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Search of human proteins with 19923640
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19923640 mitochondrial elongation factor G2 isoform 1 [Homo
sapiens]
(779 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19923640 mitochondrial elongation factor G2 isoform 1 [Homo s... 1539 0.0
gi|25306287 mitochondrial elongation factor G2 isoform 2 [Homo s... 1417 0.0
gi|25306283 mitochondrial elongation factor G2 isoform 3 [Homo s... 1004 0.0
gi|18390331 G elongation factor, mitochondrial 1 [Homo sapiens] 382 e-106
gi|4503483 eukaryotic translation elongation factor 2 [Homo sapi... 135 1e-31
gi|157426893 GUF1 GTPase homolog [Homo sapiens] 98 3e-20
gi|94966754 elongation factor Tu GTP binding domain containing 1... 97 7e-20
gi|239756373 PREDICTED: similar to elongation factor Tu GTP bind... 75 3e-13
gi|239750897 PREDICTED: similar to elongation factor Tu GTP bind... 75 3e-13
gi|239745282 PREDICTED: similar to elongation factor Tu GTP bind... 75 3e-13
gi|217272894 elongation factor Tu GTP binding domain containing ... 70 6e-12
gi|217272892 elongation factor Tu GTP binding domain containing ... 70 6e-12
gi|94966752 elongation factor Tu GTP binding domain containing 1... 68 3e-11
gi|4503471 eukaryotic translation elongation factor 1 alpha 1 [H... 61 5e-09
gi|239757543 PREDICTED: similar to eukaryotic translation elonga... 60 6e-09
gi|4503475 eukaryotic translation elongation factor 1 alpha 2 [H... 60 6e-09
gi|223555963 Hsp70 subfamily B suppressor 1-like protein isoform... 52 2e-06
gi|5729864 Hsp70 subfamily B suppressor 1-like protein isoform 1... 52 2e-06
gi|34147630 Tu translation elongation factor, mitochondrial prec... 52 2e-06
gi|53729339 mitochondrial translational initiation factor 2 prec... 49 1e-05
gi|53729337 mitochondrial translational initiation factor 2 prec... 49 1e-05
gi|194018522 G1 to S phase transition 1 isoform 3 [Homo sapiens] 44 4e-04
gi|194097354 G1 to S phase transition 1 isoform 2 [Homo sapiens] 44 4e-04
gi|194018520 G1 to S phase transition 1 isoform 1 [Homo sapiens] 44 4e-04
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 44 4e-04
gi|46094014 peptide chain release factor 3 [Homo sapiens] 42 0.002
gi|54607086 eukaryotic elongation factor, selenocysteine-tRNA-sp... 37 0.054
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 32 3.0
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 32 3.0
gi|4506365 RAB2A, member RAS oncogene family [Homo sapiens] 31 5.0
>gi|19923640 mitochondrial elongation factor G2 isoform 1 [Homo
sapiens]
Length = 779
Score = 1539 bits (3985), Expect = 0.0
Identities = 779/779 (100%), Positives = 779/779 (100%)
Query: 1 MLTNLRIFAMSHQTIPSVYINNICCYKIRASLKRLKPHVPLGRNCSSLPGLIGNDIKSLH 60
MLTNLRIFAMSHQTIPSVYINNICCYKIRASLKRLKPHVPLGRNCSSLPGLIGNDIKSLH
Sbjct: 1 MLTNLRIFAMSHQTIPSVYINNICCYKIRASLKRLKPHVPLGRNCSSLPGLIGNDIKSLH 60
Query: 61 SIINPPIAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERG 120
SIINPPIAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERG
Sbjct: 61 SIINPPIAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERG 120
Query: 121 ITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVW 180
ITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVW
Sbjct: 121 ITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVW 180
Query: 181 RQADKHNIPRICFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVM 240
RQADKHNIPRICFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVM
Sbjct: 181 RQADKHNIPRICFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVM 240
Query: 241 KEKLLWNCNSNDGKDFERKPLLEMNDPELLKETTEARNALIEQVADLDDEFADLVLEEFS 300
KEKLLWNCNSNDGKDFERKPLLEMNDPELLKETTEARNALIEQVADLDDEFADLVLEEFS
Sbjct: 241 KEKLLWNCNSNDGKDFERKPLLEMNDPELLKETTEARNALIEQVADLDDEFADLVLEEFS 300
Query: 301 ENFDLLPAEKLQTAIHRVTLAQTAVPVLCGSALKNKGIQPLLDAVTMYLPSPEERNYEFL 360
ENFDLLPAEKLQTAIHRVTLAQTAVPVLCGSALKNKGIQPLLDAVTMYLPSPEERNYEFL
Sbjct: 301 ENFDLLPAEKLQTAIHRVTLAQTAVPVLCGSALKNKGIQPLLDAVTMYLPSPEERNYEFL 360
Query: 361 QWYKDDLCALAFKVLHDKQRGPLVFMRIYSGTIKPQLAIHNINGNCTERISRLLLPFADQ 420
QWYKDDLCALAFKVLHDKQRGPLVFMRIYSGTIKPQLAIHNINGNCTERISRLLLPFADQ
Sbjct: 361 QWYKDDLCALAFKVLHDKQRGPLVFMRIYSGTIKPQLAIHNINGNCTERISRLLLPFADQ 420
Query: 421 HVEIPSLTAGNIALTVGLKHTATGDTIVSSKSSALAAARRAEREGEKKHRQNNEAERLLL 480
HVEIPSLTAGNIALTVGLKHTATGDTIVSSKSSALAAARRAEREGEKKHRQNNEAERLLL
Sbjct: 421 HVEIPSLTAGNIALTVGLKHTATGDTIVSSKSSALAAARRAEREGEKKHRQNNEAERLLL 480
Query: 481 AGVEIPEPVFFCTIEPPSLSKQPDLEHALKCLQREDPSLKVRLDPDSGQTVLCGMGELHI 540
AGVEIPEPVFFCTIEPPSLSKQPDLEHALKCLQREDPSLKVRLDPDSGQTVLCGMGELHI
Sbjct: 481 AGVEIPEPVFFCTIEPPSLSKQPDLEHALKCLQREDPSLKVRLDPDSGQTVLCGMGELHI 540
Query: 541 EIIHDRIKREYGLETYLGPLQVAYRETILNSVRATDTLDRTLGDKRHLVTVEVEARPIET 600
EIIHDRIKREYGLETYLGPLQVAYRETILNSVRATDTLDRTLGDKRHLVTVEVEARPIET
Sbjct: 541 EIIHDRIKREYGLETYLGPLQVAYRETILNSVRATDTLDRTLGDKRHLVTVEVEARPIET 600
Query: 601 SSVMPVIEFEYAESINEGLLKVSQEAIENGIHSACLQGPLLGSPIQDVAITLHSLTIHPG 660
SSVMPVIEFEYAESINEGLLKVSQEAIENGIHSACLQGPLLGSPIQDVAITLHSLTIHPG
Sbjct: 601 SSVMPVIEFEYAESINEGLLKVSQEAIENGIHSACLQGPLLGSPIQDVAITLHSLTIHPG 660
Query: 661 TSTTMISACVSRCVQKALKKADKQVLEPLMNLEVTVARDYLSPVLADLAQRRGNIQEIQT 720
TSTTMISACVSRCVQKALKKADKQVLEPLMNLEVTVARDYLSPVLADLAQRRGNIQEIQT
Sbjct: 661 TSTTMISACVSRCVQKALKKADKQVLEPLMNLEVTVARDYLSPVLADLAQRRGNIQEIQT 720
Query: 721 RQDNKVVIGFVPLAEIMGYSTVLRTLTSGSATFALELSTYQAMNPQDQNTLLNRRSGLT 779
RQDNKVVIGFVPLAEIMGYSTVLRTLTSGSATFALELSTYQAMNPQDQNTLLNRRSGLT
Sbjct: 721 RQDNKVVIGFVPLAEIMGYSTVLRTLTSGSATFALELSTYQAMNPQDQNTLLNRRSGLT 779
>gi|25306287 mitochondrial elongation factor G2 isoform 2 [Homo
sapiens]
Length = 732
Score = 1417 bits (3668), Expect = 0.0
Identities = 732/779 (93%), Positives = 732/779 (93%), Gaps = 47/779 (6%)
Query: 1 MLTNLRIFAMSHQTIPSVYINNICCYKIRASLKRLKPHVPLGRNCSSLPGLIGNDIKSLH 60
MLTNLRIFAMSHQTIPSVYINNICCYKIRASLKRLKPHVPLGRNCSSLPGLIGNDIKSLH
Sbjct: 1 MLTNLRIFAMSHQTIPSVYINNICCYKIRASLKRLKPHVPLGRNCSSLPGLIGNDIKSLH 60
Query: 61 SIINPPIAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERG 120
SIINPPIAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERG
Sbjct: 61 SIINPPIAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERG 120
Query: 121 ITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVW 180
ITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVW
Sbjct: 121 ITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVW 180
Query: 181 RQADKHNIPRICFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVM 240
RQADKHNIPRICFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVM
Sbjct: 181 RQADKHNIPRICFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVM 240
Query: 241 KEKLLWNCNSNDGKDFERKPLLEMNDPELLKETTEARNALIEQVADLDDEFADLVLEEFS 300
KEKLLWNCNSNDGKDFERKPLLEMNDPELLKETTEARNALIEQVADLDDEFADLVLEEFS
Sbjct: 241 KEKLLWNCNSNDGKDFERKPLLEMNDPELLKETTEARNALIEQVADLDDEFADLVLEEFS 300
Query: 301 ENFDLLPAEKLQTAIHRVTLAQTAVPVLCGSALKNKGIQPLLDAVTMYLPSPEERNYEFL 360
ENFDLLPAEKLQTAIHRVTLAQTAVPVLCGSALKNKGIQPLLDAVTMYLPSPEERNYEFL
Sbjct: 301 ENFDLLPAEKLQTAIHRVTLAQTAVPVLCGSALKNKGIQPLLDAVTMYLPSPEERNYEFL 360
Query: 361 QWYKDDLCALAFKVLHDKQRGPLVFMRIYSGTIKPQLAIHNINGNCTERISRLLLPFADQ 420
ERISRLLLPFADQ
Sbjct: 361 -----------------------------------------------ERISRLLLPFADQ 373
Query: 421 HVEIPSLTAGNIALTVGLKHTATGDTIVSSKSSALAAARRAEREGEKKHRQNNEAERLLL 480
HVEIPSLTAGNIALTVGLKHTATGDTIVSSKSSALAAARRAEREGEKKHRQNNEAERLLL
Sbjct: 374 HVEIPSLTAGNIALTVGLKHTATGDTIVSSKSSALAAARRAEREGEKKHRQNNEAERLLL 433
Query: 481 AGVEIPEPVFFCTIEPPSLSKQPDLEHALKCLQREDPSLKVRLDPDSGQTVLCGMGELHI 540
AGVEIPEPVFFCTIEPPSLSKQPDLEHALKCLQREDPSLKVRLDPDSGQTVLCGMGELHI
Sbjct: 434 AGVEIPEPVFFCTIEPPSLSKQPDLEHALKCLQREDPSLKVRLDPDSGQTVLCGMGELHI 493
Query: 541 EIIHDRIKREYGLETYLGPLQVAYRETILNSVRATDTLDRTLGDKRHLVTVEVEARPIET 600
EIIHDRIKREYGLETYLGPLQVAYRETILNSVRATDTLDRTLGDKRHLVTVEVEARPIET
Sbjct: 494 EIIHDRIKREYGLETYLGPLQVAYRETILNSVRATDTLDRTLGDKRHLVTVEVEARPIET 553
Query: 601 SSVMPVIEFEYAESINEGLLKVSQEAIENGIHSACLQGPLLGSPIQDVAITLHSLTIHPG 660
SSVMPVIEFEYAESINEGLLKVSQEAIENGIHSACLQGPLLGSPIQDVAITLHSLTIHPG
Sbjct: 554 SSVMPVIEFEYAESINEGLLKVSQEAIENGIHSACLQGPLLGSPIQDVAITLHSLTIHPG 613
Query: 661 TSTTMISACVSRCVQKALKKADKQVLEPLMNLEVTVARDYLSPVLADLAQRRGNIQEIQT 720
TSTTMISACVSRCVQKALKKADKQVLEPLMNLEVTVARDYLSPVLADLAQRRGNIQEIQT
Sbjct: 614 TSTTMISACVSRCVQKALKKADKQVLEPLMNLEVTVARDYLSPVLADLAQRRGNIQEIQT 673
Query: 721 RQDNKVVIGFVPLAEIMGYSTVLRTLTSGSATFALELSTYQAMNPQDQNTLLNRRSGLT 779
RQDNKVVIGFVPLAEIMGYSTVLRTLTSGSATFALELSTYQAMNPQDQNTLLNRRSGLT
Sbjct: 674 RQDNKVVIGFVPLAEIMGYSTVLRTLTSGSATFALELSTYQAMNPQDQNTLLNRRSGLT 732
>gi|25306283 mitochondrial elongation factor G2 isoform 3 [Homo
sapiens]
Length = 513
Score = 1004 bits (2597), Expect = 0.0
Identities = 503/505 (99%), Positives = 504/505 (99%)
Query: 1 MLTNLRIFAMSHQTIPSVYINNICCYKIRASLKRLKPHVPLGRNCSSLPGLIGNDIKSLH 60
MLTNLRIFAMSHQTIPSVYINNICCYKIRASLKRLKPHVPLGRNCSSLPGLIGNDIKSLH
Sbjct: 1 MLTNLRIFAMSHQTIPSVYINNICCYKIRASLKRLKPHVPLGRNCSSLPGLIGNDIKSLH 60
Query: 61 SIINPPIAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERG 120
SIINPPIAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERG
Sbjct: 61 SIINPPIAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERG 120
Query: 121 ITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVW 180
ITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVW
Sbjct: 121 ITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVW 180
Query: 181 RQADKHNIPRICFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVM 240
RQADKHNIPRICFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVM
Sbjct: 181 RQADKHNIPRICFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVM 240
Query: 241 KEKLLWNCNSNDGKDFERKPLLEMNDPELLKETTEARNALIEQVADLDDEFADLVLEEFS 300
KEKLLWNCNSNDGKDFERKPLLEMNDPELLKETTEARNALIEQVADLDDEFADLVLEEFS
Sbjct: 241 KEKLLWNCNSNDGKDFERKPLLEMNDPELLKETTEARNALIEQVADLDDEFADLVLEEFS 300
Query: 301 ENFDLLPAEKLQTAIHRVTLAQTAVPVLCGSALKNKGIQPLLDAVTMYLPSPEERNYEFL 360
ENFDLLPAEKLQTAIHRVTLAQTAVPVLCGSALKNKGIQPLLDAVTMYLPSPEERNYEFL
Sbjct: 301 ENFDLLPAEKLQTAIHRVTLAQTAVPVLCGSALKNKGIQPLLDAVTMYLPSPEERNYEFL 360
Query: 361 QWYKDDLCALAFKVLHDKQRGPLVFMRIYSGTIKPQLAIHNINGNCTERISRLLLPFADQ 420
QWYKDDLCALAFKVLHDKQRGPLVFMRIYSGTIKPQLAIHNINGNCTERISRLLLPFADQ
Sbjct: 361 QWYKDDLCALAFKVLHDKQRGPLVFMRIYSGTIKPQLAIHNINGNCTERISRLLLPFADQ 420
Query: 421 HVEIPSLTAGNIALTVGLKHTATGDTIVSSKSSALAAARRAEREGEKKHRQNNEAERLLL 480
HVEIPSLTAGNIALTVGLKHTATGDTIVSSKSSALAAARRAEREGEKKHRQNNEAERLLL
Sbjct: 421 HVEIPSLTAGNIALTVGLKHTATGDTIVSSKSSALAAARRAEREGEKKHRQNNEAERLLL 480
Query: 481 AGVEIPEPVFFCTIEPPSLSKQPDL 505
AGVEIPEPVFFCTIEPPSLSKQP +
Sbjct: 481 AGVEIPEPVFFCTIEPPSLSKQPGI 505
>gi|18390331 G elongation factor, mitochondrial 1 [Homo sapiens]
Length = 751
Score = 382 bits (981), Expect = e-106
Identities = 257/731 (35%), Positives = 368/731 (50%), Gaps = 60/731 (8%)
Query: 66 PIAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGD---TVTDFMAQERERGIT 122
P KIRNIGI AHID+GKTT TER+LYY+G + +V D V D M ER+RGIT
Sbjct: 42 PNEKIRNIGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGIT 101
Query: 123 IQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQ 182
IQSAA WK +N+IDTPGHVDFT+EVER LRVLDGAV V A GV+ QT+TV RQ
Sbjct: 102 IQSAATYTMWKDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQ 161
Query: 183 ADKHNIPRICFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVMKE 242
++N+P + F+NK+D+ G++ A++ +R KL +Q+P+G FKG+VD++ +
Sbjct: 162 MKRYNVPFLTFINKLDRMGSNPARALQQMRSKLNHNAAFMQIPMGLEGNFKGIVDLIEER 221
Query: 243 KLLWNCNSNDGKDFERKPLLEMNDPELLKETTEARNALIEQVADLDDEFADLVLEEFSEN 302
+ + DG DF + EL T+ R LIE VA+ D++ ++ LEE
Sbjct: 222 AIYF-----DG-DFGQIVRYGEIPAELRAAATDHRQELIECVANSDEQLGEMFLEE---- 271
Query: 303 FDLLPAEKLQTAIHRVTLAQTAVPVLCGSALKNKGIQPLLDAVTMYLPSPEE-RNYEFLQ 361
+ L+ AI R TL ++ PV GSALKNKG+QPLLDAV YLP+P E +NY L
Sbjct: 272 -KIPSISDLKLAIRRATLKRSFTPVFLGSALKNKGVQPLLDAVLEYLPNPSEVQNYAILN 330
Query: 362 WYKDD-----------------LCALAFKVLHDKQRGPLVFMRIYSGTIKPQLAIHNING 404
D LAFK L + G L ++R Y G +K I+N
Sbjct: 331 KEDDSKEKTKILMNSSRDNSHPFVGLAFK-LEVGRFGQLTYVRSYQGELKKGDTIYNTRT 389
Query: 405 NCTERISRLLLPFADQHVEIPSLTAGNIALTVGLKHTATGDTIVSSKSSALAAARRAERE 464
R+ RL AD ++ + AG+I G+ A+GDT +S L+
Sbjct: 390 RKKVRLQRLARMHADMMEDVEEVYAGDICALFGI-DCASGDTFTDKANSGLS-------- 440
Query: 465 GEKKHRQNNEAERLLLAGVEIPEPVFFCTIEPPSLSKQPDLEHALKCLQREDPSLKVRLD 524
+ + +P+PV ++P + + + REDP+ KV D
Sbjct: 441 ---------------MESIHVPDPVISIAMKPSNKNDLEKFSKGIGRFTREDPTFKVYFD 485
Query: 525 PDSGQTVLCGMGELHIEIIHDRIKREYGLETYLGPLQVAYRETILNSVRATDTLDRTLGD 584
++ +TV+ GMGELH+EI R++REYG G +VA+RETI V T + G
Sbjct: 486 TENKETVISGMGELHLEIYAQRLEREYGCPCITGKPKVAFRETITAPVPFDFTHKKQSGG 545
Query: 585 KRHLVTVEVEARPIETSSVMPVIEFEYAESINEGLLKVSQEAIENGIHSACLQGPLLGSP 644
V P++ +EF E+ + K A+E G AC +GPL G
Sbjct: 546 AGQYGKVIGVLEPLDPEDYTK-LEFS-DETFGSNIPKQFVPAVEKGFLDACEKGPLSGHK 603
Query: 645 IQDVAITLHSLTIHPGTSTTM-ISACVSRCVQKALKKADKQVLEPLMNLEVTVARDYLSP 703
+ + L H S + +++AL A +LEP+M +EV ++
Sbjct: 604 LSGLRFVLQDGAHHMVDSNEISFIRAGEGALKQALANATLCILEPIMAVEVVAPNEFQGQ 663
Query: 704 VLADLAQRRGNIQEIQTRQDNKVVIGFVPLAEIMGYSTVLRTLTSGSATFALELSTYQAM 763
V+A + +R G I +D + VPL ++ GYST LR+ T G + +E S YQ
Sbjct: 664 VIAGINRRHGVITGQDGVEDYFTLYADVPLNDMFGYSTELRSCTEGKGEYTMEYSRYQPC 723
Query: 764 NPQDQNTLLNR 774
P Q ++N+
Sbjct: 724 LPSTQEDVINK 734
>gi|4503483 eukaryotic translation elongation factor 2 [Homo
sapiens]
Length = 858
Score = 135 bits (340), Expect = 1e-31
Identities = 191/826 (23%), Positives = 333/826 (40%), Gaps = 176/826 (21%)
Query: 68 AKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDT-VTDFMAQERERGITIQSA 126
A IRN+ ++AH+D GK+T T+ ++ +G S G+T TD E+ER ITI+S
Sbjct: 17 ANIRNMSVIAHVDHGKSTLTDSLVCKAGIIAS---ARAGETRFTDTRKDEQERCITIKST 73
Query: 127 AVTF----------------DWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASA 170
A++ D G+ +NLID+PGHVDF+ EV LRV DGA+ V D +
Sbjct: 74 AISLFYELSENDLNFIKQSKDGAGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVS 133
Query: 171 GVEAQTLTVWRQADKHNIPRICFLNKMDKTGASFKYAVESIR---EKLKAKPLLLQLPIG 227
GV QT TV RQA I + +NKMD+ + E + +++ ++ G
Sbjct: 134 GVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYG 193
Query: 228 EAKTFKGVVDVVMKEKLLWNCNSNDGKDFERKPLLEMNDPELLKETTEARNAL-----IE 282
E ++ G + +M + +L G L + + + K + L +
Sbjct: 194 EGES--GPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGEGQLGPAERAK 251
Query: 283 QVADL-----DDEFADLVLEEFSEN---------------FDLLPAEKLQTAIHRVTLAQ 322
+V D+ D + D +FS++ L P K+ AI +
Sbjct: 252 KVEDMMKKLWGDRYFDPANGKFSKSATSPEGKKLPRTFCQLILDPIFKVFDAIMNFKKEE 311
Query: 323 TA-----VPVLCGSALKNKGIQPLLDAV---------------TMYLPSP-EERNYEFLQ 361
TA + + S K+K +PLL AV T++LPSP + Y
Sbjct: 312 TAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCEL 371
Query: 362 WYK---DDLCALAFKVLHDKQRGPLV-----------------FMRIYSGTIKPQLAIHN 401
Y+ DD A+ K K GPL+ F R++SG + L +
Sbjct: 372 LYEGPPDDEAAMGIKSCDPK--GPLMMYISKMVPTSDKGRFYAFGRVFSGLVSTGLKVRI 429
Query: 402 INGNCT---------ERISRLLLPFADQHVEIPSLTAGNIALTVGLKHTATGDTIVSSKS 452
+ N T + I R +L I + GNI VG+ +++
Sbjct: 430 MGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITT-- 487
Query: 453 SALAAARRAEREGEKKHRQNNEAERLLLAGVEIPEPVFFCTIEPPSLSKQPDLEHALKCL 512
+H N + ++ PV +E + + P L LK L
Sbjct: 488 --------------FEHAHNMRVMKFSVS------PVVRVAVEAKNPADLPKLVEGLKRL 527
Query: 513 QREDPSLKVRLDPDSGQTVLCGMGELHIEIIHDRIKREYG-LETYLGPLQVAYRETILNS 571
+ DP ++ ++ +SG+ ++ G GELH+EI ++ ++ + V+YRET+
Sbjct: 528 AKSDPMVQCIIE-ESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEE 586
Query: 572 VRATDTLDRTLGDKRHLVTVEVEARPI-----------ETSS----------VMPVIEFE 610
++ L + +H + ++ARP E S+ + E++
Sbjct: 587 ---SNVLCLSKSPNKH-NRLYMKARPFPDGLAEDIDKGEVSARQELKQRARYLAEKYEWD 642
Query: 611 YAES------------------INEGL--LKVSQEAIENGIHSACLQGPLLGSPIQDVAI 650
AE+ I +G+ L ++++ G A +G L ++ V
Sbjct: 643 VAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRF 702
Query: 651 TLHSLTIHPGT---STTMISACVSRCVQKALKKADKQVLEPLMNLEVTVARDYLSPVLAD 707
+H +T+H I RC+ ++ A +++EP+ +E+ + +
Sbjct: 703 DVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGV 762
Query: 708 LAQRRGNI-QEIQTRQDNKVVI-GFVPLAEIMGYSTVLRTLTSGSA 751
L ++RG++ +E Q V+ ++P+ E G++ LR+ T G A
Sbjct: 763 LNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQA 808
>gi|157426893 GUF1 GTPase homolog [Homo sapiens]
Length = 669
Score = 97.8 bits (242), Expect = 3e-20
Identities = 56/141 (39%), Positives = 86/141 (60%), Gaps = 7/141 (4%)
Query: 66 PIAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITI-- 123
P+ IRN I+AH+D GK+T +R+L +G ++ + V D + ERERGIT+
Sbjct: 64 PVENIRNFSIVAHVDHGKSTLADRLLELTG---TIDKTKNNKQVLDKLQVERERGITVKA 120
Query: 124 QSAAVTFDWKG--YRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWR 181
Q+A++ ++ +G Y +NLIDTPGHVDF+ EV R L G + V DA+ G++AQT+ +
Sbjct: 121 QTASLFYNCEGKQYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEGIQAQTVANFF 180
Query: 182 QADKHNIPRICFLNKMDKTGA 202
A + + I +NK+D A
Sbjct: 181 LAFEAQLSVIPVINKIDLKNA 201
Score = 42.7 bits (99), Expect = 0.001
Identities = 54/248 (21%), Positives = 99/248 (39%), Gaps = 38/248 (15%)
Query: 331 SALKNKGIQPLLDAVTMYLPSPEERNYEFLQWYKDDLCALAFKVLHDKQRGPLVFMRIYS 390
SA ++ +L A+ +P P+ K+ L AL F D+ RG + + ++
Sbjct: 225 SAKLGTNVESVLQAIIERIPPPKVHR-------KNPLRALVFDSTFDQYRGVIANVALFD 277
Query: 391 GTIKPQLAIHNINGNCTERISRLLLPFADQHVEIPSLTAGNIA-LTVGLKHTAT---GDT 446
G + I + + T ++ + + ++ L AG + L G+K GDT
Sbjct: 278 GVVSKGDKIVSAHTQKTYEVNEVGVLNPNEQ-PTHKLYAGQVGYLIAGMKDVTEAQIGDT 336
Query: 447 IVSSKSSALAAARRAEREGEKKHRQNNEAERLLLAGVEIPEPVFFCTIEPPSLSKQPDLE 506
+ H+Q E L G + +P+ F + P S+ +L+
Sbjct: 337 LCL-------------------HKQPVEP----LPGFKSAKPMVFAGMYPLDQSEYNNLK 373
Query: 507 HALKCLQREDPSLKVRLDPDSGQTV---LCGMGELHIEIIHDRIKREYGLETYLGPLQVA 563
A++ L D S+ V D L +G LH+E+ + R+++EY L V
Sbjct: 374 SAIEKLTLNDSSVTVHRDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNASVILTTPTVP 433
Query: 564 YRETILNS 571
Y+ + +S
Sbjct: 434 YKAVLSSS 441
Score = 30.8 bits (68), Expect = 5.0
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
Query: 684 QVLEPLMNLEVTVARDYLSPVLADLAQRRGNIQEIQTRQDNKVVIGFV-PLAEIM-GYST 741
+ LEP++ + +Y ++ RR + + N+V++ ++ PL EI+ +
Sbjct: 468 EYLEPVVLGTIITPDEYTGKIMMLCEARRAVQKNMIFIDQNRVMLKYLFPLNEIVVDFYD 527
Query: 742 VLRTLTSGSATFALELSTYQAMNPQDQNTLLN 773
L++L+SG A+F E + YQ + LLN
Sbjct: 528 SLKSLSSGYASFDYEDAGYQTAELVKMDILLN 559
>gi|94966754 elongation factor Tu GTP binding domain containing 1
isoform 1 [Homo sapiens]
Length = 1120
Score = 96.7 bits (239), Expect = 7e-20
Identities = 59/155 (38%), Positives = 89/155 (57%), Gaps = 10/155 (6%)
Query: 68 AKIRNIGIMAHIDAGKTTTTERILYYSGY--TRSLGDVDDGDTVTDFMAQERERGITIQS 125
A IRNI ++AH+D GKTT + ++ +G +R G + D+ D E+ RGIT++S
Sbjct: 17 ANIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYMDSRED----EQIRGITMKS 72
Query: 126 AAVTFDW----KGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWR 181
+A++ + + Y +NLID+PGHVDF+ EV +R+ DG + V DA GV QT V R
Sbjct: 73 SAISLHYATGNEEYLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLR 132
Query: 182 QADKHNIPRICFLNKMDKTGASFKYAVESIREKLK 216
QA NI + +NK+D+ K+ + LK
Sbjct: 133 QAWLENIRPVLVINKIDRLIVELKFTPQEAYSHLK 167
Score = 41.6 bits (96), Expect = 0.003
Identities = 25/105 (23%), Positives = 53/105 (50%), Gaps = 3/105 (2%)
Query: 488 PVFFCTIEPPSLSKQPDLEHALKCLQREDPSLKVRLDPDSGQTVLCGMGELHIEIIHDRI 547
P+ +EP S+ P L +K L + DP +++ L ++G+ VL GE+H++ D +
Sbjct: 616 PIVRVAVEPKHPSEMPQLVKGMKLLNQADPCVQI-LIQETGEHVLVTAGEVHLQRCLDDL 674
Query: 548 KREYG-LETYLGPLQVAYRETILNSVRATDTLDRTLGDKRHLVTV 591
K + + + + +RETI + D ++ +G ++ + +
Sbjct: 675 KERFAKIHISVSEPIIPFRETITKPPK-VDMVNEEIGKQQKVAVI 718
Score = 38.9 bits (89), Expect = 0.018
Identities = 26/110 (23%), Positives = 55/110 (50%), Gaps = 3/110 (2%)
Query: 660 GTSTTMISACVSRCVQKALKKADKQVLEPLMNLEVTVARDYLSPVLADLAQRRGNI--QE 717
G + + A + + AL+ ++++ + ++ D L V A L++R G + +E
Sbjct: 955 GPFSGQLIATMKEACRYALQVKPQRLMAAMYTCDIMATGDVLGRVYAVLSKREGRVLQEE 1014
Query: 718 IQTRQDNKVVIGFVPLAEIMGYSTVLRTLTSGSATFALELSTYQAMNPQD 767
++ D ++ +P+AE G++ +R TSG A+ L S ++ + P D
Sbjct: 1015 MKEGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEII-PSD 1063
>gi|239756373 PREDICTED: similar to elongation factor Tu GTP binding
domain containing 1 [Homo sapiens]
Length = 263
Score = 74.7 bits (182), Expect = 3e-13
Identities = 43/111 (38%), Positives = 68/111 (61%), Gaps = 10/111 (9%)
Query: 68 AKIRNIGIMAHIDAGKTTTTERILYYSGYTRS--LGDVDDGDTVTDFMAQERERGITIQS 125
A IRNI ++AH+D GKTT + ++ +G S G + D+ D E+ RGIT++S
Sbjct: 148 ANIRNICVLAHVDRGKTTLADCLISSNGIISSHLAGKLRYMDSRED----EQIRGITMKS 203
Query: 126 AAVTFDW----KGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGV 172
+A++ + + Y +NLID+PGH+DF+ +V +R+ DG + V DA GV
Sbjct: 204 SAISLHYATGNEEYLINLIDSPGHMDFSSDVSTAVRICDGCIIVVDAVEGV 254
>gi|239750897 PREDICTED: similar to elongation factor Tu GTP binding
domain containing 1 [Homo sapiens]
Length = 263
Score = 74.7 bits (182), Expect = 3e-13
Identities = 43/111 (38%), Positives = 68/111 (61%), Gaps = 10/111 (9%)
Query: 68 AKIRNIGIMAHIDAGKTTTTERILYYSGYTRS--LGDVDDGDTVTDFMAQERERGITIQS 125
A IRNI ++AH+D GKTT + ++ +G S G + D+ D E+ RGIT++S
Sbjct: 148 ANIRNICVLAHVDRGKTTLADCLISSNGIISSHLAGKLRYMDSRED----EQIRGITMKS 203
Query: 126 AAVTFDW----KGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGV 172
+A++ + + Y +NLID+PGH+DF+ +V +R+ DG + V DA GV
Sbjct: 204 SAISLHYATGNEEYLINLIDSPGHMDFSSDVSTAVRICDGCIIVVDAVEGV 254
>gi|239745282 PREDICTED: similar to elongation factor Tu GTP binding
domain containing 1 [Homo sapiens]
Length = 263
Score = 74.7 bits (182), Expect = 3e-13
Identities = 43/111 (38%), Positives = 68/111 (61%), Gaps = 10/111 (9%)
Query: 68 AKIRNIGIMAHIDAGKTTTTERILYYSGYTRS--LGDVDDGDTVTDFMAQERERGITIQS 125
A IRNI ++AH+D GKTT + ++ +G S G + D+ D E+ RGIT++S
Sbjct: 148 ANIRNICVLAHVDRGKTTLADCLISSNGIISSHLAGKLRYMDSRED----EQIRGITMKS 203
Query: 126 AAVTFDW----KGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGV 172
+A++ + + Y +NLID+PGH+DF+ +V +R+ DG + V DA GV
Sbjct: 204 SAISLHYATGNEEYLINLIDSPGHMDFSSDVSTAVRICDGCIIVVDAVEGV 254
>gi|217272894 elongation factor Tu GTP binding domain containing 2
isoform b [Homo sapiens]
Length = 937
Score = 70.5 bits (171), Expect = 6e-12
Identities = 46/135 (34%), Positives = 71/135 (52%), Gaps = 6/135 (4%)
Query: 70 IRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITIQSAAVT 129
IRN+ + H+ GKT + ++ + + D TD + E+ERG+ I+S VT
Sbjct: 94 IRNVTLCGHLHHGKTCFVDCLIEQT-HPEIRKRYDQDLCYTDILFTEQERGVGIKSTPVT 152
Query: 130 F---DWKG--YRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQAD 184
D KG Y N++DTPGHV+F+ EV LR+ DG V DA+ GV T + + A
Sbjct: 153 VVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAV 212
Query: 185 KHNIPRICFLNKMDK 199
+ + +NK+D+
Sbjct: 213 QERLAVTVCINKIDR 227
Score = 67.8 bits (164), Expect = 4e-11
Identities = 92/441 (20%), Positives = 176/441 (39%), Gaps = 81/441 (18%)
Query: 385 FMRIYSGTIKPQLAIHNINGNCTER---------ISRLLLPFADQHVEIPSLTAGNIALT 435
F R+ SGTI + + N T + RL + A H+E+ + AGN L
Sbjct: 458 FGRVLSGTIHAGQPVKVLGENYTLEDEEDSQICTVGRLWISVARYHIEVNRVPAGNWVLI 517
Query: 436 VGLKHTATGDTIVSSKSSALAAARRAEREGEKKHRQNNEAERLLLAGVEIPEPVFFCTIE 495
G+ K++ + R E + + N + +A +E
Sbjct: 518 EGVDQPIV-------KTATITEPRGNEEAQIFRPLKFNTTSVIKIA------------VE 558
Query: 496 PPSLSKQPDLEHALKCLQREDPSLKVRLDPDSGQTVLCGMGELHIE-IIHDRIKREYGLE 554
P + S+ P + L+ + + PSL +++ +SG+ V+ G GEL+++ ++HD K ++
Sbjct: 559 PVNPSELPKMLDGLRKVNKSYPSLTTKVE-ESGEHVILGTGELYLDCVMHDLRKMYSEID 617
Query: 555 TYLGPLQVAYRETILNS----------------VRATDTLDRTLGDKRHLVTVEVE---- 594
+ V + ET++ + + L++ L + V++
Sbjct: 618 IKVADPVVTFCETVVETSSLKCFAETPNKKNKITMIAEPLEKGLAEDIENEVVQITWNRK 677
Query: 595 ----------------ARPI-----ETSSVMPVIEFEYAESINEGLLKVSQEAIENGIHS 633
AR I + + +++ +++ LL +++I G
Sbjct: 678 KLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVDDTLPSEVDKALLGSVKDSIVQGFQW 737
Query: 634 ACLQGPLLGSPIQDVAITLHSLTI-----HPGTSTTMISACVSRCVQKALKKADKQVLEP 688
+GPL I++V + + H G + +A R V A A +++EP
Sbjct: 738 GTREGPLCDELIRNVKFKILDAVVAQEPLHRGGGQIIPTA--RRVVYSAFLMATPRLMEP 795
Query: 689 LMNLEVTVARDYLSPVLADLAQRRGNIQEIQTRQDNKV--VIGFVPLAEIMGYSTVLRTL 746
+EV D +S V LA+RRG++ + + + + F+P + G+ T LRT
Sbjct: 796 YYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTH 855
Query: 747 TSGSATFALELSTYQAMNPQD 767
T G A F+L + + + P D
Sbjct: 856 TQGQA-FSLSVFHHWQIVPGD 875
>gi|217272892 elongation factor Tu GTP binding domain containing 2
isoform a [Homo sapiens]
Length = 972
Score = 70.5 bits (171), Expect = 6e-12
Identities = 46/135 (34%), Positives = 71/135 (52%), Gaps = 6/135 (4%)
Query: 70 IRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITIQSAAVT 129
IRN+ + H+ GKT + ++ + + D TD + E+ERG+ I+S VT
Sbjct: 129 IRNVTLCGHLHHGKTCFVDCLIEQT-HPEIRKRYDQDLCYTDILFTEQERGVGIKSTPVT 187
Query: 130 F---DWKG--YRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQAD 184
D KG Y N++DTPGHV+F+ EV LR+ DG V DA+ GV T + + A
Sbjct: 188 VVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAV 247
Query: 185 KHNIPRICFLNKMDK 199
+ + +NK+D+
Sbjct: 248 QERLAVTVCINKIDR 262
Score = 67.8 bits (164), Expect = 4e-11
Identities = 92/441 (20%), Positives = 176/441 (39%), Gaps = 81/441 (18%)
Query: 385 FMRIYSGTIKPQLAIHNINGNCTER---------ISRLLLPFADQHVEIPSLTAGNIALT 435
F R+ SGTI + + N T + RL + A H+E+ + AGN L
Sbjct: 493 FGRVLSGTIHAGQPVKVLGENYTLEDEEDSQICTVGRLWISVARYHIEVNRVPAGNWVLI 552
Query: 436 VGLKHTATGDTIVSSKSSALAAARRAEREGEKKHRQNNEAERLLLAGVEIPEPVFFCTIE 495
G+ K++ + R E + + N + +A +E
Sbjct: 553 EGVDQPIV-------KTATITEPRGNEEAQIFRPLKFNTTSVIKIA------------VE 593
Query: 496 PPSLSKQPDLEHALKCLQREDPSLKVRLDPDSGQTVLCGMGELHIE-IIHDRIKREYGLE 554
P + S+ P + L+ + + PSL +++ +SG+ V+ G GEL+++ ++HD K ++
Sbjct: 594 PVNPSELPKMLDGLRKVNKSYPSLTTKVE-ESGEHVILGTGELYLDCVMHDLRKMYSEID 652
Query: 555 TYLGPLQVAYRETILNS----------------VRATDTLDRTLGDKRHLVTVEVE---- 594
+ V + ET++ + + L++ L + V++
Sbjct: 653 IKVADPVVTFCETVVETSSLKCFAETPNKKNKITMIAEPLEKGLAEDIENEVVQITWNRK 712
Query: 595 ----------------ARPI-----ETSSVMPVIEFEYAESINEGLLKVSQEAIENGIHS 633
AR I + + +++ +++ LL +++I G
Sbjct: 713 KLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVDDTLPSEVDKALLGSVKDSIVQGFQW 772
Query: 634 ACLQGPLLGSPIQDVAITLHSLTI-----HPGTSTTMISACVSRCVQKALKKADKQVLEP 688
+GPL I++V + + H G + +A R V A A +++EP
Sbjct: 773 GTREGPLCDELIRNVKFKILDAVVAQEPLHRGGGQIIPTA--RRVVYSAFLMATPRLMEP 830
Query: 689 LMNLEVTVARDYLSPVLADLAQRRGNIQEIQTRQDNKV--VIGFVPLAEIMGYSTVLRTL 746
+EV D +S V LA+RRG++ + + + + F+P + G+ T LRT
Sbjct: 831 YYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTH 890
Query: 747 TSGSATFALELSTYQAMNPQD 767
T G A F+L + + + P D
Sbjct: 891 TQGQA-FSLSVFHHWQIVPGD 910
>gi|94966752 elongation factor Tu GTP binding domain containing 1
isoform 2 [Homo sapiens]
Length = 1069
Score = 68.2 bits (165), Expect = 3e-11
Identities = 35/82 (42%), Positives = 47/82 (57%)
Query: 135 YRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQADKHNIPRICFL 194
Y +NLID+PGHVDF+ EV +R+ DG + V DA GV QT V RQA NI + +
Sbjct: 35 YLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVI 94
Query: 195 NKMDKTGASFKYAVESIREKLK 216
NK+D+ K+ + LK
Sbjct: 95 NKIDRLIVELKFTPQEAYSHLK 116
Score = 41.6 bits (96), Expect = 0.003
Identities = 25/105 (23%), Positives = 53/105 (50%), Gaps = 3/105 (2%)
Query: 488 PVFFCTIEPPSLSKQPDLEHALKCLQREDPSLKVRLDPDSGQTVLCGMGELHIEIIHDRI 547
P+ +EP S+ P L +K L + DP +++ L ++G+ VL GE+H++ D +
Sbjct: 565 PIVRVAVEPKHPSEMPQLVKGMKLLNQADPCVQI-LIQETGEHVLVTAGEVHLQRCLDDL 623
Query: 548 KREYG-LETYLGPLQVAYRETILNSVRATDTLDRTLGDKRHLVTV 591
K + + + + +RETI + D ++ +G ++ + +
Sbjct: 624 KERFAKIHISVSEPIIPFRETITKPPK-VDMVNEEIGKQQKVAVI 667
Score = 38.9 bits (89), Expect = 0.018
Identities = 26/110 (23%), Positives = 55/110 (50%), Gaps = 3/110 (2%)
Query: 660 GTSTTMISACVSRCVQKALKKADKQVLEPLMNLEVTVARDYLSPVLADLAQRRGNI--QE 717
G + + A + + AL+ ++++ + ++ D L V A L++R G + +E
Sbjct: 904 GPFSGQLIATMKEACRYALQVKPQRLMAAMYTCDIMATGDVLGRVYAVLSKREGRVLQEE 963
Query: 718 IQTRQDNKVVIGFVPLAEIMGYSTVLRTLTSGSATFALELSTYQAMNPQD 767
++ D ++ +P+AE G++ +R TSG A+ L S ++ + P D
Sbjct: 964 MKEGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEII-PSD 1012
>gi|4503471 eukaryotic translation elongation factor 1 alpha 1 [Homo
sapiens]
Length = 462
Score = 60.8 bits (146), Expect = 5e-09
Identities = 45/150 (30%), Positives = 69/150 (46%), Gaps = 21/150 (14%)
Query: 72 NIGIMAHIDAGKTTTTERILYYSG---------YTRSLGDVDDGDT----VTDFMAQERE 118
NI ++ H+D+GK+TTT ++Y G + + ++ G V D + ERE
Sbjct: 9 NIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERE 68
Query: 119 RGITIQSAAVTFDWKGYRVNLIDTPGHVDF-------TLEVERCLRVLDGAVAVFDASAG 171
RGITI + F+ Y V +ID PGH DF T + + + ++ V F+A
Sbjct: 69 RGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGIS 128
Query: 172 VEAQTLTVWRQADKHNIPR-ICFLNKMDKT 200
QT A + + I +NKMD T
Sbjct: 129 KNGQTREHALLAYTLGVKQLIVGVNKMDST 158
>gi|239757543 PREDICTED: similar to eukaryotic translation
elongation factor 1 alpha 2 [Homo sapiens]
Length = 444
Score = 60.5 bits (145), Expect = 6e-09
Identities = 44/154 (28%), Positives = 71/154 (46%), Gaps = 21/154 (13%)
Query: 72 NIGIMAHIDAGKTTTTERILYYSG---------YTRSLGDVDDGDT----VTDFMAQERE 118
NI ++ H+D+GK+TTT ++Y G + + ++ G V D + ERE
Sbjct: 9 NIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERE 68
Query: 119 RGITIQSAAVTFDWKGYRVNLIDTPGHVDF-------TLEVERCLRVLDGAVAVFDASAG 171
RGITI + F+ Y + +ID PGH DF T + + + ++ V F+A
Sbjct: 69 RGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGIS 128
Query: 172 VEAQTLTVWRQADKHNIPR-ICFLNKMDKTGASF 204
QT A + + I +NKMD T ++
Sbjct: 129 KNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAY 162
>gi|4503475 eukaryotic translation elongation factor 1 alpha 2 [Homo
sapiens]
Length = 463
Score = 60.5 bits (145), Expect = 6e-09
Identities = 44/154 (28%), Positives = 71/154 (46%), Gaps = 21/154 (13%)
Query: 72 NIGIMAHIDAGKTTTTERILYYSG---------YTRSLGDVDDGDT----VTDFMAQERE 118
NI ++ H+D+GK+TTT ++Y G + + ++ G V D + ERE
Sbjct: 9 NIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERE 68
Query: 119 RGITIQSAAVTFDWKGYRVNLIDTPGHVDF-------TLEVERCLRVLDGAVAVFDASAG 171
RGITI + F+ Y + +ID PGH DF T + + + ++ V F+A
Sbjct: 69 RGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGIS 128
Query: 172 VEAQTLTVWRQADKHNIPR-ICFLNKMDKTGASF 204
QT A + + I +NKMD T ++
Sbjct: 129 KNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAY 162
>gi|223555963 Hsp70 subfamily B suppressor 1-like protein isoform 2
[Homo sapiens]
Length = 642
Score = 52.0 bits (123), Expect = 2e-06
Identities = 35/116 (30%), Positives = 52/116 (44%), Gaps = 13/116 (11%)
Query: 69 KIRNIGIMAHIDAGKTTTTERILY------------YSGYTRSLGDVDDGDT-VTDFMAQ 115
++ N+ ++ H+DAGK+T +LY Y ++ G V D +
Sbjct: 217 QLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGE 276
Query: 116 ERERGITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAG 171
ERERG+T+ F+ + L+D PGH DF + D AV V DAS G
Sbjct: 277 ERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRG 332
>gi|5729864 Hsp70 subfamily B suppressor 1-like protein isoform 1
[Homo sapiens]
Length = 684
Score = 52.0 bits (123), Expect = 2e-06
Identities = 35/116 (30%), Positives = 52/116 (44%), Gaps = 13/116 (11%)
Query: 69 KIRNIGIMAHIDAGKTTTTERILY------------YSGYTRSLGDVDDGDT-VTDFMAQ 115
++ N+ ++ H+DAGK+T +LY Y ++ G V D +
Sbjct: 259 QLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGE 318
Query: 116 ERERGITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAG 171
ERERG+T+ F+ + L+D PGH DF + D AV V DAS G
Sbjct: 319 ERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRG 374
>gi|34147630 Tu translation elongation factor, mitochondrial
precursor [Homo sapiens]
Length = 455
Score = 52.0 bits (123), Expect = 2e-06
Identities = 40/132 (30%), Positives = 59/132 (44%), Gaps = 11/132 (8%)
Query: 72 NIGIMAHIDAGKTTTTERI--LYYSGYTRSLGDVDDGDTVTDFMAQERERGITIQSAAVT 129
N+G + H+D GKTT T I + G ++ D + ER RGITI +A V
Sbjct: 62 NVGTIGHVDHGKTTLTAAITKILAEGGGAKFKKYEEIDNAPE----ERARGITINAAHVE 117
Query: 130 FDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQT---LTVWRQADKH 186
+ D PGH D+ + LDG + V A+ G QT L + RQ
Sbjct: 118 YSTAARHYAHTDCPGHADYVKNMITGTAPLDGCILVVAANDGPMPQTREHLLLARQIGVE 177
Query: 187 NIPRICFLNKMD 198
++ + ++NK D
Sbjct: 178 HV--VVYVNKAD 187
>gi|53729339 mitochondrial translational initiation factor 2
precursor [Homo sapiens]
Length = 727
Score = 49.3 bits (116), Expect = 1e-05
Identities = 60/232 (25%), Positives = 89/232 (38%), Gaps = 52/232 (22%)
Query: 73 IGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITIQSAAVTFDW 132
+ IM H+D GKTT ++ + V+ G GIT A
Sbjct: 183 VTIMGHVDHGKTTLLDKFR-----KTQVAAVETG-------------GITQHIGAFLVSL 224
Query: 133 -KGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQADKHNIPRI 191
G ++ +DTPGH F+ R +V D V V A GV QT+ + A +P I
Sbjct: 225 PSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPII 284
Query: 192 CFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVMKEKLLWNCNSN 251
+NK DK E+ EK+K + L DVV ++
Sbjct: 285 LAVNKCDK--------AEADPEKVKKELL--------------AYDVVCEDY-------- 314
Query: 252 DGKDFERKPLLEMNDPEL--LKETTEARNALIEQVADLDDEFADLVLEEFSE 301
G D + P+ + L L E T A ++E AD + V+E F++
Sbjct: 315 -GGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVIESFTD 365
>gi|53729337 mitochondrial translational initiation factor 2
precursor [Homo sapiens]
Length = 727
Score = 49.3 bits (116), Expect = 1e-05
Identities = 60/232 (25%), Positives = 89/232 (38%), Gaps = 52/232 (22%)
Query: 73 IGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITIQSAAVTFDW 132
+ IM H+D GKTT ++ + V+ G GIT A
Sbjct: 183 VTIMGHVDHGKTTLLDKFR-----KTQVAAVETG-------------GITQHIGAFLVSL 224
Query: 133 -KGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQADKHNIPRI 191
G ++ +DTPGH F+ R +V D V V A GV QT+ + A +P I
Sbjct: 225 PSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPII 284
Query: 192 CFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVMKEKLLWNCNSN 251
+NK DK E+ EK+K + L DVV ++
Sbjct: 285 LAVNKCDK--------AEADPEKVKKELL--------------AYDVVCEDY-------- 314
Query: 252 DGKDFERKPLLEMNDPEL--LKETTEARNALIEQVADLDDEFADLVLEEFSE 301
G D + P+ + L L E T A ++E AD + V+E F++
Sbjct: 315 -GGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVIESFTD 365
>gi|194018522 G1 to S phase transition 1 isoform 3 [Homo sapiens]
Length = 499
Score = 44.3 bits (103), Expect = 4e-04
Identities = 45/186 (24%), Positives = 74/186 (39%), Gaps = 25/186 (13%)
Query: 55 DIKSLHSIINPPIAKIR---NIGIMAHIDAGKTTTTERILYYSG---------YTRSLGD 102
+I S++ PP A + N+ + H+DAGK+T +I+Y +G Y R +
Sbjct: 56 EIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKE 115
Query: 103 VDDG----DTVTDFMAQERERGITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRV 158
+ D +ER++G T++ F+ + ++D PGH F +
Sbjct: 116 KNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQ 175
Query: 159 LDGAVAVFDASAGVEAQTLTVWRQADKHNI--------PRICFLNKMDKTGASF-KYAVE 209
D AV V A G Q +H + I +NKMD ++ E
Sbjct: 176 ADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYE 235
Query: 210 SIREKL 215
+EKL
Sbjct: 236 ECKEKL 241
>gi|194097354 G1 to S phase transition 1 isoform 2 [Homo sapiens]
Length = 636
Score = 44.3 bits (103), Expect = 4e-04
Identities = 45/186 (24%), Positives = 74/186 (39%), Gaps = 25/186 (13%)
Query: 55 DIKSLHSIINPPIAKIR---NIGIMAHIDAGKTTTTERILYYSG---------YTRSLGD 102
+I S++ PP A + N+ + H+DAGK+T +I+Y +G Y R +
Sbjct: 193 EIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKE 252
Query: 103 VDDG----DTVTDFMAQERERGITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRV 158
+ D +ER++G T++ F+ + ++D PGH F +
Sbjct: 253 KNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQ 312
Query: 159 LDGAVAVFDASAGVEAQTLTVWRQADKHNI--------PRICFLNKMDKTGASF-KYAVE 209
D AV V A G Q +H + I +NKMD ++ E
Sbjct: 313 ADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYE 372
Query: 210 SIREKL 215
+EKL
Sbjct: 373 ECKEKL 378
>gi|194018520 G1 to S phase transition 1 isoform 1 [Homo sapiens]
Length = 637
Score = 44.3 bits (103), Expect = 4e-04
Identities = 45/186 (24%), Positives = 74/186 (39%), Gaps = 25/186 (13%)
Query: 55 DIKSLHSIINPPIAKIR---NIGIMAHIDAGKTTTTERILYYSG---------YTRSLGD 102
+I S++ PP A + N+ + H+DAGK+T +I+Y +G Y R +
Sbjct: 194 EIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKE 253
Query: 103 VDDG----DTVTDFMAQERERGITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRV 158
+ D +ER++G T++ F+ + ++D PGH F +
Sbjct: 254 KNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQ 313
Query: 159 LDGAVAVFDASAGVEAQTLTVWRQADKHNI--------PRICFLNKMDKTGASF-KYAVE 209
D AV V A G Q +H + I +NKMD ++ E
Sbjct: 314 ADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYE 373
Query: 210 SIREKL 215
+EKL
Sbjct: 374 ECKEKL 379
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 44.3 bits (103), Expect = 4e-04
Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 8/131 (6%)
Query: 73 IGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITIQSAAV-TFD 131
I ++ H+D GKT +++ + G + T+ + I Q+ + FD
Sbjct: 634 ICVLGHVDTGKTKILDKLRHTHVQDGEAGGITQQIGATNVPLE----AINEQTKMIKNFD 689
Query: 132 WKGYRVN---LIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQADKHNI 188
+ R+ +IDTPGH F+ R + D A+ V D G+E QT+
Sbjct: 690 RENVRIPGMLIIDTPGHESFSNLRNRGSSLCDIAILVVDIMHGLEPQTIESINLLKSKKC 749
Query: 189 PRICFLNKMDK 199
P I LNK+D+
Sbjct: 750 PFIVALNKIDR 760
>gi|46094014 peptide chain release factor 3 [Homo sapiens]
Length = 628
Score = 42.0 bits (97), Expect = 0.002
Identities = 44/186 (23%), Positives = 74/186 (39%), Gaps = 25/186 (13%)
Query: 55 DIKSLHSIINP---PIAKIRNIGIMAHIDAGKTTTTERILYYSG---------YTRSLGD 102
+I+ S+I P P + N+ + H+DAGK+T +I++ +G Y R +
Sbjct: 185 EIRKSKSVIVPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDKRTLEKYEREAKE 244
Query: 103 VDDG----DTVTDFMAQERERGITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRV 158
+ D +ER++G T++ F+ + ++D PGH F +
Sbjct: 245 KNRETWYLSWALDTNQEERDKGKTVEVGRAYFETERKHFTILDAPGHKSFVPNMIGGASQ 304
Query: 159 LDGAVAVFDASAGVEAQTLTVWRQADKHNI--------PRICFLNKMDKTGASFKY-AVE 209
D AV V A G Q +H + I +NKMD ++ E
Sbjct: 305 ADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSIERYE 364
Query: 210 SIREKL 215
+EKL
Sbjct: 365 ECKEKL 370
>gi|54607086 eukaryotic elongation factor,
selenocysteine-tRNA-specific [Homo sapiens]
Length = 596
Score = 37.4 bits (85), Expect = 0.054
Identities = 33/130 (25%), Positives = 52/130 (40%), Gaps = 36/130 (27%)
Query: 72 NIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITI-------- 123
N+G++ HID+GKT R L + T + D Q RERGIT+
Sbjct: 9 NVGVLGHIDSGKTALA-RALSTTASTAAF----------DKQPQSRERGITLDLGFSCFS 57
Query: 124 --------------QSAAVTFDWKG---YRVNLIDTPGHVDFTLEVERCLRVLDGAVAVF 166
Q+A G +V L+D PGH + +++D + V
Sbjct: 58 VPLPARLRSSLPEFQAAPEAEPEPGEPLLQVTLVDCPGHASLIRTIIGGAQIIDLMMLVI 117
Query: 167 DASAGVEAQT 176
D + G++ Q+
Sbjct: 118 DVTKGMQTQS 127
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 31.6 bits (70), Expect = 3.0
Identities = 21/73 (28%), Positives = 39/73 (53%), Gaps = 3/73 (4%)
Query: 242 EKLLWNCNSNDGKDFERKPLLEMNDPELLKETTEARNALIEQVADLDDEFADLVLEEFSE 301
EK+ N +S K+ ER+ +E + E +E +AR+ EQ ++D E EE +
Sbjct: 824 EKIAKNLDSEKEKELERQARIEASLREREREVQKARS---EQTKEIDREREQHKREEAIQ 880
Query: 302 NFDLLPAEKLQTA 314
NF L ++ ++++
Sbjct: 881 NFKALLSDMVRSS 893
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 31.6 bits (70), Expect = 3.0
Identities = 21/73 (28%), Positives = 39/73 (53%), Gaps = 3/73 (4%)
Query: 242 EKLLWNCNSNDGKDFERKPLLEMNDPELLKETTEARNALIEQVADLDDEFADLVLEEFSE 301
EK+ N +S K+ ER+ +E + E +E +AR+ EQ ++D E EE +
Sbjct: 845 EKIAKNLDSEKEKELERQARIEASLREREREVQKARS---EQTKEIDREREQHKREEAIQ 901
Query: 302 NFDLLPAEKLQTA 314
NF L ++ ++++
Sbjct: 902 NFKALLSDMVRSS 914
>gi|4506365 RAB2A, member RAS oncogene family [Homo sapiens]
Length = 212
Score = 30.8 bits (68), Expect = 5.0
Identities = 22/83 (26%), Positives = 33/83 (39%), Gaps = 4/83 (4%)
Query: 120 GITIQSAAVTFDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTV 179
G+ + +T D K ++ + DT G F R GA+ V+D + LT
Sbjct: 40 GVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTT 99
Query: 180 W----RQADKHNIPRICFLNKMD 198
W RQ N+ + NK D
Sbjct: 100 WLEDARQHSNSNMVIMLIGNKSD 122
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,893,726
Number of Sequences: 37866
Number of extensions: 1216681
Number of successful extensions: 3067
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2983
Number of HSP's gapped (non-prelim): 49
length of query: 779
length of database: 18,247,518
effective HSP length: 110
effective length of query: 669
effective length of database: 14,082,258
effective search space: 9421030602
effective search space used: 9421030602
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.