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Search of human proteins with 19923844
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19923844 coiled-coil domain containing 82 [Homo sapiens]
(544 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19923844 coiled-coil domain containing 82 [Homo sapiens] 1098 0.0
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 67 5e-11
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 67 5e-11
gi|217330641 IWS1 homolog [Homo sapiens] 62 2e-09
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo... 61 3e-09
gi|24415404 MDN1, midasin homolog [Homo sapiens] 59 9e-09
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 58 2e-08
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 58 3e-08
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 58 3e-08
gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo ... 57 3e-08
gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo s... 57 3e-08
gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo sa... 57 3e-08
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 57 4e-08
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 57 4e-08
gi|148746195 trichohyalin [Homo sapiens] 56 1e-07
gi|27597090 suppressor of Ty 6 homolog [Homo sapiens] 56 1e-07
gi|221219020 NYD-SP11 protein [Homo sapiens] 55 1e-07
gi|4826657 caldesmon 1 isoform 2 [Homo sapiens] 55 1e-07
gi|15149465 caldesmon 1 isoform 5 [Homo sapiens] 55 2e-07
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 53 6e-07
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 53 6e-07
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 53 6e-07
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 53 8e-07
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 52 1e-06
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ... 52 1e-06
gi|115529449 upstream binding transcription factor, RNA polymera... 52 1e-06
gi|115529451 upstream binding transcription factor, RNA polymera... 52 1e-06
gi|7657671 upstream binding transcription factor, RNA polymerase... 52 1e-06
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa... 52 1e-06
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 52 2e-06
>gi|19923844 coiled-coil domain containing 82 [Homo sapiens]
Length = 544
Score = 1098 bits (2841), Expect = 0.0
Identities = 544/544 (100%), Positives = 544/544 (100%)
Query: 1 MIHVRRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDES 60
MIHVRRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDES
Sbjct: 1 MIHVRRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDES 60
Query: 61 FENDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRN 120
FENDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRN
Sbjct: 61 FENDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRN 120
Query: 121 IDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRG 180
IDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRG
Sbjct: 121 IDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRG 180
Query: 181 KRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKL 240
KRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKL
Sbjct: 181 KRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKL 240
Query: 241 QKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVV 300
QKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVV
Sbjct: 241 QKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVV 300
Query: 301 QDEEGDEENKNQQGEKLTTSQLKLVKQNSLYSFSDHYTHFERVVKALLINALDESFLGTL 360
QDEEGDEENKNQQGEKLTTSQLKLVKQNSLYSFSDHYTHFERVVKALLINALDESFLGTL
Sbjct: 301 QDEEGDEENKNQQGEKLTTSQLKLVKQNSLYSFSDHYTHFERVVKALLINALDESFLGTL 360
Query: 361 YDGTRQKSYAKDMLTSLHYLDNRFVQPRLESLVSRSRWKEQYKERVENYSNVSIHLKNPE 420
YDGTRQKSYAKDMLTSLHYLDNRFVQPRLESLVSRSRWKEQYKERVENYSNVSIHLKNPE
Sbjct: 361 YDGTRQKSYAKDMLTSLHYLDNRFVQPRLESLVSRSRWKEQYKERVENYSNVSIHLKNPE 420
Query: 421 NCSCQACGLHRYCKYSVHLSGELYNTRTMQIDNFMSHDKQVFTVGRICASRTRIYHKLKH 480
NCSCQACGLHRYCKYSVHLSGELYNTRTMQIDNFMSHDKQVFTVGRICASRTRIYHKLKH
Sbjct: 421 NCSCQACGLHRYCKYSVHLSGELYNTRTMQIDNFMSHDKQVFTVGRICASRTRIYHKLKH 480
Query: 481 FKFKLYQECCTIAMTEEVEDEQVKETVERIFRRSKENGWIKEKYGQLEEYLNFADYFQEE 540
FKFKLYQECCTIAMTEEVEDEQVKETVERIFRRSKENGWIKEKYGQLEEYLNFADYFQEE
Sbjct: 481 FKFKLYQECCTIAMTEEVEDEQVKETVERIFRRSKENGWIKEKYGQLEEYLNFADYFQEE 540
Query: 541 KFEL 544
KFEL
Sbjct: 541 KFEL 544
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 66.6 bits (161), Expect = 5e-11
Identities = 68/298 (22%), Positives = 133/298 (44%), Gaps = 22/298 (7%)
Query: 41 DEELDSEEFDSDE---ELDSDESFENDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDS 97
+E +D ++F+ E E + S N +E K + P E E K EG+ S
Sbjct: 423 EEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAE-EGCPEKESEEGCPKRGFEGSCS 481
Query: 98 KCLINSGN---GSTYEEETNKIKHRNIDLQDQEKHLSQE-DNDLNKQTGQII-------E 146
+ GN GS + + K + + +E L++E ++DLNK++ + + E
Sbjct: 482 QKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEE 541
Query: 147 DDQEKHLSQEDNDLNKQTG---QIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVR 203
DD EK ++ ++ + G + E+ LE++ + G K L + D E +++D
Sbjct: 542 DDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDK-ELEENDSENS 600
Query: 204 KVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFED 263
+ +V+++EGS E ++ + EK EK+ + K+ G + D
Sbjct: 601 EFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAAD 660
Query: 264 SEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEKLTTSQ 321
+ E + +++ EE ++ + DED D ++D + E D+ N+ E+ +S+
Sbjct: 661 KKAEEGDADEKLFEESDD---KEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSE 715
Score = 37.7 bits (86), Expect = 0.027
Identities = 43/161 (26%), Positives = 70/161 (43%), Gaps = 23/161 (14%)
Query: 41 DEELDSEEFD--SDEELDSDESFEN--DEELDSNKGPDCNKTPGSERELNLSKIQSEGND 96
DEE EFD SDE+ + ++++E D+E D + + G E K EG+
Sbjct: 612 DEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEA---ADKKAEEGDA 668
Query: 97 SKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQE 156
+ L + E+ K +++D ++ L ED+D N++ ED EK +
Sbjct: 669 DEKLFEESDDKEDEDADGK------EVEDADEKLF-EDDDSNEKLFDEEEDSSEKLF--D 719
Query: 157 DNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDD 197
D+D G +EE + G SS + SD+ DD
Sbjct: 720 DSDERGTLGGF--GSVEEGPLSTG-----SSFILSSDDDDD 753
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 66.6 bits (161), Expect = 5e-11
Identities = 68/298 (22%), Positives = 133/298 (44%), Gaps = 22/298 (7%)
Query: 41 DEELDSEEFDSDE---ELDSDESFENDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDS 97
+E +D ++F+ E E + S N +E K + P E E K EG+ S
Sbjct: 423 EEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAE-EGCPEKESEEGCPKRGFEGSCS 481
Query: 98 KCLINSGN---GSTYEEETNKIKHRNIDLQDQEKHLSQE-DNDLNKQTGQII-------E 146
+ GN GS + + K + + +E L++E ++DLNK++ + + E
Sbjct: 482 QKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEE 541
Query: 147 DDQEKHLSQEDNDLNKQTG---QIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVR 203
DD EK ++ ++ + G + E+ LE++ + G K L + D E +++D
Sbjct: 542 DDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDK-ELEENDSENS 600
Query: 204 KVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFED 263
+ +V+++EGS E ++ + EK EK+ + K+ G + D
Sbjct: 601 EFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAAD 660
Query: 264 SEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEKLTTSQ 321
+ E + +++ EE ++ + DED D ++D + E D+ N+ E+ +S+
Sbjct: 661 KKAEEGDADEKLFEESDD---KEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSE 715
Score = 37.7 bits (86), Expect = 0.027
Identities = 43/161 (26%), Positives = 70/161 (43%), Gaps = 23/161 (14%)
Query: 41 DEELDSEEFD--SDEELDSDESFEN--DEELDSNKGPDCNKTPGSERELNLSKIQSEGND 96
DEE EFD SDE+ + ++++E D+E D + + G E K EG+
Sbjct: 612 DEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEA---ADKKAEEGDA 668
Query: 97 SKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQE 156
+ L + E+ K +++D ++ L ED+D N++ ED EK +
Sbjct: 669 DEKLFEESDDKEDEDADGK------EVEDADEKLF-EDDDSNEKLFDEEEDSSEKLF--D 719
Query: 157 DNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDD 197
D+D G +EE + G SS + SD+ DD
Sbjct: 720 DSDERGTLGGF--GSVEEGPLSTG-----SSFILSSDDDDD 753
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 61.6 bits (148), Expect = 2e-09
Identities = 79/326 (24%), Positives = 141/326 (43%), Gaps = 30/326 (9%)
Query: 8 ETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDE-- 65
E+ K V + +S R S ++ L DSE D SD EN+E
Sbjct: 212 ESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDS--ENEELP 269
Query: 66 ----ELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNI 121
++ P N+ SE E L K + ++S+ + E+ ++ K +
Sbjct: 270 KPRISDSESEDPPRNQASDSENE-ELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPE 328
Query: 122 DLQDQEKHLSQEDNDLNKQT--GQIIEDDQEKHLSQ-EDNDLNKQTGQIIEDDLEEEDIK 178
D ++ ED ++ + D ++ H S E+ + KQ ED+ E E+ K
Sbjct: 329 SDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEK 388
Query: 179 RGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVE-DEGSSVEMEQKTP--EKTLAAQ 235
KRK ++V+ DS++ + K K+ R V + D+ S + K+ EKT+A+
Sbjct: 389 VAKRK--AAVLSDSEDEE-------KASAKKSRVVSDADDSDSDAVSDKSGKREKTIASD 439
Query: 236 KREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSD----EVDEEEEEDNYESDEDGD 291
E+ K ELS +++ ++ G D E +E +D DEEEEE + ED +
Sbjct: 440 SEEEAGK--ELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLE 497
Query: 292 DYIIDDFVVQDEEGDEENKNQQGEKL 317
+ + V + E+ D ++ ++G+ +
Sbjct: 498 EEKGETQVKEAEDSDSDDNIKRGKHM 523
Score = 45.1 bits (105), Expect = 2e-04
Identities = 62/311 (19%), Positives = 110/311 (35%), Gaps = 25/311 (8%)
Query: 12 NSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDS----EEFDSDEELDSDESFENDEEL 67
+ + V EQ S D +R S ++ D ++ L + ++DE L+ + S EEL
Sbjct: 28 DGEDDVNEQHSGSDTGSVERHSENETSDREDGLPKGHHVTDSENDEPLNLNASDSESEEL 87
Query: 68 DSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQE 127
K D SE SE D +N + EET K+ D +++E
Sbjct: 88 HRQKDSDSE----SEERAEPPASDSENED----VNQHGSDSESEETRKLP--GSDSENEE 137
Query: 128 KHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSS 187
+ N+ G+ D E Q+ + +T ++ + + + + R + S
Sbjct: 138 LLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASD 197
Query: 188 VMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELS 247
+E + + P+ V D S ++ P + + E+L K +
Sbjct: 198 ---SENEEPPKPRMSDSESEELPKPQVSDSES-----EEPPRHQASDSENEELPKPRISD 249
Query: 248 KQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDE 307
+ R DSE E P D E E+ D ++ + V D E +
Sbjct: 250 SESEDPPRHQA---SDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEG 306
Query: 308 ENKNQQGEKLT 318
K + T
Sbjct: 307 PQKGPASDSET 317
Score = 43.1 bits (100), Expect = 6e-04
Identities = 46/272 (16%), Positives = 102/272 (37%), Gaps = 12/272 (4%)
Query: 45 DSEEFDSDEELDSDESFENDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSG 104
+SEE ++ DS+ + ++ D N+ K+ ++++ L+N
Sbjct: 83 ESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGH 142
Query: 105 NGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDL-NKQ 163
+ E+ K + ++++ +K + + + QI + + E+ + +D N++
Sbjct: 143 ASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEE 202
Query: 164 TGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEM 223
+ D E E++ + + S ++ DS+ + P+ + D S
Sbjct: 203 PPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSE------NEELPKPRISDSES---- 252
Query: 224 EQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDN 283
+ P + + E+L K + + R+ D E+ E SD E ++
Sbjct: 253 -EDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGP 311
Query: 284 YESDEDGDDYIIDDFVVQDEEGDEENKNQQGE 315
E D D++ D ENK + E
Sbjct: 312 ASDSETEDASRHKQKPESDDDSDRENKGEDTE 343
Score = 31.6 bits (70), Expect = 1.9
Identities = 47/223 (21%), Positives = 81/223 (36%), Gaps = 35/223 (15%)
Query: 123 LQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDL--------------NKQTGQII 168
+QD+ S ++D+N+Q E+H E +D N + +
Sbjct: 19 VQDERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGLPKGHHVTDSENDEPLNLN 78
Query: 169 EDDLEEEDIKRGK------RKRLSSVMCDSDESD------DSDILVRKVGVKRPRRVVED 216
D E E++ R K +R DS+ D DS+ + K P E+
Sbjct: 79 ASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETR---KLPGSDSEN 135
Query: 217 E----GSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSS 272
E G + + E + K A+ ++++L++ S + DSE E P
Sbjct: 136 EELLNGHASDSENEDVGKHPASD--SEIEELQKSPASDSETEDALKPQISDSESEEPPRH 193
Query: 273 DEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGE 315
D E EE D + + V D E +E ++Q +
Sbjct: 194 QASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASD 236
Score = 31.6 bits (70), Expect = 1.9
Identities = 40/172 (23%), Positives = 67/172 (38%), Gaps = 25/172 (14%)
Query: 162 KQTGQIIEDDLEEEDI--KRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEG- 218
+ +G EDD+ E+ G +R S E++ SD R+ G+ + V + E
Sbjct: 23 RDSGSDGEDDVNEQHSGSDTGSVERHS-------ENETSD---REDGLPKGHHVTDSEND 72
Query: 219 -------SSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPS 271
S E E+ +K ++ E+ + S + G D E E P
Sbjct: 73 EPLNLNASDSESEELHRQKDSDSESEERAEP--PASDSENEDVNQHGSDSESEETRKLPG 130
Query: 272 SDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEKLTTSQLK 323
SD + EE + + SD + +D + D E +E K+ + T LK
Sbjct: 131 SDS-ENEELLNGHASDSENED--VGKHPASDSEIEELQKSPASDSETEDALK 179
>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
[Homo sapiens]
Length = 666
Score = 60.8 bits (146), Expect = 3e-09
Identities = 64/310 (20%), Positives = 130/310 (41%), Gaps = 20/310 (6%)
Query: 32 SSISQLLDSDEELDSEEFDSDEELDSDESFENDEELDSNKG--PDCNKTPGSERELNLSK 89
+ + L SD + ++E DSD DSD EN + G D ++ S + N
Sbjct: 2 ADMEDLFGSDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKEL 61
Query: 90 IQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQII--ED 147
+ D +SG+ + E N+ + ++ H + +D+++ +G +D
Sbjct: 62 FGDDSEDEGASHHSGSDNHSERSDNR-----SEASERSDHEDNDPSDVDQHSGSEAPNDD 116
Query: 148 DQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGV 207
+ E H S + ++ G + +D K G+ + S D ++ +SD R G
Sbjct: 117 EDEGHRSDGGSHHSEAEG---SEKAHSDDEKWGREDK--SDQSDDEKIQNSDDEERAQGS 171
Query: 208 KRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKE 267
+ D+ E Q T ++ ++ Q+L E K S R D D EK+
Sbjct: 172 DEDKLQNSDDD---EKMQNTDDEERPQLSDDERQQLSEEEKANSDDERPVASD-NDDEKQ 227
Query: 268 SCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQ--QGEKLTTSQLKLV 325
+ ++ +EE SD++ ++ D+E ++++K++ +G L++
Sbjct: 228 NSDDEEQPQLSDEEKMQNSDDERPQASDEEHRHSDDEEEQDHKSESARGSDSEDEVLRMK 287
Query: 326 KQNSLYSFSD 335
++N++ S S+
Sbjct: 288 RKNAIASDSE 297
Score = 48.9 bits (115), Expect = 1e-05
Identities = 70/336 (20%), Positives = 140/336 (41%), Gaps = 41/336 (12%)
Query: 8 ETRRNSKSHVPEQKSRVDWRRTKRSSIS---QLLDSDEELDSEEFDSDEELDSDESFEND 64
E + K+H ++K W R +S S ++ +SD+E ++ D D+ +SD+ D
Sbjct: 131 EAEGSEKAHSDDEK----WGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDD----D 182
Query: 65 EELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQ 124
E++ + + + ER+ LS+ + +D + + S N +E+ N L
Sbjct: 183 EKMQNTDDEERPQLSDDERQ-QLSEEEKANSDDERPVASDND---DEKQNSDDEEQPQLS 238
Query: 125 DQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKR 184
D+EK Q +D Q D++ +H E+ +K D E+++ R KRK
Sbjct: 239 DEEK--MQNSDDERPQAS----DEEHRHSDDEEEQDHKSESARGSDS--EDEVLRMKRK- 289
Query: 185 LSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTP------EKTLAAQKRE 238
+++ DS+ D+++ G +D S + E K P ++ Q ++
Sbjct: 290 -NAIASDSEADSDTEVPKDNSGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQ 348
Query: 239 KLQKLKE--LSKQRSRQRRSSGRDF------EDSEKESCPSSDEVDEEEEEDNYESDEDG 290
+ + + E + + + G D E P + E+E ED DE+G
Sbjct: 349 EEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEG 408
Query: 291 DDYIIDDFVVQDEEGDEENKNQQGEKLTTSQLKLVK 326
+ V++ ++++G ++ S ++VK
Sbjct: 409 RTRL--KLKVENTIRWRIRRDEEGNEIKESNARIVK 442
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 59.3 bits (142), Expect = 9e-09
Identities = 64/303 (21%), Positives = 129/303 (42%), Gaps = 29/303 (9%)
Query: 34 ISQLLDSDEELDSEEFDSDEELDS-DESFENDEELDSNKGPDCNKTPGSERELNLSKIQS 92
+ +E D E+ DS ++ D + E E+ D + E+E + K S
Sbjct: 4699 VEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKM----HDGELEEQEEDDEKSDS 4754
Query: 93 EGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKH 152
EG D + NG EE +K+ R D+E+ +EDN ++TG ++++ +
Sbjct: 4755 EGGDLDKHMGDLNG----EEADKLDERLWGDDDEEEDEEEEDNK-TEETGPGMDEEDSEL 4809
Query: 153 LSQEDN--------DLNKQTGQIIEDDLEEEDIKRGKRKRLSSV-MCDSDESDDSDILVR 203
++++DN D ++Q + +++ E +D +G+ K + D DE++
Sbjct: 4810 VAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGN 4869
Query: 204 KVGVKRPRRV---------VEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQR 254
+ V P + ED+ + + + E+ + +EK ++ +++R
Sbjct: 4870 QEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETE 4929
Query: 255 RSSGRDFEDSEKESCPSSDEVDE-EEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQ 313
E E PS D+ E EEE D D+DGD + ++++ E K+++
Sbjct: 4930 TDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKE 4989
Query: 314 GEK 316
++
Sbjct: 4990 ADE 4992
Score = 53.5 bits (127), Expect = 5e-07
Identities = 64/309 (20%), Positives = 129/309 (41%), Gaps = 33/309 (10%)
Query: 33 SISQLLDSDEELD-SEEFDSDEELDSDESFENDEELDSNKGPDCNKTPGSERELNLSKIQ 91
S S + D ++ SE+FD E E D+E ++G D +K G +L+ +
Sbjct: 4716 SKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMG-----DLNGEE 4770
Query: 92 SEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEK 151
++ D + + EEE NK + + +++ L +D++L+ + Q+K
Sbjct: 4771 ADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDK 4830
Query: 152 HLSQEDNDLN-------KQTGQIIEDDLEEEDIK--RGKRKRL---------SSVMCDSD 193
+E+ + + K QI E D +E ++ G ++++ + DS+
Sbjct: 4831 KEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSE 4890
Query: 194 ESDDSDILVRKVGVKRP----RRVVEDEGSSVEMEQKTPEKTLAAQK-REKLQKLKELSK 248
+ + + + G + + E+ G E +T +Q +E + E K
Sbjct: 4891 DKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDK 4950
Query: 249 QRSRQRRSSGRDFEDSEKESCPS--SDEVDEEEEEDNYESDEDGDDYIIDD--FVVQDEE 304
+ +G D +D + P S+E + EE + E+DE+G + D F Q+EE
Sbjct: 4951 AEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEE 5010
Query: 305 GDEENKNQQ 313
E++ ++
Sbjct: 5011 EREDSDTEE 5019
Score = 36.2 bits (82), Expect = 0.079
Identities = 57/296 (19%), Positives = 107/296 (36%), Gaps = 41/296 (13%)
Query: 7 HETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSD-------------- 52
HE ++ + +S+ + S + +EE+D+ D D
Sbjct: 4920 HEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQ 4979
Query: 53 EELDSDESFENDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDS-KCLINSGNGSTYEE 111
++ ++ E DEE N D P E E S + + ++ + ++ G T E
Sbjct: 4980 QQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVE 5039
Query: 112 ETNKIKHRNIDLQDQEKHLSQEDN-----DLNKQTGQ----IIEDDQEKHLSQEDNDLNK 162
+ + EK +E++ D N+ G I + +KH + +
Sbjct: 5040 NMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKR 5099
Query: 163 QTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVE 222
+ GQ +++ D KRL +V D+D + ++P+ VED +
Sbjct: 5100 KPGQA-DNERSMGDHNERVHKRLRTV--------DTDSHAEQGPAQQPQAQVEDADAFEH 5150
Query: 223 MEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEE 278
++Q Q SK++ + + SG+D E+ E E E EE
Sbjct: 5151 IKQ--------GSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEE 5198
Score = 30.0 bits (66), Expect = 5.7
Identities = 17/73 (23%), Positives = 36/73 (49%)
Query: 243 LKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQD 302
+K++S Q + + + EK+ + D + E++ E ED D + D + +
Sbjct: 4686 MKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQ 4745
Query: 303 EEGDEENKNQQGE 315
EE DE++ ++ G+
Sbjct: 4746 EEDDEKSDSEGGD 4758
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 58.2 bits (139), Expect = 2e-08
Identities = 65/352 (18%), Positives = 152/352 (43%), Gaps = 31/352 (8%)
Query: 4 VRRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFEN 63
+RR E K ++ + W K + +L + E + + + +E++ E
Sbjct: 337 MRRQEEMMWEKEEKMRRQEEMMWE--KEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIRE 394
Query: 64 DEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDL 123
EE + + E+E + + + + + + I + +E KI H +
Sbjct: 395 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE-EKI-HEQEKI 452
Query: 124 QDQEKHLSQEDNDLNKQTGQIIEDDQ---EKHLSQEDNDLNKQTGQIIEDDLEEEDIKRG 180
+++EK QE ++ +Q +I E ++ +K E + KQ ++ + + D +
Sbjct: 453 REEEKR--QEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEK 510
Query: 181 KRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKL 240
R++ + ++ + + +R+ + ++ E E E E+K E+ Q++EK+
Sbjct: 511 IREQEEKMWRQEEKIREQEEKIRE----QEEKIREQEEMMQEQEEKMGEQEEKMQEQEKM 566
Query: 241 QKLKEL---SKQRSRQRRSSGRDFED---SEKESCPSSDEVDEEEEEDNYESDEDGDDYI 294
++ +E +++ R+++ R+ E+ ++E +E+ +E+EE +E +E
Sbjct: 567 RRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE------ 620
Query: 295 IDDFVVQDE--EGDEENKNQQGEKLTTSQLKLVKQNSLYSFSDHYTHFERVV 344
Q+E + EE +Q EK+ +++L +Q +H H E +
Sbjct: 621 --KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE--KMQEHQEHLEAAI 668
Score = 37.0 bits (84), Expect = 0.046
Identities = 45/254 (17%), Positives = 110/254 (43%), Gaps = 39/254 (15%)
Query: 111 EETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQE---------------KHLSQ 155
E+ KI+ + ++ QE+ + +++ + +Q + E +++ + L +
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEE 384
Query: 156 EDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDE----------SDDSDILVRKV 205
+ ++ K Q + EE+ ++ KR+ + M +E + + ++
Sbjct: 385 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE 444
Query: 206 GVKRPRRVVEDEGSSVE-----MEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRD 260
+ ++ E+E + E+K E+ +++EK+ + +++ KQ + R +
Sbjct: 445 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKM 504
Query: 261 FEDSEK-----ESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEE--GDEENKNQQ 313
+ EK E +E E+EE E +E + ++ + + EE G++E K Q+
Sbjct: 505 HDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQ--EEMMQEQEEKMGEQEEKMQE 562
Query: 314 GEKLTTSQLKLVKQ 327
EK+ + K+ +Q
Sbjct: 563 QEKMRRQEEKIREQ 576
Score = 33.9 bits (76), Expect = 0.39
Identities = 37/227 (16%), Positives = 101/227 (44%), Gaps = 16/227 (7%)
Query: 115 KIKHRNIDLQDQEKHLSQEDNDLN---KQTGQIIEDDQ----EKHLSQEDNDLNKQTGQI 167
++K +N LQ++ + + E +++ K+ + +E + ++ L E + L K+ +
Sbjct: 218 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 277
Query: 168 ---IEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEME 224
++ +EE ++ ++ M +E K+ + + ++E + E
Sbjct: 278 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE--WEEKIQEQEEKIREQEEKIREQEE 335
Query: 225 QKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNY 284
+ ++ + +K EK+++ +E+ ++ + R + E++ +++ E+E+
Sbjct: 336 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQ 395
Query: 285 ESDEDGDDYIIDDFVVQDEEG----DEENKNQQGEKLTTSQLKLVKQ 327
E ++ I + Q++E EE +Q EK+ + K+ +Q
Sbjct: 396 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ 442
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 57.8 bits (138), Expect = 3e-08
Identities = 61/294 (20%), Positives = 97/294 (32%), Gaps = 18/294 (6%)
Query: 21 KSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDES-FENDEELDSNKGPDCNKTP 79
K + D + S S DS + DS+ DS+ DSD S ++ + DS+ N +
Sbjct: 544 KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD 603
Query: 80 GSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNK 139
S+ S S+ +DS +S + S+ E + D D S +++D +
Sbjct: 604 SSD-----SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSD 658
Query: 140 QTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSD 199
+ D D+ + + D + D SS DSD SD SD
Sbjct: 659 SSNSSNSSDSSDSSDSSDSSSSSDSSN-SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSD 717
Query: 200 ILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGR 259
D SS + + + + S S
Sbjct: 718 ---------SSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768
Query: 260 DFEDS--EKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKN 311
D DS +S SSD D D+ +S D D + D ++ N
Sbjct: 769 DSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSN 822
Score = 51.6 bits (122), Expect = 2e-06
Identities = 61/294 (20%), Positives = 104/294 (35%), Gaps = 25/294 (8%)
Query: 40 SDEELDSEEFDSDEELDS----DESFENDEELDSNKGPDCNKTPGSERELNLSKIQSEGN 95
SDE +++ +S+ + +S D S+ +DE D+ G D + G+E + + S + +
Sbjct: 468 SDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSD---SKGAEDDDSDSTSDTNNS 524
Query: 96 DSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQ 155
DS N+GN + ++ K K + D + S + +D + + D S
Sbjct: 525 DSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSS-------DSDSSDSNSS 577
Query: 156 EDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVE 215
D+D + D + D SS DS +S DS K E
Sbjct: 578 SDSDSSDSDSS----DSSDSDSSDSSNSSDSSDSSDSSDSSDSS---DSSDSKSDSSKSE 630
Query: 216 DEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEV 275
+ S + + + + + S S SS S +S SSD
Sbjct: 631 SDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSS 690
Query: 276 DEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEKLTTSQLKLVKQNS 329
D + ++ ES + D D + D N N + S NS
Sbjct: 691 DSSDSSNSSESSDSSDSSDSD----SSDSSDSSNSNSSDSDSSNSSDSSDSSNS 740
Score = 51.2 bits (121), Expect = 2e-06
Identities = 57/335 (17%), Positives = 104/335 (31%), Gaps = 22/335 (6%)
Query: 8 ETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEEL 67
++ +S+S S D + SS S DSD S+ DS DS +S ++
Sbjct: 694 DSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSS 753
Query: 68 DSNKGPDCNKTPGS--------------ERELNLSKIQSEGNDSKCLINSGNG------- 106
DS+ D + + S + N S S+ +DS +S N
Sbjct: 754 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSS 813
Query: 107 -STYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTG 165
S+ + +N N + S + + G + S + +
Sbjct: 814 DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS 873
Query: 166 QIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQ 225
D + D SS +S +SD SD E S+
Sbjct: 874 SNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNS 933
Query: 226 KTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYE 285
+ + + ++ + S +S + + +S SS+ D + D+ +
Sbjct: 934 NSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSD 993
Query: 286 SDEDGDDYIIDDFVVQDEEGDEENKNQQGEKLTTS 320
S + D D + D N + +S
Sbjct: 994 SSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSS 1028
Score = 49.7 bits (117), Expect = 7e-06
Identities = 58/296 (19%), Positives = 89/296 (30%), Gaps = 13/296 (4%)
Query: 40 SDEELDSEEFDSDEELDSDESFENDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKC 99
SD SE DS + DSD S +D ++ D + + S N S+ +DS
Sbjct: 693 SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSN----SSDSSDSSD 748
Query: 100 LINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDND 159
NS + S + +N + S + + D S +D
Sbjct: 749 SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808
Query: 160 LNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGS 219
+ + D D SS DS +S DS G D +
Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDS-----SDGSDSDSSNRSDSSN 863
Query: 220 SVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEE 279
S + + + S S SS D DS SSD D
Sbjct: 864 SSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSN----SSDSSDSSN 919
Query: 280 EEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEKLTTSQLKLVKQNSLYSFSD 335
D+ ES D+ D + D + + + +S +S + SD
Sbjct: 920 SSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD 975
Score = 48.5 bits (114), Expect = 2e-05
Identities = 54/297 (18%), Positives = 93/297 (31%), Gaps = 8/297 (2%)
Query: 32 SSISQLLDSDEELDSEEFDSDEELDSDESFENDEELDSNKGPDCNKTPGSERELNL---- 87
S+ S DS+ S+ +S + DS +S ++ + DS+ D + + S N
Sbjct: 963 SNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSS 1022
Query: 88 -SKIQSEGNDSKCLINSGNGSTYEEETNKIKHRN-IDLQDQEKHLSQEDNDLNKQTGQII 145
S S +DS +S + S + ++ N D D D+ + +
Sbjct: 1023 NSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1082
Query: 146 EDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKV 205
E S + + D + D SS DS +S DS
Sbjct: 1083 ESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 1142
Query: 206 GVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDS- 264
+ SS + + + + S S D DS
Sbjct: 1143 DSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1202
Query: 265 -EKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEKLTTS 320
+S SSD D + D+ +S + D D + D N + + +S
Sbjct: 1203 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSS 1259
Score = 46.6 bits (109), Expect = 6e-05
Identities = 53/282 (18%), Positives = 92/282 (32%), Gaps = 10/282 (3%)
Query: 39 DSDEELDSEEFDSDEELDSDESFENDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSK 98
D+ DS+ + D+ + ++ +D + N G D N S + K S +DS
Sbjct: 500 DNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGK----GKSDSSDSDSS 555
Query: 99 CLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDN 158
NS + S + + + + D D S + +D + D + S + +
Sbjct: 556 DSSNSSDSSDSSDSDSSDSNSSSD-SDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSS 614
Query: 159 DLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEG 218
D + + + E D K SS SD SD+SD D
Sbjct: 615 DSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNS-----SDSS 669
Query: 219 SSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEE 278
S + + + S + S SS D DS S +S + D
Sbjct: 670 DSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSS 729
Query: 279 EEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEKLTTS 320
D+ +S D D + D + + + +S
Sbjct: 730 NSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 771
Score = 40.8 bits (94), Expect = 0.003
Identities = 64/319 (20%), Positives = 115/319 (36%), Gaps = 34/319 (10%)
Query: 29 TKRSSISQLLDSDEELDSEEFD---SDEELDSDESFENDEELDSNKGPDC-NKTPGSERE 84
TK + ++ D LD+ + + + D DE +DE+ ++ G D N + G E +
Sbjct: 224 TKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQ 283
Query: 85 LNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQI 144
+ + +DS NS + Y+ E + H +D K Q
Sbjct: 284 ---DHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQR 340
Query: 145 IEDDQE---KHLSQEDNDLNKQT-----GQIIEDDLEEEDIKRGKRKRLSSVMCDSDESD 196
IED Q+ + + +N + K++ G+ + +E + G R V ++ +
Sbjct: 341 IEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKE 400
Query: 197 DS---DILVRKVGVKRPRRVVEDEGSSVEME--QKTPEKTLAAQKREKLQKLKELSKQR- 250
D +++ K VK VV EG + E K + + +
Sbjct: 401 DKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSM 460
Query: 251 -----SRQRRSSGRDFEDSEKESCPS--------SDEVDEEEEEDNYESDEDGDDYIIDD 297
+ S+G D +SE ++ S SDE + + + ED D D
Sbjct: 461 QGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSD 520
Query: 298 FVVQDEEGDEENKNQQGEK 316
D G+ N N +K
Sbjct: 521 TNNSDSNGNGNNGNDDNDK 539
Score = 36.2 bits (82), Expect = 0.079
Identities = 27/118 (22%), Positives = 47/118 (39%), Gaps = 12/118 (10%)
Query: 40 SDEELDSEEFDSDEELDSDESFENDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKC 99
SD S+ DS + DS +S ++ + DS+ D N++ S S+ +DS
Sbjct: 1196 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS----------SDSSDSSD 1245
Query: 100 LINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQED 157
NS + S + ++ N + Q K S N+ + E H + +D
Sbjct: 1246 SSNSSDSSDSSDSSDSTSDSNDESDSQSK--SGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 57.8 bits (138), Expect = 3e-08
Identities = 80/372 (21%), Positives = 147/372 (39%), Gaps = 49/372 (13%)
Query: 19 EQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEELDSNKGPDCNKT 78
E+K R +R + + + L EEL++ + D ++ +S FE +E + S D
Sbjct: 234 EKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFE-EETVKSKVTVDTGVI 292
Query: 79 PGSERELNL---SKIQSEGNDSKCLINSGNGSTYEEETNKIKHRN-----------IDLQ 124
P SE + ++ +EG+ K G E+E K K + L+
Sbjct: 293 PASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLK 352
Query: 125 DQEKHLSQEDNDLNKQTGQI-IEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRK 183
++E+ +E+ + K+ ++ + +E+ L QE + KQ + ++ L++E K +
Sbjct: 353 EEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQ 412
Query: 184 R---------LSSVMCDSDESDDSDILVRKVGV------KRPRRVVEDEGSSVEMEQKTP 228
R L + E D L +K + K+ + +E + S ME
Sbjct: 413 REARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAA 472
Query: 229 EKTLAAQKREKLQKLKELSKQRSRQRRSSGRD-----FEDSEKESCPSS--------DEV 275
+ + EK + + + +G D D E E + +
Sbjct: 473 VEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPE 532
Query: 276 DEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEK-----LTTSQLKLVKQNSL 330
+EEEEE+ E DE+ ++ ++ + EGDEE++ EK L K + +S
Sbjct: 533 EEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSE 592
Query: 331 YSFSDHYTHFER 342
Y D T ER
Sbjct: 593 YDSDDDRTKEER 604
Score = 52.0 bits (123), Expect = 1e-06
Identities = 86/413 (20%), Positives = 168/413 (40%), Gaps = 71/413 (17%)
Query: 19 EQKSRVDWRRTKRSSISQLLDSDE--------ELDSEEFDSDEELDSDESFENDEELDSN 70
EQ+ + + K+ Q D D+ L+++ +D E + + EN+EE ++
Sbjct: 34 EQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTS 93
Query: 71 KGPDCNKTPGSERELNLSKIQS-EGNDSKCL------INSGNGSTYEEETNKIKHRNIDL 123
K G ++ + + + E DSK + +GS +++ NK L
Sbjct: 94 KDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNK-------L 146
Query: 124 QDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDN-DLNKQTGQIIEDDLEEEDIKRGKR 182
+ K +Q+ N K G ++D K + + + + ++G ++ L+ ++ +
Sbjct: 147 PKKAKGKAQKSN--KKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQ 204
Query: 183 KRLSSVMCDS-DESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQ 241
K +S +E DD+ ++ V K+ E+K E+ +++ KL+
Sbjct: 205 KNKPGPNIESGNEDDDASFKIKTVAQKKA-------------EKKERERKKRDEEKAKLR 251
Query: 242 KLKELS------KQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYII 295
KLKE K +S+Q+ S R FE+ +S + D E+ E+ +D
Sbjct: 252 KLKEKEELETGKKDQSKQKESQ-RKFEEETVKSKVTVDTGVIPASEEKAETPTAAED--- 307
Query: 296 DDFVVQDEEGDEENKNQQGEKLTTSQLKLVKQNSLYSFSDHYTHFERVVKALLINALDES 355
D EGD++ K+++ +K + + K+ + A+ E+
Sbjct: 308 ------DNEGDKKKKDKKKKKGEKEEKEKEKKKG--------------PSKATVKAMQEA 347
Query: 356 FLGTLYDGTRQKSYAKDMLTSLHYLD-NRFVQPRLESLVSRSRWKEQYKERVE 407
+ RQK ++ + L L+ R + RLE R R K++ KER E
Sbjct: 348 LAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQ-EKRERKKQKEKERKE 399
Score = 29.6 bits (65), Expect = 7.4
Identities = 31/136 (22%), Positives = 51/136 (37%), Gaps = 9/136 (6%)
Query: 41 DEELDSEEFDSDEELDSDESFENDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCL 100
+EE + EE + DEE + +E E + E D + + L K S+ S
Sbjct: 533 EEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSE 592
Query: 101 INSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDL---------NKQTGQIIEDDQEK 151
+S + T EE R I+ + E + L + TG+ D+ +
Sbjct: 593 YDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEKLRAPIICVLGHVDTGKTKILDKLR 652
Query: 152 HLSQEDNDLNKQTGQI 167
H +D + T QI
Sbjct: 653 HTHVQDGEAGGITQQI 668
>gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo
sapiens]
Length = 1188
Score = 57.4 bits (137), Expect = 3e-08
Identities = 68/337 (20%), Positives = 138/337 (40%), Gaps = 28/337 (8%)
Query: 11 RNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEELDSN 70
R H P+ K ++ S+ + L D+E+ E S+ E + D + E++ E
Sbjct: 408 RTVHHHEPKVKEE---KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIEL 464
Query: 71 KGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHL 130
K P + + +I+ E + K N +++ + + +L K+
Sbjct: 465 KSPRGRRRIARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNT 524
Query: 131 -SQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIK----------- 178
Q++ + KQ + D+E+ SQE + + E+D EED++
Sbjct: 525 PKQKEKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEED--EEDMEPCLTGTKVKVK 582
Query: 179 --RGKRKRLSSVMCDSDESDDSDI--LVRKVGVK-RPRRVVEDEGSSVEMEQKTPEKTLA 233
RGK +++ S E DD ++ LV G R V+ + +++ P+K
Sbjct: 583 YGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQK 642
Query: 234 AQKREKLQKLKELSKQRSRQRRSSGR-DFEDSEKESCP--SSDEVDEEEEEDNYESDEDG 290
+ + K K+ + RQ+ GR + + + P S + E + D+ SD +
Sbjct: 643 KKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSET 702
Query: 291 DDYIIDDFVVQD---EEGDEENKNQQGEKLTTSQLKL 324
+D + + + ++ ++ E+N+N +KL K+
Sbjct: 703 EDALEKNLINEELSLKDELEKNENLNDDKLDEENPKI 739
Score = 36.2 bits (82), Expect = 0.079
Identities = 47/222 (21%), Positives = 85/222 (38%), Gaps = 33/222 (14%)
Query: 42 EELDSEEFDSDEELDSDESFENDEELDSNKGPD---CNKTP----GSERELNLSKIQSEG 94
++L SE FDS E + + DE+ GP+ C++ + + ++ + E
Sbjct: 923 QQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVES 982
Query: 95 NDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLS 154
++S L++ + N + L E + ++D+ + I E+ QE
Sbjct: 983 SESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVKSESDITIEVDSIAEESQE---- 1038
Query: 155 QEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVV 214
L E + G ++S C + R+ G KRP
Sbjct: 1039 ----------------GLCERESANGFETNVASGTCSIIVQERES---REKGQKRPSD-- 1077
Query: 215 EDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRS 256
+ G + +++TP++T AA K EK EL S +R S
Sbjct: 1078 GNSGLMAKKQKRTPKRTSAAAKNEK-NGTDELDNMNSTERIS 1118
Score = 32.0 bits (71), Expect = 1.5
Identities = 34/149 (22%), Positives = 56/149 (37%), Gaps = 36/149 (24%)
Query: 2 IHVRRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESF 61
I ++ RR V K ++ +T+ D ++ D+E D D++ ++ E
Sbjct: 462 IELKSPRGRRRIARDVNSIKKEIEEEKTE--------DKLKDNDTENKDVDDDYETAEKK 513
Query: 62 END-----------------EELDSNKGPDCNKTPGSERELNLSKIQSEGND-------- 96
EN+ ++ DS+K D + ERE SK SEG +
Sbjct: 514 ENELLLGRKNTPKQKEKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPC 573
Query: 97 ---SKCLINSGNGSTYEEETNKIKHRNID 122
+K + G G T + IK ID
Sbjct: 574 LTGTKVKVKYGRGKTQKIYEASIKSTEID 602
Score = 29.6 bits (65), Expect = 7.4
Identities = 50/246 (20%), Positives = 100/246 (40%), Gaps = 47/246 (19%)
Query: 56 DSDESFENDEELDSNKG--PDCNKTPGSERELNLSKI-QSEGNDSKCLINSGNGSTYEEE 112
DS++ + DEE +K P T S LSK SEG C
Sbjct: 650 DSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCS------------ 697
Query: 113 TNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDL 172
D E + E N +N++ ++D+ EK+ + D+ L+++ +I L
Sbjct: 698 -----------SDSETEDALEKNLINEELS--LKDELEKNENLNDDKLDEENPKISAHIL 744
Query: 173 EEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTL 232
+E D R + + L ++ + E++ ++V+ G+ +E ++ ++
Sbjct: 745 KEND--RTQMQPLETLKLEVGENE---------------QIVQIFGNKMEKTEEVKKEAE 787
Query: 233 AAQK-REKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGD 291
+ K + + K K+LS + + S G++ SE S E+ + ++ + ED
Sbjct: 788 KSPKGKGRRSKTKDLSLEIIK-ISSFGQNEAGSEPHIEAHSLELSSLDNKNFSSATEDEI 846
Query: 292 DYIIDD 297
D + +
Sbjct: 847 DQCVKE 852
>gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo
sapiens]
Length = 1203
Score = 57.4 bits (137), Expect = 3e-08
Identities = 68/337 (20%), Positives = 138/337 (40%), Gaps = 28/337 (8%)
Query: 11 RNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEELDSN 70
R H P+ K ++ S+ + L D+E+ E S+ E + D + E++ E
Sbjct: 408 RTVHHHEPKVKEE---KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIEL 464
Query: 71 KGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHL 130
K P + + +I+ E + K N +++ + + +L K+
Sbjct: 465 KSPRGRRRIARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNT 524
Query: 131 -SQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIK----------- 178
Q++ + KQ + D+E+ SQE + + E+D EED++
Sbjct: 525 PKQKEKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEED--EEDMEPCLTGTKVKVK 582
Query: 179 --RGKRKRLSSVMCDSDESDDSDI--LVRKVGVK-RPRRVVEDEGSSVEMEQKTPEKTLA 233
RGK +++ S E DD ++ LV G R V+ + +++ P+K
Sbjct: 583 YGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQK 642
Query: 234 AQKREKLQKLKELSKQRSRQRRSSGR-DFEDSEKESCP--SSDEVDEEEEEDNYESDEDG 290
+ + K K+ + RQ+ GR + + + P S + E + D+ SD +
Sbjct: 643 KKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSET 702
Query: 291 DDYIIDDFVVQD---EEGDEENKNQQGEKLTTSQLKL 324
+D + + + ++ ++ E+N+N +KL K+
Sbjct: 703 EDALEKNLINEELSLKDELEKNENLNDDKLDEENPKI 739
Score = 34.7 bits (78), Expect = 0.23
Identities = 42/205 (20%), Positives = 79/205 (38%), Gaps = 32/205 (15%)
Query: 42 EELDSEEFDSDEELDSDESFENDEELDSNKGPD---CNKTP----GSERELNLSKIQSEG 94
++L SE FDS E + + DE+ GP+ C++ + + ++ + E
Sbjct: 923 QQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVES 982
Query: 95 NDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLS 154
++S L++ + N + L E + ++D+ + I E+ QE
Sbjct: 983 SESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVKSESDITIEVDSIAEESQE---- 1038
Query: 155 QEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVV 214
L E + G ++S C + R+ G KRP
Sbjct: 1039 ----------------GLCERESANGFETNVASGTCSIIVQERES---REKGQKRPSD-- 1077
Query: 215 EDEGSSVEMEQKTPEKTLAAQKREK 239
+ G + +++TP++T AA K EK
Sbjct: 1078 GNSGLMAKKQKRTPKRTSAAAKNEK 1102
Score = 32.0 bits (71), Expect = 1.5
Identities = 34/149 (22%), Positives = 56/149 (37%), Gaps = 36/149 (24%)
Query: 2 IHVRRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESF 61
I ++ RR V K ++ +T+ D ++ D+E D D++ ++ E
Sbjct: 462 IELKSPRGRRRIARDVNSIKKEIEEEKTE--------DKLKDNDTENKDVDDDYETAEKK 513
Query: 62 END-----------------EELDSNKGPDCNKTPGSERELNLSKIQSEGND-------- 96
EN+ ++ DS+K D + ERE SK SEG +
Sbjct: 514 ENELLLGRKNTPKQKEKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPC 573
Query: 97 ---SKCLINSGNGSTYEEETNKIKHRNID 122
+K + G G T + IK ID
Sbjct: 574 LTGTKVKVKYGRGKTQKIYEASIKSTEID 602
Score = 29.6 bits (65), Expect = 7.4
Identities = 50/246 (20%), Positives = 100/246 (40%), Gaps = 47/246 (19%)
Query: 56 DSDESFENDEELDSNKG--PDCNKTPGSERELNLSKI-QSEGNDSKCLINSGNGSTYEEE 112
DS++ + DEE +K P T S LSK SEG C
Sbjct: 650 DSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCS------------ 697
Query: 113 TNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDL 172
D E + E N +N++ ++D+ EK+ + D+ L+++ +I L
Sbjct: 698 -----------SDSETEDALEKNLINEELS--LKDELEKNENLNDDKLDEENPKISAHIL 744
Query: 173 EEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTL 232
+E D R + + L ++ + E++ ++V+ G+ +E ++ ++
Sbjct: 745 KEND--RTQMQPLETLKLEVGENE---------------QIVQIFGNKMEKTEEVKKEAE 787
Query: 233 AAQK-REKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGD 291
+ K + + K K+LS + + S G++ SE S E+ + ++ + ED
Sbjct: 788 KSPKGKGRRSKTKDLSLEIIK-ISSFGQNEAGSEPHIEAHSLELSSLDNKNFSSATEDEI 846
Query: 292 DYIIDD 297
D + +
Sbjct: 847 DQCVKE 852
>gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo
sapiens]
Length = 1257
Score = 57.4 bits (137), Expect = 3e-08
Identities = 68/337 (20%), Positives = 138/337 (40%), Gaps = 28/337 (8%)
Query: 11 RNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEELDSN 70
R H P+ K ++ S+ + L D+E+ E S+ E + D + E++ E
Sbjct: 408 RTVHHHEPKVKEE---KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIEL 464
Query: 71 KGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHL 130
K P + + +I+ E + K N +++ + + +L K+
Sbjct: 465 KSPRGRRRIARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNT 524
Query: 131 -SQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIK----------- 178
Q++ + KQ + D+E+ SQE + + E+D EED++
Sbjct: 525 PKQKEKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEED--EEDMEPCLTGTKVKVK 582
Query: 179 --RGKRKRLSSVMCDSDESDDSDI--LVRKVGVK-RPRRVVEDEGSSVEMEQKTPEKTLA 233
RGK +++ S E DD ++ LV G R V+ + +++ P+K
Sbjct: 583 YGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQK 642
Query: 234 AQKREKLQKLKELSKQRSRQRRSSGR-DFEDSEKESCP--SSDEVDEEEEEDNYESDEDG 290
+ + K K+ + RQ+ GR + + + P S + E + D+ SD +
Sbjct: 643 KKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSET 702
Query: 291 DDYIIDDFVVQD---EEGDEENKNQQGEKLTTSQLKL 324
+D + + + ++ ++ E+N+N +KL K+
Sbjct: 703 EDALEKNLINEELSLKDELEKNENLNDDKLDEENPKI 739
Score = 34.7 bits (78), Expect = 0.23
Identities = 42/205 (20%), Positives = 79/205 (38%), Gaps = 32/205 (15%)
Query: 42 EELDSEEFDSDEELDSDESFENDEELDSNKGPD---CNKTP----GSERELNLSKIQSEG 94
++L SE FDS E + + DE+ GP+ C++ + + ++ + E
Sbjct: 923 QQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVES 982
Query: 95 NDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLS 154
++S L++ + N + L E + ++D+ + I E+ QE
Sbjct: 983 SESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVKSESDITIEVDSIAEESQE---- 1038
Query: 155 QEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVV 214
L E + G ++S C + R+ G KRP
Sbjct: 1039 ----------------GLCERESANGFETNVASGTCSIIVQERES---REKGQKRPSD-- 1077
Query: 215 EDEGSSVEMEQKTPEKTLAAQKREK 239
+ G + +++TP++T AA K EK
Sbjct: 1078 GNSGLMAKKQKRTPKRTSAAAKNEK 1102
Score = 32.0 bits (71), Expect = 1.5
Identities = 34/149 (22%), Positives = 56/149 (37%), Gaps = 36/149 (24%)
Query: 2 IHVRRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESF 61
I ++ RR V K ++ +T+ D ++ D+E D D++ ++ E
Sbjct: 462 IELKSPRGRRRIARDVNSIKKEIEEEKTE--------DKLKDNDTENKDVDDDYETAEKK 513
Query: 62 END-----------------EELDSNKGPDCNKTPGSERELNLSKIQSEGND-------- 96
EN+ ++ DS+K D + ERE SK SEG +
Sbjct: 514 ENELLLGRKNTPKQKEKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPC 573
Query: 97 ---SKCLINSGNGSTYEEETNKIKHRNID 122
+K + G G T + IK ID
Sbjct: 574 LTGTKVKVKYGRGKTQKIYEASIKSTEID 602
Score = 29.6 bits (65), Expect = 7.4
Identities = 50/246 (20%), Positives = 100/246 (40%), Gaps = 47/246 (19%)
Query: 56 DSDESFENDEELDSNKG--PDCNKTPGSERELNLSKI-QSEGNDSKCLINSGNGSTYEEE 112
DS++ + DEE +K P T S LSK SEG C
Sbjct: 650 DSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCS------------ 697
Query: 113 TNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDL 172
D E + E N +N++ ++D+ EK+ + D+ L+++ +I L
Sbjct: 698 -----------SDSETEDALEKNLINEELS--LKDELEKNENLNDDKLDEENPKISAHIL 744
Query: 173 EEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTL 232
+E D R + + L ++ + E++ ++V+ G+ +E ++ ++
Sbjct: 745 KEND--RTQMQPLETLKLEVGENE---------------QIVQIFGNKMEKTEEVKKEAE 787
Query: 233 AAQK-REKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGD 291
+ K + + K K+LS + + S G++ SE S E+ + ++ + ED
Sbjct: 788 KSPKGKGRRSKTKDLSLEIIK-ISSFGQNEAGSEPHIEAHSLELSSLDNKNFSSATEDEI 846
Query: 292 DYIIDD 297
D + +
Sbjct: 847 DQCVKE 852
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 57.0 bits (136), Expect = 4e-08
Identities = 53/302 (17%), Positives = 132/302 (43%), Gaps = 15/302 (4%)
Query: 16 HVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEELDSNKGPDC 75
H+ E K +++ + Q+ + + ++ +E E+ + E + ++ +G
Sbjct: 33 HIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQ--EGQVREQEGQVREQEG-QV 89
Query: 76 NKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDN 135
+ G RE + EG + G E+E +++ + +++QE + +++
Sbjct: 90 REQEGQVREQEGQVREQEGQ-----VREQEGQVREQE-GQVREQEGQVREQEGQVREQEG 143
Query: 136 DLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDD---LEEEDIKRGKRKRLSSVMCDS 192
+ +Q GQ+ E QE + +++ + +Q GQ+ E + E+E R + ++
Sbjct: 144 QVREQEGQVRE--QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQM 201
Query: 193 DESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREK-LQKLKELSKQRS 251
E ++ + K+ ++ E E + E++ E+ QK+E+ +QK +E +++
Sbjct: 202 GEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQE 261
Query: 252 RQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKN 311
Q R + E++ ++ ++EE+ E + + + Q E +E+ +
Sbjct: 262 EQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE 321
Query: 312 QQ 313
Q+
Sbjct: 322 QE 323
Score = 49.7 bits (117), Expect = 7e-06
Identities = 57/334 (17%), Positives = 148/334 (44%), Gaps = 26/334 (7%)
Query: 4 VRRHETR-RNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFE 62
VR E + R + V EQ+ +V R Q+ + + ++ +E E+ + E
Sbjct: 75 VREQEGQVREQEGQVREQEGQV------REQEGQVREQEGQVREQEGQVREQ--EGQVRE 126
Query: 63 NDEELDSNKGPDCNKTPGSERELNLSKIQSEGN--DSKCLINSGNGSTYEEETNKIKHRN 120
+ ++ +G + G RE + EG + + + G E+E +++ +
Sbjct: 127 QEGQVREQEG-QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE-GQVREQE 184
Query: 121 IDLQDQEKHLSQEDNDLNKQTGQIIEDD-----QEKHLSQEDNDLNKQTGQIIEDDLEEE 175
+++QE + +++ + +Q Q+ E + QE+ + +++ + KQ Q+ E + + +
Sbjct: 185 GQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQ 244
Query: 176 DIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQ 235
+ +K+ + ++ + + +R+ + ++ + E EQ+ + Q
Sbjct: 245 KQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQ 304
Query: 236 KREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYII 295
RE+ ++++E +Q Q G+ E++ +++ E++E+ + ++ G+
Sbjct: 305 MREQEEQMREQEEQMREQEEQMGK----QEEQMWEQKEQMWEQKEQMWKQEEQMGEQE-- 358
Query: 296 DDFVVQDEE--GDEENKNQQGEKLTTSQLKLVKQ 327
+ Q+E+ EE +Q E++ + ++ KQ
Sbjct: 359 EQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQ 392
Score = 42.0 bits (97), Expect = 0.001
Identities = 43/286 (15%), Positives = 124/286 (43%), Gaps = 16/286 (5%)
Query: 4 VRRHETR-RNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFE 62
VR E + R + V EQ+ +V R Q+ + + ++ +E E+ ++ E
Sbjct: 159 VREQEGQVREQEGQVREQEGQV------REQEGQVREQEGQMGEQEGQMGEQ--EEQMGE 210
Query: 63 NDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNID 122
+E++ + E+E + K + + + + + ++E +++ +
Sbjct: 211 QEEQMQKQE------EQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQE-EQMRKQEEQ 263
Query: 123 LQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKR 182
+++QE+ + +++ + KQ Q +++Q ++ + +Q + E E+E+ R +
Sbjct: 264 MREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQE 323
Query: 183 KRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQK 242
+++ E + ++ K+ ++ E E + E++ ++ +K+E+ +
Sbjct: 324 EQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMR 383
Query: 243 LKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDE 288
+E ++ ++ ++ +KE +E E++E + +E
Sbjct: 384 KQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 57.0 bits (136), Expect = 4e-08
Identities = 63/348 (18%), Positives = 150/348 (43%), Gaps = 28/348 (8%)
Query: 4 VRRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFEN 63
+RR E K ++ + W + ++ + + ++E E + E++ E
Sbjct: 398 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE--EKMHEQEKIRE 455
Query: 64 DEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDL 123
EE + + E+E + + + + + + I + +E KI H +
Sbjct: 456 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQE-EKI-HEQEKI 513
Query: 124 QDQEKHLSQEDNDLNKQTGQIIEDD----QEKHLSQEDNDLNKQTGQIIEDDLEEEDIKR 179
+++EK QE ++ +Q +I E + Q++ + +++ + KQ ++ + + D +
Sbjct: 514 REEEKR--QEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEE 571
Query: 180 GKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKT-LAAQKRE 238
R++ V ++ + + +R+ + ++ E E + E E+K E+ ++ E
Sbjct: 572 KIREQEEKVWRQEEKIREQEEKIRE----QEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 627
Query: 239 KLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDF 298
K+Q+ +E +++ + R + + E E +E+ +E+EE +E +E
Sbjct: 628 KMQEQEEKMRRQEEKIREQEKKIREQE-EKIREQEEMMQEQEEKMWEQEE--------KM 678
Query: 299 VVQDE--EGDEENKNQQGEKLTTSQLKLVKQNSLYSFSDHYTHFERVV 344
Q+E + EE +Q EK+ +++L +Q +H H E +
Sbjct: 679 CEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE--KMQEHQEHLEAAI 724
Score = 39.7 bits (91), Expect = 0.007
Identities = 44/228 (19%), Positives = 103/228 (45%), Gaps = 14/228 (6%)
Query: 111 EETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDN--DLNKQTGQII 168
E+ KI+ + ++ QE+ + +++ + +Q +++ + +EK QE+ + ++ ++
Sbjct: 386 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQE-EMMWEKEEKMRRQEEMMWEKEEKIRELE 444
Query: 169 EDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTP 228
E E+E I+ + KR E ++ ++ E E E E+K
Sbjct: 445 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQ---EAKMWRQEEKIREQEEKIREQEEKMW 501
Query: 229 EKTLAAQKREKLQKLKELSKQRSRQRRSSG-RDFED--SEKESCPSSDEVDEEEEEDNYE 285
+ ++EK+++ ++ +Q R+ R+ E+ +KE +E ++EE +
Sbjct: 502 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWR 561
Query: 286 SDEDGDDYIIDDFVVQDEE---GDEENKNQQGEKLTTSQLKLVKQNSL 330
+E D ++ + + EE EE +Q EK+ + K+ +Q +
Sbjct: 562 QEEKMHDQ--EEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEM 607
Score = 34.3 bits (77), Expect = 0.30
Identities = 37/227 (16%), Positives = 101/227 (44%), Gaps = 16/227 (7%)
Query: 115 KIKHRNIDLQDQEKHLSQEDNDLN---KQTGQIIEDDQ----EKHLSQEDNDLNKQTGQI 167
++K +N LQ++ + + E +++ K+ + +E + ++ L E + L K+ +
Sbjct: 279 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 338
Query: 168 ---IEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEME 224
++ +EE ++ ++ M +E K+ + + ++E + E
Sbjct: 339 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE--WEEKIQEQEEKIREQEEKIREQEE 396
Query: 225 QKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNY 284
+ ++ + +K EK+++ +E+ ++ + R + E++ +++ E+E+
Sbjct: 397 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 456
Query: 285 ESDEDGDDYIIDDFVVQDEEG----DEENKNQQGEKLTTSQLKLVKQ 327
E ++ I + Q++E EE +Q EK+ + K+ +Q
Sbjct: 457 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQ 503
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 55.8 bits (133), Expect = 1e-07
Identities = 69/342 (20%), Positives = 136/342 (39%), Gaps = 38/342 (11%)
Query: 19 EQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEELDSNK----GPD 74
E++ R + R R QL +E+L EE + + + + D++L + G +
Sbjct: 919 EKRRRQEQERQYREE-EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEE 977
Query: 75 CNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQED 134
K ERE + + + + L+ +E + + +LQ +E+ L +E+
Sbjct: 978 PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE 1037
Query: 135 NDLNKQTGQIIEDDQEKHLSQEDNDL-------------------NKQTGQIIEDDLEEE 175
+ + + + +E+ L QE+ L ++ Q E L EE
Sbjct: 1038 REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE 1097
Query: 176 DIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTL--A 233
KR +++R + + + + L+R+ KR R+ +E + E Q+ E+ L
Sbjct: 1098 PEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREE 1157
Query: 234 AQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYE-----SDE 288
+KR + + ++ ++ Q+ E+ EK + EEEE + DE
Sbjct: 1158 PEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDE 1217
Query: 289 DGDDYIIDDFVVQDEEGDEENK-------NQQGEKLTTSQLK 323
D + + + E +NK N+Q +L SQL+
Sbjct: 1218 DQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLR 1259
Score = 52.0 bits (123), Expect = 1e-06
Identities = 56/289 (19%), Positives = 125/289 (43%), Gaps = 36/289 (12%)
Query: 3 HVRRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFE 62
H ++HE R + EQ+ R DW + + + ++E ++ D+E + E +
Sbjct: 434 HEQKHEQERREQRLKREQEERRDWLKREEETERH----EQERRKQQLKRDQEEERRERWL 489
Query: 63 NDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNID 122
EE + + + RE L + Q E + + +EE +++ R
Sbjct: 490 KLEEEERREQQE-------RREQQLRREQEERREQRL--------KRQEEEERLQQR--- 531
Query: 123 LQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKR 182
E+ L +E + +Q +++ ++EK L QE + + Q ++ ++ +KR +
Sbjct: 532 -LRSEQQLRREQEERREQ---LLKREEEKRLEQERREQRLKREQ---EERRDQLLKREEE 584
Query: 183 KRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQ--KREKL 240
+R + + +E L +++ + R+ ++E ++++ PE+ Q K E+
Sbjct: 585 RRQQRLKREQEER-----LEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ 639
Query: 241 QKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDED 289
++ ++ +R +Q R R + E+E + + EEE E E+
Sbjct: 640 EERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEE 688
Score = 51.6 bits (122), Expect = 2e-06
Identities = 69/331 (20%), Positives = 141/331 (42%), Gaps = 30/331 (9%)
Query: 5 RRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFEND 64
RR +R+ EQ R + + KR + + + L E + ++D F +
Sbjct: 1283 RRRWQQRDRHFPEEEQLEREEQKEAKRRD-RKSQEEKQLLREEREEKRRRQETDRKFREE 1341
Query: 65 EELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKH-RNIDL 123
E+L + + +R+ +++ + K L E E +K + +
Sbjct: 1342 EQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRC 1401
Query: 124 QDQEKHLSQE-DNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKR 182
Q++E+ L Q+ D ++ Q+ ++++ +E+ + +Q + LEEE R +R
Sbjct: 1402 QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERE--RKFLEEEQQLRQER 1459
Query: 183 KRL----SSVMCDSDESD------DSDILVRKVGVKRP---RRVVEDEGSSVEMEQK--T 227
R ++ + +E D L + ++R R+ E E S E E+K
Sbjct: 1460 HRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLE 1519
Query: 228 PEKTLAAQKREK--LQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYE 285
E+ L Q+R++ LQ+ ++L +Q Q+R RD + E+E ++ +E EE
Sbjct: 1520 EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE------QLRQEREEQQLS 1573
Query: 286 SDEDGDDYIIDDFVVQDEEGDEENKNQQGEK 316
E + +++ V+ +E +E K + E+
Sbjct: 1574 RQERDRKFRLEEQKVRRQE--QERKFMEDEQ 1602
Score = 51.2 bits (121), Expect = 2e-06
Identities = 50/266 (18%), Positives = 116/266 (43%), Gaps = 27/266 (10%)
Query: 5 RRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDS---DEEL------ 55
RR E R P Q+ R + +R S+++ E+ D DEEL
Sbjct: 120 RRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQE 179
Query: 56 --DSDESFENDEELDSNKGPDCNKTPGSE--RELNLSKIQSEGNDSKCLINSGNGSTYEE 111
+ +E +E+L S KG + + P E R L +++ +G + K +
Sbjct: 180 WQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEK------------Q 227
Query: 112 ETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDD--QEKHLSQEDNDLNKQTGQIIE 169
+ + + + +++EK + + L K+ ++ E++ +++ L +E+ L K Q +
Sbjct: 228 QQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELR 287
Query: 170 DDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPE 229
+ +EE+ ++ + +R + +E R+ +R + E + EQ+
Sbjct: 288 RERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERR 347
Query: 230 KTLAAQKREKLQKLKELSKQRSRQRR 255
+ +++E+ ++ ++L +++ +RR
Sbjct: 348 EQQLRREQEEERREQQLRREQEEERR 373
Score = 48.5 bits (114), Expect = 2e-05
Identities = 67/333 (20%), Positives = 135/333 (40%), Gaps = 44/333 (13%)
Query: 4 VRRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDES-FE 62
+R E ++ + +PE++ + RR +R +L +EE + + ++L +E +
Sbjct: 798 LRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQ 857
Query: 63 NDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNID 122
D+E + +R + Q E + +E+ K +
Sbjct: 858 EDQE---------RRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL--- 905
Query: 123 LQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKR 182
LQ++E+ L +E+ + ++ Q + +E+ L QE+ L L EE KR ++
Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQL-----------LREEREKRRRQ 954
Query: 183 KRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREK--- 239
+R D + L+ + KR RR ++ E E + E+ L ++REK
Sbjct: 955 ERERQYRKDKKLQQKEEQLLGEEPEKR-RRQEREKKYREEEELQQEEEQLLREEREKRRR 1013
Query: 240 -------------LQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYES 286
Q+ ++L ++ +RR R+ + E+E +E EE +
Sbjct: 1014 QEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRR 1073
Query: 287 DEDGDDYIIDDFVVQDEE---GDEENKNQQGEK 316
E Y ++ + Q+EE +E K ++ E+
Sbjct: 1074 QELERQYRKEEELQQEEEQLLREEPEKRRRQER 1106
Score = 48.1 bits (113), Expect = 2e-05
Identities = 57/318 (17%), Positives = 129/318 (40%), Gaps = 37/318 (11%)
Query: 11 RNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEELDSN 70
R+ K + EQK R ++ + ++ +++L +E + D F DE+L
Sbjct: 1577 RDRKFRLEEQKVR------RQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQE 1630
Query: 71 KGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHL 130
+ +R+ + Q + + + + EE ++ ++Q+
Sbjct: 1631 REEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG----EEQQLRR 1686
Query: 131 SQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQT-------GQIIEDDLEEEDIKRGKRK 183
+ D ++ Q+ ++E+ QE+ L +Q + + + E+E ++R +R
Sbjct: 1687 QERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERY 1746
Query: 184 RLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQK-----RE 238
R + L R+ +R R+ E+E ++ Q+ E+ L +Q+ RE
Sbjct: 1747 RKILEEEQLRPEREEQQLRRQ---ERDRKFREEE----QLRQEREEQQLRSQESDRKFRE 1799
Query: 239 KLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDF 298
+ Q +E +Q+ R ++ G+ + E+ ++ +E + Y ++E F
Sbjct: 1800 EEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEE--------QF 1851
Query: 299 VVQDEEGDEENKNQQGEK 316
Q++ EE + Q E+
Sbjct: 1852 ATQEKSRREEQELWQEEE 1869
Score = 46.2 bits (108), Expect = 8e-05
Identities = 54/313 (17%), Positives = 137/313 (43%), Gaps = 39/313 (12%)
Query: 19 EQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEELDSNKGPDCNKT 78
E++ R+ RR +R + L +++L +E + D D F +E+ S + D K
Sbjct: 1378 EEEQRL--RRQERER--KFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERD-RKF 1432
Query: 79 PGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLN 138
E+++ + + + + + + + EE ++ R ++Q+ H + D
Sbjct: 1433 REEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER----EEQQLHRQERDRKFL 1488
Query: 139 KQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDS 198
++ Q+ ++++ +++ + + +E EE+ + R +R+R ++
Sbjct: 1489 EEEQQLRRQERDRKFREQELRSQEPERKFLE---EEQQLHRQQRQRKFL-------QEEQ 1538
Query: 199 DILVRKVGVKR----PRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQR 254
+ ++ G +R R+ E+E ++ Q+ E+ L+ Q+R++ +L+E +R Q
Sbjct: 1539 QLRRQERGQQRRQDRDRKFREEE----QLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE 1594
Query: 255 RSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQG 314
R + ED ++ + +E + + DE ++Q+ E + ++ ++
Sbjct: 1595 R---KFMEDEQQLRRQEGQQQLRQERDRKFREDEQ---------LLQEREEQQLHRQERD 1642
Query: 315 EKLTTSQLKLVKQ 327
K + +L +Q
Sbjct: 1643 RKFLEEEPQLRRQ 1655
Score = 46.2 bits (108), Expect = 8e-05
Identities = 61/334 (18%), Positives = 138/334 (41%), Gaps = 29/334 (8%)
Query: 14 KSHVPEQKSRVDWRRTKRSSISQ-LLDSDEELDSEEFDSDEELDSDESFENDEELDSNKG 72
+S PE+K + ++ R + L +++L +E D D F +E+L +
Sbjct: 1509 RSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQERE 1568
Query: 73 PDCNKTPGSERELNLS--KIQSEGNDSKCLINS-------GNGSTYEEETNKIKHRNIDL 123
+R+ L K++ + + K + + G +E K + L
Sbjct: 1569 EQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLL 1628
Query: 124 QDQEK---HLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRG 180
Q++E+ H + D ++ Q+ ++E+ L + + ++ Q++++ EE+ ++R
Sbjct: 1629 QEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG-EEQQLRRQ 1687
Query: 181 KRKRL--SSVMCDSDESDDSDILVRKVGVKRP---RRVVEDEGSSVEMEQKTPEKTLAAQ 235
+R R + + L + ++R R+ E+E E EQ+ + +
Sbjct: 1688 ERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYR 1747
Query: 236 KREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYII 295
K + ++L+ +++ +R+ R F + E ++ +E EE S E +
Sbjct: 1748 KILEEEQLRPEREEQQLRRQERDRKFREEE--------QLRQEREEQQLRSQESDRKFRE 1799
Query: 296 DDFVVQDEEGDEENKNQQGEKL--TTSQLKLVKQ 327
++ + Q+ E + Q+ K QL+L +Q
Sbjct: 1800 EEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQ 1833
Score = 43.1 bits (100), Expect = 6e-04
Identities = 55/326 (16%), Positives = 132/326 (40%), Gaps = 30/326 (9%)
Query: 5 RRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFEND 64
RR + R + EQ+ R + +R + + +EE ++ +++L ++ +
Sbjct: 334 RREQQLRREQEERREQQLRREQEEERREQQLRR-EQEEERREQQLRREQQLRREQQLRRE 392
Query: 65 EELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQ 124
++L + RE L + Q + + EEE ++ KH +
Sbjct: 393 QQL--------RREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE 444
Query: 125 DQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKR 184
+ K +E D K+ + +QE+ Q D ++ + LEEE+ + + +R
Sbjct: 445 QRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK-LEEEERREQQERR 503
Query: 185 LSSVMCDSDESDD-----------------SDILVRKVGVKRPRRVVEDEGSSVEMEQKT 227
+ + +E + S+ +R+ +R ++++ E +EQ+
Sbjct: 504 EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEK-RLEQER 562
Query: 228 PEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESD 287
E+ L ++ E+ +L + ++R +QR ++ ++ + +++EE +
Sbjct: 563 REQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKR 622
Query: 288 EDGDDYIIDDFVVQDEEGDEENKNQQ 313
E+ ++ + +E+ EE + QQ
Sbjct: 623 EEPEEERRQQLLKSEEQ--EERRQQQ 646
Score = 40.8 bits (94), Expect = 0.003
Identities = 77/420 (18%), Positives = 160/420 (38%), Gaps = 52/420 (12%)
Query: 4 VRRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFEN 63
++R E RR + EQ+ R++ +R KR + +L + +E + + E + +
Sbjct: 579 LKREEERRQQRLK-REQEERLE-QRLKREEVERL-EQEERREQRLKREEPEEERRQQLLK 635
Query: 64 DEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEET---------N 114
EE + + + RE L + + E + L E+E
Sbjct: 636 SEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARE 695
Query: 115 KIKHRNIDLQDQ-----EKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIE 169
+IK R Q Q + S+ + KQ GQ +QE+ + +++L Q +
Sbjct: 696 RIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAH 755
Query: 170 DDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPE 229
+EE+ +R + S+ +++ + P R + E Q
Sbjct: 756 RQQQEEEQRR-------DFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQ---- 804
Query: 230 KTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDED 289
Q+ ++ +E +QR RQRR ++ + E+E +++ E + +ED
Sbjct: 805 -----QREQRFLPEEEEKEQRRRQRREREKELQFLEEE-----EQLQRRERAQQLQEEED 854
Query: 290 GDDYIIDDFVVQDEEGDEENKNQQGEKLTTSQLKLVKQNSLYSFSDHYTHFERVVKALLI 349
G +Q+++ ++ Q+ ++ QL+ ++ ++ E++ K +
Sbjct: 855 G---------LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL 905
Query: 350 NALDESFLGTLYDGTRQKSYAKDMLTSLHYLDNRFVQPRLESLVSRSRWKEQYKERVENY 409
+E L R+K ++ Y + +Q E L+ R K + +ER Y
Sbjct: 906 LQEEEE---ELQREEREKRRRQEQ--ERQYREEEQLQQEEEQLLREEREKRRRQERERQY 960
Score = 39.3 bits (90), Expect = 0.009
Identities = 64/349 (18%), Positives = 137/349 (39%), Gaps = 41/349 (11%)
Query: 6 RHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFEND- 64
+ + RR + V +++ +WR KR ++ L +E+L EE EL +E
Sbjct: 226 KQQQRRERQDRVFQEEEEKEWR--KRETV--LRKEEEKLQEEEPQRQRELQEEEEQLRKL 281
Query: 65 --EELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNID 122
+EL + + + RE L + Q E + EE + + R
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQ----------QEERREQQERREQQ 331
Query: 123 LQDQEKHLSQEDNDLNKQT--GQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLE-EEDIKR 179
+ +E+ L +E + +Q + E+ +E+ L +E + ++ E L E+ ++R
Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR 391
Query: 180 GKRKRLSSVMCDSDESDDSDILVRKVGVKRP---RRVVEDEGSSVEMEQKTPEKTLAAQK 236
++ R + + L R+ ++R RR E+E + EQ+ E+ L ++
Sbjct: 392 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ 451
Query: 237 REKL------------------QKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEE 278
E+ Q+LK ++ R+R + E E++ E+
Sbjct: 452 EERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQ 511
Query: 279 EEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEKLTTSQLKLVKQ 327
EE ++ + + +++ E + ++ + L + K ++Q
Sbjct: 512 EERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQ 560
Score = 36.6 bits (83), Expect = 0.060
Identities = 42/196 (21%), Positives = 84/196 (42%), Gaps = 6/196 (3%)
Query: 136 DLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDES 195
D ++ Q + +++ L +E +Q Q E +L E + + K++RL D
Sbjct: 112 DRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQR--DRQRR 169
Query: 196 DDSDILVRKVGVKRPRRVVEDEG----SSVEMEQKTPEKTLAAQKREKLQKLKELSKQRS 251
D+ R+ +R R E+E E E+ E+ L ++ +L++ KQ+
Sbjct: 170 DEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQ 229
Query: 252 RQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKN 311
R+ R E+ EKE + +EEE+ E + + ++ ++ E E +
Sbjct: 230 RRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRE 289
Query: 312 QQGEKLTTSQLKLVKQ 327
+Q E+ +L+ +Q
Sbjct: 290 RQEEEQQQQRLRREQQ 305
Score = 32.3 bits (72), Expect = 1.1
Identities = 28/117 (23%), Positives = 56/117 (47%), Gaps = 10/117 (8%)
Query: 172 LEEEDIKRGKRKRLSSVMCDSDESDDSDI-------LVRKVGVKRPRRVVEDEGSSVEME 224
L+EE KR + S++ D + +D L + G +R ++ E E E E
Sbjct: 95 LDEE--KRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGE 152
Query: 225 QKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEE 281
+++ EK ++R++ ++ +EL +QR + R E+ + +SC + + +EE
Sbjct: 153 EQS-EKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEE 208
>gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]
Length = 1726
Score = 55.8 bits (133), Expect = 1e-07
Identities = 59/234 (25%), Positives = 98/234 (41%), Gaps = 40/234 (17%)
Query: 110 EEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIE 169
E++ + + N+D QD++ +L ND +DD+++ E +D
Sbjct: 34 EDDDEEEEEENLDDQDEQGNLKGFIND---------DDDEDEGEEDEGSDSGD------- 77
Query: 170 DDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPE 229
E+D+ KRKR S D E DD D++ +GVK R + ++ E
Sbjct: 78 ---SEDDVGHKKRKRTS--FDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMSDDEDDDE 132
Query: 230 KTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDED 289
+ ++ EK +E+ + G E E P + EEEEED+ ESD
Sbjct: 133 EEYGKEEHEKEAIAEEIFQ--------DGEGEEGQEAMEAPMAP--PEEEEEDDEESD-- 180
Query: 290 GDDYIIDDFVVQDEEGDEENKNQQGEKLT-TSQLKLVKQNSLYSFSDHYTHFER 342
IDDF+V D++G K + +KL + L + ++ Y FE+
Sbjct: 181 -----IDDFIV-DDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEK 228
Score = 44.7 bits (104), Expect = 2e-04
Identities = 63/265 (23%), Positives = 111/265 (41%), Gaps = 68/265 (25%)
Query: 39 DSDEELDSEEFDSDEELDSDESFENDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSK 98
D DEE + E D +E + + F ND++ D ++G + EG+DS
Sbjct: 35 DDDEEEEEENLDDQDEQGNLKGFINDDD-DEDEGE-----------------EDEGSDS- 75
Query: 99 CLINSGNGSTYEEETNKIKHR---NIDLQDQEKHLSQEDNDLNKQTGQII---------E 146
G + ++ +K + R + L+D + L +E+ + + GQ E
Sbjct: 76 -------GDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMSDDE 128
Query: 147 DDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVG 206
DD E+ +E+++ +I +D E E+ + ++ + ++ ++SDI
Sbjct: 129 DDDEEEYGKEEHEKEAIAEEIFQDG-EGEEGQEAMEAPMAPPEEEEEDDEESDI------ 181
Query: 207 VKRPRRVVEDEGSSV---EMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFED 263
+V+D+G + + +K P T AA LQ+ +E+ G DF+
Sbjct: 182 ---DDFIVDDDGQPLKKPKWRKKLPGYTDAA-----LQEAQEI----------FGVDFDY 223
Query: 264 SEKESCPSSDEVDEEEEEDNYESDE 288
E E DE E EEE YE DE
Sbjct: 224 DEFEKYNEYDE--ELEEEYEYEDDE 246
Score = 30.0 bits (66), Expect = 5.7
Identities = 17/52 (32%), Positives = 30/52 (57%), Gaps = 4/52 (7%)
Query: 266 KESCPSSDEVDEEEEEDNYESDEDGD--DYIIDDFVVQDEEGDEENKNQQGE 315
K+ D+ +EEEEE+ + DE G+ +I DD ++EG+E+ + G+
Sbjct: 28 KKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDD--DDEDEGEEDEGSDSGD 77
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 55.5 bits (132), Expect = 1e-07
Identities = 70/307 (22%), Positives = 129/307 (42%), Gaps = 62/307 (20%)
Query: 10 RRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEE----------FDSDEELDSDE 59
+R S S P + +++ ++ +L + +L EE F + L ++
Sbjct: 2062 KRESLSKEPAKLNKI------LKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQ 2115
Query: 60 SFENDEELD-SNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKH 118
S + +E D S K + K E++L K + N + +IN T EE KH
Sbjct: 2116 SKLDIKEWDFSEKRSELTK---DEKKL-ARKQRKLANKMRRMINKEEKMTEEESKLARKH 2171
Query: 119 RNIDLQDQE--------------------KHLSQEDNDLNKQTGQIIEDDQEKHLSQEDN 158
+ L D+E K + D K + Q+ E + E+H S+E
Sbjct: 2172 SEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEME 2231
Query: 159 DLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEG 218
L D+LE K++ LSS + + ++ + +V + R E+EG
Sbjct: 2232 SLL--------DELE-------KQESLSSEE-EEEREEEEEREEEEVREEEEERKEEEEG 2275
Query: 219 SS--VEMEQKTPEKTLAAQKREKLQKLKELSKQRSR---QRRSSGRDFEDSEKESCPSSD 273
VE E++ +K +K+E++Q+ +E+ +++ + + E+ E+ESC +
Sbjct: 2276 EEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEE 2335
Query: 274 EVDEEEE 280
EVD E+E
Sbjct: 2336 EVDREKE 2342
Score = 49.3 bits (116), Expect = 9e-06
Identities = 50/231 (21%), Positives = 109/231 (47%), Gaps = 31/231 (13%)
Query: 122 DLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDD-----LEEED 176
+L EK L+++ L + ++I ++E+ +++E++ L ++ ++I DD +EEE+
Sbjct: 2131 ELTKDEKKLARKQRKLANKMRRMI--NKEEKMTEEESKLARKHSEVILDDEEEGGIEEEE 2188
Query: 177 I----KRGKRKRLSSVMCDS---------DESDDSDILVRKVG-----VKRPRRVVEDEG 218
+ KR RKR + D DE + + ++ +++ + +E
Sbjct: 2189 VIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEE 2248
Query: 219 SSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEE 278
E E++ E+ + ++ E+ ++ + KQ ++ + ++ +KE +EV EE
Sbjct: 2249 EEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEE 2308
Query: 279 EEE--DNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEKLTTSQLKLVKQ 327
+EE E++ D+ ++ +EE D E + + EK Q KL +Q
Sbjct: 2309 KEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEK----QFKLQEQ 2355
Score = 44.7 bits (104), Expect = 2e-04
Identities = 63/321 (19%), Positives = 129/321 (40%), Gaps = 42/321 (13%)
Query: 8 ETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEEL 67
ETR++ K+ E + R+ K + L +EE+ E D++L +E + E +
Sbjct: 1473 ETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQE----DKKLKWEEWKQVWENM 1528
Query: 68 DSNKGPDCNKTPGSERELNLSK-IQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQ 126
S+K + + E E+ L + + EG + + + EE HR
Sbjct: 1529 LSSKSKE--QQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRK--RARA 1584
Query: 127 EKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLS 186
EK +QE+ L ++ ++ ++ E+ L+QE+ L + +I +DD
Sbjct: 1585 EKKRAQEERKLAQEEEKLAQE--ERQLAQEERKLAQAYVKITQDD--------------- 1627
Query: 187 SVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKEL 246
R++ + ++E + E+ + E AQKR+KL K E
Sbjct: 1628 ----------------REMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEK 1671
Query: 247 SKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGD 306
+ + G + + +E+ + E+ +++ E + ++ +++
Sbjct: 1672 VAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWK 1731
Query: 307 EENKNQQGEKLTTSQLKLVKQ 327
EE NQ+ KL + KL ++
Sbjct: 1732 EEELNQEEGKLVEEKKKLAEE 1752
Score = 43.5 bits (101), Expect = 5e-04
Identities = 51/283 (18%), Positives = 118/283 (41%), Gaps = 39/283 (13%)
Query: 7 HETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEF-----------DSDEEL 55
H+ R + +K R R +L + +L EE D E
Sbjct: 1572 HKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMA 1631
Query: 56 DSDESFENDEELDSNKGPDCNKTP---GSERELNLSKIQSEGNDSKCLINSGNG-----S 107
++ F EE + +G ++ +R+ K + + + L G +
Sbjct: 1632 QAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKN 1691
Query: 108 TYEEETNKIKHRNIDLQDQEKHLSQE--------------DNDLNKQTGQIIEDDQEKHL 153
++ ++ R +L QEK L+QE + +LN++ G+++E+ +K L
Sbjct: 1692 ILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEE--KKKL 1749
Query: 154 SQEDNDLNKQTGQIIEDDL---EEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRP 210
++E+ L Q ++ E++ +EE++ ++++L+ E ++ R+ +++
Sbjct: 1750 AEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKK 1809
Query: 211 RRVVEDEGSSVE-MEQKTPEKTLAAQKREKLQKLKELSKQRSR 252
++ + + ME+ T K + QK+ Q+ K L++++ +
Sbjct: 1810 MKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEK 1852
Score = 35.4 bits (80), Expect = 0.13
Identities = 52/247 (21%), Positives = 106/247 (42%), Gaps = 27/247 (10%)
Query: 19 EQKSRVDWRRTKRSSISQLLDSDEELDSEEFD-----SDEELDSDESFENDEELDSNKGP 73
++K +R + + ++++ +E++ EE S+ LD +E +EE
Sbjct: 2135 DEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEE------- 2187
Query: 74 DCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEE--TNKIKHRNIDLQDQEKHLS 131
P +R K G+ K +S EE + +++ +L+ QE S
Sbjct: 2188 --EVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSS 2245
Query: 132 QEDNDLNKQTGQIIED--DQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVM 189
+E+ + ++ + E+ ++E+ +E+ KQ + EEE K+ K K+ V
Sbjct: 2246 EEEEEREEEEEREEEEVREEEEERKEEEEGEEKQV-----EKEEEEKKKKKKEKKKEEVQ 2300
Query: 190 CDSDE--SDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELS 247
+ +E + +I+ + E+E S+E E ++ L +K+ KLQ+ + S
Sbjct: 2301 -EKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKS 2359
Query: 248 KQRSRQR 254
R R+R
Sbjct: 2360 -LRGRER 2365
Score = 32.7 bits (73), Expect = 0.87
Identities = 41/187 (21%), Positives = 78/187 (41%), Gaps = 39/187 (20%)
Query: 5 RRHETRRNSK------SHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSD 58
+R E +R K S V E +S + S + +L + EE + +EE + +
Sbjct: 2199 KRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEERE 2258
Query: 59 ESFENDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKH 118
E +EE ER K + EG + + EEE K K
Sbjct: 2259 EEEVREEE--------------EER-----KEEEEGEEKQV-------EKEEEEKKKKK- 2291
Query: 119 RNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIK 178
++++K QE ++ ++ +I+ +++ + LS E+ + + E D E+E +K
Sbjct: 2292 -----KEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEE-EESCSLEEEVDREKEILK 2345
Query: 179 RGKRKRL 185
+ K+ +L
Sbjct: 2346 KEKQFKL 2352
Score = 30.4 bits (67), Expect = 4.3
Identities = 30/144 (20%), Positives = 65/144 (45%), Gaps = 7/144 (4%)
Query: 137 LNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLE---EEDIKRGKRKRLSSVMCDSD 193
L K++ ++ED + E + Q G I ED ++ +E I+ +
Sbjct: 1294 LKKESKVLLEDLDWDVVPPEKKPIFIQEGAIREDMIQGVTQEVIRHKEVMPREEEQAQKK 1353
Query: 194 ESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQ 253
D + +V +K+ ++V+ E +V M ++ +K ++++ QK + ++ ++
Sbjct: 1354 ARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKK----EEKKTFQKSPKQGRKAVQK 1409
Query: 254 RRSSGRDFEDSEKESCPSSDEVDE 277
R G+ + KE S+EV+E
Sbjct: 1410 ERKVGKIKREMTKEERDMSEEVEE 1433
>gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]
Length = 538
Score = 55.5 bits (132), Expect = 1e-07
Identities = 51/243 (20%), Positives = 108/243 (44%), Gaps = 15/243 (6%)
Query: 83 RELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTG 142
REL K + +++ + N EE + + R + + QE+ L + T
Sbjct: 8 RELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRR---ARQERLRQKQEEESLGQVTD 64
Query: 143 QIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEE--EDIKRGKRKRLSSVMCDSDESDDSDI 200
Q+ E + + + E+ Q+ DD E + R + +R + + + D
Sbjct: 65 QV-EVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDP 123
Query: 201 LVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRD 260
+ + P R ++++ + E +T EK ++ R++ +++E +++ RD
Sbjct: 124 TITDASLSLPSRRMQNDTA----ENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRD 179
Query: 261 FEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEKLTTS 320
E+++KE D+ EEEEE+ + G++ I D+ + +D+E EE K+ K +
Sbjct: 180 AEENKKE-----DKEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPKEEVKSFMDRKKGFT 234
Query: 321 QLK 323
++K
Sbjct: 235 EVK 237
Score = 38.5 bits (88), Expect = 0.016
Identities = 63/301 (20%), Positives = 118/301 (39%), Gaps = 35/301 (11%)
Query: 5 RRHETRRNSKSHVPEQKSRVDWRRTKRS-SISQLLDSDEELDSEEFDSDEELDS-DESFE 62
RR E R+ E++ D T S S+ ++ ++E + +E+ +S E +E
Sbjct: 102 RREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYE 161
Query: 63 NDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNID 122
+E K N +E K + E + K GS E N+IK I
Sbjct: 162 IEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEK----PKRGSIGE---NQIKDEKIK 214
Query: 123 LQDQEKHLSQEDNDLNKQTGQIIEDDQE---KHLSQEDNDLNKQTGQIIEDDLEEE---D 176
+ K + D K ++ + E L +N ++ G+ D E E
Sbjct: 215 KDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQ 274
Query: 177 IKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQK 236
++ GKR ES++ + L +K + +++E+E+ +K
Sbjct: 275 VEAGKRLEELRRRRGETESEEFEKLKQK-----------QQEAALELEE-------LKKK 316
Query: 237 REKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIID 296
RE+ +K+ E +QR +Q + + E+ EK +E++ E + + +D + D
Sbjct: 317 REERRKVLEEEEQRRKQEEADRKLREEEEKRRL--KEEIERRRAEAAEKRQKMPEDGLSD 374
Query: 297 D 297
D
Sbjct: 375 D 375
>gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]
Length = 532
Score = 55.1 bits (131), Expect = 2e-07
Identities = 45/216 (20%), Positives = 98/216 (45%), Gaps = 12/216 (5%)
Query: 110 EEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIE 169
++E + R + + QE+ L + T Q+ E + + + E+ Q+
Sbjct: 26 DDEEEAARERRRRARQERLRQKQEEESLGQVTDQV-EVNAQNSVPDEEAKTTTTNTQVEG 84
Query: 170 DDLEE--EDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKT 227
DD E + R + +R + + + D + + P R ++++ + E +T
Sbjct: 85 DDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTA----ENET 140
Query: 228 PEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESD 287
EK ++ R++ +++E +++ RD E+++KE D+ EEEEE+ +
Sbjct: 141 TEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKE-----DKEKEEEEEEKPKRG 195
Query: 288 EDGDDYIIDDFVVQDEEGDEENKNQQGEKLTTSQLK 323
G++ I D+ + +D+E EE K+ K +++K
Sbjct: 196 SIGENQIKDEKIKKDKEPKEEVKSFMDRKKGFTEVK 231
Score = 38.5 bits (88), Expect = 0.016
Identities = 63/301 (20%), Positives = 118/301 (39%), Gaps = 35/301 (11%)
Query: 5 RRHETRRNSKSHVPEQKSRVDWRRTKRS-SISQLLDSDEELDSEEFDSDEELDS-DESFE 62
RR E R+ E++ D T S S+ ++ ++E + +E+ +S E +E
Sbjct: 96 RREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYE 155
Query: 63 NDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNID 122
+E K N +E K + E + K GS E N+IK I
Sbjct: 156 IEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEK----PKRGSIGE---NQIKDEKIK 208
Query: 123 LQDQEKHLSQEDNDLNKQTGQIIEDDQE---KHLSQEDNDLNKQTGQIIEDDLEEE---D 176
+ K + D K ++ + E L +N ++ G+ D E E
Sbjct: 209 KDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQ 268
Query: 177 IKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQK 236
++ GKR ES++ + L +K + +++E+E+ +K
Sbjct: 269 VEAGKRLEELRRRRGETESEEFEKLKQK-----------QQEAALELEE-------LKKK 310
Query: 237 REKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIID 296
RE+ +K+ E +QR +Q + + E+ EK +E++ E + + +D + D
Sbjct: 311 REERRKVLEEEEQRRKQEEADRKLREEEEKRRL--KEEIERRRAEAAEKRQKMPEDGLSD 368
Query: 297 D 297
D
Sbjct: 369 D 369
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 53.1 bits (126), Expect = 6e-07
Identities = 60/301 (19%), Positives = 122/301 (40%), Gaps = 20/301 (6%)
Query: 5 RRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFEND 64
RR R + ++ R R +R + + + E D + D +E D D E D
Sbjct: 309 RRERERERERERERREREREREREREREKEKER-ERERERDRDR-DRTKERDRDRDRERD 366
Query: 65 EELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQ 124
+ D + D NK RE + + + + + E E + + R + +
Sbjct: 367 RDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERERE 426
Query: 125 DQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLN------KQTGQIIEDDLEEEDIK 178
+K +ED + + ++ +EK + ++ N K+T + ++ EE+ +
Sbjct: 427 KDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERR 486
Query: 179 RG---KRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQ 235
R + KRL + D D+ D R +++ R E E + E ++K ++ L
Sbjct: 487 REMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEI 546
Query: 236 KREKLQK--------LKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESD 287
++ L + L+ + ++ R+R+ + +SE+E E +E+ EE E +
Sbjct: 547 RQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEE-EEKQEKEEKREEPMEEEE 605
Query: 288 E 288
E
Sbjct: 606 E 606
Score = 44.3 bits (103), Expect = 3e-04
Identities = 41/182 (22%), Positives = 75/182 (41%), Gaps = 5/182 (2%)
Query: 105 NGSTYEEETNKIKHRNID-LQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQ 163
N EE+ + R I +D K L +E K+ +I ++ +E+ +E ++
Sbjct: 265 NAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRE 324
Query: 164 TGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEM 223
+ E + E E K +R+R D + D D R+ R R D
Sbjct: 325 REREREREREREKEKERERERERDRDRDRTKERDRD-RDRERDRDRDRERSSDRNKD--- 380
Query: 224 EQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDN 283
++ EK+ ++ + ++ +E ++R R+R + E+E EE+EED
Sbjct: 381 RSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDA 440
Query: 284 YE 285
YE
Sbjct: 441 YE 442
Score = 39.7 bits (91), Expect = 0.007
Identities = 28/126 (22%), Positives = 58/126 (46%), Gaps = 3/126 (2%)
Query: 194 ESDDSDILVRKVGVKRP-RRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKL--KELSKQR 250
E D D++ R++ R + +E+E E E++ EK ++RE+ ++ +E ++R
Sbjct: 270 EEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERER 329
Query: 251 SRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENK 310
R+R + E+E D E + + + E D D D D E+++
Sbjct: 330 EREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSR 389
Query: 311 NQQGEK 316
+++ E+
Sbjct: 390 DRERER 395
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 53.1 bits (126), Expect = 6e-07
Identities = 75/349 (21%), Positives = 145/349 (41%), Gaps = 43/349 (12%)
Query: 5 RRHETRRNSKSHVPEQKSRVDWRR-TKR------SSISQLLDSDEELDSEEFDSDEE--- 54
++ T K+ + ++K R R TKR SS S ++ D++ E SDE+
Sbjct: 1130 KKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIK 1189
Query: 55 -------LDSDESF---ENDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSG 104
L S F DE L + + N + + K ++S
Sbjct: 1190 PVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSD 1249
Query: 105 NGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQE--DNDLNK 162
+ ++E + K R ++ + N +N ++ E+ ++ + L
Sbjct: 1250 EDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTV 1309
Query: 163 QTGQIIEDDL----EEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEG 218
G+ E+ E +++K R+++SS ++S+DSD V +E
Sbjct: 1310 SDGESGEEKKTKPKEHKEVKGRNRRKVSS-----EDSEDSDF---------QESGVSEEV 1355
Query: 219 SSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEE 278
S E EQ+ +T +A+K E L++ + KQ+ ++RR ++ SE +S +E ++E
Sbjct: 1356 SESEDEQRP--RTRSAKKAE-LEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKE 1412
Query: 279 EEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEKLTTSQLKLVKQ 327
EEE+ E +E+ ++ DD + + K + +KL T +K+
Sbjct: 1413 EEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKE 1461
Score = 52.0 bits (123), Expect = 1e-06
Identities = 52/264 (19%), Positives = 106/264 (40%), Gaps = 33/264 (12%)
Query: 55 LDSDESFENDEELDSNK---GPDCNKTPGSERELNL--SKIQSEGNDSKC---------- 99
L SDE +D+E + K G + PG E N S+ S+ +SK
Sbjct: 1246 LSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRH 1305
Query: 100 -LINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDN 158
L S S E++T +H+ + +++ K S++ D + Q + E+ E Q
Sbjct: 1306 KLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPR 1365
Query: 159 DLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEG 218
+ + ++ E+ + K+ +R ++ ++S+ + K + E+E
Sbjct: 1366 TRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEE 1425
Query: 219 SSVEMEQKTPEK-----------------TLAAQKREKLQKLKELSKQRSRQRRSSGRDF 261
+ K+P K T A K E+ ++ + ++R R++ +
Sbjct: 1426 EDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEI 1485
Query: 262 EDSEKESCPSSDEVDEEEEEDNYE 285
ED+ CP + ++ +E+E+ E
Sbjct: 1486 EDASPTKCPITTKLVLDEDEETKE 1509
Score = 45.8 bits (107), Expect = 1e-04
Identities = 41/150 (27%), Positives = 67/150 (44%), Gaps = 9/150 (6%)
Query: 5 RRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFEND 64
+R TR K+ + E+ R ++ KR I DS E S + +EE + +E E +
Sbjct: 1362 QRPRTRSAKKAEL-EENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEE 1420
Query: 65 EELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNK-IKHRNIDL 123
EE + D +K+PG R+ KI+ D K + N EEE K I R +
Sbjct: 1421 EEEEEEDENDDSKSPGKGRK----KIRKILKDDKLRTETQNALKEEEERRKRIAERERER 1476
Query: 124 QDQEKHLSQEDNDLNK---QTGQIIEDDQE 150
+ + + ED K T ++++D+E
Sbjct: 1477 EKLREVIEIEDASPTKCPITTKLVLDEDEE 1506
Score = 40.8 bits (94), Expect = 0.003
Identities = 75/358 (20%), Positives = 132/358 (36%), Gaps = 49/358 (13%)
Query: 2 IHVRRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDE------ELDSEEFDSDEEL 55
+ VR+ + R +S S + K + + ++ Q DSDE E+ S +
Sbjct: 655 VPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDT 714
Query: 56 DSDESFENDEEL----------DSNKGPDCNKTPGSERELNLSK-IQSEGNDSKCLINSG 104
D +E N + L D K + T GS+ + K +S K
Sbjct: 715 DINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQS 774
Query: 105 NGSTYEEETNK-IKH-----------------RNIDLQDQEKHLSQEDNDLNKQTGQIIE 146
S Y+ E K IK ++ D + EKH ++ Q + ++
Sbjct: 775 ESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKH---SKKGMDNQGHKNLK 831
Query: 147 DDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRK-- 204
QE + ++T E ++++ R RL S +D D L K
Sbjct: 832 TSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQ 891
Query: 205 -VGVKRPRRVVEDEGSSVEMEQKTPEKTL--AAQKREKLQKLKELSKQRSRQRRSSGRDF 261
R+V E + S ++ KT +K + EK K + + ++ S +
Sbjct: 892 SFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGT 951
Query: 262 EDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIID-DFVVQDEEGDEENKN--QQGEK 316
E+ +K PS + + E YES DG + + + + + +G ++ KN GEK
Sbjct: 952 EEKKK---PSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEK 1006
Score = 34.7 bits (78), Expect = 0.23
Identities = 76/358 (21%), Positives = 132/358 (36%), Gaps = 81/358 (22%)
Query: 9 TRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSD--EELDSEEFDSDEELDSD-------- 58
+R+ S Q + +RT +S+ + SD EE E ++ E+LD D
Sbjct: 427 SRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSV 486
Query: 59 -----ESFENDEELDSNKGPDCNKTPGSERELNLS--KIQSEGNDSKCLINSGNGSTYEE 111
E+ E E+ S+ + + G+E+E+ S K+ D++ I S + +
Sbjct: 487 PEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTK 546
Query: 112 ET----NKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEK-HLSQEDNDLNKQTGQ 166
E + N ++ + +D D K G + EK L QE++D
Sbjct: 547 ELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCG--LNPKLEKCGLGQENSDNEHLVEN 604
Query: 167 IIEDDLEEEDIKRGKRKRLSS---------VMCDSDESDDSDILVR-KVGV---KRPRRV 213
+ LEE D++R R + + V +SDE + + + K+ V K+ +R
Sbjct: 605 EVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRN 664
Query: 214 VEDEGSSVEMEQKTPEKTLA------AQKREKLQKLKELSK------------------- 248
D K P+ + + E L LKE+S+
Sbjct: 665 SSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHK 724
Query: 249 ---------------QRSRQRRSSGRDFE----DSEKESCPSSDEVDEEEEEDNYESD 287
+R R+ +SG DF+ S K S S + + E NY+S+
Sbjct: 725 TLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSE 782
Score = 33.5 bits (75), Expect = 0.51
Identities = 49/267 (18%), Positives = 112/267 (41%), Gaps = 25/267 (9%)
Query: 28 RTKRSSISQLLDSDEELDSE---------EFDSDEELDSDESFENDE-ELDSNKGPDCNK 77
+ KR + S+ + D EL+ E + + + + + F++ E E S KG D
Sbjct: 767 KKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQG 826
Query: 78 TPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDL 137
+ S +E + +S G T +++T ++ R+ + Q+ S + D
Sbjct: 827 HKNLKTSQEGSSDDAERKQERETFSSAEG-TVDKDTTIMELRDRLPKKQQASASTDGVDK 885
Query: 138 ---NKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDE 194
+Q+ +E + ++ L +T + ++D L + K K+ + SDE
Sbjct: 886 LSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQ-------SDE 938
Query: 195 SDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQR 254
+ + D K G + ++ + + ++MEQ+ + +K + +++ K + +
Sbjct: 939 TSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIK 998
Query: 255 RSSGRDFEDSEKESCPSSDEVDEEEEE 281
+ D EK+S D+ ++++E
Sbjct: 999 NGT----TDGEKKSKKIRDKTSKKKDE 1021
Score = 32.7 bits (73), Expect = 0.87
Identities = 72/372 (19%), Positives = 145/372 (38%), Gaps = 69/372 (18%)
Query: 11 RNSKSHVPEQK---SRVDWRRTKRSSISQ---LLDSDEELDSEEFDSDEELDSDESFEND 64
R +K +P K S D + +K+ +Q L + +E S++ + +E ++ S E
Sbjct: 797 RTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGT 856
Query: 65 EELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNI-DL 123
+ D+ ++ P ++ + ++G D S E+ ++ R + +
Sbjct: 857 VDKDTTIMELRDRLPKKQQ----ASASTDGVDKL--------SGKEQSFTSLEVRKVAET 904
Query: 124 QDQEKHLSQE-----DNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIK 178
+++ KHL + + L+ + ++ DQ S++D KQ+ + E+ + D K
Sbjct: 905 KEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDK---KQSKKGTEEKKKPSDFK 961
Query: 179 RGKRKRLSSVMCDSDESD-----------------------DSDILVRKVGVKRPRRVVE 215
+ K SD ++ D + +K+ K ++ E
Sbjct: 962 KKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDE 1021
Query: 216 ---------DEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEK 266
+G S + + K A + +K KL S ++ + SS + ++
Sbjct: 1022 LSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKE 1081
Query: 267 ESCPSSD---EVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEKLTTSQLK 323
+ C SSD + E E N S + + EE E+NK + ++ T+S+ K
Sbjct: 1082 DGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKK--KQRTSSKKK 1139
Query: 324 LV-----KQNSL 330
V K+NSL
Sbjct: 1140 AVIVKEKKRNSL 1151
Score = 30.4 bits (67), Expect = 4.3
Identities = 19/105 (18%), Positives = 47/105 (44%), Gaps = 5/105 (4%)
Query: 183 KRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQK 242
++L + S E + ++ + + + GS+ +M + + E+ ++ +K
Sbjct: 16 QKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSS-----EK 70
Query: 243 LKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESD 287
K RS+++ S + +S+ E + V+E+ +N E+D
Sbjct: 71 SKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSEND 115
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 53.1 bits (126), Expect = 6e-07
Identities = 75/349 (21%), Positives = 145/349 (41%), Gaps = 43/349 (12%)
Query: 5 RRHETRRNSKSHVPEQKSRVDWRR-TKR------SSISQLLDSDEELDSEEFDSDEE--- 54
++ T K+ + ++K R R TKR SS S ++ D++ E SDE+
Sbjct: 1168 KKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIK 1227
Query: 55 -------LDSDESF---ENDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSG 104
L S F DE L + + N + + K ++S
Sbjct: 1228 PVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSD 1287
Query: 105 NGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQE--DNDLNK 162
+ ++E + K R ++ + N +N ++ E+ ++ + L
Sbjct: 1288 EDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTV 1347
Query: 163 QTGQIIEDDL----EEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEG 218
G+ E+ E +++K R+++SS ++S+DSD V +E
Sbjct: 1348 SDGESGEEKKTKPKEHKEVKGRNRRKVSS-----EDSEDSDF---------QESGVSEEV 1393
Query: 219 SSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEE 278
S E EQ+ +T +A+K E L++ + KQ+ ++RR ++ SE +S +E ++E
Sbjct: 1394 SESEDEQRP--RTRSAKKAE-LEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKE 1450
Query: 279 EEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEKLTTSQLKLVKQ 327
EEE+ E +E+ ++ DD + + K + +KL T +K+
Sbjct: 1451 EEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKE 1499
Score = 52.0 bits (123), Expect = 1e-06
Identities = 52/264 (19%), Positives = 106/264 (40%), Gaps = 33/264 (12%)
Query: 55 LDSDESFENDEELDSNK---GPDCNKTPGSERELNL--SKIQSEGNDSKC---------- 99
L SDE +D+E + K G + PG E N S+ S+ +SK
Sbjct: 1284 LSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRH 1343
Query: 100 -LINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDN 158
L S S E++T +H+ + +++ K S++ D + Q + E+ E Q
Sbjct: 1344 KLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPR 1403
Query: 159 DLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEG 218
+ + ++ E+ + K+ +R ++ ++S+ + K + E+E
Sbjct: 1404 TRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEE 1463
Query: 219 SSVEMEQKTPEK-----------------TLAAQKREKLQKLKELSKQRSRQRRSSGRDF 261
+ K+P K T A K E+ ++ + ++R R++ +
Sbjct: 1464 EDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEI 1523
Query: 262 EDSEKESCPSSDEVDEEEEEDNYE 285
ED+ CP + ++ +E+E+ E
Sbjct: 1524 EDASPTKCPITTKLVLDEDEETKE 1547
Score = 45.8 bits (107), Expect = 1e-04
Identities = 41/150 (27%), Positives = 67/150 (44%), Gaps = 9/150 (6%)
Query: 5 RRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFEND 64
+R TR K+ + E+ R ++ KR I DS E S + +EE + +E E +
Sbjct: 1400 QRPRTRSAKKAEL-EENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEE 1458
Query: 65 EELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNK-IKHRNIDL 123
EE + D +K+PG R+ KI+ D K + N EEE K I R +
Sbjct: 1459 EEEEEEDENDDSKSPGKGRK----KIRKILKDDKLRTETQNALKEEEERRKRIAERERER 1514
Query: 124 QDQEKHLSQEDNDLNK---QTGQIIEDDQE 150
+ + + ED K T ++++D+E
Sbjct: 1515 EKLREVIEIEDASPTKCPITTKLVLDEDEE 1544
Score = 40.8 bits (94), Expect = 0.003
Identities = 75/358 (20%), Positives = 132/358 (36%), Gaps = 49/358 (13%)
Query: 2 IHVRRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDE------ELDSEEFDSDEEL 55
+ VR+ + R +S S + K + + ++ Q DSDE E+ S +
Sbjct: 693 VPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDT 752
Query: 56 DSDESFENDEEL----------DSNKGPDCNKTPGSERELNLSK-IQSEGNDSKCLINSG 104
D +E N + L D K + T GS+ + K +S K
Sbjct: 753 DINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQS 812
Query: 105 NGSTYEEETNK-IKH-----------------RNIDLQDQEKHLSQEDNDLNKQTGQIIE 146
S Y+ E K IK ++ D + EKH ++ Q + ++
Sbjct: 813 ESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKH---SKKGMDNQGHKNLK 869
Query: 147 DDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRK-- 204
QE + ++T E ++++ R RL S +D D L K
Sbjct: 870 TSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQ 929
Query: 205 -VGVKRPRRVVEDEGSSVEMEQKTPEKTL--AAQKREKLQKLKELSKQRSRQRRSSGRDF 261
R+V E + S ++ KT +K + EK K + + ++ S +
Sbjct: 930 SFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGT 989
Query: 262 EDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIID-DFVVQDEEGDEENKN--QQGEK 316
E+ +K PS + + E YES DG + + + + + +G ++ KN GEK
Sbjct: 990 EEKKK---PSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEK 1044
Score = 34.7 bits (78), Expect = 0.23
Identities = 76/358 (21%), Positives = 132/358 (36%), Gaps = 81/358 (22%)
Query: 9 TRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSD--EELDSEEFDSDEELDSD-------- 58
+R+ S Q + +RT +S+ + SD EE E ++ E+LD D
Sbjct: 465 SRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSV 524
Query: 59 -----ESFENDEELDSNKGPDCNKTPGSERELNLS--KIQSEGNDSKCLINSGNGSTYEE 111
E+ E E+ S+ + + G+E+E+ S K+ D++ I S + +
Sbjct: 525 PEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTK 584
Query: 112 ET----NKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEK-HLSQEDNDLNKQTGQ 166
E + N ++ + +D D K G + EK L QE++D
Sbjct: 585 ELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCG--LNPKLEKCGLGQENSDNEHLVEN 642
Query: 167 IIEDDLEEEDIKRGKRKRLSS---------VMCDSDESDDSDILVR-KVGV---KRPRRV 213
+ LEE D++R R + + V +SDE + + + K+ V K+ +R
Sbjct: 643 EVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRN 702
Query: 214 VEDEGSSVEMEQKTPEKTLA------AQKREKLQKLKELSK------------------- 248
D K P+ + + E L LKE+S+
Sbjct: 703 SSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHK 762
Query: 249 ---------------QRSRQRRSSGRDFE----DSEKESCPSSDEVDEEEEEDNYESD 287
+R R+ +SG DF+ S K S S + + E NY+S+
Sbjct: 763 TLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSE 820
Score = 33.5 bits (75), Expect = 0.51
Identities = 49/267 (18%), Positives = 112/267 (41%), Gaps = 25/267 (9%)
Query: 28 RTKRSSISQLLDSDEELDSE---------EFDSDEELDSDESFENDE-ELDSNKGPDCNK 77
+ KR + S+ + D EL+ E + + + + + F++ E E S KG D
Sbjct: 805 KKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQG 864
Query: 78 TPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDL 137
+ S +E + +S G T +++T ++ R+ + Q+ S + D
Sbjct: 865 HKNLKTSQEGSSDDAERKQERETFSSAEG-TVDKDTTIMELRDRLPKKQQASASTDGVDK 923
Query: 138 ---NKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDE 194
+Q+ +E + ++ L +T + ++D L + K K+ + SDE
Sbjct: 924 LSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQ-------SDE 976
Query: 195 SDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQR 254
+ + D K G + ++ + + ++MEQ+ + +K + +++ K + +
Sbjct: 977 TSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIK 1036
Query: 255 RSSGRDFEDSEKESCPSSDEVDEEEEE 281
+ D EK+S D+ ++++E
Sbjct: 1037 NGT----TDGEKKSKKIRDKTSKKKDE 1059
Score = 32.7 bits (73), Expect = 0.87
Identities = 29/156 (18%), Positives = 65/156 (41%), Gaps = 12/156 (7%)
Query: 183 KRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQK 242
++L + S E + ++ + + + GS+ +M + + E+ ++ +K
Sbjct: 16 QKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSS-----EK 70
Query: 243 LKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQD 302
K RS+++ S + +S+ E + V+E+ +N E+D +VQ
Sbjct: 71 SKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQP 130
Query: 303 EEGDEENKN-------QQGEKLTTSQLKLVKQNSLY 331
E E+K+ + K+ T LK ++ L+
Sbjct: 131 EPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLH 166
Score = 32.7 bits (73), Expect = 0.87
Identities = 72/372 (19%), Positives = 145/372 (38%), Gaps = 69/372 (18%)
Query: 11 RNSKSHVPEQK---SRVDWRRTKRSSISQ---LLDSDEELDSEEFDSDEELDSDESFEND 64
R +K +P K S D + +K+ +Q L + +E S++ + +E ++ S E
Sbjct: 835 RTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGT 894
Query: 65 EELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNI-DL 123
+ D+ ++ P ++ + ++G D S E+ ++ R + +
Sbjct: 895 VDKDTTIMELRDRLPKKQQ----ASASTDGVDKL--------SGKEQSFTSLEVRKVAET 942
Query: 124 QDQEKHLSQE-----DNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIK 178
+++ KHL + + L+ + ++ DQ S++D KQ+ + E+ + D K
Sbjct: 943 KEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDK---KQSKKGTEEKKKPSDFK 999
Query: 179 RGKRKRLSSVMCDSDESD-----------------------DSDILVRKVGVKRPRRVVE 215
+ K SD ++ D + +K+ K ++ E
Sbjct: 1000 KKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDE 1059
Query: 216 ---------DEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEK 266
+G S + + K A + +K KL S ++ + SS + ++
Sbjct: 1060 LSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKE 1119
Query: 267 ESCPSSD---EVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEKLTTSQLK 323
+ C SSD + E E N S + + EE E+NK + ++ T+S+ K
Sbjct: 1120 DGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKK--KQRTSSKKK 1177
Query: 324 LV-----KQNSL 330
V K+NSL
Sbjct: 1178 AVIVKEKKRNSL 1189
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 52.8 bits (125), Expect = 8e-07
Identities = 56/330 (16%), Positives = 144/330 (43%), Gaps = 29/330 (8%)
Query: 6 RHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEF--DSDEELDSDESFEN 63
+ + R+ + + EQ R+ + + ++ + +E++ EE + ++++ +E
Sbjct: 350 QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMR 409
Query: 64 DEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDL 123
++E K + N E+E ++ + +E+ KI + +
Sbjct: 410 EQEEKMQKQEE-NMWEQEEKEWQQQRLPEQKE------KLWEQEKMQEQEEKIWEQEEKI 462
Query: 124 QDQEKHLSQEDNDLNKQTGQIIED---DQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRG 180
+DQE+ QE ++ + ED +QE+ + ++ + Q ++ E D E ++
Sbjct: 463 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQD--ERLREKE 520
Query: 181 KRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKL 240
+R R M +E ++ ++ E E + + E+K E+ ++ +K+
Sbjct: 521 ERMREQKKMWQQEEK-----------MREEKKTQEQEKKTWDQEEKMREEERMREREKKM 569
Query: 241 QKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVV 300
++ +E+ +++ + + + E++ +++ E+EE+ +E +E + +D +
Sbjct: 570 REEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK-MWEQEEKMWEQEEEDKMQ 628
Query: 301 QDEE---GDEENKNQQGEKLTTSQLKLVKQ 327
+ EE EE +Q EK+ + K+ +Q
Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 658
Score = 45.4 bits (106), Expect = 1e-04
Identities = 63/339 (18%), Positives = 151/339 (44%), Gaps = 34/339 (10%)
Query: 5 RRHETRRNSKSHVPEQKSRVDWRRTKR--SSISQLLDSDEELDSEEFDSDEELDSDESFE 62
R+ E R + + +Q+ ++ WR+ +R ++ + +E++ +E E+ E E
Sbjct: 238 RQEEELREQEKKIRKQEEKM-WRQEERLREQEGKMREQEEKMRRQEKRLREQ--EKELRE 294
Query: 63 NDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNID 122
++EL K K E ++ + + + K E+ K+ +
Sbjct: 295 QEKELREQK-----KLREQEEQMQEQEEKMWEQEEKM----------REQEEKMWRQEER 339
Query: 123 LQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKR 182
L +QEK + +++ + Q ++ E D+ +E ++ + E EEE I+ ++
Sbjct: 340 LWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREK 399
Query: 183 K--RLSSVMCDSDE---SDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKR 237
K M + +E + ++ ++ + +R+ E + E E+ ++ ++
Sbjct: 400 KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE 459
Query: 238 EKLQKLKEL-SKQRSRQRRSSGRDFED---SEKESCPSSDEVDEEEEEDNYESDE---DG 290
EK++ +E+ +++ R+ R+ ED ++E ++ ++EE +E DE +
Sbjct: 460 EKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREK 519
Query: 291 DDYIIDDFVV--QDEEGDEENKNQQGEKLTTSQLKLVKQ 327
++ + + + Q+E+ EE K Q+ EK T Q + +++
Sbjct: 520 EERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE 558
Score = 40.4 bits (93), Expect = 0.004
Identities = 56/334 (16%), Positives = 144/334 (43%), Gaps = 26/334 (7%)
Query: 8 ETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEEL-DSEEFDSDEEL--DSDESFEND 64
ET R + + +Q+ + + K +L + E+L + E+ EE + +E +
Sbjct: 406 ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 465
Query: 65 EELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQ 124
EE+ + + E+E + + + + D + + +E++ +++ + ++
Sbjct: 466 EEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQD-ERLREKEERMR 524
Query: 125 DQEKHLSQEDNDLNKQTGQIIED---DQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGK 181
+Q+K QE+ ++ Q E DQE+ + +E+ ++ EEE++ R +
Sbjct: 525 EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKM-----REEEEMMREQ 579
Query: 182 RKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTP---EKTLAAQKRE 238
+++ E ++ + ++ ++ E E E E++ ++ + ++ E
Sbjct: 580 EEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEE 639
Query: 239 KLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDF 298
K+Q+ +E ++ + R + E++ +++ E+EE+ + ++ +
Sbjct: 640 KMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMRE------- 692
Query: 299 VVQDEE--GDEENKNQQGEKLTTSQLKLVKQNSL 330
Q+E+ G EE Q EK+ + K+ Q +
Sbjct: 693 --QEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEM 724
Score = 37.0 bits (84), Expect = 0.046
Identities = 30/138 (21%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Query: 208 KRPRRVVEDEGSSVEMEQK--TPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSE 265
++ R+ E EG E E+K EK L Q++E ++ KEL +Q ++ R ++ E
Sbjct: 259 RQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ--KKLREQEEQMQEQE 316
Query: 266 KESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEKLTTSQLKLV 325
++ +++ E+EE+ + + + Q EE +Q E+L + ++
Sbjct: 317 EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR 376
Query: 326 KQNSLYSFSDHYTHFERV 343
+Q ++ + ER+
Sbjct: 377 EQEKMWEQEEKMQEEERI 394
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 52.4 bits (124), Expect = 1e-06
Identities = 56/276 (20%), Positives = 119/276 (43%), Gaps = 50/276 (18%)
Query: 28 RTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEELDSNKGPD-----CNKTPGSE 82
+ KR+S S+ + + ++ E D+ + ++ E E D N+ + P SE
Sbjct: 35 KPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASE 94
Query: 83 REL------NLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDND 136
+E+ N+ +G + K + + +++++E+ +++ D
Sbjct: 95 KEIVEVKEENIEDATEKGGEKKEAVAA------------------EVKNEEEDQKEDEED 136
Query: 137 LNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESD 196
N++ G+ ++D+++ +ED +K + ED E+ED K+G+ + + D E
Sbjct: 137 QNEEKGEAGKEDKDEK-GEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGE--DGKEKG 193
Query: 197 DSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRS 256
+ + + ED + + ++ K +K K K+KE K+R +
Sbjct: 194 EDE------------KEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKED 241
Query: 257 SGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDD 292
G + E++ KE + D +EEE+ E DE +D
Sbjct: 242 EGGNEEEAGKE------KEDLKEEEEGKEEDEIKED 271
Score = 39.3 bits (90), Expect = 0.009
Identities = 41/179 (22%), Positives = 82/179 (45%), Gaps = 31/179 (17%)
Query: 30 KRSSISQLLDSDEELDSEEFDSDEEL------DSDESFENDEELDSN---KGPDCNKTP- 79
K + +++ + +E+ +E D +EE D DE E D + D N KG D +
Sbjct: 116 KEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKED 175
Query: 80 ---GSERELNLSKIQSEGNDSK---CLINSGNGSTYE---EETNKIKHRNIDLQDQEKHL 130
G + + N + +G D K +G+G E E+ +K + +++ +++ EK
Sbjct: 176 GKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKE- 234
Query: 131 SQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVM 189
++ G+ E E+ +E DL ++ ED+++E+D GK++ S++
Sbjct: 235 --------REDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDD---GKKEEPQSIV 282
Score = 38.1 bits (87), Expect = 0.021
Identities = 38/181 (20%), Positives = 78/181 (43%), Gaps = 21/181 (11%)
Query: 8 ETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEEL 67
E + K V ++ ++ K + + ++ + + E+ DEE ++E E +E
Sbjct: 89 EAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKED 148
Query: 68 DSNKGPDCNKTPGSERELNLSKIQSE----GNDSKCLINSGNGSTYEEETNKIKHRNIDL 123
KG + K + E + E G D K GNG +E+ K
Sbjct: 149 KDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGK-----GNGEDGKEKGEDEKEE---- 199
Query: 124 QDQEKHLSQEDNDLNKQTG--------QIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEE 175
+D+++ ++N+ K+ G ++ ED++E+ +ED N++ ++DL+EE
Sbjct: 200 EDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEE 259
Query: 176 D 176
+
Sbjct: 260 E 260
Score = 33.9 bits (76), Expect = 0.39
Identities = 26/113 (23%), Positives = 57/113 (50%), Gaps = 8/113 (7%)
Query: 211 RRVVEDEGSSVE-MEQKTPEK--TLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKE 267
+ +VE + ++E +K EK +AA+ + + + KE + ++ ++ +G++ +D + E
Sbjct: 95 KEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGE 154
Query: 268 SCPSSDEVDEEEEEDNYESD-----EDGDDYIIDDFVVQDEEGDEENKNQQGE 315
D+ E+ ED E + EDG D ++E +EE++ + G+
Sbjct: 155 EDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGD 207
Score = 33.1 bits (74), Expect = 0.67
Identities = 44/195 (22%), Positives = 80/195 (41%), Gaps = 31/195 (15%)
Query: 141 TGQIIEDDQEKHLSQEDNDLNKQTGQ--IIEDDLEEEDIKRGKRKRLSSVMCDSDESDDS 198
+ Q + + +++ + +ED + N + G+ I E E++I K + + E ++
Sbjct: 59 SAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEA 118
Query: 199 DILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQ--RSRQRRS 256
V +E E E+ E+ A K +K +K +E K+ ++
Sbjct: 119 VAA----------EVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGE 168
Query: 257 SGRDFEDSEK-ESCPSSDE------VDEEEEED---------NYESDEDGDDYIIDDF-V 299
++ ED +K E + E DE+EEED N + E GD D V
Sbjct: 169 DAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKV 228
Query: 300 VQDEEGDEENKNQQG 314
+DE+ E+ K +G
Sbjct: 229 KEDEKEREDGKEDEG 243
Score = 32.3 bits (72), Expect = 1.1
Identities = 31/181 (17%), Positives = 75/181 (41%), Gaps = 12/181 (6%)
Query: 144 IIEDDQEKHLSQEDNDLN------KQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDD 197
++E+D ++ + + K+ ++ E+++E+ K G++K + ++E D
Sbjct: 71 VVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQ 130
Query: 198 SDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSK-QRSRQRRS 256
+ + + E + E+ E +K E ++ ++ K + +
Sbjct: 131 KE---DEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGE 187
Query: 257 SGRDFEDSEKESCPSSDEVDEEEEEDNYESDE--DGDDYIIDDFVVQDEEGDEENKNQQG 314
G++ + EKE + D +E ED E + +G D + + + E+G E+ +
Sbjct: 188 DGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEE 247
Query: 315 E 315
E
Sbjct: 248 E 248
>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
sapiens]
Length = 1150
Score = 52.0 bits (123), Expect = 1e-06
Identities = 68/326 (20%), Positives = 135/326 (41%), Gaps = 53/326 (16%)
Query: 22 SRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFEND-EELD-----SNKGPDC 75
+R +W R QL+ E+L E ++D E D +E + + +E+ S P
Sbjct: 582 TRSEWETLSRGYKQQLV---EKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKT 638
Query: 76 NKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDN 135
K +EL + S+G S+ + EE+ + K + EK +ED
Sbjct: 639 MKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQK-------ELEKSEKEEDE 691
Query: 136 DLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQ-----------IIEDDLEEEDIKRGKRKR 184
D ++++ EDD+E+ + ++ +Q + I+ + + K
Sbjct: 692 DDDRKS----EDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIM 747
Query: 185 LSSVMCDSDESDD--------------SDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEK 230
SV+ D D+ +++L R GV R+ + S E E K EK
Sbjct: 748 SLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGV----RIYKSLLSLPEKEDKK-EK 802
Query: 231 TLAAQKREKLQKLKELSKQRSR---QRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESD 287
++K E+ K +E + +RR SG D + E ++ +++ +D+ E++
Sbjct: 803 DKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETE 862
Query: 288 EDGDDYIIDDFVVQDEEGDEENKNQQ 313
ED + D ++ E +E++++++
Sbjct: 863 EDNNQDEYDPMEAEEAEDEEDDRDEE 888
Score = 39.7 bits (91), Expect = 0.007
Identities = 64/298 (21%), Positives = 122/298 (40%), Gaps = 44/298 (14%)
Query: 21 KSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEELDSNKGPDCNKTPG 80
KS++ R TK+ + + + +EL+ E + DE D D E+D+E + K + +
Sbjct: 659 KSQLIARLTKQLKVEEQKEEQKELEKSEKEEDE--DDDRKSEDDKEEEERKRQEEIERQR 716
Query: 81 SERELNLSKIQSEGNDSKCLINSGNGSTYEEETN-KIKHRNI----DLQDQEKHLSQEDN 135
ER L D +I N + + + I ++ L+D ++H S E +
Sbjct: 717 RERRYILP-------DEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEH-SFEVS 768
Query: 136 DLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDES 195
+ ++++ D + + L + ++D +E+D K K +R DE+
Sbjct: 769 LFAELFNEMLQRDFGVRIYKSLLSLPE------KEDKKEKDKKSKKDERKDKKEERDDET 822
Query: 196 DDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRR 255
D+ RK G + ++ DE R+K K K+ SK
Sbjct: 823 DEPKPKRRKSGDDKDKKEDRDE-------------------RKKEDKRKDDSKDDDETEE 863
Query: 256 SSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQ 313
+ +D E E+ + DE D+ +EE+ + D+ D I+ + + D+E + Q
Sbjct: 864 DNNQD-EYDPMEAEEAEDEEDDRDEEEMTKRDDKRD---INRYCKERPSKDKEKEKTQ 917
Score = 35.8 bits (81), Expect = 0.10
Identities = 38/158 (24%), Positives = 62/158 (39%), Gaps = 20/158 (12%)
Query: 37 LLDSDEELDSEEFDSDEELDS--DESFENDEELDSNK------GPDCNKTPGSERELNLS 88
LL E+ D +E D + D D+ E D+E D K G D +K +
Sbjct: 790 LLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKED 849
Query: 89 KIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDN-DLNKQTGQIIED 147
K + + D N Y+ + D +D+E+ ++D D+N+ +
Sbjct: 850 KRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSK 909
Query: 148 DQEKHLSQE---DNDL--------NKQTGQIIEDDLEE 174
D+EK +Q + DL G ++E DLEE
Sbjct: 910 DKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEE 947
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 52.0 bits (123), Expect = 1e-06
Identities = 27/96 (28%), Positives = 50/96 (52%)
Query: 220 SVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEE 279
S+ + + K + KR+ + KL+ + + SR S + E+ ++E DE +EEE
Sbjct: 599 SLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEE 658
Query: 280 EEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGE 315
+++N +S EDG D + E+GDE ++ + E
Sbjct: 659 DDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 694
Score = 35.0 bits (79), Expect = 0.18
Identities = 44/196 (22%), Positives = 79/196 (40%), Gaps = 33/196 (16%)
Query: 15 SHVPEQKSRVD----WRRTKRSS---ISQLLDSDEELDSEEFDSDEELDSDESFENDEEL 67
+H+P ++ V+ W+R +S +L + ++ D + S + +E
Sbjct: 552 NHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEY 611
Query: 68 DSNKGPDCNK----TPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDL 123
SNK K P S R SK +SE +D EE+ + D
Sbjct: 612 ISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDD-------------EEDED-------DE 651
Query: 124 QDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRK 183
+ E+ E+ D ++ G E E ED D N++ + +DD ++++ + + +
Sbjct: 652 DEDEEEEDDENGDSSEDGGDSSESSSEDE--SEDGDENEEDDEDEDDDEDDDEDEDNESE 709
Query: 184 RLSSVMCDSDESDDSD 199
SS S +S DSD
Sbjct: 710 GSSSSSSSSGDSSDSD 725
Score = 32.3 bits (72), Expect = 1.1
Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
Query: 6 RHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEEL--DSEEFDSDEELDSDESFEN 63
R + S+S +++ D + + DS E+ SE DE D DE+ E+
Sbjct: 631 RTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEED 690
Query: 64 DEELDSNKGPDCNKTPGSERELNLSKIQSEGNDS 97
DE+ D ++ D ++ SE + S + +DS
Sbjct: 691 DEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDS 724
Score = 31.6 bits (70), Expect = 1.9
Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 8/64 (12%)
Query: 257 SGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEK 316
+G ED S SS++ E+ +E N E DED DD +D++ DE+N+++
Sbjct: 662 NGDSSEDGGDSSESSSEDESEDGDE-NEEDDEDEDD-------DEDDDEDEDNESEGSSS 713
Query: 317 LTTS 320
++S
Sbjct: 714 SSSS 717
Score = 29.3 bits (64), Expect = 9.6
Identities = 24/96 (25%), Positives = 37/96 (38%), Gaps = 3/96 (3%)
Query: 13 SKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEELDSNKG 72
+K P KS R T +S D +E+ D E+ D +EE D + D S
Sbjct: 620 TKLRGPNPKSS---RTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS 676
Query: 73 PDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGST 108
+ G E E + + +D + N GS+
Sbjct: 677 SEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSS 712
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 52.0 bits (123), Expect = 1e-06
Identities = 27/96 (28%), Positives = 50/96 (52%)
Query: 220 SVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEE 279
S+ + + K + KR+ + KL+ + + SR S + E+ ++E DE +EEE
Sbjct: 599 SLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEE 658
Query: 280 EEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGE 315
+++N +S EDG D + E+GDE ++ + E
Sbjct: 659 DDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 694
Score = 35.0 bits (79), Expect = 0.18
Identities = 44/196 (22%), Positives = 79/196 (40%), Gaps = 33/196 (16%)
Query: 15 SHVPEQKSRVD----WRRTKRSS---ISQLLDSDEELDSEEFDSDEELDSDESFENDEEL 67
+H+P ++ V+ W+R +S +L + ++ D + S + +E
Sbjct: 552 NHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEY 611
Query: 68 DSNKGPDCNK----TPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDL 123
SNK K P S R SK +SE +D EE+ + D
Sbjct: 612 ISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDD-------------EEDED-------DE 651
Query: 124 QDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRK 183
+ E+ E+ D ++ G E E ED D N++ + +DD ++++ + + +
Sbjct: 652 DEDEEEEDDENGDSSEDGGDSSESSSEDE--SEDGDENEEDDEDEDDDEDDDEDEDNESE 709
Query: 184 RLSSVMCDSDESDDSD 199
SS S +S DSD
Sbjct: 710 GSSSSSSSSGDSSDSD 725
Score = 32.3 bits (72), Expect = 1.1
Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
Query: 6 RHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEEL--DSEEFDSDEELDSDESFEN 63
R + S+S +++ D + + DS E+ SE DE D DE+ E+
Sbjct: 631 RTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEED 690
Query: 64 DEELDSNKGPDCNKTPGSERELNLSKIQSEGNDS 97
DE+ D ++ D ++ SE + S + +DS
Sbjct: 691 DEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDS 724
Score = 31.6 bits (70), Expect = 1.9
Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 8/64 (12%)
Query: 257 SGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEK 316
+G ED S SS++ E+ +E N E DED DD +D++ DE+N+++
Sbjct: 662 NGDSSEDGGDSSESSSEDESEDGDE-NEEDDEDEDD-------DEDDDEDEDNESEGSSS 713
Query: 317 LTTS 320
++S
Sbjct: 714 SSSS 717
Score = 29.3 bits (64), Expect = 9.6
Identities = 24/96 (25%), Positives = 37/96 (38%), Gaps = 3/96 (3%)
Query: 13 SKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEELDSNKG 72
+K P KS R T +S D +E+ D E+ D +EE D + D S
Sbjct: 620 TKLRGPNPKSS---RTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS 676
Query: 73 PDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGST 108
+ G E E + + +D + N GS+
Sbjct: 677 SEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSS 712
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 52.0 bits (123), Expect = 1e-06
Identities = 27/96 (28%), Positives = 50/96 (52%)
Query: 220 SVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEE 279
S+ + + K + KR+ + KL+ + + SR S + E+ ++E DE +EEE
Sbjct: 636 SLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEE 695
Query: 280 EEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGE 315
+++N +S EDG D + E+GDE ++ + E
Sbjct: 696 DDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 731
Score = 35.0 bits (79), Expect = 0.18
Identities = 44/196 (22%), Positives = 79/196 (40%), Gaps = 33/196 (16%)
Query: 15 SHVPEQKSRVD----WRRTKRSS---ISQLLDSDEELDSEEFDSDEELDSDESFENDEEL 67
+H+P ++ V+ W+R +S +L + ++ D + S + +E
Sbjct: 589 NHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEY 648
Query: 68 DSNKGPDCNK----TPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDL 123
SNK K P S R SK +SE +D EE+ + D
Sbjct: 649 ISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDD-------------EEDED-------DE 688
Query: 124 QDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRK 183
+ E+ E+ D ++ G E E ED D N++ + +DD ++++ + + +
Sbjct: 689 DEDEEEEDDENGDSSEDGGDSSESSSEDE--SEDGDENEEDDEDEDDDEDDDEDEDNESE 746
Query: 184 RLSSVMCDSDESDDSD 199
SS S +S DSD
Sbjct: 747 GSSSSSSSSGDSSDSD 762
Score = 32.3 bits (72), Expect = 1.1
Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
Query: 6 RHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEEL--DSEEFDSDEELDSDESFEN 63
R + S+S +++ D + + DS E+ SE DE D DE+ E+
Sbjct: 668 RTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEED 727
Query: 64 DEELDSNKGPDCNKTPGSERELNLSKIQSEGNDS 97
DE+ D ++ D ++ SE + S + +DS
Sbjct: 728 DEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDS 761
Score = 31.6 bits (70), Expect = 1.9
Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 8/64 (12%)
Query: 257 SGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEK 316
+G ED S SS++ E+ +E N E DED DD +D++ DE+N+++
Sbjct: 699 NGDSSEDGGDSSESSSEDESEDGDE-NEEDDEDEDD-------DEDDDEDEDNESEGSSS 750
Query: 317 LTTS 320
++S
Sbjct: 751 SSSS 754
Score = 29.3 bits (64), Expect = 9.6
Identities = 24/96 (25%), Positives = 37/96 (38%), Gaps = 3/96 (3%)
Query: 13 SKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEELDSNKG 72
+K P KS R T +S D +E+ D E+ D +EE D + D S
Sbjct: 657 TKLRGPNPKSS---RTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS 713
Query: 73 PDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGST 108
+ G E E + + +D + N GS+
Sbjct: 714 SEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSS 749
>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
sapiens]
Length = 1710
Score = 52.0 bits (123), Expect = 1e-06
Identities = 68/281 (24%), Positives = 113/281 (40%), Gaps = 36/281 (12%)
Query: 51 SDEEL---DSDESFENDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGS 107
SDEE S ES ++D++ S G + GS + + S+ S +DS S +GS
Sbjct: 5 SDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDS----GSESGS 60
Query: 108 TYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQI 167
E E++ + + Q K + + K + I+ + L ++ +Q Q
Sbjct: 61 QSESESDTSRENKV----QAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQA 116
Query: 168 IEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKT 227
+ EED + SS + D D + G P + D S E E+ +
Sbjct: 117 SSNSGSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSG--SPSQSGSDSESEEEREKSS 174
Query: 228 PEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDN---- 283
++T E K+K K ++R + +G+ +K SS+E D+EE+ DN
Sbjct: 175 CDET--ESDYEPKNKVKS-RKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRS 231
Query: 284 ----------YESDE----DGDDY--IIDDFVVQDEEGDEE 308
Y+ DE D DD + + V Q EE + E
Sbjct: 232 SRRQATVNVSYKEDEEMKTDSDDLLEVCGEDVPQPEEEEFE 272
Score = 35.0 bits (79), Expect = 0.18
Identities = 33/163 (20%), Positives = 74/163 (45%), Gaps = 12/163 (7%)
Query: 8 ETRRNSKSHVPEQKSR-VDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEE 66
E +S S V +K + DW+ + S SQ E + E S +E +SD +E +
Sbjct: 130 EDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESD--YEPKNK 187
Query: 67 LDSNKGPDCNKTPGSERELNLSKIQ---SEGNDSKCLINSGNGSTYEEETNKIKHRNIDL 123
+ S K + +K+ ++ L K Q SE +D + ++ S+ + T + ++
Sbjct: 188 VKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQATVNVSYK---- 243
Query: 124 QDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQ 166
+++ + + +DL + G+ + +E+ + ++ + G+
Sbjct: 244 --EDEEMKTDSDDLLEVCGEDVPQPEEEEFETIERFMDCRIGR 284
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 51.6 bits (122), Expect = 2e-06
Identities = 62/300 (20%), Positives = 124/300 (41%), Gaps = 26/300 (8%)
Query: 19 EQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEELDSNKGPDCNKT 78
EQK R + +R+ + +E + EE + D E + ++ E EE + + +
Sbjct: 711 EQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREK 770
Query: 79 PGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLN 138
ER+ K + G + K G EEET +++E+ E ++
Sbjct: 771 EEGERK----KEERAGKEEKGEEEGDQGEGEEEETEGRG------EEKEEGGEVEGGEVE 820
Query: 139 KQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLE---EEDIKRGKRKRLSSVMCDSDES 195
+ G+ E+++E +E+ + ++ G+ E++ E EE+ + G+ + + E
Sbjct: 821 EGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEG----EEGEG 876
Query: 196 DDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRR 255
+ + G + E+E E E++ + + K ++ E + +
Sbjct: 877 EGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEE 936
Query: 256 SSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGE 315
G + ED E E E + EEEE E +E+G+ + EEG+ E + ++GE
Sbjct: 937 GEG-EGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEG--------EGEEGEGEGEEEEGE 987
Score = 48.5 bits (114), Expect = 2e-05
Identities = 47/241 (19%), Positives = 96/241 (39%), Gaps = 7/241 (2%)
Query: 82 ERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQT 141
E++ +++ G K L + E + K R Q + +E +
Sbjct: 678 EKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGE 737
Query: 142 GQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDIL 201
G+ E D+E+ +E + G+ +E + E+E+ +R K +R +E D +
Sbjct: 738 GEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGE 797
Query: 202 VRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDF 261
+ + + E E+E+ E+ ++ E ++ E ++ G
Sbjct: 798 EEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGK 857
Query: 262 EDSEKESCPSSDEVDE-----EEEEDNYESDEDGDDYIIDD--FVVQDEEGDEENKNQQG 314
+ E E +E +E EEEE E +E+G+ ++ +EEG+ E + ++G
Sbjct: 858 GEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEG 917
Query: 315 E 315
E
Sbjct: 918 E 918
Score = 43.9 bits (102), Expect = 4e-04
Identities = 74/354 (20%), Positives = 138/354 (38%), Gaps = 58/354 (16%)
Query: 23 RVDWRRTKRSSIS-QLLDSDEELDS--EEFDSDEELDSDESFEN-DEELDSNKGPDCNKT 78
R R + S +S Q L EE D +E + E+D+ + E+ E D
Sbjct: 449 RCSERNLQESVLSEQDLMQPEEPDYLLDEMTKEAEIDNSSTVESLGETTDILNMTHIMSL 508
Query: 79 PGSERELNLSKIQS--------EGNDSKCLINSGNGSTYEE----ETNKIKHRNID---- 122
+E+ L LS +Q E L + + YEE + K +++
Sbjct: 509 NSNEKSLKLSPVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIF 568
Query: 123 ----------LQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLN---KQTGQIIE 169
D+E + +E G IE+ QE ++E+ ++ K+ +I+
Sbjct: 569 MTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEE-QEVEANEENVKVHGGRKEKTEILS 627
Query: 170 DDLEEE-DIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKR----PRRVVEDEGSSVEME 224
DDL ++ ++ GK K + + D G + R E + EME
Sbjct: 628 DDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEME 687
Query: 225 QKTPEKTLAAQKREKLQKLKELSKQRSRQR---RSSGRDFEDSEKESCPSSDEVD---EE 278
+ + A+K E ++ E +Q+ R++ + ++ E+ +E +E + EE
Sbjct: 688 RPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREE 747
Query: 279 EEEDNYESDEDGDDYIID-------------DFVVQDEEGDEENKNQQGEKLTT 319
EEE E E+G+ ++ + ++E+G+EE +GE+ T
Sbjct: 748 EEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEET 801
Score = 42.4 bits (98), Expect = 0.001
Identities = 64/337 (18%), Positives = 137/337 (40%), Gaps = 58/337 (17%)
Query: 12 NSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEELDSNK 71
N S E+ S + + + +SQ + + + E SDEE++ E E E+ N
Sbjct: 541 NDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKGN- 599
Query: 72 GPDCNKTPGSERELNL-------SKIQSEGNDSKCLINSGNGS---------------TY 109
G + + +E + + ++I S+ K ++ G T
Sbjct: 600 GIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTC 659
Query: 110 EEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIE 169
EE ++ +H QD+E+ ++D K G++ + + E + K+ G+
Sbjct: 660 EEGSSGAEH----WQDEEREKGEKD----KGRGEMERPGEGEKELAEKEEWKKRDGE--- 708
Query: 170 DDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPE 229
+ E+++ ++G +K + M + E + + + G + E EG E+ E
Sbjct: 709 -EQEQKEREQGHQKERNQEMEEGGEEEHGEG-EEEEGDREEEEEKEGEGK----EEGEGE 762
Query: 230 KTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDE----------EE 279
+ +++E+ ++ KE + + G E E+E+ +E +E E
Sbjct: 763 EVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEG 822
Query: 280 EEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEK 316
+ + E +E+G+ ++EEG+ E + +GE+
Sbjct: 823 KGEREEEEEEGEG--------EEEEGEGEEEEGEGEE 851
Score = 39.7 bits (91), Expect = 0.007
Identities = 63/315 (20%), Positives = 119/315 (37%), Gaps = 40/315 (12%)
Query: 39 DSDEELDSEEFDSDEELDSDESFENDEELDSNKGPDCNKT-----PGSERELNLSKIQSE 93
+ +EE + E + +E +E E +EE KG + + G E E + + E
Sbjct: 825 EREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGE 884
Query: 94 GNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHL 153
G + G G EEE + + +E +E ++ G+ E + E+
Sbjct: 885 GEGEE----EGEGEGEEEEGEGEGEEEGEGEGEE----EEGEGKGEEEGEEGEGEGEEEE 936
Query: 154 SQEDNDLNKQTGQIIEDDLE-EEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRR 212
+ + + + G+ E + E EE+ G+ + + E + +
Sbjct: 937 GEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEE------------E 984
Query: 213 VVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGR---DFEDSEKESC 269
E EG E E++ E+ ++ E + +E + G + E+ E+E
Sbjct: 985 EGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGE 1044
Query: 270 PSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEKLTTSQLKLVKQNS 329
E + EE N E +E+ + E G+EEN+ Q GE+ K+ K
Sbjct: 1045 EREKEGEGEENRRNREEEEEEEGKY-------QETGEEENERQDGEEYK----KVSKIKG 1093
Query: 330 LYSFSDHYTHFERVV 344
+ H T+ ++ V
Sbjct: 1094 SVKYGKHKTYQKKSV 1108
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.128 0.356
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,708,308
Number of Sequences: 37866
Number of extensions: 1124587
Number of successful extensions: 18734
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 351
Number of HSP's successfully gapped in prelim test: 839
Number of HSP's that attempted gapping in prelim test: 7725
Number of HSP's gapped (non-prelim): 6190
length of query: 544
length of database: 18,247,518
effective HSP length: 107
effective length of query: 437
effective length of database: 14,195,856
effective search space: 6203589072
effective search space used: 6203589072
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.