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Search of human proteins with 206597465
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|206597465 neural precursor cell expressed, developmentally
down-regulated 1 isoform a [Homo sapiens]
(667 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|206597465 neural precursor cell expressed, developmentally do... 1323 0.0
gi|206597468 neural precursor cell expressed, developmentally do... 1308 0.0
gi|23097254 neural precursor cell expressed, developmentally dow... 1308 0.0
gi|206597470 neural precursor cell expressed, developmentally do... 1128 0.0
gi|16554629 WD repeat domain 5 [Homo sapiens] 80 5e-15
gi|16554627 WD repeat domain 5 [Homo sapiens] 80 5e-15
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 73 7e-13
gi|23199987 WD repeat domain 5B [Homo sapiens] 69 2e-11
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 67 4e-11
gi|48762926 PWP2 periodic tryptophan protein homolog [Homo sapiens] 66 1e-10
gi|189571685 WD repeat, sterile alpha motif and U-box domain con... 65 2e-10
gi|189571683 WD repeat, sterile alpha motif and U-box domain con... 65 2e-10
gi|189571681 WD repeat, sterile alpha motif and U-box domain con... 65 2e-10
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 64 4e-10
gi|11321585 guanine nucleotide-binding protein, beta-1 subunit [... 64 6e-10
gi|113865883 WD repeat domain 38 [Homo sapiens] 62 2e-09
gi|55741849 WD repeat domain 22 [Homo sapiens] 61 3e-09
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 61 3e-09
gi|4504053 guanine nucleotide-binding protein, beta-3 subunit [H... 57 7e-08
gi|20357529 guanine nucleotide-binding protein, beta-2 subunit [... 56 1e-07
gi|102470001 PQQ repeat and WD repeat domain containing [Homo sa... 54 4e-07
gi|48928050 F-box and WD repeat domain containing 11 isoform C [... 54 5e-07
gi|48928048 F-box and WD repeat domain containing 11 isoform A [... 54 5e-07
gi|48928046 F-box and WD repeat domain containing 11 isoform B [... 54 5e-07
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 54 6e-07
gi|5174447 guanine nucleotide binding protein (G protein), beta ... 53 8e-07
gi|32189425 WD repeat domain 69 [Homo sapiens] 52 1e-06
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 52 2e-06
gi|13376840 WD repeat domain 61 [Homo sapiens] 52 2e-06
gi|4502477 beta-transducin repeat containing protein isoform 2 [... 51 3e-06
>gi|206597465 neural precursor cell expressed, developmentally
down-regulated 1 isoform a [Homo sapiens]
Length = 667
Score = 1323 bits (3424), Expect = 0.0
Identities = 667/667 (100%), Positives = 667/667 (100%)
Query: 1 MHFTGAVMQENLRFASSGDDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTAS 60
MHFTGAVMQENLRFASSGDDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTAS
Sbjct: 1 MHFTGAVMQENLRFASSGDDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTAS 60
Query: 61 SSGDKIVVSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHR 120
SSGDKIVVSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHR
Sbjct: 61 SSGDKIVVSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHR 120
Query: 121 SLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLF 180
SLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLF
Sbjct: 121 SLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLF 180
Query: 181 KKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIIL 240
KKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIIL
Sbjct: 181 KKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIIL 240
Query: 241 YDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTS 300
YDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTS
Sbjct: 241 YDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTS 300
Query: 301 VQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVNAASGGVQNSGIVREAPATSIATVL 360
VQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVNAASGGVQNSGIVREAPATSIATVL
Sbjct: 301 VQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVNAASGGVQNSGIVREAPATSIATVL 360
Query: 361 PQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDSGKNQDFSSFDDTGKSSLGDMFSPI 420
PQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDSGKNQDFSSFDDTGKSSLGDMFSPI
Sbjct: 361 PQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDSGKNQDFSSFDDTGKSSLGDMFSPI 420
Query: 421 RDDAVVNKGSDESIGKGDGFDFLPQLNSVFPPRKNPVTSSTSVLHSSPLNVFMGSPGKEE 480
RDDAVVNKGSDESIGKGDGFDFLPQLNSVFPPRKNPVTSSTSVLHSSPLNVFMGSPGKEE
Sbjct: 421 RDDAVVNKGSDESIGKGDGFDFLPQLNSVFPPRKNPVTSSTSVLHSSPLNVFMGSPGKEE 480
Query: 481 NENRDLTAESKKIYMGKQESKDSFKQLAKLVTSGAESGNLNTSPSSNQTRNSEKFEKPEN 540
NENRDLTAESKKIYMGKQESKDSFKQLAKLVTSGAESGNLNTSPSSNQTRNSEKFEKPEN
Sbjct: 481 NENRDLTAESKKIYMGKQESKDSFKQLAKLVTSGAESGNLNTSPSSNQTRNSEKFEKPEN 540
Query: 541 EIEAQLICEPPINGSSTPNPKIASSVTAGVASSLSEKIADSIGNNRQNAPLTSIQIRFIQ 600
EIEAQLICEPPINGSSTPNPKIASSVTAGVASSLSEKIADSIGNNRQNAPLTSIQIRFIQ
Sbjct: 541 EIEAQLICEPPINGSSTPNPKIASSVTAGVASSLSEKIADSIGNNRQNAPLTSIQIRFIQ 600
Query: 601 NMIQETLDDFREACHRDIVNLQVEMIKQFHMQLNEMHSLLERYSVNEGLVAEIERLREEN 660
NMIQETLDDFREACHRDIVNLQVEMIKQFHMQLNEMHSLLERYSVNEGLVAEIERLREEN
Sbjct: 601 NMIQETLDDFREACHRDIVNLQVEMIKQFHMQLNEMHSLLERYSVNEGLVAEIERLREEN 660
Query: 661 KRLRAHF 667
KRLRAHF
Sbjct: 661 KRLRAHF 667
>gi|206597468 neural precursor cell expressed, developmentally
down-regulated 1 isoform b [Homo sapiens]
Length = 660
Score = 1308 bits (3386), Expect = 0.0
Identities = 660/660 (100%), Positives = 660/660 (100%)
Query: 8 MQENLRFASSGDDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIV 67
MQENLRFASSGDDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIV
Sbjct: 1 MQENLRFASSGDDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIV 60
Query: 68 VSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKD 127
VSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKD
Sbjct: 61 VSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKD 120
Query: 128 QVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGS 187
QVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGS
Sbjct: 121 QVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGS 180
Query: 188 VSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKK 247
VSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKK
Sbjct: 181 VSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKK 240
Query: 248 LVKTLVADTPLTAVDFMPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQ 307
LVKTLVADTPLTAVDFMPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQ
Sbjct: 241 LVKTLVADTPLTAVDFMPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQ 300
Query: 308 YSTVLTKSSLNKGCSNKPTTVNKRSVNVNAASGGVQNSGIVREAPATSIATVLPQPMTSA 367
YSTVLTKSSLNKGCSNKPTTVNKRSVNVNAASGGVQNSGIVREAPATSIATVLPQPMTSA
Sbjct: 301 YSTVLTKSSLNKGCSNKPTTVNKRSVNVNAASGGVQNSGIVREAPATSIATVLPQPMTSA 360
Query: 368 MGKGTVAVQEKAGLPRSINTDTLSKETDSGKNQDFSSFDDTGKSSLGDMFSPIRDDAVVN 427
MGKGTVAVQEKAGLPRSINTDTLSKETDSGKNQDFSSFDDTGKSSLGDMFSPIRDDAVVN
Sbjct: 361 MGKGTVAVQEKAGLPRSINTDTLSKETDSGKNQDFSSFDDTGKSSLGDMFSPIRDDAVVN 420
Query: 428 KGSDESIGKGDGFDFLPQLNSVFPPRKNPVTSSTSVLHSSPLNVFMGSPGKEENENRDLT 487
KGSDESIGKGDGFDFLPQLNSVFPPRKNPVTSSTSVLHSSPLNVFMGSPGKEENENRDLT
Sbjct: 421 KGSDESIGKGDGFDFLPQLNSVFPPRKNPVTSSTSVLHSSPLNVFMGSPGKEENENRDLT 480
Query: 488 AESKKIYMGKQESKDSFKQLAKLVTSGAESGNLNTSPSSNQTRNSEKFEKPENEIEAQLI 547
AESKKIYMGKQESKDSFKQLAKLVTSGAESGNLNTSPSSNQTRNSEKFEKPENEIEAQLI
Sbjct: 481 AESKKIYMGKQESKDSFKQLAKLVTSGAESGNLNTSPSSNQTRNSEKFEKPENEIEAQLI 540
Query: 548 CEPPINGSSTPNPKIASSVTAGVASSLSEKIADSIGNNRQNAPLTSIQIRFIQNMIQETL 607
CEPPINGSSTPNPKIASSVTAGVASSLSEKIADSIGNNRQNAPLTSIQIRFIQNMIQETL
Sbjct: 541 CEPPINGSSTPNPKIASSVTAGVASSLSEKIADSIGNNRQNAPLTSIQIRFIQNMIQETL 600
Query: 608 DDFREACHRDIVNLQVEMIKQFHMQLNEMHSLLERYSVNEGLVAEIERLREENKRLRAHF 667
DDFREACHRDIVNLQVEMIKQFHMQLNEMHSLLERYSVNEGLVAEIERLREENKRLRAHF
Sbjct: 601 DDFREACHRDIVNLQVEMIKQFHMQLNEMHSLLERYSVNEGLVAEIERLREENKRLRAHF 660
>gi|23097254 neural precursor cell expressed, developmentally
down-regulated 1 isoform b [Homo sapiens]
Length = 660
Score = 1308 bits (3386), Expect = 0.0
Identities = 660/660 (100%), Positives = 660/660 (100%)
Query: 8 MQENLRFASSGDDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIV 67
MQENLRFASSGDDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIV
Sbjct: 1 MQENLRFASSGDDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIV 60
Query: 68 VSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKD 127
VSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKD
Sbjct: 61 VSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKD 120
Query: 128 QVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGS 187
QVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGS
Sbjct: 121 QVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGS 180
Query: 188 VSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKK 247
VSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKK
Sbjct: 181 VSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKK 240
Query: 248 LVKTLVADTPLTAVDFMPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQ 307
LVKTLVADTPLTAVDFMPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQ
Sbjct: 241 LVKTLVADTPLTAVDFMPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQ 300
Query: 308 YSTVLTKSSLNKGCSNKPTTVNKRSVNVNAASGGVQNSGIVREAPATSIATVLPQPMTSA 367
YSTVLTKSSLNKGCSNKPTTVNKRSVNVNAASGGVQNSGIVREAPATSIATVLPQPMTSA
Sbjct: 301 YSTVLTKSSLNKGCSNKPTTVNKRSVNVNAASGGVQNSGIVREAPATSIATVLPQPMTSA 360
Query: 368 MGKGTVAVQEKAGLPRSINTDTLSKETDSGKNQDFSSFDDTGKSSLGDMFSPIRDDAVVN 427
MGKGTVAVQEKAGLPRSINTDTLSKETDSGKNQDFSSFDDTGKSSLGDMFSPIRDDAVVN
Sbjct: 361 MGKGTVAVQEKAGLPRSINTDTLSKETDSGKNQDFSSFDDTGKSSLGDMFSPIRDDAVVN 420
Query: 428 KGSDESIGKGDGFDFLPQLNSVFPPRKNPVTSSTSVLHSSPLNVFMGSPGKEENENRDLT 487
KGSDESIGKGDGFDFLPQLNSVFPPRKNPVTSSTSVLHSSPLNVFMGSPGKEENENRDLT
Sbjct: 421 KGSDESIGKGDGFDFLPQLNSVFPPRKNPVTSSTSVLHSSPLNVFMGSPGKEENENRDLT 480
Query: 488 AESKKIYMGKQESKDSFKQLAKLVTSGAESGNLNTSPSSNQTRNSEKFEKPENEIEAQLI 547
AESKKIYMGKQESKDSFKQLAKLVTSGAESGNLNTSPSSNQTRNSEKFEKPENEIEAQLI
Sbjct: 481 AESKKIYMGKQESKDSFKQLAKLVTSGAESGNLNTSPSSNQTRNSEKFEKPENEIEAQLI 540
Query: 548 CEPPINGSSTPNPKIASSVTAGVASSLSEKIADSIGNNRQNAPLTSIQIRFIQNMIQETL 607
CEPPINGSSTPNPKIASSVTAGVASSLSEKIADSIGNNRQNAPLTSIQIRFIQNMIQETL
Sbjct: 541 CEPPINGSSTPNPKIASSVTAGVASSLSEKIADSIGNNRQNAPLTSIQIRFIQNMIQETL 600
Query: 608 DDFREACHRDIVNLQVEMIKQFHMQLNEMHSLLERYSVNEGLVAEIERLREENKRLRAHF 667
DDFREACHRDIVNLQVEMIKQFHMQLNEMHSLLERYSVNEGLVAEIERLREENKRLRAHF
Sbjct: 601 DDFREACHRDIVNLQVEMIKQFHMQLNEMHSLLERYSVNEGLVAEIERLREENKRLRAHF 660
>gi|206597470 neural precursor cell expressed, developmentally
down-regulated 1 isoform c [Homo sapiens]
Length = 571
Score = 1128 bits (2918), Expect = 0.0
Identities = 571/571 (100%), Positives = 571/571 (100%)
Query: 97 MYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVT 156
MYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVT
Sbjct: 1 MYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVT 60
Query: 157 TNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 216
TNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA
Sbjct: 61 TNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 120
Query: 217 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR 276
SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR
Sbjct: 121 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR 180
Query: 277 GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVN 336
GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVN
Sbjct: 181 GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVN 240
Query: 337 AASGGVQNSGIVREAPATSIATVLPQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDS 396
AASGGVQNSGIVREAPATSIATVLPQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDS
Sbjct: 241 AASGGVQNSGIVREAPATSIATVLPQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDS 300
Query: 397 GKNQDFSSFDDTGKSSLGDMFSPIRDDAVVNKGSDESIGKGDGFDFLPQLNSVFPPRKNP 456
GKNQDFSSFDDTGKSSLGDMFSPIRDDAVVNKGSDESIGKGDGFDFLPQLNSVFPPRKNP
Sbjct: 301 GKNQDFSSFDDTGKSSLGDMFSPIRDDAVVNKGSDESIGKGDGFDFLPQLNSVFPPRKNP 360
Query: 457 VTSSTSVLHSSPLNVFMGSPGKEENENRDLTAESKKIYMGKQESKDSFKQLAKLVTSGAE 516
VTSSTSVLHSSPLNVFMGSPGKEENENRDLTAESKKIYMGKQESKDSFKQLAKLVTSGAE
Sbjct: 361 VTSSTSVLHSSPLNVFMGSPGKEENENRDLTAESKKIYMGKQESKDSFKQLAKLVTSGAE 420
Query: 517 SGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPPINGSSTPNPKIASSVTAGVASSLSE 576
SGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPPINGSSTPNPKIASSVTAGVASSLSE
Sbjct: 421 SGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPPINGSSTPNPKIASSVTAGVASSLSE 480
Query: 577 KIADSIGNNRQNAPLTSIQIRFIQNMIQETLDDFREACHRDIVNLQVEMIKQFHMQLNEM 636
KIADSIGNNRQNAPLTSIQIRFIQNMIQETLDDFREACHRDIVNLQVEMIKQFHMQLNEM
Sbjct: 481 KIADSIGNNRQNAPLTSIQIRFIQNMIQETLDDFREACHRDIVNLQVEMIKQFHMQLNEM 540
Query: 637 HSLLERYSVNEGLVAEIERLREENKRLRAHF 667
HSLLERYSVNEGLVAEIERLREENKRLRAHF
Sbjct: 541 HSLLERYSVNEGLVAEIERLREENKRLRAHF 571
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 80.5 bits (197), Expect = 5e-15
Identities = 77/254 (30%), Positives = 113/254 (44%), Gaps = 25/254 (9%)
Query: 15 ASSGDD--IKIWDASSMTLVDKFNPHTSPH--GISSICWSSNNNFLVTASSSGDKIV--- 67
ASS D IKIW A KF S H GIS + WSS++N LV+AS DK +
Sbjct: 61 ASSSADKLIKIWGAYD----GKFEKTISGHKLGISDVAWSSDSNLLVSASD--DKTLKIW 114
Query: 68 -VSSCKCKPVPLLELAEGQKQT--CVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKD 124
VSS KC L+ +G C N N S +VSG + +V IWD+K+ + ++L
Sbjct: 115 DVSSGKC-----LKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPA 169
Query: 125 HKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSL 184
H D V+ V +N + I S S G + + N V +K+S K +
Sbjct: 170 HSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYI 229
Query: 185 LGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGIC--FSPVNELLFVTIGLDKRIILYD 242
L + DN + LWD + + HK I FS V+ D + +++
Sbjct: 230 LAATLDN-TLKLWDYSKGKCLKTYTG-HKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWN 287
Query: 243 TSSKKLVKTLVADT 256
+K++V+ L T
Sbjct: 288 LQTKEIVQKLQGHT 301
Score = 50.4 bits (119), Expect = 5e-06
Identities = 49/223 (21%), Positives = 96/223 (43%), Gaps = 9/223 (4%)
Query: 90 VNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGE 149
V + +L S + + IW + +++ HK ++ V ++ + + S S
Sbjct: 51 VKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKT 110
Query: 150 IILHSVTT-NLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNF 208
+ + V++ T GH + + + +L+ S S + V +WDV +
Sbjct: 111 LKIWDVSSGKCLKTLKGHSNYVFCCNFNP---QSNLIVSGSFDESVRIWDVKTGKCLKTL 167
Query: 209 DSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVAD--TPLTAVDFMPD 266
+ H P S + F+ L+ V+ D ++DT+S + +KTL+ D P++ V F P+
Sbjct: 168 PA-HSDPVSAVHFNRDGSLI-VSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPN 225
Query: 267 GATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYS 309
G + + + +D K +KT + HK CI +S
Sbjct: 226 GKYILAATLDNTLKLWDYSKGKC-LKTYTGHKNEKYCIFANFS 267
Score = 44.7 bits (104), Expect = 3e-04
Identities = 39/147 (26%), Positives = 71/147 (48%), Gaps = 14/147 (9%)
Query: 11 NLRFASSGDDI-KIWDASS----MTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDK 65
+L +SS D + +IWD +S TL+D NP +S + +S N +++ A+
Sbjct: 184 SLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP-----VSFVKFSPNGKYILAATLDNTL 238
Query: 66 IVVSSCKCKPVPLLELAEGQKQTCVNLNST---SMYLVSGGLNNTVNIWDLKSKRVHRSL 122
+ K K + + +K C+ N + ++VSG +N V IW+L++K + + L
Sbjct: 239 KLWDYSKGKCLKTYTGHKNEKY-CIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKL 297
Query: 123 KDHKDQVTCVTYNWNDCYIASGSLSGE 149
+ H D V + + IAS +L +
Sbjct: 298 QGHTDVVISTACHPTENIIASAALEND 324
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 80.5 bits (197), Expect = 5e-15
Identities = 77/254 (30%), Positives = 113/254 (44%), Gaps = 25/254 (9%)
Query: 15 ASSGDD--IKIWDASSMTLVDKFNPHTSPH--GISSICWSSNNNFLVTASSSGDKIV--- 67
ASS D IKIW A KF S H GIS + WSS++N LV+AS DK +
Sbjct: 61 ASSSADKLIKIWGAYD----GKFEKTISGHKLGISDVAWSSDSNLLVSASD--DKTLKIW 114
Query: 68 -VSSCKCKPVPLLELAEGQKQT--CVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKD 124
VSS KC L+ +G C N N S +VSG + +V IWD+K+ + ++L
Sbjct: 115 DVSSGKC-----LKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPA 169
Query: 125 HKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSL 184
H D V+ V +N + I S S G + + N V +K+S K +
Sbjct: 170 HSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYI 229
Query: 185 LGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGIC--FSPVNELLFVTIGLDKRIILYD 242
L + DN + LWD + + HK I FS V+ D + +++
Sbjct: 230 LAATLDN-TLKLWDYSKGKCLKTYTG-HKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWN 287
Query: 243 TSSKKLVKTLVADT 256
+K++V+ L T
Sbjct: 288 LQTKEIVQKLQGHT 301
Score = 50.4 bits (119), Expect = 5e-06
Identities = 49/223 (21%), Positives = 96/223 (43%), Gaps = 9/223 (4%)
Query: 90 VNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGE 149
V + +L S + + IW + +++ HK ++ V ++ + + S S
Sbjct: 51 VKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKT 110
Query: 150 IILHSVTT-NLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNF 208
+ + V++ T GH + + + +L+ S S + V +WDV +
Sbjct: 111 LKIWDVSSGKCLKTLKGHSNYVFCCNFNP---QSNLIVSGSFDESVRIWDVKTGKCLKTL 167
Query: 209 DSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVAD--TPLTAVDFMPD 266
+ H P S + F+ L+ V+ D ++DT+S + +KTL+ D P++ V F P+
Sbjct: 168 PA-HSDPVSAVHFNRDGSLI-VSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPN 225
Query: 267 GATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYS 309
G + + + +D K +KT + HK CI +S
Sbjct: 226 GKYILAATLDNTLKLWDYSKGKC-LKTYTGHKNEKYCIFANFS 267
Score = 44.7 bits (104), Expect = 3e-04
Identities = 39/147 (26%), Positives = 71/147 (48%), Gaps = 14/147 (9%)
Query: 11 NLRFASSGDDI-KIWDASS----MTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDK 65
+L +SS D + +IWD +S TL+D NP +S + +S N +++ A+
Sbjct: 184 SLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP-----VSFVKFSPNGKYILAATLDNTL 238
Query: 66 IVVSSCKCKPVPLLELAEGQKQTCVNLNST---SMYLVSGGLNNTVNIWDLKSKRVHRSL 122
+ K K + + +K C+ N + ++VSG +N V IW+L++K + + L
Sbjct: 239 KLWDYSKGKCLKTYTGHKNEKY-CIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKL 297
Query: 123 KDHKDQVTCVTYNWNDCYIASGSLSGE 149
+ H D V + + IAS +L +
Sbjct: 298 QGHTDVVISTACHPTENIIASAALEND 324
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 73.2 bits (178), Expect = 7e-13
Identities = 62/237 (26%), Positives = 108/237 (45%), Gaps = 14/237 (5%)
Query: 47 ICWSSNNNFLVTASSSGDKIVVSSCKC--------KPVPLLELAEGQKQT-CVNLNSTSM 97
+ +SN + LV +SG + C KP ++ L V LN+
Sbjct: 17 VAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEE 76
Query: 98 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTT 157
+V+G + ++ +WDL++ ++ R+L HK + + ++ ++ASGS I L +
Sbjct: 77 LIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR 136
Query: 158 NLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPAS 217
+ G +Q+VR L++S K L S +D+ V LWD+ + F H P +
Sbjct: 137 KGCVFRY-RGHSQAVRCLRFSPDGK-WLASAADDHTVKLWDLTAGKMMSEFPG-HTGPVN 193
Query: 218 GICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADT-PLTAVDFMPDGATLAIG 273
+ F P NE L + D+ I +D ++V + + P+ +V F PDG L G
Sbjct: 194 VVEFHP-NEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSG 249
Score = 54.3 bits (129), Expect = 4e-07
Identities = 58/211 (27%), Positives = 89/211 (42%), Gaps = 10/211 (4%)
Query: 99 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSV-TT 157
L +GG + VN+W + SL H V V N + I +GS SG I + +
Sbjct: 36 LATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAA 95
Query: 158 NLSSTPFGHGSNQ-SVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 216
+ T GH +N S+ Y F S GS N + LWD+ + + H
Sbjct: 96 KILRTLMGHKANICSLDFHPYGEFVAS--GSQDTN--IKLWDIRRKGCVFRYRG-HSQAV 150
Query: 217 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADT-PLTAVDFMPDGATLAIGSS 275
+ FSP + L + D + L+D ++ K++ T P+ V+F P+ LA GSS
Sbjct: 151 RCLRFSPDGKWL-ASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSS 209
Query: 276 RGKIYQYDLRMLKSPVKTISAHKTSVQCIAF 306
I +DL + V I V+ + F
Sbjct: 210 DRTIRFWDLEKFQ-VVSCIEGEPGPVRSVLF 239
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 68.6 bits (166), Expect = 2e-11
Identities = 61/221 (27%), Positives = 99/221 (44%), Gaps = 17/221 (7%)
Query: 44 ISSICWSSNNNFLVTASSSGDKIV----VSSCKCKPVPLLELAEGQKQT--CVNLNSTSM 97
IS + WSS+++ LV+AS DK + V S KC L+ +G C N N S
Sbjct: 86 ISDVAWSSDSSRLVSASD--DKTLKLWDVRSGKC-----LKTLKGHSNYVFCCNFNPPSN 138
Query: 98 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTT 157
++SG + TV IW++K+ + ++L H D V+ V +N + I SGS G + +
Sbjct: 139 LIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAAS 198
Query: 158 NLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPAS 217
N V +K+S K +L + DN + LWD + + HK
Sbjct: 199 GQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDN-TLKLWDYSRGRCLKTYTG-HKNEKY 256
Query: 218 GIC--FSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADT 256
I FS V+ D + +++ +K++V+ L T
Sbjct: 257 CIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHT 297
Score = 45.8 bits (107), Expect = 1e-04
Identities = 40/139 (28%), Positives = 67/139 (48%), Gaps = 21/139 (15%)
Query: 22 KIWDASS----MTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIV--VSSCKCKP 75
+IWDA+S TLVD NP +S + +S N +++TA+ + S +C
Sbjct: 192 RIWDAASGQCLKTLVDDDNPP-----VSFVKFSPNGKYILTATLDNTLKLWDYSRGRC-- 244
Query: 76 VPLLELAEGQKQT--CVNLNST---SMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVT 130
L+ G K C+ N + ++VSG +N V IW+L++K + + L+ H D V
Sbjct: 245 ---LKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVI 301
Query: 131 CVTYNWNDCYIASGSLSGE 149
+ + IAS +L +
Sbjct: 302 SAACHPTENLIASAALEND 320
Score = 35.4 bits (80), Expect = 0.17
Identities = 39/155 (25%), Positives = 66/155 (42%), Gaps = 5/155 (3%)
Query: 167 GSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNE 226
G ++V +K+S + L S +D ++ +W Y H S + +S +
Sbjct: 39 GHTEAVSSVKFSPNGEWLASSSADR-LIIIWGAYD-GKYEKTLYGHNLEISDVAWSSDSS 96
Query: 227 LLFVTIGLDKRIILYDTSSKKLVKTLVADTPLT-AVDFMPDGATLAIGSSRGKIYQYDLR 285
L V+ DK + L+D S K +KTL + +F P + GS + ++++
Sbjct: 97 RL-VSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVK 155
Query: 286 MLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKG 320
K +KT+SAH V + F S L S G
Sbjct: 156 TGKC-LKTLSAHSDPVSAVHFNCSGSLIVSGSYDG 189
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 67.4 bits (163), Expect = 4e-11
Identities = 78/317 (24%), Positives = 135/317 (42%), Gaps = 31/317 (9%)
Query: 88 TCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLS 147
TCV+ + + L SG +++ + +W +K + HKD VTCV ++ + +ASGS
Sbjct: 23 TCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRD 82
Query: 148 GEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHN 207
+ + ST F +VR + + +S + + SD+ V +W + Q +
Sbjct: 83 KTVRIWVPNVKGESTVF-RAHTATVRSVHFCSDGQSFV-TASDDKTVKVWATHRQKFLFS 140
Query: 208 FDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTP-LTAVDFMPD 266
S H FSP L+ V+ DK + L+D SS++ V + +T VDF P
Sbjct: 141 L-SQHINWVRCAKFSPDGRLI-VSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPS 198
Query: 267 GATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYS-----TVLTKSSLN--- 318
G +A + +D+R + ++ H +V ++F S T + S+L
Sbjct: 199 GTCIAAAGMDNTVKVWDVRTHRL-LQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILD 257
Query: 319 ----------KGCSNKPTTVNKRSVNVNAASGGVQNSGIVREAPATSI----ATVLPQP- 363
G TTV ASGG +V ++ + T +P+P
Sbjct: 258 LMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSNFDIVDHGEVTKVPRPP 317
Query: 364 --MTSAMGKGTVAVQEK 378
+ S+MG TV++ E+
Sbjct: 318 ATLASSMGNLTVSILEQ 334
>gi|48762926 PWP2 periodic tryptophan protein homolog [Homo sapiens]
Length = 919
Score = 65.9 bits (159), Expect = 1e-10
Identities = 55/250 (22%), Positives = 108/250 (43%), Gaps = 13/250 (5%)
Query: 40 SPHGISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPLLELAEGQKQTCVNLNSTSMYL 99
S I+S+ +S+ +++ S +++V + + L + + + Y+
Sbjct: 329 SDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYI 388
Query: 100 VSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNL 159
V+GG + V +W+ S + +H VT VT+ + + S+ G + +
Sbjct: 389 VTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYR 448
Query: 160 SSTPFGHGSNQSVRHLKYSLFKKSLLGSV-----SDNGIVTLWDVNSQSPYHNFDSVHKA 214
+ F S R ++S G + D+ + +W + + + S H+
Sbjct: 449 NFRTF-----TSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQT-GRLLDVLSGHEG 502
Query: 215 PASGICFSPVNELLFVTIGLDKRIILYDT-SSKKLVKTLVADTPLTAVDFMPDGATLAIG 273
P SG+CF+P+ +L + DK + L+D S + +TL + AV F PDGA LA+
Sbjct: 503 PISGLCFNPMKSVL-ASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRPDGAELAVA 561
Query: 274 SSRGKIYQYD 283
+ +I +D
Sbjct: 562 TLNSQITFWD 571
Score = 30.0 bits (66), Expect = 7.2
Identities = 32/143 (22%), Positives = 58/143 (40%), Gaps = 3/143 (2%)
Query: 168 SNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNEL 227
S+QS+ + + + S G + +W+ S+S Y H + +SP +
Sbjct: 329 SDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSES-YVLKQQGHFNSMVALAYSPDGQY 387
Query: 228 LFVTIGLDKRIILYDTSSKKLVKTLVADTP-LTAVDFMPDGATLAIGSSRGKIYQYDLRM 286
+ VT G D ++ +++T S T + +T V F G + S G + +DL
Sbjct: 388 I-VTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHR 446
Query: 287 LKSPVKTISAHKTSVQCIAFQYS 309
++ S T C+A S
Sbjct: 447 YRNFRTFTSPRPTQFSCVAVDAS 469
>gi|189571685 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 65.5 bits (158), Expect = 2e-10
Identities = 63/271 (23%), Positives = 117/271 (43%), Gaps = 35/271 (12%)
Query: 42 HGISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVS 101
+ + C+S + + L + S+ G ++ ++ + + ++E G + S L S
Sbjct: 55 YAVHCCCFSPSGHILASCSTDGTTVLWNTENGQMLAVMEQPSGSPVRVCQFSPDSTCLAS 114
Query: 102 GGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEI--------ILH 153
G + TV +W+ +S +++R + ++ N + +GS G++ LH
Sbjct: 115 GAADGTVVLWNAQSYKLYRCGSVKDGSLAACAFSPNGSFFVTGSSCGDLTVWDDKMRCLH 174
Query: 154 S--------VTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVN----- 200
S + SS P G Q ++ + L S + V +W V+
Sbjct: 175 SEKAHDLGITCCDFSSQPVSDG-EQGLQFFR--------LASCGQDCQVKIWIVSFTHIL 225
Query: 201 -SQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTP-L 258
+ Y + S H AP FS ++L V+ +DK +I+YDT+++ ++ TL T +
Sbjct: 226 GFELKYKSTLSGHCAPVLACAFSHDGQML-VSGSVDKSVIVYDTNTENILHTLTQHTRYV 284
Query: 259 TAVDFMPDGATLAIGS--SRGKIYQYDLRML 287
T F P+ LA GS I+Q+DL L
Sbjct: 285 TTCAFAPNTLLLATGSMDKTVNIWQFDLETL 315
>gi|189571683 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 65.5 bits (158), Expect = 2e-10
Identities = 63/271 (23%), Positives = 117/271 (43%), Gaps = 35/271 (12%)
Query: 42 HGISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVS 101
+ + C+S + + L + S+ G ++ ++ + + ++E G + S L S
Sbjct: 55 YAVHCCCFSPSGHILASCSTDGTTVLWNTENGQMLAVMEQPSGSPVRVCQFSPDSTCLAS 114
Query: 102 GGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEI--------ILH 153
G + TV +W+ +S +++R + ++ N + +GS G++ LH
Sbjct: 115 GAADGTVVLWNAQSYKLYRCGSVKDGSLAACAFSPNGSFFVTGSSCGDLTVWDDKMRCLH 174
Query: 154 S--------VTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVN----- 200
S + SS P G Q ++ + L S + V +W V+
Sbjct: 175 SEKAHDLGITCCDFSSQPVSDG-EQGLQFFR--------LASCGQDCQVKIWIVSFTHIL 225
Query: 201 -SQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTP-L 258
+ Y + S H AP FS ++L V+ +DK +I+YDT+++ ++ TL T +
Sbjct: 226 GFELKYKSTLSGHCAPVLACAFSHDGQML-VSGSVDKSVIVYDTNTENILHTLTQHTRYV 284
Query: 259 TAVDFMPDGATLAIGS--SRGKIYQYDLRML 287
T F P+ LA GS I+Q+DL L
Sbjct: 285 TTCAFAPNTLLLATGSMDKTVNIWQFDLETL 315
>gi|189571681 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 65.5 bits (158), Expect = 2e-10
Identities = 63/271 (23%), Positives = 117/271 (43%), Gaps = 35/271 (12%)
Query: 42 HGISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVS 101
+ + C+S + + L + S+ G ++ ++ + + ++E G + S L S
Sbjct: 55 YAVHCCCFSPSGHILASCSTDGTTVLWNTENGQMLAVMEQPSGSPVRVCQFSPDSTCLAS 114
Query: 102 GGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEI--------ILH 153
G + TV +W+ +S +++R + ++ N + +GS G++ LH
Sbjct: 115 GAADGTVVLWNAQSYKLYRCGSVKDGSLAACAFSPNGSFFVTGSSCGDLTVWDDKMRCLH 174
Query: 154 S--------VTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVN----- 200
S + SS P G Q ++ + L S + V +W V+
Sbjct: 175 SEKAHDLGITCCDFSSQPVSDG-EQGLQFFR--------LASCGQDCQVKIWIVSFTHIL 225
Query: 201 -SQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTP-L 258
+ Y + S H AP FS ++L V+ +DK +I+YDT+++ ++ TL T +
Sbjct: 226 GFELKYKSTLSGHCAPVLACAFSHDGQML-VSGSVDKSVIVYDTNTENILHTLTQHTRYV 284
Query: 259 TAVDFMPDGATLAIGS--SRGKIYQYDLRML 287
T F P+ LA GS I+Q+DL L
Sbjct: 285 TTCAFAPNTLLLATGSMDKTVNIWQFDLETL 315
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 63.9 bits (154), Expect = 4e-10
Identities = 57/223 (25%), Positives = 101/223 (45%), Gaps = 6/223 (2%)
Query: 88 TCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLS 147
TCV+ + + L SG +++ + +W +K + HKD VTCV ++ + +ASGS
Sbjct: 23 TCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRD 82
Query: 148 GEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHN 207
+ + ST F +VR + + +S + + SD+ V +W + Q +
Sbjct: 83 KTVRIWVPNVKGESTVF-RAHTATVRSVHFCSDGQSFV-TASDDKTVKVWATHRQKFLFS 140
Query: 208 FDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTP-LTAVDFMPD 266
S H FSP L+ V+ DK + L+D SS++ V + +T VDF P
Sbjct: 141 L-SQHINWVRCAKFSPDGRLI-VSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPS 198
Query: 267 GATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYS 309
G +A + +D+R + ++ H +V ++F S
Sbjct: 199 GTCIAAAGMDNTVKVWDVRTHRL-LQHYQLHSAAVNGLSFHPS 240
Score = 41.6 bits (96), Expect = 0.002
Identities = 42/167 (25%), Positives = 71/167 (42%), Gaps = 5/167 (2%)
Query: 118 VHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKY 177
+ R K H+D VTCV ++ N +ASGS+ +++ + + F G +V + +
Sbjct: 11 LERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRF-TGHKDAVTCVNF 69
Query: 178 SLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKR 237
S LL S S + V +W N + F H A + F + FVT DK
Sbjct: 70 SP-SGHLLASGSRDKTVRIWVPNVKGESTVF-RAHTATVRSVHFCSDGQ-SFVTASDDKT 126
Query: 238 IILYDTSSKKLVKTLVADTP-LTAVDFMPDGATLAIGSSRGKIYQYD 283
+ ++ T +K + +L + F PDG + S + +D
Sbjct: 127 VKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD 173
Score = 40.4 bits (93), Expect = 0.005
Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 3/97 (3%)
Query: 15 ASSGDDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIVVSSCKCK 74
A + +K+WD + L+ + H++ ++ + + + N+L+TASS ++ + +
Sbjct: 205 AGMDNTVKVWDVRTHRLLQHYQLHSA--AVNGLSFHPSGNYLITASSDSTLKILDLMEGR 262
Query: 75 PVPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIW 111
+ L +G T V + T Y SGG + V +W
Sbjct: 263 LLYTLHGHQGPATT-VAFSRTGEYFASGGSDEQVMVW 298
Score = 38.1 bits (87), Expect = 0.026
Identities = 35/157 (22%), Positives = 71/157 (45%), Gaps = 8/157 (5%)
Query: 14 FASSGDD--IKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIVVSSC 71
F ++ DD +K+W + + H + + +S + +V+AS DK V
Sbjct: 118 FVTASDDKTVKVWATHRQKFLFSLSQHIN--WVRCAKFSPDGRLIVSASD--DKTVKLWD 173
Query: 72 KCKPVPLLELAE-GQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVT 130
K + E G T V+ + + + + G++NTV +WD+++ R+ + + H V
Sbjct: 174 KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVN 233
Query: 131 CVTYNWNDCYIASGSLSGEI-ILHSVTTNLSSTPFGH 166
++++ + Y+ + S + IL + L T GH
Sbjct: 234 GLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGH 270
>gi|11321585 guanine nucleotide-binding protein, beta-1 subunit
[Homo sapiens]
Length = 340
Score = 63.5 bits (153), Expect = 6e-10
Identities = 67/268 (25%), Positives = 107/268 (39%), Gaps = 14/268 (5%)
Query: 44 ISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGG 103
I ++ W +++ LV+AS G I+ S V + L TC S + Y+ GG
Sbjct: 58 IYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN-YVACGG 116
Query: 104 LNNTVNIWDLKSK----RVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNL 159
L+N +I++LK++ RV R L H ++C + +D I + S L + T
Sbjct: 117 LDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRF-LDDNQIVTSSGDTTCALWDIETGQ 175
Query: 160 SSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGI 219
+T F G V L + + + D LWDV F H++ + I
Sbjct: 176 QTTTF-TGHTGDVMSLSLAPDTRLFVSGACD-ASAKLWDVREGMCRQTFTG-HESDINAI 232
Query: 220 CFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADT---PLTAVDFMPDGATLAIGSSR 276
CF P N F T D L+D + + + T D +T+V F G L G
Sbjct: 233 CFFP-NGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDD 291
Query: 277 GKIYQYDLRMLKSPVKTISAHKTSVQCI 304
+D + ++ H V C+
Sbjct: 292 FNCNVWD-ALKADRAGVLAGHDNRVSCL 318
Score = 34.7 bits (78), Expect = 0.29
Identities = 42/162 (25%), Positives = 67/162 (41%), Gaps = 34/162 (20%)
Query: 4 TGAVMQENLR-----FASSGDDI--KIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFL 56
TG VM +L F S D K+WD F H S I++IC+ N N
Sbjct: 184 TGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESD--INAICFFPNGNAF 241
Query: 57 VTASSSGDKIVVSSCKCKPVPLLELAEGQKQ------------TCVNLNSTSMYLVSGGL 104
T S ++C+ L +L Q+ T V+ + + L++G
Sbjct: 242 ATGSDD------ATCR-----LFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYD 290
Query: 105 NNTVNIWD-LKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGS 145
+ N+WD LK+ R L H ++V+C+ + +A+GS
Sbjct: 291 DFNCNVWDALKADRAG-VLAGHDNRVSCLGVTDDGMAVATGS 331
Score = 29.6 bits (65), Expect = 9.4
Identities = 26/113 (23%), Positives = 49/113 (43%), Gaps = 21/113 (18%)
Query: 43 GISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPLLELAEGQKQTC----------VNL 92
G S C ++N +VT SSGD ++C L ++ GQ+ T ++L
Sbjct: 144 GYLSCCRFLDDNQIVT--SSGD----TTCA-----LWDIETGQQTTTFTGHTGDVMSLSL 192
Query: 93 NSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGS 145
+ VSG + + +WD++ ++ H+ + + + N A+GS
Sbjct: 193 APDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGS 245
>gi|113865883 WD repeat domain 38 [Homo sapiens]
Length = 314
Score = 61.6 bits (148), Expect = 2e-09
Identities = 74/264 (28%), Positives = 118/264 (44%), Gaps = 28/264 (10%)
Query: 24 WDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIV----VSSCKCKPVPLL 79
W+ S L+ + HT P C S + L AS+S D V V+ KC L
Sbjct: 48 WETRSGQLLWRLGGHTGP---VKFCRFSPDGHLF-ASASCDCTVRLWDVARAKC-----L 98
Query: 80 ELAEGQKQTC--VNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWN 137
+ +G +++ V+ + S L SGG + V +WD++S ++ R L H+D + ++
Sbjct: 99 RVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPT 158
Query: 138 DCYIASGSLSGEI---ILHSVTTNLSSTPF-GHGSNQSVRHLKYSLFKKSLLGSVSDNGI 193
+A+GS + L VT +S GH +N S L YS LL S S +
Sbjct: 159 VNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANISC--LCYS--ASGLLASGSWDKT 214
Query: 194 VTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTL- 252
+ +W + S H I FSP +EL + G + + ++D ++ K ++TL
Sbjct: 215 IHIWKPTTSSLLIQLKG-HVTWVKSIAFSP-DELWLASAGYSRMVKVWDCNTGKCLETLK 272
Query: 253 -VADTPLTAVDFMPDGATLAIGSS 275
V D T F PDG L G++
Sbjct: 273 GVLDVAHTCA-FTPDGKILVSGAA 295
Score = 57.0 bits (136), Expect = 5e-08
Identities = 44/148 (29%), Positives = 73/148 (49%), Gaps = 6/148 (4%)
Query: 184 LLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDT 243
L S S + V LWDV +++ H+ + FSP + L + G DKR++L+D
Sbjct: 77 LFASASCDCTVRLWDV-ARAKCLRVLKGHQRSVETVSFSPDSRQL-ASGGWDKRVMLWDV 134
Query: 244 SSKKLVKTLVADTP-LTAVDFMPDGATLAIGSSRGKIYQYDLRMLKSPV--KTISAHKTS 300
S ++++ LV + + DF P LA GS ++ +DLRM+ V + + H +
Sbjct: 135 QSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSAN 194
Query: 301 VQCIAFQYSTVLTKSSLNKGCSN-KPTT 327
+ C+ + S +L S +K KPTT
Sbjct: 195 ISCLCYSASGLLASGSWDKTIHIWKPTT 222
>gi|55741849 WD repeat domain 22 [Homo sapiens]
Length = 942
Score = 61.2 bits (147), Expect = 3e-09
Identities = 44/166 (26%), Positives = 80/166 (48%), Gaps = 16/166 (9%)
Query: 89 CVNL----NSTSMYLVSGGLNNTVNIWDLKSKRVHRSLK------DHKDQVTCVTYNWND 138
CVN N+ +LVSGG + V +W ++ + +H +K +H + C+ +N +
Sbjct: 55 CVNAIEFSNNGGQWLVSGGDDRRVLLWHME-QAIHSRVKPIQLKGEHHSNIFCLAFNSGN 113
Query: 139 CYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWD 198
+ SG ++ILH V ++ + F H +V L S ++ S SD+G V +WD
Sbjct: 114 TKVFSGGNDEQVILHDVESSETLDVFAH--EDAVYGLSVSPVNDNIFASSSDDGRVLIWD 171
Query: 199 VNSQSPYHNFDSVHKAPAS--GICFSPVNELLFVTIGLDKRIILYD 242
+ +SP+ + P++ + F+PV L T + + L+D
Sbjct: 172 IR-ESPHGEPFCLANYPSAFHSVMFNPVEPRLLATANSKEGVGLWD 216
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 61.2 bits (147), Expect = 3e-09
Identities = 51/250 (20%), Positives = 106/250 (42%), Gaps = 18/250 (7%)
Query: 4 TGAVMQEN-------LRFASSGDDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFL 56
+GAVM+ + L AS+ + +WD+ + V + HTS + C+ +
Sbjct: 109 SGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTS---FVNSCYPARRGPQ 165
Query: 57 VTASSSGDKIVVSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSK 116
+ + S D V K + + V N TS ++SGG++N + +WDL+
Sbjct: 166 LVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQN 225
Query: 117 RVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLK 176
++ +++ H D VT ++ + Y+ S ++ + + V +V + +
Sbjct: 226 KLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFE 285
Query: 177 YSLFK------KSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFV 230
+L + S + + S + V +WD S+ + H + + F P +E + +
Sbjct: 286 KNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPG-HAGSINEVAFHP-DEPIII 343
Query: 231 TIGLDKRIIL 240
+ DKR+ +
Sbjct: 344 SASSDKRLYM 353
Score = 43.1 bits (100), Expect = 8e-04
Identities = 56/264 (21%), Positives = 104/264 (39%), Gaps = 41/264 (15%)
Query: 44 ISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGG 103
+ + ++++ + L +AS+ V S + V L+ +C + +G
Sbjct: 112 VMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGS 171
Query: 104 LNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTN-LSST 162
+ TV +WD++ K ++ ++ QV VT+N I SG + +I + + N L+ T
Sbjct: 172 DDGTVKLWDIRKKAAIQTFQNTY-QVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYT 230
Query: 163 PFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFS 222
GH SV L S LL + DN V +WDV +P
Sbjct: 231 MRGHAD--SVTGLSLSSEGSYLLSNAMDN-TVRVWDVRPFAPK----------------- 270
Query: 223 PVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSRGKIYQY 282
++ + ++ + K L+ + PDG+ +A GS+ +Y +
Sbjct: 271 ------------ERCVKIFQGNVHNFEKNLLR------CSWSPDGSKIAAGSADRFVYVW 312
Query: 283 DLRMLKSPVKTISAHKTSVQCIAF 306
D + K + H S+ +AF
Sbjct: 313 DTTSRRILYK-LPGHAGSINEVAF 335
>gi|4504053 guanine nucleotide-binding protein, beta-3 subunit [Homo
sapiens]
Length = 340
Score = 56.6 bits (135), Expect = 7e-08
Identities = 67/269 (24%), Positives = 111/269 (41%), Gaps = 16/269 (5%)
Query: 44 ISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGG 103
I ++ W++++ LV+AS G IV S V + L TC S + ++ GG
Sbjct: 58 IYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN-FVACGG 116
Query: 104 LNNTVNIWDLKSK----RVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNL 159
L+N +I++LKS+ +V R L H ++C + +D I + S L + T
Sbjct: 117 LDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRF-LDDNNIVTSSGDTTCALWDIETGQ 175
Query: 160 SSTPF-GHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASG 218
T F GH + + +L S + + LWDV + F H++ +
Sbjct: 176 QKTVFVGHTGDCMSLAVSPDF---NLFISGACDASAKLWDVREGTCRQTFTG-HESDINA 231
Query: 219 ICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADT---PLTAVDFMPDGATLAIGSS 275
ICF P E + T D L+D + + + ++ +T+V F G L G
Sbjct: 232 ICFFPNGEAI-CTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYD 290
Query: 276 RGKIYQYDLRMLKSPVKTISAHKTSVQCI 304
+D M V +S H V C+
Sbjct: 291 DFNCNVWD-SMKSERVGILSGHDNRVSCL 318
Score = 37.7 bits (86), Expect = 0.034
Identities = 36/137 (26%), Positives = 59/137 (43%), Gaps = 27/137 (19%)
Query: 22 KIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPLLEL 81
K+WD T F H S I++IC+ N + T S +SC+ L +L
Sbjct: 209 KLWDVREGTCRQTFTGHESD--INAICFFPNGEAICTGSDD------ASCR-----LFDL 255
Query: 82 AEGQKQTCVNLNS------------TSMYLVSGGLNNTVNIWD-LKSKRVHRSLKDHKDQ 128
Q+ C + S + L +G + N+WD +KS+RV L H ++
Sbjct: 256 RADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVG-ILSGHDNR 314
Query: 129 VTCVTYNWNDCYIASGS 145
V+C+ + +A+GS
Sbjct: 315 VSCLGVTADGMAVATGS 331
Score = 32.0 bits (71), Expect = 1.9
Identities = 39/177 (22%), Positives = 73/177 (41%), Gaps = 24/177 (13%)
Query: 34 KFNPHTSPH-GISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPLLELAEGQKQT---- 88
K + S H G S C ++N +VT SSGD ++C L ++ GQ++T
Sbjct: 134 KVSRELSAHTGYLSCCRFLDDNNIVT--SSGD----TTCA-----LWDIETGQQKTVFVG 182
Query: 89 ----CVNLNSTSMY--LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIA 142
C++L + + +SG + + +WD++ ++ H+ + + + N I
Sbjct: 183 HTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAIC 242
Query: 143 SGSLSGEIILHSVTTNLSSTPFGHGS-NQSVRHLKYSLFKKSLLGSVSDNGIVTLWD 198
+GS L + + F H S + + +SL + L D +WD
Sbjct: 243 TGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFN-CNVWD 298
>gi|20357529 guanine nucleotide-binding protein, beta-2 subunit
[Homo sapiens]
Length = 340
Score = 55.8 bits (133), Expect = 1e-07
Identities = 64/268 (23%), Positives = 106/268 (39%), Gaps = 14/268 (5%)
Query: 44 ISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGG 103
I ++ W +++ LV+AS G I+ S V + L TC S + ++ GG
Sbjct: 58 IYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN-FVACGG 116
Query: 104 LNNTVNIWDLKSK----RVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNL 159
L+N +I+ LK++ RV R L H ++C + +D I + S L + T
Sbjct: 117 LDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRF-LDDNQIITSSGDTTCALWDIETGQ 175
Query: 160 SSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGI 219
+ F G + V L + ++ + D I LWDV F H++ + +
Sbjct: 176 QTVGFA-GHSGDVMSLSLAPDGRTFVSGACDASI-KLWDVRDSMCRQTFIG-HESDINAV 232
Query: 220 CFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADT---PLTAVDFMPDGATLAIGSSR 276
F P N F T D L+D + + + D +T+V F G L G
Sbjct: 233 AFFP-NGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDD 291
Query: 277 GKIYQYDLRMLKSPVKTISAHKTSVQCI 304
+D M ++ H V C+
Sbjct: 292 FNCNIWD-AMKGDRAGVLAGHDNRVSCL 318
>gi|102470001 PQQ repeat and WD repeat domain containing [Homo
sapiens]
Length = 472
Score = 54.3 bits (129), Expect = 4e-07
Identities = 44/136 (32%), Positives = 67/136 (49%), Gaps = 18/136 (13%)
Query: 21 IKIWDASSM-TLVDKFNPHTSPHGISSICWSSNNNFLVTAS----------SSGDKIVVS 69
IKIWD +S TL+ H++ IS+ C++ + +FL T+S +G+
Sbjct: 254 IKIWDVTSQATLLTITKAHSN--AISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNCG 311
Query: 70 SCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQV 129
+C V L++ EG +C + S +L+SGG + TV IWD+ SLK H D V
Sbjct: 312 AC----VTLMQGHEGSVSSC-HFARDSSFLISGGFDRTVAIWDVAEGYRKLSLKGHNDWV 366
Query: 130 TCVTYNWNDCYIASGS 145
V + N +I S S
Sbjct: 367 MDVAISNNKKWILSAS 382
Score = 32.3 bits (72), Expect = 1.4
Identities = 32/117 (27%), Positives = 48/117 (41%), Gaps = 4/117 (3%)
Query: 159 LSSTPFG--HGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 216
LS PF G +V + + LL S S + V LWD S +F+ KAP
Sbjct: 90 LSKIPFKILSGHEHAVSTCHFCVDDTKLL-SGSYDCTVKLWDPVDGSVVRDFEHRPKAPV 148
Query: 217 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIG 273
C + + DK + +D + KL+ + DT + + F PDG + G
Sbjct: 149 VE-CSITGDSSRVIAASYDKTVRAWDLETGKLLWKVRYDTFIVSCKFSPDGKYVVSG 204
Score = 30.8 bits (68), Expect = 4.2
Identities = 31/154 (20%), Positives = 63/154 (40%), Gaps = 6/154 (3%)
Query: 91 NLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEI 150
++ S +++ + TV WDL++ ++ ++ V+C ++ + Y+ SG
Sbjct: 152 SITGDSSRVIAASYDKTVRAWDLETGKLLWKVRYDTFIVSC-KFSPDGKYVVSGFDVDHG 210
Query: 151 ILHSVTTNLSSTPFGHGSNQSVRHLKYSLFK--KSLLGSVSDNGIVTLWDVNSQSPYHNF 208
I N+++ + R + F + SVS + + +WDV SQ+
Sbjct: 211 ICIMDAENITTVSVI--KDHHTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTI 268
Query: 209 DSVHKAPASGICFSPVNELLFVTIGLDKRIILYD 242
H S CF+ L T DK + +++
Sbjct: 269 TKAHSNAISNCCFTFSGHFL-CTSSWDKNLKIWN 301
>gi|48928050 F-box and WD repeat domain containing 11 isoform C
[Homo sapiens]
Length = 542
Score = 53.9 bits (128), Expect = 5e-07
Identities = 56/239 (23%), Positives = 107/239 (44%), Gaps = 21/239 (8%)
Query: 85 QKQTCVNLNSTSMY--------LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNW 136
Q+ C + NS +Y ++SG +N++ IWD S + L H V C+ Y
Sbjct: 231 QRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY-- 288
Query: 137 NDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTL 196
++ I +GS + + V T H N++V HL++S L+ + S + + +
Sbjct: 289 DERVIVTGSSDSTVRVWDVNTGEVLNTLIH-HNEAVLHLRFS---NGLMVTCSKDRSIAV 344
Query: 197 WDVNSQS--PYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVA 254
WD+ S + H+A + + F ++ V+ D+ I ++ TS+ + V+TL
Sbjct: 345 WDMASATDITLRRVLVGHRAAVNVVDF---DDKYIVSASGDRTIKVWSTSTCEFVRTLNG 401
Query: 255 DTPLTAVDFMPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLT 313
A D ++ GSS I +D+ + ++ + H+ V+CI F +++
Sbjct: 402 HKRGIACLQYRDRLVVS-GSSDNTIRLWDIE-CGACLRVLEGHEELVRCIRFDNKRIVS 458
Score = 45.8 bits (107), Expect = 1e-04
Identities = 40/157 (25%), Positives = 72/157 (45%), Gaps = 15/157 (9%)
Query: 1 MHFTGAVMQENLRFA-------SSGDDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNN 53
+H AV+ +LRF+ S I +WD +S T + ++ ++
Sbjct: 317 IHHNEAVL--HLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVV-DFDD 373
Query: 54 NFLVTASSSGDKIVVSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDL 113
++V+AS V S+ C+ V L G K+ L +VSG +NT+ +WD+
Sbjct: 374 KYIVSASGDRTIKVWSTSTCEFVRTLN---GHKRGIACLQYRDRLVVSGSSDNTIRLWDI 430
Query: 114 KSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEI 150
+ R L+ H++ V C+ + ++ I SG+ G+I
Sbjct: 431 ECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKI 465
Score = 43.5 bits (101), Expect = 6e-04
Identities = 43/184 (23%), Positives = 77/184 (41%), Gaps = 16/184 (8%)
Query: 19 DDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPL 78
+ IKIWD +S+ + HT S +C + +VT SS V +
Sbjct: 260 NSIKIWDKTSLECLKVLTGHTG----SVLCLQYDERVIVTGSSDS---TVRVWDVNTGEV 312
Query: 79 LELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSK---RVHRSLKDHKDQVTCVTYN 135
L + ++L ++ +V+ + ++ +WD+ S + R L H+ V V +
Sbjct: 313 LNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVV--D 370
Query: 136 WNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVT 195
++D YI S S I + S +T F N R + ++ L+ S S + +
Sbjct: 371 FDDKYIVSASGDRTIKVWSTST----CEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIR 426
Query: 196 LWDV 199
LWD+
Sbjct: 427 LWDI 430
Score = 35.0 bits (79), Expect = 0.22
Identities = 55/291 (18%), Positives = 110/291 (37%), Gaps = 26/291 (8%)
Query: 42 HGISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPL--------LELAEGQKQTCVNLN 93
H + I S N+ V D+ ++S + + + L++ G + + L
Sbjct: 228 HNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQ 287
Query: 94 STSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILH 153
+V+G ++TV +WD+ + V +L H + V + ++ S S +
Sbjct: 288 YDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDM 347
Query: 154 SVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHK 213
+ T+++ G +V + F + S S + + +W ++ + HK
Sbjct: 348 ASATDITLRRVLVGHRAAVNVVD---FDDKYIVSASGDRTIKVWSTSTCEFVRTLNG-HK 403
Query: 214 APASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLT-AVDFMPDGATLAI 272
GI + L V+ D I L+D ++ L L + F D +
Sbjct: 404 ---RGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVS 458
Query: 273 GSSRGKIYQYDLRMLKSP--------VKTISAHKTSVQCIAFQYSTVLTKS 315
G+ GKI +DL+ P ++T+ H V + F +++ S
Sbjct: 459 GAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSS 509
>gi|48928048 F-box and WD repeat domain containing 11 isoform A
[Homo sapiens]
Length = 508
Score = 53.9 bits (128), Expect = 5e-07
Identities = 56/239 (23%), Positives = 107/239 (44%), Gaps = 21/239 (8%)
Query: 85 QKQTCVNLNSTSMY--------LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNW 136
Q+ C + NS +Y ++SG +N++ IWD S + L H V C+ Y
Sbjct: 197 QRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY-- 254
Query: 137 NDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTL 196
++ I +GS + + V T H N++V HL++S L+ + S + + +
Sbjct: 255 DERVIVTGSSDSTVRVWDVNTGEVLNTLIH-HNEAVLHLRFS---NGLMVTCSKDRSIAV 310
Query: 197 WDVNSQS--PYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVA 254
WD+ S + H+A + + F ++ V+ D+ I ++ TS+ + V+TL
Sbjct: 311 WDMASATDITLRRVLVGHRAAVNVVDF---DDKYIVSASGDRTIKVWSTSTCEFVRTLNG 367
Query: 255 DTPLTAVDFMPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLT 313
A D ++ GSS I +D+ + ++ + H+ V+CI F +++
Sbjct: 368 HKRGIACLQYRDRLVVS-GSSDNTIRLWDIE-CGACLRVLEGHEELVRCIRFDNKRIVS 424
Score = 45.8 bits (107), Expect = 1e-04
Identities = 40/157 (25%), Positives = 72/157 (45%), Gaps = 15/157 (9%)
Query: 1 MHFTGAVMQENLRFA-------SSGDDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNN 53
+H AV+ +LRF+ S I +WD +S T + ++ ++
Sbjct: 283 IHHNEAVL--HLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVV-DFDD 339
Query: 54 NFLVTASSSGDKIVVSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDL 113
++V+AS V S+ C+ V L G K+ L +VSG +NT+ +WD+
Sbjct: 340 KYIVSASGDRTIKVWSTSTCEFVRTLN---GHKRGIACLQYRDRLVVSGSSDNTIRLWDI 396
Query: 114 KSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEI 150
+ R L+ H++ V C+ + ++ I SG+ G+I
Sbjct: 397 ECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKI 431
Score = 43.5 bits (101), Expect = 6e-04
Identities = 43/184 (23%), Positives = 77/184 (41%), Gaps = 16/184 (8%)
Query: 19 DDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPL 78
+ IKIWD +S+ + HT S +C + +VT SS V +
Sbjct: 226 NSIKIWDKTSLECLKVLTGHTG----SVLCLQYDERVIVTGSSDS---TVRVWDVNTGEV 278
Query: 79 LELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSK---RVHRSLKDHKDQVTCVTYN 135
L + ++L ++ +V+ + ++ +WD+ S + R L H+ V V +
Sbjct: 279 LNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVV--D 336
Query: 136 WNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVT 195
++D YI S S I + S +T F N R + ++ L+ S S + +
Sbjct: 337 FDDKYIVSASGDRTIKVWSTST----CEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIR 392
Query: 196 LWDV 199
LWD+
Sbjct: 393 LWDI 396
Score = 35.0 bits (79), Expect = 0.22
Identities = 55/291 (18%), Positives = 110/291 (37%), Gaps = 26/291 (8%)
Query: 42 HGISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPL--------LELAEGQKQTCVNLN 93
H + I S N+ V D+ ++S + + + L++ G + + L
Sbjct: 194 HNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQ 253
Query: 94 STSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILH 153
+V+G ++TV +WD+ + V +L H + V + ++ S S +
Sbjct: 254 YDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDM 313
Query: 154 SVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHK 213
+ T+++ G +V + F + S S + + +W ++ + HK
Sbjct: 314 ASATDITLRRVLVGHRAAVNVVD---FDDKYIVSASGDRTIKVWSTSTCEFVRTLNG-HK 369
Query: 214 APASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLT-AVDFMPDGATLAI 272
GI + L V+ D I L+D ++ L L + F D +
Sbjct: 370 ---RGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVS 424
Query: 273 GSSRGKIYQYDLRMLKSP--------VKTISAHKTSVQCIAFQYSTVLTKS 315
G+ GKI +DL+ P ++T+ H V + F +++ S
Sbjct: 425 GAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSS 475
>gi|48928046 F-box and WD repeat domain containing 11 isoform B
[Homo sapiens]
Length = 529
Score = 53.9 bits (128), Expect = 5e-07
Identities = 56/239 (23%), Positives = 107/239 (44%), Gaps = 21/239 (8%)
Query: 85 QKQTCVNLNSTSMY--------LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNW 136
Q+ C + NS +Y ++SG +N++ IWD S + L H V C+ Y
Sbjct: 218 QRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY-- 275
Query: 137 NDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTL 196
++ I +GS + + V T H N++V HL++S L+ + S + + +
Sbjct: 276 DERVIVTGSSDSTVRVWDVNTGEVLNTLIH-HNEAVLHLRFS---NGLMVTCSKDRSIAV 331
Query: 197 WDVNSQS--PYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVA 254
WD+ S + H+A + + F ++ V+ D+ I ++ TS+ + V+TL
Sbjct: 332 WDMASATDITLRRVLVGHRAAVNVVDF---DDKYIVSASGDRTIKVWSTSTCEFVRTLNG 388
Query: 255 DTPLTAVDFMPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLT 313
A D ++ GSS I +D+ + ++ + H+ V+CI F +++
Sbjct: 389 HKRGIACLQYRDRLVVS-GSSDNTIRLWDIE-CGACLRVLEGHEELVRCIRFDNKRIVS 445
Score = 45.8 bits (107), Expect = 1e-04
Identities = 40/157 (25%), Positives = 72/157 (45%), Gaps = 15/157 (9%)
Query: 1 MHFTGAVMQENLRFA-------SSGDDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNN 53
+H AV+ +LRF+ S I +WD +S T + ++ ++
Sbjct: 304 IHHNEAVL--HLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVV-DFDD 360
Query: 54 NFLVTASSSGDKIVVSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDL 113
++V+AS V S+ C+ V L G K+ L +VSG +NT+ +WD+
Sbjct: 361 KYIVSASGDRTIKVWSTSTCEFVRTLN---GHKRGIACLQYRDRLVVSGSSDNTIRLWDI 417
Query: 114 KSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEI 150
+ R L+ H++ V C+ + ++ I SG+ G+I
Sbjct: 418 ECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKI 452
Score = 43.5 bits (101), Expect = 6e-04
Identities = 43/184 (23%), Positives = 77/184 (41%), Gaps = 16/184 (8%)
Query: 19 DDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPL 78
+ IKIWD +S+ + HT S +C + +VT SS V +
Sbjct: 247 NSIKIWDKTSLECLKVLTGHTG----SVLCLQYDERVIVTGSSDS---TVRVWDVNTGEV 299
Query: 79 LELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSK---RVHRSLKDHKDQVTCVTYN 135
L + ++L ++ +V+ + ++ +WD+ S + R L H+ V V +
Sbjct: 300 LNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVV--D 357
Query: 136 WNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVT 195
++D YI S S I + S +T F N R + ++ L+ S S + +
Sbjct: 358 FDDKYIVSASGDRTIKVWSTST----CEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIR 413
Query: 196 LWDV 199
LWD+
Sbjct: 414 LWDI 417
Score = 35.0 bits (79), Expect = 0.22
Identities = 55/291 (18%), Positives = 110/291 (37%), Gaps = 26/291 (8%)
Query: 42 HGISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPL--------LELAEGQKQTCVNLN 93
H + I S N+ V D+ ++S + + + L++ G + + L
Sbjct: 215 HNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQ 274
Query: 94 STSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILH 153
+V+G ++TV +WD+ + V +L H + V + ++ S S +
Sbjct: 275 YDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDM 334
Query: 154 SVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHK 213
+ T+++ G +V + F + S S + + +W ++ + HK
Sbjct: 335 ASATDITLRRVLVGHRAAVNVVD---FDDKYIVSASGDRTIKVWSTSTCEFVRTLNG-HK 390
Query: 214 APASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLT-AVDFMPDGATLAI 272
GI + L V+ D I L+D ++ L L + F D +
Sbjct: 391 ---RGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVS 445
Query: 273 GSSRGKIYQYDLRMLKSP--------VKTISAHKTSVQCIAFQYSTVLTKS 315
G+ GKI +DL+ P ++T+ H V + F +++ S
Sbjct: 446 GAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSS 496
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 53.5 bits (127), Expect = 6e-07
Identities = 60/265 (22%), Positives = 109/265 (41%), Gaps = 11/265 (4%)
Query: 15 ASSGDDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIVVSSCKCK 74
ASSG+ +W+ + H SP + ++ WS N+ +++TA G +
Sbjct: 138 ASSGE-FTLWNGLTFNFETILQAHDSP--VRAMTWSHNDMWMLTADHGG-YVKYWQSNMN 193
Query: 75 PVPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTY 134
V + + A + + + T + + TV IWD R L+ H V CV +
Sbjct: 194 NVKMFQ-AHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDW 252
Query: 135 NWNDCYIASGSLSGE--IILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNG 192
+ + SGS + I T S H +V +K +L LL + D+
Sbjct: 253 HPTKGLVVSGSKDSQQPIKFWDPKTGQSLATL-HAHKNTVMEVKLNLNGNWLLTASRDH- 310
Query: 193 IVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLV--K 250
+ L+D+ + HK A+ + + PV+E LF + G D ++ + +K V
Sbjct: 311 LCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWHVGVEKEVGGM 370
Query: 251 TLVADTPLTAVDFMPDGATLAIGSS 275
+ + + ++ + P G L GS+
Sbjct: 371 EMAHEGMIWSLAWHPLGHILCSGSN 395
Score = 36.6 bits (83), Expect = 0.077
Identities = 42/211 (19%), Positives = 85/211 (40%), Gaps = 8/211 (3%)
Query: 99 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTN 158
LV+G + +W+ + L+ H V +T++ ND ++ + G + +N
Sbjct: 134 LVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQ--SN 191
Query: 159 LSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASG 218
+++ +++R +S + + SD+G V +WD + H A
Sbjct: 192 MNNVKMFQAHKEAIREASFSP-TDNKFATCSDDGTVRIWDF-LRCHEERILRGHGADVKC 249
Query: 219 ICFSPVNELLFVTIGLDKR--IILYDTSSKKLVKTLVA-DTPLTAVDFMPDGATLAIGSS 275
+ + P L+ V+ D + I +D + + + TL A + V +G L S
Sbjct: 250 VDWHPTKGLV-VSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASR 308
Query: 276 RGKIYQYDLRMLKSPVKTISAHKTSVQCIAF 306
+D+R LK ++ HK +A+
Sbjct: 309 DHLCKLFDIRNLKEELQVFRGHKKEATAVAW 339
>gi|5174447 guanine nucleotide binding protein (G protein), beta
polypeptide 2-like 1 [Homo sapiens]
Length = 317
Score = 53.1 bits (126), Expect = 8e-07
Identities = 47/193 (24%), Positives = 85/193 (44%), Gaps = 9/193 (4%)
Query: 99 LVSGGLNNTVNIWDLKSKRVH-----RSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILH 153
++S + T+ +W L + R+L+ H V+ V + + + SGS G + L
Sbjct: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
Query: 154 SVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHK 213
+TT ++ F G + V + +S + ++ D + LW+ Y D H
Sbjct: 91 DLTTGTTTRRF-VGHTKDVLSVAFSSDNRQIVSGSRDK-TIKLWNTLGVCKYTVQDESHS 148
Query: 214 APASGICFSP-VNELLFVTIGLDKRIILYDTSSKKLVKTLVADTP-LTAVDFMPDGATLA 271
S + FSP + + V+ G DK + +++ ++ KL + T L V PDG+ A
Sbjct: 149 EWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCA 208
Query: 272 IGSSRGKIYQYDL 284
G G+ +DL
Sbjct: 209 SGGKDGQAMLWDL 221
Score = 43.1 bits (100), Expect = 8e-04
Identities = 51/229 (22%), Positives = 96/229 (41%), Gaps = 14/229 (6%)
Query: 90 VNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGE 149
V ++S + +SG + T+ +WDL + R H V V ++ ++ I SGS
Sbjct: 69 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 128
Query: 150 IILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKS-LLGSVSDNGIVTLWDVNSQSPYHNF 208
I L + T ++ V +++S + ++ S + +V +W++ + N
Sbjct: 129 IKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNH 188
Query: 209 DSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPD-- 266
H + + SP L + G D + +L+D + K + TL + A+ F P+
Sbjct: 189 IG-HTGYLNTVTVSPDGSLC-ASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRY 246
Query: 267 ------GATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYS 309
G ++ I GKI + LK V + S+ QC + +S
Sbjct: 247 WLCAATGPSIKIWDLEGKII---VDELKQEVISTSSKAEPPQCTSLAWS 292
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 52.4 bits (124), Expect = 1e-06
Identities = 31/124 (25%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Query: 22 KIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPLLEL 81
K+WDA++ V H I C+ + TAS+ G + S+ K + LE
Sbjct: 286 KLWDATNGKCVATLTGHDDE--ILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEG 343
Query: 82 AEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYI 141
EG+ ++ N +L++G + T IWD ++ + + L+ H D++ +N+ +
Sbjct: 344 HEGEISK-ISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIV 402
Query: 142 ASGS 145
+GS
Sbjct: 403 ITGS 406
Score = 50.1 bits (118), Expect = 7e-06
Identities = 47/234 (20%), Positives = 97/234 (41%), Gaps = 10/234 (4%)
Query: 89 CVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSG 148
C++ N S + +G ++ T +WD+++ +L+ H ++ +++N + I +GS
Sbjct: 182 CLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDH 241
Query: 149 EIILHSVTTNLS-STPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHN 207
+++ T + GH + S + SL+ + S + LWD +
Sbjct: 242 TVVVWDADTGRKVNILIGHCAEISSASFNWDC---SLILTGSMDKTCKLWDATNGKCVAT 298
Query: 208 FDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVA-DTPLTAVDFMPD 266
H CF +L+ T D ++ +++K + L + ++ + F P
Sbjct: 299 LTG-HDDEILDSCFDYTGKLI-ATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQ 356
Query: 267 GATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQY--STVLTKSSLN 318
G L GSS +D + + ++ + H + AF Y + V+T S N
Sbjct: 357 GNHLLTGSSDKTARIWDAQTGQC-LQVLEGHTDEIFSCAFNYKGNIVITGSKDN 409
Score = 48.5 bits (114), Expect = 2e-05
Identities = 51/236 (21%), Positives = 99/236 (41%), Gaps = 9/236 (3%)
Query: 88 TCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYN--WNDCYIASGS 145
T V LN + ++G + T +WD S +L+ H++ V + +N + D IA+GS
Sbjct: 96 TNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGD-KIATGS 154
Query: 146 LSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPY 205
L SV T F G + L ++ + +L+ + S + LWD+ +
Sbjct: 155 FDKTCKLWSVETGKCYHTF-RGHTAEIVCLSFNP-QSTLVATGSMDTTAKLWDIQNGEEV 212
Query: 206 HNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVAD-TPLTAVDFM 264
+ H A + F+ + + +T D ++++D + + V L+ +++ F
Sbjct: 213 YTLRG-HSAEIISLSFNTSGDRI-ITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFN 270
Query: 265 PDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKG 320
D + + GS +D K V T++ H + F Y+ L ++ G
Sbjct: 271 WDCSLILTGSMDKTCKLWDATNGKC-VATLTGHDDEILDSCFDYTGKLIATASADG 325
Score = 46.6 bits (109), Expect = 7e-05
Identities = 52/244 (21%), Positives = 103/244 (42%), Gaps = 11/244 (4%)
Query: 79 LELAEGQKQTCVNLNSTSMY---LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYN 135
L EG + + + Y + +G + T +W +++ + + + + H ++ C+++N
Sbjct: 127 LNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFN 186
Query: 136 WNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVT 195
+A+GS+ L + N G + + L ++ ++ D+ +V
Sbjct: 187 PQSTLVATGSMDTTAKLWDI-QNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVV- 244
Query: 196 LWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVA- 254
+WD ++ N H A S F+ + L +T +DK L+D ++ K V TL
Sbjct: 245 VWDADTGRKV-NILIGHCAEISSASFN-WDCSLILTGSMDKTCKLWDATNGKCVATLTGH 302
Query: 255 DTPLTAVDFMPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAF--QYSTVL 312
D + F G +A S+ G + K K + H+ + I+F Q + +L
Sbjct: 303 DDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAK-LEGHEGEISKISFNPQGNHLL 361
Query: 313 TKSS 316
T SS
Sbjct: 362 TGSS 365
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 52.0 bits (123), Expect = 2e-06
Identities = 51/207 (24%), Positives = 92/207 (44%), Gaps = 6/207 (2%)
Query: 104 LNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTP 163
+++ + +W +K + HKD VTCV ++ + +ASGS + + ST
Sbjct: 1 MDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTV 60
Query: 164 FGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSP 223
F +VR + + +S + + SD+ V +W + Q + S H FSP
Sbjct: 61 F-RAHTATVRSVHFCSDGQSFV-TASDDKTVKVWATHRQKFLFSL-SQHINWVRCAKFSP 117
Query: 224 VNELLFVTIGLDKRIILYDTSSKKLVKTLVADTP-LTAVDFMPDGATLAIGSSRGKIYQY 282
L+ V+ DK + L+D SS++ V + +T VDF P G +A + +
Sbjct: 118 DGRLI-VSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVW 176
Query: 283 DLRMLKSPVKTISAHKTSVQCIAFQYS 309
D+R + ++ H +V ++F S
Sbjct: 177 DVRTHRL-LQHYQLHSAAVNGLSFHPS 202
Score = 47.0 bits (110), Expect = 6e-05
Identities = 71/309 (22%), Positives = 122/309 (39%), Gaps = 29/309 (9%)
Query: 88 TCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLS 147
TCVN + + L SG + TV IW K + H V V + S S
Sbjct: 27 TCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSV-------HFCSDGQS 79
Query: 148 GEIILHSVTTNLSST---PFGHGSNQSVRHLKYSLFKKS--LLGSVSDNGIVTLWDVNSQ 202
T + +T F +Q + ++ + F L+ S SD+ V LWD +S+
Sbjct: 80 FVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSR 139
Query: 203 SPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTL-VADTPLTAV 261
H++ H + + F P + G+D + ++D + +L++ + + +
Sbjct: 140 ECVHSY-CEHGGFVTYVDFHPSGTCI-AAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGL 197
Query: 262 DFMPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKGC 321
F P G L SS + DL M + T+ H+ +AF T G
Sbjct: 198 SFHPSGNYLITASSDSTLKILDL-MEGRLLYTLHGHQGPATTVAFS----RTGEYFASGG 252
Query: 322 SNKPTTVNKRSVNVNAASGGVQNSGIVREAPATSIATV--LPQ---PMTSAMGKGTVAVQ 376
S++ V K + ++ G V V PAT +++ LP+ P+ G+ +VQ
Sbjct: 253 SDEQVMVWKSNFDI-VDHGEVTK---VPRPPATLASSMGNLPEVDFPVPPGRGRSVESVQ 308
Query: 377 EKAGLPRSI 385
+ P S+
Sbjct: 309 SQPQEPVSV 317
Score = 38.1 bits (87), Expect = 0.026
Identities = 35/157 (22%), Positives = 71/157 (45%), Gaps = 8/157 (5%)
Query: 14 FASSGDD--IKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIVVSSC 71
F ++ DD +K+W + + H + + +S + +V+AS DK V
Sbjct: 80 FVTASDDKTVKVWATHRQKFLFSLSQHIN--WVRCAKFSPDGRLIVSASD--DKTVKLWD 135
Query: 72 KCKPVPLLELAE-GQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVT 130
K + E G T V+ + + + + G++NTV +WD+++ R+ + + H V
Sbjct: 136 KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVN 195
Query: 131 CVTYNWNDCYIASGSLSGEI-ILHSVTTNLSSTPFGH 166
++++ + Y+ + S + IL + L T GH
Sbjct: 196 GLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGH 232
>gi|13376840 WD repeat domain 61 [Homo sapiens]
Length = 305
Score = 51.6 bits (122), Expect = 2e-06
Identities = 66/286 (23%), Positives = 119/286 (41%), Gaps = 28/286 (9%)
Query: 10 ENLRFASSGDDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIV-- 67
E + S D +K+W L +++ G+ S+ ++ + ASSS D +
Sbjct: 33 ETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSV--DISHTLPIAASSSLDAHIRL 90
Query: 68 --------VSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVH 119
+ S PV LA + S YL +G VNI+ ++S +
Sbjct: 91 WDLENGKQIKSIDAGPVDAWTLA---------FSPDSQYLATGTHVGKVNIFGVESGKKE 141
Query: 120 RSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTT-NLSSTPFGHGSNQSVRHLKYS 178
SL + + Y+ + Y+ASG++ G I + + T L T GH +R L +S
Sbjct: 142 YSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHA--MPIRSLTFS 199
Query: 179 LFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRI 238
LL + SD+G + ++DV + S H + + F P ++ FV+ DK +
Sbjct: 200 P-DSQLLVTASDDGYIKIYDVQHANLAGTL-SGHASWVLNVAFCP-DDTHFVSSSSDKSV 256
Query: 239 ILYDTSSKKLVKTLV-ADTPLTAVDFMPDGATLAIGSSRGKIYQYD 283
++D ++ V T + V + +G+ + +I+ YD
Sbjct: 257 KVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302
Score = 47.0 bits (110), Expect = 6e-05
Identities = 57/219 (26%), Positives = 96/219 (43%), Gaps = 8/219 (3%)
Query: 91 NLNSTSMYLVSGGLNNTVNIWDLKSKRVHR--SLKDHKDQVTCVTYNWNDCYIASGSLSG 148
N S +V+G L++ V +W + +R+ SL+ H+ V V + AS SL
Sbjct: 27 NKKENSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDA 86
Query: 149 EIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNF 208
I L + G + L +S L + + G V ++ V S ++
Sbjct: 87 HIRLWDLENGKQIKSIDAGPVDAWT-LAFSP-DSQYLATGTHVGKVNIFGVESGKKEYSL 144
Query: 209 DSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADT-PLTAVDFMPDG 267
D+ K S I +SP + L + +D I ++D ++ KL+ TL P+ ++ F PD
Sbjct: 145 DTRGKFILS-IAYSPDGKYL-ASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDS 202
Query: 268 ATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAF 306
L S G I YD++ + T+S H + V +AF
Sbjct: 203 QLLVTASDDGYIKIYDVQH-ANLAGTLSGHASWVLNVAF 240
>gi|4502477 beta-transducin repeat containing protein isoform 2
[Homo sapiens]
Length = 569
Score = 51.2 bits (121), Expect = 3e-06
Identities = 51/217 (23%), Positives = 98/217 (45%), Gaps = 13/217 (5%)
Query: 99 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTN 158
+VSG +NT+ IWD + R L H V C+ Y ++ I +GS + + V T
Sbjct: 280 IVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVRVWDVNTG 337
Query: 159 LSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQS--PYHNFDSVHKAPA 216
H ++V HL+ F ++ + S + + +WD+ S + H+A
Sbjct: 338 EMLNTLIHHC-EAVLHLR---FNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAV 393
Query: 217 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR 276
+ + F ++ V+ D+ I +++TS+ + V+TL A D ++ GSS
Sbjct: 394 NVVDF---DDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVS-GSSD 449
Query: 277 GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLT 313
I +D+ + ++ + H+ V+CI F +++
Sbjct: 450 NTIRLWDIE-CGACLRVLEGHEELVRCIRFDNKRIVS 485
Score = 48.5 bits (114), Expect = 2e-05
Identities = 45/212 (21%), Positives = 84/212 (39%), Gaps = 19/212 (8%)
Query: 16 SSGDDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIVVSSCKCKP 75
SS +++WD ++ +++ H + + NN +VT S V
Sbjct: 324 SSDSTVRVWDVNTGEMLNTLIHHCE----AVLHLRFNNGMMVTCSKDRSIAVWDMASPTD 379
Query: 76 VPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYN 135
+ L + G + ++ Y+VS + T+ +W+ + R+L HK + C+ Y
Sbjct: 380 ITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQY- 438
Query: 136 WNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVT 195
D + SGS I L + G + VR +++ K ++ D G +
Sbjct: 439 -RDRLVVSGSSDNTIRLWDIECGACLRVL-EGHEELVRCIRFD--NKRIVSGAYD-GKIK 493
Query: 196 LWD-VNSQSPYHNFDSVHKAPASGICFSPVNE 226
+WD V + P +APA +C + E
Sbjct: 494 VWDLVAALDP--------RAPAGTLCLRTLVE 517
Score = 36.6 bits (83), Expect = 0.077
Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 8/100 (8%)
Query: 15 ASSGD-DIKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIVVSSCKC 73
++SGD IK+W+ S+ V N H GI+ + + LV + SS + I + +C
Sbjct: 405 SASGDRTIKVWNTSTCEFVRTLNGH--KRGIACLQYRDR---LVVSGSSDNTIRLWDIEC 459
Query: 74 KPVPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDL 113
L + EG ++ + + +VSG + + +WDL
Sbjct: 460 G--ACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDL 497
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,370,851
Number of Sequences: 37866
Number of extensions: 1098442
Number of successful extensions: 4213
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 127
Number of HSP's successfully gapped in prelim test: 208
Number of HSP's that attempted gapping in prelim test: 3296
Number of HSP's gapped (non-prelim): 892
length of query: 667
length of database: 18,247,518
effective HSP length: 109
effective length of query: 558
effective length of database: 14,120,124
effective search space: 7879029192
effective search space used: 7879029192
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.