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Search of human proteins with 20149528
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20149528 proline-serine-threonine phosphatase interacting
protein 1 [Homo sapiens]
(416 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20149528 proline-serine-threonine phosphatase interacting pro... 832 0.0
gi|165905601 proline-serine-threonine phosphatase interacting pr... 292 4e-79
gi|226371723 FCH domain only 2 isoform a [Homo sapiens] 100 4e-21
gi|19224660 protein kinase C and casein kinase substrate in neur... 99 9e-21
gi|239049457 FCH domain only 1 isoform b [Homo sapiens] 95 1e-19
gi|29789054 FCH domain only 1 isoform b [Homo sapiens] 95 1e-19
gi|239049440 FCH domain only 1 isoform a [Homo sapiens] 95 1e-19
gi|24308229 protein kinase C and casein kinase substrate in neur... 94 2e-19
gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens] 92 1e-18
gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens] 92 1e-18
gi|41406078 growth arrest-specific 7 isoform b [Homo sapiens] 92 1e-18
gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens] 92 1e-18
gi|226371725 FCH domain only 2 isoform b [Homo sapiens] 81 2e-15
gi|239049540 FCH domain only 1 isoform c [Homo sapiens] 69 6e-12
gi|148747351 protein kinase C and casein kinase substrate in neu... 69 1e-11
gi|27544941 myosin IF [Homo sapiens] 60 3e-09
gi|38524622 formin binding protein 1 [Homo sapiens] 60 4e-09
gi|55956916 myosin IE [Homo sapiens] 59 8e-09
gi|78000171 sorbin and SH3 domain containing 1 isoform 7 [Homo s... 59 1e-08
gi|78000169 sorbin and SH3 domain containing 1 isoform 6 [Homo s... 59 1e-08
gi|7661700 sorbin and SH3 domain containing 1 isoform 2 [Homo sa... 59 1e-08
gi|78000160 sorbin and SH3 domain containing 1 isoform 1 [Homo s... 59 1e-08
gi|63055059 SH3 and PX domains 2B [Homo sapiens] 59 1e-08
gi|68348709 formin binding protein 1-like isoform 1 [Homo sapiens] 57 2e-08
gi|41581463 formin binding protein 1-like isoform 2 [Homo sapiens] 57 2e-08
gi|115298672 neutrophil cytosolic factor 1 [Homo sapiens] 57 3e-08
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 57 3e-08
gi|89886447 nitric oxide synthase trafficker isoform 2 [Homo sap... 56 5e-08
gi|78000167 sorbin and SH3 domain containing 1 isoform 5 [Homo s... 56 5e-08
gi|39930351 dynamin binding protein [Homo sapiens] 56 7e-08
>gi|20149528 proline-serine-threonine phosphatase interacting
protein 1 [Homo sapiens]
Length = 416
Score = 832 bits (2150), Expect = 0.0
Identities = 416/416 (100%), Positives = 416/416 (100%)
Query: 1 MMPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQI 60
MMPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQI
Sbjct: 1 MMPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQI 60
Query: 61 ARKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYE 120
ARKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYE
Sbjct: 61 ARKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYE 120
Query: 121 AVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQC 180
AVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQC
Sbjct: 121 AVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQC 180
Query: 181 KDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSM 240
KDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSM
Sbjct: 181 KDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSM 240
Query: 241 QCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNYYDREVTPLTSSPG 300
QCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNYYDREVTPLTSSPG
Sbjct: 241 QCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNYYDREVTPLTSSPG 300
Query: 301 IQPSCGMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERNEGVYTAIAVQEIQGNPASP 360
IQPSCGMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERNEGVYTAIAVQEIQGNPASP
Sbjct: 301 IQPSCGMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERNEGVYTAIAVQEIQGNPASP 360
Query: 361 AQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEKL 416
AQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEKL
Sbjct: 361 AQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEKL 416
>gi|165905601 proline-serine-threonine phosphatase interacting
protein 2 [Homo sapiens]
Length = 334
Score = 292 bits (747), Expect = 4e-79
Identities = 143/304 (47%), Positives = 199/304 (65%), Gaps = 1/304 (0%)
Query: 2 MPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIA 61
M + FK FW D + GY+ ++Q L +GRK CK+ E+ L++RA EERYGK+L+ ++
Sbjct: 1 MTRSLFKGNFWSADILSTIGYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLS 60
Query: 62 RKAG-GQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYE 120
RK GQ+EIN+L+ + + KQQ++NV HIQLA +LREE R +EEFRE+QK QRKK E
Sbjct: 61 RKKPCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTE 120
Query: 121 AVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQC 180
+MD + K K +KK M++KK YEQKCRD D+AEQA R + + KQ EK K
Sbjct: 121 LIMDAIHKQKSLQFKKTMDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATS 180
Query: 181 KDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSM 240
K + ++++ Y I L+KVR EW+ EH CEAF+ QE +R+ RNALW+H NQLS
Sbjct: 181 KTAVEDSDKAYMLHIGTLDKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQ 240
Query: 241 QCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNYYDREVTPLTSSPG 300
QCV DE+YE+VR +LE CSI DI+ F+ + TG PPAP+ Y+N+Y + + +
Sbjct: 241 QCVTSDEMYEQVRKSLEMCSIQRDIEYFVNQRKTGQIPPAPIMYENFYSSQKNAVPAGKA 300
Query: 301 IQPS 304
P+
Sbjct: 301 TGPN 304
>gi|226371723 FCH domain only 2 isoform a [Homo sapiens]
Length = 810
Score = 99.8 bits (247), Expect = 4e-21
Identities = 88/407 (21%), Positives = 181/407 (44%), Gaps = 46/407 (11%)
Query: 2 MPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIA 61
M F + FW ++G++VL + G+ K++ + +R+RA EE Y + + ++A
Sbjct: 1 MVMAYFVENFWGEK---NSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLA 57
Query: 62 RKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYE- 120
+ A +++ + +D K E + + H+ L L+E ++ ++++ E Q + KK +
Sbjct: 58 KSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKE 117
Query: 121 ---AVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANG-HQKQVEKSQNK 176
++ VQ + S+ + +SK+ Y KC EQ ER+ G Q+++EK+ K
Sbjct: 118 EVAGTLEAVQTIQ-SITQALQKSKENYNAKC-----VEQ--ERLKKEGATQREIEKAAVK 169
Query: 177 ARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSN 236
+++ D+ Y+ + + +A++EQ+ T + FQ E L ++ + SN
Sbjct: 170 SKKATDT-------YKLYVEKYALAKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSN 222
Query: 237 QLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNYYDREVTPLT 296
+ ++ +++EE + ++++ I F ++K TG E P + ++ E +
Sbjct: 223 AIKEIHLQIGQVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFE-----ECDTAS 277
Query: 297 SSPGIQPSCGMIKRFSGLLHGS--------PKTTSLAASAASTETLTPTPERNEG----- 343
+ GI+P G++ P SL E + PE N+
Sbjct: 278 AVEGIKPRKRKTFALPGIIKKEKDAESVECPDADSLNIPDVDEEGYSIKPETNQNDTKEN 337
Query: 344 -VYTAIAVQEIQGNPASPAQEYRALY----DYTAQNPDELDLSAGDI 385
Y++ P E + ++ +T + DEL +S G+I
Sbjct: 338 HFYSSSDSDSEDEEPKKYRIEIKPMHPNNSHHTMASLDELKVSIGNI 384
>gi|19224660 protein kinase C and casein kinase substrate in neurons
3 [Homo sapiens]
Length = 424
Score = 98.6 bits (244), Expect = 9e-21
Identities = 95/418 (22%), Positives = 171/418 (40%), Gaps = 44/418 (10%)
Query: 22 YEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARKAGGQTE----INSLRASF 77
Y +QR+ DG ++C D+ ++RA+ E+ Y ++L ARK G E +L ++
Sbjct: 22 YRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLADWARKWRGTVEKGPQYGTLEKAW 81
Query: 78 DSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYEAVMD------------- 124
+ E + + H+++ RE+L+ + R R ++ + V+
Sbjct: 82 HAFFTAAERLSALHLEV----REKLQGQDSERVRAWQRGAFHRPVLGGFRESRAAEDGFR 137
Query: 125 RVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANG--HQKQVEKSQNKARQCKD 182
+ QK L K+ SKK+Y +D A+ A+ Q+Q+ K Q + +C
Sbjct: 138 KAQKPWLKRLKEVEASKKSYHAARKDEKTAQTRESHAKADSAVSQEQLRKLQERVERCAK 197
Query: 183 SATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQC 242
A + + Y Q++A+L + + ++ E Q E RL ++ L L +
Sbjct: 198 EAEKTKAQYEQTLAELHRYTPRYMEDMEQAFETCQAAERQRLLFFKDMLLTLHQHLDLSS 257
Query: 243 V-KDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNYYDREVTPLTSSPGI 301
K EL+ ++ +E S + D+ + G P + D + T G
Sbjct: 258 SEKFHELHRDLHQGIEAASDEEDLRWWRSTHGPGMAMNWPQFEEWSLDTQRTISRKEKGG 317
Query: 302 QPSCGMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERNEGVYTAIAVQ---EIQGNPA 358
+ SP +L + + + P P+ T + E A
Sbjct: 318 R---------------SPDEVTLTSIVPTRDGTAPPPQSPGSPGTGQDEEWSDEESPRKA 362
Query: 359 SPAQEYRALYDYTAQNPDELDLSAG-DILEVILEGEDGWWTVE-RNGQRGFVPGSYLE 414
+ RALYDY Q DEL AG ++L++ E E GW + ++G+ G P +Y+E
Sbjct: 363 ATGVRVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPANYVE 420
>gi|239049457 FCH domain only 1 isoform b [Homo sapiens]
Length = 889
Score = 94.7 bits (234), Expect = 1e-19
Identities = 63/285 (22%), Positives = 140/285 (49%), Gaps = 21/285 (7%)
Query: 7 FKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARKAGG 66
F + FW + G+EVL + G K++ + +R+RA EE Y K + ++++ A
Sbjct: 4 FGEHFWGEK---NHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASN 60
Query: 67 QTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYE----AV 122
T + + ++ + + + H++L L++ ++ + + E Q + KK + +
Sbjct: 61 GTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVST 120
Query: 123 MDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQCKD 182
+D VQ + + +S++ Y +C D ++ R S + QK+++K++ K ++ +
Sbjct: 121 LDAVQVLS-GVSQLLPKSRENYLNRCMD----QERLRRESTS--QKEMDKAETKTKKAAE 173
Query: 183 SATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQC 242
S R+S+ + RA++EQ+ + FQ E L ++ L +++ +
Sbjct: 174 SL-------RRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTH 226
Query: 243 VKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNY 287
V+ +++EE + +E S++ + F ++K TG E P P+ ++ Y
Sbjct: 227 VQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAY 271
>gi|29789054 FCH domain only 1 isoform b [Homo sapiens]
Length = 889
Score = 94.7 bits (234), Expect = 1e-19
Identities = 63/285 (22%), Positives = 140/285 (49%), Gaps = 21/285 (7%)
Query: 7 FKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARKAGG 66
F + FW + G+EVL + G K++ + +R+RA EE Y K + ++++ A
Sbjct: 4 FGEHFWGEK---NHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASN 60
Query: 67 QTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYE----AV 122
T + + ++ + + + H++L L++ ++ + + E Q + KK + +
Sbjct: 61 GTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVST 120
Query: 123 MDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQCKD 182
+D VQ + + +S++ Y +C D ++ R S + QK+++K++ K ++ +
Sbjct: 121 LDAVQVLS-GVSQLLPKSRENYLNRCMD----QERLRRESTS--QKEMDKAETKTKKAAE 173
Query: 183 SATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQC 242
S R+S+ + RA++EQ+ + FQ E L ++ L +++ +
Sbjct: 174 SL-------RRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTH 226
Query: 243 VKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNY 287
V+ +++EE + +E S++ + F ++K TG E P P+ ++ Y
Sbjct: 227 VQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAY 271
>gi|239049440 FCH domain only 1 isoform a [Homo sapiens]
Length = 891
Score = 94.7 bits (234), Expect = 1e-19
Identities = 63/285 (22%), Positives = 140/285 (49%), Gaps = 21/285 (7%)
Query: 7 FKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARKAGG 66
F + FW + G+EVL + G K++ + +R+RA EE Y K + ++++ A
Sbjct: 4 FGEHFWGEK---NHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASN 60
Query: 67 QTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYE----AV 122
T + + ++ + + + H++L L++ ++ + + E Q + KK + +
Sbjct: 61 GTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVST 120
Query: 123 MDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQCKD 182
+D VQ + + +S++ Y +C D ++ R S + QK+++K++ K ++ +
Sbjct: 121 LDAVQVLS-GVSQLLPKSRENYLNRCMD----QERLRRESTS--QKEMDKAETKTKKAAE 173
Query: 183 SATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQC 242
S R+S+ + RA++EQ+ + FQ E L ++ L +++ +
Sbjct: 174 SL-------RRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTH 226
Query: 243 VKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNY 287
V+ +++EE + +E S++ + F ++K TG E P P+ ++ Y
Sbjct: 227 VQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAY 271
>gi|24308229 protein kinase C and casein kinase substrate in neurons
1 [Homo sapiens]
Length = 444
Score = 94.4 bits (233), Expect = 2e-19
Identities = 102/447 (22%), Positives = 186/447 (41%), Gaps = 58/447 (12%)
Query: 9 DAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARKAGGQT 68
D+FW Y+ ++R+ DG ++C D+ +++RA+ E+ YG++L A++
Sbjct: 17 DSFW-----EVGNYKRTVKRIDDGHRLCNDLMNCVQERAKIEKAYGQQLTDWAKRWRQLI 71
Query: 69 E----INSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKE---------- 114
E SL ++ ++ + + V H ++ L E LE+ + QK+
Sbjct: 72 EKGPQYGSLERAWGAIMTEADKVSELHQEVKNNLLNE--DLEKVKNWQKDAYHKQIMGGF 129
Query: 115 -QRKKYEAVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDA--EQAFERISANGHQKQVE 171
+ K+ E + QK K+ +KK Y C++ A + + + +Q +
Sbjct: 130 KETKEAEDGFRKAQKPWAKKMKELEAAKKAYHLACKEEKLAMTREMNSKTEQSVTPEQQK 189
Query: 172 KSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNAL 231
K Q+K +CK + + Y + + + K ++ + E Q E RL L+ L
Sbjct: 190 KLQDKVDKCKQDVQKTQEKYEKVLEDVGKTTPQYMENMEQVFEQCQQFEEKRLVFLKEVL 249
Query: 232 WVHSNQLSM-QCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNYYDR 290
L++ + +Y E+ + G D+ F ++G P P ++
Sbjct: 250 LDIKRHLNLAENSSYIHVYRELEQAIRGADAQEDLRWF--RSTSGPGMPMNWPQFEEWNP 307
Query: 291 EVTPLTSSPGIQPSCGMIKRFSGL----LHGSPKTTSLAASAASTETLTPTPERNEGVYT 346
++ T+ QP K+ G+ G+ ++TS A S + +R + T
Sbjct: 308 DLPHTTTKKEKQP-----KKAEGVALTNATGAVESTSQAGDRGSVSSY----DRGQPYAT 358
Query: 347 AIAVQEIQGNP---------ASPAQE------YRALYDYTAQNPDELDLSAGDILEVILE 391
+ E GNP A+P ++ RALYDY Q DEL AGD L + E
Sbjct: 359 EWSDDE-SGNPFGGSETNGGANPFEDDSKGVRVRALYDYDGQEQDELSFKAGDELTKLGE 417
Query: 392 GEDGWWTVER--NGQRGFVPGSYLEKL 416
++ W R +GQ G P +Y+E +
Sbjct: 418 EDEQGWCRGRLDSGQLGLYPANYVEAI 444
>gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens]
Length = 412
Score = 91.7 bits (226), Expect = 1e-18
Identities = 62/260 (23%), Positives = 125/260 (48%), Gaps = 8/260 (3%)
Query: 21 GYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARKAGGQTEINSLRASFDSL 80
G+E+LLQ+ L G++M K+M E +R+R + EE Y K L ++++ + E SL ++ +
Sbjct: 155 GFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQV 214
Query: 81 KQQMENVGSSHIQLALTLREEL-RSLEEFRERQKEQRKKYEAVMDRVQKSKLSLYKKAME 139
K+ + + H++ + L E+ + L FRE K+ KK + + ++K S Y +
Sbjct: 215 KKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEK 274
Query: 140 SKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLE 199
++K ++ RD + Q E +N ++ ++K++ K+ Q D +Y Q+
Sbjct: 275 ARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQA----- 329
Query: 200 KVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGC 259
+++W +E TT + E +R+ ++R L ++ + + E V L
Sbjct: 330 --QSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKV 387
Query: 260 SIDADIDSFIQAKSTGTEPP 279
D + +++ TG P
Sbjct: 388 DPAKDRELWVREHKTGNIRP 407
>gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens]
Length = 476
Score = 91.7 bits (226), Expect = 1e-18
Identities = 62/260 (23%), Positives = 125/260 (48%), Gaps = 8/260 (3%)
Query: 21 GYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARKAGGQTEINSLRASFDSL 80
G+E+LLQ+ L G++M K+M E +R+R + EE Y K L ++++ + E SL ++ +
Sbjct: 219 GFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQV 278
Query: 81 KQQMENVGSSHIQLALTLREEL-RSLEEFRERQKEQRKKYEAVMDRVQKSKLSLYKKAME 139
K+ + + H++ + L E+ + L FRE K+ KK + + ++K S Y +
Sbjct: 279 KKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEK 338
Query: 140 SKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLE 199
++K ++ RD + Q E +N ++ ++K++ K+ Q D +Y Q+
Sbjct: 339 ARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQA----- 393
Query: 200 KVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGC 259
+++W +E TT + E +R+ ++R L ++ + + E V L
Sbjct: 394 --QSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKV 451
Query: 260 SIDADIDSFIQAKSTGTEPP 279
D + +++ TG P
Sbjct: 452 DPAKDRELWVREHKTGNIRP 471
Score = 36.2 bits (82), Expect = 0.056
Identities = 17/54 (31%), Positives = 33/54 (61%), Gaps = 2/54 (3%)
Query: 365 RALYDYTAQNPDE-LDLSAGDILEVILEGEDGWWTVER-NGQRGFVPGSYLEKL 416
R LY ++ + + L +AG+++ ++ + GWW E+ +G RG+ P SY++ L
Sbjct: 7 RTLYPFSGERHGQGLRFAAGELITLLQVPDGGWWEGEKEDGLRGWFPASYVQLL 60
>gi|41406078 growth arrest-specific 7 isoform b [Homo sapiens]
Length = 416
Score = 91.7 bits (226), Expect = 1e-18
Identities = 62/260 (23%), Positives = 125/260 (48%), Gaps = 8/260 (3%)
Query: 21 GYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARKAGGQTEINSLRASFDSL 80
G+E+LLQ+ L G++M K+M E +R+R + EE Y K L ++++ + E SL ++ +
Sbjct: 159 GFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQV 218
Query: 81 KQQMENVGSSHIQLALTLREEL-RSLEEFRERQKEQRKKYEAVMDRVQKSKLSLYKKAME 139
K+ + + H++ + L E+ + L FRE K+ KK + + ++K S Y +
Sbjct: 219 KKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEK 278
Query: 140 SKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLE 199
++K ++ RD + Q E +N ++ ++K++ K+ Q D +Y Q+
Sbjct: 279 ARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQA----- 333
Query: 200 KVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGC 259
+++W +E TT + E +R+ ++R L ++ + + E V L
Sbjct: 334 --QSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKV 391
Query: 260 SIDADIDSFIQAKSTGTEPP 279
D + +++ TG P
Sbjct: 392 DPAKDRELWVREHKTGNIRP 411
>gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens]
Length = 336
Score = 91.7 bits (226), Expect = 1e-18
Identities = 62/260 (23%), Positives = 125/260 (48%), Gaps = 8/260 (3%)
Query: 21 GYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARKAGGQTEINSLRASFDSL 80
G+E+LLQ+ L G++M K+M E +R+R + EE Y K L ++++ + E SL ++ +
Sbjct: 79 GFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQV 138
Query: 81 KQQMENVGSSHIQLALTLREEL-RSLEEFRERQKEQRKKYEAVMDRVQKSKLSLYKKAME 139
K+ + + H++ + L E+ + L FRE K+ KK + + ++K S Y +
Sbjct: 139 KKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEK 198
Query: 140 SKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLE 199
++K ++ RD + Q E +N ++ ++K++ K+ Q D +Y Q+
Sbjct: 199 ARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQA----- 253
Query: 200 KVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGC 259
+++W +E TT + E +R+ ++R L ++ + + E V L
Sbjct: 254 --QSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKV 311
Query: 260 SIDADIDSFIQAKSTGTEPP 279
D + +++ TG P
Sbjct: 312 DPAKDRELWVREHKTGNIRP 331
>gi|226371725 FCH domain only 2 isoform b [Homo sapiens]
Length = 777
Score = 80.9 bits (198), Expect = 2e-15
Identities = 82/407 (20%), Positives = 168/407 (41%), Gaps = 79/407 (19%)
Query: 2 MPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIA 61
M F + FW ++G++VL + G+ K++ + +R+RA EE Y + + ++A
Sbjct: 1 MVMAYFVENFWGEK---NSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLA 57
Query: 62 RKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYE- 120
+ A +++ + +D K E + + H+ L L+E ++ ++++ E Q + KK +
Sbjct: 58 KSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKE 117
Query: 121 ---AVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANG-HQKQVEKSQNK 176
++ VQ + S+ + +SK+ Y KC EQ ER+ G Q+++EK+ K
Sbjct: 118 EVAGTLEAVQTIQ-SITQALQKSKENYNAKC-----VEQ--ERLKKEGATQREIEKAAVK 169
Query: 177 ARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSN 236
+++ D+ Y+ + + +A++EQ+ T
Sbjct: 170 SKKATDT-------YKLYVEKYALAKADFEQKMTETA----------------------- 199
Query: 237 QLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNYYDREVTPLT 296
+++EE + ++++ I F ++K TG E P + ++ E +
Sbjct: 200 ----------QVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFE-----ECDTAS 244
Query: 297 SSPGIQPSCGMIKRFSGLLHGS--------PKTTSLAASAASTETLTPTPERNEG----- 343
+ GI+P G++ P SL E + PE N+
Sbjct: 245 AVEGIKPRKRKTFALPGIIKKEKDAESVECPDADSLNIPDVDEEGYSIKPETNQNDTKEN 304
Query: 344 -VYTAIAVQEIQGNPASPAQEYRALY----DYTAQNPDELDLSAGDI 385
Y++ P E + ++ +T + DEL +S G+I
Sbjct: 305 HFYSSSDSDSEDEEPKKYRIEIKPMHPNNSHHTMASLDELKVSIGNI 351
>gi|239049540 FCH domain only 1 isoform c [Homo sapiens]
Length = 839
Score = 69.3 bits (168), Expect = 6e-12
Identities = 47/235 (20%), Positives = 115/235 (48%), Gaps = 18/235 (7%)
Query: 57 LVQIARKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQR 116
+ ++++ A T + + ++ + + + H++L L++ ++ + + E Q +
Sbjct: 1 MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTH 60
Query: 117 KKYE----AVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANGHQKQVEK 172
KK + + +D VQ + + +S++ Y +C D ++ R S + QK+++K
Sbjct: 61 KKCKEEVVSTLDAVQVLS-GVSQLLPKSRENYLNRCMD----QERLRRESTS--QKEMDK 113
Query: 173 SQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALW 232
++ K ++ +S R+S+ + RA++EQ+ + FQ E L ++ L
Sbjct: 114 AETKTKKAAESL-------RRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLG 166
Query: 233 VHSNQLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNY 287
+++ + V+ +++EE + +E S++ + F ++K TG E P P+ ++ Y
Sbjct: 167 SYAHSVEDTHVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAY 221
>gi|148747351 protein kinase C and casein kinase substrate in
neurons 2 [Homo sapiens]
Length = 486
Score = 68.6 bits (166), Expect = 1e-11
Identities = 57/278 (20%), Positives = 119/278 (42%), Gaps = 25/278 (8%)
Query: 9 DAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARKAGGQT 68
D+FW Y+ ++R+ DG ++C D+ L +RA+ E+ Y ++L + AR+
Sbjct: 16 DSFW-----EVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLV 70
Query: 69 E----INSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKE---------- 114
E ++ ++ + + E V H+++ +L + E+ + QKE
Sbjct: 71 EKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMND--DFEKIKNWQKEAFHKQMMGGF 128
Query: 115 -QRKKYEAVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDA--EQAFERISANGHQKQVE 171
+ K+ E + QK K+ +KK + C++ A +A + + + +Q++
Sbjct: 129 KETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLK 188
Query: 172 KSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNAL 231
K Q+K +CK + + Y +S+ +L++ ++ + E Q E RL R L
Sbjct: 189 KLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVL 248
Query: 232 WVHSNQLSMQCVKD-DELYEEVRLTLEGCSIDADIDSF 268
L + V +Y ++ ++ D+ F
Sbjct: 249 LEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWF 286
>gi|27544941 myosin IF [Homo sapiens]
Length = 1098
Score = 60.5 bits (145), Expect = 3e-09
Identities = 26/78 (33%), Positives = 42/78 (53%)
Query: 339 ERNEGVYTAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWT 398
+R+ G V + P + RALY Y Q+ DEL + +++E+++E GWW
Sbjct: 1021 KRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSGWWK 1080
Query: 399 VERNGQRGFVPGSYLEKL 416
+GQ G PG+Y+EK+
Sbjct: 1081 GRLHGQEGLFPGNYVEKI 1098
>gi|38524622 formin binding protein 1 [Homo sapiens]
Length = 617
Score = 60.1 bits (144), Expect = 4e-09
Identities = 57/265 (21%), Positives = 118/265 (44%), Gaps = 25/265 (9%)
Query: 41 ELLRQRAQAEERYGKELVQIARK--------AGGQTEINSLRASFDSLKQQMENVGSSHI 92
+ +++R + E Y K+L +++K + + S +A +L + + G +
Sbjct: 30 KFVKERTEIELSYAKQLRNLSKKYQPKKNSKEEEEYKYTSCKAFISNLNEMNDYAGQHEV 89
Query: 93 QLALTLREELRSLEEFRERQKEQRKKYEAVMDRVQKSKLSLYKKAMESKKTYEQKCRDAD 152
+ + L + + K++RK + Q+ + +K+ SK+ +E+ C++AD
Sbjct: 90 ISENMASQIIVDLARYVQELKQERKSNFHDGRKAQQHIETCWKQLESSKRRFERDCKEAD 149
Query: 153 DAEQAFERISA--NGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHR 210
A+Q FE++ A N + VEK++ +A+ A +++ Y + + + E+ H
Sbjct: 150 RAQQYFEKMDADINVTKADVEKARQQAQIRHQMAEDSKADYSSILQKFNHEQHEYYHTH- 208
Query: 211 TTCEAFQ-LQEFDRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGC-----SIDAD 264
FQ +QE + I+R + D ++ + L+G SID
Sbjct: 209 -IPNIFQKIQEMEERRIVR-----MGESMKTYAEVDRQVIPIIGKCLDGIVKAAESIDQK 262
Query: 265 IDS--FIQAKSTGTEPPAPVPYQNY 287
DS I+A +G EPP + +++Y
Sbjct: 263 NDSQLVIEAYKSGFEPPGDIEFEDY 287
Score = 39.7 bits (91), Expect = 0.005
Identities = 21/52 (40%), Positives = 31/52 (59%), Gaps = 2/52 (3%)
Query: 365 RALYDYTAQNPDELDLSAGDILEVILEGE-DGWWTVERN-GQRGFVPGSYLE 414
+ALY + QN + + G+ L VI E + DGW + RN + G+VP SY+E
Sbjct: 556 KALYTFEGQNEGTISVVEGETLYVIEEDKGDGWTRIRRNEDEEGYVPTSYVE 607
>gi|55956916 myosin IE [Homo sapiens]
Length = 1108
Score = 58.9 bits (141), Expect = 8e-09
Identities = 25/63 (39%), Positives = 37/63 (58%)
Query: 354 QGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYL 413
Q P + +ALY Y AQ+ DEL +A DI+++I E GWWT G++G P +Y+
Sbjct: 1046 QPKPKPQVPQCKALYAYDAQDTDELSFNANDIIDIIKEDPSGWWTGRLRGKQGLFPNNYV 1105
Query: 414 EKL 416
K+
Sbjct: 1106 TKI 1108
>gi|78000171 sorbin and SH3 domain containing 1 isoform 7 [Homo
sapiens]
Length = 740
Score = 58.5 bits (140), Expect = 1e-08
Identities = 43/136 (31%), Positives = 70/136 (51%), Gaps = 9/136 (6%)
Query: 285 QNYYDREVTPLTSSPGIQPSC--GMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERNE 342
+N+Y+ + P TS GI P +IKR L+ L S++ + + T +P++ +
Sbjct: 608 ENWYEGRI-PGTSRQGIFPITYVDVIKR--PLVKNPVDYMDLPFSSSPSRSATASPQQPQ 664
Query: 343 GVYTAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWW--TVE 400
+ Q + Y+ALY Y QN DEL+L GDI++V+ + +DGW+ T
Sbjct: 665 AQQRRVTPDRSQ--TSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSR 722
Query: 401 RNGQRGFVPGSYLEKL 416
R Q G PG+Y++ L
Sbjct: 723 RTKQFGTFPGNYVKPL 738
Score = 41.6 bits (96), Expect = 0.001
Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 3/62 (4%)
Query: 355 GNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLE 414
G+ PA RA +D+ AQ EL L GDI+ + + + W+ E +G+ G P +Y+E
Sbjct: 498 GSEMRPA---RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIE 554
Query: 415 KL 416
L
Sbjct: 555 LL 556
>gi|78000169 sorbin and SH3 domain containing 1 isoform 6 [Homo
sapiens]
Length = 781
Score = 58.5 bits (140), Expect = 1e-08
Identities = 43/136 (31%), Positives = 70/136 (51%), Gaps = 9/136 (6%)
Query: 285 QNYYDREVTPLTSSPGIQPSC--GMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERNE 342
+N+Y+ + P TS GI P +IKR L+ L S++ + + T +P++ +
Sbjct: 649 ENWYEGRI-PGTSRQGIFPITYVDVIKR--PLVKNPVDYMDLPFSSSPSRSATASPQQPQ 705
Query: 343 GVYTAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWW--TVE 400
+ Q + Y+ALY Y QN DEL+L GDI++V+ + +DGW+ T
Sbjct: 706 AQQRRVTPDRSQ--TSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSR 763
Query: 401 RNGQRGFVPGSYLEKL 416
R Q G PG+Y++ L
Sbjct: 764 RTKQFGTFPGNYVKPL 779
Score = 41.6 bits (96), Expect = 0.001
Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 3/62 (4%)
Query: 355 GNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLE 414
G+ PA RA +D+ AQ EL L GDI+ + + + W+ E +G+ G P +Y+E
Sbjct: 539 GSEMRPA---RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIE 595
Query: 415 KL 416
L
Sbjct: 596 LL 597
>gi|7661700 sorbin and SH3 domain containing 1 isoform 2 [Homo
sapiens]
Length = 816
Score = 58.5 bits (140), Expect = 1e-08
Identities = 43/136 (31%), Positives = 70/136 (51%), Gaps = 9/136 (6%)
Query: 285 QNYYDREVTPLTSSPGIQPSC--GMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERNE 342
+N+Y+ + P TS GI P +IKR L+ L S++ + + T +P++ +
Sbjct: 684 ENWYEGRI-PGTSRQGIFPITYVDVIKR--PLVKNPVDYMDLPFSSSPSRSATASPQQPQ 740
Query: 343 GVYTAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWW--TVE 400
+ Q + Y+ALY Y QN DEL+L GDI++V+ + +DGW+ T
Sbjct: 741 AQQRRVTPDRSQ--TSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSR 798
Query: 401 RNGQRGFVPGSYLEKL 416
R Q G PG+Y++ L
Sbjct: 799 RTKQFGTFPGNYVKPL 814
Score = 41.2 bits (95), Expect = 0.002
Identities = 19/52 (36%), Positives = 30/52 (57%)
Query: 365 RALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEKL 416
RA +D+ AQ EL L GDI+ + + + W+ E +G+ G P +Y+E L
Sbjct: 581 RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELL 632
>gi|78000160 sorbin and SH3 domain containing 1 isoform 1 [Homo
sapiens]
Length = 684
Score = 58.5 bits (140), Expect = 1e-08
Identities = 43/136 (31%), Positives = 70/136 (51%), Gaps = 9/136 (6%)
Query: 285 QNYYDREVTPLTSSPGIQPSC--GMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERNE 342
+N+Y+ + P TS GI P +IKR L+ L S++ + + T +P++ +
Sbjct: 552 ENWYEGRI-PGTSRQGIFPITYVDVIKR--PLVKNPVDYMDLPFSSSPSRSATASPQQPQ 608
Query: 343 GVYTAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWW--TVE 400
+ Q + Y+ALY Y QN DEL+L GDI++V+ + +DGW+ T
Sbjct: 609 AQQRRVTPDRSQ--TSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSR 666
Query: 401 RNGQRGFVPGSYLEKL 416
R Q G PG+Y++ L
Sbjct: 667 RTKQFGTFPGNYVKPL 682
Score = 41.2 bits (95), Expect = 0.002
Identities = 19/52 (36%), Positives = 30/52 (57%)
Query: 365 RALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEKL 416
RA +D+ AQ EL L GDI+ + + + W+ E +G+ G P +Y+E L
Sbjct: 449 RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELL 500
>gi|63055059 SH3 and PX domains 2B [Homo sapiens]
Length = 911
Score = 58.5 bits (140), Expect = 1e-08
Identities = 22/54 (40%), Positives = 37/54 (68%)
Query: 362 QEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEK 415
++Y +Y YTA++ DE++L G ++EVI + +GWW + G+ G+ P SYL+K
Sbjct: 224 EKYTVIYPYTARDQDEMNLERGAVVEVIQKNLEGWWKIRYQGKEGWAPASYLKK 277
Score = 46.2 bits (108), Expect = 5e-05
Identities = 18/53 (33%), Positives = 32/53 (60%)
Query: 362 QEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLE 414
++Y + +Y Q E+ LS G ++++I + E GWW V ++G+VP + LE
Sbjct: 155 EQYVVVANYQKQESSEISLSVGQVVDIIEKNESGWWFVSTAEEQGWVPATCLE 207
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/175 (19%), Positives = 63/175 (36%), Gaps = 21/175 (12%)
Query: 261 IDADIDSFIQAKSTGTEPPAPVPYQNYYDREVTPLTSSPGIQPSCGMI------------ 308
I +++ + + + G E AP Y E P PG G +
Sbjct: 251 IQKNLEGWWKIRYQGKEGWAPASYLKKNSGEPLPPKPGPGSPSHPGALDLDGVSRQQNAV 310
Query: 309 --------KRFSGLLHGSPKTTSLAASAASTETLTPTPERNEGVYTAIAVQEIQGNPASP 360
+ G G P A + P P R+ + + + + P
Sbjct: 311 GREKELLSSQRDGRFEGRPVPDGDAKQRSPKMRQRPPPRRDMTIPRGLNLPK-PPIPPQV 369
Query: 361 AQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEK 415
+EY + ++ PD + AG +EVI + GWW ++ + G+ P ++++K
Sbjct: 370 EEEYYTIAEFQTTIPDGISFQAGLKVEVIEKNLSGWWYIQIEDKEGWAPATFIDK 424
>gi|68348709 formin binding protein 1-like isoform 1 [Homo sapiens]
Length = 551
Score = 57.4 bits (137), Expect = 2e-08
Identities = 56/260 (21%), Positives = 106/260 (40%), Gaps = 16/260 (6%)
Query: 41 ELLRQRAQAEERYGKELVQIARK-------AGGQTEINSLRASFDSLKQQMENVGSSHIQ 93
+ +++R + E+ Y K+L + +K + S A F+ L + + G +
Sbjct: 30 KFVKERIEIEQNYAKQLRNLVKKYCPKRSSKDEEPRFTSCVAFFNILNELNDYAGQREVV 89
Query: 94 LALTLREELRSLEEFRERQKEQRKKYEAVMDRVQKSKLSLYKKAMESKKTYEQKCRDADD 153
L + K +RK + + Q+ +K+ SKK +E++CR+A+
Sbjct: 90 AEEMAHRVYGELMRYAHDLKTERKMHLQEGRKAQQYLDMCWKQMDNSKKKFERECREAEK 149
Query: 154 AEQAFERI--SANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRT 211
A+Q++ER+ N + VEK++ + A E + Y AQL+ E +
Sbjct: 150 AQQSYERLDNDTNATKADVEKAKQQLNLRTHMADENKNEY---AAQLQNFNGEQHKHFYV 206
Query: 212 TCEAF--QLQEFD-RLTILRNALWVHSNQLSMQCVK-DDELYEEVRLTLEGCSIDADIDS 267
QLQE D R TI + + + + + E + L + D
Sbjct: 207 VIPQIYKQLQEMDERRTIKLSECYRGFADSERKVIPIISKCLEGMILAAKSVDERRDSQM 266
Query: 268 FIQAKSTGTEPPAPVPYQNY 287
+ + +G EPP P+++Y
Sbjct: 267 VVDSFKSGFEPPGDFPFEDY 286
Score = 44.7 bits (104), Expect = 2e-04
Identities = 32/101 (31%), Positives = 48/101 (47%), Gaps = 20/101 (19%)
Query: 334 LTPTPERNEGVYTAIAVQEIQGNPAS-----------------PAQEY-RALYDYTAQNP 375
+T E EG YT A QE++G P PA + +A+Y + N
Sbjct: 437 VTQGRESPEGSYTDDANQEVRGPPQQHGHHNEFDDEFEDDDPLPAIGHCKAIYPFDGHNE 496
Query: 376 DELDLSAGDILEVILEGE-DGWWTVER-NGQRGFVPGSYLE 414
L + G++L +I E + DGW R NG+ G+VP SY++
Sbjct: 497 GTLAMKEGEVLYIIEEDKGDGWTRARRQNGEEGYVPTSYID 537
>gi|41581463 formin binding protein 1-like isoform 2 [Homo sapiens]
Length = 547
Score = 57.4 bits (137), Expect = 2e-08
Identities = 56/260 (21%), Positives = 106/260 (40%), Gaps = 16/260 (6%)
Query: 41 ELLRQRAQAEERYGKELVQIARK-------AGGQTEINSLRASFDSLKQQMENVGSSHIQ 93
+ +++R + E+ Y K+L + +K + S A F+ L + + G +
Sbjct: 30 KFVKERIEIEQNYAKQLRNLVKKYCPKRSSKDEEPRFTSCVAFFNILNELNDYAGQREVV 89
Query: 94 LALTLREELRSLEEFRERQKEQRKKYEAVMDRVQKSKLSLYKKAMESKKTYEQKCRDADD 153
L + K +RK + + Q+ +K+ SKK +E++CR+A+
Sbjct: 90 AEEMAHRVYGELMRYAHDLKTERKMHLQEGRKAQQYLDMCWKQMDNSKKKFERECREAEK 149
Query: 154 AEQAFERI--SANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRT 211
A+Q++ER+ N + VEK++ + A E + Y AQL+ E +
Sbjct: 150 AQQSYERLDNDTNATKADVEKAKQQLNLRTHMADENKNEY---AAQLQNFNGEQHKHFYV 206
Query: 212 TCEAF--QLQEFD-RLTILRNALWVHSNQLSMQCVK-DDELYEEVRLTLEGCSIDADIDS 267
QLQE D R TI + + + + + E + L + D
Sbjct: 207 VIPQIYKQLQEMDERRTIKLSECYRGFADSERKVIPIISKCLEGMILAAKSVDERRDSQM 266
Query: 268 FIQAKSTGTEPPAPVPYQNY 287
+ + +G EPP P+++Y
Sbjct: 267 VVDSFKSGFEPPGDFPFEDY 286
Score = 44.7 bits (104), Expect = 2e-04
Identities = 32/101 (31%), Positives = 48/101 (47%), Gaps = 20/101 (19%)
Query: 334 LTPTPERNEGVYTAIAVQEIQGNPAS-----------------PAQEY-RALYDYTAQNP 375
+T E EG YT A QE++G P PA + +A+Y + N
Sbjct: 437 VTQGRESPEGSYTDDANQEVRGPPQQHGHHNEFDDEFEDDDPLPAIGHCKAIYPFDGHNE 496
Query: 376 DELDLSAGDILEVILEGE-DGWWTVER-NGQRGFVPGSYLE 414
L + G++L +I E + DGW R NG+ G+VP SY++
Sbjct: 497 GTLAMKEGEVLYIIEEDKGDGWTRARRQNGEEGYVPTSYID 537
>gi|115298672 neutrophil cytosolic factor 1 [Homo sapiens]
Length = 390
Score = 57.0 bits (136), Expect = 3e-08
Identities = 23/55 (41%), Positives = 36/55 (65%)
Query: 362 QEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEKL 416
Q YRA+ +Y + E+ LS GD++EV+ + E GWW + +RG++P S+LE L
Sbjct: 159 QTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPL 213
Score = 48.5 bits (114), Expect = 1e-05
Identities = 22/59 (37%), Positives = 33/59 (55%)
Query: 357 PASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEK 415
P + Y A+ YTA DE+ L G+ +EVI + DGWW + ++ G+ P YL+K
Sbjct: 224 PNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQK 282
>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
sapiens]
Length = 756
Score = 57.0 bits (136), Expect = 3e-08
Identities = 27/66 (40%), Positives = 42/66 (63%), Gaps = 3/66 (4%)
Query: 354 QGNPAS---PAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPG 410
+G+PA P + + + Y+ + DEL L AG+I+E+I E EDGWW ++NGQ G P
Sbjct: 75 RGHPAKHPRPQRWCKVNFSYSPEQADELKLQAGEIVEMIKEIEDGWWLGKKNGQLGAFPS 134
Query: 411 SYLEKL 416
+++E L
Sbjct: 135 NFVELL 140
Score = 48.5 bits (114), Expect = 1e-05
Identities = 22/57 (38%), Positives = 35/57 (61%), Gaps = 2/57 (3%)
Query: 359 SPAQEYRALYDYTAQNPDELDLSAGDILEVILE--GEDGWWTVERNGQRGFVPGSYL 413
S + YR L+DY + PDEL L GD+++V+ + + GWW E G+RG P +++
Sbjct: 181 SHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFV 237
Score = 30.0 bits (66), Expect = 4.0
Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Query: 363 EYRALYDYTAQNPDELDLSAGDIL-EVILEGEDGWWTVERNGQRGFVPGSYLEKL 416
E L Y AQ DEL L+ GD++ +V GW E G+ G P ++++
Sbjct: 2 EVLVLAGYRAQKEDELSLAPGDVVRQVRWVPARGWLRGEFGGRYGLFPERLVQEI 56
Score = 29.3 bits (64), Expect = 6.9
Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 8/63 (12%)
Query: 69 EINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYEA-VMDRVQ 127
++ SLR +SL++ +E + + L +L + E + +KEQR++ E VM Q
Sbjct: 689 DVTSLRGEVESLRRALE-------LMEVQLERKLTDIWEELKSEKEQRRRLEVQVMQGTQ 741
Query: 128 KSK 130
KS+
Sbjct: 742 KSQ 744
>gi|89886447 nitric oxide synthase trafficker isoform 2 [Homo
sapiens]
Length = 506
Score = 56.2 bits (134), Expect = 5e-08
Identities = 51/275 (18%), Positives = 117/275 (42%), Gaps = 5/275 (1%)
Query: 22 YEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARK---AGGQTEINSLRASFD 78
Y+ L + +G CK + +L+QRA E Y K L ++A K A T + + +++
Sbjct: 14 YKNLKEFSQNGENFCKQVTSVLQQRANLEISYAKGLQKLASKLSKALQNTRKSCVSSAWA 73
Query: 79 SLKQQMENVGSSHIQLALTLR-EELRSLEEFRERQKEQRKKYEAVMDRVQKSKLSLYKKA 137
+ M++ H +L + E ++ + Q+++RK + +++ +S + +
Sbjct: 74 WASEGMKSTADLHQKLGKAIELEAIKPTYQVLNVQEKKRKSLDNEVEKTANLVISNWNQQ 133
Query: 138 MESKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQ 197
+++KK + + Q E + +K+ K NK + + + + Y Q
Sbjct: 134 IKAKKKLMVSTKKHEALFQLVESSKQSMTEKEKRKLLNKLTKSTEKLEKEDENYYQKNMA 193
Query: 198 LEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLE 257
R +WE ++ E +R+ +L N L +S +S+ + ++ +
Sbjct: 194 GYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAIS 253
Query: 258 GCSIDADIDSFIQAKS-TGTEPPAPVPYQNYYDRE 291
I+ DI + ++ + TE + +Y++ +
Sbjct: 254 KIDIEKDIQAVMEETAILSTENKSEFLLTDYFEED 288
Score = 52.8 bits (125), Expect = 6e-07
Identities = 22/52 (42%), Positives = 35/52 (67%)
Query: 365 RALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEKL 416
+ALY + A+ DEL+L GDI+ + + E+GWW NG++G P +Y+E+L
Sbjct: 444 KALYSFQARQDDELNLEKGDIVIIHEKKEEGWWFGSLNGKKGHFPAAYVEEL 495
>gi|78000167 sorbin and SH3 domain containing 1 isoform 5 [Homo
sapiens]
Length = 905
Score = 56.2 bits (134), Expect = 5e-08
Identities = 47/152 (30%), Positives = 72/152 (47%), Gaps = 21/152 (13%)
Query: 285 QNYYDREVTPLTSSPGIQPSC--GMIKR--------FSGL-LHGSPKTTSLAASAASTET 333
+N+Y+ + P TS GI P +IKR + L SP ++ A+ S +
Sbjct: 753 ENWYEGRI-PGTSRQGIFPITYVDVIKRPLVKNPVDYMDLPFSSSPSRSATASPQLSHHS 811
Query: 334 LTPTPERNEGVYTAIAVQEIQGNPASPAQE-------YRALYDYTAQNPDELDLSAGDIL 386
L P+ E + + Q Q + Y+ALY Y QN DEL+L GDI+
Sbjct: 812 LRAGPDLTESEKSYVQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIV 871
Query: 387 EVILEGEDGWW--TVERNGQRGFVPGSYLEKL 416
+V+ + +DGW+ T R Q G PG+Y++ L
Sbjct: 872 DVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPL 903
Score = 41.6 bits (96), Expect = 0.001
Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 3/62 (4%)
Query: 355 GNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLE 414
G+ PA RA +D+ AQ EL L GDI+ + + + W+ E +G+ G P +Y+E
Sbjct: 643 GSEMRPA---RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIE 699
Query: 415 KL 416
L
Sbjct: 700 LL 701
>gi|39930351 dynamin binding protein [Homo sapiens]
Length = 1577
Score = 55.8 bits (133), Expect = 7e-08
Identities = 26/68 (38%), Positives = 41/68 (60%), Gaps = 4/68 (5%)
Query: 352 EIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVI----LEGEDGWWTVERNGQRGF 407
E G+ A Q Y A+Y + A+NP+EL +SA L+++ + G WW E NG++G+
Sbjct: 1506 EPDGSEAEGNQVYFAVYTFKARNPNELSVSANQKLKILEFKDVTGNTEWWLAEVNGKKGY 1565
Query: 408 VPGSYLEK 415
VP +Y+ K
Sbjct: 1566 VPSNYIRK 1573
Score = 43.1 bits (100), Expect = 5e-04
Identities = 21/52 (40%), Positives = 30/52 (57%)
Query: 365 RALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEKL 416
RAL +AQ +ELD GD++ +I E GW+ E G+RG P ++E L
Sbjct: 151 RALMGLSAQLDEELDFREGDVITIIGVPEPGWFEGELEGRRGIFPEGFVELL 202
Score = 39.3 bits (90), Expect = 0.007
Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 2/76 (2%)
Query: 341 NEGVYTAIAVQEI--QGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWT 398
N V T + +EI + P ALY + A P+ELD GD + ++ EDGW
Sbjct: 223 NGEVDTPVGEEEIGPDEDEEEPGTYGVALYRFQALEPNELDFEVGDKIRILATLEDGWLE 282
Query: 399 VERNGQRGFVPGSYLE 414
G+ G P +++
Sbjct: 283 GSLKGRTGIFPYRFVK 298
Score = 35.0 bits (79), Expect = 0.13
Identities = 16/50 (32%), Positives = 28/50 (56%)
Query: 365 RALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLE 414
RA++D+ +EL L GDI+EV+ ++ W ++ G P S++E
Sbjct: 8 RAIFDFCPSVSEELPLFVGDIIEVLAVVDEFWLLGKKEDVTGQFPSSFVE 57
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,660,334
Number of Sequences: 37866
Number of extensions: 711880
Number of successful extensions: 5426
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 337
Number of HSP's successfully gapped in prelim test: 592
Number of HSP's that attempted gapping in prelim test: 3440
Number of HSP's gapped (non-prelim): 2032
length of query: 416
length of database: 18,247,518
effective HSP length: 105
effective length of query: 311
effective length of database: 14,271,588
effective search space: 4438463868
effective search space used: 4438463868
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.