct: 342 KA---VVSKATTKPPPAKKAAESSSDSSDSDSSED--DEAPSKPA-------------GT 383
Query: 651 TASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQ----RPAEDSSSSEESDS-EEEK 705
T ++ P V T++P A PA + GG Q R A+ SSS EES S EEEK
Sbjct: 384 TKNSSNKPA-VTTKSP-----AVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEK 437
Query: 706 TGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESS 765
T V + K+ K A LP K P Q + DS+SS
Sbjct: 438 TKKMVATTKPKATAKA------------------ALSLPAKQAP---QGSRDSSSDSDSS 476
Query: 766 EEESDSEEAAASPAQVKTS-VKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSP 824
E + E+ + S + K V A + PA+A+ A+ + S+ + + K +
Sbjct: 477 SSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGK 536
Query: 825 SKVKP--PVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAE 882
+P P N ++ G A+ S + A + S +++++ +EAE
Sbjct: 537 GSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAE 596
Query: 883 T 883
T
Sbjct: 597 T 597
Score = 128 bits (322), Expect = 3e-29
Identities = 193/776 (24%), Positives = 271/776 (34%), Gaps = 167/776 (21%)
Query: 585 AKGPPQKA---GPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQT 641
AK P +K GPVA K K +S SE+SS+ + + P A AA + +P
Sbjct: 61 AKVPERKLQANGPVA---KKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPG 117
Query: 642 KACPKKTNTTASA-----------KVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPA 690
KA K + +++S K PV+ G + KA A + A
Sbjct: 118 KAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPP-------------KKA 164
Query: 691 EDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPT 750
+ S S +S SE+E K + K V VK Q AP P + P
Sbjct: 165 KSSDSDSDSSSEDEPP-------------KNQKPKITPVTVKA---QTKAPPKPARAAPK 208
Query: 751 VTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQ--AKANPAAARAPSAKGTISA 808
+ KA S SS SD E + A K +V K Q AKA AA P+ K + S
Sbjct: 209 IANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSE 268
Query: 809 PGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS 868
++ + +Q+ P K KP P +S P S+G A + P E S
Sbjct: 269 DS---SSDEEEEQKKPMKNKP---GPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESS 322
Query: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGK 928
S +ESDS E E KP P K K PP K A
Sbjct: 323 EDSSDESDSSSEEEK----KP------------PTKAVVSKATTKPPPAKK----AAESS 362
Query: 929 QDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKAR 988
D S S S E D PA T KP + P PA P RKA
Sbjct: 363 SDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKAD 422
Query: 989 ASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGA-SSSKESS 1047
+S S SSSSE E + AT T P A + A A S++SS
Sbjct: 423 SSSSEEESSSSEEEKTKKMVAT------------TKPKATAKAALSLPAKQAPQGSRDSS 470
Query: 1048 RISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDD 1107
SD E + S S K K+ P + K ++
Sbjct: 471 SDSDSSSSEEEEEKT-------------SKSAVKKKPQKVAGGAAPSKPASAKKGKAESS 517
Query: 1108 SEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLS 1167
+ SSD SS EE+ +G+ P P AP +
Sbjct: 518 NSSSSDDSSEEEEEKLKGKGS--------PRPQ-------------------APKAN--- 547
Query: 1168 GYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKE 1227
T LT N +A+K + ++E + ++ A ++ K+G +
Sbjct: 548 --GTSALTAQNGKAAK---------------------NSEEEEEEKKKAAVVVSKSGSLK 584
Query: 1228 AASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLE 1287
+K + K A PQA + LQ+ T E + + +V E +E
Sbjct: 585 ------KRKQNEAAKEAETPQAKKIKLQTPNT----FPKRKKGEKRASSPFRRVREEEIE 634
Query: 1288 QERKKVVDTTKESSRKG---WESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASV 1340
+ +V D + ++ R W R ++ K KKK G+ GG SV
Sbjct: 635 VD-SRVADNSFDAKRGAAGDWGERANQVLKFTKGKSFRHEKTKKKRGSYRGGSISV 689
Score = 112 bits (280), Expect = 3e-24
Identities = 168/663 (25%), Positives = 254/663 (38%), Gaps = 138/663 (20%)
Query: 796 AARAPSAKGTISAP--GKVVTAAAQAKQRSPSKVKPPVRNP--QNSTVLARGPASVPSVG 851
+A+ P K + P K A+ + S+ + V+ P + + V A+ P G
Sbjct: 60 SAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPP--G 117
Query: 852 KAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGA 911
KA A A++ S SSEE SD ++E + Q G Q +AA AP K++
Sbjct: 118 KAAAKASE--------SSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAK---- 165
Query: 912 APTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPA---AVTSAQVIKPPLIFVDPNRSP 968
DS SSSE+ + P AQ PP P
Sbjct: 166 ---------------SSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPP--------KP 202
Query: 969 AGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAH 1028
A A A +AAS+ S S++ SSSS+ +E+ AT T + V P
Sbjct: 203 ARAAPKIANGKAASS------SSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAP--- 253
Query: 1029 PRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLR 1088
+ + SSS E S + ++Q+ P ++P P S K
Sbjct: 254 --VKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVP---PPSAPPPKKSLGTQP 308
Query: 1089 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSR--TETLV 1146
K E QQ ESS+DS D SDSSS EE+ + P A + P P++ E+
Sbjct: 309 PKKAVEKQQPV---ESSEDSSDESDSSS--EEEKKPPTKAVVSKATTKPPPAKKAAESSS 363
Query: 1147 EETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDG 1206
+ + ++SSEDD APS+ G T +S T K SP+V A K G
Sbjct: 364 DSSDSDSSEDDE-APSKPA-------GTTKNSSNKPAVTTK---SPAVKPAAAPKQPVGG 412
Query: 1207 KQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQP 1266
Q+ ++A + E S ++ ++ K P+A+ A
Sbjct: 413 GQKLLTRKA------DSSSSEEESSSSEEEKTKKMVATTKPKATAKAA------------ 454
Query: 1267 WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKK 1326
L K+ +++SS S S ++ +T +S
Sbjct: 455 -------------------LSLPAKQAPQGSRDSSSDSDSS-----SSEEEEEKTSKSAV 490
Query: 1327 KKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQK 1386
KKK GG A P K ++ KGKA+ +S S E EEE K
Sbjct: 491 KKKPQKVAGGAA---PSKPASAKKGKAESSNSS-------------SSDDSSEEEEEKLK 534
Query: 1387 GMGTVEG-GDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1445
G G+ ++N S + K +E++E+K KKA+ S+S S KK+K+ +
Sbjct: 535 GKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEK---KKAAVVVSKSGSLKKRKQNEA 591
Query: 1446 TAE 1448
E
Sbjct: 592 AKE 594
Score = 105 bits (263), Expect = 2e-22
Identities = 145/609 (23%), Positives = 234/609 (38%), Gaps = 129/609 (21%)
Query: 900 LAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPL 959
L AK RK A P K A + +DS EE AAV + +V PP
Sbjct: 58 LKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPG 117
Query: 960 IFV-------------------DPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSE 1000
D + P P A + P+KA++S+S + SSS +
Sbjct: 118 KAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSED 177
Query: 1001 SEDEDVIPATQCLTPGIRTNVVTMPT-AHPRIAPKASMAGASSSKESSRISDGKKQEGPA 1059
++ P +T +T P A P+IA + + +SSS SS D ++++ A
Sbjct: 178 EPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAA 237
Query: 1060 T--------QVDSAVGTLPATSPQSTSVQAKGTN-----KLRKPKL-------------- 1092
T QV + AT+P S ++ ++ + +KP
Sbjct: 238 TPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSA 297
Query: 1093 --PEVQQATKAP----------ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPS 1140
P+ T+ P ESS+DS D SDSS SEE+ + P A + P P+
Sbjct: 298 PPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSS--SEEEKKPPTKAVVSKATTKPPPA 355
Query: 1141 R--TETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTL 1198
+ E+ + + ++SSEDD APS+ G T +S T K SP+V
Sbjct: 356 KKAAESSSDSSDSDSSEDD-EAPSK-------PAGTTKNSSNKPAVTTK---SPAVKPAA 404
Query: 1199 AAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNI 1258
A K G Q+ ++A + E S ++ ++ K P+A+ A
Sbjct: 405 APKQPVGGGQKLLTRKA------DSSSSEEESSSSEEEKTKKMVATTKPKATAKA----- 453
Query: 1259 TQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPA 1318
L+ +Q + D++ +S E + K S
Sbjct: 454 ----------------------ALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTS----- 486
Query: 1319 ARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEK-KGKGSLGSQGAK 1377
++ KK +K+ G S +K S + D +S + +EK KGKGS
Sbjct: 487 -KSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGS------- 538
Query: 1378 DEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKK-----DKEKKEKKKKAKKASTKDS 1432
P + K GT Q+ +K +++ +++KK K KK+K +A+ K++
Sbjct: 539 --PRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAA-KEA 595
Query: 1433 ESPSQKKKK 1441
E+P KK K
Sbjct: 596 ETPQAKKIK 604
Score = 63.9 bits (154), Expect = 1e-09
Identities = 73/300 (24%), Positives = 121/300 (40%), Gaps = 50/300 (16%)
Query: 73 AKKTRVSDPISTSESSEEEEEAEAETAKAT------PRLASTNSSVLGADLP-------- 118
AKK S S+ S E++EA ++ A T P + + + +V A P
Sbjct: 355 AKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQ 414
Query: 119 ----------SSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTT 168
SS +E + +E EK K + AT K +L + ++P+ S + S+++
Sbjct: 415 KLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSD 474
Query: 169 LVSETEEE-----------------GSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETD 211
S EEE G+ P+ A+AK G A ++SSS D SS +E
Sbjct: 475 SSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKG--KAESSNSSSSDDSSEEEEEK 532
Query: 212 VEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQV-----KGGALPPAKR--AK 264
++GK S +P KA+ S + KAA + + + K G+L K+ A
Sbjct: 533 LKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAA 592
Query: 265 KPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAG 324
K E ++ + ++ P + + +AS +VR + A G AG
Sbjct: 593 KEAETPQAKKIKLQTPNTFPKRKKGEKRASSPFRRVREEEIEVDSRVADNSFDAKRGAAG 652
Score = 54.3 bits (129), Expect = 8e-07
Identities = 82/377 (21%), Positives = 143/377 (37%), Gaps = 81/377 (21%)
Query: 1087 LRKPKLPE--------VQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTL--VG 1136
L+ K+PE V + K SS DSEDSS+ EE+ +GP K+A VG
Sbjct: 58 LKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEE----EEEVQGPPAKKAAVPAKRVG 113
Query: 1137 PTPSRTETLVEETAA--ESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSV 1194
P + E+++ ESS+DD + + G+ P ++A+KA PK S
Sbjct: 114 LPPGKAAAKASESSSSEESSDDD---DEEDQKKQPVQKGVKP-QAKAAKAPPKKAKSSDS 169
Query: 1195 SSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLAL 1254
S +++D+P Q+ K ++P T +A + P+ +R K A AS+
Sbjct: 170 DSDSSSEDEPPKNQKPK-------ITPVT--VKAQTKAPPKPARAAPKIANGKAASS--- 217
Query: 1255 QSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSG 1314
++ SS +S + K
Sbjct: 218 ----------------------------------------SSSSSSSSSSDDSEEEK--- 234
Query: 1315 DQPAARTPRSK-KKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS 1373
AA TP+ KK++ A +A+ +P + S++S+ + ++ K G S
Sbjct: 235 ---AAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSS 291
Query: 1374 QGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSE 1433
P + K +GT + E + + D +E+KK KA +
Sbjct: 292 VPPPSAPPPK--KSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKAT 349
Query: 1434 SPSQKKKKKKKKTAEQT 1450
+ KK + +++ +
Sbjct: 350 TKPPPAKKAAESSSDSS 366
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 124 bits (310), Expect = 9e-28
Identities = 299/1580 (18%), Positives = 550/1580 (34%), Gaps = 256/1580 (16%)
Query: 72 QAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEK 131
Q KK + D SESS E + + K R S + S + K K K++ +K
Sbjct: 187 QKKKKKKKDRGRRSESSSPRRERKKSSKKKKHR--SESESKKRKHRSPTPKSKRKSKDKK 244
Query: 132 AGKTGNSMPHP--------ATGKTVANLLSGKSPRKSAEPSANTTLV--------SETEE 175
++ ++ P P + + ++ + +S +SA +TT + S
Sbjct: 245 RKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRG 304
Query: 176 EGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSD-----ETDVEGKPSVKPAQVKASSVST 230
EG P ++PG S + S T S + D + K + +P+ S +
Sbjct: 305 EGDAP----FSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTG 360
Query: 231 KESPARKAAPAPGKVGD-----VTPQVKGGALPPAK----RAKKPEEESESSEEGSESEE 281
E PA A G TP + PP++ R + P + E + S SE
Sbjct: 361 PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSES 420
Query: 282 EAPAGTRSQVKASEKILQVRAASAPAKGTPGK-GATPAPPGKAGAVA------SQTKAGK 334
P+ ++V APA G+ + ++P ++ A S T + +
Sbjct: 421 SPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRR 480
Query: 335 PEEDSESSSEESSDSEEETPAAKALLQAKA-----SGKTSQVGAASAPAKESPRKGAAPA 389
++ + S TP + ++++ S + G + +P + + +P
Sbjct: 481 MGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRG--RSRSPQ 538
Query: 390 PPG----------------KTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKA 433
PG + G + +++ A + S++ + S PA+ + +
Sbjct: 539 RPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRT 598
Query: 434 PQVRAASA--PAKESPRKGAAPA------------------PPRKTGPAAAQVQVGKQEE 473
P R + + PA+ + PA P R++G + ++ +
Sbjct: 599 PTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRS 658
Query: 474 DSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT 533
SR+ + S R A + + + + + + S + V G+ T
Sbjct: 659 RSRTPARRGRS-RSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRT 717
Query: 534 PSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSP-AKGPPQKA 592
P + S S + S +S + +P +KS + +++ SSP +K + +
Sbjct: 718 PQR---RGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLS 774
Query: 593 GPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIP---QTKACPKKTN 649
++ + P S++ S S S+ + T + + P Q P + +
Sbjct: 775 LRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQS 834
Query: 650 TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLA 709
++S+ V+ GT P + G+ TSP + +V +R +SS E S
Sbjct: 835 HSSSSPHPKVKSGT--PPRQGSITSPQANEQSVT-PQRRSCFESSPDPELKSR------- 884
Query: 710 VTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP-------VLP------GKTGPTVTQVKA 756
T + G +S P + S + ++P + P G + P+ ++V +
Sbjct: 885 -TPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTS 943
Query: 757 EKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAA 816
S + E+ P + K P S G+IS KV
Sbjct: 944 RTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQT 1003
Query: 817 AQAKQRSPSKVKPPVRNPQNSTV--------LARGPASVPSVGK------AVATAAQAQT 862
S SK P ++S V L G S G+ ++ Q+QT
Sbjct: 1004 PPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQT 1063
Query: 863 GPEEDSG-SSEEESDSEEEAETL---AQVKP-SGKTHQIRAALAPAKESP----RKGAAP 913
P+ S SS E S E+ +L +Q P G++ A SP R +
Sbjct: 1064 SPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSA 1123
Query: 914 TPPGKTGPSAAQAGKQDDSGS----SSEESDSDGEAPAAVTSAQVIKPP----------- 958
+P K+G S Q+ Q DS S S A + ++ PP
Sbjct: 1124 SPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQ 1183
Query: 959 ----------------LIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESE 1002
L+F D R+P P + A + + + S +SS + E
Sbjct: 1184 KDKFSPFPVQDRPESSLVFKDTLRTP------PRERSGAGSSPETKEQNSALPTSSQDEE 1237
Query: 1003 DEDVI-----PATQCLTPGIRTNVVTMPTAHPRIAPK----------------------- 1034
+V+ PA Q L+ + + + M T++ +P+
Sbjct: 1238 LMEVVEKSEEPAGQILS-HLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAV 1296
Query: 1035 ------ASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLR 1088
+S G S E +S+ +E + P + +T ++ L
Sbjct: 1297 EVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLN 1356
Query: 1089 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGP-------TPSR 1141
P L +++ + S SSS D G S ++ P TPSR
Sbjct: 1357 GPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSR 1416
Query: 1142 TETLVEETAAESSEDDVVAPSQSLLSGYMTPGL-----TPANSQASKATPKLDSSPSVSS 1196
E ++ E + PS+ SG +PGL TP+ S ++P + P S
Sbjct: 1417 -ERSSSASSPEMKDGLPRTPSRRSRSG-SSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPS 1474
Query: 1197 TLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQS 1256
++ D + +A PQ +P+ + +S K P++ ++S Q
Sbjct: 1475 RGRSECDSSPEPKALPQ------TPRPRSRSPSSPELNNKCLTPQRERSGSESS--VDQK 1526
Query: 1257 NITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQ 1316
+ + LGQ + + V QER + + ++ R+R SG
Sbjct: 1527 TVARTPLGQ----RSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSS 1582
Query: 1317 P--------------AARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDV 1362
P + +P K K + + SPE + + +R + SG
Sbjct: 1583 PEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSR-SGSS 1641
Query: 1363 KEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKK 1422
+ +G GS + PE + T G +S+P+ K + + +R+ + E +
Sbjct: 1642 SKGRGPSPEGSSSTESSPEHPPKS--RTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTR 1699
Query: 1423 KAKKASTKDSESPSQKKKKK 1442
KA+ + S S S + + +
Sbjct: 1700 KARLSRRSRSASSSPETRSR 1719
Score = 104 bits (260), Expect = 5e-22
Identities = 242/1319 (18%), Positives = 459/1319 (34%), Gaps = 205/1319 (15%)
Query: 243 GKVGDVTPQVKG--GALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQV------KAS 294
G+ TPQ +G G+ K + + S E ++ + RS+ KA
Sbjct: 711 GRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAK 770
Query: 295 EKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETP 354
++ R+ S + K TP ++G+ + K+ P S SSS + +TP
Sbjct: 771 SRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP 830
Query: 355 AAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSS 414
S+ +S+ + G P T P + + SS
Sbjct: 831 --------------SRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESS 876
Query: 415 EESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAP-------PRK------TGP 461
+ + + P++ SG +P +S P ++SP + ++P P PR+ + P
Sbjct: 877 PDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSP 936
Query: 462 AAAQVQVGKQEEDSRSSSEESDSDREAL-------AAMNAAQVKP-----------LGKS 503
+ ++V SRS S S+ + L ++ +VKP +
Sbjct: 937 SPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPY 996
Query: 504 PQVKPASTMG-----------------------MGPLGKGAG---PVPPGKVGPATPSAQ 537
P+VK + G G L AG PPG+ S Q
Sbjct: 997 PKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQ 1056
Query: 538 VGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAV 597
+ + S++S + SD+S EV Q S LQ+K +SP G + + PV
Sbjct: 1057 L---KGQSQTSPDHRSDTSSPEV------RQSHSESPSLQSKSQTSPKGGRSRSSSPVTE 1107
Query: 598 ------------QVKAEKPMDNSESSEESSDSADSEEAP----------AAMTAAQAKPA 635
+ A + + S E+S +DS P + + A++K
Sbjct: 1108 LASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEK 1167
Query: 636 LKIP---QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAED 692
+ +P A P + S R + K T P S AG + E
Sbjct: 1168 MALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSG--AGSSPETKEQ 1225
Query: 693 SSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT 752
+S+ S +EE + V + G+ L ++ + + ++P + + ++T
Sbjct: 1226 NSALPTSSQDEEL--MEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLT 1283
Query: 753 QVKAEKQEDSESSEEESDSEEAAA---SP--AQVKTSVKKTQAKANPAAARAPSAKGTIS 807
+++ Q E+ E S + SP ++ S + + +P R GT
Sbjct: 1284 LDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEM 1343
Query: 808 APGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE-- 865
G S+VK + P + + + + + ++ P+
Sbjct: 1344 NTG------------FSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAV 1391
Query: 866 EDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQ 925
E +G S +S S + + + PS R + A K P P + S +
Sbjct: 1392 EKAGMSSNQSISSPVLDAVPRT-PS------RERSSSASSPEMKDGLPRTPSRRSRSGSS 1444
Query: 926 AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR 985
G +D SG+ S S S G +P + P+R + ++P TPR
Sbjct: 1445 PGLRDGSGTPSRHSLS-GSSPGMKDIPRT---------PSRGRSECDSSPEPKALPQTPR 1494
Query: 986 KARASEST------------ARSSSSESEDEDVI---PATQCLTPGIRTNVVTMPTAHPR 1030
S S+ RS S S D+ + P Q G + P+A P+
Sbjct: 1495 PRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQ 1554
Query: 1031 IAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKP 1090
++ + S +K + + + + G + +VDS P S +S + K + P
Sbjct: 1555 ERSESDSSPDSKAKTRTPLRQ-RSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPR-AAP 1612
Query: 1091 KLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETA 1150
+ ++ P++ S SGS G GP S+ T P +
Sbjct: 1613 RAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGS 1672
Query: 1151 AESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVS-STLAAKDDPDGKQE 1209
S E T TP ++S+++P+L +S + +A P+ +
Sbjct: 1673 RSSPEP-------------KTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSR 1719
Query: 1210 AKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPL 1269
P+ SP E A +S + ++ A +P+ T + + +P L
Sbjct: 1720 TPPRHRR---SPSVSSPEPAE---KSRSSRRRRSASSPRTKTTSRRGRSPS---PKPRGL 1770
Query: 1270 NEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESR--KRKLSGDQPAARTPRSKKK 1327
++ ++ K T T++ R SR +R+ G +R+P ++
Sbjct: 1771 QRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQES 1830
Query: 1328 KKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKG 1387
+ + S +T TS+ +++ + K + + S + + +
Sbjct: 1831 SRTSSRRRRGRS----RTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRR 1886
Query: 1388 MGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKT 1446
S +S+ + +R + + +++++ S +P +++ + +T
Sbjct: 1887 RSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSR------SRTPPVTRRRSRSRT 1939
Score = 103 bits (256), Expect = 2e-21
Identities = 255/1354 (18%), Positives = 451/1354 (33%), Gaps = 223/1354 (16%)
Query: 98 TAKATPRLASTNSSVLGADLPSSMKEKAKA--ETEKAGKTGNSMPHPATGKTVANLLSGK 155
+ + PR+ S+ SS + K KA + +G+S P P+ + S
Sbjct: 892 SGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPS------RVTSRT 945
Query: 156 SPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGK 215
+PR+S S + + S +P + + S S D + K
Sbjct: 946 TPRRSRSVSPCSNVESRL-----LPRY--------------------SHSGSSSPDTKVK 980
Query: 216 PSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESS-E 274
P P Q + S+S + P P G +P P+E+S+ S
Sbjct: 981 PETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSP--------------CPQEKSKDSLV 1026
Query: 275 EGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGK 334
+ AG +S E V +S KG SQT
Sbjct: 1027 QSCPGSLSLCAGVKSSTPPGESYFGV--SSLQLKG-----------------QSQT---S 1064
Query: 335 PEEDSESSSEESSDSEEETPAAKALLQ-------AKASGKTSQVGAASAPAKESPRKGAA 387
P+ S++SS E S E+P+ ++ Q +++S +++ + S ++ A+
Sbjct: 1065 PDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSAS 1124
Query: 388 PAPPGKTGPAVAKAQAGKREEDS--------QSSSEESDSEEE--APAQAKPSGKAPQVR 437
P P ++ Q+ + QS E ++S+E+ P Q + P+ +
Sbjct: 1125 PMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQK 1184
Query: 438 AASAPAKESPR-------KGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALA 490
+P R K PPR+ A + + +Q S+ S D E +
Sbjct: 1185 DKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQ----NSALPTSSQDEELME 1240
Query: 491 AMNAAQVKPLGK-----SPQVKPASTMGMGPLGK-GAGPVPPGKVGPATPSAQVGKWEED 544
+ ++ +P G+ S ++K ST + P + + A + E
Sbjct: 1241 VVEKSE-EPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVP 1299
Query: 545 SESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAK---------PTSSPAKGPPQKAGPV 595
S +SS S + +P +E S G+ L+ + T ++ GP
Sbjct: 1300 SMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPF 1359
Query: 596 AVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAA--QAKPALKIPQTKACPKKTNTTAS 653
Q++ + +D E S SS + SE +P A+ A + ++ P A P+ + S
Sbjct: 1360 LNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERS 1419
Query: 654 AKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVG 713
+ + + PR + S +GSSP + G+ P+ S S ++ +
Sbjct: 1420 SSASSPEMKDGLPR-TPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKD--------IP 1470
Query: 714 QAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEE 773
+ S G+ + S P +L Q P + P + Q + SE D +
Sbjct: 1471 RTPSRGRS---ECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKT 1527
Query: 774 AAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRN 833
A +P ++ +Q +A + S+P +QRS S P V +
Sbjct: 1528 VARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDS 1587
Query: 834 PQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKT 893
+ S P V A +AQ+G SDS E + A P
Sbjct: 1588 KSRLSPRRSRSGSSPEVKDKPRAAPRAQSG-----------SDSSPEPKAPA---PRALP 1633
Query: 894 HQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ 953
+ R+ S KG P+P GSSS ES + +
Sbjct: 1634 RRSRSG------SSSKGRGPSP----------------EGSSSTESSPEHPPKSRTARRG 1671
Query: 954 VIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCL 1013
P +P P + + RKAR S + +SSS P T+
Sbjct: 1672 SRSSP----EPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSS--------PETRSR 1719
Query: 1014 TPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATS 1073
T P H R +S A S+ S R + P T+ S G P+
Sbjct: 1720 T----------PPRHRRSPSVSSPEPAEKSRSSRR---RRSASSPRTKTTSRRGRSPSPK 1766
Query: 1074 PQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHT 1133
P +G + R E + T+ + S S+ +S S + +
Sbjct: 1767 P-------RGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSG 1819
Query: 1134 LVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPG--------LTPANSQASKA- 1184
+P+R E+ + S+ +P +PA + S++
Sbjct: 1820 YHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSR 1879
Query: 1185 TPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGA 1244
TP + S S T + + ++ + + + + S T P R+ +
Sbjct: 1880 TPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRT 1939
Query: 1245 GNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKG 1304
+ + + +T+ P + S +T + R V + SR
Sbjct: 1940 PTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTS 1999
Query: 1305 WESRKRKLSGDQPA------------------ARTPRSKKKKKLGAGEGGEASVSPEKTS 1346
+R+R S P +RTP +K+ S +T
Sbjct: 2000 PVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTP 2059
Query: 1347 TTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEP 1380
T++GK ++ ++ + GS + P
Sbjct: 2060 RTARGKRSLTRSPPAIRRRSASGSSSDRSRSATP 2093
Score = 99.4 bits (246), Expect = 2e-20
Identities = 261/1315 (19%), Positives = 477/1315 (36%), Gaps = 183/1315 (13%)
Query: 235 ARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKAS 294
A++ AP P K + + P K+ KK +++ + G SE +P R + K S
Sbjct: 160 AKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKK----DRGRRSESSSP---RRERKKS 212
Query: 295 EKILQVRAASAPAKGTPGKGATPAPPGKAGAV-------ASQTKAGKPEEDSESSSEESS 347
K + R+ S K K +P P K + S T A K S+S +S+
Sbjct: 213 SKKKKHRSESESKKR---KHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSA 269
Query: 348 DSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKRE 407
S + T +++ A + T+ G + +PA S R+G AP ++ G
Sbjct: 270 SSSD-TSRSRSRSAAAKTHTTALAGRSPSPA--SGRRGEGDAP---------FSEPGTTS 317
Query: 408 EDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQ 467
SS E + + +P + K K + ++A+ P+ R P PP T P A+
Sbjct: 318 TQRPSSPETATKQPSSPYEDKDKDK--KEKSATRPSPSPERSSTGPEPPAPT-PLLAERH 374
Query: 468 VGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP-P 526
G + + + + + + A+ + P KSP+ P S+ + + P P P
Sbjct: 375 GGSPQPLATTPLSQEPVNPPSEASPTRDRSPP--KSPEKLPQSSS-----SESSPPSPQP 427
Query: 527 GKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS-SPA 585
KV S+ + S E S S PT ++ +S G + K S +P+
Sbjct: 428 TKVSRHASSSPESPKPAPAPGSHREISSS-----PT----SKNRSHGRAKRDKSHSHTPS 478
Query: 586 KGPPQKAGPVAV---QVKAEKPMDNSESSEESSDSADSEEAP--AAMTAAQAKPALKIPQ 640
+ + P + ++ P S S S A + Q + + PQ
Sbjct: 479 RRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQ 538
Query: 641 TKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAG--GTQRPAEDSSSSEE 698
+ NT + R G R T +PA G ++ PA S S
Sbjct: 539 RPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRT 598
Query: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPV---------LPGKTGP 749
++ G+++S + PV+ + +P P + G
Sbjct: 599 PTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVR-RRSRSRSPARRSGRSRSRTPARRGR 657
Query: 750 TVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAA----------ARA 799
+ ++ A + + + +PA+ S +T + + +R
Sbjct: 658 SRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRT 717
Query: 800 PSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPS---------- 849
P +G + + + +++RS S P ++ + S+ +R +S S
Sbjct: 718 PQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRR 777
Query: 850 --VGKAVATAAQAQTGPEED-SGSSEEESDSE---EEAETLAQVKPSGKTHQIRAALAPA 903
G + ++QT P SGSS+ ++ S + + + P K+ +
Sbjct: 778 SLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSS 837
Query: 904 KESPRKGAAPTPPGKTGPSAAQAGKQ--------------------------DDSGSSS- 936
K + TPP + ++ QA +Q SGSS
Sbjct: 838 SSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPP 897
Query: 937 --EESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAA-TPAQAQAASTPRKARASEST 993
+ S ++P+ +S Q K I RS +G ++ +P++ + +TPR++R+
Sbjct: 898 RVKSSTPPRQSPSRSSSPQP-KVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPC 956
Query: 994 AR----------SSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSS 1043
+ S S S D V P T ++ P + P S++G+ S
Sbjct: 957 SNVESRLLPRYSHSGSSSPDTKVKPETP-PRQSHSGSISPYPKVKAQTPPGPSLSGSKSP 1015
Query: 1044 KESSRISDGKKQEGPATQVDSAVGTLPATSPQS-----TSVQAKGTNKLRKPKLPEVQQA 1098
+ D Q P + + G +T P +S+Q KG ++ P+ +
Sbjct: 1016 CPQEKSKDSLVQSCPGS-LSLCAGVKSSTPPGESYFGVSSLQLKGQSQTS----PDHRSD 1070
Query: 1099 TKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAES--SED 1156
T +PE +S S S+ P+G + SR+ + V E A+ S +D
Sbjct: 1071 TSSPEVRQSHSESPSLQSKSQ---TSPKGGR----------SRSSSPVTELASRSPIRQD 1117
Query: 1157 DVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAA 1216
+ +L M+P + S +S + P +DS+ + + + K PQ+ A
Sbjct: 1118 RGEFSASPMLKSGMSPEQSRFQSDSS-SYPTVDSNSLLGQSRLETAESKEKMALPPQEDA 1176
Query: 1217 GMLSPKTGGKEAASGT--TPQKS-------RKPKKGAGNPQASTLALQSNITQCLLGQPW 1267
P+ K + P+ S R P + +S + N Q
Sbjct: 1177 TASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDE 1236
Query: 1268 PLNEA--QVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSK 1325
L E + + ++L+ L E K++ + ESS + E L+ DQ ++
Sbjct: 1237 ELMEVVEKSEEPAGQILSH-LSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEA 1295
Query: 1326 KKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ---GAKDEPEE 1382
+ A G SPE ++ R+ + G E + G LG++ G E +E
Sbjct: 1296 VEVPSMASSWGGPHFSPEHKELSN--SPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKE 1353
Query: 1383 ELQKGMGTVEGGDQSNPK--SKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESP 1435
+L G +++P K++ +S + + +KA +S + SP
Sbjct: 1354 DLN---GPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSP 1405
Score = 94.7 bits (234), Expect = 6e-19
Identities = 265/1434 (18%), Positives = 488/1434 (34%), Gaps = 199/1434 (13%)
Query: 82 ISTSESSEEEEEAEA---ETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGN- 137
++T SSE +E+ + P L S + SS E + EKAG + N
Sbjct: 1343 MNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSS--ELSPDAVEKAGMSSNQ 1400
Query: 138 SMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQAD 197
S+ P ++P + SA++ + + + + PG+
Sbjct: 1401 SISSPVLDAVP------RTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTP 1454
Query: 198 SSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGAL 257
S + SS D+ PS + ++ S+ E A P P +P++ L
Sbjct: 1455 SRHSLSGSSPGMKDIPRTPS----RGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCL 1510
Query: 258 PPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATP 317
P + E S ++ P G RS+ +S++ L V+ +++P + + +
Sbjct: 1511 TPQR-----ERSGSESSVDQKTVARTPLGQRSRSGSSQE-LDVKPSASPQERSESDSSPD 1564
Query: 318 APPGKAGAVASQTKAGK-PEEDSESS----SEESSDSEEETPAAKALLQAKASGKTSQVG 372
+ + ++++G PE DS+S S S E +A +A++ +S
Sbjct: 1565 SKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEP 1624
Query: 373 AASAPA-------KESPRKGAAPAPPGKTG--------PAVAKAQAGKREEDSQSSSEES 417
A AP S KG P+P G + P A+ G R SS E
Sbjct: 1625 KAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSR------SSPEP 1678
Query: 418 DSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRS 477
++ P + + S +P++ + ++ S ++P +T P + S S
Sbjct: 1679 KTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPR-------HRRSPSVS 1731
Query: 478 SSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQ 537
S E ++ R + +A+ SP+ K S G P P P G + S +
Sbjct: 1732 SPEPAEKSRSSRRRRSAS-------SPRTKTTSRRGRSP-----SPKPRGLQRSRSRSRR 1779
Query: 538 VGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKP------TSSPAKGPPQK 591
++ + D S T+ + +S + + + + SPA+ +
Sbjct: 1780 -------EKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSR 1832
Query: 592 AGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTT 651
+ ++ P + + S + A P + ++A PA P +
Sbjct: 1833 TSSRRRRGRSRTPPTSRKRSRSRTSPA-----PWKRSRSRASPATHRRSRSRTPLISRRR 1887
Query: 652 ASAKVAPV-----RVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKT 706
+ ++ +PV R T R+ + + S T S S +
Sbjct: 1888 SRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSR 1947
Query: 707 GLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSE 766
V + +S ++ + PV + + + + T ++ S +S
Sbjct: 1948 SRTPPVTRRRS-------RSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSP 2000
Query: 767 EESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSK 826
+ SP + S +T P A R S T P K +++ RSP
Sbjct: 2001 VTRRRSRSRTSPVTRRRSRSRT-----PPAIRRRSRSRTPLLPRK------RSRSRSPLA 2049
Query: 827 VKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQ 886
++ R+ T ARG S+ A+ + SGSS + S S T +
Sbjct: 2050 IRRRSRSRTPRT--ARGKRSLTRSPPAIRRRSA--------SGSSSDRSRSATPPAT--R 2097
Query: 887 VKPSGKTHQIRAALAPAKESPRKGAAPTP------PGKTGPSAA---------QAGKQ-- 929
+T + + R +PTP PG P + QAG
Sbjct: 2098 NHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMM 2157
Query: 930 --------DDSGSSSEESDSDGEAPAAVTSAQV--IKPPLIFVDPNRSPAGPAATPAQAQ 979
D +S E+ + A+T+ + +PP P+ S AG AA +Q
Sbjct: 2158 DGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPP-----PSMSAAGLAARMSQVP 2212
Query: 980 AASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAG 1039
A R + + +S + + TP I T V + P A ++A
Sbjct: 2213 APVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLAS 2272
Query: 1040 ASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQAT 1099
++ S ++ + A V+ A PA + S+ GT A
Sbjct: 2273 PRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALA-ALSLTGSGTPPT----------AA 2321
Query: 1100 KAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVV 1159
P SS PQ SA+ LVGP + V + ++ +
Sbjct: 2322 NYPSSS-----------------RTPQAPASAN-LVGPRSAHATAPVNIAGSRTAA--AL 2361
Query: 1160 APSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGML 1219
AP+ SL S M P L+ AN + + S ++ D + + M
Sbjct: 2362 APA-SLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMT 2420
Query: 1220 SPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVV 1279
S + + G P +S P P++ + S+ ++CL+ Q P+ +Q +S
Sbjct: 2421 SERAPSPSSRMGQAPSQSLLPP-AQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGA 2479
Query: 1280 KVLTELLEQERKKVVDTTKESSRKGWESRKRKLSG-DQPAARTPRSKKKKKLGAGEGGEA 1338
T + ++ +G QP+A K++ + +
Sbjct: 2480 VATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSS 2539
Query: 1339 SVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAK--DEPEEELQKGMGTVEGGDQ 1396
S S +S++S + +S D S+G+ +PE L++ +
Sbjct: 2540 SSSSSSSSSSSSSSSSSGSSSSD-----------SEGSSLPVQPEVALKRVPSPTPAPKE 2588
Query: 1397 SNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1450
+ + + + KRK+ + +S+ S S S ++ +
Sbjct: 2589 AVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642
Score = 94.7 bits (234), Expect = 6e-19
Identities = 261/1317 (19%), Positives = 459/1317 (34%), Gaps = 212/1317 (16%)
Query: 88 SEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKT 147
S E +A +T + PR S +S L + +E++ +E+ KT P +
Sbjct: 1482 SSPEPKALPQTPR--PRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSR- 1538
Query: 148 VANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSS- 206
SG S +PSA+ E E S P A + + ++ SS E S S
Sbjct: 1539 -----SGSSQELDVKPSASP---QERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSR 1590
Query: 207 --------SDETDVEGKPSVKP-AQVKASSVSTKESPARKAAPAPGKVGDVT----PQVK 253
+V+ KP P AQ + S ++PA +A P + G + P +
Sbjct: 1591 LSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPE 1650
Query: 254 GGALPPAKRAKKPEEESESSEEGSESEEEAPA---------GTRSQVKASEKILQVRAAS 304
G + + P+ S ++ GS S E +RS + + K R +
Sbjct: 1651 GSSSTESSPEHPPK--SRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSR 1708
Query: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEET----------- 353
+ + + TP ++ +V+S +P E S SS S S T
Sbjct: 1709 SASSSPETRSRTPPRHRRSPSVSSP----EPAEKSRSSRRRRSASSPRTKTTSRRGRSPS 1764
Query: 354 PAAKALLQAKASGKTSQV---------GAASAPAKESPR-KGAAPAPPGKTGPAVAKAQA 403
P + L ++++ + + G++ + ++ R + + + G + +++
Sbjct: 1765 PKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRS 1824
Query: 404 GKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAA 463
R+E S++SS P ++ K + R + AP K S R A+PA R++
Sbjct: 1825 PARQESSRTSSRRRRGRSRTPPTSR---KRSRSRTSPAPWKRS-RSRASPATHRRSRSRT 1880
Query: 464 AQVQVGKQEEDS------RSSSEESDSDREALA-AMNAAQVKPLGKSPQVKPASTMGMGP 516
+ + + RS S S + R + + A ++ + ++P V + P
Sbjct: 1881 PLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTP 1940
Query: 517 LGKGAG-----PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKS 571
+ PV + TP + + + S S V + ++
Sbjct: 1941 TTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSP 2000
Query: 572 LGNILQAKPTSSPAKGPPQKAGPVAVQVKAEK-----PMDNSESSE-----ESSDSADSE 621
+ TS + + P A++ ++ P S S S S
Sbjct: 2001 VTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPR 2060
Query: 622 EAPAAMTAAQAKPALKIPQTK---------ACPKKTNTTASAKVAPVRVGTQ-------- 664
A + ++ PA++ A P T + ++ PV + +
Sbjct: 2061 TARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRP 2120
Query: 665 --APRKAGTATSP------------------AGSSPAVAGGTQRPAEDSSSSEESDSEEE 704
+P SP AG S G + P +S E+ ++
Sbjct: 2121 SMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQS- 2179
Query: 705 KTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSES 764
+ LA+T + + AA + + S P++ +T P A + + +
Sbjct: 2180 RIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANL--ASRIPAASA 2237
Query: 765 SEEESDSEEAAASPAQVKTSVKKTQAKA------NPAAARAPSAKG-----TISAP---- 809
+ S A P V + +T A A +P A APSA T +AP
Sbjct: 2238 AAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNL 2297
Query: 810 -GKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS 868
G AA A + S P N +S+ + PAS VG A A T P +
Sbjct: 2298 AGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHA----TAPVNIA 2353
Query: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP------GKTGPS 922
GS + + T A++ P+ + + P R +PP +T PS
Sbjct: 2354 GSRTAAALAPASL-TSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPS 2412
Query: 923 AAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQ--- 979
A + + S S G+AP+ Q + PP D RSP P+A Q++
Sbjct: 2413 APSQSRMTSERAPSPSSRM-GQAPS-----QSLLPPA--QDQPRSPV-PSAFSDQSRCLI 2463
Query: 980 AASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVV---------TMPTAHPR 1030
A +TP S S+ +++ S D PG+ + V P+A
Sbjct: 2464 AQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAA 2523
Query: 1031 IAP---------------KASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQ 1075
+ P +S + +SSS SS S EG + V V SP
Sbjct: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT 2583
Query: 1076 STSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLV 1135
+A + +P + ++ + + SS S SS SSS S + S+
Sbjct: 2584 PAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS---- 2639
Query: 1136 GPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPK----LDSS 1191
+++ SS P L +P P + S++ K L S
Sbjct: 2640 -----------SSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDS 2688
Query: 1192 PSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQ 1248
S+S + + P + + QQ++ S + G + G + S K ++ +P+
Sbjct: 2689 RSLSYSPVERRRPSPQPSPRDQQSS---SSERGSRRGQRGDSRSPSHKRRRETPSPR 2742
Score = 92.8 bits (229), Expect = 2e-18
Identities = 260/1474 (17%), Positives = 506/1474 (34%), Gaps = 197/1474 (13%)
Query: 66 EEDAALQAKK--TRVSDPISTSESSEEEEEA--------EAETAKATPRLASTNSSVLGA 115
E D +L K+ TR S S+ S + E+A + A PR S S +
Sbjct: 1364 ETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSAS 1423
Query: 116 DLPSSMKEKAKAETEKAGKTGNSMP-HPATGKTVANLLSGKSPRKSAEPSANTTLVSETE 174
MK+ + ++G+S +G + LSG SP P + SE +
Sbjct: 1424 S--PEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECD 1481
Query: 175 EEGSVPAFGAAAKPGMVSAGQADSSSE----DTSSSSDETDVEGKPSVK-PAQVKASSVS 229
A +P S + +++ S E+ V+ K + P ++ S S
Sbjct: 1482 SSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGS 1541
Query: 230 TKESPAR-KAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTR 288
++E + A+P D +P K P ++ + E + S + +G+
Sbjct: 1542 SQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSS 1601
Query: 289 SQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSD 348
+VK + A + G ++P P A + S E S
Sbjct: 1602 PEVKDKPR--------AAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSS 1653
Query: 349 SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREE 408
S E +P + +T++ G+ S+P ++ + ++ P + + R
Sbjct: 1654 STESSP------EHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRS 1707
Query: 409 DSQSSSEESDSEEEAPAQAKPSGKAPQV----------RAASAP-AKESPRKGAAPAPPR 457
S SSS E+ S + PS +P+ R+AS+P K + R+G +P+P
Sbjct: 1708 RSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKP 1767
Query: 458 KTGPAAAQVQVGKQEEDSRSSSEESDSDRE---ALAAMNAAQVKPLGKSPQVKPASTMGM 514
+ G Q SRS E++ + R + ++ + ++ + +S G
Sbjct: 1768 R----------GLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRG- 1816
Query: 515 GPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVP-----TAVAPA-Q 568
G G P + + S++ + + +S + S S P + +PA
Sbjct: 1817 ---GSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATH 1873
Query: 569 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMT 628
+S S ++ P + + S +S S + S P
Sbjct: 1874 RRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRR 1933
Query: 629 AAQAK-PALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQ 687
++++ P + P T + ++ PV R++ + TSP T+
Sbjct: 1934 RSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPV-----TRRRSRSRTSPI---------TR 1979
Query: 688 RPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL---QVKAASVPVKGSLGQGTAPVLP 744
R + +S +T VT +++S + + ++ + P + P+LP
Sbjct: 1980 RRSRSRTSPVTRRRSRSRTS-PVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLP 2038
Query: 745 GKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKT-----SVKKTQAKANPAAARA 799
K + + + ++ S + SP ++ S A P A R
Sbjct: 2039 RKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRN 2098
Query: 800 PSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQ 859
S T P + ++ + PS P+ ++ +L +S +
Sbjct: 2099 HSGSRT---PPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGS 2155
Query: 860 AQTGPEEDSGSSEEESDSEEEAET---LAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP 916
GP + S E A++ LA S T + +++ A + R P P
Sbjct: 2156 MMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPV 2215
Query: 917 G----KTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPA 972
+T P AA + + S++ + + PA T+ + +R+PA A
Sbjct: 2216 PLMSLRTAP-AANLASRIPAASAAAMNLASARTPAIPTAVNLAD--------SRTPAAAA 2266
Query: 973 A----TPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLT-PGIRTNVVTMPTA 1027
A +P A A S A TA + + A LT G P++
Sbjct: 2267 AMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSS 2326
Query: 1028 H--PRIAPKASMAGASSSKESSRISDGKKQEGPA--------TQVDSAVGTLPATSPQ-S 1076
P+ A++ G S+ ++ ++ + A ++ A+ TSP+
Sbjct: 2327 SRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVP 2386
Query: 1077 TSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVG 1136
S + + + P L + T S S + S S G+ P + +L+
Sbjct: 2387 LSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAP-----SQSLLP 2441
Query: 1137 PTPSRTETLVEETAAESS-----EDDVVAPSQSLLSGYMTPGLTPAN------SQASKAT 1185
P + + V ++ S + VA SQSL SG + + A S +
Sbjct: 2442 PAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGV 2501
Query: 1186 PKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAG 1245
P D +ST A + + ++ + S + ++S ++ S +
Sbjct: 2502 PHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSS 2561
Query: 1246 NPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGW 1305
+ + S+L +Q + + P P KE+ R+G
Sbjct: 2562 DSEGSSLPVQPEVALKRVPSPTP---------------------------APKEAVREG- 2593
Query: 1306 ESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKE- 1364
+P TP +K++ + +S S +S++S + +S
Sbjct: 2594 ----------RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
Query: 1365 ---------KKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRK--- 1412
K G +L + +P ++ + D ++R+
Sbjct: 2644 SSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSP 2703
Query: 1413 ----KDKEKKEKKKKAKKASTKDSESPSQKKKKK 1442
+D++ ++ +++ DS SPS K++++
Sbjct: 2704 QPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRE 2737
Score = 75.9 bits (185), Expect = 3e-13
Identities = 179/960 (18%), Positives = 314/960 (32%), Gaps = 64/960 (6%)
Query: 60 GRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLA------STNSSVL 113
G +R + + TR D +S+S+ + ++ T R S + +
Sbjct: 1769 GLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQ 1828
Query: 114 GADLPSSMKEKAKAETEKAG-KTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSE 172
+ SS + + ++ T K S PA K + S + R+S + T L+S
Sbjct: 1829 ESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSR---SRTPLISR 1885
Query: 173 TEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKE 232
S + S S S S P V + ++ + +T+
Sbjct: 1886 RRSRSRTSPVSRRRSRSRTSVTRRRSRSR-ASPVSRRRSRSRTPPVTRRRSRSRTPTTRR 1944
Query: 233 SPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVK 292
+ P VT + PP R + S + S S RS+ +
Sbjct: 1945 RSRSRTPP-------VTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSR 1997
Query: 293 ASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES--SDSE 350
S + + R+ S + T + + PP S+T P + S S S + S
Sbjct: 1998 TSP-VTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPL-LPRKRSRSRSPLAIRRRSR 2055
Query: 351 EETP-AAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG---PAVAKAQAGKR 406
TP A+ S + +AS + + R PA +G P VA +
Sbjct: 2056 SRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMS 2115
Query: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV 466
S S +P +P G + + A S G P P
Sbjct: 2116 CFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIP---------- 2165
Query: 467 QVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPP 526
+ R+S E+ + A+ A + P + A + + PVP
Sbjct: 2166 ------DHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAAR--MSQVPAPVPL 2217
Query: 527 GKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKS---LGNILQAKPTSS 583
+ A P+A + + +++ + + +PTAV A ++ + A P ++
Sbjct: 2218 MSLRTA-PAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTA 2276
Query: 584 PAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKA 643
A A P A + ++ S P TAA + + PQ A
Sbjct: 2277 VAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPP--TAANYPSSSRTPQAPA 2334
Query: 644 CPKKTNTTASAKVAPVRVGTQ--APRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDS 701
++ APV + A A + + A +PA++G S+ E S
Sbjct: 2335 SANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVS 2394
Query: 702 EEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQED 761
L + + S P + + AP + G +Q +D
Sbjct: 2395 GRTSPPL---------LDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQD 2445
Query: 762 SESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQ 821
S S + + T V +Q+ ++ A A S+ G + V
Sbjct: 2446 QPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSD 2505
Query: 822 RSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEA 881
+ P L S + ++++ + + S SS S S+ E
Sbjct: 2506 VGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEG 2565
Query: 882 ETLAQVKPSGKTHQIRAALAPAKESPRKG--AAPTPPGKTGPSAAQAGKQDDSGSSSEES 939
+L V+P ++ + KE+ R+G PTP + S++ + S SSS S
Sbjct: 2566 SSLP-VQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSS 2624
Query: 940 DSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSS 999
S + ++ +S+ P+ + GP A P A P R S S + S
Sbjct: 2625 SSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDS 2684
Score = 71.6 bits (174), Expect = 5e-12
Identities = 121/513 (23%), Positives = 191/513 (37%), Gaps = 66/513 (12%)
Query: 43 PVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRV-SDPISTSESSEEEEEAEAETAKA 101
PV L+ + T + L + A AA+ R + P + + + A A A
Sbjct: 2214 PVPLMSLRT--APAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLA 2271
Query: 102 TPRLASTNSSVLGAD--LPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRK 159
+PR A S+V AD P++ A S+ T T AN S +
Sbjct: 2272 SPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSS---R 2328
Query: 160 SAEPSANTTLVSETEEEGSVPA-------FGAAAKPGMVSAGQADSSSEDTSSS-----S 207
+ + A+ LV + P A A + SA A + S +S S
Sbjct: 2329 TPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLS 2388
Query: 208 DETDVEGKPSVKPAQVKASSVSTKESPAR-----KAAPAPG-KVGDVTPQVKGGALPPAK 261
V G+ S P +A S + +P++ + AP+P ++G Q LPPA+
Sbjct: 2389 AYERVSGRTS-PPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQ---SLLPPAQ 2444
Query: 262 ---RAKKPEEESESSE---------EGSES-EEEAPAGTRSQVKASEKILQVRAASAPAK 308
R+ P S+ S GS+S A A T S +L V A P
Sbjct: 2445 DQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHS 2504
Query: 309 --GTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASG 366
G P P A+ + S SSS SS S + ++ + + S
Sbjct: 2505 DVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE 2564
Query: 367 KTS----------QVGAASAPAKESPRKGAAPAP-PGKTGPAVAKAQAGKREEDSQSSSE 415
+S +V + + KE+ R+G P P P K + + + S SSS
Sbjct: 2565 GSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSS 2624
Query: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDS 475
S S + + + S + ++ +PAK P+ PA P+K P E S
Sbjct: 2625 SSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG---------ERRS 2675
Query: 476 RSSSEESDSDREALAAMNAAQVKPLGKSPQVKP 508
RS + DS R++ +++ + V+ SPQ P
Sbjct: 2676 RSPRKPIDSLRDS-RSLSYSPVERRRPSPQPSP 2707
Score = 70.1 bits (170), Expect = 1e-11
Identities = 104/464 (22%), Positives = 164/464 (35%), Gaps = 44/464 (9%)
Query: 26 AAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTS 85
AA + S + V L D T L R AAL + +
Sbjct: 2264 AAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANY 2323
Query: 86 ESSEEEEEAEAETAKATPRLASTNSSV-------LGADLPSSMKEKAKAET-EKAGKTGN 137
SS +A A PR A + V A P+S+ A A T
Sbjct: 2324 PSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSP 2383
Query: 138 SMPHPA----TGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSA 193
+P A +G+T LL R + + + SE S G A ++
Sbjct: 2384 RVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPS-SRMGQAPSQSLLPP 2442
Query: 194 GQADSSSEDTSSSSDE--------TDVEGKPSVKPAQVKASSVSTKESPARKAAPAPG-- 243
Q S S+ SD+ T V G S+ V ++ S + + PAPG
Sbjct: 2443 AQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP 2502
Query: 244 --KVGDVTPQVKGGALPPAKRAKKPEEE---SESSEEGSESEEEAPAGTRSQVKASEKIL 298
VG+ P G P A A +P +E S SS S S + + + S +
Sbjct: 2503 HSDVGE-PPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSS 2561
Query: 299 QVRAASAPAKGTPGKGATPAP-PGKAGAV----------ASQTKAGKPEEDSESSSEESS 347
+S P + P+P P AV A + + S SSS SS
Sbjct: 2562 DSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSS 2621
Query: 348 DSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKRE 407
S + ++ + + +S +S ++ +PAK P+ PA P K P ++++ ++
Sbjct: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKP 2681
Query: 408 EDSQSSSEESDSEEEAPAQAKPSGKAPQVR-AASAPAKESPRKG 450
D S +S S +P + + P R S+ ++ R+G
Sbjct: 2682 ID---SLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRG 2722
Score = 60.8 bits (146), Expect = 9e-09
Identities = 131/705 (18%), Positives = 234/705 (33%), Gaps = 97/705 (13%)
Query: 816 AAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGP--EEDSGSSEE 873
A +AKQ +P KP ++S+ + P K + P E S ++
Sbjct: 157 AREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKK 216
Query: 874 ESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSG 933
+ SE E++ P+ K+ + +K+ RK + T P A ++ D S
Sbjct: 217 KHRSESESKKRKHRSPTPKSKR------KSKDKKRKRSRSTTPAPKSRRAHRSTSAD-SA 269
Query: 934 SSSEESDSDGEAPAAVTSAQVI--KPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASE 991
SSS+ S S + AA T + + P P G P ++ ++ + E
Sbjct: 270 SSSDTSRSRSRSAAAKTHTTALAGRSP----SPASGRRGEGDAPFSEPGTTSTQRPSSPE 325
Query: 992 STARSSSSESEDEDVIPATQCLT-----PGIRTNVVTMPTAHPRIAPK------------ 1034
+ + SS ED+D + T P + P P +A +
Sbjct: 326 TATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTP 385
Query: 1035 ASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPE 1094
S + E+S D + P S+ SPQ T V ++ PK
Sbjct: 386 LSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPK--- 442
Query: 1095 VQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETA-AES 1153
AP E SS +S + G + +HT PSR A A+
Sbjct: 443 -----PAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHT-----PSRRMGRSRSPATAKR 492
Query: 1154 SEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQ 1213
P++ S +P + S + SP + P + Q
Sbjct: 493 GRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSR---SPQRRGRSRSPQRPGWSRSRNTQ 549
Query: 1214 QAAGMLSPKTGGKEAASGTTP-------------QKSRKPKKGAGNPQASTLALQSNITQ 1260
+ S + G + S T +SR P + + T + T
Sbjct: 550 RRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTP 609
Query: 1261 CLLGQP---WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQP 1317
G+ P S V+ + R+ ++ +R+G + +
Sbjct: 610 ARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRS 669
Query: 1318 AARTPR---SKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKA----------SGDVKE 1364
+RTP + + + A G S +P + + S+ +R ++ SG E
Sbjct: 670 RSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSE 729
Query: 1365 KKGKGSLGSQGAKDEPEEELQKG-MGTVEGGDQSNPKSK------------------KEK 1405
+K K + ++ E++K + + S+P+SK K+K
Sbjct: 730 RKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQK 789
Query: 1406 KKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1450
++ R+ + K K++ + S S K+K K + Q+
Sbjct: 790 SQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQS 834
Score = 52.0 bits (123), Expect = 4e-06
Identities = 62/279 (22%), Positives = 114/279 (40%), Gaps = 45/279 (16%)
Query: 1171 TPGLTPANSQA-------SKATPKLDSSPSVSSTLA--AKDDPDGKQEAKPQQAAGMLSP 1221
TPG PA ++ K +L ++ +S + + DP + Q A P
Sbjct: 111 TPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKP 170
Query: 1222 KTGGKEAASGTTP---QKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASV 1278
+ +E++S +P QK +K KK G S+ P E + +
Sbjct: 171 YSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSS---------------PRRERKKSSKK 215
Query: 1279 VKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEA 1338
K +E E +++K T +S RK + ++++ PA P+S++ + + + +
Sbjct: 216 KKHRSES-ESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPA---PKSRRAHRSTSADSASS 271
Query: 1339 SVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSN 1398
S + S ++ K +G + + G +G D P E GT S+
Sbjct: 272 SDTSRSRSRSAAAKTHTTALAG----RSPSPASGRRGEGDAPFSE----PGTTSTQRPSS 323
Query: 1399 PKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQ 1437
P++ ++ S KDK+KKE K++T+ S SP +
Sbjct: 324 PETATKQPSSPYEDKDKDKKE------KSATRPSPSPER 356
Score = 42.4 bits (98), Expect = 0.003
Identities = 33/144 (22%), Positives = 63/144 (43%), Gaps = 7/144 (4%)
Query: 1309 KRKLSGDQPAARTPRS------KKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDV 1362
K + G +PA KK ++L A G S + +S + +A+ K
Sbjct: 108 KEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYV-DGSSFDPQRRAREAKQPAPE 166
Query: 1363 KEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKK 1422
K S ++ ++ +K G + ++E+KKS K+KK + + E KK
Sbjct: 167 PPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKK 226
Query: 1423 KAKKASTKDSESPSQKKKKKKKKT 1446
+ ++ T S+ S+ KK+K+ ++
Sbjct: 227 RKHRSPTPKSKRKSKDKKRKRSRS 250
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 122 bits (307), Expect = 2e-27
Identities = 317/1444 (21%), Positives = 506/1444 (35%), Gaps = 222/1444 (15%)
Query: 85 SESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP-- 142
S+ SEEE A L + A+ PS M K + ++ K P P
Sbjct: 46 SQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPS-MHRKQELDSSHPPKQSGRPPDPGR 104
Query: 143 ------ATGKTVANL-----LSGKSPRK-SAEPSANTTLVSETEEEGSVPAF-----GAA 185
+ +T L G+SP S + S + T + E + +P F +
Sbjct: 105 PAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALS 164
Query: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKV 245
A +V+ D+ +S +ET + K V+ Q K + + P P +
Sbjct: 165 AVSSVVNKFNPFDLISDSEASQEETTKKQKV-VQKEQGKPEGIIKPPLQQQPPKPIPKQQ 223
Query: 246 GDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASA 305
G ++ P + +++PE+ +S G+ + P T A K+ R AS
Sbjct: 224 GPGRDPLQQDGTPKSISSQQPEK-IKSQPPGTGKPIQGPTQTPQTDHA--KLPLQRDASR 280
Query: 306 P----AKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQ 361
P A G+ P+ P + Q GKP + E+S + PA
Sbjct: 281 PQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQ-QPGHEKSQPGPAKPPA------ 333
Query: 362 AKASGKTSQVGAASAPAKESPRKGAAPA-PPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Q + P + P P PPG T P A+ + Q+ SE+ SE
Sbjct: 334 --------QPSGLTKPLAQQPGTVKPPVQPPGTTKPP-AQPLGPAKPPAQQTGSEKPSSE 384
Query: 421 EEAP-AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSS 479
+ P A A+P G PAK ++ P P + Q G Q
Sbjct: 385 QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ--------QPGLQSPAKAPGP 436
Query: 480 EESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVG 539
++ + + A Q P GK+ + T L A P PP + GPA P Q
Sbjct: 437 TKTPVQQPGPGKIPAQQAGP-GKTSAQQTGPTKPPSQLPGPAKP-PPQQPGPAKPPPQ-- 492
Query: 540 KWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQV 599
+ + S P PA+ Q ++ P P A P A Q
Sbjct: 493 ---QPGSAKPPSQQPGSTKPPPQQPGPAKPSP-----QQPGSTKPPSQQPGSAKPSAQQP 544
Query: 600 KAEKP-MDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAP 658
KP S + S + P +A+ P+ +P+T CP NTT
Sbjct: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKT-ICP-LCNTT------- 595
Query: 659 VRVGTQAPRKA--GTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAK 716
+ P KA T T + ++ G P E K L + +
Sbjct: 596 -ELLLHVPEKANFNTCTECQTTVCSLCGFNPNP----------HLTEVKEWLCLNCQMKR 644
Query: 717 SVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAA 776
++G L A VP ++P KT P T K S + + S + A
Sbjct: 645 ALGGDL----APVP--------SSPQPKLKTAPVTTTSAVSK----SSPQPQQTSPKKDA 688
Query: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN 836
+P Q + K + K P + P+ G+ SA K A + +P K +P V + Q+
Sbjct: 689 APKQDLS--KAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK-EPSVPSEQD 745
Query: 837 STVLARGPASVPSVGKA---VATAAQAQTGPEEDSGSSEEESDSEEEAE---TLAQVKPS 890
+A P + K + +++ A T P D SS+ +S +EE+ KPS
Sbjct: 746 KAPVADDKPKQPKMVKPTTDLVSSSSATTKP--DIPSSKVQSQAEEKTTPPLKTDSAKPS 803
Query: 891 GKTHQIRAALAP--AKESPRKGAAPTPPGKTGPSAAQAG-KQDDSGSSSEESDSDGEAPA 947
++P +K PR + GPS+ G KQ D EE +A
Sbjct: 804 QSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK---KAQT 860
Query: 948 AVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVI 1007
++ KP P SP P P Q TP+++ + +R S
Sbjct: 861 KMSPKPDAKPM-----PKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDA 915
Query: 1008 PATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVG 1067
P +Q TP + K GAS ++S + Q GP +Q
Sbjct: 916 PKSQPTTP------------QETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP 963
Query: 1068 TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQG 1127
A +P S ++G K QA AP S + + + + + + + Q
Sbjct: 964 MKQAPAP-SQPPTSQGPPK-------STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQ- 1014
Query: 1128 AKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPK 1187
PT RTET + + S+ P +++L P + S PK
Sbjct: 1015 --------APTVKRTETEKKPPPIKDSKSLTAEPQKAVL---------PTKLEKS---PK 1054
Query: 1188 LDSSPSVSST---LAAKDDPDGK--QEAKPQ--------------QAAGMLSPKTGGKEA 1228
+S+ + T + +KD P+ E K Q + L + A
Sbjct: 1055 PESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRA 1114
Query: 1229 ASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPL-----NEAQVQASVVKVL- 1282
SG + P +G P+AS + + + + P + E +V+ KV+
Sbjct: 1115 ISGQLGDIRKMPPAPSG-PKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVIL 1173
Query: 1283 ---TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKK----KKKLGAGEG 1335
E L E+ + TT + + + K K S Q P KK ++K+ + E
Sbjct: 1174 EKVKETLSMEKIPPMVTTDQKQEES-KLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEK 1232
Query: 1336 ----GEASVSPE--------KTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEE 1383
E +PE KTS + K K+ + E+K +G + + + E ++
Sbjct: 1233 KPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQ-EGKQP 1291
Query: 1384 LQKGMGTVEGGDQSNPKSKKEKKKSDKRK-------KDKEKKEKKKKAKKASTKDSESPS 1436
K G G QS PK + K+ K + K + + K+K +K K S S
Sbjct: 1292 QTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSS 1351
Query: 1437 QKKK 1440
Q+ K
Sbjct: 1352 QQPK 1355
Score = 121 bits (303), Expect = 6e-27
Identities = 317/1498 (21%), Positives = 516/1498 (34%), Gaps = 280/1498 (18%)
Query: 80 DPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSM 139
D IS SE+S+EE T K + G P ++ K ++ G + +
Sbjct: 177 DLISDSEASQEE------TTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPL 230
Query: 140 PHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSS 199
T K++++ K KS P + T+ P A P Q D+S
Sbjct: 231 QQDGTPKSISSQQPEKI--KSQPPGTGKPIQGPTQ----TPQTDHAKLPL-----QRDAS 279
Query: 200 SEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPP 259
T + D+ SVKP S S + P ++ P PGK PP
Sbjct: 280 RPQTK----QADIVRGESVKP-----SLPSPSKPPIQQ--PTPGK-------------PP 315
Query: 260 AKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASA-PAKGTPGKGATPA 318
A+ + G E + PA +Q K L + + P PG PA
Sbjct: 316 AQ------------QPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363
Query: 319 PP-GKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKT--------- 368
P G A A QT + KP E P KAL Q GKT
Sbjct: 364 QPLGPAKPPAQQTGSEKPSS--------------EQPGPKALAQPPGVGKTPAQQPGPAK 409
Query: 369 ---SQVGA----ASAPAKESPRKGAAPA--PPGKTGPAVAKAQ-AGKREEDSQSS----- 413
QVG A P +SP K P P + GP AQ AG + +Q +
Sbjct: 410 PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469
Query: 414 -SEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAA-AQVQVGKQ 471
S+ + P Q P+ PQ ++ P + P G+ PP++ GPA + Q G
Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP--GSTKPPPQQPGPAKPSPQQPGST 527
Query: 472 EEDSRSSSEESDSDREALAAMNAAQ--VKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKV 529
+ S+ S ++ A +AQ KP+ ++ KP + P K PP +
Sbjct: 528 KPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQ----PPSQG 583
Query: 530 GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPA---------------------Q 568
P T + E E+++ ++ E T V
Sbjct: 584 LPKT-ICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQM 642
Query: 569 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMT 628
+++LG L P+S P K PV K + + D+A ++ A
Sbjct: 643 KRALGGDLAPVPSSPQ---PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPE 699
Query: 629 AAQAKPALKIPQTKACPKKTNTTASAKVAPVR--VGTQAPRKAGTATSPAGSSPAVAGGT 686
+ P +K P P +A AK P + AP K + S +P
Sbjct: 700 PKKPPPLVKQPTLHGSP-----SAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKP 754
Query: 687 QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPG- 745
++P +++ S T + + +S + + + P+K + + P
Sbjct: 755 KQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAE----EKTTPPLKTDSAKPSQSFPPTG 810
Query: 746 -KTGPTVTQVKAEKQEDSESSEEESDSEEAAAS----PAQVKTSVKKTQAKANPAAARAP 800
K P ++ DS+ S E+ P Q K KK Q K +P P
Sbjct: 811 EKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKP 870
Query: 801 SAKGTISAPGKVVTAA--AQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAA 858
KG+ + PG TA Q+SP + R N + P S P+ T
Sbjct: 871 MPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT------TPQ 924
Query: 859 QAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT---P 915
+ TG G+S S + T Q P H AP K++P PT P
Sbjct: 925 ETVTGKLFGFGASIF-SQASNLISTAGQPGP----HSQSGPGAPMKQAPAPSQPPTSQGP 979
Query: 916 PGKTG-----PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAG 970
P TG P+ + K++ ++E+ + E V + K P P +
Sbjct: 980 PKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP----PPIKDSKS 1035
Query: 971 PAATPAQAQAASTPRKARASESTARSSSSE-----SEDEDVIPATQCL-----------T 1014
A P +A + K+ EST +E + + T+C T
Sbjct: 1036 LTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPT 1095
Query: 1015 P--------------------GIRTNVVTMPTAH--PRIAPKASMAGASSSKES--SRIS 1050
P G ++ MP A P+ +P +SS K + ++
Sbjct: 1096 PHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVK 1155
Query: 1051 DGKKQEGPA-TQVDSAVG-------TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1102
KKQE T+ + + ++ P T+ Q + +KL K K +Q+ P
Sbjct: 1156 LVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLP 1215
Query: 1103 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEE--TAAESSEDDVVA 1160
E + EE+ + K PTP + L E +A E + D++
Sbjct: 1216 E---------EKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLK 1266
Query: 1161 PSQSLLSGYMTPGLTPANSQASKATP-KLDSSPSVS----------STLAAKDDPDGKQE 1209
+ + + P Q K K++ PS + +T K+ P
Sbjct: 1267 SQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCT 1326
Query: 1210 AKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPL 1269
AKP Q KT ++ S T+ + K +G + S+ + S++ + + P
Sbjct: 1327 AKPDQVEPG-KEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGE--IPSLIPT 1383
Query: 1270 NEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSG------DQPAARTPR 1323
+E + + K D+ + S S KL + A+
Sbjct: 1384 DEKDILKGLKK--------------DSFSQESSPSSPSDLAKLESTVLSILEAQASTLAD 1429
Query: 1324 SKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEE 1383
K +KK E VSPE+ K ++ + + E++ K S ++E ++
Sbjct: 1430 EKSEKKTQPHE-----VSPEQPKDQEKTQSLSETLEITISEEEIKES------QEERKDT 1478
Query: 1384 LQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKK 1441
+K Q P SK K+KS+ ++E +++S ++ Q+K++
Sbjct: 1479 FKKD------SQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRR 1530
Score = 60.8 bits (146), Expect = 9e-09
Identities = 136/686 (19%), Positives = 236/686 (34%), Gaps = 100/686 (14%)
Query: 73 AKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMK-EKAKAETEK 131
++KT V + + E+E + EAE + + + + + K E++K E +K
Sbjct: 1145 SQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDK 1204
Query: 132 AGKTGNSMPHPATGKTVAN-----------LLSGKSPR---KSAEPSANTTLVSETEEE- 176
A P P K + LL K P K P A T+ E + +
Sbjct: 1205 ASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDL 1264
Query: 177 -GSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQV-KASSVSTKESP 234
S G V+ + +T +EG PS P + K +TK
Sbjct: 1265 LKSQVQIAEEKLEGRVAPKTVQEGKQP------QTKMEGLPSGTPQSLPKEDDKTTKTIK 1318
Query: 235 ARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKAS 294
+ P K V P +K E+E + S+ S + ++P G +S
Sbjct: 1319 EQPQPPCTAKPDQVEPG-----------KEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSS 1367
Query: 295 EKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETP 354
+ I + G+ + P + + K +E S SS + + E
Sbjct: 1368 DGI----------SSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLES--- 1414
Query: 355 AAKALLQAKASGKTSQVGAASA-PAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSS 413
++L+A+AS + P + SP + P KT + EE+ + S
Sbjct: 1415 TVLSILEAQASTLADEKSEKKTQPHEVSPEQ---PKDQEKTQSLSETLEITISEEEIKES 1471
Query: 414 SEE------SDSEEEAPAQAKPSGKAPQV------RAASAPAKESPRKGAAPAPPRKTGP 461
EE DS+++ P+ K+ V R +ES +P P RK
Sbjct: 1472 QEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRT 1531
Query: 462 AAAQVQVGK-QEEDSRSSSEESDSDREALAAMNA--------------AQVKPLGKSPQ- 505
+ + ++EDS+ S EE D R+ + M+A Q+K + S +
Sbjct: 1532 SVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTES 1591
Query: 506 VKPASTMGMGPL--GKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTA 563
K T G G + GK + + W ++ + + +ES + E +
Sbjct: 1592 QKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQ 1651
Query: 564 VAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKA-----EKPMDNSESSEESSDSA 618
+ + G L+ T K + Q K E+P ES +S +
Sbjct: 1652 ESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDR 1711
Query: 619 DSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGS 678
E +++ A+ P + + ++++ S K + +A + P
Sbjct: 1712 SRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPT-- 1769
Query: 679 SPAVAGGTQRPAEDSSSSEESDSEEE 704
EDSS EE EEE
Sbjct: 1770 -----------IEDSSEEEELREEEE 1784
Score = 52.4 bits (124), Expect = 3e-06
Identities = 190/988 (19%), Positives = 330/988 (33%), Gaps = 152/988 (15%)
Query: 79 SDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138
S P ++ + +A AK+ P T + P++ K + KAE K +
Sbjct: 971 SQPPTSQGPPKSTGQAPPAPAKSIPVKKETKA-------PAAEKLEPKAEQAPTVKRTET 1023
Query: 139 MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADS 198
P K +L + P+K+ P T L + E + P G ++
Sbjct: 1024 EKKPPPIKDSKSLTA--EPQKAVLP---TKLEKSPKPESTCPLCKTELNIGSKDPPNFNT 1078
Query: 199 SSEDTSSSSDETDVEGKPSVKPAQV-------KASSVSTKESPARKAAPAPG-------K 244
+E + + P + Q ++S + RK PAP
Sbjct: 1079 CTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMP 1138
Query: 245 VGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAAS 304
V + K P K KK E+E ++ E E+ + + EKI
Sbjct: 1139 VPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKV------KETLSMEKI------- 1185
Query: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364
P T + + K A A Q K PEE EE SEE+ P LL+ K
Sbjct: 1186 -PPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKP----LLEEK- 1239
Query: 365 SGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP 424
P P K AK A + ++ S+ +EE+
Sbjct: 1240 ----------------------KPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLE 1277
Query: 425 AQAKP----SGKAPQVRAASAPA-----------KESPRKGAAPAPPRKTGPAAAQVQVG 469
+ P GK PQ + P+ K + P PP P QV+ G
Sbjct: 1278 GRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKP--DQVEPG 1335
Query: 470 KQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKV 529
K++ + ++ S ++ KSPQ + + G +P +
Sbjct: 1336 KEKTEKEDDKSDTSSSQQP-------------KSPQGLSDTGYSSDGISSSLGEIP--SL 1380
Query: 530 GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPP 589
P + ++D S S+ESS SS ++ E ++ +IL+A+ ++ +
Sbjct: 1381 IPTDEKDILKGLKKD--SFSQESSPSSPSDLAKL-----ESTVLSILEAQASTLADEKSE 1433
Query: 590 QKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 649
+K P V + K + ++S E+ + SEE + + K K + P +
Sbjct: 1434 KKTQPHEVSPEQPKDQEKTQSLSETLEITISEE-EIKESQEERKDTFKKDSQQDIPSSKD 1492
Query: 650 TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEE--------SDS 701
++ + P + +S + +SP V +R + SSSS+E S
Sbjct: 1493 HKEKSEFVDDITTRREPYDSVEESSESENSP-VPQRKRRTSVGSSSSDEYKQEDSQGSGE 1551
Query: 702 EEEKTGLAVTVGQAKSVGKG-----------LQVKAASVPVKGSLGQGTAPVLPGKTGPT 750
EE+ + A G ++ +++ K +G + GK
Sbjct: 1552 EEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRL 1611
Query: 751 VTQVKAEKQEDS--ESSEEESDSEEAAASPAQVKTSVKKTQAK-----ANPAAARAPSAK 803
+ ED+ S + D E SP K +++ R + +
Sbjct: 1612 TRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIE 1671
Query: 804 GTISAPGKVVTAAAQAK-----QRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAA 858
+ K ++Q K P + + G +S+ + T+
Sbjct: 1672 LNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSP 1731
Query: 859 QAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKE--SPRKGAAPTPP 916
+ + +EDS SS E + + A+ +P G L P E S +
Sbjct: 1732 TSVSSLDEDSDSSPSHKKGESKQQRKARHRPHG-------PLLPTIEDSSEEEELREEEE 1784
Query: 917 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 976
+ +Q SSS++S D + A + K P N SP A+
Sbjct: 1785 LLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTP----PSNLSPIEDASPTE 1840
Query: 977 QAQAASTPRKARASESTARSSSSESEDE 1004
+ + A+ + S + S S ES+ E
Sbjct: 1841 ELRQAAEMEELHRSSCSEYSPSIESDPE 1868
Score = 32.3 bits (72), Expect = 3.4
Identities = 61/288 (21%), Positives = 107/288 (37%), Gaps = 19/288 (6%)
Query: 380 ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSG--KAPQVR 437
+ P + A GK G ++ +A K + S+ SS + E Q +P G + P +R
Sbjct: 3483 DMPTRSRRKARVGKYGDSM--TEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIR 3540
Query: 438 AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 497
A E + +AP K G Q E DS + S + S
Sbjct: 3541 ARVDAKVEIIKHISAPEKTYKGGSLGCQT-----EADSDTQSPQYLSATSPPKDKKRPTP 3595
Query: 498 KPLGKSPQVKPASTMGMGPLGKGA-----GPVPPGKVGPATPSAQVGKWEEDSESSSEES 552
+G S ++ ST+ + P + P+ P G A SA V + + S +
Sbjct: 3596 LEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQK 3655
Query: 553 SDSSD-GEVPTA---VAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS 608
D +VP A A ++S+ + PT+ + P + K + M +S
Sbjct: 3656 VLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQY-TEGYTTKGSQTMTSS 3714
Query: 609 ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKV 656
+ ++ + + T Q+ + ++ +TNT A AK+
Sbjct: 3715 GAQKKVKRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKI 3762
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 122 bits (307), Expect = 2e-27
Identities = 317/1444 (21%), Positives = 506/1444 (35%), Gaps = 222/1444 (15%)
Query: 85 SESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP-- 142
S+ SEEE A L + A+ PS M K + ++ K P P
Sbjct: 46 SQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPS-MHRKQELDSSHPPKQSGRPPDPGR 104
Query: 143 ------ATGKTVANL-----LSGKSPRK-SAEPSANTTLVSETEEEGSVPAF-----GAA 185
+ +T L G+SP S + S + T + E + +P F +
Sbjct: 105 PAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALS 164
Query: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKV 245
A +V+ D+ +S +ET + K V+ Q K + + P P +
Sbjct: 165 AVSSVVNKFNPFDLISDSEASQEETTKKQKV-VQKEQGKPEGIIKPPLQQQPPKPIPKQQ 223
Query: 246 GDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASA 305
G ++ P + +++PE+ +S G+ + P T A K+ R AS
Sbjct: 224 GPGRDPLQQDGTPKSISSQQPEK-IKSQPPGTGKPIQGPTQTPQTDHA--KLPLQRDASR 280
Query: 306 P----AKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQ 361
P A G+ P+ P + Q GKP + E+S + PA
Sbjct: 281 PQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQ-QPGHEKSQPGPAKPPA------ 333
Query: 362 AKASGKTSQVGAASAPAKESPRKGAAPA-PPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Q + P + P P PPG T P A+ + Q+ SE+ SE
Sbjct: 334 --------QPSGLTKPLAQQPGTVKPPVQPPGTTKPP-AQPLGPAKPPAQQTGSEKPSSE 384
Query: 421 EEAP-AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSS 479
+ P A A+P G PAK ++ P P + Q G Q
Sbjct: 385 QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ--------QPGLQSPAKAPGP 436
Query: 480 EESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVG 539
++ + + A Q P GK+ + T L A P PP + GPA P Q
Sbjct: 437 TKTPVQQPGPGKIPAQQAGP-GKTSAQQTGPTKPPSQLPGPAKP-PPQQPGPAKPPPQ-- 492
Query: 540 KWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQV 599
+ + S P PA+ Q ++ P P A P A Q
Sbjct: 493 ---QPGSAKPPSQQPGSTKPPPQQPGPAKPSP-----QQPGSTKPPSQQPGSAKPSAQQP 544
Query: 600 KAEKP-MDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAP 658
KP S + S + P +A+ P+ +P+T CP NTT
Sbjct: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKT-ICP-LCNTT------- 595
Query: 659 VRVGTQAPRKA--GTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAK 716
+ P KA T T + ++ G P E K L + +
Sbjct: 596 -ELLLHVPEKANFNTCTECQTTVCSLCGFNPNP----------HLTEVKEWLCLNCQMKR 644
Query: 717 SVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAA 776
++G L A VP ++P KT P T K S + + S + A
Sbjct: 645 ALGGDL----APVP--------SSPQPKLKTAPVTTTSAVSK----SSPQPQQTSPKKDA 688
Query: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN 836
+P Q + K + K P + P+ G+ SA K A + +P K +P V + Q+
Sbjct: 689 APKQDLS--KAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK-EPSVPSEQD 745
Query: 837 STVLARGPASVPSVGKA---VATAAQAQTGPEEDSGSSEEESDSEEEAE---TLAQVKPS 890
+A P + K + +++ A T P D SS+ +S +EE+ KPS
Sbjct: 746 KAPVADDKPKQPKMVKPTTDLVSSSSATTKP--DIPSSKVQSQAEEKTTPPLKTDSAKPS 803
Query: 891 GKTHQIRAALAP--AKESPRKGAAPTPPGKTGPSAAQAG-KQDDSGSSSEESDSDGEAPA 947
++P +K PR + GPS+ G KQ D EE +A
Sbjct: 804 QSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK---KAQT 860
Query: 948 AVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVI 1007
++ KP P SP P P Q TP+++ + +R S
Sbjct: 861 KMSPKPDAKPM-----PKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDA 915
Query: 1008 PATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVG 1067
P +Q TP + K GAS ++S + Q GP +Q
Sbjct: 916 PKSQPTTP------------QETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP 963
Query: 1068 TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQG 1127
A +P S ++G K QA AP S + + + + + + + Q
Sbjct: 964 MKQAPAP-SQPPTSQGPPK-------STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQ- 1014
Query: 1128 AKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPK 1187
PT RTET + + S+ P +++L P + S PK
Sbjct: 1015 --------APTVKRTETEKKPPPIKDSKSLTAEPQKAVL---------PTKLEKS---PK 1054
Query: 1188 LDSSPSVSST---LAAKDDPDGK--QEAKPQ--------------QAAGMLSPKTGGKEA 1228
+S+ + T + +KD P+ E K Q + L + A
Sbjct: 1055 PESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRA 1114
Query: 1229 ASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPL-----NEAQVQASVVKVL- 1282
SG + P +G P+AS + + + + P + E +V+ KV+
Sbjct: 1115 ISGQLGDIRKMPPAPSG-PKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVIL 1173
Query: 1283 ---TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKK----KKKLGAGEG 1335
E L E+ + TT + + + K K S Q P KK ++K+ + E
Sbjct: 1174 EKVKETLSMEKIPPMVTTDQKQEES-KLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEK 1232
Query: 1336 ----GEASVSPE--------KTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEE 1383
E +PE KTS + K K+ + E+K +G + + + E ++
Sbjct: 1233 KPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQ-EGKQP 1291
Query: 1384 LQKGMGTVEGGDQSNPKSKKEKKKSDKRK-------KDKEKKEKKKKAKKASTKDSESPS 1436
K G G QS PK + K+ K + K + + K+K +K K S S
Sbjct: 1292 QTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSS 1351
Query: 1437 QKKK 1440
Q+ K
Sbjct: 1352 QQPK 1355
Score = 121 bits (303), Expect = 6e-27
Identities = 317/1498 (21%), Positives = 516/1498 (34%), Gaps = 280/1498 (18%)
Query: 80 DPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSM 139
D IS SE+S+EE T K + G P ++ K ++ G + +
Sbjct: 177 DLISDSEASQEE------TTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPL 230
Query: 140 PHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSS 199
T K++++ K KS P + T+ P A P Q D+S
Sbjct: 231 QQDGTPKSISSQQPEKI--KSQPPGTGKPIQGPTQ----TPQTDHAKLPL-----QRDAS 279
Query: 200 SEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPP 259
T + D+ SVKP S S + P ++ P PGK PP
Sbjct: 280 RPQTK----QADIVRGESVKP-----SLPSPSKPPIQQ--PTPGK-------------PP 315
Query: 260 AKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASA-PAKGTPGKGATPA 318
A+ + G E + PA +Q K L + + P PG PA
Sbjct: 316 AQ------------QPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363
Query: 319 PP-GKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKT--------- 368
P G A A QT + KP E P KAL Q GKT
Sbjct: 364 QPLGPAKPPAQQTGSEKPSS--------------EQPGPKALAQPPGVGKTPAQQPGPAK 409
Query: 369 ---SQVGA----ASAPAKESPRKGAAPA--PPGKTGPAVAKAQ-AGKREEDSQSS----- 413
QVG A P +SP K P P + GP AQ AG + +Q +
Sbjct: 410 PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469
Query: 414 -SEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAA-AQVQVGKQ 471
S+ + P Q P+ PQ ++ P + P G+ PP++ GPA + Q G
Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP--GSTKPPPQQPGPAKPSPQQPGST 527
Query: 472 EEDSRSSSEESDSDREALAAMNAAQ--VKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKV 529
+ S+ S ++ A +AQ KP+ ++ KP + P K PP +
Sbjct: 528 KPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQ----PPSQG 583
Query: 530 GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPA---------------------Q 568
P T + E E+++ ++ E T V
Sbjct: 584 LPKT-ICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQM 642
Query: 569 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMT 628
+++LG L P+S P K PV K + + D+A ++ A
Sbjct: 643 KRALGGDLAPVPSSPQ---PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPE 699
Query: 629 AAQAKPALKIPQTKACPKKTNTTASAKVAPVR--VGTQAPRKAGTATSPAGSSPAVAGGT 686
+ P +K P P +A AK P + AP K + S +P
Sbjct: 700 PKKPPPLVKQPTLHGSP-----SAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKP 754
Query: 687 QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPG- 745
++P +++ S T + + +S + + + P+K + + P
Sbjct: 755 KQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAE----EKTTPPLKTDSAKPSQSFPPTG 810
Query: 746 -KTGPTVTQVKAEKQEDSESSEEESDSEEAAAS----PAQVKTSVKKTQAKANPAAARAP 800
K P ++ DS+ S E+ P Q K KK Q K +P P
Sbjct: 811 EKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKP 870
Query: 801 SAKGTISAPGKVVTAA--AQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAA 858
KG+ + PG TA Q+SP + R N + P S P+ T
Sbjct: 871 MPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT------TPQ 924
Query: 859 QAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT---P 915
+ TG G+S S + T Q P H AP K++P PT P
Sbjct: 925 ETVTGKLFGFGASIF-SQASNLISTAGQPGP----HSQSGPGAPMKQAPAPSQPPTSQGP 979
Query: 916 PGKTG-----PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAG 970
P TG P+ + K++ ++E+ + E V + K P P +
Sbjct: 980 PKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP----PPIKDSKS 1035
Query: 971 PAATPAQAQAASTPRKARASESTARSSSSE-----SEDEDVIPATQCL-----------T 1014
A P +A + K+ EST +E + + T+C T
Sbjct: 1036 LTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPT 1095
Query: 1015 P--------------------GIRTNVVTMPTAH--PRIAPKASMAGASSSKES--SRIS 1050
P G ++ MP A P+ +P +SS K + ++
Sbjct: 1096 PHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVK 1155
Query: 1051 DGKKQEGPA-TQVDSAVG-------TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1102
KKQE T+ + + ++ P T+ Q + +KL K K +Q+ P
Sbjct: 1156 LVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLP 1215
Query: 1103 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEE--TAAESSEDDVVA 1160
E + EE+ + K PTP + L E +A E + D++
Sbjct: 1216 E---------EKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLK 1266
Query: 1161 PSQSLLSGYMTPGLTPANSQASKATP-KLDSSPSVS----------STLAAKDDPDGKQE 1209
+ + + P Q K K++ PS + +T K+ P
Sbjct: 1267 SQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCT 1326
Query: 1210 AKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPL 1269
AKP Q KT ++ S T+ + K +G + S+ + S++ + + P
Sbjct: 1327 AKPDQVEPG-KEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGE--IPSLIPT 1383
Query: 1270 NEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSG------DQPAARTPR 1323
+E + + K D+ + S S KL + A+
Sbjct: 1384 DEKDILKGLKK--------------DSFSQESSPSSPSDLAKLESTVLSILEAQASTLAD 1429
Query: 1324 SKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEE 1383
K +KK E VSPE+ K ++ + + E++ K S ++E ++
Sbjct: 1430 EKSEKKTQPHE-----VSPEQPKDQEKTQSLSETLEITISEEEIKES------QEERKDT 1478
Query: 1384 LQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKK 1441
+K Q P SK K+KS+ ++E +++S ++ Q+K++
Sbjct: 1479 FKKD------SQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRR 1530
Score = 60.8 bits (146), Expect = 9e-09
Identities = 136/686 (19%), Positives = 236/686 (34%), Gaps = 100/686 (14%)
Query: 73 AKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMK-EKAKAETEK 131
++KT V + + E+E + EAE + + + + + K E++K E +K
Sbjct: 1145 SQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDK 1204
Query: 132 AGKTGNSMPHPATGKTVAN-----------LLSGKSPR---KSAEPSANTTLVSETEEE- 176
A P P K + LL K P K P A T+ E + +
Sbjct: 1205 ASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDL 1264
Query: 177 -GSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQV-KASSVSTKESP 234
S G V+ + +T +EG PS P + K +TK
Sbjct: 1265 LKSQVQIAEEKLEGRVAPKTVQEGKQP------QTKMEGLPSGTPQSLPKEDDKTTKTIK 1318
Query: 235 ARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKAS 294
+ P K V P +K E+E + S+ S + ++P G +S
Sbjct: 1319 EQPQPPCTAKPDQVEPG-----------KEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSS 1367
Query: 295 EKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETP 354
+ I + G+ + P + + K +E S SS + + E
Sbjct: 1368 DGI----------SSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLES--- 1414
Query: 355 AAKALLQAKASGKTSQVGAASA-PAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSS 413
++L+A+AS + P + SP + P KT + EE+ + S
Sbjct: 1415 TVLSILEAQASTLADEKSEKKTQPHEVSPEQ---PKDQEKTQSLSETLEITISEEEIKES 1471
Query: 414 SEE------SDSEEEAPAQAKPSGKAPQV------RAASAPAKESPRKGAAPAPPRKTGP 461
EE DS+++ P+ K+ V R +ES +P P RK
Sbjct: 1472 QEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRT 1531
Query: 462 AAAQVQVGK-QEEDSRSSSEESDSDREALAAMNA--------------AQVKPLGKSPQ- 505
+ + ++EDS+ S EE D R+ + M+A Q+K + S +
Sbjct: 1532 SVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTES 1591
Query: 506 VKPASTMGMGPL--GKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTA 563
K T G G + GK + + W ++ + + +ES + E +
Sbjct: 1592 QKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQ 1651
Query: 564 VAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKA-----EKPMDNSESSEESSDSA 618
+ + G L+ T K + Q K E+P ES +S +
Sbjct: 1652 ESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDR 1711
Query: 619 DSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGS 678
E +++ A+ P + + ++++ S K + +A + P
Sbjct: 1712 SRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPT-- 1769
Query: 679 SPAVAGGTQRPAEDSSSSEESDSEEE 704
EDSS EE EEE
Sbjct: 1770 -----------IEDSSEEEELREEEE 1784
Score = 52.4 bits (124), Expect = 3e-06
Identities = 190/988 (19%), Positives = 330/988 (33%), Gaps = 152/988 (15%)
Query: 79 SDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138
S P ++ + +A AK+ P T + P++ K + KAE K +
Sbjct: 971 SQPPTSQGPPKSTGQAPPAPAKSIPVKKETKA-------PAAEKLEPKAEQAPTVKRTET 1023
Query: 139 MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADS 198
P K +L + P+K+ P T L + E + P G ++
Sbjct: 1024 EKKPPPIKDSKSLTA--EPQKAVLP---TKLEKSPKPESTCPLCKTELNIGSKDPPNFNT 1078
Query: 199 SSEDTSSSSDETDVEGKPSVKPAQV-------KASSVSTKESPARKAAPAPG-------K 244
+E + + P + Q ++S + RK PAP
Sbjct: 1079 CTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMP 1138
Query: 245 VGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAAS 304
V + K P K KK E+E ++ E E+ + + EKI
Sbjct: 1139 VPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKV------KETLSMEKI------- 1185
Query: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364
P T + + K A A Q K PEE EE SEE+ P LL+ K
Sbjct: 1186 -PPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKP----LLEEK- 1239
Query: 365 SGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP 424
P P K AK A + ++ S+ +EE+
Sbjct: 1240 ----------------------KPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLE 1277
Query: 425 AQAKP----SGKAPQVRAASAPA-----------KESPRKGAAPAPPRKTGPAAAQVQVG 469
+ P GK PQ + P+ K + P PP P QV+ G
Sbjct: 1278 GRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKP--DQVEPG 1335
Query: 470 KQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKV 529
K++ + ++ S ++ KSPQ + + G +P +
Sbjct: 1336 KEKTEKEDDKSDTSSSQQP-------------KSPQGLSDTGYSSDGISSSLGEIP--SL 1380
Query: 530 GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPP 589
P + ++D S S+ESS SS ++ E ++ +IL+A+ ++ +
Sbjct: 1381 IPTDEKDILKGLKKD--SFSQESSPSSPSDLAKL-----ESTVLSILEAQASTLADEKSE 1433
Query: 590 QKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 649
+K P V + K + ++S E+ + SEE + + K K + P +
Sbjct: 1434 KKTQPHEVSPEQPKDQEKTQSLSETLEITISEE-EIKESQEERKDTFKKDSQQDIPSSKD 1492
Query: 650 TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEE--------SDS 701
++ + P + +S + +SP V +R + SSSS+E S
Sbjct: 1493 HKEKSEFVDDITTRREPYDSVEESSESENSP-VPQRKRRTSVGSSSSDEYKQEDSQGSGE 1551
Query: 702 EEEKTGLAVTVGQAKSVGKG-----------LQVKAASVPVKGSLGQGTAPVLPGKTGPT 750
EE+ + A G ++ +++ K +G + GK
Sbjct: 1552 EEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRL 1611
Query: 751 VTQVKAEKQEDS--ESSEEESDSEEAAASPAQVKTSVKKTQAK-----ANPAAARAPSAK 803
+ ED+ S + D E SP K +++ R + +
Sbjct: 1612 TRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIE 1671
Query: 804 GTISAPGKVVTAAAQAK-----QRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAA 858
+ K ++Q K P + + G +S+ + T+
Sbjct: 1672 LNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSP 1731
Query: 859 QAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKE--SPRKGAAPTPP 916
+ + +EDS SS E + + A+ +P G L P E S +
Sbjct: 1732 TSVSSLDEDSDSSPSHKKGESKQQRKARHRPHG-------PLLPTIEDSSEEEELREEEE 1784
Query: 917 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 976
+ +Q SSS++S D + A + K P N SP A+
Sbjct: 1785 LLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTP----PSNLSPIEDASPTE 1840
Query: 977 QAQAASTPRKARASESTARSSSSESEDE 1004
+ + A+ + S + S S ES+ E
Sbjct: 1841 ELRQAAEMEELHRSSCSEYSPSIESDPE 1868
Score = 32.3 bits (72), Expect = 3.4
Identities = 61/288 (21%), Positives = 107/288 (37%), Gaps = 19/288 (6%)
Query: 380 ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSG--KAPQVR 437
+ P + A GK G ++ +A K + S+ SS + E Q +P G + P +R
Sbjct: 3483 DMPTRSRRKARVGKYGDSM--TEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIR 3540
Query: 438 AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 497
A E + +AP K G Q E DS + S + S
Sbjct: 3541 ARVDAKVEIIKHISAPEKTYKGGSLGCQT-----EADSDTQSPQYLSATSPPKDKKRPTP 3595
Query: 498 KPLGKSPQVKPASTMGMGPLGKGA-----GPVPPGKVGPATPSAQVGKWEEDSESSSEES 552
+G S ++ ST+ + P + P+ P G A SA V + + S +
Sbjct: 3596 LEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQK 3655
Query: 553 SDSSD-GEVPTA---VAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS 608
D +VP A A ++S+ + PT+ + P + K + M +S
Sbjct: 3656 VLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQY-TEGYTTKGSQTMTSS 3714
Query: 609 ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKV 656
+ ++ + + T Q+ + ++ +TNT A AK+
Sbjct: 3715 GAQKKVKRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKI 3762
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 119 bits (299), Expect = 2e-26
Identities = 255/1244 (20%), Positives = 420/1244 (33%), Gaps = 158/1244 (12%)
Query: 106 ASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSA 165
A + S D + + +A + G SMP G+ G +P S S
Sbjct: 881 AISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGE-------GSTPLTSMPDST 933
Query: 166 NTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKA 225
+ SE + P + A + +++E TS + T EG + V
Sbjct: 934 TPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTS-TPSEGTTPLTSTPVSH 992
Query: 226 SSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPA 285
+ V+ E+ P T P A+ P + + EGS P
Sbjct: 993 TLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMP---TSTPSEGSTPLTRMPV 1049
Query: 286 GTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEE 345
T + V +SE ++ TP +TP + A +S T A + + SE
Sbjct: 1050 ST-TMVASSE--------TSTLSTTPADTSTPVTT-YSQASSSSTTADGTSMPTSTYSEG 1099
Query: 346 SSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAP----------APPGKTG 395
S+ + + ++ ++AS ++ S P S ++P +PP +
Sbjct: 1100 STPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGT 1159
Query: 396 PAVAKAQAGKR----EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGA 451
+A E + S+ DS+ + + S P S P +P + +
Sbjct: 1160 TPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTS-TPGERS 1218
Query: 452 APA---PPRKTGPAAAQVQVGKQEEDSRS-----SSEESDSDREALAAMNAAQVKPLGKS 503
P P R T A+++ S S+E S S A G +
Sbjct: 1219 TPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGST 1278
Query: 504 --PQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVP 561
+ ++T+ P P GP S +V +E +S +S S+G P
Sbjct: 1279 LLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTP 1338
Query: 562 TAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSE 621
P + + A+ + + P+DNS S+++ S
Sbjct: 1339 LTSIPVNTTLVASS--------------------AISILSTTPVDNSTPVTTSTEACSSP 1378
Query: 622 EAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPA 681
+ + P+ + P T S++ + + GT ++ A SSP
Sbjct: 1379 TTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPT 1438
Query: 682 VAGG----TQRPAEDSS-------SSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVP 730
A G T P+E + S+ + E T V V V ++ P
Sbjct: 1439 TAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTP 1498
Query: 731 VKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKK-TQ 789
+G+ A P + +T + S ++ S+ + +PA T V +Q
Sbjct: 1499 AEGT---SIAISTPSEGSTALTSIPV-----STTTVASSEINSLSTTPAVTSTPVTTYSQ 1550
Query: 790 AKANPAAARAPSAKGTISAPGK------------VVTAAAQAKQRSP--SKVKPPVRNPQ 835
A ++P A S + + + G VV++ A +P SK +
Sbjct: 1551 ASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEA 1610
Query: 836 NSTVLARGPA---SVPSVGKAVATAAQAQTGP---EEDSGSSEEESDSEEEAETLAQVKP 889
+S+ A G + S PS G + T+ T P E S S DS T +V
Sbjct: 1611 SSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSS 1670
Query: 890 S----------------GKT--HQIRAALAPAKESPRKGAAPTP-----PGKTGPSAAQA 926
S G+T I P S + TP P T A +
Sbjct: 1671 SPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSS 1730
Query: 927 GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 986
+ S + S+G P +TS V P++ + + A P T + +T +
Sbjct: 1731 PTTSEGTSMPNSTPSEGTTP--LTSIPVSTTPVLSSEASTLSATPIDT---STPVTTSTE 1785
Query: 987 ARASESTARSSS--SESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSK 1044
A +S +TA +S + + E + P T TP T V + P S + +S
Sbjct: 1786 ATSSPTTAEGTSIPTSTLSEGMTPLTS--TPVSHTLVANSEASTLSTTPVDSNSPVVTST 1843
Query: 1045 ESSRISDGKKQEGPATQVDSAVGTLPATSPQS-TSVQAKGTNKL-RKPKLPEVQQATKAP 1102
S + AT S T + P S T+V + TN L P + T A
Sbjct: 1844 AVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQ 1903
Query: 1103 -ESSDDSEDSSDSSSGSEEDGEGP---------QGAKSAHTLVGPTPSRTETLVEETAAE 1152
SS + D S + + +G P A S + T + T T V T ++
Sbjct: 1904 VSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPV-TTYSQ 1962
Query: 1153 SSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKP 1212
+S A S+ + + G TP S T + S S ST P
Sbjct: 1963 ASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLST-----TPVDTSTPAT 2017
Query: 1213 QQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQS 1256
G SP T G + +TP + P AG P ++TL + S
Sbjct: 2018 TSTEGSSSPTTAGGTSIQTSTPSERTTPL--AGMPVSTTLVVSS 2059
Score = 109 bits (273), Expect = 2e-23
Identities = 255/1226 (20%), Positives = 412/1226 (33%), Gaps = 164/1226 (13%)
Query: 67 EDAALQAKKTRVSDPISTS-ESSEEEEEAEAETAK-ATPRLASTN-SSVLGADLPSSMKE 123
E + L S P++TS E+S AE + + +TP ST +S+L + LP + E
Sbjct: 2708 EASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSE 2767
Query: 124 KAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEE-GSVPAF 182
+ T T P T T A+ SP + S T+ SET S+P
Sbjct: 2768 ASTVST-----TAVDTSIPVTTSTEAS----SSPTTAEVTSMPTSTPSETSTPLTSMPVN 2818
Query: 183 G---AAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAA 239
A+++ G +S D+S+ T+S T P+ V S +++ S +
Sbjct: 2819 HTPVASSEAGTLSTTPVDTSTPVTTS----TKASSSPTTAEGIVVPISTASEGSTLLTSI 2874
Query: 240 PAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEA-----PAGTRSQVKAS 294
P TP A + +S EGS S A P T S+V S
Sbjct: 2875 PV-----STTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEV--S 2927
Query: 295 EKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEE-SSDSEEET 353
+ + ++ P G+ + P V + +A +E +S S+ E T
Sbjct: 2928 TPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRT 2987
Query: 354 PAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSS 413
P + + ++ P S + P + P +A SS
Sbjct: 2988 PL-------------TSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEA--------SS 3026
Query: 414 SEESDSEEEAPAQAKPSGKAP--QVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQ 471
S + P G P + ++ P + P P +V
Sbjct: 3027 SPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSS 3086
Query: 472 EEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPA-STMGMGPLGKGAGPVPPGKVG 530
+ +S + E + P+ +P A ST+ P+
Sbjct: 3087 PTPAEGTSMPISTYSEGSTPLTGV---PVSTTPVTSSAISTLSTTPVDTST--------- 3134
Query: 531 PATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQE----KSLGNILQAKP------ 580
P T S + SE +S +S S+G P P S + L A P
Sbjct: 3135 PVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTP 3194
Query: 581 ---------------TSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPA 625
TS P P + P+ + P+ +SE+S S+ DS
Sbjct: 3195 VTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLT 3254
Query: 626 AMTAAQAKPAL--------KIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT---- 673
T A + P P + P + ++ VA T + A T+T
Sbjct: 3255 TSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTT 3314
Query: 674 -SPAGSSPAVAGGTQRPAEDSS-----------------SSEES--DSEEEKTGLAVTVG 713
S A SSP +A GT P S SSE S + T VT
Sbjct: 3315 YSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTS 3374
Query: 714 QAKSVGKGLQVKAASVPVKGSLGQGTAPV--LPGKTGPTV-TQVKAEKQEDSESSEEESD 770
S+ + S+P S +GT P+ +P T P V ++V +S+ +
Sbjct: 3375 TEASLSP-TTAEGTSIPT-SSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTT 3432
Query: 771 SEEAAASP--AQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 828
S EA++SP A+ + T ++ + + P + +++ + +P
Sbjct: 3433 STEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTS 3492
Query: 829 PPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGP---EEDSGSSEEESDSEEEAETLA 885
P + + + P S G T T P E S S DS + +
Sbjct: 3493 SPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSS 3552
Query: 886 QVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEA 945
Q S T Q+ +P +G++ S+ + S S+ D
Sbjct: 3553 QASSSPATLQVTTM---RMSTPSEGSSSLTTMLL--SSTYVTSSEASTPSTPSVDRSTPV 3607
Query: 946 PAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDED 1005
+ S PP + P +P+ +TP ST SE+ S+
Sbjct: 3608 TTSTQSNSTPTPPEVITLPMSTPS-EVSTPLTIMPVST-TSVTISEAGTASTLPVDTSTP 3665
Query: 1006 VIPATQCLTPGIRTNVVTMPT------AHPRIAPKASMAGASSSKESSRISDGKKQEGPA 1059
VI +TQ + + TMP + P S +SS+ S+ + P
Sbjct: 3666 VITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPV 3725
Query: 1060 TQVDSAVGTLPATSPQSTSV-QAKGTNKLRKPKLPEVQQATKAPESSDDSEDS---SDSS 1115
T A+ + + SV + L L T+ PESS S S S S
Sbjct: 3726 TTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSM 3785
Query: 1116 SGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLT 1175
+ + E P + T+ T S TL+ T S V++PS++ S TP
Sbjct: 3786 TTASEGSSSPTTLEGTTTMPMSTTSERSTLL--TTVLISPISVMSPSEA--STLSTP--- 3838
Query: 1176 PANSQASKATPKLDSSPSVSSTLAAK 1201
+TP L S+ + S ++ A+
Sbjct: 3839 ----PGDTSTPLLTSTKAGSFSIPAE 3860
Score = 103 bits (256), Expect = 2e-21
Identities = 264/1361 (19%), Positives = 457/1361 (33%), Gaps = 145/1361 (10%)
Query: 81 PISTSESSEEEEEAEAETAKATPR---LASTNSSVLGADLPSSMKEKAKAETEKAGKTGN 137
P ST ++S + +TP ++ST + V A LPS +A T K
Sbjct: 130 PSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSF-----EAYTSLTYKVDM 184
Query: 138 SMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQAD 197
S P L + S +TT+ T EGS P A V++ +A
Sbjct: 185 STP----------LTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAI 234
Query: 198 SSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP---APGKVGDVTPQVKG 254
+ S + + S P + S+S +P+ + P P V V
Sbjct: 235 TLLTTPVEISTPVTISAQASSSPTTAEGPSLS-NSAPSGGSTPLTRMPLSVMLVVSSEAS 293
Query: 255 GALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG 314
P S + + E T + + S + A++ P +
Sbjct: 294 TLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMST 353
Query: 315 ATPAPPGKAGAVASQTKAGKPEEDSESSS------EESSDSEEETPAAKALLQAKASGKT 368
+ P + V + T+ +E++S E S P + L+ + + T
Sbjct: 354 LSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTT 413
Query: 369 SQV------------GAASAP--------AKESPRKGAAP--APPGKTGPAVAKAQAGKR 406
S + A+S+P A +P +G+ P + P T P +
Sbjct: 414 STIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVAS------- 466
Query: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV 466
E S S+ DS+ + + S P S P +P +G+ P T + + +
Sbjct: 467 SEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPT-STPSEGSTPL----TSMSVSTM 521
Query: 467 QVGKQEEDSRSSSE-ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP 525
V E + S++ ++ + + +++ P G S P ST G PV
Sbjct: 522 PVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTS---IPTSTPSEGSTPLTNMPVS 578
Query: 526 PGKV--GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSS 583
V A+ ++ ++S E+S SS T++ + G + + S+
Sbjct: 579 TRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVST 638
Query: 584 PAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIP--QT 641
+ + V + P+ S + SS +A+ P + + P +P T
Sbjct: 639 TLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTT 698
Query: 642 KACPKKTNTTASAKV---APVRVGTQAPRKAGTA--------TSPAGSSPAVAGGTQRPA 690
+ +T ++ V PV T+A TA T GS+P + +
Sbjct: 699 LVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTL 758
Query: 691 EDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPT 750
SS + + T +T S + S+P+ S +P+L T
Sbjct: 759 LTSSEASTLSTTPLDTSTHITTSTEASCSP-TTTEGTSMPI--STPSEGSPLL---TSIP 812
Query: 751 VTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPG 810
V+ E S S DS + +V +S + + P + + S P
Sbjct: 813 VSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPV 872
Query: 811 K---VVTAAAQAKQRSPSKVKPPVRN---PQNSTVLARG---PASVPSVGKAVATAAQAQ 861
V T+A +P PV N ++S + G P S P G T+
Sbjct: 873 STTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDS 932
Query: 862 TGPEEDSGSSEEESDSEEEAETLAQVKPSGK-THQIRAALAPAKESPRKGAAPTPPGKTG 920
T P SSE + S +T V S + T A + + TP T
Sbjct: 933 TTPVV---SSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTP 989
Query: 921 PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPA--ATPAQA 978
S + S S+ DS+ TS + PP + + P+ +TP
Sbjct: 990 VSHTLVANSEASTLSTTPVDSN---TPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTR 1046
Query: 979 QAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTA--HPRIAPKAS 1036
ST A +SE++ S++ V +Q + + +MPT+ P S
Sbjct: 1047 MPVSTTMVA-SSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTS 1105
Query: 1037 MAGASS---SKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKP--- 1090
+ ++ S E+S +S T VD+++ +T S+ A+GT+ P
Sbjct: 1106 VPVSTRLVVSSEASTLS--------TTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSE 1157
Query: 1091 ------KLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTET 1144
+P + E++ S DS + E +A PT + E
Sbjct: 1158 GTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGER 1217
Query: 1145 LVEETAAESSEDDVVAPSQSLLS----GYMTPGLTPANSQASKATPKLDSSP----SVSS 1196
T+ V + S LS TP T A + +S T + S P S S
Sbjct: 1218 STPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGS 1277
Query: 1197 TLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQS 1256
TL P+ + + +P + S P +G P ++ ++
Sbjct: 1278 TLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRT 1337
Query: 1257 NITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQ 1316
+T P+N V +S + +L+ V +T+ S + +
Sbjct: 1338 PLTSI------PVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNP 1391
Query: 1317 PAARTPRSK---KKKKLGAGEGGEASVSPEKTSTTSKGKAK 1354
TP + + + E S +P TST A+
Sbjct: 1392 SEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAE 1432
Score = 102 bits (254), Expect = 3e-21
Identities = 243/1288 (18%), Positives = 426/1288 (33%), Gaps = 148/1288 (11%)
Query: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142
S S+ + +EA T TP ST ++ A SS + +G S P
Sbjct: 220 SMPASTMKVASSEAITLLTTPVEISTPVTI-SAQASSSPTTAEGPSLSNSAPSGGSTPLT 278
Query: 143 ATGKTVANLLSGKSPRKSAEPSAN-------------------TTLVSETEEEGSVPAFG 183
+V ++S ++ S P+A T++ + T EGS P
Sbjct: 279 RMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTS 338
Query: 184 AAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPG 243
A V+ + + S +S +PS P +A+S+ T
Sbjct: 339 TPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNM 398
Query: 244 KVGDV---TPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300
V + + + + P SE+S + +E+ + A T + + S + +
Sbjct: 399 PVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIA-TSTPSEGSTPLTSM 457
Query: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSE-SSSEESSDSEEETP----- 354
++ P + + P V + T+A +E +S S+ SE TP
Sbjct: 458 PVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMS 517
Query: 355 -AAKALLQAKASG-KTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGK------- 405
+ + ++AS T+ V ++ S ++ P G + P ++
Sbjct: 518 VSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPV 577
Query: 406 ------REEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKT 459
E S +S+ +DS ++ S + S P +G +
Sbjct: 578 STRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVS 637
Query: 460 GPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPL-- 517
A + S+ + EA ++ A+ + S + ++ + P+
Sbjct: 638 TTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNT 697
Query: 518 -------GKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEK 570
P P T S + ++ +S +S S+G P P +
Sbjct: 698 TLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSK- 756
Query: 571 SLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAP------ 624
+L + S+ + P + + +A +E + S SE +P
Sbjct: 757 ---TLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGT-SMPISTPSEGSPLLTSIP 812
Query: 625 ---AAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPA 681
+T+ +A P P T+T S+ P GT P T+T G +P
Sbjct: 813 VSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAE-GTSMP----TSTYSEGRTPL 867
Query: 682 VAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP 741
+ +S+ + T VT ++ + S+P + G+G+ P
Sbjct: 868 TSMPVSTTLVATSAISTLSTTPVDTSTPVT-NSTEARSSPTTSEGTSMPT-STPGEGSTP 925
Query: 742 V--LPGKTGPTV-TQVKAEKQEDSESSEEESDSEEAAASPAQVK-TSVKKTQAKANPAAA 797
+ +P T P V ++ + ++S + S EA +SP + TS+ +
Sbjct: 926 LTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPL 985
Query: 798 RAPSAKGTISAPGKVVT-AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVAT 856
+ T+ A + T + +P +P + P S PS G T
Sbjct: 986 TSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLT 1045
Query: 857 AAQAQT---GPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAP 913
T E S S +D+ T +Q S T A + +
Sbjct: 1046 RMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTT-----ADGTSMPTSTYSEGS 1100
Query: 914 TPPGKTGPSAAQAGKQDDSGSSSEESD------SDGEAPAAVTSAQVIKPPLIFVDPNRS 967
TP S + S S+ D + EA ++ T+A+ P S
Sbjct: 1101 TPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIP-------TS 1153
Query: 968 PAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTA 1027
P TP + ST +SE+ S++ V +T+ +P V +MPT+
Sbjct: 1154 PPSEGTTPLASMPVSTTLVV-SSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTS 1212
Query: 1028 HP--RIAPKASMA---GASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQS---TSV 1079
P R P SM +S E+S +S + + P T+ + TS
Sbjct: 1213 TPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTST 1272
Query: 1080 QAKGTNKLRKPKL-------PEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQ------ 1126
++G+ L + PE P + +S+ S S EG
Sbjct: 1273 TSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTY 1332
Query: 1127 ----------------GAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYM 1170
A SA +++ TP T V T+ E+ + S+ +
Sbjct: 1333 SEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPV-TTSTEACSSPTTSEGTSMPNSNP 1391
Query: 1171 TPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAK----PQQAAGMLSPKTGGK 1226
+ G TP S TP + S S S G A+ P A G+ P +
Sbjct: 1392 SEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPS 1451
Query: 1227 EAASGTTPQKS-RKPKKGAGNPQASTLA 1253
E G TP KS N +ASTL+
Sbjct: 1452 E---GKTPLKSIPVSNTPVANSEASTLS 1476
Score = 102 bits (254), Expect = 3e-21
Identities = 219/1178 (18%), Positives = 398/1178 (33%), Gaps = 125/1178 (10%)
Query: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142
ST ++ E + TA+AT L ST S G+ ++M T +++P
Sbjct: 362 STLVTTSTEPSSLPTTAEATSMLTSTLSE--GSTPLTNMPVSTILVASSEASTTSTIP-- 417
Query: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQAD----- 197
KT S S S + +T++ + T EGS P V++ +A
Sbjct: 418 VDSKTFVTTASEAS--SSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTT 475
Query: 198 --------SSSEDTSSSSDETDVEGKPSVKPAQ----VKASSVSTKESPARKAAPAPGKV 245
++S + SSS +V P+ P++ + + SVST + +A+
Sbjct: 476 PVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTP 535
Query: 246 GDVTPQVKGGALPPAKRAKKPEEES---ESSEEGSESEEEAPAGTR----------SQVK 292
D + V + + + PE S + EGS P TR S
Sbjct: 536 VDTSTPVTTSS-EASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTP 594
Query: 293 ASEKILQVRAASAPAKGTPGKGA---TPAPPGKAGAVASQTKAGKPEEDSESSSEESSDS 349
A ++ A + T +G T + + S + + SE+S+ ++
Sbjct: 595 ADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPV 654
Query: 350 EEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREED 409
+ TP + +A+ ++ S P + +G+ P + + E
Sbjct: 655 DSNTPVTTS---TEATSSSTTAEGTSMPT-STYTEGSTPLTSMPVNTTLVAS-----SEA 705
Query: 410 SQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP---APPRKTGPAAAQV 466
S S+ D+ + S AS P +P +G+ P P KT +++
Sbjct: 706 STLSTTPVDTSTPVTTSTEASSSPTTADGASMPT-STPSEGSTPLTSMPVSKTLLTSSEA 764
Query: 467 QVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKP-------ASTMGMGPLGK 519
S+ + ++ P+ + P + T P
Sbjct: 765 STLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEAS 824
Query: 520 GAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAK 579
P P T S +V +E +S +S S+G P P + +
Sbjct: 825 TLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAIST 884
Query: 580 PTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIP 639
+++P V P+ NS + S +++ P + + P +P
Sbjct: 885 LSTTP--------------VDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMP 930
Query: 640 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEES 699
+ P ++ + PV T T ++ A SSP A GT P S
Sbjct: 931 DS-TTPVVSSEARTLSATPVDTSTPV-----TTSTEATSSPTTAEGTSIPTSTPSEGTTP 984
Query: 700 DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAE-- 757
+ + V +A ++ V + + + P G + PT T +
Sbjct: 985 LTSTPVSHTLVANSEASTLST-TPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTP 1043
Query: 758 --KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTA 815
+ S + S++ + +PA T V + A++ + +A GT S P +
Sbjct: 1044 LTRMPVSTTMVASSETSTLSTTPADTSTPV----TTYSQASSSSTTADGT-SMPTSTYSE 1098
Query: 816 AAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEES 875
+ P + V + ++ S+P V T+ +A + P G+S S
Sbjct: 1099 GSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIP-----VTTSTEASSSPTTAEGTSIPTS 1153
Query: 876 DSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGS- 934
E LA + + L + E+ P ++ +A +
Sbjct: 1154 PPSEGTTPLASM-------PVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEV 1206
Query: 935 SSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ-AQAASTPRKARASEST 993
+S + + GE +TS V P+ + + P T +A T +E T
Sbjct: 1207 TSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGT 1266
Query: 994 ARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAG--ASSSKESSRISD 1051
+ +S+ SE ++ + + T +VT P A + G +S++ SS +
Sbjct: 1267 SLPTSTTSEGSTLLTSIP-----VSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTP 1321
Query: 1052 GKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDS 1111
+ P + L + +T V + + L + T + E+ S
Sbjct: 1322 AEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTS 1381
Query: 1112 SDSSSGSEEDGEG------------PQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVV 1159
+S + EG P + A TL TP T T T+AE++
Sbjct: 1382 EGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTL-SATPVDTST-PGTTSAEATSSPTT 1439
Query: 1160 APSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSST 1197
A S+ + + G TP S TP +S S ST
Sbjct: 1440 AEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLST 1477
Score = 96.7 bits (239), Expect = 1e-19
Identities = 238/1284 (18%), Positives = 426/1284 (33%), Gaps = 176/1284 (13%)
Query: 79 SDPISTSE--SSEEEEEAEAETAKATP-----RLASTNSSVLGADLPSSMKEKAKAETEK 131
S P+ST+ SSE + +TP +++S+ ++ G+ +P+S + +
Sbjct: 1871 SIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTS 1930
Query: 132 AGKTGNSMPHPATGKTVANLLSGKSP-----RKSAEPSA--NTTLVSETEEEGSVPAFGA 184
+ ++ L ++P + S+ P+ T++ + EGS P
Sbjct: 1931 IPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSM 1990
Query: 185 AAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGK 244
+V + +A + S +S + S P +S+ T +P+ + P G
Sbjct: 1991 PLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTS-TPSERTTPLAGM 2049
Query: 245 VGDVTPQV--KGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRA 302
T V +G L K + + + S + E + + + S + +
Sbjct: 2050 PVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPL 2109
Query: 303 ASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSD-SEEETPAAKALLQ 361
++ P + P V + T+ +E +S ++S S+ TP L
Sbjct: 2110 STTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTP-----LT 2164
Query: 362 AKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEE 421
+ T +A + +P + P +A++ + S + SE
Sbjct: 2165 SMPVSTTVVASSAISTLSTTPVDTSTPVTNS------TEARSSPTTSEGTSMPTSTPSEG 2218
Query: 422 EAPAQAKPSGKAPQVRA-----------ASAPAKESPRKGAAPAPPRKTGPAAAQVQVGK 470
P + P P V + S P S ++P T + + G
Sbjct: 2219 STPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGT 2278
Query: 471 --------------QEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGP 516
E S S+ DS+ + A+ P + + P ST G
Sbjct: 2279 TPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSM-PTSTSSEGN 2337
Query: 517 LGKGAGPV----------------PPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEV 560
PV P P T +Q G ++ +S +S S+G
Sbjct: 2338 TPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGST 2397
Query: 561 PTAVAPAQE--------------------------KSLGNILQAKPTSSPAKGPPQKAGP 594
P P ++ + A+ TS P P + P
Sbjct: 2398 PLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTP 2457
Query: 595 VAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASA 654
+A + P+ +SE+ S+ D+ T A + P + P T + S
Sbjct: 2458 LASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTA--EDIVVPISTASEGST 2515
Query: 655 KVAPVRVGTQ---APRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVT 711
+ + V T +P + +T+P S+ V +S+E S S G ++
Sbjct: 2516 LLTSIPVSTTPVASPEASTLSTTPVDSNSPVV----------TSTEISSSATSAEGTSMP 2565
Query: 712 VGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDS 771
L+ S S T P T VT E S S D+
Sbjct: 2566 TSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTT----STETSSSPTTAKDT 2621
Query: 772 EEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK--- 828
++P++V TS+ P A+ S T + + + SP+ +
Sbjct: 2622 SMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSS 2681
Query: 829 PPVRNP-----------QNSTVLARGPASVPS-----VGKAVATAAQAQTGPEEDSGSSE 872
P P ++T+LA AS S V T+A+A + P G+S
Sbjct: 2682 MPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSM 2741
Query: 873 EESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDS 932
S + + L + S + A + A + P T A+ + +
Sbjct: 2742 RISTPSDGSTPLTSILVS----TLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEV 2797
Query: 933 GSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASES 992
S + S+ P +TS V P+ + P T + +T KA +S +
Sbjct: 2798 TSMPTSTPSETSTP--LTSMPVNHTPVASSEAGTLSTTPVDT---STPVTTSTKASSSPT 2852
Query: 993 TARS----SSSESEDEDVIPATQCLTPGIRTNVVTMPTAHP---RIAPKASMAGASS--- 1042
TA S+ SE ++ + T + ++ + + P I S G+SS
Sbjct: 2853 TAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTT 2912
Query: 1043 -SKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSV-------QAKGTNKLRKPKLPE 1094
S IS + P T + V T+P +++++ + T P
Sbjct: 2913 AEGTSMPISTPSEVSTPLTSI--LVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPT 2970
Query: 1095 VQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESS 1154
+ T P S+ + +S P + A TL TP+ T T V T+ E+S
Sbjct: 2971 TAEGTSMPISTPGERRTPLTSMSV---STMPVASSEASTL-SRTPADTSTPV-TTSTEAS 3025
Query: 1155 EDDVVAPSQSLLSGYMTPGLTPANSQASKATP-KLDSSPSVSSTLAAKDDP---DGKQEA 1210
A + + G TP S TP + + ++S+T + P + +
Sbjct: 3026 SSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSS 3085
Query: 1211 KPQQAAGMLSPKTGGKEAASGTTP 1234
P A G P + E G+TP
Sbjct: 3086 SPTPAEGTSMPISTYSE---GSTP 3106
Score = 93.2 bits (230), Expect = 2e-18
Identities = 255/1276 (19%), Positives = 419/1276 (32%), Gaps = 157/1276 (12%)
Query: 65 AEEDAALQAKKTRVSDPISTS-ESSEEEEEAEAETAK-ATPRLASTN-SSVLGADLPSSM 121
+ E + L S P++TS E S AE + +TP ST +S+L + +P +
Sbjct: 2883 SSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAG 2942
Query: 122 KEKAKAETEKAGK------TGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEE 175
E + T + + P T + + +S R++ S + + +
Sbjct: 2943 SEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASS 3002
Query: 176 EGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSD---ETDVEGKPSVKPAQVKASSVSTKE 232
E S + A V+ SSS T+ + T EG + V + V+ E
Sbjct: 3003 EASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPE 3062
Query: 233 SPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVK 292
+ P VT + PA+ P + EGS P T
Sbjct: 3063 ASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMP---ISTYSEGSTPLTGVPVSTTPVTS 3119
Query: 293 ASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSES----------- 341
++ L TP +T A + + P E S
Sbjct: 3120 SAISTLSTTPVDT---STPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLV 3176
Query: 342 -SSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAK 400
SSE+S+ S + + + + ++ S P +P +G P T V+
Sbjct: 3177 VSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTS-TPSEGMTPL----TSVPVSN 3231
Query: 401 AQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP--APPRK 458
E S S+ DS + S P S P +P +G+ P + P
Sbjct: 3232 TPVASSEA-SILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTS-TPSEGSTPLTSMPVS 3289
Query: 459 TGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLG 518
T A+ E S S+ +D+ A+ P+ + P ST G
Sbjct: 3290 TTTVASS-------ETSTLSTTPADTSTPVTTYSQASSSPPIADGTSM-PTSTYSEG--- 3338
Query: 519 KGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQA 578
+TP + SS + ++ + T V + E SL A
Sbjct: 3339 -------------STPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTT-A 3384
Query: 579 KPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL-- 636
+ TS P P + P+A + P+ +SE + S+ DS T A + P +
Sbjct: 3385 EGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAE 3444
Query: 637 --KIPQTKAC---------PKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGG 685
+P + P T AS++ + + T +SP SSP A
Sbjct: 3445 GTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEV 3504
Query: 686 TQRPAE--------------------DSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVK 725
T P S +S S + + + QA S LQV
Sbjct: 3505 TSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVT 3564
Query: 726 AA--SVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKT 783
S P +GS T + + + D + S + +P +V T
Sbjct: 3565 TMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVIT 3624
Query: 784 SVKKTQAKANPAAARAP--------SAKGTISA-PGKVVTAAAQAKQRSPSKVKP----- 829
T ++ + P S GT S P T + Q S S V P
Sbjct: 3625 LPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTM 3684
Query: 830 PVRNP-QNSTVLARGPASVPSVGKA---------VATAAQAQTGPEEDSGSSEEESDSEE 879
P+ P + ST L P S V + V T+ T E S S+ +S +
Sbjct: 3685 PIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMS 3744
Query: 880 EAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEES 939
+ + ++ G T I + P P P T S A + S ++ E +
Sbjct: 3745 VSMPM-EISTLGTT--ILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGT 3801
Query: 940 DSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASES-TARSSS 998
+ P + TS + + + P +P++A STP ++ T+ +
Sbjct: 3802 TT---MPMSTTSERSTLLTTVLISPIS-----VMSPSEASTLSTPPGDTSTPLLTSTKAG 3853
Query: 999 SESEDEDVIPATQCLTPGIRTNVVTM--PTAHPRIAPKASMAGASSSKESSRISDGKKQE 1056
S S +V +T T + T+ T P P AS+A S+ +
Sbjct: 3854 SFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFT------ 3907
Query: 1057 GPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSS 1116
P+T S T+P + S SV +G+ +P + + + + +
Sbjct: 3908 -PSTDTASTP-TIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPV 3965
Query: 1117 GSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDV-VAPSQSLLSGYMTPGLT 1175
+ + P + S+ T T T TAA + + APS TP T
Sbjct: 3966 ITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPS--------TPRTT 4017
Query: 1176 PANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQ 1235
S +T S+P S+++ + + ++P P T A S T P
Sbjct: 4018 SRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPT-FPPAHSSTPPT 4076
Query: 1236 KSRKPKKGAGNPQAST 1251
S NP+A T
Sbjct: 4077 TS--ASSTTVNPEAVT 4090
Score = 82.4 bits (202), Expect = 3e-15
Identities = 206/1059 (19%), Positives = 372/1059 (35%), Gaps = 137/1059 (12%)
Query: 65 AEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLG--ADLPSSMK 122
+ ED+ L A S P++TS E + TA+ T ST S + +P S
Sbjct: 3178 SSEDSTLSATPVDTSTPVTTS-----TEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNT 3232
Query: 123 EKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSA-NTTLVSETEEEGSVPA 181
A +E T P T T A+ S+ P+A T++ + T EGS P
Sbjct: 3233 PVASSEASILSTTPVDSNTPLTTSTEAS---------SSPPTAEGTSMPTSTPSEGSTPL 3283
Query: 182 FGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPA 241
V++ + + S + +S + S P +S+ T + + + P
Sbjct: 3284 TSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPT-STYSEGSTPL 3342
Query: 242 PGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVR 301
TP V A S+ + + P T ++ S +
Sbjct: 3343 TNMSFSTTPVVSSEA---------------STLSTTPVDTSTPVTTSTEASLSPTTAE-- 3385
Query: 302 AASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQ 361
S P +P +G TP +AS + P SE ++ ++ + T +
Sbjct: 3386 GTSIPT-SSPSEGTTP--------LASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTS--- 3433
Query: 362 AKASGKTSQVGAASAPAKESPRKGAAPAP--PGKTGPAVAKAQAGKREEDSQSSSEESDS 419
+AS + S P + +G+ P P T P + E S S+ D+
Sbjct: 3434 TEASSSPTIAEGTSLPT-STTSEGSTPLSIMPLSTTPVAS-------SEASTLSTTPVDT 3485
Query: 420 EEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAP--PRKTGPAAAQVQVGKQEEDSRS 477
+ P+ +P ++ + +G+ P P T P A+ E S
Sbjct: 3486 STPV-TTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVAS-------SEASTL 3537
Query: 478 SSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQ 537
S+ DS+ ++ A+ SP +TM M +G+ + T
Sbjct: 3538 STTPVDSNTFVTSSSQAS------SSPATLQVTTMRMSTPSEGSSSL--------TTMLL 3583
Query: 538 VGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAV 597
+ SE+S+ S+ S D P + +S + + P P + + P+ +
Sbjct: 3584 SSTYVTSSEAST-PSTPSVDRSTPVTTS---TQSNSTPTPPEVITLPMSTPSEVSTPLTI 3639
Query: 598 QVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVA 657
+ + SE+ S+ D+ + +T+ Q + P+ P T + S +
Sbjct: 3640 MPVSTTSVTISEAGTASTLPVDT--STPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLT 3697
Query: 658 PVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKS 717
+ V T + +T S+P+V T P S+ + S + + T ++V++ S
Sbjct: 3698 TMPVSTTRVTSSEGSTL---STPSVV--TSTPVTTSTEAISSSATLDSTTMSVSMPMEIS 3752
Query: 718 VGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAAS 777
G + ++ PV + + P +P T + + SS +
Sbjct: 3753 T-LGTTILVSTTPVT-RFPESSTPSIPS----VYTSMSMTTASEGSSSPTTLEGTTTMPM 3806
Query: 778 PAQVKTSVKKTQAKANPAAARAPSAKGTISA-PGKVVTAAAQAKQRSPSKVKPPVRNPQN 836
+ S T +P + +PS T+S PG T + + + V +
Sbjct: 3807 STTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRI 3866
Query: 837 STVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQI 896
S R S P V+T T P G+S + + + T + T I
Sbjct: 3867 SITSER---STPLTTLLVST-----TLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTI 3918
Query: 897 RAALAPAKESPRKGAAP--------TP---------PGKTG----PSAAQAGKQDDSGSS 935
A + +G+ P TP P TG P S SS
Sbjct: 3919 PVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSS 3978
Query: 936 SEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTAR 995
S + S T A PL +V + +P+ P T ++ +T ++ ST
Sbjct: 3979 SSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTT---SRGCTTSASTLSATSTPH 4035
Query: 996 SSSSESEDEDVIPATQCLTPGIRTNVV---TMPTAHPRIAPKASMAGASSSKESSRISDG 1052
+S+S + V P+++ P T+ T P AH P S + + + E+ ++
Sbjct: 4036 TSTSVT-TRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEA--VTTM 4092
Query: 1053 KKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPK 1091
+ P+T+ S P +T++++ T+ P+
Sbjct: 4093 TTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPR 4131
Score = 81.6 bits (200), Expect = 5e-15
Identities = 224/1092 (20%), Positives = 364/1092 (33%), Gaps = 158/1092 (14%)
Query: 79 SDPIST-SESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGN 137
S PIST SE S T T ST S+ D + + +A + G
Sbjct: 3094 SMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTT-PVDTSTPVTTSTEAHSSPTTSEGT 3152
Query: 138 SMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQAD 197
SMP + G +P S + SE + P + P S
Sbjct: 3153 SMPTSTPSE-------GSTPLTYMPVSTMLVVSSEDSTLSATPV--DTSTPVTTSTEATS 3203
Query: 198 SSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGAL 257
S++ + +S T EG + V + V++ E+ P T +
Sbjct: 3204 STTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSP 3263
Query: 258 PPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATP 317
P A+ P + + EGS P T + + L A T A+
Sbjct: 3264 PTAEGTSMP---TSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASS 3320
Query: 318 APPGKAGA-------------VASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364
+PP G + + + + P SE+S+ ++ + TP + +A
Sbjct: 3321 SPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTST-EASL 3379
Query: 365 SGKTSQVGAASAPAKESPRKGAAP--APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE 422
S T++ S P SP +G P + P T P V+ E + S+ DS
Sbjct: 3380 SPTTAE--GTSIPTS-SPSEGTTPLASMPVSTTPVVSS-------EVNTLSTTPVDSNTL 3429
Query: 423 APAQAKPSGKAPQVRAASAPAKESPRKGAAPAP--PRKTGPAAAQVQVGKQEEDSRSSSE 480
+ S S P + +G+ P P T P A+ E S S+
Sbjct: 3430 VTTSTEASSSPTIAEGTSLPTSTTS-EGSTPLSIMPLSTTPVASS-------EASTLSTT 3481
Query: 481 ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP--PGKVGPATPS--A 536
D+ + P SP ++M G+G+ P+ P P S +
Sbjct: 3482 PVDTSTPVTTS------SPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEAS 3535
Query: 537 QVGKWEEDSE----SSSEESSDSSDGEVPTA--VAPAQ-EKSLGNILQAKP--TSSPAKG 587
+ DS SSS+ SS + +V T P++ SL +L + TSS A
Sbjct: 3536 TLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEAST 3595
Query: 588 PP----QKAGPVAVQVKAEKP--------MDNSESSEESSDSADSEEAPAAMTAAQAKPA 635
P ++ PV ++ + S SE S+ + ++T ++A A
Sbjct: 3596 PSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTA 3655
Query: 636 LKIPQTKACPKKTNT-TASAKVAP----VRVGTQAPRKAGTATSPAGSSPAVA--GGTQR 688
+P + P T+T +S+ V P + + T + T P ++ + G T
Sbjct: 3656 STLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLS 3715
Query: 689 PAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPV--LPGK 746
+S+ + S E + A SV +++ + S T PV P
Sbjct: 3716 TPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVS----TTPVTRFPES 3771
Query: 747 TGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKK----TQAKANPAAARAPSA 802
+ P++ V + S S + + + T+ ++ T +P + +PS
Sbjct: 3772 STPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSE 3831
Query: 803 KGTISAP-GKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQ 861
T+S P G T + + + V + S R S P V+T
Sbjct: 3832 ASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSER---STPLTTLLVST----- 3883
Query: 862 TGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAP-------- 913
T P G+S + + + T + T I A + +G+ P
Sbjct: 3884 TLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPS 3943
Query: 914 TP---------PGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDP 964
TP P TG + + + S S S TS K F P
Sbjct: 3944 TPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSS------TTTSFSTTKE---FTTP 3994
Query: 965 NRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTM 1024
+ A P + A STPR +T+ S+ S + TP T+V T
Sbjct: 3995 AMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATS-----------TPHTSTSVTTR 4043
Query: 1025 PTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGT 1084
P + S ESSR S P T + T P TS ST+V +
Sbjct: 4044 PV--------------TPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAV 4089
Query: 1085 NKLRKPKLPEVQ 1096
+ P +
Sbjct: 4090 TTMTTRTKPSTR 4101
Score = 53.1 bits (126), Expect = 2e-06
Identities = 100/444 (22%), Positives = 156/444 (35%), Gaps = 55/444 (12%)
Query: 833 NPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGK 892
NP+ +++ + + P V T +++T E S S+ S E+ T + P G
Sbjct: 88 NPEMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTED--TSSPTTPEGT 145
Query: 893 THQIRAALAPAKESPRK-----GAAPTP----------------PGKTGPSAAQAGKQDD 931
+ P++ES AP P P T A+ + +
Sbjct: 146 DVPMST---PSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPE 202
Query: 932 SGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA--QAQAASTPRKARA 989
S + + ++S+G P A +K + +TP AQA+S+P A
Sbjct: 203 STTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEG 262
Query: 990 SESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASS--SKESS 1047
+ + S S +P + L + ++ A I S +SS + E +
Sbjct: 263 PSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGT 322
Query: 1048 RISDGKKQEGPATQVDSAVGTLP-ATSPQST-SVQAKGTNKL-----RKPKLPEVQQATK 1100
I EG + T+P ATS ST S+ T+ L LP +AT
Sbjct: 323 SIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEAT- 381
Query: 1101 APESSDDSEDSSDSSSGSEEDGEGPQG----AKSAHTLVGPTPSRTETLVEETAAESSED 1156
S +S S GS P A S + P ++T V TA+E+S
Sbjct: 382 -------SMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVT-TASEASSS 433
Query: 1157 DVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAA 1216
A S+ + + G TP S TP S S ST D K + A
Sbjct: 434 PTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPV----DSKTQVTTSTEA 489
Query: 1217 GMLSPKTGGKEAASGTTPQKSRKP 1240
SP T + +TP + P
Sbjct: 490 SS-SPPTAEVNSMPTSTPSEGSTP 512
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 116 bits (290), Expect = 2e-25
Identities = 211/1120 (18%), Positives = 375/1120 (33%), Gaps = 142/1120 (12%)
Query: 148 VANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAG--QADSSSEDTSS 205
V N S S +K+ PS + + T + P K + S + S SE+ S
Sbjct: 66 VHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQES 125
Query: 206 SSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKK 265
SS + +++ + +S + +E + +VK K+
Sbjct: 126 SSSSSSSSSSSTIRKIKSSKNSAANRELQKKL-------------KVKDNKKNRTKKKPT 172
Query: 266 PE----EESESSEEGSESEEEAPAGTRSQ---VKASEKILQVRAASAPAKGTPGKGATPA 318
P+ +E+ S + + + P + +Q V S KI + + P P T
Sbjct: 173 PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPIN-PRPSLPPNSDTSK 231
Query: 319 PPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL-----LQAKASGKTSQVGA 373
+ ++ + +E + ++ + S+D +E+T +AK AK TS+V A
Sbjct: 232 ---ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA 288
Query: 374 ASAPAKESPRKGAA---PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPS 430
P E+ KG A P P T P + K + S + +E AP K +
Sbjct: 289 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 348
Query: 431 GKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALA 490
P+ A + + +P PAP PA +
Sbjct: 349 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK----------------------- 385
Query: 491 AMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSE 550
+ +P +P+ KPA T P P P + P TP +E + ++ +
Sbjct: 386 SAPTTPKEPAPTTPK-KPAPTTPKEP-----APTTPKEPTPTTPKEPAPTTKEPAPTTPK 439
Query: 551 ESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAV-QVKAEKPMDNSE 609
E + ++ P AP K PA P++ P + P + +
Sbjct: 440 EPAPTA----PKKPAPTTPK------------EPAPTTPKEPAPTTTKEPSPTTPKEPAP 483
Query: 610 SSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKA 669
++ +S+ + E AP +A P P T P T A P + P K
Sbjct: 484 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KE 542
Query: 670 GTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASV 729
T+P +P T++PA ++ E + + ++T + + L
Sbjct: 543 PAPTTPKEPAPTT---TKKPA-PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 598
Query: 730 PVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQ 789
P + + AP P + PT + A +++ + E A +P + + K
Sbjct: 599 PAP-TTPEELAPTTPEEPTPTTPEEPA--PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 655
Query: 790 AKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPS 849
A P + KGT K A K+ +P ++ P ST + + P
Sbjct: 656 APTTPKETAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 714
Query: 850 VGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRK 909
A T P+E + ++ +E A P G AP + K
Sbjct: 715 --------GTAPTTPKEPAPTTPKEP---------APTTPKG--------TAP---TTLK 746
Query: 910 GAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPA 969
APT P K P+ + G +S SD T+ K P +P
Sbjct: 747 EPAPTTPKK--PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 804
Query: 970 GPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCL--------TPGIRTNV 1021
P P STP + + +S + + P + L P +T
Sbjct: 805 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPA 864
Query: 1022 VTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQA 1081
T P K + ++ E++ + +E T + + AT+ Q TS
Sbjct: 865 ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTT 924
Query: 1082 KGTNKLRKPKLPEVQQATKAPESSDDSED-SSDSSSGSEEDGEGPQGAKSAHTLVGPTPS 1140
+ T K+ ++ T AP+ + + ++ E+ P+ + P P
Sbjct: 925 QDTTPF---KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQ 981
Query: 1141 RTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAA 1200
+ T A P + P TP + + P+L+ + ++ +
Sbjct: 982 K------PTKAPKKPTSTKKP--KTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAML- 1032
Query: 1201 KDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKP 1240
+ P ++PK+ A G TP +P
Sbjct: 1033 --QTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRP 1070
Score = 114 bits (286), Expect = 5e-25
Identities = 172/875 (19%), Positives = 301/875 (34%), Gaps = 121/875 (13%)
Query: 54 QQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVL 113
+QTS G+++ +KT D TS+ + +AET P L +
Sbjct: 253 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP-KAETTTKGPALTTPKEPT- 310
Query: 114 GADLPSSMKEKAKAE-------TEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSAN 166
P++ KE A T K+ T P P T K+ +P + EP+
Sbjct: 311 ----PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 366
Query: 167 TTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDE-----TDVEGKPSVK-- 219
T PA +P + A ++ ++ + ++ + T E P+
Sbjct: 367 TP---------KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 417
Query: 220 --PAQVKASSVSTKE----SPARKAAPAPGKVGDVTPQVKGGALP--PAKRAKKPEEESE 271
P K + +TKE +P A AP K TP+ P PA K +
Sbjct: 418 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 477
Query: 272 SSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGK---AGAVAS 328
E + + AP T+ + K A + P + +P PAP A
Sbjct: 478 PKEPAPTTTKSAPTTTKEPAPTTTK----SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 533
Query: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPR--KGA 386
+ P+E + ++ +E + + + PA + + T + A + P K +P +
Sbjct: 534 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTT--PKEPAPTTPKETAPTTPKKLTPTTPEKL 591
Query: 387 APAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKES 446
AP P K P + A E+ ++ E + A A + K P PA +
Sbjct: 592 APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 651
Query: 447 PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDRE----------ALAAMNAAQ 496
P++ AP P++T P + ++ ++ + + +E + A
Sbjct: 652 PKE-PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 710
Query: 497 VKPLGKSPQV--KPASTMGMGPLG---KGAGPVPPGKVGPATPSAQVGKWEEDSESSSEE 551
P G +P +PA T P KG P + P TP K E ++
Sbjct: 711 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGP 769
Query: 552 SSDSSDGEVPTA---VAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS 608
+S +SD PT AP K KP + + PP V+ ++P
Sbjct: 770 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 829
Query: 609 ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRK 668
+S +ES+ +E P A+ + +P + +T A K TT + K
Sbjct: 830 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA--------------K 875
Query: 669 AGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAAS 728
T ++P + ++++++ E +E ++ A +
Sbjct: 876 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTES-------------------KITATT 916
Query: 729 VPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
V + Q T P T K + + ++ E + E A P
Sbjct: 917 TQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKD-------- 968
Query: 789 QAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVP 848
RA ++K T P K A + K P VR P+ + + +++P
Sbjct: 969 ---------RATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 1019
Query: 849 SV---GKAVATAAQAQTGPEEDSGSSEEESDSEEE 880
+ + Q T P + S E + + E
Sbjct: 1020 ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSE 1054
Score = 106 bits (265), Expect = 1e-22
Identities = 217/993 (21%), Positives = 351/993 (35%), Gaps = 118/993 (11%)
Query: 419 SEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPA------AAQVQVGKQE 472
+E P S KAP AS K + ++ P +KT + V + +
Sbjct: 64 AEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQ 123
Query: 473 EDSRSSSEESDSD--REALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVG 530
E S SSS S S R+ ++ N+A + L K +VK K P
Sbjct: 124 ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNK--------KNRTKKKPTPKP 175
Query: 531 PATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQ 590
P A G D + ++ ++S + +V T+ K + P S +K
Sbjct: 176 PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSL 235
Query: 591 KAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAK---PALKIPQTKACPKK 647
E N ++S + + S + ++ AK P K+ K PK
Sbjct: 236 TVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV-LAKPTPKA 294
Query: 648 TNTTASAKVAPVRVGTQAPRKAGTATSPAGSSP-AVAGGTQRPAEDSSSSEESDSEEEKT 706
TT + + T K +T+P +P + P E + ++ +S K
Sbjct: 295 ETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE 354
Query: 707 GLAVTVGQ-----AKSVGKGLQVKAASVPVKG--SLGQGTAPVLPGKTGPTVTQVKA--E 757
T + K + A K + + AP P K PT + A
Sbjct: 355 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 414
Query: 758 KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAA 817
+E + ++ +E +P K K P + P A T P T
Sbjct: 415 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP-APTTPKEPAPTTT--- 470
Query: 818 QAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE--- 874
K+ SP+ K P S A + A T A T P+E S ++ +E
Sbjct: 471 --KEPSPTTPKEPAPTTTKS-------APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 521
Query: 875 SDSEEEAETLAQVKPSGKTHQIRAALAPAKESP--RKGAAPTPPGKTGP-----SAAQAG 927
+ +E A T + KP+ T + A P + +P K APT P + P +A
Sbjct: 522 TTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 580
Query: 928 KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPN-RSPAGPAATPAQAQAASTPRK 986
K+ + + + + E PA T ++ P +P +P PA T +A A +TP++
Sbjct: 581 KKLTPTTPEKLAPTTPEKPAPTTPEEL--APTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 638
Query: 987 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTM----PTAHPRIAPKASMAGASS 1042
+ + ++ E P T T T+ PT + APK +A ++
Sbjct: 639 PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTT 697
Query: 1043 SKESSRISD-------------GKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRK 1089
+ +S D K+ P T + A T T+P + A T K
Sbjct: 698 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 757
Query: 1090 PKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAK--SAHTLVGPTPSRTETLVE 1147
PK TK P S+ +SD + + P K + T P P+ ET
Sbjct: 758 PK-ELAPTTTKGPTST-----TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 811
Query: 1148 ETAAESSEDDVVAPSQSLLS-GYMTPGLT-PANSQASKATPKLDSSPSVSSTLAAKDDPD 1205
T+ S+ P+ S TP L+ +A + +PK P+ + A K +
Sbjct: 812 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT 871
Query: 1206 GKQEAKPQQAAGMLSPKTG------GKEAASGTTPQKSRKPKKGAGNPQASTLALQSNIT 1259
+ K + +P+T KE A TT +K+ + K A Q ++ Q
Sbjct: 872 TTAKDKTTERDLRTTPETTTAAPKMTKETA--TTTEKTTESKITATTTQVTSTTTQDT-- 927
Query: 1260 QCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAA 1319
P+ + + KV T KK + TT E K E+ K K A
Sbjct: 928 -----TPFKITTLKTTTLAPKVTT------TKKTI-TTTEIMNKPEETAKPKDRATNSKA 975
Query: 1320 RTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1352
TP+ +K K +P+K ++T K K
Sbjct: 976 TTPKPQKPTK-----------APKKPTSTKKPK 997
Score = 106 bits (265), Expect = 1e-22
Identities = 193/1038 (18%), Positives = 359/1038 (34%), Gaps = 109/1038 (10%)
Query: 58 ELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAE-----AETAKATPRLASTNSSV 112
EL +K K +++ + KK P E+ + + +T+ ST+ +
Sbjct: 152 ELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKI 211
Query: 113 LGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSP----RKSAEPSANTT 168
A P + + ++ + +T ++ T +T + K ++ + T
Sbjct: 212 TTAK-PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQ 270
Query: 169 LVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSV 228
+ +T + P AKP + + T T + S P + +++
Sbjct: 271 SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI 330
Query: 229 STKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTR 288
+ + ++ AP K TP+ P K+P + + ++E AP T+
Sbjct: 331 KSAPTTPKEPAPTTTKSAPTTPKE-----PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 385
Query: 289 SQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSD 348
S ++ PA TP K A P A + P+E + ++ E +
Sbjct: 386 SAPTTPKE---------PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 436
Query: 349 SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP--PGKTGPAVAKAQAGKR 406
+ +E PA A K + T + A + P + +P P+P P + P K+
Sbjct: 437 TPKE-PAPTA--PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 493
Query: 407 EEDSQSSSEESDSEEEAPAQA---KPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAA 463
+E + ++++ + + + P+ +P+ P+ A + P K +P PAP PA
Sbjct: 494 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 553
Query: 464 AQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGP 523
+ KP +P+ +PA T K P
Sbjct: 554 TTTK------------------------------KPAPTTPK-EPAPT-----TPKETAP 577
Query: 524 VPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPT-S 582
P K+ P TP E ++ E + E PT P + A T
Sbjct: 578 TTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK 637
Query: 583 SPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTK 642
PA P++ P + A + + + + + PA T + P P T
Sbjct: 638 EPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 697
Query: 643 ACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPA--EDSSSSEESD 700
P T A P P K T+P +P GT E + ++ +
Sbjct: 698 KEPTSTTCDKPAPTTPKGTAPTTP-KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP 756
Query: 701 SEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQE 760
+ +E A + KG + P + + TAP P + PT + A
Sbjct: 757 APKE---------LAPTTTKGPTSTTSDKPAP-TTPKETAPTTPKEPAPTTPKKPA---P 803
Query: 761 DSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAK 820
+ + + SE + + + T++ K+ ++ P + P+ K ++P +
Sbjct: 804 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE----PGVPT 859
Query: 821 QRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAV-ATAAQAQTGPEEDSGSSEEESDSEE 879
++P+ KP + R + P A + T E+ + S + ++
Sbjct: 860 TKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 919
Query: 880 EAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP-PGKTGPSAAQAGKQDDSGSSSEE 938
+ T P T LAP + +K T K +A + +S +++ +
Sbjct: 920 TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPK 979
Query: 939 SDSDGEAPAAVTSAQVIKPPLIFVDPNRSPA-----------GPAATPAQAQAASTPRKA 987
+AP TS + K P +P P + A+A +T R
Sbjct: 980 PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPN 1039
Query: 988 RASESTARSSSSESED----EDVIPATQCLTPGIRTNVVTMPTAH-PRIAPKASMAGASS 1042
+ S + +SED E P L P + VT + PR+ + +
Sbjct: 1040 QTPNSKLVEVNPKSEDAGGAEGETP-HMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPML 1098
Query: 1043 SKESSRISDGKKQEGPAT 1060
S E++ I +GK +G T
Sbjct: 1099 SDETN-ICNGKPVDGLTT 1115
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 116 bits (290), Expect = 2e-25
Identities = 211/1120 (18%), Positives = 375/1120 (33%), Gaps = 142/1120 (12%)
Query: 148 VANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAG--QADSSSEDTSS 205
V N S S +K+ PS + + T + P K + S + S SE+ S
Sbjct: 107 VHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQES 166
Query: 206 SSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKK 265
SS + +++ + +S + +E + +VK K+
Sbjct: 167 SSSSSSSSSSSTIRKIKSSKNSAANRELQKKL-------------KVKDNKKNRTKKKPT 213
Query: 266 PE----EESESSEEGSESEEEAPAGTRSQ---VKASEKILQVRAASAPAKGTPGKGATPA 318
P+ +E+ S + + + P + +Q V S KI + + P P T
Sbjct: 214 PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPIN-PRPSLPPNSDTSK 272
Query: 319 PPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL-----LQAKASGKTSQVGA 373
+ ++ + +E + ++ + S+D +E+T +AK AK TS+V A
Sbjct: 273 ---ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA 329
Query: 374 ASAPAKESPRKGAA---PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPS 430
P E+ KG A P P T P + K + S + +E AP K +
Sbjct: 330 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 389
Query: 431 GKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALA 490
P+ A + + +P PAP PA +
Sbjct: 390 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK----------------------- 426
Query: 491 AMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSE 550
+ +P +P+ KPA T P P P + P TP +E + ++ +
Sbjct: 427 SAPTTPKEPAPTTPK-KPAPTTPKEP-----APTTPKEPTPTTPKEPAPTTKEPAPTTPK 480
Query: 551 ESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAV-QVKAEKPMDNSE 609
E + ++ P AP K PA P++ P + P + +
Sbjct: 481 EPAPTA----PKKPAPTTPK------------EPAPTTPKEPAPTTTKEPSPTTPKEPAP 524
Query: 610 SSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKA 669
++ +S+ + E AP +A P P T P T A P + P K
Sbjct: 525 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KE 583
Query: 670 GTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASV 729
T+P +P T++PA ++ E + + ++T + + L
Sbjct: 584 PAPTTPKEPAPTT---TKKPA-PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 639
Query: 730 PVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQ 789
P + + AP P + PT + A +++ + E A +P + + K
Sbjct: 640 PAP-TTPEELAPTTPEEPTPTTPEEPA--PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 696
Query: 790 AKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPS 849
A P + KGT K A K+ +P ++ P ST + + P
Sbjct: 697 APTTPKETAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 755
Query: 850 VGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRK 909
A T P+E + ++ +E A P G AP + K
Sbjct: 756 --------GTAPTTPKEPAPTTPKEP---------APTTPKG--------TAP---TTLK 787
Query: 910 GAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPA 969
APT P K P+ + G +S SD T+ K P +P
Sbjct: 788 EPAPTTPKK--PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 845
Query: 970 GPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCL--------TPGIRTNV 1021
P P STP + + +S + + P + L P +T
Sbjct: 846 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPA 905
Query: 1022 VTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQA 1081
T P K + ++ E++ + +E T + + AT+ Q TS
Sbjct: 906 ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTT 965
Query: 1082 KGTNKLRKPKLPEVQQATKAPESSDDSED-SSDSSSGSEEDGEGPQGAKSAHTLVGPTPS 1140
+ T K+ ++ T AP+ + + ++ E+ P+ + P P
Sbjct: 966 QDTTPF---KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQ 1022
Query: 1141 RTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAA 1200
+ T A P + P TP + + P+L+ + ++ +
Sbjct: 1023 K------PTKAPKKPTSTKKP--KTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAML- 1073
Query: 1201 KDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKP 1240
+ P ++PK+ A G TP +P
Sbjct: 1074 --QTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRP 1111
Score = 114 bits (286), Expect = 5e-25
Identities = 172/875 (19%), Positives = 301/875 (34%), Gaps = 121/875 (13%)
Query: 54 QQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVL 113
+QTS G+++ +KT D TS+ + +AET P L +
Sbjct: 294 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP-KAETTTKGPALTTPKEPT- 351
Query: 114 GADLPSSMKEKAKAE-------TEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSAN 166
P++ KE A T K+ T P P T K+ +P + EP+
Sbjct: 352 ----PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 407
Query: 167 TTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDE-----TDVEGKPSVK-- 219
T PA +P + A ++ ++ + ++ + T E P+
Sbjct: 408 TP---------KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 458
Query: 220 --PAQVKASSVSTKE----SPARKAAPAPGKVGDVTPQVKGGALP--PAKRAKKPEEESE 271
P K + +TKE +P A AP K TP+ P PA K +
Sbjct: 459 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 518
Query: 272 SSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGK---AGAVAS 328
E + + AP T+ + K A + P + +P PAP A
Sbjct: 519 PKEPAPTTTKSAPTTTKEPAPTTTK----SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 574
Query: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPR--KGA 386
+ P+E + ++ +E + + + PA + + T + A + P K +P +
Sbjct: 575 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTT--PKEPAPTTPKETAPTTPKKLTPTTPEKL 632
Query: 387 APAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKES 446
AP P K P + A E+ ++ E + A A + K P PA +
Sbjct: 633 APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 692
Query: 447 PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDRE----------ALAAMNAAQ 496
P++ AP P++T P + ++ ++ + + +E + A
Sbjct: 693 PKE-PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 751
Query: 497 VKPLGKSPQV--KPASTMGMGPLG---KGAGPVPPGKVGPATPSAQVGKWEEDSESSSEE 551
P G +P +PA T P KG P + P TP K E ++
Sbjct: 752 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGP 810
Query: 552 SSDSSDGEVPTA---VAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS 608
+S +SD PT AP K KP + + PP V+ ++P
Sbjct: 811 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 870
Query: 609 ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRK 668
+S +ES+ +E P A+ + +P + +T A K TT + K
Sbjct: 871 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA--------------K 916
Query: 669 AGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAAS 728
T ++P + ++++++ E +E ++ A +
Sbjct: 917 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTES-------------------KITATT 957
Query: 729 VPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
V + Q T P T K + + ++ E + E A P
Sbjct: 958 TQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKD-------- 1009
Query: 789 QAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVP 848
RA ++K T P K A + K P VR P+ + + +++P
Sbjct: 1010 ---------RATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 1060
Query: 849 SV---GKAVATAAQAQTGPEEDSGSSEEESDSEEE 880
+ + Q T P + S E + + E
Sbjct: 1061 ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSE 1095
Score = 106 bits (265), Expect = 1e-22
Identities = 217/993 (21%), Positives = 351/993 (35%), Gaps = 118/993 (11%)
Query: 419 SEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPA------AAQVQVGKQE 472
+E P S KAP AS K + ++ P +KT + V + +
Sbjct: 105 AEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQ 164
Query: 473 EDSRSSSEESDSD--REALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVG 530
E S SSS S S R+ ++ N+A + L K +VK K P
Sbjct: 165 ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNK--------KNRTKKKPTPKP 216
Query: 531 PATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQ 590
P A G D + ++ ++S + +V T+ K + P S +K
Sbjct: 217 PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSL 276
Query: 591 KAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAK---PALKIPQTKACPKK 647
E N ++S + + S + ++ AK P K+ K PK
Sbjct: 277 TVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV-LAKPTPKA 335
Query: 648 TNTTASAKVAPVRVGTQAPRKAGTATSPAGSSP-AVAGGTQRPAEDSSSSEESDSEEEKT 706
TT + + T K +T+P +P + P E + ++ +S K
Sbjct: 336 ETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE 395
Query: 707 GLAVTVGQ-----AKSVGKGLQVKAASVPVKG--SLGQGTAPVLPGKTGPTVTQVKA--E 757
T + K + A K + + AP P K PT + A
Sbjct: 396 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 455
Query: 758 KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAA 817
+E + ++ +E +P K K P + P A T P T
Sbjct: 456 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP-APTTPKEPAPTTT--- 511
Query: 818 QAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE--- 874
K+ SP+ K P S A + A T A T P+E S ++ +E
Sbjct: 512 --KEPSPTTPKEPAPTTTKS-------APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 562
Query: 875 SDSEEEAETLAQVKPSGKTHQIRAALAPAKESP--RKGAAPTPPGKTGP-----SAAQAG 927
+ +E A T + KP+ T + A P + +P K APT P + P +A
Sbjct: 563 TTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 621
Query: 928 KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPN-RSPAGPAATPAQAQAASTPRK 986
K+ + + + + E PA T ++ P +P +P PA T +A A +TP++
Sbjct: 622 KKLTPTTPEKLAPTTPEKPAPTTPEEL--APTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 679
Query: 987 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTM----PTAHPRIAPKASMAGASS 1042
+ + ++ E P T T T+ PT + APK +A ++
Sbjct: 680 PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTT 738
Query: 1043 SKESSRISD-------------GKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRK 1089
+ +S D K+ P T + A T T+P + A T K
Sbjct: 739 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 798
Query: 1090 PKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAK--SAHTLVGPTPSRTETLVE 1147
PK TK P S+ +SD + + P K + T P P+ ET
Sbjct: 799 PK-ELAPTTTKGPTST-----TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 852
Query: 1148 ETAAESSEDDVVAPSQSLLS-GYMTPGLT-PANSQASKATPKLDSSPSVSSTLAAKDDPD 1205
T+ S+ P+ S TP L+ +A + +PK P+ + A K +
Sbjct: 853 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT 912
Query: 1206 GKQEAKPQQAAGMLSPKTG------GKEAASGTTPQKSRKPKKGAGNPQASTLALQSNIT 1259
+ K + +P+T KE A TT +K+ + K A Q ++ Q
Sbjct: 913 TTAKDKTTERDLRTTPETTTAAPKMTKETA--TTTEKTTESKITATTTQVTSTTTQDT-- 968
Query: 1260 QCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAA 1319
P+ + + KV T KK + TT E K E+ K K A
Sbjct: 969 -----TPFKITTLKTTTLAPKVTT------TKKTI-TTTEIMNKPEETAKPKDRATNSKA 1016
Query: 1320 RTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1352
TP+ +K K +P+K ++T K K
Sbjct: 1017 TTPKPQKPTK-----------APKKPTSTKKPK 1038
Score = 106 bits (265), Expect = 1e-22
Identities = 193/1038 (18%), Positives = 359/1038 (34%), Gaps = 109/1038 (10%)
Query: 58 ELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAE-----AETAKATPRLASTNSSV 112
EL +K K +++ + KK P E+ + + +T+ ST+ +
Sbjct: 193 ELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKI 252
Query: 113 LGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSP----RKSAEPSANTT 168
A P + + ++ + +T ++ T +T + K ++ + T
Sbjct: 253 TTAK-PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQ 311
Query: 169 LVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSV 228
+ +T + P AKP + + T T + S P + +++
Sbjct: 312 SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI 371
Query: 229 STKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTR 288
+ + ++ AP K TP+ P K+P + + ++E AP T+
Sbjct: 372 KSAPTTPKEPAPTTTKSAPTTPKE-----PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 426
Query: 289 SQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSD 348
S ++ PA TP K A P A + P+E + ++ E +
Sbjct: 427 SAPTTPKE---------PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 477
Query: 349 SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP--PGKTGPAVAKAQAGKR 406
+ +E PA A K + T + A + P + +P P+P P + P K+
Sbjct: 478 TPKE-PAPTA--PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 534
Query: 407 EEDSQSSSEESDSEEEAPAQA---KPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAA 463
+E + ++++ + + + P+ +P+ P+ A + P K +P PAP PA
Sbjct: 535 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 594
Query: 464 AQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGP 523
+ KP +P+ +PA T K P
Sbjct: 595 TTTK------------------------------KPAPTTPK-EPAPT-----TPKETAP 618
Query: 524 VPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPT-S 582
P K+ P TP E ++ E + E PT P + A T
Sbjct: 619 TTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK 678
Query: 583 SPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTK 642
PA P++ P + A + + + + + PA T + P P T
Sbjct: 679 EPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 738
Query: 643 ACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPA--EDSSSSEESD 700
P T A P P K T+P +P GT E + ++ +
Sbjct: 739 KEPTSTTCDKPAPTTPKGTAPTTP-KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP 797
Query: 701 SEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQE 760
+ +E A + KG + P + + TAP P + PT + A
Sbjct: 798 APKE---------LAPTTTKGPTSTTSDKPAP-TTPKETAPTTPKEPAPTTPKKPA---P 844
Query: 761 DSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAK 820
+ + + SE + + + T++ K+ ++ P + P+ K ++P +
Sbjct: 845 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE----PGVPT 900
Query: 821 QRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAV-ATAAQAQTGPEEDSGSSEEESDSEE 879
++P+ KP + R + P A + T E+ + S + ++
Sbjct: 901 TKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 960
Query: 880 EAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP-PGKTGPSAAQAGKQDDSGSSSEE 938
+ T P T LAP + +K T K +A + +S +++ +
Sbjct: 961 TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPK 1020
Query: 939 SDSDGEAPAAVTSAQVIKPPLIFVDPNRSPA-----------GPAATPAQAQAASTPRKA 987
+AP TS + K P +P P + A+A +T R
Sbjct: 1021 PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPN 1080
Query: 988 RASESTARSSSSESED----EDVIPATQCLTPGIRTNVVTMPTAH-PRIAPKASMAGASS 1042
+ S + +SED E P L P + VT + PR+ + +
Sbjct: 1081 QTPNSKLVEVNPKSEDAGGAEGETP-HMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPML 1139
Query: 1043 SKESSRISDGKKQEGPAT 1060
S E++ I +GK +G T
Sbjct: 1140 SDETN-ICNGKPVDGLTT 1156
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 115 bits (288), Expect = 3e-25
Identities = 155/595 (26%), Positives = 241/595 (40%), Gaps = 98/595 (16%)
Query: 159 KSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSS-SDETDVEGKPS 217
+ E + T V+E EE+ + G + G +A+ E+T S ++E K +
Sbjct: 459 EQTEETQVTEEVTEEEEKEAKEEEGKEEEGG--EEEEAEGGEEETKSPPAEEAASPEKEA 516
Query: 218 VKPAQVKASSVSTKESPARKAAPAPGKVGDV----TPQVKGGALPPAKRAKKPEEESESS 273
P + +A S + +SP ++ A +P +V +P + PP AK PE+E S
Sbjct: 517 KSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPP--EAKSPEKEEAKS 574
Query: 274 EEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGA-----VAS 328
+S E+A + + + K+ + A +P K A P K A V S
Sbjct: 575 PAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKS 634
Query: 329 QTKAGKPEEDSESSSEE--SSDSEEETPAAKALLQAKASGKTSQVGA------------A 374
KA P ++ S E+ S + EE KA KA K+ + A
Sbjct: 635 PEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694
Query: 375 SAPAKE---SPRKGAAPAPPGKTGPAVAKA----QAGKREEDSQSSSEESDSEEEA--PA 425
+P KE SP K +P P AK+ +A E+ EE+ S E+A P
Sbjct: 695 KSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPE 754
Query: 426 QAK------PSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSS 479
+AK P K P A +PA + P K +P P A+ + +ED+++
Sbjct: 755 KAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPL---KEDAKAPE 811
Query: 480 EESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKV----GPATPS 535
+E E + VK K +VK PP K PATP
Sbjct: 812 KEIPKKEEV-----KSPVKEEEKPQEVKVKE--------------PPKKAEEEKAPATP- 851
Query: 536 AQVGKWEEDSESSSEES--SDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAK---GPPQ 590
K EE +S EE+ ++ +V PA EK + ++AK + K P+
Sbjct: 852 ----KTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPE 907
Query: 591 KAGPVAVQVKAE-KPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 649
K P V+VK + KP + +E +++ D A ++E +KPA K +A P+K +
Sbjct: 908 KEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKE--------PSKPAEK---KEAAPEKKD 956
Query: 650 T-TASAKVAPVRVGTQAPRKAGTAT-SPAGSSPAVAGGTQRPAEDSSSSEESDSE 702
T AK + T+A K T S S P AE SSS+++ DS+
Sbjct: 957 TKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKA-----EKAEKSSSTDQKDSK 1006
Score = 115 bits (288), Expect = 3e-25
Identities = 134/604 (22%), Positives = 232/604 (38%), Gaps = 87/604 (14%)
Query: 542 EEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKA 601
EE+ E+ EE + GE +E++ G + K + P+K V+ +A
Sbjct: 473 EEEKEAKEEEGKEEEGGE--------EEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEA 524
Query: 602 EKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRV 661
+ P + +E + S ++P + + A P+ K+ P+K + A+V
Sbjct: 525 KSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKS-PEKEEAKSPAEV----- 578
Query: 662 GTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKG 721
++P KA + SPA A ++ S EE+ S E
Sbjct: 579 --KSPEKAKSPAKEEAKSPAEAKSPEKAK--SPVKEEAKSPAE----------------- 617
Query: 722 LQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSE-EESDSEEAAASPAQ 780
A PVK + A V + + T+ +A+ E ++S E EE+ S E A SP
Sbjct: 618 -----AKSPVKEE-AKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSP-- 669
Query: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
VK K + +P A A S + S + + +SP K K PV+ S
Sbjct: 670 VKAEAKSPEKAKSPVKAEAKSPEKAKSP--------VKEEAKSPEKAKSPVKEEAKSPEK 721
Query: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
A+ P K A + P ++ S E++ S E+A+TL P KT A
Sbjct: 722 AKSPV------KEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEAR 775
Query: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ-----VI 955
+PA + P K +P P A++ ++D+ + +E E + V + +
Sbjct: 776 SPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKV 835
Query: 956 KPPLIFVDPNRSPAGP----------------AATPAQAQAASTPRKARASESTARSSSS 999
K P + ++PA P A + + P + ES +
Sbjct: 836 KEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKE 895
Query: 1000 ESEDEDVIPATQCLTPG-IRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGP 1058
E+ED+ +P + P + P +A K + +KE S+ ++ K+
Sbjct: 896 EAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKE--PDDAKAKEPSKPAEKKEAAPE 953
Query: 1059 ATQVDSAVGTLPATSPQSTSVQAKGTNKL--RKPKLPEVQQATKAPESSDDSEDSSDSSS 1116
P P+ T +AK +K ++P P+ ++A K+ SS D +DS
Sbjct: 954 KKDTKEEKAKKPEEKPK-TEAKAKEDDKTLSKEPSKPKAEKAEKS--SSTDQKDSKPPEK 1010
Query: 1117 GSEE 1120
+E+
Sbjct: 1011 ATED 1014
Score = 110 bits (274), Expect = 1e-23
Identities = 150/690 (21%), Positives = 254/690 (36%), Gaps = 102/690 (14%)
Query: 244 KVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVK-ASEKILQVRA 302
K+ V+ +K + K +K E+E+ EE +E + T + K A E+ +
Sbjct: 428 KIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEE 487
Query: 303 ASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQA 362
+ G+ T +PP + A + +E+++S +E S +EE + +
Sbjct: 488 GGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSP 547
Query: 363 KASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE 422
+ + ++ A S P +SP K A +P P AK+ A ++ S E+ S E+
Sbjct: 548 EKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPA----KEEAKSPAEAKSPEK 603
Query: 423 APAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEES 482
A + K K+P A +P KE + A P K + + + E+ EE+
Sbjct: 604 AKSPVKEEAKSP--AEAKSPVKEEAKSPAEVKSPEK-AKSPTKEEAKSPEKAKSPEKEEA 660
Query: 483 DSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWE 542
S +A + VK KSP+ K PV P
Sbjct: 661 KSPEKA-----KSPVKAEAKSPE-------------KAKSPVKAEAKSP----------- 691
Query: 543 EDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAE 602
E ++S +E + S + A +P +E++ P AK P + PV + K+
Sbjct: 692 EKAKSPVKEEAKSPE----KAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSP 747
Query: 603 KPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVG 662
+ + E ++ + + PA A PA K P+ AK +PV+
Sbjct: 748 EKAKSPEKAKTLDVKSPEAKTPAKEEA--RSPADKFPE------------KAK-SPVKEE 792
Query: 663 TQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL 722
++P KA SP ED+ + E+ ++E+ V K K
Sbjct: 793 VKSPEKA--------KSPL--------KEDAKAPEKEIPKKEEVKSPV-----KEEEKPQ 831
Query: 723 QVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVK 782
+VK P K + A P + K K+E++ E E PA K
Sbjct: 832 EVKVKEPPKKAEEEKAPAT-------PKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884
Query: 783 TSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLAR 842
K +AK A K + P K A + K+ + K K V + A+
Sbjct: 885 PKESKVEAKKEEA-----EDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAK 939
Query: 843 GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP 902
P+ A + + PE+ E+ EE+ +T A+ K KT +
Sbjct: 940 EPSK---------PAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPK 990
Query: 903 AKESPRKGAA----PTPPGKTGPSAAQAGK 928
A+++ + + PP K A GK
Sbjct: 991 AEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
Score = 105 bits (261), Expect = 4e-22
Identities = 130/641 (20%), Positives = 243/641 (37%), Gaps = 69/641 (10%)
Query: 811 KVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA----AQAQTGPEE 866
K+ + + K +S K+K V + TV+ V + V A+ + G EE
Sbjct: 428 KIPSVSTHIKVKSEEKIKV-VEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEE 486
Query: 867 DSGSSEEESDSEEE-----AETLAQVKPSGKTHQIRAALAPAK-ESPRKGAAPTPPGKTG 920
+ G EE EEE AE A + K+ A +PA+ +SP K A +P
Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKS 546
Query: 921 PSAAQAGKQDDSGSSSEESDSDGE---APAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 977
P A++ ++++ S E + E +PA V S + K P A +PA+
Sbjct: 547 PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPA---------KEEAKSPAE 597
Query: 978 AQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAP-KAS 1036
A++ + E+ + + + E+ + +P PT +P KA
Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSP----EKAKSPTKEEAKSPEKAK 653
Query: 1037 MAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQ 1096
+K + K E + + + A SP+ K K + V+
Sbjct: 654 SPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVK 713
Query: 1097 QATKAPESS-----DDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAA 1151
+ K+PE + ++++ + S +E+ + P+ AKS P ++T + A
Sbjct: 714 EEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKS------PEKAKTLDVKSPEAK 767
Query: 1152 ESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDG--KQE 1209
++++ +P+ +P S +P + + + + K++ K+E
Sbjct: 768 TPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEE 827
Query: 1210 AKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPL 1269
KPQ+ PK +E A T + +K K P+ P P
Sbjct: 828 EKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEA--------------PKPK 873
Query: 1270 NEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKK 1329
E + + +V K +E ++++ D K + + K ++ D + K+K +
Sbjct: 874 VEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDA------KPKEKTE 927
Query: 1330 LGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMG 1389
+ E +A K A K + + K KK + ++ E ++ L K
Sbjct: 928 VAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSK--- 984
Query: 1390 TVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTK 1430
+ S PK++K +K S +KD + EK + K A K
Sbjct: 985 -----EPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
Score = 95.1 bits (235), Expect = 4e-19
Identities = 129/551 (23%), Positives = 202/551 (36%), Gaps = 66/551 (11%)
Query: 66 EEDAALQAKKTRVSDPISTSESSEEE------EEAEAETAKATPRLASTNSSVLGADLPS 119
EE+ A ++ S P + S E+E EEA++ +P S A++ S
Sbjct: 490 EEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSP---AEVKS 546
Query: 120 SMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSV 179
K K+ A+ E P K+ A + S + + A+ A + +++ E+
Sbjct: 547 PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKS 606
Query: 180 PAFGAAAKPGMVSAGQADSSSEDTSSSSDE-----TDVEGKPSVK---PAQVKASSVSTK 231
P A P + + + S E T E K K P + +A S
Sbjct: 607 PVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKA 666
Query: 232 ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEG-SESEEEAPAGTRSQ 290
+SP + A +P K VK A P K +EE++S E+ S +EEA + +++
Sbjct: 667 KSPVKAEAKSPEKAKS---PVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAK 723
Query: 291 VKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSE 350
E+ A +P K P KA + ++ K E+ S E
Sbjct: 724 SPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPE 783
Query: 351 EETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP---PGKTGPAVAKAQAGKRE 407
+ K +++ K+ A AP KE P+K +P K K K E
Sbjct: 784 KAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAE 843
Query: 408 ED----SQSSSEESDSE-EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPA-------- 454
E+ + + E+ DS+ EEAP + P P+V PA E P++ A
Sbjct: 844 EEKAPATPKTEEKKDSKKEEAPKKEAPK---PKVEEKKEPAVEKPKESKVEAKKEEAEDK 900
Query: 455 ----PPRKTGPAAAQV----------QVGKQEEDSRSSSEESDSDREALAAMNAAQVK-P 499
P K PA +V +V K+E D + E S + AA K
Sbjct: 901 KKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEE 960
Query: 500 LGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGE 559
K P+ KP + K P+ P A E+ +SSS + DS E
Sbjct: 961 KAKKPEEKPKTE------AKAKEDDKTLSKEPSKPKA-----EKAEKSSSTDQKDSKPPE 1009
Query: 560 VPTAVAPAQEK 570
T A+ K
Sbjct: 1010 KATEDKAAKGK 1020
Score = 90.5 bits (223), Expect = 1e-17
Identities = 119/540 (22%), Positives = 221/540 (40%), Gaps = 59/540 (10%)
Query: 751 VTQVKAEKQEDSESSEEESDSE---------------EAAASPAQVKTSVKKTQAKANPA 795
VT+ + ++ ++ E EEE E E AASP + S K +AK +PA
Sbjct: 470 VTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAK-SPA 528
Query: 796 AARAPSAKGTISAPGKVVT-AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAV 854
A++P K +P +V + A++ + +K P ++P+ A+ PA V S KA
Sbjct: 529 EAKSPE-KEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEE--AKSPAEVKSPEKAK 585
Query: 855 ATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAK-ESPRKGAAP 913
+ A + P E + +S +EEA++ A+ K K A +PA+ +SP K +P
Sbjct: 586 SPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVK----EEAKSPAEVKSPEKAKSP 641
Query: 914 TPPGKTGPSAAQAGKQDDSGSSSE-ESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPA-GP 971
T P A++ +++++ S + +S EA + + +K + +SP
Sbjct: 642 TKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEE 701
Query: 972 AATPAQAQA-----ASTPRKARA----SESTARSSSSESEDEDVIPATQCLTPGIRTNVV 1022
A +P +A++ A +P KA++ T + S ++E P +T V
Sbjct: 702 AKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDV 761
Query: 1023 TMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAK 1082
P A P A + + K + K+E + + + A +P+ + +
Sbjct: 762 KSPEAK---TPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKE 818
Query: 1083 GT-NKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSR 1141
+ +++ + P+ + + P+ +++ + + + ++D + + K P P +
Sbjct: 819 EVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKE----APKP-K 873
Query: 1142 TETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAK 1201
E E + E V A + P TP +K K D+ P + +A K
Sbjct: 874 VEEKKEPAVEKPKESKVEAKKEEAEDKKKVP--TPEKEAPAKVEVKEDAKPKEKTEVAKK 931
Query: 1202 --DDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNIT 1259
DD K+ +KP + KEAA K K KK P+ A + + T
Sbjct: 932 EPDDAKAKEPSKPAEK----------KEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKT 981
Score = 78.2 bits (191), Expect = 5e-14
Identities = 111/534 (20%), Positives = 198/534 (37%), Gaps = 96/534 (17%)
Query: 925 QAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTP 984
+ GK+++ G E + E + PP + SP A +P + +A S P
Sbjct: 481 EEGKEEEGGEEEEAEGGEEETKS---------PP---AEEAASPEKEAKSPVKEEAKS-P 527
Query: 985 RKARASESTARSSSSE--SEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASS 1042
+A++ E S +E S ++ PA + + P+A
Sbjct: 528 AEAKSPEKEEAKSPAEVKSPEKAKSPAKE----------------EAKSPPEAKSPEKEE 571
Query: 1043 SKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1102
+K + + +K + PA + A A SP+ K K V++ K+P
Sbjct: 572 AKSPAEVKSPEKAKSPAKE--EAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSP 629
Query: 1103 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPS 1162
E + S ++E+ + P+ AKS P + E E A + + +P
Sbjct: 630 AEVKSPEKAK---SPTKEEAKSPEKAKS--------PEKEEAKSPEKAKSPVKAEAKSPE 678
Query: 1163 QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAK-PQQAAGMLSP 1221
++ +P ++A K+ K S + K K+EAK P++A +
Sbjct: 679 KAK---------SPVKAEA-KSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKE 728
Query: 1222 KTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKV 1281
+ E A ++++ P+K +A TL ++S EA+ A
Sbjct: 729 EAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSP-------------EAKTPA----- 770
Query: 1282 LTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVS 1341
++E + D E ++ P +S +K K E +A
Sbjct: 771 -----KEEARSPADKFPEKAKS-------------PVKEEVKSPEKAKSPLKEDAKAPEK 812
Query: 1342 PEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKS 1401
K K ++ +VK K+ + A P+ E +K E + PK
Sbjct: 813 EIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKP 872
Query: 1402 KKEKKKSDKRKKDKE-----KKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1450
K E+KK +K KE KKE+ + KK T + E+P++ + K+ K E+T
Sbjct: 873 KVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKT 926
Score = 45.4 bits (106), Expect = 4e-04
Identities = 44/191 (23%), Positives = 84/191 (43%), Gaps = 13/191 (6%)
Query: 1266 PWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSK 1325
P+ L E + V ++ +E+ KVV+ +++ + E + ++ +
Sbjct: 419 PFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEA 478
Query: 1326 KKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKG--KGSLGSQGAKDEPEEE 1383
K+++ EGGE + T A ++A+ KE K K S PE+E
Sbjct: 479 KEEEGKEEEGGEEEEAEGGEEETKSPPA--EEAASPEKEAKSPVKEEAKSPAEAKSPEKE 536
Query: 1384 LQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKK--------KKAKKASTKDSESP 1435
K V+ +++ + KE+ KS K EK+E K +KAK + ++++SP
Sbjct: 537 EAKSPAEVKSPEKAKSPA-KEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP 595
Query: 1436 SQKKKKKKKKT 1446
++ K +K K+
Sbjct: 596 AEAKSPEKAKS 606
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 114 bits (286), Expect = 5e-25
Identities = 172/875 (19%), Positives = 301/875 (34%), Gaps = 121/875 (13%)
Query: 54 QQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVL 113
+QTS G+++ +KT D TS+ + +AET P L +
Sbjct: 160 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP-KAETTTKGPALTTPKEPT- 217
Query: 114 GADLPSSMKEKAKAE-------TEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSAN 166
P++ KE A T K+ T P P T K+ +P + EP+
Sbjct: 218 ----PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 273
Query: 167 TTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDE-----TDVEGKPSVK-- 219
T PA +P + A ++ ++ + ++ + T E P+
Sbjct: 274 TP---------KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 324
Query: 220 --PAQVKASSVSTKE----SPARKAAPAPGKVGDVTPQVKGGALP--PAKRAKKPEEESE 271
P K + +TKE +P A AP K TP+ P PA K +
Sbjct: 325 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 384
Query: 272 SSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGK---AGAVAS 328
E + + AP T+ + K A + P + +P PAP A
Sbjct: 385 PKEPAPTTTKSAPTTTKEPAPTTTK----SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 440
Query: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPR--KGA 386
+ P+E + ++ +E + + + PA + + T + A + P K +P +
Sbjct: 441 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTT--PKEPAPTTPKETAPTTPKKLTPTTPEKL 498
Query: 387 APAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKES 446
AP P K P + A E+ ++ E + A A + K P PA +
Sbjct: 499 APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 558
Query: 447 PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDRE----------ALAAMNAAQ 496
P++ AP P++T P + ++ ++ + + +E + A
Sbjct: 559 PKE-PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 617
Query: 497 VKPLGKSPQV--KPASTMGMGPLG---KGAGPVPPGKVGPATPSAQVGKWEEDSESSSEE 551
P G +P +PA T P KG P + P TP K E ++
Sbjct: 618 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGP 676
Query: 552 SSDSSDGEVPTA---VAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS 608
+S +SD PT AP K KP + + PP V+ ++P
Sbjct: 677 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 736
Query: 609 ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRK 668
+S +ES+ +E P A+ + +P + +T A K TT + K
Sbjct: 737 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA--------------K 782
Query: 669 AGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAAS 728
T ++P + ++++++ E +E ++ A +
Sbjct: 783 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTES-------------------KITATT 823
Query: 729 VPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
V + Q T P T K + + ++ E + E A P
Sbjct: 824 TQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKD-------- 875
Query: 789 QAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVP 848
RA ++K T P K A + K P VR P+ + + +++P
Sbjct: 876 ---------RATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 926
Query: 849 SV---GKAVATAAQAQTGPEEDSGSSEEESDSEEE 880
+ + Q T P + S E + + E
Sbjct: 927 ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSE 961
Score = 108 bits (271), Expect = 3e-23
Identities = 177/923 (19%), Positives = 308/923 (33%), Gaps = 116/923 (12%)
Query: 336 EEDSESSSEESSDSEEETPAAKAL-----LQAKASGKTSQVGAASAPAKESPRKGAA--- 387
+E + ++ + S+D +E+T +AK AK TS+V A P E+ KG A
Sbjct: 153 KETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTT 212
Query: 388 PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447
P P T P + K + S + +E AP K + P+ A + + +P
Sbjct: 213 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 272
Query: 448 RKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVK 507
PAP PA + + +P +P+ K
Sbjct: 273 TTPKEPAPTTTKEPAPTTTK-----------------------SAPTTPKEPAPTTPK-K 308
Query: 508 PASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPA 567
PA T P P P + P TP +E + ++ +E + ++ P AP
Sbjct: 309 PAPTTPKEP-----APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA----PKKPAPT 359
Query: 568 QEKSLGNILQAKPTSSPAKGPPQKAGPVAV-QVKAEKPMDNSESSEESSDSADSEEAPAA 626
K PA P++ P + P + + ++ +S+ + E AP
Sbjct: 360 TPK------------EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT 407
Query: 627 MTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGT 686
+A P P T P T A P + P K T+P +P T
Sbjct: 408 TKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KEPAPTTPKEPAPTT---T 463
Query: 687 QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGK 746
++PA ++ E + + ++T + + L P + + AP P +
Sbjct: 464 KKPA-PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP-TTPEELAPTTPEE 521
Query: 747 TGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTI 806
PT + A +++ + E A +P + + K A P + KGT
Sbjct: 522 PTPTTPEEPA--PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 579
Query: 807 SAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEE 866
K A K+ +P ++ P ST + + P A T P+E
Sbjct: 580 PTTLK-EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK--------GTAPTTPKE 630
Query: 867 DSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQA 926
+ ++ +E A P G AP + K APT P K P+ +
Sbjct: 631 PAPTTPKEP---------APTTPKG--------TAP---TTLKEPAPTTPKK--PAPKEL 668
Query: 927 GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 986
G +S SD T+ K P +P P P STP
Sbjct: 669 APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTT 728
Query: 987 ARASESTARSSSSESEDEDVIPATQCL--------TPGIRTNVVTMPTAHPRIAPKASMA 1038
+ + +S + + P + L P +T T P K +
Sbjct: 729 TKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 788
Query: 1039 GASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQA 1098
++ E++ + +E T + + AT+ Q TS + T K+ ++
Sbjct: 789 DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF---KITTLKTT 845
Query: 1099 TKAPESSDDSED-SSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDD 1157
T AP+ + + ++ E+ P+ + P P + T A
Sbjct: 846 TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK------PTKAPKKPTS 899
Query: 1158 VVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAG 1217
P + P TP + + P+L+ + ++ + + P
Sbjct: 900 TKKP--KTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAML---QTTTRPNQTPNSKLV 954
Query: 1218 MLSPKTGGKEAASGTTPQKSRKP 1240
++PK+ A G TP +P
Sbjct: 955 EVNPKSEDAGGAEGETPHMLLRP 977
Score = 105 bits (262), Expect = 3e-22
Identities = 192/1023 (18%), Positives = 354/1023 (34%), Gaps = 115/1023 (11%)
Query: 66 EEDAALQAKKTRVSDP-ISTSESSEEEEEAEAETAKA-TPRLASTNSSVLGADLPSSMKE 123
E + L +V+ P ST++ ++ + TAK PR + +S + ++ +
Sbjct: 87 EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNK 146
Query: 124 KAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFG 183
+ ET++ T N + ++ + T + +T + P
Sbjct: 147 ETTVETKET--------------TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 192
Query: 184 AAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPG 243
AKP + + T T + S P + +++ + + ++ AP
Sbjct: 193 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 252
Query: 244 KVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAA 303
K TP+ P K+P + + ++E AP T+S ++
Sbjct: 253 KSAPTTPKE-----PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE------- 300
Query: 304 SAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAK 363
PA TP K A P A + P+E + ++ E + + +E PA A K
Sbjct: 301 --PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE-PAPTA--PKK 355
Query: 364 ASGKTSQVGAASAPAKESPRKGAAPAP--PGKTGPAVAKAQAGKREEDSQSSSEESDSEE 421
+ T + A + P + +P P+P P + P K+ +E + ++++ + +
Sbjct: 356 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 415
Query: 422 EAPAQA---KPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSS 478
+ P+ +P+ P+ A + P K +P PAP PA +
Sbjct: 416 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK----------- 464
Query: 479 SEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQV 538
KP +P+ +PA T K P P K+ P TP
Sbjct: 465 -------------------KPAPTTPK-EPAPT-----TPKETAPTTPKKLTPTTPEKLA 499
Query: 539 GKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPT-SSPAKGPPQKAGPVAV 597
E ++ E + E PT P + A T PA P++ P
Sbjct: 500 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 559
Query: 598 QVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVA 657
+ A + + + + + PA T + P P T P T A
Sbjct: 560 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 619
Query: 658 PVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPA--EDSSSSEESDSEEEKTGLAVTVGQA 715
P P K T+P +P GT E + ++ + + +E A
Sbjct: 620 PKGTAPTTP-KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE---------LA 669
Query: 716 KSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAA 775
+ KG + P + + TAP P + PT + A + + + SE +
Sbjct: 670 PTTTKGPTSTTSDKPAP-TTPKETAPTTPKEPAPTTPKKPA---PTTPETPPPTTSEVST 725
Query: 776 ASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQ 835
+ + T++ K+ ++ P + P+ K ++P + ++P+ KP +
Sbjct: 726 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE----PGVPTTKTPAATKPEMTTTA 781
Query: 836 NSTVLARGPASVPSVGKAV-ATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTH 894
R + P A + T E+ + S + ++ + T P T
Sbjct: 782 KDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT 841
Query: 895 QIRAALAPAKESPRKGAAPTP-PGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ 953
LAP + +K T K +A + +S +++ + +AP TS +
Sbjct: 842 LKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTK 901
Query: 954 VIKPPLIFVDPNRSPA-----------GPAATPAQAQAASTPRKARASESTARSSSSESE 1002
K P +P P + A+A +T R + S + +SE
Sbjct: 902 KPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSE 961
Query: 1003 D----EDVIPATQCLTPGIRTNVVTMPTAH-PRIAPKASMAGASSSKESSRISDGKKQEG 1057
D E P L P + VT + PR+ + + S E++ I +GK +G
Sbjct: 962 DAGGAEGETP-HMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETN-ICNGKPVDG 1019
Query: 1058 PAT 1060
T
Sbjct: 1020 LTT 1022
Score = 38.1 bits (87), Expect = 0.062
Identities = 71/418 (16%), Positives = 129/418 (30%), Gaps = 30/418 (7%)
Query: 1042 SSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKA 1101
++ ++S K P + P+ P S + + ++ + + T
Sbjct: 100 TTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTN 159
Query: 1102 PESSDDSEDSSDSSSGSE--EDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVV 1159
++S D ++ + S+ ++ E A ++ L PTP T E
Sbjct: 160 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT 219
Query: 1160 APSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGML 1219
P + + P TP +++ TPK + + S +P +P
Sbjct: 220 TPKEPASTTPKEP--TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 277
Query: 1220 SPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVV 1279
T KE A TT PK+ A +P P + +
Sbjct: 278 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPK---------------KPAPTTPKEPAPTTP 322
Query: 1280 KVLTELLEQE----RKKVVDTTKESSRKGWESRKRKLSGDQPAARTPR----SKKKKKLG 1331
K T +E K+ TT + + + +PA TP+ + K+
Sbjct: 323 KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 382
Query: 1332 AGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTV 1391
A + + TT+K A S K+ + + A P+E T
Sbjct: 383 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT---TP 439
Query: 1392 EGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1449
+ + PK + +K + A T E+ KK T E+
Sbjct: 440 KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 497
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 114 bits (286), Expect = 5e-25
Identities = 172/875 (19%), Positives = 301/875 (34%), Gaps = 121/875 (13%)
Query: 54 QQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVL 113
+QTS G+++ +KT D TS+ + +AET P L +
Sbjct: 201 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP-KAETTTKGPALTTPKEPT- 258
Query: 114 GADLPSSMKEKAKAE-------TEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSAN 166
P++ KE A T K+ T P P T K+ +P + EP+
Sbjct: 259 ----PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 314
Query: 167 TTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDE-----TDVEGKPSVK-- 219
T PA +P + A ++ ++ + ++ + T E P+
Sbjct: 315 TP---------KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 365
Query: 220 --PAQVKASSVSTKE----SPARKAAPAPGKVGDVTPQVKGGALP--PAKRAKKPEEESE 271
P K + +TKE +P A AP K TP+ P PA K +
Sbjct: 366 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 425
Query: 272 SSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGK---AGAVAS 328
E + + AP T+ + K A + P + +P PAP A
Sbjct: 426 PKEPAPTTTKSAPTTTKEPAPTTTK----SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 481
Query: 329 QTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPR--KGA 386
+ P+E + ++ +E + + + PA + + T + A + P K +P +
Sbjct: 482 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTT--PKEPAPTTPKETAPTTPKKLTPTTPEKL 539
Query: 387 APAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKES 446
AP P K P + A E+ ++ E + A A + K P PA +
Sbjct: 540 APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 599
Query: 447 PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDRE----------ALAAMNAAQ 496
P++ AP P++T P + ++ ++ + + +E + A
Sbjct: 600 PKE-PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 658
Query: 497 VKPLGKSPQV--KPASTMGMGPLG---KGAGPVPPGKVGPATPSAQVGKWEEDSESSSEE 551
P G +P +PA T P KG P + P TP K E ++
Sbjct: 659 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGP 717
Query: 552 SSDSSDGEVPTA---VAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS 608
+S +SD PT AP K KP + + PP V+ ++P
Sbjct: 718 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 777
Query: 609 ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRK 668
+S +ES+ +E P A+ + +P + +T A K TT + K
Sbjct: 778 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA--------------K 823
Query: 669 AGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAAS 728
T ++P + ++++++ E +E ++ A +
Sbjct: 824 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTES-------------------KITATT 864
Query: 729 VPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
V + Q T P T K + + ++ E + E A P
Sbjct: 865 TQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKD-------- 916
Query: 789 QAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVP 848
RA ++K T P K A + K P VR P+ + + +++P
Sbjct: 917 ---------RATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 967
Query: 849 SV---GKAVATAAQAQTGPEEDSGSSEEESDSEEE 880
+ + Q T P + S E + + E
Sbjct: 968 ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSE 1002
Score = 108 bits (271), Expect = 3e-23
Identities = 177/923 (19%), Positives = 308/923 (33%), Gaps = 116/923 (12%)
Query: 336 EEDSESSSEESSDSEEETPAAKAL-----LQAKASGKTSQVGAASAPAKESPRKGAA--- 387
+E + ++ + S+D +E+T +AK AK TS+V A P E+ KG A
Sbjct: 194 KETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTT 253
Query: 388 PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447
P P T P + K + S + +E AP K + P+ A + + +P
Sbjct: 254 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 313
Query: 448 RKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVK 507
PAP PA + + +P +P+ K
Sbjct: 314 TTPKEPAPTTTKEPAPTTTK-----------------------SAPTTPKEPAPTTPK-K 349
Query: 508 PASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPA 567
PA T P P P + P TP +E + ++ +E + ++ P AP
Sbjct: 350 PAPTTPKEP-----APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA----PKKPAPT 400
Query: 568 QEKSLGNILQAKPTSSPAKGPPQKAGPVAV-QVKAEKPMDNSESSEESSDSADSEEAPAA 626
K PA P++ P + P + + ++ +S+ + E AP
Sbjct: 401 TPK------------EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT 448
Query: 627 MTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGT 686
+A P P T P T A P + P K T+P +P T
Sbjct: 449 TKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KEPAPTTPKEPAPTT---T 504
Query: 687 QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGK 746
++PA ++ E + + ++T + + L P + + AP P +
Sbjct: 505 KKPA-PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP-TTPEELAPTTPEE 562
Query: 747 TGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTI 806
PT + A +++ + E A +P + + K A P + KGT
Sbjct: 563 PTPTTPEEPA--PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 620
Query: 807 SAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEE 866
K A K+ +P ++ P ST + + P A T P+E
Sbjct: 621 PTTLK-EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK--------GTAPTTPKE 671
Query: 867 DSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQA 926
+ ++ +E A P G AP + K APT P K P+ +
Sbjct: 672 PAPTTPKEP---------APTTPKG--------TAP---TTLKEPAPTTPKK--PAPKEL 709
Query: 927 GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 986
G +S SD T+ K P +P P P STP
Sbjct: 710 APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTT 769
Query: 987 ARASESTARSSSSESEDEDVIPATQCL--------TPGIRTNVVTMPTAHPRIAPKASMA 1038
+ + +S + + P + L P +T T P K +
Sbjct: 770 TKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 829
Query: 1039 GASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQA 1098
++ E++ + +E T + + AT+ Q TS + T K+ ++
Sbjct: 830 DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF---KITTLKTT 886
Query: 1099 TKAPESSDDSED-SSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDD 1157
T AP+ + + ++ E+ P+ + P P + T A
Sbjct: 887 TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK------PTKAPKKPTS 940
Query: 1158 VVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAG 1217
P + P TP + + P+L+ + ++ + + P
Sbjct: 941 TKKP--KTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAML---QTTTRPNQTPNSKLV 995
Query: 1218 MLSPKTGGKEAASGTTPQKSRKP 1240
++PK+ A G TP +P
Sbjct: 996 EVNPKSEDAGGAEGETPHMLLRP 1018
Score = 105 bits (262), Expect = 3e-22
Identities = 192/1023 (18%), Positives = 354/1023 (34%), Gaps = 115/1023 (11%)
Query: 66 EEDAALQAKKTRVSDP-ISTSESSEEEEEAEAETAKA-TPRLASTNSSVLGADLPSSMKE 123
E + L +V+ P ST++ ++ + TAK PR + +S + ++ +
Sbjct: 128 EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNK 187
Query: 124 KAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFG 183
+ ET++ T N + ++ + T + +T + P
Sbjct: 188 ETTVETKET--------------TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 233
Query: 184 AAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPG 243
AKP + + T T + S P + +++ + + ++ AP
Sbjct: 234 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 293
Query: 244 KVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAA 303
K TP+ P K+P + + ++E AP T+S ++
Sbjct: 294 KSAPTTPKE-----PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE------- 341
Query: 304 SAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAK 363
PA TP K A P A + P+E + ++ E + + +E PA A K
Sbjct: 342 --PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE-PAPTA--PKK 396
Query: 364 ASGKTSQVGAASAPAKESPRKGAAPAP--PGKTGPAVAKAQAGKREEDSQSSSEESDSEE 421
+ T + A + P + +P P+P P + P K+ +E + ++++ + +
Sbjct: 397 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 456
Query: 422 EAPAQA---KPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSS 478
+ P+ +P+ P+ A + P K +P PAP PA +
Sbjct: 457 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK----------- 505
Query: 479 SEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQV 538
KP +P+ +PA T K P P K+ P TP
Sbjct: 506 -------------------KPAPTTPK-EPAPT-----TPKETAPTTPKKLTPTTPEKLA 540
Query: 539 GKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPT-SSPAKGPPQKAGPVAV 597
E ++ E + E PT P + A T PA P++ P
Sbjct: 541 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 600
Query: 598 QVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVA 657
+ A + + + + + PA T + P P T P T A
Sbjct: 601 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 660
Query: 658 PVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPA--EDSSSSEESDSEEEKTGLAVTVGQA 715
P P K T+P +P GT E + ++ + + +E A
Sbjct: 661 PKGTAPTTP-KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE---------LA 710
Query: 716 KSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAA 775
+ KG + P + + TAP P + PT + A + + + SE +
Sbjct: 711 PTTTKGPTSTTSDKPAP-TTPKETAPTTPKEPAPTTPKKPA---PTTPETPPPTTSEVST 766
Query: 776 ASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQ 835
+ + T++ K+ ++ P + P+ K ++P + ++P+ KP +
Sbjct: 767 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE----PGVPTTKTPAATKPEMTTTA 822
Query: 836 NSTVLARGPASVPSVGKAV-ATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTH 894
R + P A + T E+ + S + ++ + T P T
Sbjct: 823 KDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT 882
Query: 895 QIRAALAPAKESPRKGAAPTP-PGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ 953
LAP + +K T K +A + +S +++ + +AP TS +
Sbjct: 883 LKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTK 942
Query: 954 VIKPPLIFVDPNRSPA-----------GPAATPAQAQAASTPRKARASESTARSSSSESE 1002
K P +P P + A+A +T R + S + +SE
Sbjct: 943 KPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSE 1002
Query: 1003 D----EDVIPATQCLTPGIRTNVVTMPTAH-PRIAPKASMAGASSSKESSRISDGKKQEG 1057
D E P L P + VT + PR+ + + S E++ I +GK +G
Sbjct: 1003 DAGGAEGETP-HMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETN-ICNGKPVDG 1060
Query: 1058 PAT 1060
T
Sbjct: 1061 LTT 1063
Score = 38.1 bits (87), Expect = 0.062
Identities = 71/418 (16%), Positives = 129/418 (30%), Gaps = 30/418 (7%)
Query: 1042 SSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKA 1101
++ ++S K P + P+ P S + + ++ + + T
Sbjct: 141 TTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTN 200
Query: 1102 PESSDDSEDSSDSSSGSE--EDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVV 1159
++S D ++ + S+ ++ E A ++ L PTP T E
Sbjct: 201 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT 260
Query: 1160 APSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGML 1219
P + + P TP +++ TPK + + S +P +P
Sbjct: 261 TPKEPASTTPKEP--TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 318
Query: 1220 SPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVV 1279
T KE A TT PK+ A +P P + +
Sbjct: 319 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPK---------------KPAPTTPKEPAPTTP 363
Query: 1280 KVLTELLEQE----RKKVVDTTKESSRKGWESRKRKLSGDQPAARTPR----SKKKKKLG 1331
K T +E K+ TT + + + +PA TP+ + K+
Sbjct: 364 KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 423
Query: 1332 AGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTV 1391
A + + TT+K A S K+ + + A P+E T
Sbjct: 424 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT---TP 480
Query: 1392 EGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1449
+ + PK + +K + A T E+ KK T E+
Sbjct: 481 KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 538
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 104 bits (259), Expect = 7e-22
Identities = 243/1120 (21%), Positives = 385/1120 (34%), Gaps = 163/1120 (14%)
Query: 235 ARKAAPAPGKVGDVTPQVKGGALPP--------------AKRAKKPEEESESSEEGSESE 280
A PA G +TP+ G PP +KP E G+
Sbjct: 12 AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 281 EEAP-------AGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAG 333
E AP AGT S+ AS R AP P K +P P G + T+ G
Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGERAP----PAKNTSPGPVSSPGRASGTTRPG 127
Query: 334 K-PEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAA----- 387
++ S+EE+ + T A K + + + + P+ R+ A
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187
Query: 388 ----PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPA 443
PAP + P G R+ S S+SE S +E A+ +PS R PA
Sbjct: 188 GLPRPAPSARPRPPTE----GPRKSVS-SASEHSTTEPSPAARRRPSAGGGLQR----PA 238
Query: 444 KESPRKGAAP-APPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGK 502
S A P + P ++GP+A R+ + S + L A+ QV P K
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTP--------RAPAHPSQPKPKGLQALRPPQVTPPRK 290
Query: 503 --SPQVKPASTMGMG---PLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSD 557
+P + P S+ + P G A PVPP ATP S
Sbjct: 291 DAAPALGPLSSSPLATPSPSGTKARPVPPPD-NAATPLPAT-------------LPPSPP 336
Query: 558 GEVPTAVAPAQEKSLGNI--LQAKPTSSPAKGPPQKAGP---VAVQVKAEKPMDNSESSE 612
P +AP + ++ L + P + P++ PP P ++ P+ S
Sbjct: 337 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSL- 395
Query: 613 ESSDSADSEEAPAAMTAAQAKPALKIPQTKAC-------PKKTNTTASAKVAPVRVGTQA 665
+S S + +P A+++ QA +L P +A P++T + ++ P +
Sbjct: 396 -TSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDS 454
Query: 666 PRKAGTATSPAGS----------SPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQA 715
P + PA SP + T P + SS + + L + +
Sbjct: 455 PPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLET 514
Query: 716 KS--VGKGLQVKAASV--PVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDS 771
+S LQ AS+ P +L P L + P T E ++
Sbjct: 515 QSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTP-HLETPPCPAPCPLQAPP 573
Query: 772 EEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPV 831
P + +S+ +A PA A +P +G S P + A Q P PP+
Sbjct: 574 SPLTTPPPETPSSIATPPPQAPPALA-SPPLQGLPSPP--LSPLATPPPQAPPXLALPPL 630
Query: 832 RNPQNSTVLAR-GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETL------ 884
+ P + P + PS A A P S ++ A
Sbjct: 631 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 690
Query: 885 --AQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSD 942
+Q PS ++ +P P +A PP P AA + S +S
Sbjct: 691 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPS 750
Query: 943 GEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESE 1002
P V PPL+ P + P P A+ + A P +A + +T + S
Sbjct: 751 ATPPPRV-------PPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSP 803
Query: 1003 DEDVIPATQCLTPGIRTNVVTMPTAHPRIAP--KASMAGASSSKESSRISDGKKQEGPAT 1060
P +P + + T P+ P A + S +S ++ P
Sbjct: 804 PAS-FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP-PTP 861
Query: 1061 QVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEE 1120
D++V + P+ T A G P P + + D + SS ++S EE
Sbjct: 862 GPDTSV-----SGPRLTLALAPG------PPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 910
Query: 1121 ---DGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPA 1177
GP+G +A P P + ++ A + S P L
Sbjct: 911 LRGYDSGPEGGAAA----SPPP---------------DAELAACHPAAWSRGPAPPLAFR 951
Query: 1178 NSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGML----SPKTGGKEAASGTT 1233
+ + + P + L + +G + A P A G L SP T G +AA+G
Sbjct: 952 GAPGAPLPWPPATGPGSADGLCTIYETEGPESATP--APGALDPGPSPGTSGGKAAAGAG 1009
Query: 1234 PQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQ 1273
S + K A + ALQ+++ Q LL + L A+
Sbjct: 1010 AGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAE 1049
Score = 70.5 bits (171), Expect = 1e-11
Identities = 245/1154 (21%), Positives = 371/1154 (32%), Gaps = 146/1154 (12%)
Query: 59 LGRKRKAEE----------DAALQAKKTRVSDPISTSESSEEEEEAEAETA----KATPR 104
+GRK AE ++A +A TR + S + +S E A +P
Sbjct: 53 VGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG 112
Query: 105 LASTNSSVLGADLPSSMKEK----AKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKS 160
S+ G P + +K + ET GK + A SG +P
Sbjct: 113 PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP 172
Query: 161 AEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSV-- 218
+ A + + TE PA A +P ++ SS+ + S++ +PS
Sbjct: 173 SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232
Query: 219 ---KPAQVKASSVSTK-ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSE 274
+PA SS +T SPAR A G P P +A +P + + +
Sbjct: 233 GLQRPASRSLSSSATPLSSPARSGPSARGT--PRAPAHPSQPKPKGLQALRPPQVTPPRK 290
Query: 275 EGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAG- 333
+ + A S A+ +A P P ATP P + T
Sbjct: 291 DAA----PALGPLSSSPLATPSPSGTKARPVP---PPDNAATPLPATLPPSPPLATPLPL 343
Query: 334 KPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGK 393
P S S ++ S TP ++A + + P + P +P+
Sbjct: 344 APPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP 403
Query: 394 TGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP 453
P + S + +P Q + S +P S PA P
Sbjct: 404 PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSP-----SRPASTPPDSPPLQ 458
Query: 454 APPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMG 513
AP + PA+ +Q S SS + +AL+++ SPQ P S++
Sbjct: 459 AP--LSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSL-------ASHSPQA-PLSSLI 508
Query: 514 MGPLGKGAGPVPPGKVGP-----ATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQ 568
M PL + PP P P + ++ + E P AP
Sbjct: 509 MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568
Query: 569 EKSLGNILQAKPTSSPAK--GPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAA 626
++ + L P +P+ PP +A P A P+ S S P A
Sbjct: 569 LQAPPSPLTTPPPETPSSIATPPPQAPPAL----ASPPLQGLPSPPLS---------PLA 615
Query: 627 MTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRV-GTQAPRKAGTATSPAGSSPAVAGG 685
QA P L +P +A P + AS ++P+ QAP A SP +
Sbjct: 616 TPPPQAPPXLALPPLQAPP---SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 672
Query: 686 TQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPG 745
Q P +S S S A QA L VP + P+ P
Sbjct: 673 VQAPFSPPASPPVSPS-------ATPPSQAP---PSLAAPPLQVPPS---PPASPPMSPS 719
Query: 746 KTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGT 805
T P AA P QV S +P+A P
Sbjct: 720 ATPP------------------PQAPPPLAAPPLQVPPS-PPASPPMSPSATPPPRVPPL 760
Query: 806 ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGP-ASVPSVGKAVATAAQAQTGP 864
++AP V + A KPP PQ LA P ++PS + QA P
Sbjct: 761 LAAPPLQVPPSPPASLPMSPLAKPP---PQAPPALATPPLQALPS--PPASFPGQAPFSP 815
Query: 865 EEDSGSSEEESDSEEEAETLA----QVKPSGKTHQIRAALAPAKESPRKGAAPTP-PGKT 919
S + + LA QV PS +P ++PR+ P P +
Sbjct: 816 SASLPMSPLATPPPQAPPVLAAPLLQVPPS-------PPASPTLQAPRRPPTPGPDTSVS 868
Query: 920 GP--SAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 977
GP + A A S S S G A +S+ P + + G AA+P
Sbjct: 869 GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 928
Query: 978 AQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTM-PTAHPRIAPKAS 1036
+ A S A + +P PG + T+ T P A A
Sbjct: 929 DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPA- 987
Query: 1037 MAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQ 1096
GA S S GK G S SP+ + L+ + +
Sbjct: 988 -PGALDPGPSPGTSGGKAAAGAGAGASS-------RSPKQARLGELPLGALQASVVQHLL 1039
Query: 1097 QATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHT---------LVGPTPSRTETLVE 1147
T +++ + S G E G GA++A + L+ P ++
Sbjct: 1040 SRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRASITS 1099
Query: 1148 ETAAESSEDDVVAP 1161
T+ S DDV +P
Sbjct: 1100 VTS--FSPDDVASP 1111
Score = 67.8 bits (164), Expect = 7e-11
Identities = 153/728 (21%), Positives = 249/728 (34%), Gaps = 92/728 (12%)
Query: 430 SGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV-----QVGKQEEDSRS------- 477
+G A + AA AP +PR +P PP PAA +V VG++ R+
Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69
Query: 478 ---SSEESDSDREA-LAAMNAAQVKPL-GKSPQVKPASTMGMGPL---GKGAGPVPPGKV 529
S+ + R A ++ N A P G+ + PA GP+ G+ +G PG +
Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
Query: 530 G------PATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSS 583
G A + GK E + S+ + D PT P+ + +
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189
Query: 584 PAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKA 643
P P + P E P + S+ E S +E +PAA A L+ P +++
Sbjct: 190 PRPAPSARPRP-----PTEGPRKSVSSASEHS---TTEPSPAARRRPSAGGGLQRPASRS 241
Query: 644 CPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQ--RPAEDSSSSEESDS 701
+++A+ +P R G P GT +PA S G Q RP + + +++
Sbjct: 242 ----LSSSATPLSSPARSG---PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA-- 292
Query: 702 EEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQED 761
L + KA VP + LP + P T +
Sbjct: 293 ---APALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLP-PSPPLATPLPLAPPSP 348
Query: 762 SESSEEESDSEEAAASPAQVKTSVKKTQAKANPA----------------AARAPSAKGT 805
S ++ A P+Q S+ +A P+ + +AP +
Sbjct: 349 SAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLA 408
Query: 806 ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE 865
+S+ + + Q + S + R Q S PAS P + P
Sbjct: 409 LSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468
Query: 866 EDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRK--GAAPTPPGKTGPSA 923
+ S ++ + H ++A + A SP+ + PP +T S
Sbjct: 469 LQTSLS----------PAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSL 518
Query: 924 AQAGKQDDSGSSS----EESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQ 979
A Q S + E S P SA + P L +P PA P QA
Sbjct: 519 APPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHL------ETPPCPAPCPLQAP 572
Query: 980 AASTPRKARASESTARSSSSESEDEDVIPATQCL-TPGIRTNVVTMPTAHPRIA--PKAS 1036
+ + S+ + ++ P Q L +P + P A P +A P +
Sbjct: 573 PSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQA 632
Query: 1037 MAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQ 1096
+S S ++ Q A V + P + P S VQA + P P
Sbjct: 633 PPSPPASPPLSPLATPSPQAPNALAVH--LLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 690
Query: 1097 QATKAPES 1104
++AP S
Sbjct: 691 PPSQAPPS 698
>gi|112821681 G protein-regulated inducer of neurite outgrowth 1 [Homo
sapiens]
Length = 1008
Score = 104 bits (259), Expect = 7e-22
Identities = 204/924 (22%), Positives = 331/924 (35%), Gaps = 154/924 (16%)
Query: 234 PARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKA 293
P P G +G + ++ K + P + G ES +P+G
Sbjct: 24 PTAFFCPQDGSLGAGSSAMRDYCPSQQKASPAPPRHTPDQSPGMESRHRSPSGAGEGASC 83
Query: 294 SEKILQVRAASAPA----KGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDS 349
S+ A +P + +P K A T +GKPE S +E S S
Sbjct: 84 SDGPRGSLACPSPTCFSPQESPSKETLEAHGASISGTPEATTSGKPEPVSSVKTEPKS-S 142
Query: 350 EEETPAAKALLQAKASGKTSQVGAASAPAKESP---RKG---------------AAPAPP 391
++ P + K K+S+ +++ KE P RK P P
Sbjct: 143 DDRNP----MFLEKMDFKSSKQADSTSIGKEDPGSSRKADPMFTGKAEPEILGKGDPVAP 198
Query: 392 GKTGPAVAKAQ----AGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASA-PAKES 446
G+ P + + GK + S + +E P + + P KE
Sbjct: 199 GRMDPMTVRKEDLGSLGKVDPLCSSKTYTVSPRKEDPGSLRKVDPVSSDKVDPVFPRKEE 258
Query: 447 PRKGAA--PAPPRKTGPAAAQ----VQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPL 500
PR P K P +A+ V GK+ D S + E++ + + + +P
Sbjct: 259 PRYSGKEHPVSSEKVAPTSAEKVDLVLSGKR--DPGPSGKADPMPLESMDSASTGKTEP- 315
Query: 501 GKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPS-------AQVGKWE------EDSE- 546
G ++ P S+ GP+ G G PG +G P+ A VG E EDS
Sbjct: 316 GLLGKLIPGSSGKNGPVSSGTGA--PGSLGRLDPTCLGMADPASVGNVETVPATKEDSRF 373
Query: 547 ------SSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVK 600
+SS E S TA A SL N+ P SS K P G +
Sbjct: 374 LGKMDPASSGEGRPVSGHTDTTASAKTDLTSLKNV---DPMSS-GKVDPVSLGKMDPMCS 429
Query: 601 AEKPMDNSESSEESSDSADSEEAPAAM--TAAQAKPALKIPQTKACPKKTNTTASAKVAP 658
+ + + +E S +P +++ + + K +K N +S K P
Sbjct: 430 GKPELLSPGQAERVSVGKAGTVSPGKEDPVSSRREDPISAGSRKTSSEKVNPESSGKTNP 489
Query: 659 VRVGTQAPRKAGTATSP-------------------------AGSSPAVAGGTQRP---- 689
V G PR GTA P +G + A G P
Sbjct: 490 VSSGPGDPRSLGTAGPPSAVKAEPATGGKGDPLSSEKAGLVASGKAAPTASGKAEPLAVG 549
Query: 690 AEDSSSSEESDSEEEKTGLAVTVGQAKSV-GKGLQVKAASV-PVK----GSLGQGTAPVL 743
ED S ++D+ G +V++G+ S GK + V + V PV ++ +G L
Sbjct: 550 KEDPVSKGKADAGPSGQGDSVSIGKVVSTPGKTVPVPSGKVDPVSLGKAEAIPEGKVGSL 609
Query: 744 PGKTGPTVTQVKAEKQEDSES-------SEEESDSEEAAASPAQ-----VKTSVKKTQAK 791
P + G VT KA+ + ++ +E + +E AA+P + +K + K
Sbjct: 610 PLEKGSPVTTTKADPRASGKAQPQSGGKAETKLPGQEGAAAPGEAGAVCLKKETPQASEK 669
Query: 792 ANPAAAR----APSAKGTISAPGKVVTAAAQAKQRSPS--KVKPPVRNPQNSTVLARGPA 845
+P + R S KG + GK +A ++ K SPS KV P S + +
Sbjct: 670 VDPGSCRKAEPLASGKGEPVSLGKADSAPSR-KTESPSLGKVVP------LSLEKTKPSS 722
Query: 846 SVPSVGKAVATAAQAQTGPEEDSGSSEEESD--SEEEAETLAQVKPSGKTHQIRAALAPA 903
S + + +A++ G G E +++ S EA +L Q + AA A
Sbjct: 723 SSRQLDRKALGSARSPEGARGSEGRVEPKAEPVSSTEASSLGQ-------KDLEAAGAER 775
Query: 904 KESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVD 963
P + AAP P +T + +A + S D+ +A A + + P +
Sbjct: 776 SPCP-EAAAPPPGPRTRDNFTKAPSWEASAPPPPREDAGTQAGAQACVSVAVSP----MS 830
Query: 964 PNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVT 1023
P G A + A A +P R + ++E T+ + G T
Sbjct: 831 PQDGAGGSAFSFQAAPRAPSPPSRRDAGLQVSLGAAE---------TRSVATGPMTPQAA 881
Query: 1024 MPTAHP--RIAPKASMAGASSSKE 1045
P A P R+ P +++A A + E
Sbjct: 882 APPAFPEVRVRPGSALAAAVAPPE 905
Score = 88.2 bits (217), Expect = 5e-17
Identities = 205/924 (22%), Positives = 329/924 (35%), Gaps = 178/924 (19%)
Query: 171 SETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVST 230
S+ + + P PGM S ++ S + + +S SD P A + S
Sbjct: 48 SQQKASPAPPRHTPDQSPGMESRHRSPSGAGEGASCSDG------PRGSLACPSPTCFSP 101
Query: 231 KESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEES--------------ESSEEG 276
+ESP+++ A G TP+ P + K E +S +SS++
Sbjct: 102 QESPSKETLEAHGASISGTPEATTSGKPEPVSSVKTEPKSSDDRNPMFLEKMDFKSSKQA 161
Query: 277 SESE--EEAPAGTRS-----QVKASEKILQVRAASAPAKGTP------------------ 311
+ +E P +R KA +IL AP + P
Sbjct: 162 DSTSIGKEDPGSSRKADPMFTGKAEPEILGKGDPVAPGRMDPMTVRKEDLGSLGKVDPLC 221
Query: 312 -GKGATPAP----PGKAGAV--ASQTKAG----KPEEDSESSSEESSDSEEETPAAKALL 360
K T +P PG V S K + EE S E SE+ P + +
Sbjct: 222 SSKTYTVSPRKEDPGSLRKVDPVSSDKVDPVFPRKEEPRYSGKEHPVSSEKVAPTSAEKV 281
Query: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPA----VAKAQAGKREEDSQSSSEE 416
SGK S A P + A GKT P + +GK S +
Sbjct: 282 DLVLSGKRDP--GPSGKADPMPLESMDSASTGKTEPGLLGKLIPGSSGKNGPVSSGTGAP 339
Query: 417 SDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSR 476
P + A + PA + + P +G + + D+
Sbjct: 340 GSLGRLDPTCLGMADPASVGNVETVPATKEDSRFLGKMDPASSG----EGRPVSGHTDTT 395
Query: 477 SSSEESDSDREALAAMNAAQVKP--LGK-------SPQVKPASTMGMGPLGKGAGPVPPG 527
+S++ + + + M++ +V P LGK P++ +GK AG V PG
Sbjct: 396 ASAKTDLTSLKNVDPMSSGKVDPVSLGKMDPMCSGKPELLSPGQAERVSVGK-AGTVSPG 454
Query: 528 KVGPATPSAQVGKWEEDSESSSEESSDSSDGEV-PTAVAPAQEKSLG-----NILQAKPT 581
K P + + ++SSE+ + S G+ P + P +SLG + ++A+P
Sbjct: 455 KEDPVSSRREDPISAGSRKTSSEKVNPESSGKTNPVSSGPGDPRSLGTAGPPSAVKAEPA 514
Query: 582 SSPAKGPP---QKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKP---- 634
+ KG P +KAG VA A +S ++ A +E P + A A P
Sbjct: 515 TG-GKGDPLSSEKAGLVASGKAA------PTASGKAEPLAVGKEDPVSKGKADAGPSGQG 567
Query: 635 -ALKIPQTKACPKKTNTTASAKVAPVRVG-----------------------TQA-PRKA 669
++ I + + P KT S KV PV +G T+A PR +
Sbjct: 568 DSVSIGKVVSTPGKTVPVPSGKVDPVSLGKAEAIPEGKVGSLPLEKGSPVTTTKADPRAS 627
Query: 670 GTATSPAG-------------SSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAK 716
G A +G ++P AG E +SE+ D + + G+ +
Sbjct: 628 GKAQPQSGGKAETKLPGQEGAAAPGEAGAVCLKKETPQASEKVDPGSCRKAEPLASGKGE 687
Query: 717 SVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEE-ESDSEEAA 775
V G KA S P + + V+P + EK + S SS + + + +A
Sbjct: 688 PVSLG---KADSAPSRKTESPSLGKVVP---------LSLEKTKPSSSSRQLDRKALGSA 735
Query: 776 ASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQ 835
SP + S + + KA P ++ S+ G K + AA + P PP
Sbjct: 736 RSPEGARGSEGRVEPKAEPVSSTEASSLGQ-----KDLEAAGAERSPCPEAAAPP----- 785
Query: 836 NSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQ 895
GP + + KA + A A P ED+G + + +A V P
Sbjct: 786 ------PGPRTRDNFTKAPSWEASAPPPPREDAG-----TQAGAQACVSVAVSPMSPQDG 834
Query: 896 IRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVI 955
+ + +PR AP+P PS AG Q G++ S + G P +A
Sbjct: 835 AGGSAFSFQAAPR---APSP-----PSRRDAGLQVSLGAAETRSVATG--PMTPQAAAPP 884
Query: 956 KPPLIFVDPNRSPAGPAATPAQAQ 979
P + V P + A A P A+
Sbjct: 885 AFPEVRVRPGSALAAAVAPPEPAE 908
Score = 44.3 bits (103), Expect = 9e-04
Identities = 90/409 (22%), Positives = 143/409 (34%), Gaps = 79/409 (19%)
Query: 91 EEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVAN 150
E+ + T KA PR + G P S KAET+ G+ G + P G+ A
Sbjct: 612 EKGSPVTTTKADPRAS-------GKAQPQS---GGKAETKLPGQEGAAAP----GEAGAV 657
Query: 151 LLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADS------------ 198
L ++P+ S + + +E G K VS G+ADS
Sbjct: 658 CLKKETPQASEKVDPGSCRKAEPLASG---------KGEPVSLGKADSAPSRKTESPSLG 708
Query: 199 -----SSEDTSSSSDETDVEGKP------------SVKPAQVKASSVSTKESPARKAAPA 241
S E T SS ++ K S + KA VS+ E+ +
Sbjct: 709 KVVPLSLEKTKPSSSSRQLDRKALGSARSPEGARGSEGRVEPKAEPVSSTEASSLGQKDL 768
Query: 242 PGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVR 301
+ +P + A PP R + ++ S E + AGT++ +A V
Sbjct: 769 EAAGAERSPCPEAAAPPPGPRTRDNFTKAPSWEASAPPPPREDAGTQAGAQAC-----VS 823
Query: 302 AASAPAKGTPGKGAT----------PAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEE 351
A +P G G + P+PP + A Q G +E+ S +
Sbjct: 824 VAVSPMSPQDGAGGSAFSFQAAPRAPSPPSRRDA-GLQVSLGA----AETRSVATGPMTP 878
Query: 352 ETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKT----GPAVAKAQAGKRE 407
+ A A + + ++ A + P P + + G T G A+ G
Sbjct: 879 QAAAPPAFPEVRVRPGSALAAAVAPPEPAEPVRDVSWDEKGMTWEVYGAAMEVEVLGMAI 938
Query: 408 EDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPP 456
+ E + APA P+ +A R+ S + +P GAA PP
Sbjct: 939 QKHLERQIEEHGRQGAPA-PPPAARAGPGRSGS--VRTAPPDGAAKRPP 984
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 103 bits (256), Expect = 2e-21
Identities = 269/1310 (20%), Positives = 436/1310 (33%), Gaps = 226/1310 (17%)
Query: 55 QTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVL- 113
+T+ G K+ + ++ P ST+ +E + + ST++++
Sbjct: 298 RTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPG-----STDTTLSP 352
Query: 114 GADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLV--S 171
G PSS+ ++ G T + T T + LL +P S+ S +TTL S
Sbjct: 353 GTTTPSSLGPESTTFHSSPGYTKTTRLPDNT--TTSGLLEASTPVHSSTGSPHTTLSPSS 410
Query: 172 ETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTK 231
T EG F + S + ++S S T PS P S+ ST
Sbjct: 411 STTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLS---TTYHSSPSSTPT-THFSASSTT 466
Query: 232 ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESS---EEGSESEEEAPAGTR 288
+ ++ P +P PPA+ A E ++ GS P +
Sbjct: 467 LGHSEESTPVHS-----SPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESST 521
Query: 289 SQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSD 348
+ + E + + TP A A ++ S + + S E S
Sbjct: 522 TSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESK 581
Query: 349 SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGK-TGPAVAKAQ----A 403
+ +P A A A S + S P+ S A PG T P +++ +
Sbjct: 582 ASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYS 641
Query: 404 GKREEDS----QSSSEESDSEEEAPAQAKPSG----KAPQVRAASAPAKESPRKGAAPAP 455
R D+ S + SEE + ++P P ++ES ++P P
Sbjct: 642 SPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGP 701
Query: 456 PRKT----GPAAAQVQVGKQEEDSRSSSEES---DSDREALAAMNAAQ------------ 496
T A+ + SR S E+ + A + A+
Sbjct: 702 TDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTT 761
Query: 497 VKPLGKSPQVKPASTMGMGPLGKGAGPVPP----GKVGPATPS----AQVGKWEEDSESS 548
+ P G + + ++T P K P PP V P+T S + + + S+
Sbjct: 762 LSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARST 821
Query: 549 S----EESS--DSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAE 602
+ EES+ SS G T P + + G + TS + + P E
Sbjct: 822 TSGLVEESTTYHSSPGSTQTMHFPESDTTSGR-GEESTTSHSSTTHTISSAPSTTSALVE 880
Query: 603 KPMDNSES---------SEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTAS 653
+P S + S+ S SEE+ A+ ++ A + +P + +
Sbjct: 881 EPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT 940
Query: 654 AKVAPVRVGTQAPRKAGTATSPA--------GSSPAVAGGTQRPAEDSSS--SEESDSEE 703
+ ++ + T A G+ T+P SSP T PA +SS SEES +
Sbjct: 941 SPISSGSMETTA--LPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSR 998
Query: 704 EKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSE 763
+ G T S + S S G +LP T + ++S
Sbjct: 999 SRPGSTHTTAFPDSTTTP-GLSRHSTTSHSSPGSTDTTLLPAST------TTSGPSQEST 1051
Query: 764 SSEEESDSEEAAASP----------------------------------------AQVKT 783
+S S S + A SP +V +
Sbjct: 1052 TSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHS 1111
Query: 784 SVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARG 843
S + +PA++ +P +G S + A+ PS PV + ST R
Sbjct: 1112 STGSPRTTLSPASSTSPGLQGE-STAFQTHPASTHTTPSPPSTATAPV---EESTTYHRS 1167
Query: 844 PASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPA 903
P S P+ A+ +G E S D+ + A SG+ + ++P
Sbjct: 1168 PGSTPTTH---FPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG 1224
Query: 904 KESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVD 963
P T P ++A + SS S + +PA++TS V + +
Sbjct: 1225 STE----ITTLPGSTTTPGLSEA---STTFYSSPRSPTTTLSPASMTSLGVGE------E 1271
Query: 964 PNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVI-------------PAT 1010
S + P +T + AST + EST SSS E + P T
Sbjct: 1272 STTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTT 1331
Query: 1011 ---------------QCLTPGIRTNVVTMP-------TAHPRIAPKASMAGASSSKESSR 1048
T G+ P T P A + S++ SS
Sbjct: 1332 FHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS 1391
Query: 1049 ISDGKKQEGPATQVDSAVG---------------TLPATSPQSTSVQAKGTNKLRKPKLP 1093
S G K + VG TLP SP + S+ K T P+ P
Sbjct: 1392 GSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPG-SPTTPSLSEKSTTFYTSPRSP 1450
Query: 1094 EVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAES 1153
+ AT +P ++ S S +SS+ + G S HT P + T L +E
Sbjct: 1451 D---ATLSPATTTSSGVSEESSTSHSQPG-------STHTTAFPDSTTTSDLSQEPTTSH 1500
Query: 1154 SEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDD 1203
S SQ ++PG T A+S ++T SSP + T DD
Sbjct: 1501 S-------SQGSTEATLSPGSTTASSLGQQST-TFHSSPGDTETTLLPDD 1542
Score = 101 bits (251), Expect = 6e-21
Identities = 283/1378 (20%), Positives = 449/1378 (32%), Gaps = 175/1378 (12%)
Query: 76 TRVSDPISTSESSEEEEEAEAE--TAKATPRLASTNSSVLGADLPSSMKEKAKAETE--- 130
T D +TS+ S+E + + + +AT ST +S LG + ET
Sbjct: 1481 TAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP 1540
Query: 131 ----KAGKTGNSMP-HPATGKTVANLLSGKSPRKSAEPSANT--TLVSETEEEGSVPAFG 183
+G S P H +TG L S + + T + S ++ S P
Sbjct: 1541 DDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTT 1600
Query: 184 AA---------AKPGMVSAGQADSSSEDTSSSSDETDVEGKPSV---------------- 218
AA ++P +SS S + T V P
Sbjct: 1601 AAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLV 1660
Query: 219 -KPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGS 277
+P SS ST+ + + G T P + S SEE +
Sbjct: 1661 GEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEEST 1720
Query: 278 ESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEE 337
S + + S + V S + +PG T PG A + PE
Sbjct: 1721 TSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLG-----PES 1775
Query: 338 DSESSSEESSDSE--EETPAAKALLQAKA---------------SGKTSQVGAASAPAKE 380
+ SS S+++ + A LL+A +G T++ G ++
Sbjct: 1776 TTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSW 1835
Query: 381 SPRKGAAPAPPGKTGPAVAKAQAGKREEDSQ-------SSSEESDSEEEAPAQAKPSGKA 433
K PAPP T V + S SS+ SEE + P A
Sbjct: 1836 PSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 1895
Query: 434 PQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMN 493
+PA+ + + + P + Q + + SEES + + +
Sbjct: 1896 ----TTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTT--H 1949
Query: 494 AAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESS 553
P S V+ ++ P P S G+ EE + S S + +
Sbjct: 1950 TISSPPSTTSALVEEPTSYHSSPGSTATTHFPDS-------STTSGRSEESTASHSSQDA 2002
Query: 554 DSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEE 613
T V PA +S ++L + T+SP + + + S +
Sbjct: 2003 TG------TIVLPA--RSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHS 2054
Query: 614 SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT 673
S S + +PA+ T++ ++ P T+TTA T P + +T
Sbjct: 2055 SPRSPATTLSPASTTSSGVSEESTTSHSR--PGSTHTTAFPD------STTTPGLSRHST 2106
Query: 674 SPAGSSPAVAGGTQRPAEDSSS-----SEESDSEEEKTGLAVTVGQAKSVGKGLQVKAAS 728
+ + SSP T PA ++S S S S T A++ G ++ G + S
Sbjct: 2107 T-SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQE----S 2161
Query: 729 VPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
S G + P T + + + S S + S ++ SP S T
Sbjct: 2162 TTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGES---T 2218
Query: 789 QAKANPAAARA-PSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASV 847
+ +PA+ PS T +AP + T RSP P P +ST S
Sbjct: 2219 AFQTHPASTHTTPSPPSTATAPVEESTTY----HRSPGST-PTTHFPASSTTSGHSEKST 2273
Query: 848 -----PSVGKAVATAAQAQTGPEEDSGSSEEESDSEE--------------EAETLAQVK 888
P ++A + T +S +S S E EA T
Sbjct: 2274 IFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSS 2333
Query: 889 PSGKTHQIR-AALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPA 947
P T + A++ + + PG T + + A G S E + +P
Sbjct: 2334 PRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTP-GLSEESTTVYSSSPG 2392
Query: 948 AVTSAQVIKPPLIFV---DPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDE 1004
+ + + P V +P + PA+T + ESTA S S
Sbjct: 2393 STETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQT 2452
Query: 1005 DVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDS 1064
+PAT T + T P++ S A +++S G+ + +
Sbjct: 2453 G-LPAT-LTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLV-----GESTPSRLSPSST 2505
Query: 1065 AVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSS--GSEE-- 1120
TLP SP + S+ K T P+ P+ + SS SE+SS S S GS
Sbjct: 2506 ETTTLPG-SPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTT 2564
Query: 1121 ---DGEGPQGAKSAHTLVGPTPSRTETLV----EETAAESSEDDVVAPSQSLLSGYMTPG 1173
D G T +P T+T + T+ S E S ++PG
Sbjct: 2565 AFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPG 2624
Query: 1174 LTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTT 1233
T A S ++T S S +TL PD + +A+ + TG +
Sbjct: 2625 STTALSFGQESTTFHSSPGSTHTTLF----PDSTTSSGIVEASTRVHSSTGSPRTT--LS 2678
Query: 1234 PQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKV 1293
P S P + T ++ T P P + A + V+ T
Sbjct: 2679 PASSTSPGLQGESTTFQTHPASTHTT------PSPPSTA---TAPVEESTTYHRSPGSTP 2729
Query: 1294 VDTTKESSRKGWESRKRKLSGDQPAAR--TPRSKKKKKLGAGEGGEASVSPEKTSTTS 1349
SS S K + P A TP S G GE + +SP T T+
Sbjct: 2730 TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITT 2787
Score = 100 bits (250), Expect = 8e-21
Identities = 247/1209 (20%), Positives = 415/1209 (34%), Gaps = 161/1209 (13%)
Query: 81 PISTSESSEEEEEAEAETAKATPR--LASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138
P ST+ S E ++ +PR L+ +S+ G S+ + A T ++
Sbjct: 3734 PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPST 3793
Query: 139 MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSE--TEEEGSVPAFGAAAKPG-MVSAGQ 195
P T + G +P S+ T+ SE T S A G ++G+
Sbjct: 3794 ATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGR 3853
Query: 196 ADSSSEDTSSSSDETDVEGKPSVKPAQVKASSV--STKESPARKAAPAPGK---VGD--V 248
+S++ S S E + P +AS+ S+ SP +PA VG+
Sbjct: 3854 GESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEEST 3913
Query: 249 TPQVKGGAL-----PPAKRAKKPEEESE---SSEEGSESEEEAPAGTRSQVKASEKI-LQ 299
T + + G+ P + EES SS GS P T + V+ E
Sbjct: 3914 TSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFH 3973
Query: 300 VRAASAPA----KGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPA 355
R AS + + G T G+ AS T+ G P + + E S + +
Sbjct: 3974 SRPASTHTTLFTEDSTTSGLTEESTAFPGSPAS-TQTGLPATLTTADLGEESTTFPSSSG 4032
Query: 356 AKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSE 415
+ + A TS + S P++ SP PG + S SE
Sbjct: 4033 STGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSP--------------TTPSLSE 4078
Query: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDS 475
+S + +P ++ + +P +S ++ES + P T + G +E +
Sbjct: 4079 KSTTFYTSP-RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPT 4137
Query: 476 RSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPS 535
S S + + EA + + LG+ +S + G V +TP+
Sbjct: 4138 TSHSSQGST--EATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPT 4195
Query: 536 AQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLG-----NILQAKPTSSPAKGPPQ 590
SS G + T + PA S G Q+ P+SS P
Sbjct: 4196 ------------------HSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPP 4237
Query: 591 KAGPVAVQVKA---EKPMDNSES--SEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP 645
V V+V +P + S S+ SEE+ ++ A P A
Sbjct: 4238 STTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSAT- 4296
Query: 646 KKTNTTASAKVAPVRVGTQAPRKAGTATSPAG---------SSPAVAGGTQRPAEDSSS- 695
+ +P+ G+ +T+ AG SSP T PA +SS
Sbjct: 4297 --SVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSG 4354
Query: 696 -SEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQV 754
SEES + + G T S V S S G + PG T +
Sbjct: 4355 VSEESTTSHSRPGSMHTTAFPSSTTMP-GVSQESTASHSSPGSTDTTLSPGSTTASSLGP 4413
Query: 755 KAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT 814
++ S S E + + + ++ S + +P +P+ T
Sbjct: 4414 ESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQ 4473
Query: 815 AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE 874
+ +K +P+ + ST P+S P+ + ++ ++ EE
Sbjct: 4474 SWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRS----------EE 4523
Query: 875 SDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGS 934
S + + PS PA+ + + + P + Q +S +
Sbjct: 4524 STTVHSSPVATATTPS-----------PARSTTSGLVEESTTYHSSPGSTQTMHFPESNT 4572
Query: 935 SS---EESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASE 991
+S EES + + S+ + +P + P +T S+ R+ E
Sbjct: 4573 TSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE 4632
Query: 992 STARSSSSESEDEDVIPA------------TQCLTPG-IRTNVVTMPTAHPRIAPKASMA 1038
STA SS ++ V+PA T ++ G + T + T P ++ K++
Sbjct: 4633 STASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTF 4692
Query: 1039 GASSSK------ESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKL 1092
+S S +S + G+ +E T S V T SP ++
Sbjct: 4693 HSSPSSTPTTHFSASSTTLGRSEES-TTVHSSPVATATTPSPARSTTSGLVEESTAYHSS 4751
Query: 1093 PEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAE 1152
P Q PESS S S +S + + + HT+ P PS T LVEE +
Sbjct: 4752 PGSTQTMHFPESSTASGRSEESRTSH---------SSTTHTISSP-PSTTSALVEEPTSY 4801
Query: 1153 SSEDDVVA----PSQSLLSGYM-----------TPGLTP------ANSQASKATPKLDSS 1191
S +A P S SG T G+TP + + +++T S
Sbjct: 4802 HSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISP 4861
Query: 1192 PSVSSTLAA 1200
S+ +TLA+
Sbjct: 4862 GSMETTLAS 4870
Score = 98.6 bits (244), Expect = 4e-20
Identities = 281/1345 (20%), Positives = 446/1345 (33%), Gaps = 201/1345 (14%)
Query: 81 PISTSESSEEEEEAEAETAKATPR--LASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138
P ST+ S E ++ +PR L+ +S+ G S+ + A T ++
Sbjct: 1094 PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPST 1153
Query: 139 MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSE--TEEEGSVPAFGAAAKPG-MVSAGQ 195
P T + G +P S+ T+ SE T S A G ++G+
Sbjct: 1154 ATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGR 1213
Query: 196 ADSSSEDTSSSSDETDVEGKPSVKPAQVKASSV--STKESPARKAAPAPGK---VGD--V 248
+S++ S S E + P +AS+ S+ SP +PA VG+
Sbjct: 1214 GESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEEST 1273
Query: 249 TPQVKGGAL-----PPAKRAKKPEEESE---SSEEGSESEEEAPAGTRSQVKASEKI-LQ 299
T + + G+ P + EES SS GS P T + V E
Sbjct: 1274 TSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFH 1333
Query: 300 VRAASAPA----KGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPA 355
R AS + + G T G+ AS T+ G P + + E S + +
Sbjct: 1334 SRPASTHTTLFTEDSTTSGLTEESTAFPGSPAS-TQTGLPATLTTADLGEESTTFPSSSG 1392
Query: 356 AKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSE 415
+ + A TS + S P++ SP PG + S SE
Sbjct: 1393 STGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSP--------------TTPSLSE 1438
Query: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDS 475
+S + +P ++ + +P +S ++ES + P T + +E +
Sbjct: 1439 KSTTFYTSP-RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPT 1497
Query: 476 RSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPS 535
S S + + EA + + LG+ +S + G V +TP+
Sbjct: 1498 TSHSSQGST--EATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPT 1555
Query: 536 AQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLG-----NILQAKPTSSPAKGPPQ 590
SS G + T + PA S G Q+ P+SS P
Sbjct: 1556 ------------------HSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPP 1597
Query: 591 --KAGPVAVQVKAEKPMDNSESSEESSDSAD---SEEAPAAMTAAQAKPALKIPQTKACP 645
A PV V ++ ++ S+ S SEE+ ++ A P A
Sbjct: 1598 GTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSAT- 1656
Query: 646 KKTNTTASAKVAPVRVGTQAPRKAGTATSPAG---------SSPAVAGGTQRPAEDSSS- 695
+ +P+ G+ +T+ AG SSP T PA +SS
Sbjct: 1657 --SVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSG 1714
Query: 696 -SEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKT------- 747
SEES + + G T S V S S G + PG T
Sbjct: 1715 VSEESTTSHSRPGSTHTTAFPGSTTMP-GVSQESTASHSSPGSTDTTLSPGSTTASSLGP 1773
Query: 748 ---------GPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAAR 798
G T T + + S E + + SP + T + +
Sbjct: 1774 ESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQ 1833
Query: 799 A-PSAKGTISAPGKVVTAAAQ---AKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAV 854
+ PS+K T+ AP +A + SPS P +ST L R S V
Sbjct: 1834 SWPSSKDTMPAPPTTTSAFVELSTTSHGSPSST-PTTHFSASSTTLGRSEESTTVHSSPV 1892
Query: 855 ATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT 914
ATA SG EE + A +
Sbjct: 1893 ATATTPSPARSTTSGLVEEST-----------------------------------AYHS 1917
Query: 915 PPGKTGP-----SAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPA 969
PG T S+ +G+ ++S +S + +P + TSA V +P P
Sbjct: 1918 SPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSP----- 1972
Query: 970 GPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPA---TQCLTPGIRTNVVTMPT 1026
G AT +++T R+ ESTA SS ++ V+PA T L T+ ++ +
Sbjct: 1973 GSTATTHFPDSSTT--SGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGS 2030
Query: 1027 AHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNK 1086
P ++ S K ++ S + PAT + A T S +ST+ ++
Sbjct: 2031 METTALPGSTTTPGLSEKSTTFHSSPRS---PATTLSPASTTSSGVSEESTTSHSR---- 2083
Query: 1087 LRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLV 1146
P T P+S+ S S++ +H+ G T +
Sbjct: 2084 ------PGSTHTTAFPDSTTTPGLSRHSTT--------------SHSSPGSTDTTLLPAS 2123
Query: 1147 EETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDG 1206
T+ S E S ++PG T A S ++T S S +TL PD
Sbjct: 2124 TTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLF----PDS 2179
Query: 1207 KQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQP 1266
+ +A+ + TG +P S P + T ++ T P
Sbjct: 2180 TTSSGIVEASTRVHSSTGSPRTT--LSPASSTSPGLQGESTAFQTHPASTHTT------P 2231
Query: 1267 WPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAAR--TPRS 1324
P + A + V+ T SS S K + P A TP S
Sbjct: 2232 SPPSTA---TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSS 2288
Query: 1325 KKKKKLGAGEGGEASVSPEKTSTTS 1349
G GE + +SP T T+
Sbjct: 2289 AHSTTSGRGESTTSRISPGSTEITT 2313
Score = 98.2 bits (243), Expect = 5e-20
Identities = 255/1275 (20%), Positives = 434/1275 (34%), Gaps = 165/1275 (12%)
Query: 81 PISTSESSEEEEEAEAETAKATPR--LASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138
P ST+ S E ++ +PR L+ +S+ G S+ + A T ++
Sbjct: 2651 PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPST 2710
Query: 139 MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSE--TEEEGSVPAFGAAAKPG-MVSAGQ 195
P T + G +P S+ T+ SE T S A G ++G+
Sbjct: 2711 ATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGR 2770
Query: 196 ADSSSEDTSSSSDETDVEGKPSVKPAQVKASSV--STKESPARKAAPAPGK---VGD--V 248
+S++ S S E + P +AS+ S+ SP +PA VG+
Sbjct: 2771 GESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEEST 2830
Query: 249 TPQVKGGAL-----PPAKRAKKPEEESE---SSEEGSESEEEAPAGTRSQVKASEKI-LQ 299
T + + G+ P + EES SS GS P T + V+ E
Sbjct: 2831 TSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFH 2890
Query: 300 VRAASAPA----KGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPA 355
R AS + + G T G+ AS T+ G P + + E S + +
Sbjct: 2891 SRPASTHTTLFTEDSTTSGLTEESTAFPGSPAS-TQTGLPATLTTADLGEESTTFPSSSG 2949
Query: 356 AKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSE 415
+ + A TS + S P++ SP PG + S SE
Sbjct: 2950 STGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSP--------------TTPSLSE 2995
Query: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDS 475
+S + +P ++ + +P +S ++ES + P T + G +E +
Sbjct: 2996 KSTTFYTSP-RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPT 3054
Query: 476 RSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPS 535
S S + + EA + + LG+ +S + G V +TP+
Sbjct: 3055 ASHSSQGST--EATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPT 3112
Query: 536 AQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLG-----NILQAKPTSSPAKGPPQ 590
SS G + T + PA S G Q+ P+SS P
Sbjct: 3113 ------------------HSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPP 3154
Query: 591 --KAGPVAVQVKAEKPMDNSESSEESSDSAD---SEEAPAAMTAAQAKPALKIPQTKACP 645
A PV V ++ ++ S+ S SEE+ ++ A P A
Sbjct: 3155 GTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSAT- 3213
Query: 646 KKTNTTASAKVAPVRVGTQAPRKAGTATSPAG---------SSPAVAGGTQRPAEDSSS- 695
+ +P+ G+ +T+ AG SSP T PA +SS
Sbjct: 3214 --SVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSG 3271
Query: 696 -SEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQV 754
SEES + + G T S V S S G + PG T +
Sbjct: 3272 VSEESTTSHSRPGSTHTTAFPGSTTMP-GVSQESTASHSSPGSTDTTLSPGSTTASSLGP 3330
Query: 755 KAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT 814
++ S E + + + ++ S + +P +P+ T
Sbjct: 3331 ESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQ 3390
Query: 815 AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE 874
+ +K +P+ + ST P+S P+ + ++ ++ EE
Sbjct: 3391 SWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRS----------EE 3440
Query: 875 SDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQA---GKQDD 931
S + + PS PA+ + + + P + Q + D
Sbjct: 3441 STTVHSSPVATATTPS-----------PARSTTSGLVEESTTYHSSPGSTQTMHFPESDT 3489
Query: 932 SGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASE 991
+ EES + + S+ + +P + P +T S+ R+ E
Sbjct: 3490 TSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE 3549
Query: 992 STARSSSSESEDEDVIPA------------TQCLTPG-IRTNVVTMPTAHPRIAPKAS-- 1036
STA SS ++ V+PA T ++ G + T + T P ++ K++
Sbjct: 3550 STASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTF 3609
Query: 1037 ----MAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATS-PQSTSVQAKGTNKLRKPK 1091
+ A++ +S S G +E +T S G+ T+ P ST+ +
Sbjct: 3610 HSSPRSPATTLSPASTTSSGVSEE--STTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHS 3667
Query: 1092 LPEVQQATKAPESSDDSEDS-----SDSSSGSEEDGEGP----------------QGAKS 1130
P T P S+ S S S SSSGS + P S
Sbjct: 3668 SPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGS 3727
Query: 1131 AHTLVGPTPSRTETLVEET----AAESSEDDVVAPSQSL---LSGYMTPGLT-PANSQAS 1182
HT + P + + +VE + ++ S ++P+ S L G T T PA++ +
Sbjct: 3728 THTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTT 3787
Query: 1183 KATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQA--AGMLSPKT--GGKEAASGTTPQKSR 1238
+ P ++P ST + P + +G T ASGTTP +
Sbjct: 3788 PSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAH 3847
Query: 1239 KPKKGAGNPQASTLA 1253
G G S ++
Sbjct: 3848 STTSGRGESTTSRIS 3862
Score = 96.3 bits (238), Expect = 2e-19
Identities = 269/1307 (20%), Positives = 421/1307 (32%), Gaps = 222/1307 (16%)
Query: 79 SDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138
S + SE S + T A S S ++G S + + TE G++
Sbjct: 1626 STTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPI---SSGSTETTALPGST 1682
Query: 139 MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA---AKPGMVSAGQ 195
+ K+ S +SP + P++ T+ E S G+ A PG +
Sbjct: 1683 TTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG 1742
Query: 196 ADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGG 255
S + SS TD ++ P ASS+ + + + PG
Sbjct: 1743 VSQESTASHSSPGSTDT----TLSPGSTTASSLGPESTTFHSS---PGSTETTL------ 1789
Query: 256 ALPPAKRAKKPEEESES--SEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGK 313
LP A E S S GS +PAG+ ++ S S P+ K
Sbjct: 1790 -LPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTF-----QSWPSS----K 1839
Query: 314 GATPAPPGKAGAVA--SQTKAGKPEEDSESSSEESSDS---EEETPAAKALLQAKASGKT 368
PAPP A S T G P + SS + EE+ + A A+ +
Sbjct: 1840 DTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPS 1899
Query: 369 SQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAK 428
S +ES ++P + +G+ EE S S + + P+
Sbjct: 1900 PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPS--- 1956
Query: 429 PSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREA 488
SA +E ++P T + G+ EE + S S + +
Sbjct: 1957 ---------TTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIV 2007
Query: 489 LAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPG--------KVGPATPSAQVGK 540
L A + V LG+S P S+ M PG P +P+ +
Sbjct: 2008 LPARSTTSVL-LGEST-TSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSP 2065
Query: 541 WEEDSESSSEES--SDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQ 598
S SEES S S G T P + G L T+S + +
Sbjct: 2066 ASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPG--LSRHSTTSHSSPGSTDTTLLPAS 2123
Query: 599 VKAEKPMDNSESSEESSDSADSEEAPAAMTAAQ--------------------------- 631
P S +S S S D+ +P + TA
Sbjct: 2124 TTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSS 2183
Query: 632 --AKPALKIPQTKACPKKTNTTASAKVAPVRVGTQA--PRKAGTATSPAGSSPAVAGGTQ 687
+ + ++ + P+ T + AS+ ++ + A A T T+P+ S A A
Sbjct: 2184 GIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATA---- 2239
Query: 688 RPAEDSSSSEESDSEEEKTGLAV-----------TVGQAKSVGKGLQVKAASVPVKGSLG 736
P E+S++ S T T+ + G +A G
Sbjct: 2240 -PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGE 2298
Query: 737 QGTAPVLPGKT------GPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQA 790
T+ + PG T G T T +E SS + + AS + + T +
Sbjct: 2299 STTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTS 2358
Query: 791 KANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSV 850
++ P + + + + + PG + + SP + V P+ T RG
Sbjct: 2359 RSQPGSTHSTVSPASTTTPG-LSEESTTVYSSSPGSTETTVF-PRTPTTSVRGEEPTTFH 2416
Query: 851 GKAVATAAQAQTGPEEDSGSSEEES--------------------DSEEEAETLAQVKPS 890
+ +T T SG +EE + D EE+ T S
Sbjct: 2417 SRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGS 2476
Query: 891 ---------GKTHQIRAALAPAKESPRKGAAPTPPGK--------------TGPSAAQA- 926
T + P++ SP T PG T P + A
Sbjct: 2477 TGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 2536
Query: 927 ---GKQDDSGSSSEESDSDGEAPAAVTSA--QVIKPPLIFVDPNRSPAGPAATPAQAQAA 981
SG S E S S + + T+A P + S + P +T A
Sbjct: 2537 LSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 2596
Query: 982 STPRKARASESTARSSSSESEDEDVIP-ATQCLTPGIRTNVV------TMPTAHPRIAPK 1034
ST + EST SS S D + P +T L+ G + T T P
Sbjct: 2597 STTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTS 2656
Query: 1035 ASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPE 1094
+ + AS+ SS S P T + A T P +ST+ Q + P P
Sbjct: 2657 SGIVEASTRVHSSTGS-------PRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPS 2709
Query: 1095 VQQA-----------------TKAPESSDDSEDSSDSS---SGSEEDGEGPQGAKSAHTL 1134
A T P SS S S S+ S + G P A S
Sbjct: 2710 TATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHST--- 2766
Query: 1135 VGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANS--QASKATPKLDSSP 1192
T R E+ + S+E + S + TPGL+ A++ +S +P SP
Sbjct: 2767 ---TSGRGESTTSRISPGSTEITTLPGSTT------TPGLSEASTTFYSSPRSPTTTLSP 2817
Query: 1193 SVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRK 1239
+ ++L ++ ++P +SP AS TTP S +
Sbjct: 2818 ASMTSLGVGEE-STTSRSQPGSTHSTVSP-------ASTTTPGLSEE 2856
Score = 89.4 bits (220), Expect = 2e-17
Identities = 235/1175 (20%), Positives = 390/1175 (33%), Gaps = 246/1175 (20%)
Query: 75 KTRVSDPISTSESSEEEEEAEAETAKATPRLA---STNSSVLGADLPSSMKEKAKAETEK 131
+T + ++T++ EE + + +L+ ST S ++G PS + + + TE
Sbjct: 4008 QTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRL---SPSSTET 4064
Query: 132 AGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMV 191
G+ + K+ S +SP + P+ TT S EE S + ++PG
Sbjct: 4065 TTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPA--TTTSSGVSEESST----SHSQPG-- 4116
Query: 192 SAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQ 251
S T++ D T G S +P +S ST+ A +PG
Sbjct: 4117 --------STHTTAFPDSTTTSGL-SQEPTTSHSSQGSTE------ATLSPGST------ 4155
Query: 252 VKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQ-VRAASAPAKGT 310
+ S + S + +P T + + + I + AS P +
Sbjct: 4156 -----------------TASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSS 4198
Query: 311 PGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAK------- 363
G T P AS T G EE + S SS +P + + +
Sbjct: 4199 TGSLHTTLTP------ASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHS 4252
Query: 364 --ASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKR----EEDSQSSSEES 417
+S T+ A+S S + PG TG A+ ++ E + S S
Sbjct: 4253 RPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGS 4312
Query: 418 DSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRS 477
P +G + + S SPR +P PA+ S
Sbjct: 4313 TETTALPGSTTTAGLSEK----STTFYSSPR-----SPDTTLSPASTT---------SSG 4354
Query: 478 SSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQ 537
SEES + +M+ P V ST G + PG +T ++
Sbjct: 4355 VSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPG----STTASS 4410
Query: 538 VGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAV 597
+G + SS G T + P + G + + P S P P
Sbjct: 4411 LGP--------ESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGS 4462
Query: 598 QVKAEKPMDNSESSEESSDSADSEEAPAAMTAA------------QAKPALKIPQTKACP 645
+ S + + +S D+ AP T+A + P +
Sbjct: 4463 TTR----QGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTL 4518
Query: 646 KKTNTTASAKVAPVRVGTQ-APRKAGTA-----TSPAGSSPAVAGGTQRPAEDSSSSEES 699
++ + + +PV T +P ++ T+ ++ SSP P +++S
Sbjct: 4519 GRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGE 4578
Query: 700 DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTV---TQVKA 756
+S + T+ A S L + S PG T T + +
Sbjct: 4579 ESTTSHSSTTHTISSAPSTTSALVEEPTSYHSS-----------PGSTATTHFPDSSTTS 4627
Query: 757 EKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAA 816
+ E+S +S D+ PA+ TSV ++ +P ++ + T + PG T
Sbjct: 4628 GRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISS---GSMETTALPGSTTTPG 4684
Query: 817 AQAKQR----SPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSE 872
K SPS P +ST L R S VATA SG E
Sbjct: 4685 LSEKSTTFHSSPSST-PTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVE 4743
Query: 873 EESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGP-----SAAQAG 927
E + A + PG T S+ +G
Sbjct: 4744 EST-----------------------------------AYHSSPGSTQTMHFPESSTASG 4768
Query: 928 KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKA 987
+ ++S +S + +P + TSA V +P P G AT ++++T
Sbjct: 4769 RSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSP-----GSIATTHFPESSTT--SG 4821
Query: 988 RASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESS 1047
R+ ESTA SS + TN +T AH + +G + +
Sbjct: 4822 RSEESTASHSSPD------------------TNGITPLPAH------FTTSGRIAESTTF 4857
Query: 1048 RISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDD 1107
IS G + A+ T P S +ST + + R P T +P S
Sbjct: 4858 YISPGSMETTLAS-----TATTPGLSAKSTILYSSS----RSP------DQTLSPASMTS 4902
Query: 1108 SEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEET----AAESSEDDVVAPSQ 1163
S S + +S + A+S HT P + T L +E+ + S + ++P
Sbjct: 4903 SSISGEPTSLYSQ-------AESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGS 4955
Query: 1164 SLLSGYMTPGLTP---ANSQASKATPKLDSSPSVS 1195
S + TP S S +P + P +S
Sbjct: 4956 ITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLS 4990
Score = 87.4 bits (215), Expect = 9e-17
Identities = 206/1047 (19%), Positives = 352/1047 (33%), Gaps = 159/1047 (15%)
Query: 328 SQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKG-- 385
S T +G EE + S S + P+ A KTS + +AS P
Sbjct: 214 SSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTT 273
Query: 386 -----------AAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA--PAQAKPSGK 432
++P P +T +G E+ + S S + A + P
Sbjct: 274 AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVS 333
Query: 433 APQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGK--------QEEDSRSSSEESDS 484
+ S P P GP + + + S E+ +
Sbjct: 334 QESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEAST 393
Query: 485 DREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEED 544
+ + P + +T P K P P G T SA V
Sbjct: 394 PVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSG-----TTSAFV------ 442
Query: 545 SESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPT-SSP---AKGPPQKAGPVAVQVK 600
S++ SS SS PT A +LG+ ++ P SSP A PP + V+
Sbjct: 443 KLSTTYHSSPSS---TPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVE 499
Query: 601 AEKPMDNSESS-------EESSDSADSEEAPA-------------AMTAAQAKPAL--KI 638
S S E S+ S SEE+ + TAA A + +
Sbjct: 500 ESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSL 559
Query: 639 PQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEE 698
T+ + ++T S + + +P T PAGS+P+V G P+ SS S E
Sbjct: 560 GSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSME 619
Query: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 758
+ T + GL K+ + ++P P T + +
Sbjct: 620 T-----------TALPGSTTKPGLSEKSTTF--------YSSPRSPDTTHLPASMTSSGV 660
Query: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 818
E+S +S S A P ++ ++ + A+ +P T +PG TA++
Sbjct: 661 SEESTTSHSRPGSTHTTAFPG---STTMPGLSQESTASHSSPGPTDTTLSPGS-TTASSL 716
Query: 819 AKQRSPSKVKPPVRN----PQNSTVLARGPASVP----------SVGKAVATAAQAQTGP 864
+ + +P P N+T AS+P ++ A +T Q ++
Sbjct: 717 GPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGES-T 775
Query: 865 EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKT----G 920
S S +++ T A V+PS +H +++ S R + T
Sbjct: 776 TFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSS 835
Query: 921 PSAAQA---GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 977
P + Q + D + EES + + S+ + +P + P +T
Sbjct: 836 PGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATT 895
Query: 978 AQAASTPRKARASESTARSSSSESEDEDVIPA------------TQCLTPG-IRTNVVTM 1024
S+ R+ ESTA SS ++ V+PA T ++ G + T +
Sbjct: 896 HFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPG 955
Query: 1025 PTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATS-----PQSTSV 1079
T P ++ +++ +S ++ +S ++ + + P ++ P ST+
Sbjct: 956 STTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTT 1015
Query: 1080 QAKGTNKLRKPKLPEVQQATKAPESSDDSEDS-----SDSSSGSEEDGEGP--------- 1125
+ P T P S+ S S S SSSGS + P
Sbjct: 1016 PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFG 1075
Query: 1126 -------QGAKSAHTLVGPTPSRTETLVEET----AAESSEDDVVAPSQSL---LSGYMT 1171
S HT + P + + +VE + ++ S ++P+ S L G T
Sbjct: 1076 QESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGEST 1135
Query: 1172 PGLT-PANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQA--AGMLSPKT--GGK 1226
T PA++ + + P ++P ST + P + +G T
Sbjct: 1136 AFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSS 1195
Query: 1227 EAASGTTPQKSRKPKKGAGNPQASTLA 1253
ASGTTP + G G S ++
Sbjct: 1196 PDASGTTPSSAHSTTSGRGESTTSRIS 1222
>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
Length = 1952
Score = 100 bits (248), Expect = 1e-20
Identities = 240/1201 (19%), Positives = 405/1201 (33%), Gaps = 130/1201 (10%)
Query: 55 QTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVL- 113
+T+ G K+ + ++ P ST+ +E + + ST++++
Sbjct: 219 RTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPG-----STDTTLSP 273
Query: 114 GADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTL--VS 171
G PSS+ ++ G T + T T + LL +P S+ S +TTL S
Sbjct: 274 GTTTPSSLGPESTTFHSSPGYTKTTRLPDNT--TTSGLLEASTPVHSSTGSPHTTLSPAS 331
Query: 172 ETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTK 231
T EG F + S + ++S S T PS P S+ ST
Sbjct: 332 STTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLS---TTYHSSPSSTPT-THFSASSTT 387
Query: 232 ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESS---EEGSESEEEAPAGTR 288
+ ++ P +P PPA+ A E ++ GS P +
Sbjct: 388 LGHSEESTPVHS-----SPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESST 442
Query: 289 SQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSD 348
+ + E + + TP A A ++ S + + S E S
Sbjct: 443 TSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESK 502
Query: 349 SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREE 408
+ +P A A A S + S P+ S A PG T + G E+
Sbjct: 503 ASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGST------TKPGLSEK 556
Query: 409 DSQ-SSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQ 467
+ SS S PA SG ++ES + P T +
Sbjct: 557 STTFYSSPRSPDTTHLPASMTSSG----------VSEESTTSHSRPGSTHTTAFPGSTTM 606
Query: 468 VGKQEEDSRSSSEESDSDREALAAMNAA----------QVKPLGKSPQVKPASTMGMGPL 517
G +E + S S +D A +P + P +T G L
Sbjct: 607 PGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLL 666
Query: 518 GKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQ 577
+ + PV P T + G ES++ S SS+ PA + ++
Sbjct: 667 -EASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSND-----TRPAPPTTTSAFVE 720
Query: 578 AKPTS--SPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPA 635
TS SP+ P ++ + ++ S + S S + P + T +
Sbjct: 721 PSTTSHGSPSSIPTTH---ISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGR--- 774
Query: 636 LKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSS 695
++ ++TT + AP +SP ++ + + S
Sbjct: 775 ----GEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE 830
Query: 696 SEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVK 755
S S S ++ TG V A+S L ++ + P+ + TA LPG T T
Sbjct: 831 SIASHSSQDATGTIVL--PARSTNSVLLGESTTSPISSGSMETTA--LPGS---TTTPGL 883
Query: 756 AEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTA 815
+E+ SS + + AS S + T + + P + + + + PG ++
Sbjct: 884 SERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPG--LSR 941
Query: 816 AAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEES 875
+ SP + +T L P + P + +T A G +G SE+ +
Sbjct: 942 HSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPI--SSGSTETTALPGSTTTAGLSEKST 999
Query: 876 DSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKT------GPSAAQAGKQ 929
T S T A+ + S + + PG T G + Q
Sbjct: 1000 -------TFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQ 1052
Query: 930 DDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARA 989
+ + S S +D T+A + P + +GP +T +T
Sbjct: 1053 ESTASHSSPGSTDTTLSPRSTTASSLGP-----ESTTFHSGPGSTETTLLPDNTTASGLL 1107
Query: 990 SESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRI 1049
ST SS+ S + PA G T + P++ + A S+ E S
Sbjct: 1108 EASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTM--PAPPTTTSAFVELSTT 1165
Query: 1050 SDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPE------VQQAT---K 1100
S G P T SA T S +ST+V + P V+++T
Sbjct: 1166 SHGSPSSIPTTHF-SASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHS 1224
Query: 1101 APESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVA 1160
+P S+ S++ + + + HT+ P PS T LVEE + S +A
Sbjct: 1225 SPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSP-PSTTSALVEEPTSYHSSPGSIA 1283
Query: 1161 ----PSQSLLSGYM-----------TPGLTP------ANSQASKATPKLDSSPSVSSTLA 1199
P S SG T G+TP + + +++T S S+ +TLA
Sbjct: 1284 TTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLA 1343
Query: 1200 A 1200
+
Sbjct: 1344 S 1344
Score = 81.6 bits (200), Expect = 5e-15
Identities = 199/999 (19%), Positives = 341/999 (34%), Gaps = 134/999 (13%)
Query: 328 SQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKG-- 385
S T +G EE + S S + P+ A KTS + +AS P
Sbjct: 135 SSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTT 194
Query: 386 -----------AAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA--PAQAKPSGK 432
++P P +T +G E+ + S S + A + P
Sbjct: 195 AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVS 254
Query: 433 APQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGK--------QEEDSRSSSEESDS 484
+ S P P GP + + + S E+ +
Sbjct: 255 QESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEAST 314
Query: 485 DREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEED 544
+ + P + +T P K P P G T SA V
Sbjct: 315 PVHSSTGSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSG-----TTSAFV------ 363
Query: 545 SESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPT-SSP---AKGPPQKAGPVAVQVK 600
S++ SS SS PT A +LG+ ++ P SSP A PP + V+
Sbjct: 364 KLSTTYHSSPSS---TPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVE 420
Query: 601 AEKPMDNSESS-------EESSDSADSEEAPA-------------AMTAAQAKPAL--KI 638
S S E S+ S SEE+ + TAA A + +
Sbjct: 421 ESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSL 480
Query: 639 PQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEE 698
T+ + ++T S + + +P T PAGS+P+V G P+ SS S E
Sbjct: 481 GSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSME 540
Query: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 758
+ T + GL K+ + ++P P T + +
Sbjct: 541 T-----------TALPGSTTKPGLSEKSTTF--------YSSPRSPDTTHLPASMTSSGV 581
Query: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 818
E+S +S S A P ++ ++ + A+ +P T +PG TA++
Sbjct: 582 SEESTTSHSRPGSTHTTAFPG---STTMPGLSQESTASHSSPGPTDTTLSPGS-TTASSL 637
Query: 819 AKQRSPSKVKPPVRN----PQNSTVLARGPASVP----------SVGKAVATAAQAQTGP 864
+ + +P P N+T AS+P ++ A +T Q ++
Sbjct: 638 GPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGES-T 696
Query: 865 EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKT----G 920
S S ++ T A V+PS +H +++ S R + T
Sbjct: 697 TFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSS 756
Query: 921 PSAAQA---GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 977
P + Q + D + EES + + S+ + +P + P +T
Sbjct: 757 PGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATT 816
Query: 978 AQAASTPRKARASESTARSSSSESEDEDVIPA---TQCLTPGIRTNVVTMPTAHPRIAPK 1034
S+ R+ ES A SS ++ V+PA L T+ ++ + P
Sbjct: 817 HFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPG 876
Query: 1035 ASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAK--GTNKLRKP-- 1090
++ S + ++ S + PAT + A T S +ST+ ++ T+ P
Sbjct: 877 STTTPGLSERSTTFHSSPR---SPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDS 933
Query: 1091 -KLPEVQQATKAPESSDDSEDSS--DSSSGSEEDGE---GPQGAKSAHTLVGPTPSRTET 1144
P + + + SS S D++ +S+ + GE P + S T P + T
Sbjct: 934 TTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAG 993
Query: 1145 LVEET----AAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKAT---PKLDSSPSVSST 1197
L E++ ++ S D ++P+ + SG T + S T P + P VS
Sbjct: 994 LSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQE 1053
Query: 1198 LAAKDDPDGKQE---AKPQQAAGMLSPKTGGKEAASGTT 1233
A G + + A L P++ + G+T
Sbjct: 1054 STASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGST 1092
Score = 80.1 bits (196), Expect = 1e-14
Identities = 247/1220 (20%), Positives = 398/1220 (32%), Gaps = 222/1220 (18%)
Query: 76 TRVSDPISTSESSEEEEEAEAET-AKATPRL--ASTNSSVLGADLPSSMKEKAKAETEKA 132
T D + S SEE + + + A AT L ST S ++G PS + + T
Sbjct: 486 THFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALP 545
Query: 133 GKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA---AKPG 189
G T + K+ S +SP + P++ T+ E S G+ A PG
Sbjct: 546 GSTTKP---GLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPG 602
Query: 190 MVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVT 249
+ S + SS TD ++ P ASS+ + + PG + T
Sbjct: 603 STTMPGLSQESTASHSSPGPTDT----TLSPGSTTASSLGPEYTTFHSR---PGST-ETT 654
Query: 250 PQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKG 309
A P S S + S PAG+ ++ + S
Sbjct: 655 LLPDNTTASGLLEASMPVHSSTRSPHTTLS----PAGSTTR----------QGESTTFHS 700
Query: 310 TPGKGAT-PAPPGKAGAVA--SQTKAGKPEE---------DSESSSEESSDSEEETPAAK 357
P T PAPP A S T G P + S E S + +P +
Sbjct: 701 WPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGST 760
Query: 358 ALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEES 417
+ S TS G S + S + AP + A E S SS S
Sbjct: 761 QTMHFPESDTTSGRGEESTTSHSSTTHTISSAP--------STTSALVEEPTSYHSSPGS 812
Query: 418 DSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPA------AAQVQVGKQ 471
+ P + SG++ + A+ + + G P R T + + G
Sbjct: 813 TATTHFPDSSTTSGRSEESIASHSSQDAT---GTIVLPARSTNSVLLGESTTSPISSGSM 869
Query: 472 EEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGP 531
E + S + E +++ P + + PAST G + + G
Sbjct: 870 ETTALPGSTTTPGLSERSTTFHSS---PRSPATTLSPASTTSSGVSEEST--TSHSRPGS 924
Query: 532 ATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQK 591
+A S +S SS G T + PA S L +PT+SP +
Sbjct: 925 THTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA---STTTXLVGEPTTSPISSGSTE 981
Query: 592 AGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTT 651
+ + S + S S D+ +PA+ T++ ++ P T+TT
Sbjct: 982 TTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSR--PGSTHTT 1039
Query: 652 ASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVT 711
A G+ T P S + A + + D++ S S +
Sbjct: 1040 AFP---------------GSTTMPGVSQESTASHSSPGSTDTTLSPRSTT---------- 1074
Query: 712 VGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDS 771
A S+G P + G G T T + + S E +
Sbjct: 1075 ---ASSLG----------PESTTFHSGP--------GSTETTLLPDNTTASGLLEASTPV 1113
Query: 772 EEAAASPAQVKTSVKKTQAKANPAAARA-PSAKGTISAPGKVVTAAAQ---AKQRSPSKV 827
+ SP + T + ++ PS+K T+ AP +A + SPS +
Sbjct: 1114 HSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSI 1173
Query: 828 KPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQV 887
P +ST R S VA A SG EE +
Sbjct: 1174 -PTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEEST------------ 1220
Query: 888 KPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGP-----SAAQAGKQDDSGSSSEESDSD 942
A + PG T S+ +G+ ++S +S +
Sbjct: 1221 -----------------------AYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHT 1257
Query: 943 GEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESE 1002
+P + TSA V +P P G AT ++++T R+ ESTA SS ++
Sbjct: 1258 ISSPPSTTSALVEEPTSYHSSP-----GSIATTHFPESSTT--SGRSEESTASHSSPDTN 1310
Query: 1003 DEDVIPA------------TQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRIS 1050
+PA T ++PG + P ++ K+++ +SS +S
Sbjct: 1311 GITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLS 1370
Query: 1051 DGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSED 1110
PA+ S++ + P S QA+ T+ T P S+ S
Sbjct: 1371 -------PASMTSSSI----SGEPTSLYSQAESTH------------TTAFPASTTTSGL 1407
Query: 1111 SSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSED----DVVAPSQSLL 1166
S +S++ + G S T + P T + +E S+ V+P+ + +
Sbjct: 1408 SQESTTFHSKPG-------STETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTV 1460
Query: 1167 SGYMTPGLTPANSQASKATPKLDSSPSVS----STLAAKDDPDGKQEAKPQQAA----GM 1218
G T +S S T S ++S + D P P G
Sbjct: 1461 PGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQ 1520
Query: 1219 LSPKTGGKEAASGTTPQKSR 1238
S A+GTTP +R
Sbjct: 1521 ESTAFHSSSDATGTTPLPAR 1540
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 99.4 bits (246), Expect = 2e-20
Identities = 225/1089 (20%), Positives = 404/1089 (37%), Gaps = 131/1089 (12%)
Query: 54 QQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEE--EEEAEAETAKATPRLASTNSS 111
++ E G + EE L+ K + E+ EE +EE E + S SS
Sbjct: 1357 EEIEETGGEGLQEEGVQLEEVKEGPEGGLQ-GEALEEGLKEEGLPEEGSVHGQELSEASS 1415
Query: 112 VLGADLPSSMKEKAKAETEKAGKTGNSM-PHPATGKTVANLLSGKSPRKSAEPSANTTLV 170
G +E + E+AG+ S P PA G + EP+ + +
Sbjct: 1416 PDG----KGSQEDDPVQEEEAGRASASAEPCPAEG--------------TEEPTEPPSHL 1457
Query: 171 SETEEEGSVPAFGAAAKPGM------VSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVK 224
SET+ S G+ +PG+ GQ + ++ T +++ + +
Sbjct: 1458 SETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQPTQGAAERSSSVACSAALDCDPI 1517
Query: 225 ASSVSTKESPARKAAPAPGKVGDVTPQ--VKGGALPPAKRAKKPEEESESSEEGSESEEE 282
SV K++ A V ++ + ++ L A+ ++ ++ ++ ++ E +
Sbjct: 1518 WVSVLLKKTEKAFLAHLASAVAELRARWGLQDNDLLDQMAAELQQDVAQRLQDSTKRELQ 1577
Query: 283 APAGTRSQVK--------ASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGK 334
G ++ E +LQ + +G A G + S T +
Sbjct: 1578 KLQGRAGRMVLEPPREALTGELLLQTQQRRHRLRGLRNLSAFSERTLGLGPL-SFTLEDE 1636
Query: 335 PEEDSESSSEESSDSE-EETPAAKALLQAKASGKTSQ--VGAASAPAKES--------PR 383
P + S+ ++E EE +A ++ K S + + +GA P KE+ +
Sbjct: 1637 PALSTALGSQLGEEAEGEEFCPCEACVRKKVSPMSPKATMGATRGPIKEAFDLQQILQRK 1696
Query: 384 KG------AAPAPPGKTGP------AVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSG 431
+G AA PGKT V A+ G SQ + + E +Q
Sbjct: 1697 RGEHTDGEAAEVAPGKTHTDPTSTRTVQGAEGGLGPGLSQGPGVDEGEDGEG-SQRLNRD 1755
Query: 432 KAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAA 491
K P++ A A R+G +A ++G+ E++ SE ++ +
Sbjct: 1756 KDPKLGEAEGDAMAQEREGKT-----HNSETSAGSELGEAEQEGEGISERGETGGQGSGH 1810
Query: 492 MNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDS-ESSSE 550
+ Q + Q P + G + P G+ P + + + E D+ E+ E
Sbjct: 1811 EDNLQGEAAAGGDQ-DPGQSDGAEGI---EAPEAEGEAQPESEGVEAPEAEGDAQEAEGE 1866
Query: 551 ESSDSSDGEVPTAVAPAQEKSLGNIL-----QAKPTSSPAKGPP--QKAGPVAVQVKAEK 603
+S D E P A AQ +S + +P S A+ P ++A P V+A +
Sbjct: 1867 AQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALE 1926
Query: 604 PMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTAS-AKVAPVRVG 662
E E +++ ++EEA A Q +P ++ +++ ++ + + V V
Sbjct: 1927 TEGEDEPESEGAEAQEAEEA-AQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVE 1985
Query: 663 TQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL 722
TQ S +P G Q E++ ESD E Q KS G+
Sbjct: 1986 TQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQP--ESDGVE---------AQPKSEGEEA 2034
Query: 723 QVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKA-EKQEDSESSEEESDSEEAAASPAQV 781
Q +G G P V+A E +E+++ +E E E A P
Sbjct: 2035 QEV-----------EGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESE 2083
Query: 782 KTSVKKTQAKANPAA--ARAPSAKGTISAPGKVVTAAAQAKQRSPSK-VKPPVRN----P 834
++ + +A P + AP A+G + + + + S+ ++ P P
Sbjct: 2084 DVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQP 2143
Query: 835 QNSTVLAR---GPASVPSVGKAVATAAQAQTGPE-------EDSGSSEEESDSEEEAETL 884
++ V A+ G A S G A A+ + PE E G ++ ES+ E E
Sbjct: 2144 ESEGVEAQDAEGEAQPESEG-IEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAE 2202
Query: 885 AQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGE 944
+ +P + + A A+ P P G+ P + + Q + S + S DG+
Sbjct: 2203 GEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPES-EGETQGEKKGSPQVSLGDGQ 2261
Query: 945 APAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDE 1004
+ A S+ + P P SP G TP Q + T + + S +SE++
Sbjct: 2262 SEEASESSSPV--PEDRPTPPPSPGGD--TPHQRPGSQTGPSSSRASSWGNCWQKDSEND 2317
Query: 1005 DVIPATQCLTPGIR-TNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVD 1063
V+ T+ +P + T R+ P++S + + SR + EG Q D
Sbjct: 2318 HVLGDTR--SPDAKSTGTPHAERKATRMYPESSTSEQEEAPLGSRTPEQGASEGYDLQED 2375
Query: 1064 SAVGTLPAT 1072
A+G+L T
Sbjct: 2376 QALGSLAPT 2384
Score = 84.7 bits (208), Expect = 6e-16
Identities = 133/677 (19%), Positives = 254/677 (37%), Gaps = 48/677 (7%)
Query: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKE-KA 125
ED + R DP + E E +A A+ + + T++ G++L + +E +
Sbjct: 1744 EDGEGSQRLNRDKDP----KLGEAEGDAMAQEREGKTHNSETSA---GSELGEAEQEGEG 1796
Query: 126 KAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA 185
+E + G G+ G+ A + P +S A E E E + G
Sbjct: 1797 ISERGETGGQGSGHEDNLQGEAAAG--GDQDPGQS--DGAEGIEAPEAEGEAQPESEGVE 1852
Query: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKV 245
A A +A+ ++ S + + EG+ + V+ + P + A AP
Sbjct: 1853 APEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAE 1912
Query: 246 GDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQ---VKASEKILQVRA 302
+ P+ + + +PE E ++E E+ +EA T+ + +++ E + +
Sbjct: 1913 KEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQP 1972
Query: 303 ASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES---SDSEEETPAAKAL 359
S + + T G+A + +A + E + + + EE+ SD E P ++
Sbjct: 1973 ESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGE 2032
Query: 360 LQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDS 419
+ G+T + + P + AP + A+ + + E ++ SE+ D+
Sbjct: 2033 EAQEVEGETQKTEGDAQPESD-----GVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDA 2087
Query: 420 EEEAPAQAKPSGKAPQVRAASAPAKESPRKG-AAPAPPRKTGPAAAQVQVGKQEEDSRSS 478
+EA +A+P + V A A + +G AP + P + ++ + E +++
Sbjct: 2088 -QEAEGEAQPESEG--VEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPE 2144
Query: 479 SEESDS-DREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKG-AGPVPPGKVGP-ATPS 535
SE ++ D E A + ++ + +P P +G A P G P A
Sbjct: 2145 SEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGE 2204
Query: 536 AQVGKWEEDSESSSEESSDSSDG-EVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKA-- 592
AQ ++ + EE+ +G E P A AQ +S G T KG PQ +
Sbjct: 2205 AQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGE------TQGEKKGSPQVSLG 2258
Query: 593 -GPVAVQVKAEKPMDNSESSEESSDSADS-EEAPAAMTAAQAKPALKIPQTKACPKKTNT 650
G ++ P+ + S D+ + P + T + A + +
Sbjct: 2259 DGQSEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDH 2318
Query: 651 TASAKVAPVRVGTQAPRKAGTAT-----SPAGSSPAVAGGTQRPAEDSSSSEESDSEEEK 705
+P T P AT S G++ P + +S + ++
Sbjct: 2319 VLGDTRSPDAKSTGTPHAERKATRMYPESSTSEQEEAPLGSRTPEQGASEGYDLQEDQAL 2378
Query: 706 TGLAVT--VGQAKSVGK 720
LA T VG+A G+
Sbjct: 2379 GSLAPTEAVGRADGFGQ 2395
Score = 84.3 bits (207), Expect = 8e-16
Identities = 221/1106 (19%), Positives = 388/1106 (35%), Gaps = 176/1106 (15%)
Query: 183 GAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPS-----VKPAQVKASSVSTKESPAR- 236
G A + G+ G + S S+ + +GK S V+ + +S S + PA
Sbjct: 1387 GEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEG 1446
Query: 237 --KAAPAPGKVGDVTPQVK----GGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQ 290
+ P + + P G L P +KP + +E ++++ A RS
Sbjct: 1447 TEEPTEPPSHLSETDPSASERQSGSQLEPG--LEKPPGATMMGQEHTQAQPTQGAAERSS 1504
Query: 291 VKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSE 350
A L + A A A AVA + +A +D++ + +++ +
Sbjct: 1505 SVACSAALDCDPIWVSVLLKKTEKAFLAH--LASAVA-ELRARWGLQDNDLLDQMAAELQ 1561
Query: 351 EETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKRE--- 407
++ A+ L + G A E PR+ TG + + Q +
Sbjct: 1562 QDV--AQRLQDSTKRELQKLQGRAGRMVLEPPREAL-------TGELLLQTQQRRHRLRG 1612
Query: 408 --------EDSQSSSEESDSEEEAPAQAKPSGKAPQVRAAS---APAKESPRKGAAPAPP 456
E + S + E+ PA + G A P + RK +P P
Sbjct: 1613 LRNLSAFSERTLGLGPLSFTLEDEPALSTALGSQLGEEAEGEEFCPCEACVRKKVSPMSP 1672
Query: 457 RKT-----GPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPAST 511
+ T GP + Q+ R E +D + AA+V P GK+ P ST
Sbjct: 1673 KATMGATRGPIKEAFDL--QQILQRKRGEHTDGE--------AAEVAP-GKT-HTDPTST 1720
Query: 512 M-------GMGPLGKGAGP-VPPGKVGPATP------SAQVGKWEEDSESSSEES-SDSS 556
G+GP G GP V G+ G + ++G+ E D+ + E + +S
Sbjct: 1721 RTVQGAEGGLGP-GLSQGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNS 1779
Query: 557 DGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSD 616
+ + + A+++ G I + T G A + P SD
Sbjct: 1780 ETSAGSELGEAEQEGEG-ISERGETGGQGSGHEDNLQGEAAAGGDQDP--------GQSD 1830
Query: 617 SADSEEAPAAMTAAQAKP-ALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT-- 673
A+ EAP A AQ + ++ P+ + ++ A + P +AP G A
Sbjct: 1831 GAEGIEAPEAEGEAQPESEGVEAPEAEGDAQE----AEGEAQPESEDVEAPEAEGEAQPE 1886
Query: 674 SPAGSSPAVAGGTQRPAEDSSSSE---ESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVP 730
S +P Q +E + + E E+ E E T G+ + +G + + A
Sbjct: 1887 SEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEA 1946
Query: 731 VKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEE-ESDSEEAAASPAQVKTSVKKTQ 789
+ + GQ TQ ++E E E+ EE + +SE+ A +V+T + +
Sbjct: 1947 AQEAEGQ--------------TQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGE 1992
Query: 790 AKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPS 849
A+ AP A+G + + + + P + + T G A S
Sbjct: 1993 AQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPES 2052
Query: 850 VG----KAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKE 905
G +A A +A+ +E G + ES+ + E + +P + AP E
Sbjct: 2053 DGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESE-----GVEAPEAE 2107
Query: 906 SPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPN 965
G A G P + + G + E++ + + + AQ
Sbjct: 2108 ----GEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQ----------DA 2153
Query: 966 RSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMP 1025
A P + +AQ A + A + E++ E + + P
Sbjct: 2154 EGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPE--------------SEGIEAP 2199
Query: 1026 TAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTN 1085
A P+ A ++E + + E + A G S T + KG+
Sbjct: 2200 EAEGEAQPELEGVEAPEAEEEA------QPEPEGVETPEAEGEAQPESEGETQGEKKGS- 2252
Query: 1086 KLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGP---QGAKSAH----TLVGPT 1138
P+V SE++S+SSS ED P G + H + GP+
Sbjct: 2253 -------PQVSL------GDGQSEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPS 2299
Query: 1139 PSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTL 1198
SR + +S D V+ ++S + G A +A++ P+ +S + L
Sbjct: 2300 SSRASSWGNCWQKDSENDHVLGDTRS--PDAKSTGTPHAERKATRMYPESSTSEQEEAPL 2357
Query: 1199 AAKDDPDGKQEA---KPQQAAGMLSP 1221
++ G E + QA G L+P
Sbjct: 2358 GSRTPEQGASEGYDLQEDQALGSLAP 2383
Score = 65.1 bits (157), Expect = 5e-10
Identities = 147/741 (19%), Positives = 265/741 (35%), Gaps = 95/741 (12%)
Query: 767 EESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKG----TISAPGKVVTAAAQAKQR 822
EE++ EE A V+ V KA A R P + I + +A +
Sbjct: 1649 EEAEGEEFCPCEACVRKKVSPMSPKATMGATRGPIKEAFDLQQILQRKRGEHTDGEAAEV 1708
Query: 823 SPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDS----- 877
+P K ST +G +G ++ G E+ GS D
Sbjct: 1709 APGKT----HTDPTSTRTVQGAEG--GLGPGLSQGPGVDEG-EDGEGSQRLNRDKDPKLG 1761
Query: 878 EEEAETLAQVKPSGKTHQIR-AALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDD----- 931
E E + +AQ + GKTH +A + E+ ++G + G+TG + G +D+
Sbjct: 1762 EAEGDAMAQER-EGKTHNSETSAGSELGEAEQEGEGISERGETGGQGS--GHEDNLQGEA 1818
Query: 932 -SGSSSEESDSDG----EAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 986
+G + SDG EAP A AQ P V+ + +AQ S +
Sbjct: 1819 AAGGDQDPGQSDGAEGIEAPEAEGEAQ---PESEGVEAPEAEGDAQEAEGEAQPESEDVE 1875
Query: 987 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKA-SMAGASSSKE 1045
A +E A+ S + E + Q + G P A P+ S+ + E
Sbjct: 1876 APEAEGEAQPESEDVETPEAEWEVQPESEGAEA-----PEAEKEAQPETESVEALETEGE 1930
Query: 1046 SSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQA---TKAP 1102
S+G + + A G T P+S ++++ + +P+ +V+ +
Sbjct: 1931 DEPESEGAEAQEAEEAAQEAEGQ---TQPESEVIESQEAEEEAQPESEDVEALEVEVETQ 1987
Query: 1103 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRT------------ETLVEETA 1150
E+ +++ S+ E +GE + + A ++ ET E
Sbjct: 1988 EAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGD 2047
Query: 1151 AESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQ-E 1209
A+ D V AP + + A +A + +D+ + + + + E
Sbjct: 2048 AQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAE 2107
Query: 1210 AKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPL 1269
+ Q+A G+ +P+T G+ A + +G P++ + Q
Sbjct: 2108 GEAQKAEGIEAPETEGE--AQPESEGIEAPEAEGEAQPESEGVEAQDA------------ 2153
Query: 1270 NEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKK 1329
E + Q + + E+E + ++ + +G E++ + P A + +
Sbjct: 2154 -EGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEG-EAQPESEGIEAPEAEGEAQPELEG 2211
Query: 1330 LGAGEGGE-ASVSPEKTSTT-SKGKAKRDKASGDVKEKKGKG--SLG-----------SQ 1374
+ A E E A PE T ++G+A+ + EKKG SLG S
Sbjct: 2212 VEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSP 2271
Query: 1375 GAKDEPEEELQKGMGTVEG--GDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDS 1432
+D P G T G Q+ P S + + +KD E + K +
Sbjct: 2272 VPEDRPTPPPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKST 2331
Query: 1433 ESPSQKKKKKK----KKTAEQ 1449
+P ++K + T+EQ
Sbjct: 2332 GTPHAERKATRMYPESSTSEQ 2352
Score = 61.2 bits (147), Expect = 7e-09
Identities = 266/1415 (18%), Positives = 501/1415 (35%), Gaps = 208/1415 (14%)
Query: 140 PHPATGKTVANLLS-GKSPRKSAEPSANTTLVSETEEEGSVPAFGA--AAKPGMVSAGQA 196
PH + + + S G+ R + +PS+ L E+G+V + ++PG A +A
Sbjct: 778 PHTSDSCSKSGAASLGEEARDTPQPSSPLVLQVGRPEQGAVGPHRSHCCSQPGTQPAQEA 837
Query: 197 DSSSEDTSSSSDETDVEGKPSVKPA-QVKASSVSTKESPARKAAPAPGKVGDVTPQVKGG 255
+S P +P Q ++SS + S + A PG
Sbjct: 838 QRGPSPEASWLCGRYCPTPPRGRPCPQRRSSSCGSTGSSHQSTARGPGG----------- 886
Query: 256 ALPPAKRAKKP-EEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG 314
P + ++P S G+ A G S+ + EK L R+ P G
Sbjct: 887 --SPQEGTRQPGPTPSPGPNSGASRRSSASQGAGSRGLSEEKTL--RSGGGPQGQEEASG 942
Query: 315 ATPA--PPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQA---------- 362
+P+ P AV + PEE + E + +E T AA L+
Sbjct: 943 VSPSSLPRSSPEAVVREWLDNIPEEPILMTYELA---DETTGAAGGGLRGPEVDPGDDHS 999
Query: 363 -KASGKTSQVGAASAPAK--ESPRKGAAPAPPGKTGPAVAKA-QAGKREEDSQSSSEESD 418
+ G+ +Q G S + P A TGP + G E + E+
Sbjct: 1000 LEGLGEPAQAGQQSLEGDPGQDPEPEGALLGSSDTGPQSGEGVPQGAAPEGVSEAPAEAG 1059
Query: 419 SEEEAPAQAKPSGKAPQVRAASAP----AKESPRKGAAPAPPRKTGPAAAQVQVGKQEED 474
++ EAPA + S +A R +++ A ++G + P + P A ++
Sbjct: 1060 ADREAPAGCRVSLRALPGRVSASTQIMRALMGSKQGRPSSVPEVSRPMARRLSCSAGALI 1119
Query: 475 SRSSS-----EESDSDREALAAMNAAQVKPL-GKSPQVKPASTMGMGPLGKGAGPVPPGK 528
+ +S E+ S + ++ + + L S + P +G L G + +
Sbjct: 1120 TCLASLQLFEEDLGSPASKVRFKDSPRYQELLSISKDLWPGCDVGEDQLDSGLWELTWSQ 1179
Query: 529 VGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL---GNILQAK-----P 580
P S + + + SS + S S G ++V A + +L G L K P
Sbjct: 1180 ALPDLGSHAMTENFTPTSSSGVDISSGSGGSGESSVPCAMDGTLVTQGTELPLKTSNQRP 1239
Query: 581 TSSPAKGP------PQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKP 634
S + P Q P + +A N + +E S+ + + +
Sbjct: 1240 DSRTYESPGDLENQQQCCFPTFLNARACACATNEDEAERDSEEQRASSNLEQLAENTVQE 1299
Query: 635 ALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSS 694
+++ +TK + A + ++ G T+ +
Sbjct: 1300 EVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEE----------TKETEGEGQ 1349
Query: 695 SSEESDSEE-EKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQ 753
EE+ EE E+TG G+GLQ + + + +G L G+ +
Sbjct: 1350 QEEEAQLEEIEETG-----------GEGLQEEGVQLE---EVKEGPEGGLQGEALEEGLK 1395
Query: 754 VKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGT---ISAPG 810
+ +E S +E S++ +Q V++ +A A+A A+GT P
Sbjct: 1396 EEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEPPS 1455
Query: 811 KVVTAAAQAKQR-SPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSG 869
+ A +R S S+++P + P +T++ G+ A Q E S
Sbjct: 1456 HLSETDPSASERQSGSQLEPGLEKPPGATMM----------GQEHTQAQPTQGAAERSSS 1505
Query: 870 SSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQ 929
+ + + +K + K A A A+ R G AA+ +Q
Sbjct: 1506 VACSAALDCDPIWVSVLLKKTEKAFLAHLASAVAELRARWGLQDND--LLDQMAAEL-QQ 1562
Query: 930 DDSGSSSEESDSDGEAPAAVTSAQVIKPP-------LIFVDPNRSPAGPAATPAQAQAAS 982
D + + + + + V++PP L+ R A +
Sbjct: 1563 DVAQRLQDSTKRELQKLQGRAGRMVLEPPREALTGELLLQTQQRRHRLRGLRNLSAFSER 1622
Query: 983 T----PRKARASESTARSSS------SESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIA 1032
T P + A S++ E+E E+ P C +R V M +
Sbjct: 1623 TLGLGPLSFTLEDEPALSTALGSQLGEEAEGEEFCPCEAC----VRKKVSPM-------S 1671
Query: 1033 PKASMA--------------------GASSSKESSRISDGKKQEGPATQ--VDSAVGTLP 1070
PKA+M G + E++ ++ GK P + V A G L
Sbjct: 1672 PKATMGATRGPIKEAFDLQQILQRKRGEHTDGEAAEVAPGKTHTDPTSTRTVQGAEGGLG 1731
Query: 1071 ATSPQSTSVQ----AKGTNKLRKPKLPEVQQAT--KAPESSDDSEDSSDSSSGSE--EDG 1122
Q V +G+ +L + K P++ +A + + +S++S+GSE E
Sbjct: 1732 PGLSQGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAE 1791
Query: 1123 EGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQAS 1182
+ +G G + L E AA +D P QS G G+ ++
Sbjct: 1792 QEGEGISERGETGGQGSGHEDNLQGEAAAGGDQD----PGQS--DG--AEGIEAPEAEG- 1842
Query: 1183 KATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGK---EAASGTTPQKS-- 1237
+A P+ S V + A D + + EA+P+ + + +P+ G+ E+ TP+
Sbjct: 1843 EAQPE---SEGVEAPEAEGDAQEAEGEAQPE-SEDVEAPEAEGEAQPESEDVETPEAEWE 1898
Query: 1238 -RKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDT 1296
+ +GA P+A EAQ + V E LE E + ++
Sbjct: 1899 VQPESEGAEAPEAE-------------------KEAQPETESV----EALETEGEDEPES 1935
Query: 1297 TKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRD 1356
+++ E+ + QP + S++ ++ E + E T + + +
Sbjct: 1936 EGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEAL-EVEVETQEAEGEAQ 1994
Query: 1357 KASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDK- 1415
S DV+ + +G + + +PE + + EG + + + +K + D + +
Sbjct: 1995 PESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDG 2054
Query: 1416 -EKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1449
E E +++A++A + E+ + + + A++
Sbjct: 2055 VEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQE 2089
Score = 60.1 bits (144), Expect = 2e-08
Identities = 143/661 (21%), Positives = 245/661 (37%), Gaps = 99/661 (14%)
Query: 56 TSELGRKRKAE----EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSS 111
++++G +RKA ED L + P + E ++ ++ S S
Sbjct: 486 SAQIGAERKAGGSLGEDPGLCIDGAGLGGPEQGGRLTPRARSEEGASSDSSASTGSHEGS 545
Query: 112 VLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVS 171
P KA+AET + + P SP S + L +
Sbjct: 546 SEWGGRPQGCPGKARAETSQQEASEGGDP--------------ASPALSLSSLRSDDLQA 591
Query: 172 ETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTK 231
ET+ +G+ A GAA + G + S + +SS+ T + + + +AS++S+
Sbjct: 592 ETQGQGTEQATGAAVTREPLVLGLSCSWDSEGASSTPSTCTSSQQGQRRHRSRASAMSSP 651
Query: 232 ESP-----ARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAG 286
SP A + P T ++ K+ +P E + ++GS +
Sbjct: 652 SSPGLGRVAPRGHPRHSHYRKDTHSPLDSSV--TKQVPRPPERRRACQDGSVPRYSG-SS 708
Query: 287 TRSQVKASEKILQVRAASAPAK---GTPGKGATPA---------------PPGKAGAVAS 328
+ ++ +AS + + S P++ GT TPA G AG S
Sbjct: 709 SSTRTQASGNLRPPSSGSLPSQDLLGTSSATVTPAVHSDFVSGVSPHNAPSAGWAGDAGS 768
Query: 329 QTKAGKP----EEDSESSSEESSDSEE--ETPAAKALLQAKASGKTSQVGAASAPAKESP 382
+T + P DS S S +S EE +TP + L QVG A P
Sbjct: 769 RTCSPAPIPPHTSDSCSKSGAASLGEEARDTPQPSSPL-------VLQVGRPEQGA-VGP 820
Query: 383 RKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAP 442
+ + PG T PA +AQ G E S + P + +P PQ R++S
Sbjct: 821 HRSHCCSQPG-TQPA-QEAQRGPSPEASWLCGRYCPT----PPRGRP---CPQRRSSSCG 871
Query: 443 AKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGK 502
+ S + A GP + + +Q + S S + R + A+ A + L +
Sbjct: 872 STGSSHQSTA------RGPGGSPQEGTRQPGPTPSPGPNSGASRRSSASQGAGS-RGLSE 924
Query: 503 SPQVKPASTMGMGPLG-KGAGPVPPGKVGPATPSAQVGKWEED---------SESSSEES 552
++ G GP G + A V P + ++P A V +W ++ E + E +
Sbjct: 925 EKTLR----SGGGPQGQEEASGVSPSSLPRSSPEAVVREWLDNIPEEPILMTYELADETT 980
Query: 553 SDSSDGEVPTAVAPAQEKS---LGNILQAKPTS---SPAKGPPQKAGPVAVQVKAEKPMD 606
+ G V P + S LG QA S P + P + A+ ++
Sbjct: 981 GAAGGGLRGPEVDPGDDHSLEGLGEPAQAGQQSLEGDPGQDPEPEG---ALLGSSDTGPQ 1037
Query: 607 NSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAP 666
+ E + + EAPA A + PA +A P + +AS ++ +G++
Sbjct: 1038 SGEGVPQGAAPEGVSEAPAEAGADREAPAGCRVSLRALPGR--VSASTQIMRALMGSKQG 1095
Query: 667 R 667
R
Sbjct: 1096 R 1096
Score = 55.5 bits (132), Expect = 4e-07
Identities = 275/1426 (19%), Positives = 491/1426 (34%), Gaps = 267/1426 (18%)
Query: 114 GADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSET 173
GA SS + A + KT S P + + + PR S E L
Sbjct: 906 GASRRSSASQGAGSRGLSEEKTLRSGGGPQGQEEASGVSPSSLPRSSPEAVVREWL-DNI 964
Query: 174 EEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKES 233
EE + + A + + G D D+ +EG +PAQ A S +
Sbjct: 965 PEEPILMTYELADETTGAAGGGLRGPEVDPG---DDHSLEGLG--EPAQ--AGQQSLEGD 1017
Query: 234 PARKAAPAPGKVG--DVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTR--- 288
P + P +G D PQ G +P + PE SE+ E ++ EAPAG R
Sbjct: 1018 PGQDPEPEGALLGSSDTGPQ-SGEGVP---QGAAPEGVSEAPAEAG-ADREAPAGCRVSL 1072
Query: 289 ----SQVKASEKILQVRAASAPAKGTPGKGATPAPPG------KAGAVAS--------QT 330
+V AS +I+ RA +G P + P AGA+ + +
Sbjct: 1073 RALPGRVSASTQIM--RALMGSKQGRPSSVPEVSRPMARRLSCSAGALITCLASLQLFEE 1130
Query: 331 KAGKPE-----EDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKG 385
G P +DS E S S++ P SG + + P S
Sbjct: 1131 DLGSPASKVRFKDSPRYQELLSISKDLWPGCDVGEDQLDSGLWELTWSQALPDLGSHAMT 1190
Query: 386 AAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKE 445
P +G ++ G E + + + + K S + P R +P
Sbjct: 1191 ENFTPTSSSGVDISSGSGGSGESSVPCAMDGTLVTQGTELPLKTSNQRPDSRTYESPGDL 1250
Query: 446 SPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQ 505
++ P A + E + S + + S+ E LA + L ++ +
Sbjct: 1251 ENQQQCCF--PTFLNARACACATNEDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKE 1308
Query: 506 VKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVA 565
G G+G + V + G EE + + ++ + A
Sbjct: 1309 ---------GTEGEG---LQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQL 1356
Query: 566 PAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPA 625
E++ G LQ + VQ++ K E+ + EE
Sbjct: 1357 EEIEETGGEGLQEE----------------GVQLEEVKEGPEGGLQGEALEEGLKEEG-- 1398
Query: 626 AMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAP-----RKAGTATSPAGSSP 680
+P+ + + + AS+ P G+Q +AG A+ A + P
Sbjct: 1399 ------------LPEEGSVHGQELSEASS---PDGKGSQEDDPVQEEEAGRAS--ASAEP 1441
Query: 681 AVAGGTQRPAEDSSSSEESD--SEEEKTGLAVTVGQAKSVGKGL--QVKAASVPVKGSLG 736
A GT+ P E S E+D + E ++G + G K G + Q + P +G+
Sbjct: 1442 CPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQPTQGAAE 1501
Query: 737 QGTA--------------PVLPGKT--------GPTVTQVKAE--KQEDSESSEEESDSE 772
+ ++ VL KT V +++A Q++ + ++ +
Sbjct: 1502 RSSSVACSAALDCDPIWVSVLLKKTEKAFLAHLASAVAELRARWGLQDNDLLDQMAAELQ 1561
Query: 773 EAAASPAQ--VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPP 830
+ A Q K ++K Q +A P T G+++ Q + R
Sbjct: 1562 QDVAQRLQDSTKRELQKLQGRAGRMVLEPPREALT----GELLLQTQQRRHRLRG----- 1612
Query: 831 VRNPQ--NSTVLARGPASVPSVGK-AVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQV 887
+RN + L GP S + A++TA +Q G E +E E EA +V
Sbjct: 1613 LRNLSAFSERTLGLGPLSFTLEDEPALSTALGSQLGEE-----AEGEEFCPCEACVRKKV 1667
Query: 888 KPSGKTHQIRAALAPAKES--------PRKG------AAPTPPGK--TGPSAAQAGKQDD 931
P + A P KE+ ++G AA PGK T P++ + + +
Sbjct: 1668 SPMSPKATMGATRGPIKEAFDLQQILQRKRGEHTDGEAAEVAPGKTHTDPTSTRTVQGAE 1727
Query: 932 SG-------SSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTP 984
G + DGE + + DP A A A
Sbjct: 1728 GGLGPGLSQGPGVDEGEDGEGSQRLNRDK---------DPKLGEA-----EGDAMAQERE 1773
Query: 985 RKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSK 1044
K SE++A S E+E E I+ + G S
Sbjct: 1774 GKTHNSETSAGSELGEAEQEG-----------------------EGISERGETGGQGSGH 1810
Query: 1045 ESSRISDGKKQEGPATQVDSAVG--TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1102
E + Q ++A G P S + ++A +P+ + +AP
Sbjct: 1811 EDN------------LQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPE----SEGVEAP 1854
Query: 1103 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPS 1162
E+ D++++ + ED E P+ A P ET E + + AP
Sbjct: 1855 EAEGDAQEAEGEAQPESEDVEAPEAEGEAQ----PESEDVETPEAEWEVQPESEGAEAPE 1910
Query: 1163 QSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK 1222
+A P+ +S ++ + + + +G + + ++AA
Sbjct: 1911 AE-----------------KEAQPETESVEALETEGEDEPESEGAEAQEAEEAA------ 1947
Query: 1223 TGGKEAASGTTPQ----KSRKPKKGAGNPQASTLALQSNI-TQCLLGQPWPLNEAQVQAS 1277
+EA T P+ +S++ ++ A AL+ + TQ G+ P +E V+A
Sbjct: 1948 ---QEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESE-DVEAP 2003
Query: 1278 VVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGE 1337
+ + E+E + D E+ K +++ G+ + + A E E
Sbjct: 2004 EAEGEMQEAEEEAQPESDGV-EAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEE 2062
Query: 1338 ASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAK-DEPEEELQKGMGTVEGGDQ 1396
+ E ++G+A + D +E +G+ S+G + E E E QK G
Sbjct: 2063 EAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGI------ 2116
Query: 1397 SNPKSKKE-KKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKK 1441
P+++ E + +S+ + + + E + +++ +D+E +Q + +
Sbjct: 2117 EAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESE 2162
Score = 38.1 bits (87), Expect = 0.062
Identities = 107/516 (20%), Positives = 176/516 (34%), Gaps = 72/516 (13%)
Query: 508 PASTMGMGPLGKGAGP-------VPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDG-- 558
PAS+ G L +G+ P P V A+PSAQ+G + S E+ DG
Sbjct: 455 PASSTG---LPEGSEPESSCCPRTPEDGVDSASPSAQIGAERKAGGSLGEDPGLCIDGAG 511
Query: 559 ----EVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAG-PVAVQVKAEKPMDNSESSEE 613
E + P G + ++ +G + G P KA +E+S++
Sbjct: 512 LGGPEQGGRLTPRARSEEGASSDSSASTGSHEGSSEWGGRPQGCPGKA-----RAETSQQ 566
Query: 614 SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT 673
+ +PA ++ L+ +T+ + T A+ P+ +G +
Sbjct: 567 EASEGGDPASPALSLSSLRSDDLQ-AETQGQGTEQATGAAVTREPLVLGL----SCSWDS 621
Query: 674 SPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKG 733
A S+P+ +Q+ S + S GL + + K P+
Sbjct: 622 EGASSTPSTCTSSQQGQRRHRSRASAMSSPSSPGLGRVAPRGHPRHSHYR-KDTHSPLDS 680
Query: 734 SLGQ--------------GTAPVLPGKTGPTVTQVKAEKQEDSESSEEESD---SEEAAA 776
S+ + G+ P G + T TQ + S S D + A
Sbjct: 681 SVTKQVPRPPERRRACQDGSVPRYSGSSSSTRTQASGNLRPPSSGSLPSQDLLGTSSATV 740
Query: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVV--TAAAQAKQRSPSKVKPPVRNP 834
+PA V P+A A A +P + T+ + +K + S + P
Sbjct: 741 TPAVHSDFVSGVSPHNAPSAGWAGDAGSRTCSPAPIPPHTSDSCSKSGAASLGEEARDTP 800
Query: 835 QNST--VLARGPASVPSVG---------KAVATAAQAQTGPE-EDSGSSEEESDSEEEAE 882
Q S+ VL G +VG A +AQ GP E S +
Sbjct: 801 QPSSPLVLQVGRPEQGAVGPHRSHCCSQPGTQPAQEAQRGPSPEASWLCGRYCPTPPRGR 860
Query: 883 TLAQVKPS-----GKTHQIRA---ALAPAKESPRKGAAPTPPGKTGPSAAQAGKQ--DDS 932
Q + S G +HQ A +P + + + G P+P +G S + Q
Sbjct: 861 PCPQRRSSSCGSTGSSHQSTARGPGGSPQEGTRQPGPTPSPGPNSGASRRSSASQGAGSR 920
Query: 933 GSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSP 968
G S E++ G P A + P + P SP
Sbjct: 921 GLSEEKTLRSGGGPQGQEEASGVSPSSL---PRSSP 953
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 97.4 bits (241), Expect = 9e-20
Identities = 210/1050 (20%), Positives = 334/1050 (31%), Gaps = 142/1050 (13%)
Query: 140 PHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSS 199
P TG ++ SP + E E EEE G + +S A
Sbjct: 250 PFEPTGSNPSSSAGTPSPEEEEEEEEE----EEEEEEDEEEEEGLSQSISRISETLAGIY 305
Query: 200 SEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPA----------------PG 243
+++ S D +P +P Q + + + + +A A G
Sbjct: 306 DDNSLSQDFPGDESPRPDAQPTQPTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEACREG 365
Query: 244 KVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAA 303
KV G ALPP P +SE E EE P S + + + A
Sbjct: 366 KVSVEVVTAGGAALPPPLL---PPGDSEIEEGEIVQPEEEPRLALSLFRPGGRAARPTPA 422
Query: 304 SAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSE-ESSDSEEETPAAKALLQA 362
A TP P PP + E D E + + + + PAA +
Sbjct: 423 ---ASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWGG 479
Query: 363 KASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE 422
+ + SP APAP GP K +R+ ++ S S
Sbjct: 480 LDLRRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSGT 539
Query: 423 APAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEES 482
PA P+ + S K ++ ++ + + + D R
Sbjct: 540 QPAPPAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRR 599
Query: 483 DSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWE 542
RE + P S G G G K + + G
Sbjct: 600 SRSREKRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGS 659
Query: 543 EDSESSSEESSDSSD---------GEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAG 593
E + + + S S+ G VP ++ + L I + K P+
Sbjct: 660 EKAPAPAPPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPS 719
Query: 594 PVAVQVKAEKPMDNSE--SSEE---SSDSADSEEAPAAMTAAQAKPALKIPQTKACP--- 645
P + + +SE S EE S D + AA +++ ++ K + KA
Sbjct: 720 PAPASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSRE--KGSRRKALDGGD 777
Query: 646 -------KKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEE 698
+ +S K P P+++ ++ P P +G + SSSS
Sbjct: 778 RDRDRDRDRDRDRSSKKARP-------PKESAPSSGPPPKPPVSSG-----SGSSSSSSS 825
Query: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 758
S + K V V + V K A+ GS+G VK +
Sbjct: 826 CSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGLGSIG-----------------VKFSR 868
Query: 759 QEDSES----SEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT 814
+S S +E + +E A A+P K KKT+ KA A + KG
Sbjct: 869 DRESRSPFLKPDERAPTEMAKAAPGSTKP--KKTKVKAKAGAKKTKGTKG---------- 916
Query: 815 AAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE 874
+ PSK + VR+ S G S+ K+ A + G + +EE
Sbjct: 917 ------KTKPSKTRKKVRSGGGS----GGSGGQVSLKKSKADSCSQAAGTK----GAEET 962
Query: 875 SDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAA--QAGKQDDS 932
S S EE P K AL P ++ + TP P A +AG + +
Sbjct: 963 SWSGEERAAKVPSTPPPKAAPPPPALTPDSQTV-DSSCKTPEVSFLPEEATEEAGVRGGA 1021
Query: 933 GSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASES 992
EE + + E + PA T A + AA+ P A ++ S
Sbjct: 1022 EEEEEEEEEEEE------------------EEEEEEQQPATTTATSTAAAAPSTAPSAGS 1063
Query: 993 TARSSSSESEDEDVIPATQCLTPGIRTNV-------VTMPTAHPRIAPKASMAGASSSKE 1045
TA S +E + L P + N+ + A + K A +S +
Sbjct: 1064 TAGDSGAEDGPASRVSQLPTLPPPMPWNLPAGVDCTTSGVLALTALLFKMEEANLASRAK 1123
Query: 1046 SSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLP--EVQQATKAPE 1103
+ + Q + S++G PA P S + ++ L LP P
Sbjct: 1124 AQELIQATNQILSHRKPPSSLGMTPAPVPTSLGLPPGPSSYLLPGSLPLGGCGSTPPTPT 1183
Query: 1104 SSDDSEDSSDSSSGSEEDGEGPQGAKSAHT 1133
+ D + SS SE G+ + K HT
Sbjct: 1184 GLAATSDKREGSSSSEGRGDTDKYLKKLHT 1213
Score = 82.0 bits (201), Expect = 4e-15
Identities = 197/920 (21%), Positives = 313/920 (34%), Gaps = 178/920 (19%)
Query: 601 AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660
A P +S SS S + S +P A PA P+ T + P
Sbjct: 185 APPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAYSPPP-- 242
Query: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRP----AEDSSSSEESDSEEEKTGLAVTVGQAK 716
AP + P GS+P+ + GT P E+ EE + EEE+ GL+ ++ +
Sbjct: 243 ----APEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRIS 298
Query: 717 SVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAA 776
G+ D S ++ +E+
Sbjct: 299 ETLAGIY-------------------------------------DDNSLSQDFPGDESPR 321
Query: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN 836
AQ + T A P + A G + VV A+A + V+
Sbjct: 322 PDAQ---PTQPTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVE-------- 370
Query: 837 STVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE--SDSEEEAETLAQVKPSGKTH 894
V+ G A++P P DS E E EE L+ +P G+
Sbjct: 371 --VVTAGGAALP-----------PPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGRA- 416
Query: 895 QIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDG----------E 944
A+ +P A PT P A +A + DD S ESD +G
Sbjct: 417 --------ARPTPAASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAP 468
Query: 945 APAAVTS-------AQVIKPPLIFVDPNRSPAGPAATPAQAQAASTP--------RKARA 989
AP A S + I RSP+ PA PA A AA P RK
Sbjct: 469 APPAADSRWGGLDLRRKILTQRRERYRQRSPS-PAPAPAPAAAAGPPTRKKSRRERKRSG 527
Query: 990 SESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRI 1049
A SSSS ++ PA+ + R+ P +H + + S S+ + R
Sbjct: 528 EAKEAASSSSGTQPAPPAPASPWDSKKHRSR-DRKPGSHASSSARRRSRSRSRSRSTRRR 586
Query: 1050 S-DGKKQEGPATQVDS---------AVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQAT 1099
S ++ G + + S + PATS S+S + + K R +
Sbjct: 587 SRSTDRRRGGSRRSRSREKRRRRRRSASPPPATSSSSSSRRERHRGKHRD------GGGS 640
Query: 1100 KAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVV 1159
K + S S GSE+ P S T G SR V + + ++ D+
Sbjct: 641 KKKKKRSRSRGEKRSGDGSEK-APAPAPPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDLF 699
Query: 1160 APSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGML 1219
A +++ G + S A ++PK + S + ++ GK K ++ +G
Sbjct: 700 AIKRTITVGRLDKSDPRGPSPAPASSPKRE--VLYDSEGLSGEERGGKSSQKDRRRSGAA 757
Query: 1220 SPKTGGKEAAS--------------------GTTPQKSRKPKKGA---GNPQASTLALQS 1256
S + +E S + +K+R PK+ A G P ++ S
Sbjct: 758 SSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGS 817
Query: 1257 NITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTT--KESSRKGWESRKRKLSG 1314
+ + + + VK+ +++ R+ V TT K+++ G S K S
Sbjct: 818 GSSS---------SSSSCSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGLGSIGVKFSR 868
Query: 1315 DQPAARTPRSKKKKKLGA--GEGGEASVSPEKTSTTSKGKAKRDKAS-GDVKEKKGKGSL 1371
D+ +R+P K ++ + S P+KT +K AK+ K + G K K + +
Sbjct: 869 DR-ESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAKKTKGTKGKTKPSKTRKKV 927
Query: 1372 GSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKD 1431
S G G G GG S KSK + K E+ + + A
Sbjct: 928 RSGG-----------GSGG-SGGQVSLKKSKADSCSQAAGTKGAEETSWSGEERAAKVPS 975
Query: 1432 SESPSQKKKKKKKKTAEQTV 1451
+ P QTV
Sbjct: 976 TPPPKAAPPPPALTPDSQTV 995
Score = 74.3 bits (181), Expect = 8e-13
Identities = 178/938 (18%), Positives = 299/938 (31%), Gaps = 128/938 (13%)
Query: 317 PAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASA 376
PAPP A + AS + + P S S P A T + +
Sbjct: 184 PAPP-PAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEA-YSPP 241
Query: 377 PAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQV 436
PA E P + A + + EE+ + EE D EEE S + +
Sbjct: 242 PAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRISETL 301
Query: 437 R--------AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSR----------SS 478
+ P ESPR A P P QV + + R +
Sbjct: 302 AGIYDDNSLSQDFPGDESPRPDAQPTQPTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEA 361
Query: 479 SEESDSDREALAAMNAAQVKPL---GKS---------PQVKPASTMGM-GPLGKGAGPVP 525
E E + A AA PL G S P+ +P + + P G+ A P P
Sbjct: 362 CREGKVSVEVVTAGGAALPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGRAARPTP 421
Query: 526 PGKVGPAT---PSAQVGKWEEDSESSSEESSDSSDGEV------PTAVAPAQEKSLGNI- 575
P P + E + S + +G + P PA + G +
Sbjct: 422 AASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWGGLD 481
Query: 576 -------------LQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEE 622
Q P+ +PA P AGP + + + E+ E +S S+ ++
Sbjct: 482 LRRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQP 541
Query: 623 APAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAV 682
AP A A P + S P + + R+ + S + S+
Sbjct: 542 APPA---------------PASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRR 586
Query: 683 AGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPV 742
+ T R S S + + + A+ P S
Sbjct: 587 SRSTDRRRGGSRRSRSREKRRRR-----------------RRSASPPPATSSSSSSRRER 629
Query: 743 LPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKT-SVKKTQAKANPAAARAPS 801
GK K +K+ S + D E A +PA + S + A PS
Sbjct: 630 HRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRGAVPPS 689
Query: 802 AKGT----ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA 857
+ + A + +T K P +P+ + S G +
Sbjct: 690 IQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQK 749
Query: 858 AQAQTGPEEDSGSSEEESDSEEEAE----TLAQVKPSGKTHQIRAALAPAKESPRKGAAP 913
+ ++G S SS E+ + + + + + + A P + +P G P
Sbjct: 750 DRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPP 809
Query: 914 TPPGKTGPSAAQAGKQDDS---------------GSSS----EESDSDGEAPAAVTSAQV 954
PP +G ++ + S G SS +++ S G V ++
Sbjct: 810 KPPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGLGSIGVKFSRD 869
Query: 955 IKPPLIFVDPN-RSPAGPA-ATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQC 1012
+ F+ P+ R+P A A P + T KA+A + + +++ +
Sbjct: 870 RESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAKKTKGTKGKTKPSKTRKKVRS 929
Query: 1013 LT-PGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPA 1071
G V++ + +A AG ++E+S + + + P+T A PA
Sbjct: 930 GGGSGGSGGQVSLKKSKADSCSQA--AGTKGAEETSWSGEERAAKVPSTPPPKAAPPPPA 987
Query: 1072 TSPQSTSVQAKGTNKLRKPK---LPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGA 1128
+P S +V + + P+ LPE + E+ + EE+ E Q A
Sbjct: 988 LTPDSQTVDSS----CKTPEVSFLPEEATEEAGVRGGAEEEEEEEEEEEEEEEEEEQQPA 1043
Query: 1129 KSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLL 1166
+ T T TA +S +D A S L
Sbjct: 1044 TTTATSTAAAAPSTAPSAGSTAGDSGAEDGPASRVSQL 1081
Score = 67.4 bits (163), Expect = 1e-10
Identities = 163/752 (21%), Positives = 249/752 (33%), Gaps = 148/752 (19%)
Query: 73 AKKTRVSD--PISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETE 130
+KK R D P S + SS +++T R + + G S +EK +
Sbjct: 552 SKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRR 611
Query: 131 KAGKTGNSMPHPATGKTVANLLS----------GKSPRKSAEPSANTTLVSETEEEGSVP 180
A P PAT + ++ G +K S + E+ P
Sbjct: 612 SAS------PPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAP 665
Query: 181 AFGAAAKPGMVSAGQADSSSEDT--SSSSDETDVEGKPSVKPAQVKASSVSTKESPARKA 238
A G S G DS S D TD + + V S P+
Sbjct: 666 A---PPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAP 722
Query: 239 APAPGKV-----GDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAG---TRSQ 290
A +P + ++ + +GG R + S SS S +A G R +
Sbjct: 723 ASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDR 782
Query: 291 VKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSE 350
+ ++ + A P + P G P PP +G S SSS SS S
Sbjct: 783 DRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSG--------------SGSSSSSSSCSS 828
Query: 351 EETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDS 410
K LQ+K + + +++ PAK+ AA A G G ++ + +
Sbjct: 829 R-----KVKLQSKVAVLIREGVSSTTPAKD-----AASAGLGSIGVKFSRDRESRSPFLK 878
Query: 411 QSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAA-PAPPRK-------TGPA 462
++ + AP KP K +V+A + K KG P+ RK +G +
Sbjct: 879 PDERAPTEMAKAAPGSTKP--KKTKVKAKAGAKKTKGTKGKTKPSKTRKKVRSGGGSGGS 936
Query: 463 AAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAG 522
QV + K + DS S +A A + G+ K ST
Sbjct: 937 GGQVSLKKSKADSCS---------QAAGTKGAEETSWSGEERAAKVPST----------- 976
Query: 523 PVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 582
PP K P P+ DS + E S
Sbjct: 977 --PPPKAAPPPPALTPDSQTVDSSCKTPEVSFL--------------------------- 1007
Query: 583 SPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTK 642
P + V+ AE+ + E EE + + E+ PA TA A P T
Sbjct: 1008 -----PEEATEEAGVRGGAEE--EEEEEEEEEEEEEEEEQQPATTTATSTAAAA--PSTA 1058
Query: 643 ACPKKTNTTASAKVAPVRVGTQAPRKAGTA--TSPAGSSPAVAGGTQRPA-----EDSSS 695
T + A+ P +Q P PAG +G A E+++
Sbjct: 1059 PSAGSTAGDSGAEDGPASRVSQLPTLPPPMPWNLPAGVDCTTSGVLALTALLFKMEEANL 1118
Query: 696 SEESDSEEEKTGLAVTVGQAKSVGKG-LQVKAASVPVKGSLGQGTAP---VLPGK----- 746
+ + ++E L Q S K + PV SLG P +LPG
Sbjct: 1119 ASRAKAQE----LIQATNQILSHRKPPSSLGMTPAPVPTSLGLPPGPSSYLLPGSLPLGG 1174
Query: 747 ---TGPTVTQVKA--EKQEDSESSEEESDSEE 773
T PT T + A +K+E S SSE D+++
Sbjct: 1175 CGSTPPTPTGLAATSDKREGSSSSEGRGDTDK 1206
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 95.9 bits (237), Expect = 3e-19
Identities = 220/949 (23%), Positives = 320/949 (33%), Gaps = 161/949 (16%)
Query: 146 KTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSS 205
K V++L+ + +A + + L T E V A A A V +G S +
Sbjct: 20 KVVSDLVGSLESQLAASAAHHHHLAPRTPE---VRAAAAGALGNHVVSG----SPAGAAG 72
Query: 206 SSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKK 265
+ EG P P A + P PG P V G PPA + +
Sbjct: 73 AGPAAPAEGAPGAAPEPPPAG----RARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRP 128
Query: 266 PEEESESS-------EEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPA 318
P E S S + E APAG A L RA P G PG G P
Sbjct: 129 PPEGSAGSCAPVPAAAAVAAGPEPAPAGPAK--PAGPAALAARAGPGPGPG-PGPGPGPG 185
Query: 319 PPGKAGAVASQTKAGKPE-EDSESSSEESSDSEEETPAAKALLQAKASGKT-----SQVG 372
P AG A+QT G +S ++ + PAA L A+ T VG
Sbjct: 186 PGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVG 245
Query: 373 AASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGK 432
AA+ PA +P AAPAP A A A + ++ P A P+
Sbjct: 246 AAAPPAPAAPSPPAAPAP-------AAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVP 298
Query: 433 APQVRAASAPAKESPRKGAAPAP-PRKTGPAAAQVQVGKQEEDSRSSS--EESDSDREAL 489
P A A+ GAAPAP P GPA Q G + + + R
Sbjct: 299 PP------AAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQ 352
Query: 490 AAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSS 549
AA AAQ L S A++M +GP +GA P P V P P G + + + +
Sbjct: 353 AAPPAAQT--LAASGPASTAASMVIGPTMQGALP-SPAAVPPPAPGTPTGLPKGAAGAVT 409
Query: 550 EESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSE 609
+ S PTA +L PT + P P +Q P
Sbjct: 410 QSLS-----RTPTATTSGIRATL------TPTVLAPRLPQPPQNPTNIQNFQLPPGMVLV 458
Query: 610 SSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGT-QAPRK 668
SE ++A A M A A PQT P+ T++ PV++ T QAP
Sbjct: 459 RSENGQLLMIPQQALAQMQA----QAHAQPQTTMAPRPATPTSA---PPVQISTVQAP-- 509
Query: 669 AGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAAS 728
+P +A S+ + + L + G + G + AS
Sbjct: 510 ---------GTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTAS 560
Query: 729 VPVKGSLGQGTAP-VLPGKT------GPTVTQVKAEKQEDSESSEEESDSEEAAASPAQV 781
+ ++ GT +PG T T+ VK K S + S +++ + A V
Sbjct: 561 LGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANV 620
Query: 782 K----------------TSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPS 825
K TS + ++P P K ++ A ++ +A Q+S
Sbjct: 621 KELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQ 680
Query: 826 KVKPPVRNPQNS-TVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETL 884
+ PP + T + + + GK AT A P +L
Sbjct: 681 QPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPP----------------VLSL 724
Query: 885 AQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGE 944
Q G Q + ++ P+ GA PP T +
Sbjct: 725 TQPTQVGVGKQGQPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNR---------- 774
Query: 945 APAAVTSAQVIK----PPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSE 1000
+T+ Q I+ P+ V P P A + AQAA+ +K + E S +
Sbjct: 775 --IMLTTPQQIQLNPLQPVPVVKPAVLPGTKALSAVSAQAAAA-QKNKLKEPGGGSFRDD 831
Query: 1001 SEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRI 1049
+ DV ASMAG + S+ES+RI
Sbjct: 832 DDINDV----------------------------ASMAGVNLSEESARI 852
Score = 85.1 bits (209), Expect = 4e-16
Identities = 155/640 (24%), Positives = 226/640 (35%), Gaps = 79/640 (12%)
Query: 268 EESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVA 327
+E S+ E + A + + +VRAA+A A G +PA G AGA
Sbjct: 18 DEKVVSDLVGSLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPA--GAAGAGP 75
Query: 328 SQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKG-- 385
+ G P + E PA +A + G G P SPR+
Sbjct: 76 AAPAEGAP-----------GAAPEPPPAGRA----RPGG-----GGPQRPGPPSPRRPLV 115
Query: 386 -AAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAK 444
A PAPP + AG +++ + E AKP+G A A
Sbjct: 116 PAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPG 175
Query: 445 ESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSP 504
P G P P + GP AAQ G S+ +S A A++ P P
Sbjct: 176 PGPGPGPGPGPGKPAGPGAAQTLNG--------SAALLNSHHAAAPAVSLVNNGPAALLP 227
Query: 505 QVKPAST---------MGMGPLGKGAGPVPPGKVGPATP-SAQVGKWEEDSESSSEESSD 554
KPA+ +G A P PP PA P +A + +
Sbjct: 228 LPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHP 287
Query: 555 SSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQ----KAGPVAVQVKAEKPMDNSES 610
+ AV P G A P +PA G P + GP A A P +ES
Sbjct: 288 AGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAA-AAAPAPGVKAES 346
Query: 611 SEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAG 670
+ +A PAA T A + PA T A T A +P V AP G
Sbjct: 347 PKRVVQAA----PPAAQTLAASGPA----STAASMVIGPTMQGALPSPAAVPPPAP---G 395
Query: 671 TATS-PAGSSPAVAGGTQR-PAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAAS 728
T T P G++ AV R P +S + + Q + + Q+
Sbjct: 396 TPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGM 455
Query: 729 VPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
V V+ GQ ++P + + Q++A+ +++ + +A P Q+ T
Sbjct: 456 VLVRSENGQ--LLMIPQQ---ALAQMQAQAHAQPQTTMAPRPATPTSAPPVQIST----V 506
Query: 789 QAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVP 848
QA P AR + I K V+ A Q S + + P PQ ++ G A
Sbjct: 507 QAPGTPIIARQVTPTTII----KQVSQAQTTVQPSATLQRSPGVQPQ---LVLGGAAQTA 559
Query: 849 SVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVK 888
S+G ATA Q T G++ S + E E + + K
Sbjct: 560 SLG--TATAVQTGTPQRTVPGATTTSSAATETMENVKKCK 597
Score = 62.4 bits (150), Expect = 3e-09
Identities = 153/687 (22%), Positives = 217/687 (31%), Gaps = 165/687 (24%)
Query: 432 KAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAA 491
+ P+VRAA+A A + +PA GPAA
Sbjct: 46 RTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAP--------------------------- 78
Query: 492 MNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSE-SSSE 550
A+ P G +P+ PA G G GP PG P P G ++
Sbjct: 79 ---AEGAP-GAAPEPPPAGRARPG----GGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPP 130
Query: 551 ESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAE-------- 602
E S S VP A A A A P +PA GP + AGP A+ +A
Sbjct: 131 EGSAGSCAPVPAAAAVA----------AGPEPAPA-GPAKPAGPAALAARAGPGPGPGPG 179
Query: 603 --------KPMDNSESSEESSDSA--DSEEAPA-AMTAAQAKPALKIPQTKACPKKTNTT 651
KP + + +A +S A A A++ PA +P K P T
Sbjct: 180 PGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPK--PAAPGTV 237
Query: 652 ASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVT 711
P VG AP + PA +PA P + + T
Sbjct: 238 IQT---PPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPA---------------T 279
Query: 712 VGQAKSVGKGLQVKAASVPVK------GSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESS 765
+ + G A +VP GS G AP P GP S
Sbjct: 280 LARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPA-PAAGGPAGV------------S 326
Query: 766 EEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTIS-APGKVVTAAAQAKQRSP 824
+ AAA VK K +A P AA+ +A G S A V+ Q SP
Sbjct: 327 GQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSP 386
Query: 825 SKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETL 884
+ V PP P T L +G A T + ++T
Sbjct: 387 AAVPPPA--PGTPTGLPKGAAGA-------VTQSLSRT---------------------- 415
Query: 885 AQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGE 944
P+ T IRA L P +PR P PP P+ Q + +
Sbjct: 416 ----PTATTSGIRATLTPTVLAPR---LPQPP--QNPTNIQ----------------NFQ 450
Query: 945 APAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDE 1004
P + + L+ + A AQ Q PR A + + S+
Sbjct: 451 LPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPG 510
Query: 1005 DVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDS 1064
I A Q +TP T + + A + P A++ + + + + T
Sbjct: 511 TPIIARQ-VTP--TTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAV 567
Query: 1065 AVGTLPATSPQSTSVQAKGTNKLRKPK 1091
GT T P +T+ + T + K
Sbjct: 568 QTGTPQRTVPGATTTSSAATETMENVK 594
Score = 48.9 bits (115), Expect = 4e-05
Identities = 73/328 (22%), Positives = 108/328 (32%), Gaps = 28/328 (8%)
Query: 792 ANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLAR----GPASV 847
A PAA P +G+ + V AAA A P+ P P LA GP
Sbjct: 120 APPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPA--KPAGPAALAARAGPGPGPG 177
Query: 848 PSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQV------------KPSGKTHQ 895
P G A G + S +S A + KP+
Sbjct: 178 PGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTV 237
Query: 896 IRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVI 955
I+ +P AAP+PP P+A A + + + G T+A +
Sbjct: 238 IQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAV 297
Query: 956 KPPLIFVDPNRSPAGPAATPA---QAQAASTPRKARASESTARSSSSESEDEDVIPATQC 1012
PP + + A PA PA A + P A+ + A +ES V Q
Sbjct: 298 PPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVV----QA 353
Query: 1013 LTPGIRTNVVTMP--TAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLP 1070
P +T + P TA + S + G P + +L
Sbjct: 354 APPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLS 413
Query: 1071 ATSPQSTS-VQAKGTNKLRKPKLPEVQQ 1097
T +TS ++A T + P+LP+ Q
Sbjct: 414 RTPTATTSGIRATLTPTVLAPRLPQPPQ 441
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 95.1 bits (235), Expect = 4e-19
Identities = 191/1197 (15%), Positives = 424/1197 (35%), Gaps = 125/1197 (10%)
Query: 55 QTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEA----EAETAKATPRLASTNS 110
Q ++G E+ A +Q +V+ +++++ +E E E T++ TP++ S +
Sbjct: 163 QNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRN 222
Query: 111 SVLGADLPSSMKEKAKAETEKAGKTGNSMPHP-------------ATGKTVANLLSGKSP 157
A++ E A + +GN GK +N G+
Sbjct: 223 GTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEG 282
Query: 158 RKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPS 217
+ + + + + + + P G S SE+ S+ E + G
Sbjct: 283 QDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDN--GSQR 340
Query: 218 VKPAQV-------KASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEES 270
++ Q + + TKES A GK D ++KG P+ + +E
Sbjct: 341 IEDTQKLNHRESKRVENRITKESETH----AVGKSQDKGIEIKG----PSSGNRNITKEV 392
Query: 271 ESSEEGSESE-EEAPAGTRSQVKASEKILQVRAASAPAK--GTPGKGATPAPPGKAGAVA 327
EG E + + + VK +++ + ++ G T + G +
Sbjct: 393 GKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDS 452
Query: 328 SQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAA 387
+ D +SS+ES+ +++ +++ +S G AS + ES G
Sbjct: 453 YDFDDKSMQGDDPNSSDESNGNDDAN--------SESDNNSSSRGDASYNSDESKDNGNG 504
Query: 388 PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQ-------AKPSGKAPQVRAAS 440
G ++DS S+S+ ++S+ SGK + S
Sbjct: 505 ------------SDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDS 552
Query: 441 APAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDR----EALAAMNAAQ 496
+ S ++ + + + + + DS SS+ SD ++ + +++
Sbjct: 553 DSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSD 612
Query: 497 VKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSS 556
S K S+ + S + + S+S +SSDSS
Sbjct: 613 SSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSS 672
Query: 557 DGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSES-SEESS 615
D ++ + + S + SS + + + ++S+S S SS
Sbjct: 673 DSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSS 732
Query: 616 DSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSP 675
DS+DS + + ++ + + + ++++ S+ + + + ++ S
Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792
Query: 676 AGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSL 735
S + + + ++ S SS+ SDS+ + + + +S GS
Sbjct: 793 DSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSD 852
Query: 736 GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPA 795
+ + + + DS S + ++S ++ S +S + +N +
Sbjct: 853 SDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS 912
Query: 796 AARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVA 855
+ + S+ + S+ + + + S S + NS+ + S S +
Sbjct: 913 DS-SDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNS-----S 966
Query: 856 TAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP 915
++ + + DS +S + SDS + +++ S + ++ S ++ +
Sbjct: 967 DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSS----DSSDSSNSSDSS 1022
Query: 916 PGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATP 975
+++ + DS SS+ SDS + ++ +S + + + +
Sbjct: 1023 NSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1082
Query: 976 AQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKA 1035
+ ++ + + +S+S+ S SS+S D + +
Sbjct: 1083 ESSDSSDSSNSSDSSDSSDSSDSSDSSDS---------------------------SDSS 1115
Query: 1036 SMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEV 1095
+ +S+S +SS SD + DS+ + + S S+ + ++ +
Sbjct: 1116 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSD-SSDSSDSSDSSDSSDS 1174
Query: 1096 QQATKAPESSD--DSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAES 1153
++ + +SSD DS DSSDSS S+ S + + +++ + ES
Sbjct: 1175 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNES 1234
Query: 1154 SEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEA 1210
S+ + S S +S ++ DSS S ST + D+ D + ++
Sbjct: 1235 SDSSDSSDS----------------SDSSNSSDSSDSSDSSDSTSDSNDESDSQSKS 1275
Score = 87.8 bits (216), Expect = 7e-17
Identities = 139/876 (15%), Positives = 318/876 (36%), Gaps = 48/876 (5%)
Query: 74 KKTRVSDPISTSESS-EEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKA 132
K + DP S+ ES+ ++ +E++ ++ AS NS K+ K
Sbjct: 458 KSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSD--------ESKDNGNGSDSKG 509
Query: 133 GKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVS 192
+ +S T + +N +G + + S + S++ + S + ++ S
Sbjct: 510 AEDDDSDSTSDTNNSDSNG-NGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSD-----S 563
Query: 193 AGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQV 252
+ +DS S D++SSSD + S + S ++ +S + D +
Sbjct: 564 SDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSK 623
Query: 253 KGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPG 312
+ + + + S S+S + + + S S +S + +
Sbjct: 624 SDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDS 683
Query: 313 KGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVG 372
++ + + +S++ DS+SS +SSDS + + S +S
Sbjct: 684 SNSSDSSDSSDSSNSSESSDSSDSSDSDSS--DSSDSSNSNSSDSDSSNSSDSSDSSNSS 741
Query: 373 AASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGK 432
+S + S ++ + + + DS +SS+ +DS + + +
Sbjct: 742 DSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSS 801
Query: 433 APQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALA-A 491
+ S+ + +S ++ + ++ DS SS+ SDSD + +
Sbjct: 802 DSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS 861
Query: 492 MNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESS--- 548
N++ S +S + + S+ + S+SS
Sbjct: 862 SNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS 921
Query: 549 -SEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDN 607
S ESS+SSD + + + + S + SS + + N
Sbjct: 922 DSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN 981
Query: 608 SESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPR 667
S S +SSDS+DS ++ + ++ + + + +N++ S+ + + +
Sbjct: 982 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD 1041
Query: 668 KAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAA 727
+ ++ S S + + + ++ S SS+ SDS + + S +
Sbjct: 1042 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD 1101
Query: 728 SVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKK 787
S + + + DS +S + SDS +++ S +S
Sbjct: 1102 S----------------SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSS 1145
Query: 788 TQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASV 847
++++ ++ + S+ + S+ + ++ + S S + +S+ + S
Sbjct: 1146 DSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1205
Query: 848 PSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESP 907
S ++ + + DS S + SDS E +++ S ++ + + +S
Sbjct: 1206 DSSD----SSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNS-----SDSSDSS 1256
Query: 908 RKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDG 943
+ + S +++G +++GS S +SDS+G
Sbjct: 1257 DSSDSTSDSNDESDSQSKSGNGNNNGSDS-DSDSEG 1291
Score = 80.1 bits (196), Expect = 1e-14
Identities = 212/1328 (15%), Positives = 441/1328 (33%), Gaps = 110/1328 (8%)
Query: 155 KSPRKSAEPSANTTLV--SETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDV 212
K + E S N L+ S + + A G + G++ + D ++ + + +
Sbjct: 22 KPLERHVEKSMNLHLLARSNVSVQDELNASGTIKESGVL-VHEGDRGRQENTQDGHKGEG 80
Query: 213 EGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESES 272
G K A+V S ST + A + G GD K E
Sbjct: 81 NGS---KWAEVGGKSFSTYSTLANEEGNIEGWNGDTG---------------KAETYGHD 122
Query: 273 SEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKA 332
G E E G + QV + A + T G G G
Sbjct: 123 GIHGKE-ENITANGIQGQVSIIDN-----AGATNRSNTNGNTDKNTQNGDVGDAGHNEDV 176
Query: 333 GKPEEDSE--SSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP 390
+ED + S S+D+E+E + S T Q+ + KE+
Sbjct: 177 AVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGED 236
Query: 391 PGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKG 450
G + + G E++ + S D E+E K S + + KE
Sbjct: 237 AGLDNSDGSPSGNGADEDEDEGSG---DDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDS 293
Query: 451 AAPA---------PPRKTGP--AAAQVQVGKQEEDSRSSSEESDSDR-EALAAMNAAQVK 498
+ P K P + K EE+S E++ S R E +N + K
Sbjct: 294 SIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESK 353
Query: 499 PLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSE------ES 552
+ ++ K + T +G + G + +VGK E E + +
Sbjct: 354 RV-ENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKG 412
Query: 553 SDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQ-VKAEKPMDNSESS 611
+ + GEV P Q+ GN + T S + + + ++ + P + ES+
Sbjct: 413 NVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESN 472
Query: 612 -----EESSDSADSEEAPAAMTAAQAKPALKIPQTKACP-----KKTNTTASAKVAPVRV 661
SD+ S A+ + ++K +K ++T S
Sbjct: 473 GNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNN 532
Query: 662 GTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKG 721
G K+ + + SS + + + + DSS S +SDS + + + S
Sbjct: 533 GNDDNDKSDSGKGKSDSSDSDSSDSSN-SSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSS 591
Query: 722 LQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQV 781
+ S S + ++ + S+SS+ +SDS ++ + +
Sbjct: 592 DSDSSDSSNSSDSSDSSDS---------------SDSSDSSDSSDSKSDSSKSESDSSDS 636
Query: 782 KTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLA 841
+ + + ++ ++ + S+ + S+ + ++ + S S + +S+ +
Sbjct: 637 DSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS 696
Query: 842 RGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALA 901
S S + + ++ + +S SS+ +S + ++ + S + +
Sbjct: 697 NSSESSDSSDSSDSDSSDSSDS--SNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSD 754
Query: 902 PAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIF 961
+ S ++ + ++ + DS SS SDS + ++ +S
Sbjct: 755 SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS---------- 804
Query: 962 VDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNV 1021
N S + ++ + + ++++ + +S+S+ S+SS+S D R++
Sbjct: 805 ---NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSD- 860
Query: 1022 VTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQA 1081
+ + + +S+S +SS SD + + DS+ + +S S S +
Sbjct: 861 ------SSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDS 914
Query: 1082 K-GTNKLRKPKLPEVQQATKAPESSD--DSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPT 1138
+N + + + +SS+ DS DSSDSS+ S+ S + +
Sbjct: 915 SDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSS 974
Query: 1139 PSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTL 1198
S + +++ S D S S S + ++S S + S + S +
Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 1034
Query: 1199 AAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNI 1258
+ D D + ++ S + +++ + S + + ++S + SN
Sbjct: 1035 DSSDSSDSSDSSDSSDSSDS-SNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNS 1093
Query: 1259 TQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPA 1318
+ + +S ++ + + +SS S S +
Sbjct: 1094 SDS------SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDS 1147
Query: 1319 ARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKD 1378
+ + S S +S +S D + S S +
Sbjct: 1148 SESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1207
Query: 1379 EPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQK 1438
+ + + D S+ E S + + + + DS S S
Sbjct: 1208 SDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSND 1267
Query: 1439 KKKKKKKT 1446
+ + K+
Sbjct: 1268 ESDSQSKS 1275
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 91.3 bits (225), Expect = 6e-18
Identities = 234/1163 (20%), Positives = 415/1163 (35%), Gaps = 160/1163 (13%)
Query: 188 PGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGD 247
P V+ +S+ ++ + VE + V+ ++VS + PA + APAP + +
Sbjct: 1639 PPSVTVVTLESAPSALEKTTGDKTVEAPLVTEEKTVEPATVSEEAKPASEPAPAPVEQLE 1698
Query: 248 VTPQVKGGALPPAKRAKKPE--EESESSEEGSESEEEAPAGTRSQVKASEKI----LQVR 301
+ GA P + A P EE S ++ + + P S +A + +
Sbjct: 1699 QV-DLPPGADPDKEAAMMPAGVEEGSSGDQPPYLDAKPPTPGASFSQAESNVDPEPDSTQ 1757
Query: 302 AASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAA---KA 358
S PA+ + A A A A K E ES S D E + P A K
Sbjct: 1758 PLSKPAQKSEEANEPKAEKPDATADAEPDANQKAEAAPESQPPASEDLEVDPPVAAKDKK 1817
Query: 359 LLQAKASGKTSQVGAASAPAKESPRKG---------AAPAPPGKTGPAVAKAQAGKREED 409
++K S Q A S K RK + +P G+ + ++
Sbjct: 1818 PNKSKRSKTPVQAAAVSIVEKPVTRKSERIDREKLKRSNSPRGEAQKLLELKMEAEKITR 1877
Query: 410 SQSSSEESDSEEEAPAQAKPSGKAPQVRAASA---------PAK---ESPR--------- 448
+ S + +D E P+ + VR+ A P K E PR
Sbjct: 1878 TASKNSAADLEHPEPSLPLSRTRRRNVRSVYATMGDHENRSPVKEPVEQPRVTRKRLERE 1937
Query: 449 ---KGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEES----DSDREALAAMNAAQVKPLG 501
A P PR+ P + + ++EE+ E+ + R + AA P G
Sbjct: 1938 LQEAAAVPTTPRRGRPPKTRRRADEEEENEAKEPAETLKPPEGWRSPRSQKTAAGGGPQG 1997
Query: 502 K----SPQV---KPASTMGMGP-LGKGAGPVPPGKVGPATPSAQVGKWEE---------- 543
K P+V +P +T +GP +G + P S Q ++
Sbjct: 1998 KKGKNEPKVDATRPEATTEVGPQIGVKESSMEPKAAEEEAGSEQKRDRKDAGTDKNPPET 2057
Query: 544 ------DSESSSEESSDSSDGEVPTA-VAPAQEKSLGNILQA-KPTSSPAKGPPQKAGPV 595
+ + + E++S S G + +A + SL N+ A P + A+ +++G V
Sbjct: 2058 APVEVVEKKPAPEKNSKSKRGRSRNSRLAVDKSASLKNVDAAVSPRGAAAQAGERESGVV 2117
Query: 596 AVQ-VKAEKPM-DNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTAS 653
AV K+E P ++ SS+ SD D ++ P + + P+ P+ K+ +
Sbjct: 2118 AVSPEKSESPQKEDGLSSQLKSDPVDPDKEPEKEDVSASGPS---PEATQLAKQMELEQA 2174
Query: 654 AKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVG 713
+ ++ + A A +P G +P +PA +S +E LA +G
Sbjct: 2175 VEHI-AKLAEASASAAYKADAPEGLAPE---DRDKPAHQASETE----------LAAAIG 2220
Query: 714 QAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQE---------DSES 764
S+ + + + P + L G Q E E ++E+
Sbjct: 2221 ---SIINDISGEPENFPAPPPYPGESQTDLQPPAGAQALQPSEEGMETDEAVSGILETEA 2277
Query: 765 SEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISA--------PGKVVTAA 816
+ E S A P+ T K+ + ++ + P AKG+ G+ T
Sbjct: 2278 ATESSRPPVNAPDPSAGPTDTKEARGNSSETSHSVPEAKGSKEVEVTLVRKDKGRQKTTR 2337
Query: 817 AQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESD 876
++ K+ + KV PV + + A+G + + G T Q P+E+ S + S
Sbjct: 2338 SRRKRNTNKKVVAPVESHVPESNQAQGESPAANEG----TTVQHPEAPQEEKQSEKPHST 2393
Query: 877 SEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAP---TPPGKTGP--SAAQAGKQDD 931
+ + PS T ++ + +P K + P PP + P QA +
Sbjct: 2394 PPQSCTSDLSKIPS--TENSSQEISVEERTPTKASVPPDLPPPPQPAPVDEEPQARFRVH 2451
Query: 932 SGSSSE--ESDSDGEAP----AAVTSAQVIKPPLIFVDPNRSPAGPA----ATPAQAQAA 981
S S+ SD P +VT+A++ P P++SP + +A
Sbjct: 2452 SIIESDPVTPPSDPSIPIPTLPSVTAAKLSPPVASGGIPHQSPPTKVTEWITRQEEPRAQ 2511
Query: 982 STPRKARASESTARSSSSESE-------DEDVIPATQCLTPGIRTNVVTMPTAHPRI--A 1032
STP A ++ A + S D + AT + + T + +A P + A
Sbjct: 2512 STPSPALPPDTKASDVDTSSSTLRKILMDPKYVSATSVTSTSVTTAIAEPVSAAPCLHEA 2571
Query: 1033 PKASMAGASSSKESSRISDGKKQEGPATQVDSAVG---TLPATSPQSTSVQAKGTNKLRK 1089
P + +E + E A++V A P +P+ TSV ++ +
Sbjct: 2572 PPPPVDSKKPLEEKTAPPVTNNSEIQASEVLVAADKEKVAPVIAPKITSVISRMPVSIDL 2631
Query: 1090 PKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEET 1149
++ A AP++ + S G + L GP TL
Sbjct: 2632 ENSQKITLAKPAPQTL--------TGLVSALTGLVNVSLVPVNALKGPVKGSVTTLKSLV 2683
Query: 1150 AAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQE 1209
+ + +V+ ++L+G + TP N+ + T+ A
Sbjct: 2684 STPAGPVNVLKGPVNVLTGPVNVLTTPVNATVGTVN-------AAPGTVNAAASAVNATA 2736
Query: 1210 AKPQQAAGMLSPKTGGKEAASGT 1232
+ AG ++ +GG A +GT
Sbjct: 2737 SAVTVTAGAVTAASGGVTATTGT 2759
Score = 78.6 bits (192), Expect = 4e-14
Identities = 189/949 (19%), Positives = 331/949 (34%), Gaps = 158/949 (16%)
Query: 405 KREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAA 464
++E++ +E + +E+ K AP+ + + S + ++ P+A
Sbjct: 1595 QKEKEKDQKPKEVEKQEDTENHPKTPESAPENKDSELKTPPSVGPPSVTVVTLESAPSAL 1654
Query: 465 QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGK-GAGP 523
+ G + ++ +EE V+P S + KPAS P+ +
Sbjct: 1655 EKTTGDKTVEAPLVTEEK-------------TVEPATVSEEAKPASEPAPAPVEQLEQVD 1701
Query: 524 VPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSS 583
+PPG P +A + E E SS + D + PT A + N+ ++
Sbjct: 1702 LPPG-ADPDKEAAMMPAGVE--EGSSGDQPPYLDAKPPTPGASFSQAE-SNVDPEPDSTQ 1757
Query: 584 PAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADS--EEAPAAMTAAQAKPALKIPQT 641
P P QK+ A + KAEKP +++ +++ A++ E P A + P +
Sbjct: 1758 PLSKPAQKS-EEANEPKAEKPDATADAEPDANQKAEAAPESQPPASEDLEVDPPVAAKDK 1816
Query: 642 KACPKKTNTT----ASAKVAPVRVGTQAPR----KAGTATSPAGSSPAVAG---GTQRPA 690
K K + T A+ + V ++ R K + SP G + + ++
Sbjct: 1817 KPNKSKRSKTPVQAAAVSIVEKPVTRKSERIDREKLKRSNSPRGEAQKLLELKMEAEKIT 1876
Query: 691 EDSSSSEESDSEEEKTGLAVTVGQ---AKSVGKGLQVKAASVPVKGSLGQ---------- 737
+S + +D E + L ++ + +SV + PVK + Q
Sbjct: 1877 RTASKNSAADLEHPEPSLPLSRTRRRNVRSVYATMGDHENRSPVKEPVEQPRVTRKRLER 1936
Query: 738 -----GTAPVLPGKTGPTVTQVKAEKQEDSESSE--EESDSEEAAASPAQVKTS------ 784
P P + P T+ +A+++E++E+ E E E SP KT+
Sbjct: 1937 ELQEAAAVPTTPRRGRPPKTRRRADEEEENEAKEPAETLKPPEGWRSPRSQKTAAGGGPQ 1996
Query: 785 --------------------------VKKTQAKANPAAARAPSAK-------GTISAPGK 811
VK++ + A A S + GT P +
Sbjct: 1997 GKKGKNEPKVDATRPEATTEVGPQIGVKESSMEPKAAEEEAGSEQKRDRKDAGTDKNPPE 2056
Query: 812 VVTAAAQAKQRSPSKVKPPVR-NPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSG- 869
K+ +P K R +NS + AS+ +V AV+ A E +SG
Sbjct: 2057 TAPVEVVEKKPAPEKNSKSKRGRSRNSRLAVDKSASLKNVDAAVSPRGAAAQAGERESGV 2116
Query: 870 --SSEEESDSEEEAETLAQVKPSGKTHQIRA-ALAPAKESPRKGAAPTPPGKTGPSAAQA 926
S E+S+S + K G + Q+++ + P KE ++ + + P P A Q
Sbjct: 2117 VAVSPEKSESPQ--------KEDGLSSQLKSDPVDPDKEPEKEDVSASGP---SPEATQL 2165
Query: 927 GKQ--------------DDSGSSSEESDS-------DGEAPAAVTSAQVIKPPL--IFVD 963
KQ + S S++ ++D+ D + PA S + + I D
Sbjct: 2166 AKQMELEQAVEHIAKLAEASASAAYKADAPEGLAPEDRDKPAHQASETELAAAIGSIIND 2225
Query: 964 PNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVT 1023
+ P A P + T + A + S E ++ + + T T
Sbjct: 2226 ISGEPENFPAPPPYPGESQTDLQPPAGAQALQPSEEGMETDEAVSGI------LETEAAT 2279
Query: 1024 MPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKG 1083
+ P AP S AG + +KE+ S P + V + +
Sbjct: 2280 ESSRPPVNAPDPS-AGPTDTKEARGNSSETSHSVPEAKGSKEVEVTLVRKDKGRQKTTRS 2338
Query: 1084 TNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSE-EDGEGPQGAK-SAHTLVGPTPSR 1141
K K + PES+ +S ++ G+ + E PQ K S P S
Sbjct: 2339 RRKRNTNKKVVAPVESHVPESNQAQGESPAANEGTTVQHPEAPQEEKQSEKPHSTPPQSC 2398
Query: 1142 TETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSV------- 1194
T L + + E+S ++ ++ + P L P A +D P
Sbjct: 2399 TSDLSKIPSTENSSQEISVEERTPTKASVPPDLPPPPQPA-----PVDEEPQARFRVHSI 2453
Query: 1195 --SSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPK 1241
S + DP P A LSP ASG P +S K
Sbjct: 2454 IESDPVTPPSDPSIPIPTLPSVTAAKLSP-----PVASGGIPHQSPPTK 2497
Score = 77.4 bits (189), Expect = 9e-14
Identities = 211/1012 (20%), Positives = 350/1012 (34%), Gaps = 141/1012 (13%)
Query: 62 KRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKA--------TPRLASTNSS-- 111
+R+ +E AA+ R P + + EEEE E A+ +PR T +
Sbjct: 1935 ERELQEAAAVPTTPRRGRPPKTRRRADEEEENEAKEPAETLKPPEGWRSPRSQKTAAGGG 1994
Query: 112 ---VLGADLPSSMKEKAKAETEKAGKTG---NSMPHPATGKTVANLLSGKSPRKSAEPSA 165
G + P + +A TE + G +SM A + + K RK A
Sbjct: 1995 PQGKKGKNEPKVDATRPEATTEVGPQIGVKESSMEPKAAEEEAGS--EQKRDRKDAGTDK 2052
Query: 166 NT--TLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQV 223
N T E E+ P + +K G + + D S+S D P AQ
Sbjct: 2053 NPPETAPVEVVEKKPAPEKNSKSKRGR---SRNSRLAVDKSASLKNVDAAVSPRGAAAQA 2109
Query: 224 -KASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEE 282
+ S SP + +P K ++ Q+K + P K +PE+E S+ G E
Sbjct: 2110 GERESGVVAVSPEKSESPQ--KEDGLSSQLKSDPVDPDK---EPEKEDVSAS-GPSPEAT 2163
Query: 283 APAGTRSQVKASEKILQVRAASAPA--KGTPGKGATPAPPGKAGAVASQTK--------- 331
A +A E I ++ ASA A K +G P K AS+T+
Sbjct: 2164 QLAKQMELEQAVEHIAKLAEASASAAYKADAPEGLAPEDRDKPAHQASETELAAAIGSII 2223
Query: 332 ---AGKPEE-DSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAA 387
+G+PE + S ++ + PA LQ G + + E+ + +
Sbjct: 2224 NDISGEPENFPAPPPYPGESQTDLQPPAGAQALQPSEEGMETDEAVSGILETEAATESSR 2283
Query: 388 P---APPGKTGPAVAKAQAGKREEDSQSSSEESDSEE----------------------- 421
P AP GP K G E S S E S+E
Sbjct: 2284 PPVNAPDPSAGPTDTKEARGNSSETSHSVPEAKGSKEVEVTLVRKDKGRQKTTRSRRKRN 2343
Query: 422 -----------EAPAQAKPSGKAPQVR-AASAPAKESPRKGAAPAPPRKTGPAAAQVQVG 469
P + G++P + E+P++ P T P + +
Sbjct: 2344 TNKKVVAPVESHVPESNQAQGESPAANEGTTVQHPEAPQEEKQSEKPHSTPPQSCTSDLS 2403
Query: 470 KQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV--KPASTMGMGPLGKGAGPVPPG 527
K SS E S +R A + P + V +P + + + + + PV P
Sbjct: 2404 KIPSTENSSQEISVEERTPTKASVPPDLPPPPQPAPVDEEPQARFRVHSIIE-SDPVTP- 2461
Query: 528 KVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEK---SLGNILQAKPTSSP 584
P+ PS + S ++++ S + G +P P + + +A+ T SP
Sbjct: 2462 ---PSDPSIPIPTLP--SVTAAKLSPPVASGGIPHQSPPTKVTEWITRQEEPRAQSTPSP 2516
Query: 585 AKGPPQKAGPVAVQVKA-------EKPMDNSESSEESSDSADSEEAPAAMTAAQAKP--- 634
A P KA V K + + + S +A +E AA +A P
Sbjct: 2517 ALPPDTKASDVDTSSSTLRKILMDPKYVSATSVTSTSVTTAIAEPVSAAPCLHEAPPPPV 2576
Query: 635 -ALKIPQTKACPKKTNTT---ASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPA 690
+ K + K P TN + AS + AP A TS P +
Sbjct: 2577 DSKKPLEEKTAPPVTNNSEIQASEVLVAADKEKVAPVIAPKITSVISRMPV--------S 2628
Query: 691 EDSSSSEE----SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQ--------- 737
D +S++ + + TGL + +V + V A PVKGS+
Sbjct: 2629 IDLENSQKITLAKPAPQTLTGLVSALTGLVNVSL-VPVNALKGPVKGSVTTLKSLVSTPA 2687
Query: 738 GTAPVLPGK----TGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKAN 793
G VL G TGP + AA++ ++V T
Sbjct: 2688 GPVNVLKGPVNVLTGPVNVLTTPVNATVGTVNAAPGTVNAAASAVNATASAVTVTAGAVT 2747
Query: 794 PAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKA 853
A+ + GT++ G V+ + + KQR+ + +P + V+ PA G
Sbjct: 2748 AASGGVTATTGTVTMAGAVIAPSTKCKQRASANENSRF-HPGSMPVIDDRPA---DAGSG 2803
Query: 854 VATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKP-SGKTHQIRAALAPAKESPRKGAA 912
G S S ++ + + ++Q+ P S + + +++ ++ P A
Sbjct: 2804 AGLRVNTSEGVVLLSYSGQKTEGPQRISAKISQIPPASAMDIEFQQSVSKSQVKPDSVTA 2863
Query: 913 PTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDP 964
PP K GP A + S+ + A ++S + +P L +P
Sbjct: 2864 SQPPSK-GPQAPAGYANVATHSTLVLTAQTYNASPVISSVKADRPSLEKPEP 2914
Score = 56.6 bits (135), Expect = 2e-07
Identities = 99/475 (20%), Positives = 176/475 (37%), Gaps = 49/475 (10%)
Query: 1000 ESEDEDVIPATQCLTPGIR-TNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGP 1058
+ ED + P T P + + + T P+ P ++ A S+ E + + K E P
Sbjct: 1609 KQEDTENHPKTPESAPENKDSELKTPPSVGPPSVTVVTLESAPSALEKT--TGDKTVEAP 1666
Query: 1059 ATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGS 1118
+ V P + S +AK ++ + +++Q P +D ++++ +G
Sbjct: 1667 LVTEEKTV------EPATVSEEAKPASEPAPAPVEQLEQVD-LPPGADPDKEAAMMPAGV 1719
Query: 1119 EEDGEGPQ-----------GAK--SAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSL 1165
EE G Q GA A + V P P T+ L + A +S E + +
Sbjct: 1720 EEGSSGDQPPYLDAKPPTPGASFSQAESNVDPEPDSTQPL-SKPAQKSEEANEPKAEKPD 1778
Query: 1166 LSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAK--PQQAAGML---S 1220
+ P A ++ P V +AAKD K + P QAA +
Sbjct: 1779 ATADAEPDANQKAEAAPESQPPASEDLEVDPPVAAKDKKPNKSKRSKTPVQAAAVSIVEK 1838
Query: 1221 PKTGGKEAASGTTPQKSRKPKKGAGN--------PQASTLALQSNITQCLLGQP-WPLNE 1271
P T E ++S P+ A + + A +++ +P PL+
Sbjct: 1839 PVTRKSERIDREKLKRSNSPRGEAQKLLELKMEAEKITRTASKNSAADLEHPEPSLPLSR 1898
Query: 1272 AQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRS----KKK 1327
+ + +V V + + E + V E R + +R+L TPR K +
Sbjct: 1899 TR-RRNVRSVYATMGDHENRSPVKEPVEQPRVTRKRLERELQEAAAVPTTPRRGRPPKTR 1957
Query: 1328 KKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKG 1387
++ E EA E ++ R + K G G G +G K+EP+ + +
Sbjct: 1958 RRADEEEENEAKEPAETLKPPEGWRSPRSQ-----KTAAGGGPQGKKG-KNEPKVDATRP 2011
Query: 1388 MGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKK 1442
T E G Q K + K+ + + E+K +K A +P + +KK
Sbjct: 2012 EATTEVGPQIGVKESSMEPKAAEEEAGSEQKRDRKDAGTDKNPPETAPVEVVEKK 2066
Score = 56.2 bits (134), Expect = 2e-07
Identities = 171/897 (19%), Positives = 296/897 (32%), Gaps = 103/897 (11%)
Query: 586 KGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP 645
K QK V Q E ES+ E+ DS + + P+ P++ + ++ P
Sbjct: 1598 KEKDQKPKEVEKQEDTENHPKTPESAPENKDS-ELKTPPSV-----GPPSVTVVTLESAP 1651
Query: 646 KKTNTTASAKVAPVRVGTQA----PRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDS 701
T K + T+ P PA S PA A Q D + D
Sbjct: 1652 SALEKTTGDKTVEAPLVTEEKTVEPATVSEEAKPA-SEPAPAPVEQLEQVDLPPGADPDK 1710
Query: 702 EEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQED 761
E V G + L K + S + P T P A+K E+
Sbjct: 1711 EAAMMPAGVEEGSSGDQPPYLDAKPPTPGASFSQAESNVDPEPDSTQPL--SKPAQKSEE 1768
Query: 762 SESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQ 821
+ + E A A P AN A AP ++ S +V A AK
Sbjct: 1769 ANEPKAEKPDATADAEP------------DANQKAEAAPESQPPASEDLEVDPPVA-AKD 1815
Query: 822 RSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEA 881
+ P+K K Q + V S+ + T + E+ S+ ++++
Sbjct: 1816 KKPNKSKRSKTPVQAAAV---------SIVEKPVTRKSERIDREKLKRSNSPRGEAQKLL 1866
Query: 882 ETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDS 941
E + + +T +A P + T A G ++ E +
Sbjct: 1867 ELKMEAEKITRTASKNSAADLEHPEPSLPLSRTRRRNVRSVYATMGDHENRSPVKEPVEQ 1926
Query: 942 DG-----------EAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARAS 990
EA A T+ + +PP + A PA+ ++ S
Sbjct: 1927 PRVTRKRLERELQEAAAVPTTPRRGRPPKTRRRADEEEENEAKEPAETLKPPEGWRSPRS 1986
Query: 991 ESTARSSSSESEDEDVIPATQCLTPGIRTNV-VTMPTAHPRIAPKASMAGASSSKESSRI 1049
+ TA + + P P T V + + PKA+ A S ++ R
Sbjct: 1987 QKTAAGGGPQGKKGKNEPKVDATRPEATTEVGPQIGVKESSMEPKAAEEEAGSEQKRDRK 2046
Query: 1050 SDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSE 1109
G + P T V PA S S + + N +L + A+ + S
Sbjct: 2047 DAGTDKNPPETAPVEVVEKKPAPEKNSKSKRGRSRNS----RLAVDKSASLKNVDAAVSP 2102
Query: 1110 DSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGY 1169
+ + +G E G +V +P ++E+ +E S L S
Sbjct: 2103 RGAAAQAGERESG-----------VVAVSPEKSESPQKEDGLSSQ----------LKSDP 2141
Query: 1170 MTPGLTPANSQASKATPKLDSSPSVSSTLAAKD---DPDGKQEAKPQQAAGMLSPKTGGK 1226
+ P P S S PS +T AK + + AK +A+ + K
Sbjct: 2142 VDPDKEPEKEDVSA------SGPSPEATQLAKQMELEQAVEHIAKLAEASASAAYKA--- 2192
Query: 1227 EAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPW-----PLNEAQVQASVVKV 1281
+A G P+ KP A + + A +I + G+P P + Q +
Sbjct: 2193 DAPEGLAPEDRDKPAHQASETELA--AAIGSIINDISGEPENFPAPPPYPGESQTDLQPP 2250
Query: 1282 LTELLEQERKKVVDTTKESS-----RKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGG 1336
Q ++ ++T + S ES + ++ P+A P K+ + + E
Sbjct: 2251 AGAQALQPSEEGMETDEAVSGILETEAATESSRPPVNAPDPSAG-PTDTKEARGNSSETS 2309
Query: 1337 ----EASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTV- 1391
EA S E T + R K + +++ + + PE +G
Sbjct: 2310 HSVPEAKGSKEVEVTLVRKDKGRQKTTRSRRKRNTNKKVVAPVESHVPESNQAQGESPAA 2369
Query: 1392 -EGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTA 1447
EG +P++ +E+K+S+K + +K ST++S +++ K +
Sbjct: 2370 NEGTTVQHPEAPQEEKQSEKPHSTPPQSCTSDLSKIPSTENSSQEISVEERTPTKAS 2426
Score = 43.5 bits (101), Expect = 0.001
Identities = 88/327 (26%), Positives = 129/327 (39%), Gaps = 47/327 (14%)
Query: 1046 SSRISDGKKQEGPATQVDSA---VGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQAT--- 1099
S RI + EG + DS V + + T +Q K K +KPK E Q+ T
Sbjct: 1557 SGRIYGKQTSEGANSTTDSIQEPVVLFHSRFMELTRMQQKEKEKDQKPKEVEKQEDTENH 1616
Query: 1100 -KAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEE--TAAESSED 1156
K PES+ +++DS + S VGP PS T +E +A E +
Sbjct: 1617 PKTPESAPENKDSELKTPPS----------------VGP-PSVTVVTLESAPSALEKTTG 1659
Query: 1157 D--VVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQ 1214
D V AP L++ T + PA + + +A P + +P+ L D P G A P +
Sbjct: 1660 DKTVEAP---LVTEEKT--VEPA-TVSEEAKPASEPAPAPVEQLEQVDLPPG---ADPDK 1710
Query: 1215 AAGMLSPKTGGKEAASGTTPQ--KSRKPKKGAGNPQA-STLALQSNITQCLLGQPWPLNE 1271
A M+ G +E +SG P ++ P GA QA S + + + TQ L E
Sbjct: 1711 EAAMM--PAGVEEGSSGDQPPYLDAKPPTPGASFSQAESNVDPEPDSTQPLSKPAQKSEE 1768
Query: 1272 AQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLG 1331
A + T E + + + ES E L D P A + K K
Sbjct: 1769 ANEPKAEKPDATADAEPDANQKAEAAPESQPPASED----LEVDPPVAAKDKKPNKSKRS 1824
Query: 1332 AGEGGEASVS-PEKTSTTSKGKAKRDK 1357
A+VS EK T + R+K
Sbjct: 1825 KTPVQAAAVSIVEKPVTRKSERIDREK 1851
Score = 39.7 bits (91), Expect = 0.021
Identities = 91/415 (21%), Positives = 149/415 (35%), Gaps = 79/415 (19%)
Query: 54 QQTSELGRKRKAEEDAA-LQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSV 112
++ L RK K E+D Q +K +V P +S+SSE ++E E E + PR +
Sbjct: 803 ERERRLIRKEKVEKDKTDKQKRKGKVHSP--SSQSSETDQENEREQSPEKPRSCN----- 855
Query: 113 LGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSE 172
K EKA K G + R P T V E
Sbjct: 856 -------------KLSREKADKEGIA-----------------KNRLELMPCVVLTRVKE 885
Query: 173 TEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKE 232
E G V +A ++ SS+ ++ K V + S +S E
Sbjct: 886 KE--------GKVIDHTPVEKLKAKLDNDTVKSSA----LDQKLQVSQTEPAKSDLSKLE 933
Query: 233 SPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESE--SSEEGSESEEEAPAGTRSQ 290
S K G V K G L A++ KPE+ ++ S+ + + E S
Sbjct: 934 SVRMKVPKEKGLSSHVEVVEKEGRL-KARKHLKPEQPADGVSAVDLEKLEARKRRFADSN 992
Query: 291 VKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSE 350
+KA ++ +V+ +S P + V S+ +P+ S
Sbjct: 993 LKAEKQKPEVKKSS--------------PEMEDARVLSKK---QPDVSSREVILLREGEA 1035
Query: 351 EETPAAKALLQAKASG-KTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREED 409
E P K +L+ ++ K ++ ++P K+ + G + +A+ G E
Sbjct: 1036 ERKPVRKEILKRESKKIKLDRLNTVASP-KDCQELASISVGSGSRPSSDLQARLG---EL 1091
Query: 410 SQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAA----PAPPRKTG 460
+ S E + + + P +KP K QV P +E RK P RK+G
Sbjct: 1092 AGESVENQEVQSKKPIPSKPQLKQLQVLDDQGPEREDVRKNYCSLRDETPERKSG 1146
Score = 33.9 bits (76), Expect = 1.2
Identities = 34/139 (24%), Positives = 58/139 (41%), Gaps = 29/139 (20%)
Query: 247 DVTPQVKGGALPPAKRAKKPEEESES-SEEGSESEEEAPAGTRSQVKASEKILQVRAASA 305
D+T +V+G +R ++ + S S S S+S ++P SQ AS
Sbjct: 223 DITREVRG------RRPERNYQHSRSRSPHSSQSRNQSPQRLASQ------------ASR 264
Query: 306 PAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKAS 365
P + G G+ +S + + + S SSS++S A+++ A
Sbjct: 265 PTRSPSGSGSRSRSSSSDSISSSSSTSSDSSDSSSSSSDDS--------PARSVQSAAVP 316
Query: 366 GKTSQVGAASAPAKESPRK 384
TSQ+ S+ K+ PRK
Sbjct: 317 APTSQL--LSSLEKDEPRK 333
Score = 32.0 bits (71), Expect = 4.5
Identities = 73/361 (20%), Positives = 118/361 (32%), Gaps = 53/361 (14%)
Query: 69 AALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAE 128
+++ +++ + P S +++ ++ E TP L S S+ L S +
Sbjct: 3069 SSIHPEQSVIMPPHSITQTVSLSHLSQGEVRMNTPTLPSITYSIRPEALHSPRAPLQPQQ 3128
Query: 129 TEKAGKTGNSMPHPATGKTVANLLSGKSPR----------KSAEPSANTTLVSETE---E 175
E S P PA A L S P ++ P + LV ++E
Sbjct: 3129 IEVRAPQRASTPQPAPAGVPA-LASQHPPEEEVHYHLPVARATAPVQSEVLVMQSEYRLH 3187
Query: 176 EGSVPAFGAAAKPGMVSAGQADSSSED----TSSSSDETDVEGKPSVKPAQVKASSVSTK 231
+VP V+A + D +S GK + K KA+ T
Sbjct: 3188 PYTVPRDVRIMVHPHVTAVSEQPRAADGVVKVPPASKAPQQPGKEAAKTPDAKAAPTPTP 3247
Query: 232 ES---PARKAAPAPGKVGD-----VTP--QVKGGALPPAKRAKKPEEESESSEE------ 275
P APAP G+ VTP Q++G L P + SS E
Sbjct: 3248 APVPVPVPLPAPAPAPHGEARILTVTPSNQLQGLPLTPPVVVTHGVQIVHSSGELFQEYR 3307
Query: 276 -GSESEEEAPAG-TRSQVKASEKILQVRAASAPAKGTPGKG-----------------AT 316
G PA T +Q A+ + A+G P +G A
Sbjct: 3308 YGDIRTYHPPAQLTHTQFPAASSVGLPSRTKTAAQGPPPEGEPLQPPQPVQSTQPAQPAP 3367
Query: 317 PAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASA 376
P PP + G + P+ E+ ++ + PA A + + + A +
Sbjct: 3368 PCPPSQLGQPGQPPSSKMPQVSQEAKGTQTGVEQPRLPAGPANRPPEPHTQVQRAQAETG 3427
Query: 377 P 377
P
Sbjct: 3428 P 3428
>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 90.5 bits (223), Expect = 1e-17
Identities = 235/1308 (17%), Positives = 441/1308 (33%), Gaps = 120/1308 (9%)
Query: 107 STNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSAN 166
+T +S G++ + + + ++ T + + P P +T +SG
Sbjct: 15 TTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSE---------- 64
Query: 167 TTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKAS 226
++ T GS ++A G +A A S + +++ S+ T V +
Sbjct: 65 ---ITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMG 121
Query: 227 SVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAG 286
S +T S G T V E + +S GSE AG
Sbjct: 122 SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG 181
Query: 287 ----TRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESS 342
T S + + + T G T A + A+ T + + S +
Sbjct: 182 SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241
Query: 343 SEES-SDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKA 401
SE + S + ET AA + +T+ + + G TG A
Sbjct: 242 SETTVSTAGSETTAA-----STEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296
Query: 402 QAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRK---GAAPAPPRK 458
S SE + + P K S + +V A E+ R G+
Sbjct: 297 --------STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVST 348
Query: 459 TGPAAAQVQVGKQE---------EDSRSSSEESDSDREALAAMNAAQVKPLGK---SPQV 506
TG + E E + +S+E S++ + A V G + +
Sbjct: 349 TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408
Query: 507 KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 566
+ T G V T S + + S S SE ++ S++G T V
Sbjct: 409 TDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468
Query: 567 AQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAA 626
A ++ T++ + + + ++ ++E SE ++ SA E
Sbjct: 469 AGSETKTAYTTGSETTTASNTGLETT--TVFTIGSDTTTASTEGSETTAVSATGSEMTTV 526
Query: 627 MTAAQAKPALKIPQTKACP-----KKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPA 681
T + ++ +T TT++ V T +T +G++ A
Sbjct: 527 STEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 586
Query: 682 VAGGTQRPAEDSSSSEE--SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGT 739
G++ ++ SE + + + +T A T G + + + +GS
Sbjct: 587 STAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGS----- 641
Query: 740 APVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARA 799
T T V E + +S E S++ +A+ ++ S T+ +
Sbjct: 642 ETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS---TEGSGTTTVSIT 698
Query: 800 PSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQ 859
S +S G T + + + +T G + + + T +
Sbjct: 699 GSETTKVSTTGSETTTTS---TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755
Query: 860 AQTGPEEDSG---SSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP 916
+ TG E + SSE S +ET +T ++ A + + + T
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815
Query: 917 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 976
T A++ +GS + + + G TS + + S G T A
Sbjct: 816 STT---ASETTTVSTAGSETIPASTAGSETTTTTSTEGSE------TTTASTEGSETTTA 866
Query: 977 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKAS 1036
+++ T T +S+ SE T T G T + + +
Sbjct: 867 STESSETTTATTIGSETTTASTEGSE------TTTTSTEGSETTTASTE------GSEIT 914
Query: 1037 MAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQ 1096
+ S+ ++ ++G + +T+ S + T+ T ++ +V A+G+ +
Sbjct: 915 TVSTTGSETTTASTEGSETTTASTE-GSELTTVSTTGSETITVSAEGSETTTVTTMG--S 971
Query: 1097 QATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETL------VEETA 1150
+ T A S+ SE ++ S++GSE +G+++ T V T S T T+ T+
Sbjct: 972 ETTTA--STAGSETTTVSTAGSETTTASIEGSET--TTVSSTGSETTTVSTTGTETTITS 1027
Query: 1151 AESSEDDVVAPSQSLLSG-YMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQE 1209
E SE V + S + Y T T S T + ++ S ++T + D +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST---ADLETT 1084
Query: 1210 AKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPL 1269
+G + T G E + S+ +A+T++ S+ T
Sbjct: 1085 TVSTSGSGTTTASTAGSETTT-VYITGSKTTTASTEGSEATTVSTTSSET---------T 1134
Query: 1270 NEAQVQASVVKVLTELLEQERKKVVDT-TKESSRKGWESRKRKLSGDQ-PAARTPRSKKK 1327
+ + + V T + E + + SS G E+ G + A T S+
Sbjct: 1135 TASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETT 1194
Query: 1328 KKLGAG-EGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ 1374
AG E AS + +T+T S ++ + A E S GS+
Sbjct: 1195 TASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE 1242
Score = 90.5 bits (223), Expect = 1e-17
Identities = 210/1165 (18%), Positives = 395/1165 (33%), Gaps = 114/1165 (9%)
Query: 76 TRVSDPISTSESSEEEEEAE---AETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKA 132
T S+ + S + E A +ET K + + T S G++ ++ E ++ T
Sbjct: 209 TTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT 268
Query: 133 GKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVS 192
+ + +T A +G P ++ + TT+ S E + + ++ + +
Sbjct: 269 EDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFA 328
Query: 193 AGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQV 252
AG + S + G + A + S ST + + A + + T
Sbjct: 329 AGSETIRASTVGSETTTVSTTGSETT-TASIMGSETSTDSTTGSETTTASTEGSETTTAS 387
Query: 253 KGGALPPAKRAKKPE------EESESSEEGSESEEEAPAGTR--SQVKASEKILQVRAAS 304
G+ E +SE++ +E E T AS + ++ AS
Sbjct: 388 TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIAS 447
Query: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364
T + S+TK SE+++ ++ E T A
Sbjct: 448 TSDSETTTASTEGSETTTVTTAGSETKTAY-TTGSETTTASNTGLETTTVFTIGSDTTTA 506
Query: 365 SGKTSQVGAASAPAKES---PRKGAAPAPPGKTG------------PAVAKAQAGKREED 409
S + S+ A SA E +G+ TG + +
Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566
Query: 410 SQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVG 469
S + +E + E S + S E+ A + ++
Sbjct: 567 STTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTA 626
Query: 470 K--QEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV---KPASTMGMGPLGKGAGPV 524
E + +S+E S++ + V G + + + T + G
Sbjct: 627 STTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS 686
Query: 525 PPGKVGPATPSAQVGKWEEDSESSSEESSDSSDG-EVPTAVAPAQEKSLGNILQAKPTSS 583
G G T S + + S + SE ++ S++G E+ TA E + + ++ T++
Sbjct: 687 TEGS-GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 584 PAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKA 643
+G + A +E ++ SSE + S E A T + +K
Sbjct: 746 STEGSETTS---ASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 802
Query: 644 CPKKTNTTASAKVAPVRVGTQAPRKAGTATSP---AGSSPAVAGGTQRPAEDSSSSEESD 700
T + + + T AG+ T P AGS T+ ++S+E S+
Sbjct: 803 TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862
Query: 701 -----SEEEKTGLAVTVGQAKSVG--KGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQ 753
+E +T A T+G + +G + S +G+ G +T
Sbjct: 863 TTTASTESSETTTATTIGSETTTASTEGSETTTTST-------EGSETTTASTEGSEITT 915
Query: 754 VKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVV 813
V E + +S E S++ A+ +++ T+V T ++ +A S T++ G
Sbjct: 916 VSTTGSETTTASTEGSETTTASTEGSEL-TTVSTTGSETITVSAEG-SETTTVTTMGSET 973
Query: 814 TAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGS--- 870
T A+ A + +TV G + + + T + TG E + S
Sbjct: 974 TTASTA-------------GSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Query: 871 SEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQD 930
+E S E +ET +T + + + +G+ T TG A D
Sbjct: 1021 TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTAD 1080
Query: 931 DSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARAS 990
++ S S G A+ ++ +++ G T A + + + S
Sbjct: 1081 LETTTVSTSGS-GTTTASTAGSET---TTVYI------TGSKTTTASTEGSEATTVSTTS 1130
Query: 991 ESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRIS 1050
T +S++ SE V V+ T I +A+ + A+ S+ ++ +
Sbjct: 1131 SETTTASTTGSEMTTVF------------TTVSETTTVSTIGSEATTSSAAGSEATTTST 1178
Query: 1051 DGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSED 1110
+G + +T A S +T+ A E A + SE
Sbjct: 1179 EGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTA-----CTTGSET 1233
Query: 1111 SSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYM 1170
S+ SS+GSE + G++ T + T S T T +E++ + A
Sbjct: 1234 STPSSAGSETNTAFIIGSE---TTIASTASLEPTATSLTGSETTTVSITA---------- 1280
Query: 1171 TPGLTPANSQASKATPKLDSSPSVS 1195
G T A++ S T L + VS
Sbjct: 1281 -SGATAASTTVSSTTFVLTKATDVS 1304
Score = 63.2 bits (152), Expect = 2e-09
Identities = 153/774 (19%), Positives = 257/774 (33%), Gaps = 75/774 (9%)
Query: 640 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT-SPAGSSPAVAGGTQRPAEDSSSSEE 698
+T P + T +A T + + T T S AGS T S S
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 758
+ G T + G A S + G T V TG T V A
Sbjct: 64 EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTV--SITGTETTMVSAMG 121
Query: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 818
E + +S + SE S A +T+ T A A S S G +T
Sbjct: 122 SETTTNS--TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFT 179
Query: 819 AKQRSPSKVKPPVRNPQNSTVLARG--PASVPSVGKAVATAAQAQTGPEEDSGSSEEESD 876
A + + P + +TV G +V + G TA+ A SE +
Sbjct: 180 AGSET---ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH---------SETTAA 227
Query: 877 SEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSS 936
S +ET +V +G + A AA T +T + + K + ++
Sbjct: 228 STMGSET-TKVSTAGSETTVSTA------GSETTAASTEDSETNTAFTEDSKTTTASTTG 280
Query: 937 EESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARS 996
E+ + + T A + S GP T ++ A T R+
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMA----STIGPETTKVSTASSEVTTVFAAGSETIRA 336
Query: 997 SSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQE 1056
S+ SE T T G T ++ + ++S E S + +
Sbjct: 337 STVGSE------TTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEG 390
Query: 1057 GPATQVD---SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSD------- 1106
AT V S T+ T ++T+ +G +++ + T + E S+
Sbjct: 391 SEATTVSTTGSETTTVSITDSETTTTCTEG-SEMTAVSTTVFETTTASTEGSEITIASTS 449
Query: 1107 DSEDSSDSSSGSEEDGEGPQGA--KSAHTLVGPTPSRTETLVEET------------AAE 1152
DSE ++ S+ GSE G+ K+A+T T + + T +E T + E
Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTE 509
Query: 1153 SSEDDVVAPSQSLLSGYMTPGL--TPANSQASKATP------KLDSSPSVSSTLAAKDDP 1204
SE V+ + S ++ T G T ++ S+ T + ++ + S +
Sbjct: 510 GSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT 569
Query: 1205 DGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLG 1264
+ + +G + T G E + +T A + S S T
Sbjct: 570 GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTT 629
Query: 1265 QPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKE---SSRKGWESRKRKLSGDQPAART 1321
+ + V T + E V T E +S +G E+ +G + T
Sbjct: 630 SSETTTASTEGSETTTVST--TDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687
Query: 1322 PRS-KKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ 1374
S + E + S + +T+TTS ++ AS E + GS+
Sbjct: 688 EGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741
Score = 45.8 bits (107), Expect = 3e-04
Identities = 57/336 (16%), Positives = 115/336 (34%), Gaps = 11/336 (3%)
Query: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAK 126
E + + T S+ + S E A E ++ T +++T S + S
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTT-VSTTGSETITVSAEGSETTTVT 967
Query: 127 ---AETEKAGKTGNSMPHPATG--KTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPA 181
+ET A G+ +T +T + G + + TT VS T E ++ +
Sbjct: 968 TMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS 1027
Query: 182 FGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPA 241
+ + +AG ++ T S + T EG + + + + + + +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVS 1087
Query: 242 PGKVGDVTPQVKGGALPPA--KRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQ 299
G T G +K +E SE + S + T S + +
Sbjct: 1088 TSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVF 1147
Query: 300 VRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL 359
+ T G AT + + A + T+ + S + SE ++ S T ++
Sbjct: 1148 TTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS---TAGSETT 1204
Query: 360 LQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 395
+ A +T+ + + + G+ + P G
Sbjct: 1205 TASTAGSETTTASTSGSETNTACTTGSETSTPSSAG 1240
>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1612
Score = 90.5 bits (223), Expect = 1e-17
Identities = 209/1175 (17%), Positives = 398/1175 (33%), Gaps = 104/1175 (8%)
Query: 76 TRVSDPISTSESSEEEEEAE---AETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKA 132
T S+ + S + E A +ET K + + T S G++ ++ E ++ T
Sbjct: 209 TTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT 268
Query: 133 GKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVS 192
+ + +T A +G P ++ + TT+ S E + + ++ + +
Sbjct: 269 EDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFA 328
Query: 193 AGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQV 252
AG + S + G + A + S ST + + A + + T
Sbjct: 329 AGSETIRASTVGSETTTVSTTGSETT-TASIMGSETSTDSTTGSETTTASTEGSETTTAS 387
Query: 253 KGGALPPAKRAKKPE------EESESSEEGSESEEEAPAGTR--SQVKASEKILQVRAAS 304
G+ E +SE++ +E E T AS + ++ AS
Sbjct: 388 TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIAS 447
Query: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364
T + S+TK SE+++ ++ E T A
Sbjct: 448 TSDSETTTASTEGSETTTVTTAGSETKTAY-TTGSETTTASNTGLETTTVFTIGSDTTTA 506
Query: 365 SGKTSQVGAASAPAKES---PRKGAAPAPPGKTG------------PAVAKAQAGKREED 409
S + S+ A SA E +G+ TG + +
Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566
Query: 410 SQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVG 469
S + +E + E S + S E+ A + ++
Sbjct: 567 STTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTA 626
Query: 470 K--QEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV---KPASTMGMGPLGKGAGPV 524
E + +S+E S++ + V G + + + T + G
Sbjct: 627 STTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS 686
Query: 525 PPGKVGPATPSAQVGKWEEDSESSSEESSDSSDG-EVPTAVAPAQEKSLGNILQAKPTSS 583
G G T S + + S + SE ++ S++G E+ TA E + + ++ T++
Sbjct: 687 TEGS-GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 584 PAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKA 643
+G + A +E ++ SSE + S E A T + +K
Sbjct: 746 STEGSETTS---ASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 802
Query: 644 CPKKTNTTASAKVAPVRVGTQAPRKAGTATSP---AGSSPAVAGGTQRPAEDSSSSEESD 700
T + + + T AG+ T P AGS T+ ++S+E S+
Sbjct: 803 TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862
Query: 701 -----SEEEKTGLAVTVGQAKSVG--KGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQ 753
+E +T A T+G + +G + S +G+ G +T
Sbjct: 863 TTTASTESSETTTATTIGSETTTASTEGSETTTTST-------EGSETTTASTEGSEITT 915
Query: 754 VKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVV 813
V E + +S E S++ A+ +++ T+V T ++ +A S T++ G
Sbjct: 916 VSTTGSETTTASTEGSETTTASTEGSEL-TTVSTTGSETITVSAEG-SETTTVTTMGSET 973
Query: 814 TAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGS--- 870
T A+ A + +TV G + + + T + TG E + S
Sbjct: 974 TTASTA-------------GSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Query: 871 SEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQD 930
+E S E +ET +T + + + +G+ T TG A D
Sbjct: 1021 TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTAD 1080
Query: 931 DSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARAS 990
++ S S G A+ ++ +++ G T A + + + S
Sbjct: 1081 LETTTVSTSGS-GTTTASTAGSET---TTVYI------TGSKTTTASTEGSEATTVSTTS 1130
Query: 991 ESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRIS 1050
T +S++ SE V V+ T I +A+ + A+ S+ ++ +
Sbjct: 1131 SETTTASTTGSEMTTVF------------TTVSETTTVSTIGSEATTSSAAGSEATTTST 1178
Query: 1051 DGKK-----QEGPATQVDSAVG---TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1102
+G + G T S G T +TS T+ ++ P + T
Sbjct: 1179 EGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFI 1238
Query: 1103 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAP- 1161
S+ + S+ S + G + + T G T + T + D + P
Sbjct: 1239 IGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPI 1298
Query: 1162 SQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSS 1196
+ + +SG T G P S + P +D + S +S
Sbjct: 1299 TNTPMSGTRTTGTRPTASSSVTMAPGMDFTASAAS 1333
Score = 87.4 bits (215), Expect = 9e-17
Identities = 230/1306 (17%), Positives = 436/1306 (33%), Gaps = 126/1306 (9%)
Query: 107 STNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSAN 166
+T +S G++ + + + ++ T + + P P +T +SG
Sbjct: 15 TTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSE---------- 64
Query: 167 TTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKAS 226
++ T GS ++A G +A A S + +++ S+ T V +
Sbjct: 65 ---ITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMG 121
Query: 227 SVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAG 286
S +T S G T V E + +S GSE AG
Sbjct: 122 SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG 181
Query: 287 ----TRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESS 342
T S + + + T G T A + A+ T + + S +
Sbjct: 182 SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241
Query: 343 SEES-SDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKA 401
SE + S + ET AA + +T+ + + G TG A
Sbjct: 242 SETTVSTAGSETTAA-----STEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296
Query: 402 QAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRK---GAAPAPPRK 458
S SE + + P K S + +V A E+ R G+
Sbjct: 297 --------STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVST 348
Query: 459 TGPAAAQVQVGKQE---------EDSRSSSEESDSDREALAAMNAAQVKPLGK---SPQV 506
TG + E E + +S+E S++ + A V G + +
Sbjct: 349 TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408
Query: 507 KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 566
+ T G V T S + + S S SE ++ S++G T V
Sbjct: 409 TDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468
Query: 567 AQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAA 626
A ++ T++ + + + ++ ++E SE ++ SA E
Sbjct: 469 AGSETKTAYTTGSETTTASNTGLETT--TVFTIGSDTTTASTEGSETTAVSATGSEMTTV 526
Query: 627 MTAAQAKPALKIPQTKACP-----KKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPA 681
T + ++ +T TT++ V T +T +G++ A
Sbjct: 527 STEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 586
Query: 682 VAGGTQRPAEDSSSSEE--SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGT 739
G++ ++ SE + + + +T A T G + + + +GS
Sbjct: 587 STAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGS----- 641
Query: 740 APVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARA 799
T T V E + +S E S++ +A+ ++ S T+ +
Sbjct: 642 ETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS---TEGSGTTTVSIT 698
Query: 800 PSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQ 859
S +S G T + + + +T G + + + T +
Sbjct: 699 GSETTKVSTTGSETTTTS---TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755
Query: 860 AQTGPEEDSG---SSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP 916
+ TG E + SSE S +ET +T ++ A + + + T
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815
Query: 917 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 976
T A++ +GS + + + G TS + + S G T A
Sbjct: 816 STT---ASETTTVSTAGSETIPASTAGSETTTTTSTEGSE------TTTASTEGSETTTA 866
Query: 977 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKAS 1036
+++ T T +S+ SE T T G T + + +
Sbjct: 867 STESSETTTATTIGSETTTASTEGSE------TTTTSTEGSETTTASTE------GSEIT 914
Query: 1037 MAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQ 1096
+ S+ ++ ++G + +T+ S + T+ T ++ +V A+G+ +
Sbjct: 915 TVSTTGSETTTASTEGSETTTASTE-GSELTTVSTTGSETITVSAEGSETTTVTTMG--S 971
Query: 1097 QATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETL------VEETA 1150
+ T A S+ SE ++ S++GSE +G+++ T V T S T T+ T+
Sbjct: 972 ETTTA--STAGSETTTVSTAGSETTTASIEGSET--TTVSSTGSETTTVSTTGTETTITS 1027
Query: 1151 AESSEDDVVAPSQSLLSG-YMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQE 1209
E SE V + S + Y T T S T + ++ S ++T + D +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST---ADLETT 1084
Query: 1210 AKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPL 1269
+G + T G E + S+ +A+T++ S+ T
Sbjct: 1085 TVSTSGSGTTTASTAGSETTT-VYITGSKTTTASTEGSEATTVSTTSSET---------T 1134
Query: 1270 NEAQVQASVVKVLTELLEQERKKVVDT-TKESSRKGWESRKRKLSGDQPAARTPRSKKKK 1328
+ + + V T + E + + SS G E+ G + +
Sbjct: 1135 TASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS------- 1187
Query: 1329 KLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ 1374
E AS + +T+T S ++ + A E S GS+
Sbjct: 1188 -TAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE 1232
Score = 63.2 bits (152), Expect = 2e-09
Identities = 153/774 (19%), Positives = 257/774 (33%), Gaps = 75/774 (9%)
Query: 640 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT-SPAGSSPAVAGGTQRPAEDSSSSEE 698
+T P + T +A T + + T T S AGS T S S
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 758
+ G T + G A S + G T V TG T V A
Sbjct: 64 EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTV--SITGTETTMVSAMG 121
Query: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 818
E + +S + SE S A +T+ T A A S S G +T
Sbjct: 122 SETTTNS--TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFT 179
Query: 819 AKQRSPSKVKPPVRNPQNSTVLARG--PASVPSVGKAVATAAQAQTGPEEDSGSSEEESD 876
A + + P + +TV G +V + G TA+ A SE +
Sbjct: 180 AGSET---ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH---------SETTAA 227
Query: 877 SEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSS 936
S +ET +V +G + A AA T +T + + K + ++
Sbjct: 228 STMGSET-TKVSTAGSETTVSTA------GSETTAASTEDSETNTAFTEDSKTTTASTTG 280
Query: 937 EESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARS 996
E+ + + T A + S GP T ++ A T R+
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMA----STIGPETTKVSTASSEVTTVFAAGSETIRA 336
Query: 997 SSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQE 1056
S+ SE T T G T ++ + ++S E S + +
Sbjct: 337 STVGSE------TTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEG 390
Query: 1057 GPATQVD---SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSD------- 1106
AT V S T+ T ++T+ +G +++ + T + E S+
Sbjct: 391 SEATTVSTTGSETTTVSITDSETTTTCTEG-SEMTAVSTTVFETTTASTEGSEITIASTS 449
Query: 1107 DSEDSSDSSSGSEEDGEGPQGA--KSAHTLVGPTPSRTETLVEET------------AAE 1152
DSE ++ S+ GSE G+ K+A+T T + + T +E T + E
Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTE 509
Query: 1153 SSEDDVVAPSQSLLSGYMTPGL--TPANSQASKATP------KLDSSPSVSSTLAAKDDP 1204
SE V+ + S ++ T G T ++ S+ T + ++ + S +
Sbjct: 510 GSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT 569
Query: 1205 DGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLG 1264
+ + +G + T G E + +T A + S S T
Sbjct: 570 GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTT 629
Query: 1265 QPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKE---SSRKGWESRKRKLSGDQPAART 1321
+ + V T + E V T E +S +G E+ +G + T
Sbjct: 630 SSETTTASTEGSETTTVST--TDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687
Query: 1322 PRS-KKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ 1374
S + E + S + +T+TTS ++ AS E + GS+
Sbjct: 688 EGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741
Score = 45.1 bits (105), Expect = 5e-04
Identities = 61/328 (18%), Positives = 113/328 (34%), Gaps = 14/328 (4%)
Query: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAK 126
E + + T S+ + S E A E ++ T +++T S + S
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTT-VSTTGSETITVSAEGSETTTVT 967
Query: 127 ---AETEKAGKTGNSMPHPATG--KTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPA 181
+ET A G+ +T +T + G + + TT VS T E ++ +
Sbjct: 968 TMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS 1027
Query: 182 FGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPA 241
+ + +AG ++ T S + T EG + + + + + + +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVS 1087
Query: 242 PGKVGDVTPQVKGGALPPA--KRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQ 299
G T G +K +E SE + S + T S + +
Sbjct: 1088 TSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVF 1147
Query: 300 VRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL 359
+ T G AT + AG+ A+ T E SE+++ ++ SE T +
Sbjct: 1148 TTVSETTTVSTIGSEATTS--SAAGSEATTTST----EGSETTTASTAGSETTTASTAGS 1201
Query: 360 LQAKASGKTSQVGAASAPAKESPRKGAA 387
AS S+ A E+ +A
Sbjct: 1202 ETTTASTSGSETNTACTTGSETSTPSSA 1229
>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1704
Score = 90.5 bits (223), Expect = 1e-17
Identities = 209/1175 (17%), Positives = 398/1175 (33%), Gaps = 104/1175 (8%)
Query: 76 TRVSDPISTSESSEEEEEAE---AETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKA 132
T S+ + S + E A +ET K + + T S G++ ++ E ++ T
Sbjct: 209 TTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT 268
Query: 133 GKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVS 192
+ + +T A +G P ++ + TT+ S E + + ++ + +
Sbjct: 269 EDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFA 328
Query: 193 AGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQV 252
AG + S + G + A + S ST + + A + + T
Sbjct: 329 AGSETIRASTVGSETTTVSTTGSETT-TASIMGSETSTDSTTGSETTTASTEGSETTTAS 387
Query: 253 KGGALPPAKRAKKPE------EESESSEEGSESEEEAPAGTR--SQVKASEKILQVRAAS 304
G+ E +SE++ +E E T AS + ++ AS
Sbjct: 388 TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIAS 447
Query: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364
T + S+TK SE+++ ++ E T A
Sbjct: 448 TSDSETTTASTEGSETTTVTTAGSETKTAY-TTGSETTTASNTGLETTTVFTIGSDTTTA 506
Query: 365 SGKTSQVGAASAPAKES---PRKGAAPAPPGKTG------------PAVAKAQAGKREED 409
S + S+ A SA E +G+ TG + +
Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566
Query: 410 SQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVG 469
S + +E + E S + S E+ A + ++
Sbjct: 567 STTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTA 626
Query: 470 K--QEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV---KPASTMGMGPLGKGAGPV 524
E + +S+E S++ + V G + + + T + G
Sbjct: 627 STTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS 686
Query: 525 PPGKVGPATPSAQVGKWEEDSESSSEESSDSSDG-EVPTAVAPAQEKSLGNILQAKPTSS 583
G G T S + + S + SE ++ S++G E+ TA E + + ++ T++
Sbjct: 687 TEGS-GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 584 PAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKA 643
+G + A +E ++ SSE + S E A T + +K
Sbjct: 746 STEGSETTS---ASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 802
Query: 644 CPKKTNTTASAKVAPVRVGTQAPRKAGTATSP---AGSSPAVAGGTQRPAEDSSSSEESD 700
T + + + T AG+ T P AGS T+ ++S+E S+
Sbjct: 803 TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862
Query: 701 -----SEEEKTGLAVTVGQAKSVG--KGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQ 753
+E +T A T+G + +G + S +G+ G +T
Sbjct: 863 TTTASTESSETTTATTIGSETTTASTEGSETTTTST-------EGSETTTASTEGSEITT 915
Query: 754 VKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVV 813
V E + +S E S++ A+ +++ T+V T ++ +A S T++ G
Sbjct: 916 VSTTGSETTTASTEGSETTTASTEGSEL-TTVSTTGSETITVSAEG-SETTTVTTMGSET 973
Query: 814 TAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGS--- 870
T A+ A + +TV G + + + T + TG E + S
Sbjct: 974 TTASTA-------------GSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Query: 871 SEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQD 930
+E S E +ET +T + + + +G+ T TG A D
Sbjct: 1021 TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTAD 1080
Query: 931 DSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARAS 990
++ S S G A+ ++ +++ G T A + + + S
Sbjct: 1081 LETTTVSTSGS-GTTTASTAGSET---TTVYI------TGSKTTTASTEGSEATTVSTTS 1130
Query: 991 ESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRIS 1050
T +S++ SE V V+ T I +A+ + A+ S+ ++ +
Sbjct: 1131 SETTTASTTGSEMTTVF------------TTVSETTTVSTIGSEATTSSAAGSEATTTST 1178
Query: 1051 DGKK-----QEGPATQVDSAVG---TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAP 1102
+G + G T S G T +TS T+ ++ P + T
Sbjct: 1179 EGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFI 1238
Query: 1103 ESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAP- 1161
S+ + S+ S + G + + T G T + T + D + P
Sbjct: 1239 IGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPI 1298
Query: 1162 SQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSS 1196
+ + +SG T G P S + P +D + S +S
Sbjct: 1299 TNTPMSGTRTTGTRPTASSSVTMAPGMDFTASAAS 1333
Score = 87.4 bits (215), Expect = 9e-17
Identities = 230/1306 (17%), Positives = 436/1306 (33%), Gaps = 126/1306 (9%)
Query: 107 STNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSAN 166
+T +S G++ + + + ++ T + + P P +T +SG
Sbjct: 15 TTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSE---------- 64
Query: 167 TTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKAS 226
++ T GS ++A G +A A S + +++ S+ T V +
Sbjct: 65 ---ITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMG 121
Query: 227 SVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAG 286
S +T S G T V E + +S GSE AG
Sbjct: 122 SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG 181
Query: 287 ----TRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESS 342
T S + + + T G T A + A+ T + + S +
Sbjct: 182 SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241
Query: 343 SEES-SDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKA 401
SE + S + ET AA + +T+ + + G TG A
Sbjct: 242 SETTVSTAGSETTAA-----STEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296
Query: 402 QAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRK---GAAPAPPRK 458
S SE + + P K S + +V A E+ R G+
Sbjct: 297 --------STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVST 348
Query: 459 TGPAAAQVQVGKQE---------EDSRSSSEESDSDREALAAMNAAQVKPLGK---SPQV 506
TG + E E + +S+E S++ + A V G + +
Sbjct: 349 TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408
Query: 507 KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 566
+ T G V T S + + S S SE ++ S++G T V
Sbjct: 409 TDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468
Query: 567 AQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAA 626
A ++ T++ + + + ++ ++E SE ++ SA E
Sbjct: 469 AGSETKTAYTTGSETTTASNTGLETT--TVFTIGSDTTTASTEGSETTAVSATGSEMTTV 526
Query: 627 MTAAQAKPALKIPQTKACP-----KKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPA 681
T + ++ +T TT++ V T +T +G++ A
Sbjct: 527 STEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 586
Query: 682 VAGGTQRPAEDSSSSEE--SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGT 739
G++ ++ SE + + + +T A T G + + + +GS
Sbjct: 587 STAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGS----- 641
Query: 740 APVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARA 799
T T V E + +S E S++ +A+ ++ S T+ +
Sbjct: 642 ETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS---TEGSGTTTVSIT 698
Query: 800 PSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQ 859
S +S G T + + + +T G + + + T +
Sbjct: 699 GSETTKVSTTGSETTTTS---TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755
Query: 860 AQTGPEEDSG---SSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP 916
+ TG E + SSE S +ET +T ++ A + + + T
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815
Query: 917 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 976
T A++ +GS + + + G TS + + S G T A
Sbjct: 816 STT---ASETTTVSTAGSETIPASTAGSETTTTTSTEGSE------TTTASTEGSETTTA 866
Query: 977 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKAS 1036
+++ T T +S+ SE T T G T + + +
Sbjct: 867 STESSETTTATTIGSETTTASTEGSE------TTTTSTEGSETTTASTE------GSEIT 914
Query: 1037 MAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQ 1096
+ S+ ++ ++G + +T+ S + T+ T ++ +V A+G+ +
Sbjct: 915 TVSTTGSETTTASTEGSETTTASTE-GSELTTVSTTGSETITVSAEGSETTTVTTMG--S 971
Query: 1097 QATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETL------VEETA 1150
+ T A S+ SE ++ S++GSE +G+++ T V T S T T+ T+
Sbjct: 972 ETTTA--STAGSETTTVSTAGSETTTASIEGSET--TTVSSTGSETTTVSTTGTETTITS 1027
Query: 1151 AESSEDDVVAPSQSLLSG-YMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQE 1209
E SE V + S + Y T T S T + ++ S ++T + D +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST---ADLETT 1084
Query: 1210 AKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPL 1269
+G + T G E + S+ +A+T++ S+ T
Sbjct: 1085 TVSTSGSGTTTASTAGSETTT-VYITGSKTTTASTEGSEATTVSTTSSET---------T 1134
Query: 1270 NEAQVQASVVKVLTELLEQERKKVVDT-TKESSRKGWESRKRKLSGDQPAARTPRSKKKK 1328
+ + + V T + E + + SS G E+ G + +
Sbjct: 1135 TASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS------- 1187
Query: 1329 KLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ 1374
E AS + +T+T S ++ + A E S GS+
Sbjct: 1188 -TAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE 1232
Score = 63.2 bits (152), Expect = 2e-09
Identities = 153/774 (19%), Positives = 257/774 (33%), Gaps = 75/774 (9%)
Query: 640 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT-SPAGSSPAVAGGTQRPAEDSSSSEE 698
+T P + T +A T + + T T S AGS T S S
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 758
+ G T + G A S + G T V TG T V A
Sbjct: 64 EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTV--SITGTETTMVSAMG 121
Query: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 818
E + +S + SE S A +T+ T A A S S G +T
Sbjct: 122 SETTTNS--TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFT 179
Query: 819 AKQRSPSKVKPPVRNPQNSTVLARG--PASVPSVGKAVATAAQAQTGPEEDSGSSEEESD 876
A + + P + +TV G +V + G TA+ A SE +
Sbjct: 180 AGSET---ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH---------SETTAA 227
Query: 877 SEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSS 936
S +ET +V +G + A AA T +T + + K + ++
Sbjct: 228 STMGSET-TKVSTAGSETTVSTA------GSETTAASTEDSETNTAFTEDSKTTTASTTG 280
Query: 937 EESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARS 996
E+ + + T A + S GP T ++ A T R+
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMA----STIGPETTKVSTASSEVTTVFAAGSETIRA 336
Query: 997 SSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQE 1056
S+ SE T T G T ++ + ++S E S + +
Sbjct: 337 STVGSE------TTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEG 390
Query: 1057 GPATQVD---SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSD------- 1106
AT V S T+ T ++T+ +G +++ + T + E S+
Sbjct: 391 SEATTVSTTGSETTTVSITDSETTTTCTEG-SEMTAVSTTVFETTTASTEGSEITIASTS 449
Query: 1107 DSEDSSDSSSGSEEDGEGPQGA--KSAHTLVGPTPSRTETLVEET------------AAE 1152
DSE ++ S+ GSE G+ K+A+T T + + T +E T + E
Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTE 509
Query: 1153 SSEDDVVAPSQSLLSGYMTPGL--TPANSQASKATP------KLDSSPSVSSTLAAKDDP 1204
SE V+ + S ++ T G T ++ S+ T + ++ + S +
Sbjct: 510 GSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT 569
Query: 1205 DGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLG 1264
+ + +G + T G E + +T A + S S T
Sbjct: 570 GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTT 629
Query: 1265 QPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKE---SSRKGWESRKRKLSGDQPAART 1321
+ + V T + E V T E +S +G E+ +G + T
Sbjct: 630 SSETTTASTEGSETTTVST--TDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687
Query: 1322 PRS-KKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ 1374
S + E + S + +T+TTS ++ AS E + GS+
Sbjct: 688 EGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741
Score = 45.1 bits (105), Expect = 5e-04
Identities = 61/328 (18%), Positives = 113/328 (34%), Gaps = 14/328 (4%)
Query: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAK 126
E + + T S+ + S E A E ++ T +++T S + S
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTT-VSTTGSETITVSAEGSETTTVT 967
Query: 127 ---AETEKAGKTGNSMPHPATG--KTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPA 181
+ET A G+ +T +T + G + + TT VS T E ++ +
Sbjct: 968 TMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS 1027
Query: 182 FGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPA 241
+ + +AG ++ T S + T EG + + + + + + +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVS 1087
Query: 242 PGKVGDVTPQVKGGALPPA--KRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQ 299
G T G +K +E SE + S + T S + +
Sbjct: 1088 TSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVF 1147
Query: 300 VRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL 359
+ T G AT + AG+ A+ T E SE+++ ++ SE T +
Sbjct: 1148 TTVSETTTVSTIGSEATTS--SAAGSEATTTST----EGSETTTASTAGSETTTASTAGS 1201
Query: 360 LQAKASGKTSQVGAASAPAKESPRKGAA 387
AS S+ A E+ +A
Sbjct: 1202 ETTTASTSGSETNTACTTGSETSTPSSA 1229
>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 90.5 bits (223), Expect = 1e-17
Identities = 235/1308 (17%), Positives = 441/1308 (33%), Gaps = 120/1308 (9%)
Query: 107 STNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSAN 166
+T +S G++ + + + ++ T + + P P +T +SG
Sbjct: 15 TTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSE---------- 64
Query: 167 TTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKAS 226
++ T GS ++A G +A A S + +++ S+ T V +
Sbjct: 65 ---ITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMG 121
Query: 227 SVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAG 286
S +T S G T V E + +S GSE AG
Sbjct: 122 SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG 181
Query: 287 ----TRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESS 342
T S + + + T G T A + A+ T + + S +
Sbjct: 182 SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241
Query: 343 SEES-SDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKA 401
SE + S + ET AA + +T+ + + G TG A
Sbjct: 242 SETTVSTAGSETTAA-----STEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMA 296
Query: 402 QAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRK---GAAPAPPRK 458
S SE + + P K S + +V A E+ R G+
Sbjct: 297 --------STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVST 348
Query: 459 TGPAAAQVQVGKQE---------EDSRSSSEESDSDREALAAMNAAQVKPLGK---SPQV 506
TG + E E + +S+E S++ + A V G + +
Sbjct: 349 TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408
Query: 507 KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 566
+ T G V T S + + S S SE ++ S++G T V
Sbjct: 409 TDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468
Query: 567 AQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAA 626
A ++ T++ + + + ++ ++E SE ++ SA E
Sbjct: 469 AGSETKTAYTTGSETTTASNTGLETT--TVFTIGSDTTTASTEGSETTAVSATGSEMTTV 526
Query: 627 MTAAQAKPALKIPQTKACP-----KKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPA 681
T + ++ +T TT++ V T +T +G++ A
Sbjct: 527 STEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 586
Query: 682 VAGGTQRPAEDSSSSEE--SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGT 739
G++ ++ SE + + + +T A T G + + + +GS
Sbjct: 587 STAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGS----- 641
Query: 740 APVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARA 799
T T V E + +S E S++ +A+ ++ S T+ +
Sbjct: 642 ETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS---TEGSGTTTVSIT 698
Query: 800 PSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQ 859
S +S G T + + + +T G + + + T +
Sbjct: 699 GSETTKVSTTGSETTTTS---TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755
Query: 860 AQTGPEEDSG---SSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPP 916
+ TG E + SSE S +ET +T ++ A + + + T
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815
Query: 917 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 976
T A++ +GS + + + G TS + + S G T A
Sbjct: 816 STT---ASETTTVSTAGSETIPASTAGSETTTTTSTEGSE------TTTASTEGSETTTA 866
Query: 977 QAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKAS 1036
+++ T T +S+ SE T T G T + + +
Sbjct: 867 STESSETTTATTIGSETTTASTEGSE------TTTTSTEGSETTTASTE------GSEIT 914
Query: 1037 MAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQ 1096
+ S+ ++ ++G + +T+ S + T+ T ++ +V A+G+ +
Sbjct: 915 TVSTTGSETTTASTEGSETTTASTE-GSELTTVSTTGSETITVSAEGSETTTVTTMG--S 971
Query: 1097 QATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETL------VEETA 1150
+ T A S+ SE ++ S++GSE +G+++ T V T S T T+ T+
Sbjct: 972 ETTTA--STAGSETTTVSTAGSETTTASIEGSET--TTVSSTGSETTTVSTTGTETTITS 1027
Query: 1151 AESSEDDVVAPSQSLLSG-YMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQE 1209
E SE V + S + Y T T S T + ++ S ++T + D +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST---ADLETT 1084
Query: 1210 AKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPL 1269
+G + T G E + S+ +A+T++ S+ T
Sbjct: 1085 TVSTSGSGTTTASTAGSETTT-VYITGSKTTTASTEGSEATTVSTTSSET---------T 1134
Query: 1270 NEAQVQASVVKVLTELLEQERKKVVDT-TKESSRKGWESRKRKLSGDQ-PAARTPRSKKK 1327
+ + + V T + E + + SS G E+ G + A T S+
Sbjct: 1135 TASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETT 1194
Query: 1328 KKLGAG-EGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ 1374
AG E AS + +T+T S ++ + A E S GS+
Sbjct: 1195 TASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE 1242
Score = 90.5 bits (223), Expect = 1e-17
Identities = 210/1165 (18%), Positives = 395/1165 (33%), Gaps = 114/1165 (9%)
Query: 76 TRVSDPISTSESSEEEEEAE---AETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKA 132
T S+ + S + E A +ET K + + T S G++ ++ E ++ T
Sbjct: 209 TTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT 268
Query: 133 GKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVS 192
+ + +T A +G P ++ + TT+ S E + + ++ + +
Sbjct: 269 EDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFA 328
Query: 193 AGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQV 252
AG + S + G + A + S ST + + A + + T
Sbjct: 329 AGSETIRASTVGSETTTVSTTGSETT-TASIMGSETSTDSTTGSETTTASTEGSETTTAS 387
Query: 253 KGGALPPAKRAKKPE------EESESSEEGSESEEEAPAGTR--SQVKASEKILQVRAAS 304
G+ E +SE++ +E E T AS + ++ AS
Sbjct: 388 TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIAS 447
Query: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364
T + S+TK SE+++ ++ E T A
Sbjct: 448 TSDSETTTASTEGSETTTVTTAGSETKTAY-TTGSETTTASNTGLETTTVFTIGSDTTTA 506
Query: 365 SGKTSQVGAASAPAKES---PRKGAAPAPPGKTG------------PAVAKAQAGKREED 409
S + S+ A SA E +G+ TG + +
Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566
Query: 410 SQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVG 469
S + +E + E S + S E+ A + ++
Sbjct: 567 STTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTA 626
Query: 470 K--QEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV---KPASTMGMGPLGKGAGPV 524
E + +S+E S++ + V G + + + T + G
Sbjct: 627 STTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS 686
Query: 525 PPGKVGPATPSAQVGKWEEDSESSSEESSDSSDG-EVPTAVAPAQEKSLGNILQAKPTSS 583
G G T S + + S + SE ++ S++G E+ TA E + + ++ T++
Sbjct: 687 TEGS-GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 584 PAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKA 643
+G + A +E ++ SSE + S E A T + +K
Sbjct: 746 STEGSETTS---ASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 802
Query: 644 CPKKTNTTASAKVAPVRVGTQAPRKAGTATSP---AGSSPAVAGGTQRPAEDSSSSEESD 700
T + + + T AG+ T P AGS T+ ++S+E S+
Sbjct: 803 TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862
Query: 701 -----SEEEKTGLAVTVGQAKSVG--KGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQ 753
+E +T A T+G + +G + S +G+ G +T
Sbjct: 863 TTTASTESSETTTATTIGSETTTASTEGSETTTTST-------EGSETTTASTEGSEITT 915
Query: 754 VKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVV 813
V E + +S E S++ A+ +++ T+V T ++ +A S T++ G
Sbjct: 916 VSTTGSETTTASTEGSETTTASTEGSEL-TTVSTTGSETITVSAEG-SETTTVTTMGSET 973
Query: 814 TAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGS--- 870
T A+ A + +TV G + + + T + TG E + S
Sbjct: 974 TTASTA-------------GSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Query: 871 SEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQD 930
+E S E +ET +T + + + +G+ T TG A D
Sbjct: 1021 TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTAD 1080
Query: 931 DSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARAS 990
++ S S G A+ ++ +++ G T A + + + S
Sbjct: 1081 LETTTVSTSGS-GTTTASTAGSET---TTVYI------TGSKTTTASTEGSEATTVSTTS 1130
Query: 991 ESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRIS 1050
T +S++ SE V V+ T I +A+ + A+ S+ ++ +
Sbjct: 1131 SETTTASTTGSEMTTVF------------TTVSETTTVSTIGSEATTSSAAGSEATTTST 1178
Query: 1051 DGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSED 1110
+G + +T A S +T+ A E A + SE
Sbjct: 1179 EGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTA-----CTTGSET 1233
Query: 1111 SSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYM 1170
S+ SS+GSE + G++ T + T S T T +E++ + A
Sbjct: 1234 STPSSAGSETNTAFIIGSE---TTIASTASLEPTATSLTGSETTTVSITA---------- 1280
Query: 1171 TPGLTPANSQASKATPKLDSSPSVS 1195
G T A++ S T L + VS
Sbjct: 1281 -SGATAASTTVSSTTFVLTKATDVS 1304
Score = 63.2 bits (152), Expect = 2e-09
Identities = 153/774 (19%), Positives = 257/774 (33%), Gaps = 75/774 (9%)
Query: 640 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT-SPAGSSPAVAGGTQRPAEDSSSSEE 698
+T P + T +A T + + T T S AGS T S S
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 699 SDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEK 758
+ G T + G A S + G T V TG T V A
Sbjct: 64 EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTV--SITGTETTMVSAMG 121
Query: 759 QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQ 818
E + +S + SE S A +T+ T A A S S G +T
Sbjct: 122 SETTTNS--TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFT 179
Query: 819 AKQRSPSKVKPPVRNPQNSTVLARG--PASVPSVGKAVATAAQAQTGPEEDSGSSEEESD 876
A + + P + +TV G +V + G TA+ A SE +
Sbjct: 180 AGSET---ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH---------SETTAA 227
Query: 877 SEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSS 936
S +ET +V +G + A AA T +T + + K + ++
Sbjct: 228 STMGSET-TKVSTAGSETTVSTA------GSETTAASTEDSETNTAFTEDSKTTTASTTG 280
Query: 937 EESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARS 996
E+ + + T A + S GP T ++ A T R+
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMA----STIGPETTKVSTASSEVTTVFAAGSETIRA 336
Query: 997 SSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQE 1056
S+ SE T T G T ++ + ++S E S + +
Sbjct: 337 STVGSE------TTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEG 390
Query: 1057 GPATQVD---SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSD------- 1106
AT V S T+ T ++T+ +G +++ + T + E S+
Sbjct: 391 SEATTVSTTGSETTTVSITDSETTTTCTEG-SEMTAVSTTVFETTTASTEGSEITIASTS 449
Query: 1107 DSEDSSDSSSGSEEDGEGPQGA--KSAHTLVGPTPSRTETLVEET------------AAE 1152
DSE ++ S+ GSE G+ K+A+T T + + T +E T + E
Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTE 509
Query: 1153 SSEDDVVAPSQSLLSGYMTPGL--TPANSQASKATP------KLDSSPSVSSTLAAKDDP 1204
SE V+ + S ++ T G T ++ S+ T + ++ + S +
Sbjct: 510 GSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT 569
Query: 1205 DGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLG 1264
+ + +G + T G E + +T A + S S T
Sbjct: 570 GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTT 629
Query: 1265 QPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKE---SSRKGWESRKRKLSGDQPAART 1321
+ + V T + E V T E +S +G E+ +G + T
Sbjct: 630 SSETTTASTEGSETTTVST--TDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687
Query: 1322 PRS-KKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQ 1374
S + E + S + +T+TTS ++ AS E + GS+
Sbjct: 688 EGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741
Score = 45.8 bits (107), Expect = 3e-04
Identities = 57/336 (16%), Positives = 115/336 (34%), Gaps = 11/336 (3%)
Query: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAK 126
E + + T S+ + S E A E ++ T +++T S + S
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTT-VSTTGSETITVSAEGSETTTVT 967
Query: 127 ---AETEKAGKTGNSMPHPATG--KTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPA 181
+ET A G+ +T +T + G + + TT VS T E ++ +
Sbjct: 968 TMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS 1027
Query: 182 FGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPA 241
+ + +AG ++ T S + T EG + + + + + + +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVS 1087
Query: 242 PGKVGDVTPQVKGGALPPA--KRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQ 299
G T G +K +E SE + S + T S + +
Sbjct: 1088 TSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVF 1147
Query: 300 VRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL 359
+ T G AT + + A + T+ + S + SE ++ S T ++
Sbjct: 1148 TTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS---TAGSETT 1204
Query: 360 LQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 395
+ A +T+ + + + G+ + P G
Sbjct: 1205 TASTAGSETTTASTSGSETNTACTTGSETSTPSSAG 1240
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.296 0.114 0.298
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,462,442
Number of Sequences: 37866
Number of extensions: 3631228
Number of successful extensions: 66397
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 751
Number of HSP's successfully gapped in prelim test: 2693
Number of HSP's that attempted gapping in prelim test: 21932
Number of HSP's gapped (non-prelim): 25615
length of query: 1451
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1336
effective length of database: 13,892,928
effective search space: 18560951808
effective search space used: 18560951808
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 44 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.