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Search of human proteins with 205830424
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|205830424 solute carrier family 39 (zinc transporter),
member 14 isoform a [Homo sapiens]
(492 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|205830424 solute carrier family 39 (zinc transporter), member... 988 0.0
gi|190360568 solute carrier family 39 (zinc transporter), member... 988 0.0
gi|190358541 solute carrier family 39 (zinc transporter), member... 949 0.0
gi|205830426 solute carrier family 39 (zinc transporter), member... 894 0.0
gi|24586665 solute carrier family 39 (zinc transporter), member ... 415 e-116
gi|205830403 solute carrier family 39 (zinc transporter), member... 415 e-116
gi|205830407 solute carrier family 39 (zinc transporter), member... 404 e-112
gi|205830405 solute carrier family 39 (zinc transporter), member... 389 e-108
gi|153252201 solute carrier family 39 (zinc transporter), member... 221 2e-57
gi|187936949 solute carrier family 39 (zinc transporter), member... 219 3e-57
gi|55741750 solute carrier family 39 (zinc transporter), member ... 219 3e-57
gi|223633939 solute carrier family 39 (zinc transporter), member... 200 2e-51
gi|115430259 solute carrier family 39 (zinc transporter), member... 197 1e-50
gi|115430255 solute carrier family 39 (zinc transporter), member... 197 1e-50
gi|153252214 solute carrier family 39 (zinc transporter), member... 189 6e-48
gi|223633937 solute carrier family 39 (zinc transporter), member... 186 5e-47
gi|206597541 solute carrier family 39 (metal ion transporter), m... 136 5e-32
gi|206597539 solute carrier family 39 (metal ion transporter), m... 136 5e-32
gi|117553619 solute carrier family 39, member 7 [Homo sapiens] 102 1e-21
gi|117553608 solute carrier family 39, member 7 [Homo sapiens] 102 1e-21
gi|40255101 solute carrier family 39 (zinc transporter), member ... 84 3e-16
gi|190014617 solute carrier family 39 (zinc transporter), member... 80 3e-15
gi|156415986 solute carrier family 39 (zinc transporter), member... 40 0.005
gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo... 38 0.018
gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo... 38 0.018
gi|21361423 solute carrier family 39 (zinc transporter), member ... 35 0.16
gi|118918411 zinc finger protein 777 [Homo sapiens] 32 1.0
gi|189181750 human immunodeficiency virus type I enhancer bindin... 32 1.3
gi|116089331 human immunodeficiency virus type I enhancer bindin... 32 1.3
gi|154689858 SMYD family member 5 [Homo sapiens] 31 2.2
>gi|205830424 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 988 bits (2553), Expect = 0.0
Identities = 492/492 (100%), Positives = 492/492 (100%)
Query: 1 MKLLLLHPAFQSCLLLTLLGLWRTTPEAHASSLGAPAISAASFLQDLIHRYGEGDSLTLQ 60
MKLLLLHPAFQSCLLLTLLGLWRTTPEAHASSLGAPAISAASFLQDLIHRYGEGDSLTLQ
Sbjct: 1 MKLLLLHPAFQSCLLLTLLGLWRTTPEAHASSLGAPAISAASFLQDLIHRYGEGDSLTLQ 60
Query: 61 QLKALLNHLDVGVGRGNVTQHVQGHRNLSTCFSSGDLFTAHNFSEQSRIGSSELQEFCPT 120
QLKALLNHLDVGVGRGNVTQHVQGHRNLSTCFSSGDLFTAHNFSEQSRIGSSELQEFCPT
Sbjct: 61 QLKALLNHLDVGVGRGNVTQHVQGHRNLSTCFSSGDLFTAHNFSEQSRIGSSELQEFCPT 120
Query: 121 ILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKK 180
ILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKK
Sbjct: 121 ILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKK 180
Query: 181 TFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKI 240
TFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKI
Sbjct: 181 TFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKI 240
Query: 241 LKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPM 300
LKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPM
Sbjct: 241 LKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPM 300
Query: 301 VDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFT 360
VDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFT
Sbjct: 301 VDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFT 360
Query: 361 VSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG 420
VSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG
Sbjct: 361 VSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG 420
Query: 421 SHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMV 480
SHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMV
Sbjct: 421 SHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMV 480
Query: 481 VLTMYSGQIQIG 492
VLTMYSGQIQIG
Sbjct: 481 VLTMYSGQIQIG 492
>gi|190360568 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 988 bits (2553), Expect = 0.0
Identities = 492/492 (100%), Positives = 492/492 (100%)
Query: 1 MKLLLLHPAFQSCLLLTLLGLWRTTPEAHASSLGAPAISAASFLQDLIHRYGEGDSLTLQ 60
MKLLLLHPAFQSCLLLTLLGLWRTTPEAHASSLGAPAISAASFLQDLIHRYGEGDSLTLQ
Sbjct: 1 MKLLLLHPAFQSCLLLTLLGLWRTTPEAHASSLGAPAISAASFLQDLIHRYGEGDSLTLQ 60
Query: 61 QLKALLNHLDVGVGRGNVTQHVQGHRNLSTCFSSGDLFTAHNFSEQSRIGSSELQEFCPT 120
QLKALLNHLDVGVGRGNVTQHVQGHRNLSTCFSSGDLFTAHNFSEQSRIGSSELQEFCPT
Sbjct: 61 QLKALLNHLDVGVGRGNVTQHVQGHRNLSTCFSSGDLFTAHNFSEQSRIGSSELQEFCPT 120
Query: 121 ILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKK 180
ILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKK
Sbjct: 121 ILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKK 180
Query: 181 TFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKI 240
TFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKI
Sbjct: 181 TFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKI 240
Query: 241 LKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPM 300
LKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPM
Sbjct: 241 LKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPM 300
Query: 301 VDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFT 360
VDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFT
Sbjct: 301 VDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFT 360
Query: 361 VSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG 420
VSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG
Sbjct: 361 VSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG 420
Query: 421 SHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMV 480
SHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMV
Sbjct: 421 SHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMV 480
Query: 481 VLTMYSGQIQIG 492
VLTMYSGQIQIG
Sbjct: 481 VLTMYSGQIQIG 492
>gi|190358541 solute carrier family 39 (zinc transporter), member 14
isoform b [Homo sapiens]
Length = 492
Score = 949 bits (2452), Expect = 0.0
Identities = 472/492 (95%), Positives = 481/492 (97%)
Query: 1 MKLLLLHPAFQSCLLLTLLGLWRTTPEAHASSLGAPAISAASFLQDLIHRYGEGDSLTLQ 60
MKLLLLHPAFQSCLLLTLLGLWRTTPEAHASSLGAPAISAASFLQDLIHRYGEGDSLTLQ
Sbjct: 1 MKLLLLHPAFQSCLLLTLLGLWRTTPEAHASSLGAPAISAASFLQDLIHRYGEGDSLTLQ 60
Query: 61 QLKALLNHLDVGVGRGNVTQHVQGHRNLSTCFSSGDLFTAHNFSEQSRIGSSELQEFCPT 120
QLKALLNHLDVGVGRGNVTQHVQGHRNLSTCFSSGDLFTAHNFSEQSRIGSSELQEFCPT
Sbjct: 61 QLKALLNHLDVGVGRGNVTQHVQGHRNLSTCFSSGDLFTAHNFSEQSRIGSSELQEFCPT 120
Query: 121 ILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKK 180
ILQQLDSRACTSENQENEENEQTEEGRPSAVEVWG+G L V++I+L SLLG V+P +K
Sbjct: 121 ILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGFGFLSVSLINLASLLGVLVLPCTEK 180
Query: 181 TFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKI 240
F+ R+L YFIAL+IGTL SNALFQLIPEAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKI
Sbjct: 181 AFFSRVLTYFIALSIGTLLSNALFQLIPEAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKI 240
Query: 241 LKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPM 300
LKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPM
Sbjct: 241 LKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPM 300
Query: 301 VDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFT 360
VDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFT
Sbjct: 301 VDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFT 360
Query: 361 VSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG 420
VSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG
Sbjct: 361 VSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG 420
Query: 421 SHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMV 480
SHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMV
Sbjct: 421 SHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMV 480
Query: 481 VLTMYSGQIQIG 492
VLTMYSGQIQIG
Sbjct: 481 VLTMYSGQIQIG 492
>gi|205830426 solute carrier family 39 (zinc transporter), member 14
isoform c [Homo sapiens]
Length = 481
Score = 894 bits (2309), Expect = 0.0
Identities = 444/444 (100%), Positives = 444/444 (100%)
Query: 1 MKLLLLHPAFQSCLLLTLLGLWRTTPEAHASSLGAPAISAASFLQDLIHRYGEGDSLTLQ 60
MKLLLLHPAFQSCLLLTLLGLWRTTPEAHASSLGAPAISAASFLQDLIHRYGEGDSLTLQ
Sbjct: 1 MKLLLLHPAFQSCLLLTLLGLWRTTPEAHASSLGAPAISAASFLQDLIHRYGEGDSLTLQ 60
Query: 61 QLKALLNHLDVGVGRGNVTQHVQGHRNLSTCFSSGDLFTAHNFSEQSRIGSSELQEFCPT 120
QLKALLNHLDVGVGRGNVTQHVQGHRNLSTCFSSGDLFTAHNFSEQSRIGSSELQEFCPT
Sbjct: 61 QLKALLNHLDVGVGRGNVTQHVQGHRNLSTCFSSGDLFTAHNFSEQSRIGSSELQEFCPT 120
Query: 121 ILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKK 180
ILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKK
Sbjct: 121 ILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKK 180
Query: 181 TFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKI 240
TFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKI
Sbjct: 181 TFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKI 240
Query: 241 LKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPM 300
LKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPM
Sbjct: 241 LKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPM 300
Query: 301 VDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFT 360
VDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFT
Sbjct: 301 VDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFT 360
Query: 361 VSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG 420
VSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG
Sbjct: 361 VSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG 420
Query: 421 SHFSANWIFALAGGMFLYISLADM 444
SHFSANWIFALAGGMFLYISLADM
Sbjct: 421 SHFSANWIFALAGGMFLYISLADM 444
>gi|24586665 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 415 bits (1067), Expect = e-116
Identities = 230/466 (49%), Positives = 315/466 (67%), Gaps = 25/466 (5%)
Query: 30 ASSLGAPAISAA-SFLQDLIHRYGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQGHRNL 88
A+ LG A +F +D++ +G SL+ QL+ LL + R V + Q H N
Sbjct: 15 AAGLGGVAEGPGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAA-SRVGVPEPGQLHFN- 72
Query: 89 STCFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRP 148
C ++ ++F+ H FS ++I SS+ CP +LQQL+ C E+ + RP
Sbjct: 73 -QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC--------EDRPKHKTRP 123
Query: 149 SAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIP 208
S EVWGYG L VT+I+L SLLG + P +KK+++ ++L +F+ LAIGTL+SNA+FQLIP
Sbjct: 124 SHSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIP 183
Query: 209 EAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESL-PSKK 267
EAFGF+P D YV K+ VFGGFYL FF E++LK+LLK ++ GH+H+ +++ P +K
Sbjct: 184 EAFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQN--GHTHFGNDNFGPQEK 241
Query: 268 DQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKG 327
+ + + NG + P +E +G + V+ S+QD + S+C LKG
Sbjct: 242 THQPKALPAI-NGVTCYANP--AVTEANGHIHFDNVSVV----SLQDGKKEPSSCTCLKG 294
Query: 328 VRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVI 387
+ S+IGT+AWMITL D LHNFIDGLAIGAS T+S+ QG+STS+AILCEEFPHELGDFVI
Sbjct: 295 PKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVI 354
Query: 388 LLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFSANWIFALAGGMFLYISLADMFPE 447
LLNAGMS +QAL FNFLSAC CY+GLAFGIL G++F+ N IFALAGGMFLYISLADMFPE
Sbjct: 355 LLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPE 414
Query: 448 MNEVCQE--DERKGSILIPFIIQNLGLLTGFTIMVVLTMYSGQIQI 491
MN++ +E RK F+IQN G+LTGFT ++++T+Y+G+I++
Sbjct: 415 MNDMLREKVTGRKTDFTF-FMIQNAGMLTGFTAILLITLYAGEIEL 459
>gi|205830403 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 415 bits (1067), Expect = e-116
Identities = 230/466 (49%), Positives = 315/466 (67%), Gaps = 25/466 (5%)
Query: 30 ASSLGAPAISAA-SFLQDLIHRYGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQGHRNL 88
A+ LG A +F +D++ +G SL+ QL+ LL + R V + Q H N
Sbjct: 15 AAGLGGVAEGPGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAA-SRVGVPEPGQLHFN- 72
Query: 89 STCFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRP 148
C ++ ++F+ H FS ++I SS+ CP +LQQL+ C E+ + RP
Sbjct: 73 -QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC--------EDRPKHKTRP 123
Query: 149 SAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIP 208
S EVWGYG L VT+I+L SLLG + P +KK+++ ++L +F+ LAIGTL+SNA+FQLIP
Sbjct: 124 SHSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIP 183
Query: 209 EAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESL-PSKK 267
EAFGF+P D YV K+ VFGGFYL FF E++LK+LLK ++ GH+H+ +++ P +K
Sbjct: 184 EAFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQN--GHTHFGNDNFGPQEK 241
Query: 268 DQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKG 327
+ + + NG + P +E +G + V+ S+QD + S+C LKG
Sbjct: 242 THQPKALPAI-NGVTCYANP--AVTEANGHIHFDNVSVV----SLQDGKKEPSSCTCLKG 294
Query: 328 VRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVI 387
+ S+IGT+AWMITL D LHNFIDGLAIGAS T+S+ QG+STS+AILCEEFPHELGDFVI
Sbjct: 295 PKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVI 354
Query: 388 LLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFSANWIFALAGGMFLYISLADMFPE 447
LLNAGMS +QAL FNFLSAC CY+GLAFGIL G++F+ N IFALAGGMFLYISLADMFPE
Sbjct: 355 LLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPE 414
Query: 448 MNEVCQE--DERKGSILIPFIIQNLGLLTGFTIMVVLTMYSGQIQI 491
MN++ +E RK F+IQN G+LTGFT ++++T+Y+G+I++
Sbjct: 415 MNDMLREKVTGRKTDFTF-FMIQNAGMLTGFTAILLITLYAGEIEL 459
>gi|205830407 solute carrier family 39 (zinc transporter), member 8
isoform c [Homo sapiens]
Length = 393
Score = 404 bits (1038), Expect = e-112
Identities = 212/404 (52%), Positives = 287/404 (71%), Gaps = 21/404 (5%)
Query: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSA 150
C ++ ++F+ H FS ++I SS+ CP +LQQL+ C E+ + RPS
Sbjct: 7 CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC--------EDRPKHKTRPSH 58
Query: 151 VEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEA 210
EVWGYG L VT+I+L SLLG + P +KK+++ ++L +F+ LAIGTL+SNA+FQLIPEA
Sbjct: 59 SEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEA 118
Query: 211 FGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESL-PSKKDQ 269
FGF+P D YV K+ VFGGFYL FF E++LK+LLK ++ GH+H+ +++ P +K
Sbjct: 119 FGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQN--GHTHFGNDNFGPQEKTH 176
Query: 270 EEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVR 329
+ + + NG + P +E +G + V+ S+QD + S+C LKG +
Sbjct: 177 QPKALPAI-NGVTCYANP--AVTEANGHIHFDNVSVV----SLQDGKKEPSSCTCLKGPK 229
Query: 330 YSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILL 389
S+IGT+AWMITL D LHNFIDGLAIGAS T+S+ QG+STS+AILCEEFPHELGDFVILL
Sbjct: 230 LSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILL 289
Query: 390 NAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFSANWIFALAGGMFLYISLADMFPEMN 449
NAGMS +QAL FNFLSAC CY+GLAFGIL G++F+ N IFALAGGMFLYISLADMFPEMN
Sbjct: 290 NAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMN 349
Query: 450 EVCQE--DERKGSILIPFIIQNLGLLTGFTIMVVLTMYSGQIQI 491
++ +E RK F+IQN G+LTGFT ++++T+Y+G+I++
Sbjct: 350 DMLREKVTGRKTDFTF-FMIQNAGMLTGFTAILLITLYAGEIEL 392
>gi|205830405 solute carrier family 39 (zinc transporter), member 8
isoform b [Homo sapiens]
Length = 444
Score = 389 bits (998), Expect = e-108
Identities = 214/427 (50%), Positives = 288/427 (67%), Gaps = 22/427 (5%)
Query: 30 ASSLGAPAISAA-SFLQDLIHRYGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQGHRNL 88
A+ LG A +F +D++ +G SL+ QL+ LL + R V + Q H N
Sbjct: 15 AAGLGGVAEGPGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAA-SRVGVPEPGQLHFN- 72
Query: 89 STCFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRP 148
C ++ ++F+ H FS ++I SS+ CP +LQQL+ C E+ + RP
Sbjct: 73 -QCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC--------EDRPKHKTRP 123
Query: 149 SAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIP 208
S EVWGYG L VT+I+L SLLG + P +KK+++ ++L +F+ LAIGTL+SNA+FQLIP
Sbjct: 124 SHSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIP 183
Query: 209 EAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESL-PSKK 267
EAFGF+P D YV K+ VFGGFYL FF E++LK+LLK ++ GH+H+ +++ P +K
Sbjct: 184 EAFGFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQN--GHTHFGNDNFGPQEK 241
Query: 268 DQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKG 327
+ + + NG + P +E +G + V+ S+QD + S+C LKG
Sbjct: 242 THQPKALPAI-NGVTCYANP--AVTEANGHIHFDNVSVV----SLQDGKKEPSSCTCLKG 294
Query: 328 VRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVI 387
+ S+IGT+AWMITL D LHNFIDGLAIGAS T+S+ QG+STS+AILCEEFPHELGDFVI
Sbjct: 295 PKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVI 354
Query: 388 LLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFSANWIFALAGGMFLYISLADMFPE 447
LLNAGMS +QAL FNFLSAC CY+GLAFGIL G++F+ N IFALAGGMFLYISLADMFPE
Sbjct: 355 LLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPE 414
Query: 448 MNEVCQE 454
MN++ +E
Sbjct: 415 MNDMLRE 421
>gi|153252201 solute carrier family 39 (zinc transporter), member 6
isoform 1 [Homo sapiens]
Length = 755
Score = 221 bits (562), Expect = 2e-57
Identities = 152/501 (30%), Positives = 232/501 (46%), Gaps = 105/501 (20%)
Query: 85 HRNLSTCFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTE 144
+ N CF++ L T+H Q + ++E CP I+ Q+D+R+C +E+ +
Sbjct: 258 NENPQECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHT--SEKKAEIP 315
Query: 145 EGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALF 204
S W G + +++IS SLLG +VP M + F+K LL + +ALA+GTL +A
Sbjct: 316 PKTYSLQIAWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFL 375
Query: 205 QLIPEAFG--------------------FNPLEDYYVSKSA---------VVFGGFYLFF 235
L+P + F+ L + +SA GG Y F
Sbjct: 376 HLLPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMF 435
Query: 236 FTEKILKILL-----KQKNEH--HHGHSHYASESLPSKKDQEEGVMEKLQNGD------- 281
E +L ++ K+KN+ + + L + Q EK+ D
Sbjct: 436 LVEHVLTLIKQFKDKKKKNQKKPENDDDVEIKKQLSKYESQLSTNEEKVDTDDRTEGYLR 495
Query: 282 LDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQA------------------------ 317
D P H S+ A + +E+V++ Q++
Sbjct: 496 ADSQEPSHFDSQQP--AVLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDD 553
Query: 318 -----------------------SQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLA 354
S S Y + ++ + + TLAWM+ + DGLHNF DGLA
Sbjct: 554 LIHHHHDYHHILHHHHHQNHHPHSHSQRYSREELKDAGVATLAWMVIMGDGLHNFSDGLA 613
Query: 355 IGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLA 414
IGA+FT + G+STSVA+ C E PHELGDF +LL AGM+++QA+ +N LSA YLG+A
Sbjct: 614 IGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMA 673
Query: 415 FGILAGSHFSAN---WIFALAGGMFLYISLADMFPEMNEVCQED---ERKGSILIPFIIQ 468
GI G H++ N WIFAL G+F+Y++L DM PEM D R G F +Q
Sbjct: 674 TGIFIG-HYAENVSMWIFALTAGLFMYVALVDMVPEMLHNDASDHGCSRWGY----FFLQ 728
Query: 469 NLGLLTGFTIMVVLTMYSGQI 489
N G+L GF IM++++++ +I
Sbjct: 729 NAGMLLGFGIMLLISIFEHKI 749
Score = 29.6 bits (65), Expect = 6.5
Identities = 14/36 (38%), Positives = 24/36 (66%), Gaps = 1/36 (2%)
Query: 37 AISAASF-LQDLIHRYGEGDSLTLQQLKALLNHLDV 71
AIS + LQ L +RYGE +SL+++ + LL ++ +
Sbjct: 49 AISTRQYHLQQLFYRYGENNSLSVEGFRKLLQNIGI 84
>gi|187936949 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 219 bits (559), Expect = 3e-57
Identities = 151/490 (30%), Positives = 231/490 (47%), Gaps = 92/490 (18%)
Query: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTS-------ENQENEENEQT 143
C + L + S I + CP +L Q+DSR C E+ ++N
Sbjct: 337 CLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVP 396
Query: 144 EEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNAL 203
E+ W G++ +TVISL SLLG +VP + + +K LL + +ALA+GT+ +AL
Sbjct: 397 EDEANIGASAWICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDAL 456
Query: 204 FQLIPEAFGFNP--------------------LEDY-YVSKSAVVFGGFYLFFFTEKILK 242
L+P + G + LE+Y V K V GG YL F E ++
Sbjct: 457 LHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIR 516
Query: 243 IL-------------LKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQH 289
+ +KQ E + L + D + ++ L D D ++ +
Sbjct: 517 MFKHYKQQRGKQKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLAGTD-DSVVSED 575
Query: 290 CSSE-----LDGKAP--------MVDEKVI-------VGSLSVQDLQA------------ 317
+E L+G+ + +EK+I + ++ DL A
Sbjct: 576 RLNETELTDLEGQQESPPKNYLCIEEEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTV 635
Query: 318 ---------------SQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVS 362
S C+ ++ + I +AWM+ + DG+HNF DGLAIGA+F+
Sbjct: 636 LRKHNHQWHHKHSHHSHGPCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAG 695
Query: 363 VFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSH 422
+ GISTS+A+ C E PHELGDF +LL AGM+++QA+ +N LSA Y+G+ G G +
Sbjct: 696 LTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQY 755
Query: 423 FS--ANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILI-PFIIQNLGLLTGFTIM 479
+ WIFA+ GMFLY++L DM PEM ++E G + FI+QNLGLL GF IM
Sbjct: 756 ANNITLWIFAVTAGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIM 815
Query: 480 VVLTMYSGQI 489
+V+ +Y +I
Sbjct: 816 LVIALYEDKI 825
Score = 29.3 bits (64), Expect = 8.5
Identities = 26/108 (24%), Positives = 46/108 (42%), Gaps = 7/108 (6%)
Query: 43 FLQDLIHRYGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQ-GHRNLS----TCFSSGDL 97
+++ L RYGE L+ L+ LL +L +G + H GH ++S G
Sbjct: 63 YIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEGKH 122
Query: 98 FTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEE 145
F +HN +SE Q T + + C E + E + ++++
Sbjct: 123 FHSHNHQHSHNHLNSENQTV--TSVSTKRNHKCDPEKETVEVSVKSDD 168
>gi|55741750 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 219 bits (559), Expect = 3e-57
Identities = 151/490 (30%), Positives = 231/490 (47%), Gaps = 92/490 (18%)
Query: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTS-------ENQENEENEQT 143
C + L + S I + CP +L Q+DSR C E+ ++N
Sbjct: 337 CLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVP 396
Query: 144 EEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNAL 203
E+ W G++ +TVISL SLLG +VP + + +K LL + +ALA+GT+ +AL
Sbjct: 397 EDEANIGASAWICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDAL 456
Query: 204 FQLIPEAFGFNP--------------------LEDY-YVSKSAVVFGGFYLFFFTEKILK 242
L+P + G + LE+Y V K V GG YL F E ++
Sbjct: 457 LHLLPHSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIR 516
Query: 243 IL-------------LKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQH 289
+ +KQ E + L + D + ++ L D D ++ +
Sbjct: 517 MFKHYKQQRGKQKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLAGTD-DSVVSED 575
Query: 290 CSSE-----LDGKAP--------MVDEKVI-------VGSLSVQDLQA------------ 317
+E L+G+ + +EK+I + ++ DL A
Sbjct: 576 RLNETELTDLEGQQESPPKNYLCIEEEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTV 635
Query: 318 ---------------SQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVS 362
S C+ ++ + I +AWM+ + DG+HNF DGLAIGA+F+
Sbjct: 636 LRKHNHQWHHKHSHHSHGPCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAG 695
Query: 363 VFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSH 422
+ GISTS+A+ C E PHELGDF +LL AGM+++QA+ +N LSA Y+G+ G G +
Sbjct: 696 LTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQY 755
Query: 423 FS--ANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILI-PFIIQNLGLLTGFTIM 479
+ WIFA+ GMFLY++L DM PEM ++E G + FI+QNLGLL GF IM
Sbjct: 756 ANNITLWIFAVTAGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIM 815
Query: 480 VVLTMYSGQI 489
+V+ +Y +I
Sbjct: 816 LVIALYEDKI 825
Score = 29.3 bits (64), Expect = 8.5
Identities = 26/108 (24%), Positives = 46/108 (42%), Gaps = 7/108 (6%)
Query: 43 FLQDLIHRYGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQ-GHRNLS----TCFSSGDL 97
+++ L RYGE L+ L+ LL +L +G + H GH ++S G
Sbjct: 63 YIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEGKH 122
Query: 98 FTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEE 145
F +HN +SE Q T + + C E + E + ++++
Sbjct: 123 FHSHNHQHSHNHLNSENQTV--TSVSTKRNHKCDPEKETVEVSVKSDD 168
>gi|223633939 solute carrier family 39 (zinc transporter), member 12
isoform 1 [Homo sapiens]
Length = 691
Score = 200 bits (509), Expect = 2e-51
Identities = 140/452 (30%), Positives = 228/452 (50%), Gaps = 73/452 (16%)
Query: 75 RGNVTQHVQGHRNLS----------------TCFSSGDLFTAHNFSEQSRIGSSELQEFC 118
+ N+ H Q + N S TCFS+ L S I + ++
Sbjct: 278 QNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMS 337
Query: 119 PTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFM 178
P I+QQL S +C + +Q + P+ +E +GY + VT+++L S+LG ++V F
Sbjct: 338 PGIIQQLLSCSC------HLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFH 391
Query: 179 K-KTFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLE-----DYYVSKSAV-----V 227
+ Y+ +L F+ LA+GTL +AL LIP+ G + E ++ SK + +
Sbjct: 392 SCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGL 451
Query: 228 FGGFYLFFFTEKILKILLKQKNEH-------HHGHSHYASESLPSKKDQEEGVMEKLQNG 280
GG + FF EK +L+ ++ H GHSH+ + L S+ + G +
Sbjct: 452 IGGIHGFFLIEKCFILLVSPNDKQGLSLVNGHVGHSHHLA--LNSELSDQAGRGKS---- 505
Query: 281 DLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMI 340
+S + K+P E + + + AS C I LA MI
Sbjct: 506 ----------ASTIQLKSP---EDSQAAEMPIGSMTASNRKC--------KAISLLAIMI 544
Query: 341 TLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALF 400
+ D LHNF DGLAIGA+F+ S G++T++AILC E PHE+GDF +LL++G+S++ A+
Sbjct: 545 LVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAIL 604
Query: 401 FNFLSACCCYLGLAFGI-LAGSHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKG 459
NF+S+ ++GL G+ ++ +WIF + GMFLY+SL +M PEM V + +R
Sbjct: 605 MNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHV--QTQRPW 662
Query: 460 SILIPFIIQNLGLLTGFTIMVVLTMYSGQIQI 491
+ F++QN GL+ G+ +++L +Y I+I
Sbjct: 663 MM---FLLQNFGLILGWLSLLLLAIYEQNIKI 691
>gi|115430259 solute carrier family 39 (zinc transporter), member 4
isoform 1 [Homo sapiens]
Length = 622
Score = 197 bits (502), Expect = 1e-50
Identities = 148/482 (30%), Positives = 230/482 (47%), Gaps = 76/482 (15%)
Query: 43 FLQDLIHRYGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQGHRNLST------------ 90
F+ + ++ +TL +L AL+ L GVGR + H HR S+
Sbjct: 180 FVDFVFQQHSSEVPMTLAELSALMQRL--GVGREAHSDHSHRHRGASSRDPVPLISSSNS 237
Query: 91 -------CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQT 143
C S+ D+ A+ SEQ+ + + P +LQQ S ACTS+++ +++ +
Sbjct: 238 SSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLS 297
Query: 144 EEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMK---KTFYKRLLLYFIALAIGTLYS 200
+ R + YG L +I LC++ G ++ T Y +L F++LA+G L
Sbjct: 298 QSER------YLYGSLATLLICLCAVFGLLLLTCTGCRGVTHY--ILQTFLSLAVGALTG 349
Query: 201 NALFQLIPEAFGFNPLEDYYVS-----KSAVVFGGFYLFFFTEKILKILLKQKNEH---- 251
+A+ L P+ G + + +S + + G Y FF E + +LL + E
Sbjct: 350 DAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDG 409
Query: 252 ---HHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVG 308
H HSH GV +L +L P H S D A E
Sbjct: 410 PCGHSSHSHGG---------HSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPEL---- 456
Query: 309 SLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGIS 368
L+ + + S ++ L +MITL D +HNF DGLA+GA+F S G++
Sbjct: 457 -LNPEPRRLSP------------ELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLA 503
Query: 369 TSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG-SHFSANW 427
TS+A+ C E PHELGDF LL+AG+S++QAL N SA + GL + G S S W
Sbjct: 504 TSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAW 563
Query: 428 IFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMVVLTMYSG 487
I A+A G+FLY++L DM P M +V D R + F++ N+GLL G+T++++L++Y
Sbjct: 564 ILAVATGLFLYVALCDMLPAMLKV--RDPRPWLL---FLLHNVGLLGGWTVLLLLSLYED 618
Query: 488 QI 489
I
Sbjct: 619 DI 620
>gi|115430255 solute carrier family 39 (zinc transporter), member 4
isoform 2 [Homo sapiens]
Length = 647
Score = 197 bits (502), Expect = 1e-50
Identities = 148/482 (30%), Positives = 230/482 (47%), Gaps = 76/482 (15%)
Query: 43 FLQDLIHRYGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQGHRNLST------------ 90
F+ + ++ +TL +L AL+ L GVGR + H HR S+
Sbjct: 205 FVDFVFQQHSSEVPMTLAELSALMQRL--GVGREAHSDHSHRHRGASSRDPVPLISSSNS 262
Query: 91 -------CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQT 143
C S+ D+ A+ SEQ+ + + P +LQQ S ACTS+++ +++ +
Sbjct: 263 SSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLS 322
Query: 144 EEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMK---KTFYKRLLLYFIALAIGTLYS 200
+ R + YG L +I LC++ G ++ T Y +L F++LA+G L
Sbjct: 323 QSER------YLYGSLATLLICLCAVFGLLLLTCTGCRGVTHY--ILQTFLSLAVGALTG 374
Query: 201 NALFQLIPEAFGFNPLEDYYVS-----KSAVVFGGFYLFFFTEKILKILLKQKNEH---- 251
+A+ L P+ G + + +S + + G Y FF E + +LL + E
Sbjct: 375 DAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDG 434
Query: 252 ---HHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVG 308
H HSH GV +L +L P H S D A E
Sbjct: 435 PCGHSSHSHGG---------HSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPEL---- 481
Query: 309 SLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGIS 368
L+ + + S ++ L +MITL D +HNF DGLA+GA+F S G++
Sbjct: 482 -LNPEPRRLSP------------ELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLA 528
Query: 369 TSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG-SHFSANW 427
TS+A+ C E PHELGDF LL+AG+S++QAL N SA + GL + G S S W
Sbjct: 529 TSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAW 588
Query: 428 IFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMVVLTMYSG 487
I A+A G+FLY++L DM P M +V D R + F++ N+GLL G+T++++L++Y
Sbjct: 589 ILAVATGLFLYVALCDMLPAMLKV--RDPRPWLL---FLLHNVGLLGGWTVLLLLSLYED 643
Query: 488 QI 489
I
Sbjct: 644 DI 645
>gi|153252214 solute carrier family 39 (zinc transporter), member 6
isoform 2 [Homo sapiens]
Length = 433
Score = 189 bits (479), Expect = 6e-48
Identities = 130/432 (30%), Positives = 197/432 (45%), Gaps = 98/432 (22%)
Query: 106 QSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVIS 165
Q + ++E CP I+ Q+D+R+C +E+ + S W G + +++IS
Sbjct: 4 QVPLNATEFNYLCPAIINQIDARSCLIHT--SEKKAEIPPKTYSLQIAWVGGFIAISIIS 61
Query: 166 LCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEAFG------------- 212
SLLG +VP M + F+K LL + +ALA+GTL +A L+P +
Sbjct: 62 FLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAM 121
Query: 213 -------FNPLEDYYVSKSA---------VVFGGFYLFFFTEKILKILL-----KQKNEH 251
F+ L + +SA GG Y F E +L ++ K+KN+
Sbjct: 122 EMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQK 181
Query: 252 --HHGHSHYASESLPSKKDQEEGVMEKLQNGD-------LDHMIPQHCSSELDGKAPMVD 302
+ + L + Q EK+ D D P H S+ A + +
Sbjct: 182 KPENDDDVEIKKQLSKYESQLSTNEEKVDTDDRTEGYLRADSQEPSHFDSQQP--AVLEE 239
Query: 303 EKVIVGSLSVQDLQA--------------------------------------------- 317
E+V++ Q++
Sbjct: 240 EEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHH 299
Query: 318 --SQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILC 375
S S Y + ++ + + TLAWM+ + DGLHNF DGLAIGA+FT + G+STSVA+ C
Sbjct: 300 PHSHSQRYSREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFC 359
Query: 376 EEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFSAN---WIFALA 432
E PHELGDF +LL AGM+++QA+ +N LSA YLG+A GI G H++ N WIFAL
Sbjct: 360 HELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIG-HYAENVSMWIFALT 418
Query: 433 GGMFLYISLADM 444
G+F+Y++L DM
Sbjct: 419 AGLFMYVALVDM 430
>gi|223633937 solute carrier family 39 (zinc transporter), member 12
isoform 2 [Homo sapiens]
Length = 654
Score = 186 bits (471), Expect = 5e-47
Identities = 136/445 (30%), Positives = 216/445 (48%), Gaps = 96/445 (21%)
Query: 75 RGNVTQHVQGHRNLS----------------TCFSSGDLFTAHNFSEQSRIGSSELQEFC 118
+ N+ H Q + N S TCFS+ L S I + ++
Sbjct: 278 QNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMS 337
Query: 119 PTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFM 178
P I+QQL S +C + +Q + P+ +E +GY + VT+++L S+LG ++V F
Sbjct: 338 PGIIQQLLSCSC------HLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFH 391
Query: 179 K-KTFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLE-----DYYVSKSAV-----V 227
+ Y+ +L F+ LA+GTL +AL LIP+ G + E ++ SK + +
Sbjct: 392 SCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGL 451
Query: 228 FGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIP 287
GG + FF EK ILL N+ KK E+ ++
Sbjct: 452 IGGIHGFFLIEKCF-ILLVSPND---------------KKSPEDSQAAEMP--------- 486
Query: 288 QHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLH 347
+GS++ AS C I LA MI + D LH
Sbjct: 487 -------------------IGSMT-----ASNRKC--------KAISLLAIMILVGDSLH 514
Query: 348 NFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSAC 407
NF DGLAIGA+F+ S G++T++AILC E PHE+GDF +LL++G+S++ A+ NF+S+
Sbjct: 515 NFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSL 574
Query: 408 CCYLGLAFGI-LAGSHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFI 466
++GL G+ ++ +WIF + GMFLY+SL +M PEM V + +R + F+
Sbjct: 575 TAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHV--QTQRPWMM---FL 629
Query: 467 IQNLGLLTGFTIMVVLTMYSGQIQI 491
+QN GL+ G+ +++L +Y I+I
Sbjct: 630 LQNFGLILGWLSLLLLAIYEQNIKI 654
>gi|206597541 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 136 bits (342), Expect = 5e-32
Identities = 111/404 (27%), Positives = 172/404 (42%), Gaps = 43/404 (10%)
Query: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSA 150
C + L S + + + CP +L Q+DSR C + SA
Sbjct: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSA 217
Query: 151 VEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEA 210
L V ++SL S L ++ + + LL + ALA+GTL +AL L+P A
Sbjct: 218 --------LAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHA 269
Query: 211 -----FGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPS 265
G L + + V GG +L F E +L +L H G
Sbjct: 270 QEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLL------RHRGL---------- 313
Query: 266 KKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWL 325
+ K +N + ++ P++ S E G A
Sbjct: 314 ---RPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGH 370
Query: 326 KGVRYSDIG--TLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELG 383
+G + G + WM+ L DGLHN DGLAIGA+F+ G+ST++A+ C E PHELG
Sbjct: 371 QGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELG 430
Query: 384 DFVILLNAGMSIQQALFFNFLSACCCYLG--LAFGILAGSHFSANWIFALAGGMFLYISL 441
DF +LL +G+S ++ L + +S G L G+ G W+F + G+FLY++L
Sbjct: 431 DFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVAL 490
Query: 442 ADMFPEMNEVCQEDERKGSILIPFI-IQNLGLLTGFTIMVVLTM 484
DM P + + + P + +Q LGLL G +M+ +T+
Sbjct: 491 VDMLPALLRPPE------PLPTPHVLLQGLGLLLGGGLMLAITL 528
>gi|206597539 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 136 bits (342), Expect = 5e-32
Identities = 111/404 (27%), Positives = 172/404 (42%), Gaps = 43/404 (10%)
Query: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSA 150
C + L S + + + CP +L Q+DSR C + SA
Sbjct: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSA 217
Query: 151 VEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEA 210
L V ++SL S L ++ + + LL + ALA+GTL +AL L+P A
Sbjct: 218 --------LAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHA 269
Query: 211 -----FGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPS 265
G L + + V GG +L F E +L +L H G
Sbjct: 270 QEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLL------RHRGL---------- 313
Query: 266 KKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWL 325
+ K +N + ++ P++ S E G A
Sbjct: 314 ---RPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGH 370
Query: 326 KGVRYSDIG--TLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELG 383
+G + G + WM+ L DGLHN DGLAIGA+F+ G+ST++A+ C E PHELG
Sbjct: 371 QGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELG 430
Query: 384 DFVILLNAGMSIQQALFFNFLSACCCYLG--LAFGILAGSHFSANWIFALAGGMFLYISL 441
DF +LL +G+S ++ L + +S G L G+ G W+F + G+FLY++L
Sbjct: 431 DFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVAL 490
Query: 442 ADMFPEMNEVCQEDERKGSILIPFI-IQNLGLLTGFTIMVVLTM 484
DM P + + + P + +Q LGLL G +M+ +T+
Sbjct: 491 VDMLPALLRPPE------PLPTPHVLLQGLGLLLGGGLMLAITL 528
>gi|117553619 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 102 bits (253), Expect = 1e-21
Identities = 107/386 (27%), Positives = 160/386 (41%), Gaps = 66/386 (17%)
Query: 134 NQENEENEQTEEGRPS------AVEVWGYGLLCVTVISLCSLLGASVVPFMKKT-FYKRL 186
+ E+ E G P AV +W Y L +IS ++P + ++ L
Sbjct: 109 DHEHSHGGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSL 168
Query: 187 LLYFIALAIGTLYSNALFQLIPEAF------------------GFNPLEDYYVSKSAVVF 228
L ++ A G L +A LIP A G P+ +S V
Sbjct: 169 LQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPI----LSVGLWVL 224
Query: 229 GGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKD--QEEGVMEKLQNGDLDHMI 286
G F EK ++ + K + H HGH H S + S QE EK
Sbjct: 225 SGIVAFLVVEKFVRHV-KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQ--------- 274
Query: 287 PQHCSSELDGKAPMVDEKVIVGSLSVQDLQAS-QSACYWLKGVRYSDIGTLAWMITLSDG 345
SSE + K +K GS +D Q+A +G+ D+ ++ +D
Sbjct: 275 ----SSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGL---DLRVSGYLNLAADL 327
Query: 346 LHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLS 405
HNF DGLAIGASF GI T++ +L E PHE+GDF IL+ +G S +QA+ L+
Sbjct: 328 AHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLT 387
Query: 406 ACCCYLGLAFGIL-----AGSHFSA----NWIFALAGGMFLYISLADMFPEMNEVCQEDE 456
A G A +L GS + W+ G F+Y++ + PE+
Sbjct: 388 AVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPEL-------L 440
Query: 457 RKGSILIPFIIQNLGLLTGFTIMVVL 482
R+ S L +++ LGLL G +MV++
Sbjct: 441 REASPL-QSLLEVLGLLGGVIMMVLI 465
>gi|117553608 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 102 bits (253), Expect = 1e-21
Identities = 107/386 (27%), Positives = 160/386 (41%), Gaps = 66/386 (17%)
Query: 134 NQENEENEQTEEGRPS------AVEVWGYGLLCVTVISLCSLLGASVVPFMKKT-FYKRL 186
+ E+ E G P AV +W Y L +IS ++P + ++ L
Sbjct: 109 DHEHSHGGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSL 168
Query: 187 LLYFIALAIGTLYSNALFQLIPEAF------------------GFNPLEDYYVSKSAVVF 228
L ++ A G L +A LIP A G P+ +S V
Sbjct: 169 LQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPI----LSVGLWVL 224
Query: 229 GGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKD--QEEGVMEKLQNGDLDHMI 286
G F EK ++ + K + H HGH H S + S QE EK
Sbjct: 225 SGIVAFLVVEKFVRHV-KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQ--------- 274
Query: 287 PQHCSSELDGKAPMVDEKVIVGSLSVQDLQAS-QSACYWLKGVRYSDIGTLAWMITLSDG 345
SSE + K +K GS +D Q+A +G+ D+ ++ +D
Sbjct: 275 ----SSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGL---DLRVSGYLNLAADL 327
Query: 346 LHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLS 405
HNF DGLAIGASF GI T++ +L E PHE+GDF IL+ +G S +QA+ L+
Sbjct: 328 AHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLT 387
Query: 406 ACCCYLGLAFGIL-----AGSHFSA----NWIFALAGGMFLYISLADMFPEMNEVCQEDE 456
A G A +L GS + W+ G F+Y++ + PE+
Sbjct: 388 AVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPEL-------L 440
Query: 457 RKGSILIPFIIQNLGLLTGFTIMVVL 482
R+ S L +++ LGLL G +MV++
Sbjct: 441 REASPL-QSLLEVLGLLGGVIMMVLI 465
>gi|40255101 solute carrier family 39 (zinc transporter), member 13
isoform b [Homo sapiens]
Length = 364
Score = 84.0 bits (206), Expect = 3e-16
Identities = 98/385 (25%), Positives = 147/385 (38%), Gaps = 75/385 (19%)
Query: 119 PTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFM 178
P + + + AC +N+E+E G ++ W LL ++ L + V+P
Sbjct: 35 PALRSRGTATACRLDNKESESWGALLSGE--RLDTWICSLLGSLMVGLSGVFPLLVIPLE 92
Query: 179 KKTFYKR-----LLLYFIALAIGTLYSNALFQLIPEAF---------GFNPLEDYYVSKS 224
T + L ++ A+G L N L+PEA+ G
Sbjct: 93 MGTMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCSASPGGEGQSLQQQQQLG 152
Query: 225 AVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDH 284
V G F EK+ L SK EEG +
Sbjct: 153 LWVIAGILTFLALEKMF---------------------LDSK---EEGTSQ--------- 179
Query: 285 MIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSD 344
AP D +L+ A +A L V S I ++ L++
Sbjct: 180 -------------APNKDPTAAAAALNGGHCLAQPAAEPGLGAVVRS-IKVSGYLNLLAN 225
Query: 345 GLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFL 404
+ NF GLA+ ASF VS G+ T++AIL E PHE+GDF ILL AG A
Sbjct: 226 TIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLS 285
Query: 405 SACCCYLGLAFGILA----GSHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGS 460
+A LG F I G +A W+ G FLYI+L ++ P++ E +ED +
Sbjct: 286 TALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIALVNVLPDLLE--EEDPWRS- 342
Query: 461 ILIPFIIQNLGLLTGFTIMVVLTMY 485
+ Q L L G +MV+ +++
Sbjct: 343 -----LQQLLLLCAGIVVMVLFSLF 362
>gi|190014617 solute carrier family 39 (zinc transporter), member 13
isoform a [Homo sapiens]
Length = 371
Score = 80.5 bits (197), Expect = 3e-15
Identities = 98/392 (25%), Positives = 147/392 (37%), Gaps = 82/392 (20%)
Query: 119 PTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFM 178
P + + + AC +N+E+E G ++ W LL ++ L + V+P
Sbjct: 35 PALRSRGTATACRLDNKESESWGALLSGE--RLDTWICSLLGSLMVGLSGVFPLLVIPLE 92
Query: 179 KKTFYKR-----LLLYFIALAIGTLYSNALFQLIPEAF---------GFNPLEDYYVSKS 224
T + L ++ A+G L N L+PEA+ G
Sbjct: 93 MGTMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCSASPGGEGQSLQQQQQLG 152
Query: 225 AVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDH 284
V G F EK+ L SK EEG +
Sbjct: 153 LWVIAGILTFLALEKMF---------------------LDSK---EEGTSQ--------- 179
Query: 285 MIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSD 344
AP D +L+ A +A L V S I ++ L++
Sbjct: 180 -------------APNKDPTAAAAALNGGHCLAQPAAEPGLGAVVRS-IKVSGYLNLLAN 225
Query: 345 GLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFL 404
+ NF GLA+ ASF VS G+ T++AIL E PHE+GDF ILL AG A
Sbjct: 226 TIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLS 285
Query: 405 SACCCYLGLAFGILAGS-----------HFSANWIFALAGGMFLYISLADMFPEMNEVCQ 453
+A LG F I S +A W+ G FLYI+L ++ P++ E +
Sbjct: 286 TALGGLLGAGFAICTQSPKGVVGCSPAAEETAAWVLPFTSGGFLYIALVNVLPDLLE--E 343
Query: 454 EDERKGSILIPFIIQNLGLLTGFTIMVVLTMY 485
ED + + Q L L G +MV+ +++
Sbjct: 344 EDPWRS------LQQLLLLCAGIVVMVLFSLF 369
>gi|156415986 solute carrier family 39 (zinc transporter), member 2
[Homo sapiens]
Length = 309
Score = 40.0 bits (92), Expect = 0.005
Identities = 32/117 (27%), Positives = 55/117 (47%), Gaps = 9/117 (7%)
Query: 337 AWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQ 396
A ++ LS H+ +GLA+G TV+ + +A+L + G + L++ G S +
Sbjct: 165 ALVLLLSLSFHSVFEGLAVGLQPTVAA--TVQLCLAVLAHKGLVVFGVGMRLVHLGTSSR 222
Query: 397 QALFFNFLSACCCYLGLAFGIL-------AGSHFSANWIFALAGGMFLYISLADMFP 446
A+F L A LGLA G+ G + + +A G FLY++ ++ P
Sbjct: 223 WAVFSILLLALMSPLGLAVGLAVTGGDSEGGRGLAQAVLEGVAAGTFLYVTFLEILP 279
>gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo
sapiens]
Length = 342
Score = 38.1 bits (87), Expect = 0.018
Identities = 30/118 (25%), Positives = 52/118 (44%), Gaps = 9/118 (7%)
Query: 339 MITLSDGLHNFIDGLAIGASF-------TVSVFQGISTSVAILCEEFPHELGDFVILLNA 391
++ L+ +HN +GLA+G F + + + ++ I + FP L + L A
Sbjct: 196 LLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGA 255
Query: 392 GMSIQQALFFNFLSACCCYLGLAFGILAG--SHFSANWIFALAGGMFLYISLADMFPE 447
G S +A ++ LS L FG A + + A A G +Y+ + D+ PE
Sbjct: 256 GFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPE 313
>gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo
sapiens]
Length = 335
Score = 38.1 bits (87), Expect = 0.018
Identities = 30/118 (25%), Positives = 52/118 (44%), Gaps = 9/118 (7%)
Query: 339 MITLSDGLHNFIDGLAIGASF-------TVSVFQGISTSVAILCEEFPHELGDFVILLNA 391
++ L+ +HN +GLA+G F + + + ++ I + FP L + L A
Sbjct: 189 LLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGA 248
Query: 392 GMSIQQALFFNFLSACCCYLGLAFGILAG--SHFSANWIFALAGGMFLYISLADMFPE 447
G S +A ++ LS L FG A + + A A G +Y+ + D+ PE
Sbjct: 249 GFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPE 306
>gi|21361423 solute carrier family 39 (zinc transporter), member 1
[Homo sapiens]
Length = 324
Score = 35.0 bits (79), Expect = 0.16
Identities = 34/151 (22%), Positives = 69/151 (45%), Gaps = 12/151 (7%)
Query: 337 AWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQ 396
A ++ S LH+ +GLA+G + + + +A+L + + + LL + + Q
Sbjct: 180 ACVLVFSLALHSVFEGLAVGLQRDRA--RAMELCLALLLHKGILAVSLSLRLLQSHLRAQ 237
Query: 397 QALFFNFLSACCCYLGLAFGI-LAGS-----HFSANWIFALAGGMFLYISLADMFPEMNE 450
L +C LG+ G LA S + + + +A G FLYI+ ++ P+ E
Sbjct: 238 VVAGCGILFSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQ--E 295
Query: 451 VCQEDERKGSILIPFIIQNLGLLTGFTIMVV 481
+ ++R +++ ++ LLTG + +
Sbjct: 296 LASSEQRILKVIL--LLAGFALLTGLLFIQI 324
>gi|118918411 zinc finger protein 777 [Homo sapiens]
Length = 831
Score = 32.3 bits (72), Expect = 1.0
Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 9/66 (13%)
Query: 96 DLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACT------SENQENEENEQTEEGRPS 149
D+ N E+S GSSE E ++QQ R CT +E Q+ EE E+ E+ P
Sbjct: 414 DMQEPENTLEESTEGSSEFSELKQMLVQQ---RNCTEGIVIKTEEQDEEEEEEEEDELPQ 470
Query: 150 AVEVWG 155
++ G
Sbjct: 471 HLQSLG 476
>gi|189181750 human immunodeficiency virus type I enhancer binding
protein 3 b [Homo sapiens]
Length = 2405
Score = 32.0 bits (71), Expect = 1.3
Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 18/90 (20%)
Query: 75 RGNVTQHVQGHRNLSTCFSSG-------------DLFTAHNFSEQSRIGSSELQEFCPTI 121
+GN+T+H++ + C +G DLF + R GS ++E +
Sbjct: 1794 KGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQ----DSEGREGSEAVEEHQFSD 1849
Query: 122 LQQLDSRACTSENQ-ENEENEQTEEGRPSA 150
L+ DS + E++ E+EE Q E RPS+
Sbjct: 1850 LEDSDSDSDLDEDEDEDEEESQDELSRPSS 1879
>gi|116089331 human immunodeficiency virus type I enhancer binding
protein 3 [Homo sapiens]
Length = 2406
Score = 32.0 bits (71), Expect = 1.3
Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 18/90 (20%)
Query: 75 RGNVTQHVQGHRNLSTCFSSG-------------DLFTAHNFSEQSRIGSSELQEFCPTI 121
+GN+T+H++ + C +G DLF + R GS ++E +
Sbjct: 1794 KGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQ----DSEGREGSEAVEEHQFSD 1849
Query: 122 LQQLDSRACTSENQ-ENEENEQTEEGRPSA 150
L+ DS + E++ E+EE Q E RPS+
Sbjct: 1850 LEDSDSDSDLDEDEDEDEEESQDELSRPSS 1879
>gi|154689858 SMYD family member 5 [Homo sapiens]
Length = 418
Score = 31.2 bits (69), Expect = 2.2
Identities = 16/36 (44%), Positives = 19/36 (52%), Gaps = 2/36 (5%)
Query: 118 CPTILQQLDSRACTSENQENEENEQTEEGRPSAVEV 153
CP L + D TSE +E EE E EEG P E+
Sbjct: 378 CPKCLAEADEPNVTSEEEEEEEEE--EEGEPEDAEL 411
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,651,385
Number of Sequences: 37866
Number of extensions: 749799
Number of successful extensions: 2474
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2344
Number of HSP's gapped (non-prelim): 79
length of query: 492
length of database: 18,247,518
effective HSP length: 106
effective length of query: 386
effective length of database: 14,233,722
effective search space: 5494216692
effective search space used: 5494216692
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.