Guide to the Human Genome
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Search of human proteins with 19923345

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923345 RNA binding motif protein 12 [Homo sapiens]
         (932 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923345 RNA binding motif protein 12 [Homo sapiens]              1919   0.0  
gi|23510462 RNA binding motif protein 12 [Homo sapiens]              1919   0.0  
gi|118722349 RNA binding motif protein 12B [Homo sapiens]             199   1e-50
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   101   4e-21
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   101   4e-21
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   101   4e-21
gi|126352608 elastin isoform e precursor [Homo sapiens]                95   3e-19
gi|126352322 elastin isoform c precursor [Homo sapiens]                95   3e-19
gi|126352700 elastin isoform b precursor [Homo sapiens]                95   3e-19
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]     95   3e-19
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    94   8e-19
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    94   8e-19
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]        92   2e-18
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]        92   2e-18
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      91   4e-18
gi|148470406 heterogeneous nuclear ribonucleoprotein F [Homo sap...    90   9e-18
gi|148470404 heterogeneous nuclear ribonucleoprotein F [Homo sap...    90   9e-18
gi|148470402 heterogeneous nuclear ribonucleoprotein F [Homo sap...    90   9e-18
gi|148470400 heterogeneous nuclear ribonucleoprotein F [Homo sap...    90   9e-18
gi|148470397 heterogeneous nuclear ribonucleoprotein F [Homo sap...    90   9e-18
gi|4826760 heterogeneous nuclear ribonucleoprotein F [Homo sapiens]    90   9e-18
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      89   2e-17
gi|126352446 elastin isoform d precursor [Homo sapiens]                89   2e-17
gi|126352440 elastin isoform a precursor [Homo sapiens]                89   2e-17
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                89   2e-17
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]           87   6e-17
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]        87   9e-17
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho...    85   4e-16
gi|74099697 heterogeneous nuclear ribonucleoprotein H2 [Homo sap...    82   2e-15
gi|9624998 heterogeneous nuclear ribonucleoprotein H2 [Homo sapi...    82   2e-15

>gi|19923345 RNA binding motif protein 12 [Homo sapiens]
          Length = 932

 Score = 1919 bits (4972), Expect = 0.0
 Identities = 932/932 (100%), Positives = 932/932 (100%)

Query: 1   MAVVIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIVGGELGEAFIVFATDEDARLGMMRT 60
           MAVVIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIVGGELGEAFIVFATDEDARLGMMRT
Sbjct: 1   MAVVIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIVGGELGEAFIVFATDEDARLGMMRT 60

Query: 61  GGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANLDIPPANASRSGPPPSSGMSSRVNLP 120
           GGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANLDIPPANASRSGPPPSSGMSSRVNLP
Sbjct: 61  GGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANLDIPPANASRSGPPPSSGMSSRVNLP 120

Query: 121 TTVSNFNNPSPSVVTATTSVHESNKNIQTFSTASVGTAPPNMGASFGSPTFSSTVPSTAS 180
           TTVSNFNNPSPSVVTATTSVHESNKNIQTFSTASVGTAPPNMGASFGSPTFSSTVPSTAS
Sbjct: 121 TTVSNFNNPSPSVVTATTSVHESNKNIQTFSTASVGTAPPNMGASFGSPTFSSTVPSTAS 180

Query: 181 PMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLPP 240
           PMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLPP
Sbjct: 181 PMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLPP 240

Query: 241 MSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNPIQMNSQSSVKPLPIN 300
           MSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNPIQMNSQSSVKPLPIN
Sbjct: 241 MSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNPIQMNSQSSVKPLPIN 300

Query: 301 PDDLYVSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEAL 360
           PDDLYVSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEAL
Sbjct: 301 PDDLYVSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEAL 360

Query: 361 KRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMGPSGQTHPPPQTLPRSKSPSGQKRS 420
           KRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMGPSGQTHPPPQTLPRSKSPSGQKRS
Sbjct: 361 KRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMGPSGQTHPPPQTLPRSKSPSGQKRS 420

Query: 421 RSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRN 480
           RSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRN
Sbjct: 421 RSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRN 480

Query: 481 EADYKAALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQREMILNPEGDVN 540
           EADYKAALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQREMILNPEGDVN
Sbjct: 481 EADYKAALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQREMILNPEGDVN 540

Query: 541 SAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARK 600
           SAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARK
Sbjct: 541 SAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARK 600

Query: 601 SERLHRKKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPAVPGMPNAGLPGV 660
           SERLHRKKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPAVPGMPNAGLPGV
Sbjct: 601 SERLHRKKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPAVPGMPNAGLPGV 660

Query: 661 GLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPP 720
           GLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPP
Sbjct: 661 GLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPP 720

Query: 721 FNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLS 780
           FNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLS
Sbjct: 721 FNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLS 780

Query: 781 GPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHI 840
           GPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHI
Sbjct: 781 GPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHI 840

Query: 841 GGPPGFASSSGKPGPTVIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEA 900
           GGPPGFASSSGKPGPTVIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEA
Sbjct: 841 GGPPGFASSSGKPGPTVIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEA 900

Query: 901 MVAFESRDEATAAVIDLNDRPIGSRKVKLVLG 932
           MVAFESRDEATAAVIDLNDRPIGSRKVKLVLG
Sbjct: 901 MVAFESRDEATAAVIDLNDRPIGSRKVKLVLG 932


>gi|23510462 RNA binding motif protein 12 [Homo sapiens]
          Length = 932

 Score = 1919 bits (4972), Expect = 0.0
 Identities = 932/932 (100%), Positives = 932/932 (100%)

Query: 1   MAVVIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIVGGELGEAFIVFATDEDARLGMMRT 60
           MAVVIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIVGGELGEAFIVFATDEDARLGMMRT
Sbjct: 1   MAVVIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIVGGELGEAFIVFATDEDARLGMMRT 60

Query: 61  GGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANLDIPPANASRSGPPPSSGMSSRVNLP 120
           GGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANLDIPPANASRSGPPPSSGMSSRVNLP
Sbjct: 61  GGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANLDIPPANASRSGPPPSSGMSSRVNLP 120

Query: 121 TTVSNFNNPSPSVVTATTSVHESNKNIQTFSTASVGTAPPNMGASFGSPTFSSTVPSTAS 180
           TTVSNFNNPSPSVVTATTSVHESNKNIQTFSTASVGTAPPNMGASFGSPTFSSTVPSTAS
Sbjct: 121 TTVSNFNNPSPSVVTATTSVHESNKNIQTFSTASVGTAPPNMGASFGSPTFSSTVPSTAS 180

Query: 181 PMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLPP 240
           PMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLPP
Sbjct: 181 PMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLPP 240

Query: 241 MSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNPIQMNSQSSVKPLPIN 300
           MSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNPIQMNSQSSVKPLPIN
Sbjct: 241 MSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNPIQMNSQSSVKPLPIN 300

Query: 301 PDDLYVSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEAL 360
           PDDLYVSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEAL
Sbjct: 301 PDDLYVSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEAL 360

Query: 361 KRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMGPSGQTHPPPQTLPRSKSPSGQKRS 420
           KRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMGPSGQTHPPPQTLPRSKSPSGQKRS
Sbjct: 361 KRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMGPSGQTHPPPQTLPRSKSPSGQKRS 420

Query: 421 RSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRN 480
           RSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRN
Sbjct: 421 RSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRN 480

Query: 481 EADYKAALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQREMILNPEGDVN 540
           EADYKAALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQREMILNPEGDVN
Sbjct: 481 EADYKAALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQREMILNPEGDVN 540

Query: 541 SAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARK 600
           SAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARK
Sbjct: 541 SAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARK 600

Query: 601 SERLHRKKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPAVPGMPNAGLPGV 660
           SERLHRKKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPAVPGMPNAGLPGV
Sbjct: 601 SERLHRKKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPAVPGMPNAGLPGV 660

Query: 661 GLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPP 720
           GLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPP
Sbjct: 661 GLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPP 720

Query: 721 FNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLS 780
           FNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLS
Sbjct: 721 FNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLS 780

Query: 781 GPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHI 840
           GPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHI
Sbjct: 781 GPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHI 840

Query: 841 GGPPGFASSSGKPGPTVIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEA 900
           GGPPGFASSSGKPGPTVIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEA
Sbjct: 841 GGPPGFASSSGKPGPTVIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEA 900

Query: 901 MVAFESRDEATAAVIDLNDRPIGSRKVKLVLG 932
           MVAFESRDEATAAVIDLNDRPIGSRKVKLVLG
Sbjct: 901 MVAFESRDEATAAVIDLNDRPIGSRKVKLVLG 932


>gi|118722349 RNA binding motif protein 12B [Homo sapiens]
          Length = 1001

 Score =  199 bits (505), Expect = 1e-50
 Identities = 120/348 (34%), Positives = 195/348 (56%), Gaps = 19/348 (5%)

Query: 295 KPLPINPDDLYVSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQ 354
           K  P+  ++ Y+ + G+P+   E+DVR FF GL VD V  LK H GRNNG+ +VKF S  
Sbjct: 146 KTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCV 205

Query: 355 DTFEALKRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMGPSGQTHPPPQTL------ 408
           D    LK +R  M  R++EV   +E+QW+  GG+   + ++    + H PP+ +      
Sbjct: 206 DASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGNAVKEGDVLRRSEEHSPPRGINDRHFR 265

Query: 409 --PRSKSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGP 466
               SKSP   +R+RSRSP   GF V+LK L    + + + +FF+  D+ ++ I   Y  
Sbjct: 266 KRSHSKSP---RRTRSRSP--LGFYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKD 320

Query: 467 NGKATGEGFVEFRNEADYKAALCRHKQYMGNRFIQVHPITKKGMLEKIDMI-RKRLQNFS 525
             + T   FV F+   DY  AL  HK  +  R + + PI++K ML+ I    +KR  +  
Sbjct: 321 ENR-TRYAFVMFKTLKDYNTALSLHKTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLE 379

Query: 526 YDQREMI---LNPEGDVNSAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNG 582
            D+   +    + EG+ +  K+C +I N PF +TK++V +F     + E+ +++L D+ G
Sbjct: 380 RDRPGHVSQKYSQEGN-SGQKLCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKG 438

Query: 583 QGLGQALVQFKNEDDARKSERLHRKKLNGREAFVHVVTLEDMREIEKN 630
            GLG+ALV+FK+E+ A K+ERL+R++  G E  + +++   ++E   N
Sbjct: 439 VGLGEALVKFKSEEQAMKAERLNRRRFLGTEVLLRLISEAQIQEFGVN 486



 Score =  129 bits (325), Expect = 1e-29
 Identities = 63/87 (72%), Positives = 72/87 (82%)

Query: 1  MAVVIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIVGGELGEAFIVFATDEDARLGMMRT 60
          MAVVIRL GLP +AG +DIRHFF+GLTIPDGGVHI+GGE+GEAFI+FATDEDAR  + R+
Sbjct: 1  MAVVIRLLGLPFIAGPVDIRHFFTGLTIPDGGVHIIGGEIGEAFIIFATDEDARRAISRS 60

Query: 61 GGTIKGSKVTLLLSSKTEMQNMIELSR 87
          GG IK S V L LSSK EMQ  IE+ R
Sbjct: 61 GGFIKDSSVELFLSSKAEMQKTIEMKR 87



 Score =  103 bits (256), Expect = 1e-21
 Identities = 49/88 (55%), Positives = 67/88 (76%), Gaps = 2/88 (2%)

Query: 844  PGFASSSGKPGPTVIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVA 903
            P     SG+  P  IK+ N+PF  +++EILDFF+GY++IP SV ++YNE+G+PTGEA+VA
Sbjct: 915  PKINCGSGRVTP--IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVA 972

Query: 904  FESRDEATAAVIDLNDRPIGSRKVKLVL 931
              + +EA AA+ DLNDRP+G RKVKL L
Sbjct: 973  MINYNEAMAAIKDLNDRPVGPRKVKLTL 1000



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 53/216 (24%), Positives = 91/216 (42%), Gaps = 17/216 (7%)

Query: 289 NSQSSVKPLPINPDDLYVSVHGMPFSAMENDVRDFFHG--LRVDAVHLLKDHVGRNNGNG 346
           +S+S  +    +P   YV +  +  S  E D+R+FF G  L  + +  L     R     
Sbjct: 269 HSKSPRRTRSRSPLGFYVHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENRTR-YA 327

Query: 347 LVKFLSPQDTFEALKRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMGPSGQTHPPPQ 406
            V F + +D   AL  ++ ++  R V + P + +Q +        K+  G   +  P   
Sbjct: 328 FVMFKTLKDYNTALSLHKTVLQYRPVHIDPISRKQMLKFIARYE-KKRSGSLERDRPGHV 386

Query: 407 TLPRS-KSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYG 465
           +   S +  SGQK            C+Y++  PF+     V  FF    + ED IY+ Y 
Sbjct: 387 SQKYSQEGNSGQK-----------LCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYD 435

Query: 466 PNGKATGEGFVEFRNEAD-YKAALCRHKQYMGNRFI 500
             G   GE  V+F++E    KA     ++++G   +
Sbjct: 436 DKGVGLGEALVKFKSEEQAMKAERLNRRRFLGTEVL 471



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 81/384 (21%), Positives = 148/384 (38%), Gaps = 54/384 (14%)

Query: 310 GMPFSAMENDVRDFFHGLRV--DAVHLLKDHVGRNNGNGLVKFLSPQDTFEALKRNRMLM 367
           G+PF A   D+R FF GL +    VH+    +G   G   + F + +D   A+ R+   +
Sbjct: 9   GLPFIAGPVDIRHFFTGLTIPDGGVHI----IGGEIGEAFIIFATDEDARRAISRSGGFI 64

Query: 368 IQRYVEV-------------SPATERQWVAAGGHIT------------FKQNMGPSGQTH 402
               VE+                T+R      G  T             K+    SG   
Sbjct: 65  KDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNSGYGS 124

Query: 403 PPPQT--LPRSKSPSGQKRSRSRSPHEA-GFCVYLKGLPFEAENKHVIDFFKKLDIVEDS 459
              Q      + +  G  R R   P +A    ++L+GLP+      V  FF  L +  D 
Sbjct: 125 SINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCV--DG 182

Query: 460 IYIAYGPNGKATGEGFVEFRNEADYKAALCRHKQYMGNRFIQVHPITKKGMLE------- 512
           +      +G+  G+  V+F +  D    L  H+ +MG+RFI+V   +++  +E       
Sbjct: 183 VIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGNAVK 242

Query: 513 KIDMIRKR--------LQNFSYDQREMILNPEGDVNSAKV--CAHITNIPFSITKMDVLQ 562
           + D++R+         + +  + +R    +P    + + +    H+ N+  SI + D+  
Sbjct: 243 EGDVLRRSEEHSPPRGINDRHFRKRSHSKSPRRTRSRSPLGFYVHLKNLSLSIDERDLRN 302

Query: 563 FLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHRKKLNGREAFVHVVTLE 622
           F  G  + +  +  L  +  +    A V FK   D   +  LH+  L  R   +  ++ +
Sbjct: 303 FFRGTDLTDEQIRFLYKDENR-TRYAFVMFKTLKDYNTALSLHKTVLQYRPVHIDPISRK 361

Query: 623 DMREIEKNPPAQGKKGLKMPVPGN 646
            M +       +    L+   PG+
Sbjct: 362 QMLKFIARYEKKRSGSLERDRPGH 385



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 54/239 (22%), Positives = 93/239 (38%), Gaps = 50/239 (20%)

Query: 432 VYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAALCRH 491
           + L GLPF A    +  FF  L I +  ++I     G   GE F+ F  + D + A+ R 
Sbjct: 5   IRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRAISRS 60

Query: 492 KQYMGNRFIQVHPITKKGMLEKIDMIR----------------KRLQNFSYDQREMILNP 535
             ++ +  +++   +K  M + I+M R                  L NF    +E   N 
Sbjct: 61  GGFIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNS 120

Query: 536 ------------------EGDVNSAKV--------CAHITNIPFSITKMDVLQFLEGIPV 569
                              G++   K            +  +P+ + + DV  F  G+ V
Sbjct: 121 GYGSSINQDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCV 180

Query: 570 DENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHRKKLNGREAFVHVVTLEDMREIE 628
           D   V  L  ++G+  G A+V+F +  DA    + HR  +  R  F+ V+   + + IE
Sbjct: 181 D--GVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSR--FIEVMQGSEQQWIE 235



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 23/67 (34%), Positives = 38/67 (56%), Gaps = 1/67 (1%)

Query: 848 SSSGKPGPTV-IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFES 906
           S  G  G  + I ++N PF V+  E+  FF  + +    + L Y++KG+  GEA+V F+S
Sbjct: 391 SQEGNSGQKLCIYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKS 450

Query: 907 RDEATAA 913
            ++A  A
Sbjct: 451 EEQAMKA 457



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 32/104 (30%), Positives = 44/104 (42%), Gaps = 14/104 (13%)

Query: 386 GGHITF-KQNMGPSGQTHPPPQTLPRSKSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENK 444
           GG   F K NMG    + P  + +P  K   G  R            + +  LPF+A   
Sbjct: 893 GGKFDFGKHNMG----SFPEGRFMPDPKINCGSGRVTP---------IKIMNLPFKANVN 939

Query: 445 HVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAAL 488
            ++DFF    I+ DS+ I Y   G  TGE  V   N  +  AA+
Sbjct: 940 EILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAI 983



 Score = 37.7 bits (86), Expect = 0.050
 Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 2/58 (3%)

Query: 306 VSVHGMPFSAMENDVRDFFHGLRV--DAVHLLKDHVGRNNGNGLVKFLSPQDTFEALK 361
           + +  +PF A  N++ DFFHG R+  D+V +  +  G   G  +V  ++  +   A+K
Sbjct: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIK 984



 Score = 35.8 bits (81), Expect = 0.19
 Identities = 15/58 (25%), Positives = 31/58 (53%), Gaps = 4/58 (6%)

Query: 544 VCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKS 601
           V   +  +PF    +D+  F  G+ + +  VH++    G  +G+A + F  ++DAR++
Sbjct: 3   VVIRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRA 56



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 22/54 (40%), Positives = 31/54 (57%), Gaps = 4/54 (7%)

Query: 7   LQGLPIVAGTMDIRHFFSGLTIPDGGV---HIVGGELGEAFIVFATDEDARLGM 57
           L+GLP +    D+R FFSGL + DG +   H  G   G+A + FA+  DA  G+
Sbjct: 159 LRGLPYLVNEDDVRVFFSGLCV-DGVIFLKHHDGRNNGDAIVKFASCVDASGGL 211



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 18/75 (24%), Positives = 37/75 (49%), Gaps = 1/75 (1%)

Query: 525 SYDQREMILNPEGDVNSAKVCA-HITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQ 583
           S+ +   + +P+ +  S +V    I N+PF     ++L F  G  +  ++V +  +  G 
Sbjct: 905 SFPEGRFMPDPKINCGSGRVTPIKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGL 964

Query: 584 GLGQALVQFKNEDDA 598
             G+A+V   N ++A
Sbjct: 965 PTGEAIVAMINYNEA 979


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 1691

 Score =  101 bits (251), Expect = 4e-21
 Identities = 97/247 (39%), Positives = 110/247 (44%), Gaps = 49/247 (19%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMP----NAGLPGVGLPSAGLPGA-GLPSTGLPGSAITSA 685
           P  +G  G  +  PG P +PG P    + GLPG      GLPG  GLP  G+PGS     
Sbjct: 649 PGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPG----DPGLPGQPGLP--GIPGSK-GEP 701

Query: 686 GLPGAGMPSA----GIPSAGGEEHAFLTVG--SKEANNGPPFNFPGNFG--GSNAFGPPI 737
           G+PG G+P      G P   G   A  T G    E   GPP  FPG  G  G    GPP 
Sbjct: 702 GIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPP-GFPGPKGEPGFALPGPPG 760

Query: 738 PP--PGLGG--GAFGDAR-PGMPSV-GNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQN 791
           PP  PG  G  G  GD   PG P   G +GL GL         GP    GP+G       
Sbjct: 761 PPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP--------GPKGDVGPNG------- 805

Query: 792 FGNGPGSLGGP--PGFG-SGPPGLGSAPGHLGGPPAFG-PGPGPGPGPGPIHIGGPPGFA 847
               PG +G P  PG G  GPPG    PG +G P   G PG    PGP  + + GPPG  
Sbjct: 806 ---QPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGER 862

Query: 848 SSSGKPG 854
            S G PG
Sbjct: 863 GSPGIPG 869



 Score = 97.8 bits (242), Expect = 4e-20
 Identities = 103/268 (38%), Positives = 113/268 (42%), Gaps = 54/268 (20%)

Query: 631  PPAQGKKGLKMP--VPGNPAVPGMP-------NAGLPGVGLPSAGLPGA----GLPS-TG 676
            P  QG +G   P  VPG P  PG+P       + G+  +GLP  GLPG     GLP   G
Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLP--GLPGPKGEPGLPGYPG 1092

Query: 677  LPG--SAITSAGLPGA-GMPSA-GIPSAGGEEHAFLTVGSKEANNGPPFN-----FPGNF 727
             PG   ++   GLPG  G P A G P   G        G K  + GPP N      PG  
Sbjct: 1093 NPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS-GPPGNPGLPGEPGPV 1151

Query: 728  GGSNAFGPPIPP--------PGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNL 779
            GG    G P PP         G+ G A     PG P  GN G PGL    PG       L
Sbjct: 1152 GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL----PG-------L 1200

Query: 780  SGPSGFGGGPQNFGNGPGSLG--GPPGFGS-----GPPGLGSAPGHLGGPPAFGPGPGPG 832
            SG  G GG P   GN PG  G  G PGF       GPPG   +PG     P   PGP   
Sbjct: 1201 SGQKGDGGLPGIPGN-PGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGP 1259

Query: 833  PG-PGPIHIGGPPGFASSSGKPGPTVIK 859
            PG PGP    G PG     G PG   IK
Sbjct: 1260 PGRPGPTGFQGLPGPEGPPGLPGNGGIK 1287



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 99/293 (33%), Positives = 115/293 (39%), Gaps = 79/293 (26%)

Query: 631  PPAQGKKGLK-MPVPGNPAVPGMPNA-GLPGV-GLPSA-GLPGA-GLPSTGLPGSAITSA 685
            P   G  GL  + V G P  PG+P   G PG+ G+P   G PG  GL   G PG    S 
Sbjct: 807  PGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGER-GSP 865

Query: 686  GLPGAGMP-----SAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPP- 739
            G+PGA  P     S G+P   G                    FPG  G     GPP PP 
Sbjct: 866  GIPGAPGPIGPPGSPGLPGKAGAS-----------------GFPGTKGEMGMMGPPGPPG 908

Query: 740  ----------PGLGGGAFGDARPGMP-------SVGNSGLPG---------LGLD----V 769
                      PGL G      +PG+P       S G  GLPG         LG       
Sbjct: 909  PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGE 968

Query: 770  PGFGGGPNNLSGPSGFGGGPQNFG----NGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAF 825
            PG  G P  +SGP G+ G P + G    +G   L GPPG   G PGL   PG +G P   
Sbjct: 969  PGLPGIPG-VSGPKGYQGLPGDPGQPGLSGQPGLPGPPG-PKGNPGLPGQPGLIGPPGLK 1026

Query: 826  G-------PGPG-----PGPGPGPIHIGGP--PGFASSSGKPGPTVIKVQNMP 864
            G       PGP      PGP   P   G P  PG     G PG + I +  +P
Sbjct: 1027 GTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLP 1079



 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 110/335 (32%), Positives = 127/335 (37%), Gaps = 113/335 (33%)

Query: 631  PPAQGKKGLKMPVPGNPAVPGMP-------NAGLPGV----------GLPSA-------G 666
            P   G KG+  P PGNP +PG P       + G PG           G+P         G
Sbjct: 1127 PGPPGPKGISGP-PGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG 1185

Query: 667  LPGAGLPST-GLPGSAITSA--GLPGA-GMPSAGIPSAGGEE--HAFLTV-------GSK 713
             PG G P   GLPG +      GLPG  G P  G+P   GE   H F  V       GS 
Sbjct: 1186 QPGFGNPGPPGLPGLSGQKGDGGLPGIPGNP--GLPGPKGEPGFHGFPGVQGPPGPPGSP 1243

Query: 714  -------EANNGP--PFNFPGNFGGSNAFGPPIPP--PGLGG--GAFGD-ARPGMPSV-- 757
                   + N GP  P   PG  G     GP  PP  PG GG  G  G+  +PG+P +  
Sbjct: 1244 GPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG 1303

Query: 758  -----------GNSGLPGL-------GLD-VPGFGG--GPNNLSGPSGFGGGPQNFGN-G 795
                       GN G PGL       GL  VPGF G  GP+ + G +G  G P   G  G
Sbjct: 1304 LKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPG 1363

Query: 796  PGSLGGPPGFG------SGPPGLGSAPGHLGGPPAFGPGPGPGPG--------------- 834
            P  L GP G        +GPPG+   PG  G P   GP   PGP                
Sbjct: 1364 PPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD 1423

Query: 835  --------------PGPIHIGGPPGFASSSGKPGP 855
                          PG   + GPPG     G PGP
Sbjct: 1424 GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGP 1458



 Score = 81.3 bits (199), Expect = 4e-15
 Identities = 79/220 (35%), Positives = 88/220 (40%), Gaps = 42/220 (19%)

Query: 645  GNPAVPGMPNAGLPGVGLPSA--GLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGG 702
            G    PG+P  G+PGV  P    GLPG      G PG +    GLPG   P  G P   G
Sbjct: 964  GEKGEPGLP--GIPGVSGPKGYQGLPG----DPGQPGLS-GQPGLPGPPGPK-GNPGLPG 1015

Query: 703  EEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPP-----PGLGGGAFGDARPGMPSV 757
            +       G K         FPG  G     GP   P     PGL G       PG+ S+
Sbjct: 1016 QPGLIGPPGLKGTIGD--MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI 1073

Query: 758  GNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPG 817
            G  GLPG           P    G  G+ G P       GS+G P     G PGL   PG
Sbjct: 1074 GLPGLPG-----------PKGEPGLPGYPGNP----GIKGSVGDP-----GLPGLPGTPG 1113

Query: 818  HLGGP--PAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGP 855
              G P  P F   PGP   PGP  I GPPG     G+PGP
Sbjct: 1114 AKGQPGLPGFPGTPGP---PGPKGISGPPGNPGLPGEPGP 1150



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 83/236 (35%), Positives = 91/236 (38%), Gaps = 60/236 (25%)

Query: 644 PGNPAVPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSA--GLPGA-GMPSA-GIPS 699
           PG P +PG+P  G PG    S G PG      G  G A  +   GLPG  G P A G P 
Sbjct: 493 PGQPGLPGLP--GPPG----SLGFPG----QKGEKGQAGATGPKGLPGIPGAPGAPGFPG 542

Query: 700 AGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPP--PGLGGGAFGDARPGMPSV 757
           + GE    LT             FPG  G     G P  P  PGL G    D  PG+P  
Sbjct: 543 SKGEPGDILT-------------FPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLP-- 587

Query: 758 GNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGS-GPPGLGSAP 816
           G  G PG G+   G  G P N     G  G P N G       GPPGFG  GP G     
Sbjct: 588 GPKGEPG-GITFKGERGPPGN----PGLPGLPGNIGPM-----GPPGFGPPGPVGEKGIQ 637

Query: 817 GHLGGPPAFG-PGPGPGPGP-----------------GPIHIGGPPGFASSSGKPG 854
           G  G P   G PGP   PG                  G + + G PG     G PG
Sbjct: 638 GVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG 693



 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 95/310 (30%), Positives = 115/310 (37%), Gaps = 60/310 (19%)

Query: 631 PPAQGKKGLKMP--VPGNPAVPGMPNAGLPGV-GLPSA-GLPGAG--LPSTGLPGSAITS 684
           P   G KG++ P  +PG P  PG+P  G+PG  G P   G+PG        G PGS    
Sbjct: 83  PGPPGPKGIRGPPGLPGFPGTPGLP--GMPGHDGAPGPQGIPGCNGTKGERGFPGSP--- 137

Query: 685 AGLPGAGMPSA--GIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGP-----PI 737
            G PG   P    GIP   GE  + + + S     G P  +PG  G     GP     PI
Sbjct: 138 -GFPGLQGPPGPPGIPGMKGEPGSII-MSSLPGPKGNP-GYPGPPGIQGLPGPTGIPGPI 194

Query: 738 PPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSG------------- 784
            PPG  G       PG+P  G  G  GL    P    G   L GP G             
Sbjct: 195 GPPGPPGLMGPPGPPGLP--GPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252

Query: 785 --FGGGPQNFGNGPGSLG--------GPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPG-- 832
             F  G Q      G  G        GPPG   G  G    PG  G P   G    PG  
Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 833 -----PG-PGPIHIGGPPGFASSSGKPGPTVIKVQNMPFTVSIDEILDFFYGYQVIPGSV 886
                PG PG     G  G    +G PGP  + +      ++I E  +   G   +PG  
Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNI--GLPGLPG-- 368

Query: 887 CLKYNEKGMP 896
             +  E+G P
Sbjct: 369 --EKGERGFP 376



 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 95/286 (33%), Positives = 107/286 (37%), Gaps = 71/286 (24%)

Query: 631 PPAQGKKGLKMP----VPGNPAVPGMP-------NAGLPGVGLPSA----GLPGA-GLPS 674
           P  QG  GL  P    V G P  PG P       + G PG+ +P      G PGA GLP 
Sbjct: 376 PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLP- 434

Query: 675 TGLPGSA---------ITSAGLPGA-GMPS-------AGIPSAGGEEHAFLTVGSKEANN 717
            G PG A         I   G PG  G P         G+    G+   F  +G+  +  
Sbjct: 435 -GPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT-CFNCIGTGISGP 492

Query: 718 ----------GPP--FNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGL 765
                     GPP    FPG  G     G    P GL G       PG P  G+ G PG 
Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGAT-GPKGLPGIPGAPGAPGFP--GSKGEPGD 549

Query: 766 GLDVPGFGGGPNNLSGPS-----GFGGGPQNFG--NGPGSLGGPPGFG-------SGPPG 811
            L  PG  G    L  P      G  G P   G    PG  G P G          G PG
Sbjct: 550 ILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609

Query: 812 LGSAPGHLG--GPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGP 855
           L   PG++G  GPP FGP PGP    G   + G PG     G PGP
Sbjct: 610 LPGLPGNIGPMGPPGFGP-PGPVGEKGIQGVAGNPG---QPGIPGP 651



 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 81/224 (36%), Positives = 88/224 (39%), Gaps = 42/224 (18%)

Query: 657 LPGVGLPSAGLPGAGLPSTGLPGSAITSAGL-PGAGMPSAGIPSAGGEEHAFLTVGSKEA 715
           L GV L +AGL    L   G P  A    G  PG+    +GI    GE          E 
Sbjct: 3   LRGVSL-AAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERG----FPGLEG 57

Query: 716 NNGPPFNFPGNFGGSNAFGPP----IP-PPGLGGGAFGDARPGMPSVGNSGLPGLGLDVP 770
           + G P  FPG  G     G      IP PPG  G       PG P  G  GLPG+    P
Sbjct: 58  HPGLP-GFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP--GTPGLPGM----P 110

Query: 771 GFGGGPNNLSGPSGFGG-----GPQNFGNGPGSLG-----GPPGFGS--GPPG---LGSA 815
           G  G P    GP G  G     G + F   PG  G     GPPG     G PG   + S 
Sbjct: 111 GHDGAP----GPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSL 166

Query: 816 PGHLG-----GPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPG 854
           PG  G     GPP     PGP   PGPI   GPPG     G PG
Sbjct: 167 PGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 84/235 (35%), Positives = 94/235 (40%), Gaps = 60/235 (25%)

Query: 628  EKNPPAQGKKGLKMPVPGNPAVPGMPNAGLPGV----GLP----SAGLPGAG--LPSTGL 677
            E  P   G  G+K    GNP  PG+P  GLPG+    G P    + G PG        GL
Sbjct: 1275 EGPPGLPGNGGIKGE-KGNPGQPGLP--GLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGL 1331

Query: 678  PGSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPI 737
            PG      G PG   PS G+P + G E     +G      GPP   PG  G S       
Sbjct: 1332 PGVP----GFPGMKGPS-GVPGSAGPEGEPGLIGPP----GPP-GLPGPSGQSIIIKGDA 1381

Query: 738  PPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPG 797
             PPG+         PG P  G  GLPG          GP  L GP+G  G P     G  
Sbjct: 1382 GPPGI---------PGQP--GLKGLPG--------PQGPQGLPGPTGPPGDP-----GRN 1417

Query: 798  SLGGPPGFGS--GPPGLGSAPGHLG--GPPAFGPGPGPGPGPGPIHIGGPPGFAS 848
             L G  G G   G PGL   PG  G  GPP  GP    GP        GPPG +S
Sbjct: 1418 GLPGFDGAGGRKGDPGLPGQPGTRGLDGPP--GPDGLQGP-------PGPPGTSS 1463



 Score = 67.4 bits (163), Expect = 6e-11
 Identities = 85/259 (32%), Positives = 96/259 (37%), Gaps = 61/259 (23%)

Query: 626 EIEKNPPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSAGLPGA----GLPSTGLPGSA 681
           ++E     QG  G + P PG P + G P  G PG      G  G     G P        
Sbjct: 252 DVEFQKGDQGLPGDRGP-PGPPGIRGPP--GPPGGEKGEKGEQGEPGKRGKPGKDGENGQ 308

Query: 682 ITSAGLPG-AGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPP---I 737
               GLPG  G P  G P   GE+        ++ + GPP             GPP   I
Sbjct: 309 PGIPGLPGDPGYP--GEPGRDGEK-------GQKGDTGPP-------------GPPGLVI 346

Query: 738 PPPGLG---GGAFGDARPGMPSV-GNSGLPGLGLDVPGFGGGPNNLSGPSGFG----GGP 789
           P PG G   G       PG+P   G  G PG+         GP  L GP G       GP
Sbjct: 347 PRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQ--------GPPGLPGPPGAAVMGPPGP 398

Query: 790 QNFGNGPGSLG--GPPGFG-SGPPGLGSAPGHLGGPPAFGP-GPGPGPG-----PGPIHI 840
             F    G  G  GPPG    GPPGL   PG  G P   GP GP   P      PGP   
Sbjct: 399 PGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP--- 455

Query: 841 GGPPGFASSSGKPGPTVIK 859
            GPPG     G  G   +K
Sbjct: 456 PGPPGSPGDKGLQGEQGVK 474



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 79/260 (30%), Positives = 94/260 (36%), Gaps = 48/260 (18%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSAGLPG--AGLPSTGLPGSAITSAGLP 688
           P  +G++G    + G P +PG P A + G   P  G PG        G PG +I   G P
Sbjct: 367 PGEKGERGFP-GIQGPPGLPGPPGAAVMGPPGPP-GFPGERGQKGDEGPPGISIP--GPP 422

Query: 689 GA-GMPSA-GIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPP--PGLGG 744
           G  G P A G+P   G     +    +    GPP             GPP  P   GL G
Sbjct: 423 GLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPP-------------GPPGSPGDKGLQG 469

Query: 745 -----GAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSL 799
                G  GD        G SG PG    +PG  G P +L  P   G   Q    GP  L
Sbjct: 470 EQGVKGDKGDTCFNCIGTGISGPPGQP-GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGL 528

Query: 800 GGPPGFGSGP---------------PGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPP 844
            G PG    P               PG+    G LG P A    PG    PG     G P
Sbjct: 529 PGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGA----PGLPGLPGTPGQDGLP 584

Query: 845 GFASSSGKPGPTVIKVQNMP 864
           G     G+PG    K +  P
Sbjct: 585 GLPGPKGEPGGITFKGERGP 604



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 85/266 (31%), Positives = 98/266 (36%), Gaps = 56/266 (21%)

Query: 634 QGKKGLKMPVPGNPAVPGMPNA-GLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPG-AG 691
           +G++G    + G+P +PG P   G PG   P       G+P    P       GLPG  G
Sbjct: 47  KGERGFP-GLEGHPGLPGFPGPEGPPG---PRGQKGDDGIPGPPGPKGIRGPPGLPGFPG 102

Query: 692 MPSAGIPSAGGEEHAFLTVGSKEANNGP-PFNFPGNFGGSNAFGPPIPP--PGLGG---- 744
            P  G+P   G + A    G    N       FPG+ G     GPP PP  PG+ G    
Sbjct: 103 TP--GLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGS 160

Query: 745 -------GAFGDARPGMPSV-GNSGLPG-LGLDVPGFGGGPNNLSGPSGFGGGPQNFGN- 794
                  G  G+  PG P   G  GLPG  G+  P    GP  L GP G  G P   GN 
Sbjct: 161 IIMSSLPGPKGN--PGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNM 218

Query: 795 -----------GPGSLGGPPG---------------FGSGPPGLGSAPGHLGGPPAFGPG 828
                      G   L GPPG               F  G  GL    G  G P   GP 
Sbjct: 219 GLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP- 277

Query: 829 PGPGPGPGPIHIGGPPGFASSSGKPG 854
             PGP  G     G  G     GKPG
Sbjct: 278 --PGPPGGEKGEKGEQGEPGKRGKPG 301



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 35/128 (27%), Positives = 42/128 (32%), Gaps = 20/128 (15%)

Query: 160  PNMGASFGSPTFSSTVPSTA--SPMNTVPPPPIPPIPAMPSLPPMPS------------- 204
            P      G P    T+       P     PP    +P  P  P +P              
Sbjct: 1014 PGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI 1073

Query: 205  -IPPIPVPPPVPTLPPVPPVPPIPPV---PSVPPMTPLPPMSGMPPLNPPPVAPLPAGMN 260
             +P +P P   P LP  P  P I      P +P +   P   G P L   P  P P G  
Sbjct: 1074 GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK 1133

Query: 261  G-SGAPMN 267
            G SG P N
Sbjct: 1134 GISGPPGN 1141



 Score = 38.9 bits (89), Expect = 0.023
 Identities = 38/148 (25%), Positives = 47/148 (31%), Gaps = 47/148 (31%)

Query: 175 VPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTL----------------- 217
           +P    P     PP +P  P  P LP MP     P P  +P                   
Sbjct: 82  IPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141

Query: 218 ---PPVPPVPP-------------------IPPVPSVPPMTPLPPMSGMP-PLNPPPVAP 254
              PP PP  P                    P  P  P +  LP  +G+P P+ PP    
Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPG--- 198

Query: 255 LPAGMNGSGAPMNL---NNNLNPMFLGP 279
            P G+ G   P  L     N+   F GP
Sbjct: 199 -PPGLMGPPGPPGLPGPKGNMGLNFQGP 225



 Score = 38.9 bits (89), Expect = 0.023
 Identities = 37/145 (25%), Positives = 49/145 (33%), Gaps = 14/145 (9%)

Query: 160 PNMGASFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVP---T 216
           P    S G P    T P        +  P  P +P +P  P    +P +P P   P   T
Sbjct: 538 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT 597

Query: 217 LPPVPPVPPIPPVPSVPPMTPLPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMF 276
                  P  P +P +P          + P+ PP   P P  +   G      N   P  
Sbjct: 598 FKGERGPPGNPGLPGLP--------GNIGPMGPPGFGP-PGPVGEKGIQGVAGNPGQPGI 648

Query: 277 LGPLNPVNPIQMNSQSSVKPLPINP 301
            GP    +P Q  +Q     LP NP
Sbjct: 649 PGPKG--DPGQTITQPGKPGLPGNP 671



 Score = 38.9 bits (89), Expect = 0.023
 Identities = 39/151 (25%), Positives = 51/151 (33%), Gaps = 31/151 (20%)

Query: 159 PPNMGASFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLP 218
           PP +    G P     +P         P PP   +P  P     P IP  P P   P  P
Sbjct: 826 PPGIPGPIGQPGLHG-IPGEKGD----PGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSP 880

Query: 219 PVPPV-----------------PPIPPVP-SVPPMTPLPPMSGMPPLNPPPVAPLPAGMN 260
            +P                   PP PP P  +P  + +P + G   L   P  P P G  
Sbjct: 881 GLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEK 940

Query: 261 GSGAPMNLNNNLNPMFLGPLNPVNPIQMNSQ 291
           GS           P   GP  P++P  + S+
Sbjct: 941 GSKG--------EPGLPGPPGPMDPNLLGSK 963



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 28/99 (28%), Positives = 36/99 (36%), Gaps = 1/99 (1%)

Query: 167 GSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPI 226
           G+P           P  T+  P  P +P  P       +P  P  P  P LP +P     
Sbjct: 641 GNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGE 700

Query: 227 PPVPSVPPMTPLPPMSGMPPLNPPPVAPLPAGMNGSGAP 265
           P +P +    P P   G P +  PP AP   G  G   P
Sbjct: 701 PGIPGIGLPGP-PGPKGFPGIPGPPGAPGTPGRIGLEGP 738



 Score = 37.0 bits (84), Expect = 0.086
 Identities = 44/176 (25%), Positives = 55/176 (31%), Gaps = 30/176 (17%)

Query: 98   PPANASRSGPPPSSGMSSRVNLPTTVSNFNNPSPSVVTATTSVHESNKNIQTFSTASVGT 157
            PP      G P   G+     L  T+ +   P P  V                       
Sbjct: 1004 PPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPG------------------ 1045

Query: 158  APPNMGASFGSPTFSSTVPSTASP-MNTVPPPPIPPIPAMPSLPPMPSIPPI------PV 210
             P  +    GSP           P ++++  P +P     P LP  P  P I      P 
Sbjct: 1046 -PSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPG 1104

Query: 211  PPPVPTLPPVPPVPPIPPVPSVPPMTPLPPMSGMPPLNPP-PVAPLPAGMNGSGAP 265
             P +P  P     P +P  P  P   P P     PP NP  P  P P G  G G P
Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPG-PPGPKGISGPPGNPGLPGEPGPVG--GGGHP 1157



 Score = 35.8 bits (81), Expect = 0.19
 Identities = 43/146 (29%), Positives = 52/146 (35%), Gaps = 25/146 (17%)

Query: 188 PPIPPIPAMPSLPPMPSIPPIPVPPPVPTLP-----PVPPVPPIPPVPSVPPMTPLPPMS 242
           P IP I  +P  P     P IP PP  P  P       PP PP  P P   P   LP   
Sbjct: 701 PGIPGI-GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPP 759

Query: 243 GMP-------PLNP--------PPVAPLPAGMNGSGAPM-NLNNNLNPMFLGPLNPVNPI 286
           G P        L P        PP  P   G++G   P  ++  N  P   GP+ P    
Sbjct: 760 GPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQP---GPMGPPGLP 816

Query: 287 QMNSQSSVKPLPINPDDLYVSVHGMP 312
            +  Q    P  I        +HG+P
Sbjct: 817 GIGVQGPPGPPGIPGPIGQPGLHGIP 842



 Score = 35.0 bits (79), Expect = 0.33
 Identities = 28/80 (35%), Positives = 32/80 (40%), Gaps = 5/80 (6%)

Query: 159 PPNMGASFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLP 218
           PP  GA+   P      P          PP I  IP  P L   P  P +P  PP P  P
Sbjct: 387 PP--GAAVMGPPGPPGFPGERGQKGDEGPPGIS-IPGPPGLDGQPGAPGLP-GPPGPAGP 442

Query: 219 PVPPVPPI-PPVPSVPPMTP 237
            +PP   I  P P  PP +P
Sbjct: 443 HIPPSDEICEPGPPGPPGSP 462



 Score = 35.0 bits (79), Expect = 0.33
 Identities = 26/82 (31%), Positives = 30/82 (36%), Gaps = 4/82 (4%)

Query: 187  PPPIPPIPAMPS---LPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLPPMSG 243
            PP +P +        LP +P  P +P P   P     P V   PP P   P   L    G
Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQG-PPGPPGSPGPALEGPKG 1252

Query: 244  MPPLNPPPVAPLPAGMNGSGAP 265
             P    PP  P P G  G   P
Sbjct: 1253 NPGPQGPPGRPGPTGFQGLPGP 1274



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 30/101 (29%), Positives = 37/101 (36%), Gaps = 21/101 (20%)

Query: 186  PPPPIPPIPAMPSL---------PPMPSIPPIPVPPPVPTLPPVPPVPPI---PPVPSVP 233
            P  P PP P  P+L         P +P IP +  P     LP  P  P +   P +P  P
Sbjct: 946  PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005

Query: 234  PMTPLPPMSGMPPLNPPPVA---------PLPAGMNGSGAP 265
                 P + G P L  PP           P P G+ G   P
Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGP 1046



 Score = 31.2 bits (69), Expect = 4.7
 Identities = 23/89 (25%), Positives = 33/89 (37%), Gaps = 17/89 (19%)

Query: 194  PAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLPPMSGMPPLNPPPVA 253
            P  P LP +P +     PP +   P  P +  +   P +P +   P M G          
Sbjct: 1293 PGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKG---------- 1342

Query: 254  PLPAGMNGSGAPMNLNNNLNPMFLGPLNP 282
              P+G+ GS  P        P  +GP  P
Sbjct: 1343 --PSGVPGSAGPEG-----EPGLIGPPGP 1364


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
           sapiens]
          Length = 1685

 Score =  101 bits (251), Expect = 4e-21
 Identities = 97/247 (39%), Positives = 110/247 (44%), Gaps = 49/247 (19%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMP----NAGLPGVGLPSAGLPGA-GLPSTGLPGSAITSA 685
           P  +G  G  +  PG P +PG P    + GLPG      GLPG  GLP  G+PGS     
Sbjct: 649 PGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPG----DPGLPGQPGLP--GIPGSK-GEP 701

Query: 686 GLPGAGMPSA----GIPSAGGEEHAFLTVG--SKEANNGPPFNFPGNFG--GSNAFGPPI 737
           G+PG G+P      G P   G   A  T G    E   GPP  FPG  G  G    GPP 
Sbjct: 702 GIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPP-GFPGPKGEPGFALPGPPG 760

Query: 738 PP--PGLGG--GAFGDAR-PGMPSV-GNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQN 791
           PP  PG  G  G  GD   PG P   G +GL GL         GP    GP+G       
Sbjct: 761 PPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP--------GPKGDVGPNG------- 805

Query: 792 FGNGPGSLGGP--PGFG-SGPPGLGSAPGHLGGPPAFG-PGPGPGPGPGPIHIGGPPGFA 847
               PG +G P  PG G  GPPG    PG +G P   G PG    PGP  + + GPPG  
Sbjct: 806 ---QPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGER 862

Query: 848 SSSGKPG 854
            S G PG
Sbjct: 863 GSPGIPG 869



 Score = 88.2 bits (217), Expect = 3e-17
 Identities = 100/278 (35%), Positives = 111/278 (39%), Gaps = 60/278 (21%)

Query: 631  PPAQGKKGLKMP--VPGNPAVPGMP-------NAGLPGVGLPSAGLPGA----GLPS-TG 676
            P  QG +G   P  VPG P  PG+P       + G+  +GLP  GLPG     GLP   G
Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLP--GLPGPKGEPGLPGYPG 1092

Query: 677  LPG--SAITSAGLPGA-GMPSA-GIPSAGGEEHAFLTVGSKEANNGPPFN-----FPGNF 727
             PG   ++   GLPG  G P A G P   G        G K  + GPP N      PG  
Sbjct: 1093 NPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS-GPPGNPGLPGEPGPV 1151

Query: 728  GGSNAFGPPIPP--------PGLGGGAFGDARPGMPSVGNSGLPGL-GLD-------VPG 771
            GG    G P PP         G+ G A     PG P  GN G PGL GL        +PG
Sbjct: 1152 GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPG 1211

Query: 772  FGGGPNNLSGPSG---FGGGPQNFGNGPGSLGGPPGFG----SGPPGLGSAPGHLGGPPA 824
              G P  L GP G   F G P     GP    G PG       G PG    PG  G P  
Sbjct: 1212 IPGNPG-LPGPKGEPGFHGFPGV--QGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGP 1268

Query: 825  FGPGPGPGPG--------PGPIHIGGPPGFASSSGKPG 854
             GP   PG G        PG   + G PG     G PG
Sbjct: 1269 EGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPG 1306



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 99/293 (33%), Positives = 115/293 (39%), Gaps = 79/293 (26%)

Query: 631  PPAQGKKGLK-MPVPGNPAVPGMPNA-GLPGV-GLPSA-GLPGA-GLPSTGLPGSAITSA 685
            P   G  GL  + V G P  PG+P   G PG+ G+P   G PG  GL   G PG    S 
Sbjct: 807  PGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGER-GSP 865

Query: 686  GLPGAGMP-----SAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPP- 739
            G+PGA  P     S G+P   G                    FPG  G     GPP PP 
Sbjct: 866  GIPGAPGPIGPPGSPGLPGKAGAS-----------------GFPGTKGEMGMMGPPGPPG 908

Query: 740  ----------PGLGGGAFGDARPGMP-------SVGNSGLPG---------LGLD----V 769
                      PGL G      +PG+P       S G  GLPG         LG       
Sbjct: 909  PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGE 968

Query: 770  PGFGGGPNNLSGPSGFGGGPQNFG----NGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAF 825
            PG  G P  +SGP G+ G P + G    +G   L GPPG   G PGL   PG +G P   
Sbjct: 969  PGLPGIPG-VSGPKGYQGLPGDPGQPGLSGQPGLPGPPG-PKGNPGLPGQPGLIGPPGLK 1026

Query: 826  G-------PGPG-----PGPGPGPIHIGGP--PGFASSSGKPGPTVIKVQNMP 864
            G       PGP      PGP   P   G P  PG     G PG + I +  +P
Sbjct: 1027 GTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLP 1079



 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 96/298 (32%), Positives = 114/298 (38%), Gaps = 93/298 (31%)

Query: 631  PPAQGKKGLK-MPVPGNPAVPGMP-------NAGLPGV----GLPSA-------GLPGAG 671
            P   G+KG    P  GNP  PG+P       + GLPG+    GLP         G PG  
Sbjct: 1175 PGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQ 1234

Query: 672  LPS--TGLPGSAITSA-------------GLPGAGMPSAGIPSAGGEEHAFLTVGSKEAN 716
             P    G PG A+                GLPG   P  G+P  GG       +  ++ N
Sbjct: 1235 GPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPP-GLPGNGG-------IKGEKGN 1286

Query: 717  NGPPFNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMPSV-GNSGLPGLGLDVPGFGG- 774
             G P   PG  G     GPP    GL G      RPG+  + G+ GLPG    VPGF G 
Sbjct: 1287 PGQP-GLPGLPGLKGDQGPP----GLQGNP---GRPGLNGMKGDPGLPG----VPGFPGM 1334

Query: 775  -GPNNLSGPSGFGGGPQNFGN-GPGSLGGPPGFG------SGPPGLGSAPGHLGGPPAFG 826
             GP+ + G +G  G P   G  GP  L GP G        +GPPG+   PG  G P   G
Sbjct: 1335 KGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQG 1394

Query: 827  PGPGPGPG-----------------------------PGPIHIGGPPGFASSSGKPGP 855
            P   PGP                              PG   + GPPG     G PGP
Sbjct: 1395 PQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGP 1452



 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 95/274 (34%), Positives = 110/274 (40%), Gaps = 66/274 (24%)

Query: 631  PPAQGKKGLKMPV--PGNPAVPGMPNA-GLPGVG--LPSAGLPGA----GLPS-TGLPGS 680
            P   G+ GL  P    GNP +PG P   G PG+   +   G PG     G P  +G+PG 
Sbjct: 993  PGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQ 1052

Query: 681  AITSAGLPGA-------GMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAF 733
               S GLPG        G+ S G+P   G +             G P  +PGN G   + 
Sbjct: 1053 P-GSPGLPGQKGDKGDPGISSIGLPGLPGPK----------GEPGLP-GYPGNPGIKGSV 1100

Query: 734  GPPIPPPGLGGGAFGDARPGMPSV----------------GNSGLPGLGLDVPGFGGGPN 777
            G P   PGL G      +PG+P                  GN GLPG     P  GGG  
Sbjct: 1101 GDP-GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGE--PGPVGGGGHP 1157

Query: 778  NLSGPSGFGGGPQNFGNGPGSLG-----GPPGFGS-GPPGLGSAPGHLG--GPPAFGPGP 829
               GP G  G P   G  PG  G     G PGFG+ GPPGL    G  G  G P     P
Sbjct: 1158 GQPGPPGEKGKPGQDGI-PGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNP 1216

Query: 830  G-PGPGPGPIHIG-----GPPGFASSSGKPGPTV 857
            G PGP   P   G     GPPG     G PGP +
Sbjct: 1217 GLPGPKGEPGFHGFPGVQGPPG---PPGSPGPAL 1247



 Score = 81.3 bits (199), Expect = 4e-15
 Identities = 79/220 (35%), Positives = 88/220 (40%), Gaps = 42/220 (19%)

Query: 645  GNPAVPGMPNAGLPGVGLPSA--GLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGG 702
            G    PG+P  G+PGV  P    GLPG      G PG +    GLPG   P  G P   G
Sbjct: 964  GEKGEPGLP--GIPGVSGPKGYQGLPG----DPGQPGLS-GQPGLPGPPGPK-GNPGLPG 1015

Query: 703  EEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPP-----PGLGGGAFGDARPGMPSV 757
            +       G K         FPG  G     GP   P     PGL G       PG+ S+
Sbjct: 1016 QPGLIGPPGLKGTIGD--MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI 1073

Query: 758  GNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPG 817
            G  GLPG           P    G  G+ G P       GS+G P     G PGL   PG
Sbjct: 1074 GLPGLPG-----------PKGEPGLPGYPGNP----GIKGSVGDP-----GLPGLPGTPG 1113

Query: 818  HLGGP--PAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGP 855
              G P  P F   PGP   PGP  I GPPG     G+PGP
Sbjct: 1114 AKGQPGLPGFPGTPGP---PGPKGISGPPGNPGLPGEPGP 1150



 Score = 80.9 bits (198), Expect = 5e-15
 Identities = 87/254 (34%), Positives = 99/254 (38%), Gaps = 36/254 (14%)

Query: 631  PPAQGKKGLKMPVPGNPAVPGMPNA-GLPGVGLPSA--GLPGAG--LPSTGLPGSAITSA 685
            P   G KG +  +PG+P  PG+    GLPG   P    GLPG    +   GL G+ I   
Sbjct: 975  PGVSGPKGYQ-GLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT-IGDM 1032

Query: 686  GLPGA----GMPS-AGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPP- 739
            G PG     G P  +G+P   G        G K          PG  G     G P  P 
Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPG 1092

Query: 740  -PGLGGGAFGDARPGMPSV-GNSGLPGLGLDVPGFGG-----GPNNLSGPSG-------- 784
             PG+ G       PG+P   G  G PGL    PGF G     GP  +SGP G        
Sbjct: 1093 NPGIKGSVGDPGLPGLPGTPGAKGQPGL----PGFPGTPGPPGPKGISGPPGNPGLPGEP 1148

Query: 785  --FGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPG-PGPIHIG 841
               GGG      GP    G PG   G PG     G  G P    PGP   PG  G    G
Sbjct: 1149 GPVGGGGHPGQPGPPGEKGKPG-QDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDG 1207

Query: 842  GPPGFASSSGKPGP 855
            G PG   + G PGP
Sbjct: 1208 GLPGIPGNPGLPGP 1221



 Score = 80.9 bits (198), Expect = 5e-15
 Identities = 110/299 (36%), Positives = 119/299 (39%), Gaps = 85/299 (28%)

Query: 631  PPAQGKKGLKMPVPGNPAVPGMP-------NAGLPGV----------GLPSA-------G 666
            P   G KG+  P PGNP +PG P       + G PG           G+P         G
Sbjct: 1127 PGPPGPKGISGP-PGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG 1185

Query: 667  LPGAGLPST-GLPGSAITSA--GLPGA-GMPSAGIPSAGGEE--HAFLTV-------GSK 713
             PG G P   GLPG +      GLPG  G P  G+P   GE   H F  V       GS 
Sbjct: 1186 QPGFGNPGPPGLPGLSGQKGDGGLPGIPGNP--GLPGPKGEPGFHGFPGVQGPPGPPGSP 1243

Query: 714  -EANNGPPFNFPGNFGGSNAFGPPIP--PPGL--GGGAFGD-ARPGMPSVGNSGLPGLGL 767
              A  GP  N PG  G     G P P  PPGL   GG  G+   PG P  G  GLPGL  
Sbjct: 1244 GPALEGPKGN-PGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQP--GLPGLPGLKG 1300

Query: 768  DV--PGFGGGP-----NNLSGPSGFGGGPQNFG-----NGPGSLG--GPPGFGSGPPGLG 813
            D   PG  G P     N + G  G  G P   G       PGS G  G PG   GPPG  
Sbjct: 1301 DQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGL-IGPPGPP 1359

Query: 814  SAPGHLG---------GPPAFGPGPG----PGPG-----PGPIHIGGPPGFASSSGKPG 854
              PG  G         GPP     PG    PGP      PGP    GPPG    +G PG
Sbjct: 1360 GLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPT---GPPGDPGRNGLPG 1415



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 83/236 (35%), Positives = 91/236 (38%), Gaps = 60/236 (25%)

Query: 644 PGNPAVPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSA--GLPGA-GMPSA-GIPS 699
           PG P +PG+P  G PG    S G PG      G  G A  +   GLPG  G P A G P 
Sbjct: 493 PGQPGLPGLP--GPPG----SLGFPG----QKGEKGQAGATGPKGLPGIPGAPGAPGFPG 542

Query: 700 AGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPP--PGLGGGAFGDARPGMPSV 757
           + GE    LT             FPG  G     G P  P  PGL G    D  PG+P  
Sbjct: 543 SKGEPGDILT-------------FPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLP-- 587

Query: 758 GNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGS-GPPGLGSAP 816
           G  G PG G+   G  G P N     G  G P N G       GPPGFG  GP G     
Sbjct: 588 GPKGEPG-GITFKGERGPPGN----PGLPGLPGNIGPM-----GPPGFGPPGPVGEKGIQ 637

Query: 817 GHLGGPPAFG-PGPGPGPGP-----------------GPIHIGGPPGFASSSGKPG 854
           G  G P   G PGP   PG                  G + + G PG     G PG
Sbjct: 638 GVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG 693



 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 95/310 (30%), Positives = 115/310 (37%), Gaps = 60/310 (19%)

Query: 631 PPAQGKKGLKMP--VPGNPAVPGMPNAGLPGV-GLPSA-GLPGAG--LPSTGLPGSAITS 684
           P   G KG++ P  +PG P  PG+P  G+PG  G P   G+PG        G PGS    
Sbjct: 83  PGPPGPKGIRGPPGLPGFPGTPGLP--GMPGHDGAPGPQGIPGCNGTKGERGFPGSP--- 137

Query: 685 AGLPGAGMPSA--GIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGP-----PI 737
            G PG   P    GIP   GE  + + + S     G P  +PG  G     GP     PI
Sbjct: 138 -GFPGLQGPPGPPGIPGMKGEPGSII-MSSLPGPKGNP-GYPGPPGIQGLPGPTGIPGPI 194

Query: 738 PPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSG------------- 784
            PPG  G       PG+P  G  G  GL    P    G   L GP G             
Sbjct: 195 GPPGPPGLMGPPGPPGLP--GPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252

Query: 785 --FGGGPQNFGNGPGSLG--------GPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPG-- 832
             F  G Q      G  G        GPPG   G  G    PG  G P   G    PG  
Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 833 -----PG-PGPIHIGGPPGFASSSGKPGPTVIKVQNMPFTVSIDEILDFFYGYQVIPGSV 886
                PG PG     G  G    +G PGP  + +      ++I E  +   G   +PG  
Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNI--GLPGLPG-- 368

Query: 887 CLKYNEKGMP 896
             +  E+G P
Sbjct: 369 --EKGERGFP 376



 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 95/286 (33%), Positives = 107/286 (37%), Gaps = 71/286 (24%)

Query: 631 PPAQGKKGLKMP----VPGNPAVPGMP-------NAGLPGVGLPSA----GLPGA-GLPS 674
           P  QG  GL  P    V G P  PG P       + G PG+ +P      G PGA GLP 
Sbjct: 376 PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLP- 434

Query: 675 TGLPGSA---------ITSAGLPGA-GMPS-------AGIPSAGGEEHAFLTVGSKEANN 717
            G PG A         I   G PG  G P         G+    G+   F  +G+  +  
Sbjct: 435 -GPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT-CFNCIGTGISGP 492

Query: 718 ----------GPP--FNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGL 765
                     GPP    FPG  G     G    P GL G       PG P  G+ G PG 
Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGAT-GPKGLPGIPGAPGAPGFP--GSKGEPGD 549

Query: 766 GLDVPGFGGGPNNLSGPS-----GFGGGPQNFG--NGPGSLGGPPGFG-------SGPPG 811
            L  PG  G    L  P      G  G P   G    PG  G P G          G PG
Sbjct: 550 ILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609

Query: 812 LGSAPGHLG--GPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGP 855
           L   PG++G  GPP FGP PGP    G   + G PG     G PGP
Sbjct: 610 LPGLPGNIGPMGPPGFGP-PGPVGEKGIQGVAGNPG---QPGIPGP 651



 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 81/224 (36%), Positives = 88/224 (39%), Gaps = 42/224 (18%)

Query: 657 LPGVGLPSAGLPGAGLPSTGLPGSAITSAGL-PGAGMPSAGIPSAGGEEHAFLTVGSKEA 715
           L GV L +AGL    L   G P  A    G  PG+    +GI    GE          E 
Sbjct: 3   LRGVSL-AAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERG----FPGLEG 57

Query: 716 NNGPPFNFPGNFGGSNAFGPP----IP-PPGLGGGAFGDARPGMPSVGNSGLPGLGLDVP 770
           + G P  FPG  G     G      IP PPG  G       PG P  G  GLPG+    P
Sbjct: 58  HPGLP-GFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP--GTPGLPGM----P 110

Query: 771 GFGGGPNNLSGPSGFGG-----GPQNFGNGPGSLG-----GPPGFGS--GPPG---LGSA 815
           G  G P    GP G  G     G + F   PG  G     GPPG     G PG   + S 
Sbjct: 111 GHDGAP----GPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSL 166

Query: 816 PGHLG-----GPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPG 854
           PG  G     GPP     PGP   PGPI   GPPG     G PG
Sbjct: 167 PGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 84/235 (35%), Positives = 94/235 (40%), Gaps = 60/235 (25%)

Query: 628  EKNPPAQGKKGLKMPVPGNPAVPGMPNAGLPGV----GLP----SAGLPGAG--LPSTGL 677
            E  P   G  G+K    GNP  PG+P  GLPG+    G P    + G PG        GL
Sbjct: 1269 EGPPGLPGNGGIKGE-KGNPGQPGLP--GLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGL 1325

Query: 678  PGSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPI 737
            PG      G PG   PS G+P + G E     +G      GPP   PG  G S       
Sbjct: 1326 PGVP----GFPGMKGPS-GVPGSAGPEGEPGLIGPP----GPP-GLPGPSGQSIIIKGDA 1375

Query: 738  PPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPG 797
             PPG+         PG P  G  GLPG          GP  L GP+G  G P     G  
Sbjct: 1376 GPPGI---------PGQP--GLKGLPG--------PQGPQGLPGPTGPPGDP-----GRN 1411

Query: 798  SLGGPPGFGS--GPPGLGSAPGHLG--GPPAFGPGPGPGPGPGPIHIGGPPGFAS 848
             L G  G G   G PGL   PG  G  GPP  GP    GP        GPPG +S
Sbjct: 1412 GLPGFDGAGGRKGDPGLPGQPGTRGLDGPP--GPDGLQGP-------PGPPGTSS 1457



 Score = 67.4 bits (163), Expect = 6e-11
 Identities = 85/259 (32%), Positives = 96/259 (37%), Gaps = 61/259 (23%)

Query: 626 EIEKNPPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSAGLPGA----GLPSTGLPGSA 681
           ++E     QG  G + P PG P + G P  G PG      G  G     G P        
Sbjct: 252 DVEFQKGDQGLPGDRGP-PGPPGIRGPP--GPPGGEKGEKGEQGEPGKRGKPGKDGENGQ 308

Query: 682 ITSAGLPG-AGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPP---I 737
               GLPG  G P  G P   GE+        ++ + GPP             GPP   I
Sbjct: 309 PGIPGLPGDPGYP--GEPGRDGEK-------GQKGDTGPP-------------GPPGLVI 346

Query: 738 PPPGLG---GGAFGDARPGMPSV-GNSGLPGLGLDVPGFGGGPNNLSGPSGFG----GGP 789
           P PG G   G       PG+P   G  G PG+         GP  L GP G       GP
Sbjct: 347 PRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQ--------GPPGLPGPPGAAVMGPPGP 398

Query: 790 QNFGNGPGSLG--GPPGFG-SGPPGLGSAPGHLGGPPAFGP-GPGPGPG-----PGPIHI 840
             F    G  G  GPPG    GPPGL   PG  G P   GP GP   P      PGP   
Sbjct: 399 PGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP--- 455

Query: 841 GGPPGFASSSGKPGPTVIK 859
            GPPG     G  G   +K
Sbjct: 456 PGPPGSPGDKGLQGEQGVK 474



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 79/260 (30%), Positives = 94/260 (36%), Gaps = 48/260 (18%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSAGLPG--AGLPSTGLPGSAITSAGLP 688
           P  +G++G    + G P +PG P A + G   P  G PG        G PG +I   G P
Sbjct: 367 PGEKGERGFP-GIQGPPGLPGPPGAAVMGPPGPP-GFPGERGQKGDEGPPGISIP--GPP 422

Query: 689 GA-GMPSA-GIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPP--PGLGG 744
           G  G P A G+P   G     +    +    GPP             GPP  P   GL G
Sbjct: 423 GLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPP-------------GPPGSPGDKGLQG 469

Query: 745 -----GAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSL 799
                G  GD        G SG PG    +PG  G P +L  P   G   Q    GP  L
Sbjct: 470 EQGVKGDKGDTCFNCIGTGISGPPGQP-GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGL 528

Query: 800 GGPPGFGSGP---------------PGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPP 844
            G PG    P               PG+    G LG P A    PG    PG     G P
Sbjct: 529 PGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGA----PGLPGLPGTPGQDGLP 584

Query: 845 GFASSSGKPGPTVIKVQNMP 864
           G     G+PG    K +  P
Sbjct: 585 GLPGPKGEPGGITFKGERGP 604



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 85/266 (31%), Positives = 98/266 (36%), Gaps = 56/266 (21%)

Query: 634 QGKKGLKMPVPGNPAVPGMPNA-GLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPG-AG 691
           +G++G    + G+P +PG P   G PG   P       G+P    P       GLPG  G
Sbjct: 47  KGERGFP-GLEGHPGLPGFPGPEGPPG---PRGQKGDDGIPGPPGPKGIRGPPGLPGFPG 102

Query: 692 MPSAGIPSAGGEEHAFLTVGSKEANNGP-PFNFPGNFGGSNAFGPPIPP--PGLGG---- 744
            P  G+P   G + A    G    N       FPG+ G     GPP PP  PG+ G    
Sbjct: 103 TP--GLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGS 160

Query: 745 -------GAFGDARPGMPSV-GNSGLPG-LGLDVPGFGGGPNNLSGPSGFGGGPQNFGN- 794
                  G  G+  PG P   G  GLPG  G+  P    GP  L GP G  G P   GN 
Sbjct: 161 IIMSSLPGPKGN--PGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNM 218

Query: 795 -----------GPGSLGGPPG---------------FGSGPPGLGSAPGHLGGPPAFGPG 828
                      G   L GPPG               F  G  GL    G  G P   GP 
Sbjct: 219 GLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP- 277

Query: 829 PGPGPGPGPIHIGGPPGFASSSGKPG 854
             PGP  G     G  G     GKPG
Sbjct: 278 --PGPPGGEKGEKGEQGEPGKRGKPG 301



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 35/128 (27%), Positives = 42/128 (32%), Gaps = 20/128 (15%)

Query: 160  PNMGASFGSPTFSSTVPSTA--SPMNTVPPPPIPPIPAMPSLPPMPS------------- 204
            P      G P    T+       P     PP    +P  P  P +P              
Sbjct: 1014 PGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI 1073

Query: 205  -IPPIPVPPPVPTLPPVPPVPPIPPV---PSVPPMTPLPPMSGMPPLNPPPVAPLPAGMN 260
             +P +P P   P LP  P  P I      P +P +   P   G P L   P  P P G  
Sbjct: 1074 GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK 1133

Query: 261  G-SGAPMN 267
            G SG P N
Sbjct: 1134 GISGPPGN 1141



 Score = 38.9 bits (89), Expect = 0.023
 Identities = 38/148 (25%), Positives = 47/148 (31%), Gaps = 47/148 (31%)

Query: 175 VPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTL----------------- 217
           +P    P     PP +P  P  P LP MP     P P  +P                   
Sbjct: 82  IPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141

Query: 218 ---PPVPPVPP-------------------IPPVPSVPPMTPLPPMSGMP-PLNPPPVAP 254
              PP PP  P                    P  P  P +  LP  +G+P P+ PP    
Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPG--- 198

Query: 255 LPAGMNGSGAPMNL---NNNLNPMFLGP 279
            P G+ G   P  L     N+   F GP
Sbjct: 199 -PPGLMGPPGPPGLPGPKGNMGLNFQGP 225



 Score = 38.9 bits (89), Expect = 0.023
 Identities = 37/145 (25%), Positives = 49/145 (33%), Gaps = 14/145 (9%)

Query: 160 PNMGASFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVP---T 216
           P    S G P    T P        +  P  P +P +P  P    +P +P P   P   T
Sbjct: 538 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT 597

Query: 217 LPPVPPVPPIPPVPSVPPMTPLPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMF 276
                  P  P +P +P          + P+ PP   P P  +   G      N   P  
Sbjct: 598 FKGERGPPGNPGLPGLP--------GNIGPMGPPGFGP-PGPVGEKGIQGVAGNPGQPGI 648

Query: 277 LGPLNPVNPIQMNSQSSVKPLPINP 301
            GP    +P Q  +Q     LP NP
Sbjct: 649 PGPKG--DPGQTITQPGKPGLPGNP 671



 Score = 38.9 bits (89), Expect = 0.023
 Identities = 39/151 (25%), Positives = 51/151 (33%), Gaps = 31/151 (20%)

Query: 159 PPNMGASFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLP 218
           PP +    G P     +P         P PP   +P  P     P IP  P P   P  P
Sbjct: 826 PPGIPGPIGQPGLHG-IPGEKGD----PGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSP 880

Query: 219 PVPPV-----------------PPIPPVP-SVPPMTPLPPMSGMPPLNPPPVAPLPAGMN 260
            +P                   PP PP P  +P  + +P + G   L   P  P P G  
Sbjct: 881 GLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEK 940

Query: 261 GSGAPMNLNNNLNPMFLGPLNPVNPIQMNSQ 291
           GS           P   GP  P++P  + S+
Sbjct: 941 GSKG--------EPGLPGPPGPMDPNLLGSK 963



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 28/99 (28%), Positives = 36/99 (36%), Gaps = 1/99 (1%)

Query: 167 GSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPI 226
           G+P           P  T+  P  P +P  P       +P  P  P  P LP +P     
Sbjct: 641 GNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGE 700

Query: 227 PPVPSVPPMTPLPPMSGMPPLNPPPVAPLPAGMNGSGAP 265
           P +P +    P P   G P +  PP AP   G  G   P
Sbjct: 701 PGIPGIGLPGP-PGPKGFPGIPGPPGAPGTPGRIGLEGP 738



 Score = 37.0 bits (84), Expect = 0.086
 Identities = 44/176 (25%), Positives = 55/176 (31%), Gaps = 30/176 (17%)

Query: 98   PPANASRSGPPPSSGMSSRVNLPTTVSNFNNPSPSVVTATTSVHESNKNIQTFSTASVGT 157
            PP      G P   G+     L  T+ +   P P  V                       
Sbjct: 1004 PPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPG------------------ 1045

Query: 158  APPNMGASFGSPTFSSTVPSTASP-MNTVPPPPIPPIPAMPSLPPMPSIPPI------PV 210
             P  +    GSP           P ++++  P +P     P LP  P  P I      P 
Sbjct: 1046 -PSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPG 1104

Query: 211  PPPVPTLPPVPPVPPIPPVPSVPPMTPLPPMSGMPPLNPP-PVAPLPAGMNGSGAP 265
             P +P  P     P +P  P  P   P P     PP NP  P  P P G  G G P
Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPG-PPGPKGISGPPGNPGLPGEPGPVG--GGGHP 1157



 Score = 35.8 bits (81), Expect = 0.19
 Identities = 43/146 (29%), Positives = 52/146 (35%), Gaps = 25/146 (17%)

Query: 188 PPIPPIPAMPSLPPMPSIPPIPVPPPVPTLP-----PVPPVPPIPPVPSVPPMTPLPPMS 242
           P IP I  +P  P     P IP PP  P  P       PP PP  P P   P   LP   
Sbjct: 701 PGIPGI-GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPP 759

Query: 243 GMP-------PLNP--------PPVAPLPAGMNGSGAPM-NLNNNLNPMFLGPLNPVNPI 286
           G P        L P        PP  P   G++G   P  ++  N  P   GP+ P    
Sbjct: 760 GPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQP---GPMGPPGLP 816

Query: 287 QMNSQSSVKPLPINPDDLYVSVHGMP 312
            +  Q    P  I        +HG+P
Sbjct: 817 GIGVQGPPGPPGIPGPIGQPGLHGIP 842



 Score = 35.0 bits (79), Expect = 0.33
 Identities = 28/80 (35%), Positives = 32/80 (40%), Gaps = 5/80 (6%)

Query: 159 PPNMGASFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLP 218
           PP  GA+   P      P          PP I  IP  P L   P  P +P  PP P  P
Sbjct: 387 PP--GAAVMGPPGPPGFPGERGQKGDEGPPGIS-IPGPPGLDGQPGAPGLP-GPPGPAGP 442

Query: 219 PVPPVPPI-PPVPSVPPMTP 237
            +PP   I  P P  PP +P
Sbjct: 443 HIPPSDEICEPGPPGPPGSP 462



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 30/101 (29%), Positives = 37/101 (36%), Gaps = 21/101 (20%)

Query: 186  PPPPIPPIPAMPSL---------PPMPSIPPIPVPPPVPTLPPVPPVPPI---PPVPSVP 233
            P  P PP P  P+L         P +P IP +  P     LP  P  P +   P +P  P
Sbjct: 946  PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005

Query: 234  PMTPLPPMSGMPPLNPPPVA---------PLPAGMNGSGAP 265
                 P + G P L  PP           P P G+ G   P
Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGP 1046



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 28/89 (31%), Positives = 35/89 (39%), Gaps = 9/89 (10%)

Query: 187  PPPIPPIPAMPS---LPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLPPMSG 243
            PP +P +        LP +P  P +P P   P     P V      P  PP +P P + G
Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQG----PPGPPGSPGPALEG 1249

Query: 244  MPPLNPPPVAPL-PAGMNGSGAPMNLNNN 271
             P  NP P  P    G+ G   P  L  N
Sbjct: 1250 -PKGNPGPQGPPGRPGLPGPEGPPGLPGN 1277



 Score = 31.2 bits (69), Expect = 4.7
 Identities = 23/89 (25%), Positives = 33/89 (37%), Gaps = 17/89 (19%)

Query: 194  PAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLPPMSGMPPLNPPPVA 253
            P  P LP +P +     PP +   P  P +  +   P +P +   P M G          
Sbjct: 1287 PGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKG---------- 1336

Query: 254  PLPAGMNGSGAPMNLNNNLNPMFLGPLNP 282
              P+G+ GS  P        P  +GP  P
Sbjct: 1337 --PSGVPGSAGPEG-----EPGLIGPPGP 1358


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
           sapiens]
          Length = 1688

 Score =  101 bits (251), Expect = 4e-21
 Identities = 97/247 (39%), Positives = 110/247 (44%), Gaps = 49/247 (19%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMP----NAGLPGVGLPSAGLPGA-GLPSTGLPGSAITSA 685
           P  +G  G  +  PG P +PG P    + GLPG      GLPG  GLP  G+PGS     
Sbjct: 649 PGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPG----DPGLPGQPGLP--GIPGSK-GEP 701

Query: 686 GLPGAGMPSA----GIPSAGGEEHAFLTVG--SKEANNGPPFNFPGNFG--GSNAFGPPI 737
           G+PG G+P      G P   G   A  T G    E   GPP  FPG  G  G    GPP 
Sbjct: 702 GIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPP-GFPGPKGEPGFALPGPPG 760

Query: 738 PP--PGLGG--GAFGDAR-PGMPSV-GNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQN 791
           PP  PG  G  G  GD   PG P   G +GL GL         GP    GP+G       
Sbjct: 761 PPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP--------GPKGDVGPNG------- 805

Query: 792 FGNGPGSLGGP--PGFG-SGPPGLGSAPGHLGGPPAFG-PGPGPGPGPGPIHIGGPPGFA 847
               PG +G P  PG G  GPPG    PG +G P   G PG    PGP  + + GPPG  
Sbjct: 806 ---QPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGER 862

Query: 848 SSSGKPG 854
            S G PG
Sbjct: 863 GSPGIPG 869



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 101/259 (38%), Positives = 111/259 (42%), Gaps = 53/259 (20%)

Query: 631  PPAQGKKGLKMP--VPGNPAVPGMP-------NAGLPGVGLPSAGLPGA----GLPS-TG 676
            P  QG +G   P  VPG P  PG+P       + G+  +GLP  GLPG     GLP   G
Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLP--GLPGPKGEPGLPGYPG 1092

Query: 677  LPG--SAITSAGLPGA-GMPSA-GIPSAGGEEHAFLTVGSKEANNGPPFN-----FPGNF 727
             PG   ++   GLPG  G P A G P   G        G K  + GPP N      PG  
Sbjct: 1093 NPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS-GPPGNPGLPGEPGPV 1151

Query: 728  GGSNAFGPPIPP--------PGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNL 779
            GG    G P PP         G+ G A     PG P  GN G PGL    PG       L
Sbjct: 1152 GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL----PG-------L 1200

Query: 780  SGPSGFGGGPQNFGNGPGSLG--GPPGFGSGPPGLGSAPGHLGGPPAFGPG-PGPGPGPG 836
            SG  G GG P   GN PG  G  G PGF  G PG+   PG  G P   GP   GP   PG
Sbjct: 1201 SGQKGDGGLPGIPGN-PGLPGPKGEPGF-HGFPGVQGPPGPPGSP---GPALEGPKGNPG 1255

Query: 837  PIHIGGPPGFASSSGKPGP 855
            P    G PGF    G  GP
Sbjct: 1256 PQGPPGRPGFQGLPGPEGP 1274



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 99/293 (33%), Positives = 115/293 (39%), Gaps = 79/293 (26%)

Query: 631  PPAQGKKGLK-MPVPGNPAVPGMPNA-GLPGV-GLPSA-GLPGA-GLPSTGLPGSAITSA 685
            P   G  GL  + V G P  PG+P   G PG+ G+P   G PG  GL   G PG    S 
Sbjct: 807  PGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGER-GSP 865

Query: 686  GLPGAGMP-----SAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPP- 739
            G+PGA  P     S G+P   G                    FPG  G     GPP PP 
Sbjct: 866  GIPGAPGPIGPPGSPGLPGKAGAS-----------------GFPGTKGEMGMMGPPGPPG 908

Query: 740  ----------PGLGGGAFGDARPGMP-------SVGNSGLPG---------LGLD----V 769
                      PGL G      +PG+P       S G  GLPG         LG       
Sbjct: 909  PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGE 968

Query: 770  PGFGGGPNNLSGPSGFGGGPQNFG----NGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAF 825
            PG  G P  +SGP G+ G P + G    +G   L GPPG   G PGL   PG +G P   
Sbjct: 969  PGLPGIPG-VSGPKGYQGLPGDPGQPGLSGQPGLPGPPG-PKGNPGLPGQPGLIGPPGLK 1026

Query: 826  G-------PGPG-----PGPGPGPIHIGGP--PGFASSSGKPGPTVIKVQNMP 864
            G       PGP      PGP   P   G P  PG     G PG + I +  +P
Sbjct: 1027 GTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLP 1079



 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 92/278 (33%), Positives = 109/278 (39%), Gaps = 73/278 (26%)

Query: 631  PPAQGKKGLK-MP-VPGNPAVPGMPNA----GLPGV-------GLPSAGLPGA-GLPSTG 676
            P   G+KG   +P +PGNP +PG        G PGV       G P   L G  G P   
Sbjct: 1198 PGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ 1257

Query: 677  LPGSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPP 736
             P       GLPG   P  G+P  GG       +  ++ N G P   PG  G     GPP
Sbjct: 1258 GPPGRPGFQGLPGPEGPP-GLPGNGG-------IKGEKGNPGQP-GLPGLPGLKGDQGPP 1308

Query: 737  IPPPGLGGGAFGDARPGMPSV-GNSGLPGLGLDVPGFGG--GPNNLSGPSGFGGGPQNFG 793
                GL G      RPG+  + G+ GLPG    VPGF G  GP+ + G +G  G P   G
Sbjct: 1309 ----GLQGNP---GRPGLNGMKGDPGLPG----VPGFPGMKGPSGVPGSAGPEGEPGLIG 1357

Query: 794  N-GPGSLGGPPGFG------SGPPGLGSAPGHLGGPPAFGPGPGPGPG------------ 834
              GP  L GP G        +GPPG+   PG  G P   GP   PGP             
Sbjct: 1358 PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP 1417

Query: 835  -----------------PGPIHIGGPPGFASSSGKPGP 855
                             PG   + GPPG     G PGP
Sbjct: 1418 GFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGP 1455



 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 95/274 (34%), Positives = 110/274 (40%), Gaps = 66/274 (24%)

Query: 631  PPAQGKKGLKMPV--PGNPAVPGMPNA-GLPGVG--LPSAGLPGA----GLPS-TGLPGS 680
            P   G+ GL  P    GNP +PG P   G PG+   +   G PG     G P  +G+PG 
Sbjct: 993  PGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQ 1052

Query: 681  AITSAGLPGA-------GMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAF 733
               S GLPG        G+ S G+P   G +             G P  +PGN G   + 
Sbjct: 1053 P-GSPGLPGQKGDKGDPGISSIGLPGLPGPK----------GEPGLP-GYPGNPGIKGSV 1100

Query: 734  GPPIPPPGLGGGAFGDARPGMPSV----------------GNSGLPGLGLDVPGFGGGPN 777
            G P   PGL G      +PG+P                  GN GLPG     P  GGG  
Sbjct: 1101 GDP-GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGE--PGPVGGGGHP 1157

Query: 778  NLSGPSGFGGGPQNFGNGPGSLG-----GPPGFGS-GPPGLGSAPGHLG--GPPAFGPGP 829
               GP G  G P   G  PG  G     G PGFG+ GPPGL    G  G  G P     P
Sbjct: 1158 GQPGPPGEKGKPGQDGI-PGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNP 1216

Query: 830  G-PGPGPGPIHIG-----GPPGFASSSGKPGPTV 857
            G PGP   P   G     GPPG     G PGP +
Sbjct: 1217 GLPGPKGEPGFHGFPGVQGPPG---PPGSPGPAL 1247



 Score = 81.3 bits (199), Expect = 4e-15
 Identities = 79/220 (35%), Positives = 88/220 (40%), Gaps = 42/220 (19%)

Query: 645  GNPAVPGMPNAGLPGVGLPSA--GLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGG 702
            G    PG+P  G+PGV  P    GLPG      G PG +    GLPG   P  G P   G
Sbjct: 964  GEKGEPGLP--GIPGVSGPKGYQGLPG----DPGQPGLS-GQPGLPGPPGPK-GNPGLPG 1015

Query: 703  EEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPP-----PGLGGGAFGDARPGMPSV 757
            +       G K         FPG  G     GP   P     PGL G       PG+ S+
Sbjct: 1016 QPGLIGPPGLKGTIGD--MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI 1073

Query: 758  GNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPG 817
            G  GLPG           P    G  G+ G P       GS+G P     G PGL   PG
Sbjct: 1074 GLPGLPG-----------PKGEPGLPGYPGNP----GIKGSVGDP-----GLPGLPGTPG 1113

Query: 818  HLGGP--PAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGP 855
              G P  P F   PGP   PGP  I GPPG     G+PGP
Sbjct: 1114 AKGQPGLPGFPGTPGP---PGPKGISGPPGNPGLPGEPGP 1150



 Score = 80.9 bits (198), Expect = 5e-15
 Identities = 87/254 (34%), Positives = 99/254 (38%), Gaps = 36/254 (14%)

Query: 631  PPAQGKKGLKMPVPGNPAVPGMPNA-GLPGVGLPSA--GLPGAG--LPSTGLPGSAITSA 685
            P   G KG +  +PG+P  PG+    GLPG   P    GLPG    +   GL G+ I   
Sbjct: 975  PGVSGPKGYQ-GLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT-IGDM 1032

Query: 686  GLPGA----GMPS-AGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPP- 739
            G PG     G P  +G+P   G        G K          PG  G     G P  P 
Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPG 1092

Query: 740  -PGLGGGAFGDARPGMPSV-GNSGLPGLGLDVPGFGG-----GPNNLSGPSG-------- 784
             PG+ G       PG+P   G  G PGL    PGF G     GP  +SGP G        
Sbjct: 1093 NPGIKGSVGDPGLPGLPGTPGAKGQPGL----PGFPGTPGPPGPKGISGPPGNPGLPGEP 1148

Query: 785  --FGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPG-PGPIHIG 841
               GGG      GP    G PG   G PG     G  G P    PGP   PG  G    G
Sbjct: 1149 GPVGGGGHPGQPGPPGEKGKPG-QDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDG 1207

Query: 842  GPPGFASSSGKPGP 855
            G PG   + G PGP
Sbjct: 1208 GLPGIPGNPGLPGP 1221



 Score = 80.9 bits (198), Expect = 5e-15
 Identities = 108/301 (35%), Positives = 116/301 (38%), Gaps = 86/301 (28%)

Query: 631  PPAQGKKGLKMPVPGNPAVPGMP-------NAGLPGV----------GLPSA-------G 666
            P   G KG+  P PGNP +PG P       + G PG           G+P         G
Sbjct: 1127 PGPPGPKGISGP-PGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG 1185

Query: 667  LPGAGLPST-GLPGSAITSA--GLPGA-GMPSAGIPSAGGEE--HAFLTV-------GSK 713
             PG G P   GLPG +      GLPG  G P  G+P   GE   H F  V       GS 
Sbjct: 1186 QPGFGNPGPPGLPGLSGQKGDGGLPGIPGNP--GLPGPKGEPGFHGFPGVQGPPGPPGSP 1243

Query: 714  -EANNGP-----PFNFPGNFGGSNAFGPPIPP--PGLGGGAFGDARPGMPSVGNSGLPGL 765
              A  GP     P   PG  G     GP  PP  PG GG       PG P  G  GLPGL
Sbjct: 1244 GPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQP--GLPGLPGL 1301

Query: 766  GLDV--PGFGGGP-----NNLSGPSGFGGGPQNFG-----NGPGSLG--GPPGFGSGPPG 811
              D   PG  G P     N + G  G  G P   G       PGS G  G PG   GPPG
Sbjct: 1302 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGL-IGPPG 1360

Query: 812  LGSAPGHLG---------GPPAFGPGPG----PGPG-----PGPIHIGGPPGFASSSGKP 853
                PG  G         GPP     PG    PGP      PGP    GPPG    +G P
Sbjct: 1361 PPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPT---GPPGDPGRNGLP 1417

Query: 854  G 854
            G
Sbjct: 1418 G 1418



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 83/236 (35%), Positives = 91/236 (38%), Gaps = 60/236 (25%)

Query: 644 PGNPAVPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSA--GLPGA-GMPSA-GIPS 699
           PG P +PG+P  G PG    S G PG      G  G A  +   GLPG  G P A G P 
Sbjct: 493 PGQPGLPGLP--GPPG----SLGFPG----QKGEKGQAGATGPKGLPGIPGAPGAPGFPG 542

Query: 700 AGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPP--PGLGGGAFGDARPGMPSV 757
           + GE    LT             FPG  G     G P  P  PGL G    D  PG+P  
Sbjct: 543 SKGEPGDILT-------------FPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLP-- 587

Query: 758 GNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGS-GPPGLGSAP 816
           G  G PG G+   G  G P N     G  G P N G       GPPGFG  GP G     
Sbjct: 588 GPKGEPG-GITFKGERGPPGN----PGLPGLPGNIGPM-----GPPGFGPPGPVGEKGIQ 637

Query: 817 GHLGGPPAFG-PGPGPGPGP-----------------GPIHIGGPPGFASSSGKPG 854
           G  G P   G PGP   PG                  G + + G PG     G PG
Sbjct: 638 GVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG 693



 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 95/310 (30%), Positives = 115/310 (37%), Gaps = 60/310 (19%)

Query: 631 PPAQGKKGLKMP--VPGNPAVPGMPNAGLPGV-GLPSA-GLPGAG--LPSTGLPGSAITS 684
           P   G KG++ P  +PG P  PG+P  G+PG  G P   G+PG        G PGS    
Sbjct: 83  PGPPGPKGIRGPPGLPGFPGTPGLP--GMPGHDGAPGPQGIPGCNGTKGERGFPGSP--- 137

Query: 685 AGLPGAGMPSA--GIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGP-----PI 737
            G PG   P    GIP   GE  + + + S     G P  +PG  G     GP     PI
Sbjct: 138 -GFPGLQGPPGPPGIPGMKGEPGSII-MSSLPGPKGNP-GYPGPPGIQGLPGPTGIPGPI 194

Query: 738 PPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSG------------- 784
            PPG  G       PG+P  G  G  GL    P    G   L GP G             
Sbjct: 195 GPPGPPGLMGPPGPPGLP--GPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252

Query: 785 --FGGGPQNFGNGPGSLG--------GPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPG-- 832
             F  G Q      G  G        GPPG   G  G    PG  G P   G    PG  
Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 833 -----PG-PGPIHIGGPPGFASSSGKPGPTVIKVQNMPFTVSIDEILDFFYGYQVIPGSV 886
                PG PG     G  G    +G PGP  + +      ++I E  +   G   +PG  
Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNI--GLPGLPG-- 368

Query: 887 CLKYNEKGMP 896
             +  E+G P
Sbjct: 369 --EKGERGFP 376



 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 95/286 (33%), Positives = 107/286 (37%), Gaps = 71/286 (24%)

Query: 631 PPAQGKKGLKMP----VPGNPAVPGMP-------NAGLPGVGLPSA----GLPGA-GLPS 674
           P  QG  GL  P    V G P  PG P       + G PG+ +P      G PGA GLP 
Sbjct: 376 PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLP- 434

Query: 675 TGLPGSA---------ITSAGLPGA-GMPS-------AGIPSAGGEEHAFLTVGSKEANN 717
            G PG A         I   G PG  G P         G+    G+   F  +G+  +  
Sbjct: 435 -GPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT-CFNCIGTGISGP 492

Query: 718 ----------GPP--FNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGL 765
                     GPP    FPG  G     G    P GL G       PG P  G+ G PG 
Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGAT-GPKGLPGIPGAPGAPGFP--GSKGEPGD 549

Query: 766 GLDVPGFGGGPNNLSGPS-----GFGGGPQNFG--NGPGSLGGPPGFG-------SGPPG 811
            L  PG  G    L  P      G  G P   G    PG  G P G          G PG
Sbjct: 550 ILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609

Query: 812 LGSAPGHLG--GPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGP 855
           L   PG++G  GPP FGP PGP    G   + G PG     G PGP
Sbjct: 610 LPGLPGNIGPMGPPGFGP-PGPVGEKGIQGVAGNPG---QPGIPGP 651



 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 81/224 (36%), Positives = 88/224 (39%), Gaps = 42/224 (18%)

Query: 657 LPGVGLPSAGLPGAGLPSTGLPGSAITSAGL-PGAGMPSAGIPSAGGEEHAFLTVGSKEA 715
           L GV L +AGL    L   G P  A    G  PG+    +GI    GE          E 
Sbjct: 3   LRGVSL-AAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERG----FPGLEG 57

Query: 716 NNGPPFNFPGNFGGSNAFGPP----IP-PPGLGGGAFGDARPGMPSVGNSGLPGLGLDVP 770
           + G P  FPG  G     G      IP PPG  G       PG P  G  GLPG+    P
Sbjct: 58  HPGLP-GFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP--GTPGLPGM----P 110

Query: 771 GFGGGPNNLSGPSGFGG-----GPQNFGNGPGSLG-----GPPGFGS--GPPG---LGSA 815
           G  G P    GP G  G     G + F   PG  G     GPPG     G PG   + S 
Sbjct: 111 GHDGAP----GPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSL 166

Query: 816 PGHLG-----GPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPG 854
           PG  G     GPP     PGP   PGPI   GPPG     G PG
Sbjct: 167 PGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 86/249 (34%), Positives = 100/249 (40%), Gaps = 60/249 (24%)

Query: 611  GREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPAVPGMP----NAGLPGV-GLPSA 665
            GR  F  +   E    +  N   +G+KG     PG P +PG+P    + G PG+ G P  
Sbjct: 1261 GRPGFQGLPGPEGPPGLPGNGGIKGEKGN----PGQPGLPGLPGLKGDQGPPGLQGNP-- 1314

Query: 666  GLPGAG--LPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNF 723
            G PG        GLPG      G PG   PS G+P + G E     +G      GPP   
Sbjct: 1315 GRPGLNGMKGDPGLPGVP----GFPGMKGPS-GVPGSAGPEGEPGLIGPP----GPP-GL 1364

Query: 724  PGNFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPS 783
            PG  G S        PPG+         PG P  G  GLPG          GP  L GP+
Sbjct: 1365 PGPSGQSIIIKGDAGPPGI---------PGQP--GLKGLPG--------PQGPQGLPGPT 1405

Query: 784  GFGGGPQNFGNGPGSLGGPPGFGS--GPPGLGSAPGHLG--GPPAFGPGPGPGPGPGPIH 839
            G  G P     G   L G  G G   G PGL   PG  G  GPP  GP    GP      
Sbjct: 1406 GPPGDP-----GRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPP--GPDGLQGP------ 1452

Query: 840  IGGPPGFAS 848
              GPPG +S
Sbjct: 1453 -PGPPGTSS 1460



 Score = 67.4 bits (163), Expect = 6e-11
 Identities = 85/259 (32%), Positives = 96/259 (37%), Gaps = 61/259 (23%)

Query: 626 EIEKNPPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSAGLPGA----GLPSTGLPGSA 681
           ++E     QG  G + P PG P + G P  G PG      G  G     G P        
Sbjct: 252 DVEFQKGDQGLPGDRGP-PGPPGIRGPP--GPPGGEKGEKGEQGEPGKRGKPGKDGENGQ 308

Query: 682 ITSAGLPG-AGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPP---I 737
               GLPG  G P  G P   GE+        ++ + GPP             GPP   I
Sbjct: 309 PGIPGLPGDPGYP--GEPGRDGEK-------GQKGDTGPP-------------GPPGLVI 346

Query: 738 PPPGLG---GGAFGDARPGMPSV-GNSGLPGLGLDVPGFGGGPNNLSGPSGFG----GGP 789
           P PG G   G       PG+P   G  G PG+         GP  L GP G       GP
Sbjct: 347 PRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQ--------GPPGLPGPPGAAVMGPPGP 398

Query: 790 QNFGNGPGSLG--GPPGFG-SGPPGLGSAPGHLGGPPAFGP-GPGPGPG-----PGPIHI 840
             F    G  G  GPPG    GPPGL   PG  G P   GP GP   P      PGP   
Sbjct: 399 PGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP--- 455

Query: 841 GGPPGFASSSGKPGPTVIK 859
            GPPG     G  G   +K
Sbjct: 456 PGPPGSPGDKGLQGEQGVK 474



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 79/260 (30%), Positives = 94/260 (36%), Gaps = 48/260 (18%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSAGLPG--AGLPSTGLPGSAITSAGLP 688
           P  +G++G    + G P +PG P A + G   P  G PG        G PG +I   G P
Sbjct: 367 PGEKGERGFP-GIQGPPGLPGPPGAAVMGPPGPP-GFPGERGQKGDEGPPGISIP--GPP 422

Query: 689 GA-GMPSA-GIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPP--PGLGG 744
           G  G P A G+P   G     +    +    GPP             GPP  P   GL G
Sbjct: 423 GLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPP-------------GPPGSPGDKGLQG 469

Query: 745 -----GAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSL 799
                G  GD        G SG PG    +PG  G P +L  P   G   Q    GP  L
Sbjct: 470 EQGVKGDKGDTCFNCIGTGISGPPGQP-GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGL 528

Query: 800 GGPPGFGSGP---------------PGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPP 844
            G PG    P               PG+    G LG P A    PG    PG     G P
Sbjct: 529 PGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGA----PGLPGLPGTPGQDGLP 584

Query: 845 GFASSSGKPGPTVIKVQNMP 864
           G     G+PG    K +  P
Sbjct: 585 GLPGPKGEPGGITFKGERGP 604



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 85/266 (31%), Positives = 98/266 (36%), Gaps = 56/266 (21%)

Query: 634 QGKKGLKMPVPGNPAVPGMPNA-GLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPG-AG 691
           +G++G    + G+P +PG P   G PG   P       G+P    P       GLPG  G
Sbjct: 47  KGERGFP-GLEGHPGLPGFPGPEGPPG---PRGQKGDDGIPGPPGPKGIRGPPGLPGFPG 102

Query: 692 MPSAGIPSAGGEEHAFLTVGSKEANNGP-PFNFPGNFGGSNAFGPPIPP--PGLGG---- 744
            P  G+P   G + A    G    N       FPG+ G     GPP PP  PG+ G    
Sbjct: 103 TP--GLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGS 160

Query: 745 -------GAFGDARPGMPSV-GNSGLPG-LGLDVPGFGGGPNNLSGPSGFGGGPQNFGN- 794
                  G  G+  PG P   G  GLPG  G+  P    GP  L GP G  G P   GN 
Sbjct: 161 IIMSSLPGPKGN--PGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNM 218

Query: 795 -----------GPGSLGGPPG---------------FGSGPPGLGSAPGHLGGPPAFGPG 828
                      G   L GPPG               F  G  GL    G  G P   GP 
Sbjct: 219 GLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP- 277

Query: 829 PGPGPGPGPIHIGGPPGFASSSGKPG 854
             PGP  G     G  G     GKPG
Sbjct: 278 --PGPPGGEKGEKGEQGEPGKRGKPG 301



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 35/128 (27%), Positives = 42/128 (32%), Gaps = 20/128 (15%)

Query: 160  PNMGASFGSPTFSSTVPSTA--SPMNTVPPPPIPPIPAMPSLPPMPS------------- 204
            P      G P    T+       P     PP    +P  P  P +P              
Sbjct: 1014 PGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI 1073

Query: 205  -IPPIPVPPPVPTLPPVPPVPPIPPV---PSVPPMTPLPPMSGMPPLNPPPVAPLPAGMN 260
             +P +P P   P LP  P  P I      P +P +   P   G P L   P  P P G  
Sbjct: 1074 GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK 1133

Query: 261  G-SGAPMN 267
            G SG P N
Sbjct: 1134 GISGPPGN 1141



 Score = 38.9 bits (89), Expect = 0.023
 Identities = 38/148 (25%), Positives = 47/148 (31%), Gaps = 47/148 (31%)

Query: 175 VPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTL----------------- 217
           +P    P     PP +P  P  P LP MP     P P  +P                   
Sbjct: 82  IPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141

Query: 218 ---PPVPPVPP-------------------IPPVPSVPPMTPLPPMSGMP-PLNPPPVAP 254
              PP PP  P                    P  P  P +  LP  +G+P P+ PP    
Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPG--- 198

Query: 255 LPAGMNGSGAPMNL---NNNLNPMFLGP 279
            P G+ G   P  L     N+   F GP
Sbjct: 199 -PPGLMGPPGPPGLPGPKGNMGLNFQGP 225



 Score = 38.9 bits (89), Expect = 0.023
 Identities = 37/145 (25%), Positives = 49/145 (33%), Gaps = 14/145 (9%)

Query: 160 PNMGASFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVP---T 216
           P    S G P    T P        +  P  P +P +P  P    +P +P P   P   T
Sbjct: 538 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT 597

Query: 217 LPPVPPVPPIPPVPSVPPMTPLPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMF 276
                  P  P +P +P          + P+ PP   P P  +   G      N   P  
Sbjct: 598 FKGERGPPGNPGLPGLP--------GNIGPMGPPGFGP-PGPVGEKGIQGVAGNPGQPGI 648

Query: 277 LGPLNPVNPIQMNSQSSVKPLPINP 301
            GP    +P Q  +Q     LP NP
Sbjct: 649 PGPKG--DPGQTITQPGKPGLPGNP 671



 Score = 38.9 bits (89), Expect = 0.023
 Identities = 39/151 (25%), Positives = 51/151 (33%), Gaps = 31/151 (20%)

Query: 159 PPNMGASFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLP 218
           PP +    G P     +P         P PP   +P  P     P IP  P P   P  P
Sbjct: 826 PPGIPGPIGQPGLHG-IPGEKGD----PGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSP 880

Query: 219 PVPPV-----------------PPIPPVP-SVPPMTPLPPMSGMPPLNPPPVAPLPAGMN 260
            +P                   PP PP P  +P  + +P + G   L   P  P P G  
Sbjct: 881 GLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEK 940

Query: 261 GSGAPMNLNNNLNPMFLGPLNPVNPIQMNSQ 291
           GS           P   GP  P++P  + S+
Sbjct: 941 GSKG--------EPGLPGPPGPMDPNLLGSK 963



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 28/99 (28%), Positives = 36/99 (36%), Gaps = 1/99 (1%)

Query: 167 GSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPI 226
           G+P           P  T+  P  P +P  P       +P  P  P  P LP +P     
Sbjct: 641 GNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGE 700

Query: 227 PPVPSVPPMTPLPPMSGMPPLNPPPVAPLPAGMNGSGAP 265
           P +P +    P P   G P +  PP AP   G  G   P
Sbjct: 701 PGIPGIGLPGP-PGPKGFPGIPGPPGAPGTPGRIGLEGP 738



 Score = 37.0 bits (84), Expect = 0.086
 Identities = 44/176 (25%), Positives = 55/176 (31%), Gaps = 30/176 (17%)

Query: 98   PPANASRSGPPPSSGMSSRVNLPTTVSNFNNPSPSVVTATTSVHESNKNIQTFSTASVGT 157
            PP      G P   G+     L  T+ +   P P  V                       
Sbjct: 1004 PPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPG------------------ 1045

Query: 158  APPNMGASFGSPTFSSTVPSTASP-MNTVPPPPIPPIPAMPSLPPMPSIPPI------PV 210
             P  +    GSP           P ++++  P +P     P LP  P  P I      P 
Sbjct: 1046 -PSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPG 1104

Query: 211  PPPVPTLPPVPPVPPIPPVPSVPPMTPLPPMSGMPPLNPP-PVAPLPAGMNGSGAP 265
             P +P  P     P +P  P  P   P P     PP NP  P  P P G  G G P
Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPG-PPGPKGISGPPGNPGLPGEPGPVG--GGGHP 1157



 Score = 35.8 bits (81), Expect = 0.19
 Identities = 43/146 (29%), Positives = 52/146 (35%), Gaps = 25/146 (17%)

Query: 188 PPIPPIPAMPSLPPMPSIPPIPVPPPVPTLP-----PVPPVPPIPPVPSVPPMTPLPPMS 242
           P IP I  +P  P     P IP PP  P  P       PP PP  P P   P   LP   
Sbjct: 701 PGIPGI-GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPP 759

Query: 243 GMP-------PLNP--------PPVAPLPAGMNGSGAPM-NLNNNLNPMFLGPLNPVNPI 286
           G P        L P        PP  P   G++G   P  ++  N  P   GP+ P    
Sbjct: 760 GPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQP---GPMGPPGLP 816

Query: 287 QMNSQSSVKPLPINPDDLYVSVHGMP 312
            +  Q    P  I        +HG+P
Sbjct: 817 GIGVQGPPGPPGIPGPIGQPGLHGIP 842



 Score = 35.0 bits (79), Expect = 0.33
 Identities = 28/80 (35%), Positives = 32/80 (40%), Gaps = 5/80 (6%)

Query: 159 PPNMGASFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLP 218
           PP  GA+   P      P          PP I  IP  P L   P  P +P  PP P  P
Sbjct: 387 PP--GAAVMGPPGPPGFPGERGQKGDEGPPGIS-IPGPPGLDGQPGAPGLP-GPPGPAGP 442

Query: 219 PVPPVPPI-PPVPSVPPMTP 237
            +PP   I  P P  PP +P
Sbjct: 443 HIPPSDEICEPGPPGPPGSP 462



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 30/101 (29%), Positives = 37/101 (36%), Gaps = 21/101 (20%)

Query: 186  PPPPIPPIPAMPSL---------PPMPSIPPIPVPPPVPTLPPVPPVPPI---PPVPSVP 233
            P  P PP P  P+L         P +P IP +  P     LP  P  P +   P +P  P
Sbjct: 946  PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005

Query: 234  PMTPLPPMSGMPPLNPPPVA---------PLPAGMNGSGAP 265
                 P + G P L  PP           P P G+ G   P
Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGP 1046



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 27/88 (30%), Positives = 32/88 (36%), Gaps = 4/88 (4%)

Query: 187  PPPIPPIPAMPS---LPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLPPMSG 243
            PP +P +        LP +P  P +P P   P     P V   PP P   P   L    G
Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQG-PPGPPGSPGPALEGPKG 1252

Query: 244  MPPLNPPPVAPLPAGMNGSGAPMNLNNN 271
             P    PP  P   G+ G   P  L  N
Sbjct: 1253 NPGPQGPPGRPGFQGLPGPEGPPGLPGN 1280



 Score = 31.2 bits (69), Expect = 4.7
 Identities = 23/89 (25%), Positives = 33/89 (37%), Gaps = 17/89 (19%)

Query: 194  PAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLPPMSGMPPLNPPPVA 253
            P  P LP +P +     PP +   P  P +  +   P +P +   P M G          
Sbjct: 1290 PGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKG---------- 1339

Query: 254  PLPAGMNGSGAPMNLNNNLNPMFLGPLNP 282
              P+G+ GS  P        P  +GP  P
Sbjct: 1340 --PSGVPGSAGPEG-----EPGLIGPPGP 1361


>gi|126352608 elastin isoform e precursor [Homo sapiens]
          Length = 705

 Score = 95.1 bits (235), Expect = 3e-19
 Identities = 82/229 (35%), Positives = 103/229 (44%), Gaps = 47/229 (20%)

Query: 649 VPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFL 708
           VPG P  G   VG+P AG+PG G+P  G+P   +  AG+PGA +P    P A  +     
Sbjct: 323 VPGGPGFGPGVVGVPGAGVPGVGVPGAGIP--VVPGAGIPGAAVPGVVSPEAAAK----- 375

Query: 709 TVGSKEANNGPPFNFPG-NFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGL 767
              +K A  G     PG   GG       IP  G+G G F    PG   VG  G+PG+  
Sbjct: 376 -AAAKAAKYGAR---PGVGVGG-------IPTYGVGAGGF----PGF-GVGVGGIPGVA- 418

Query: 768 DVPGFGGGPNNLSGPSGFGGGPQ----------NFGNGPGSLGGPPGFGSGP-----PGL 812
            VPG GG P  + G  G G  P+           +G  PG +G  PG G  P     PG+
Sbjct: 419 GVPGVGGVP-GVGGVPGVGISPEAQAAAAAKAAKYGLVPG-VGVAPGVGVAPGVGVAPGV 476

Query: 813 GSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGPTVIKVQ 861
           G APG +G  P  G  PG G  PG     GP G A+++        K Q
Sbjct: 477 GLAPG-VGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAKVAAKAQ 520



 Score = 70.1 bits (170), Expect = 9e-12
 Identities = 80/271 (29%), Positives = 107/271 (39%), Gaps = 55/271 (20%)

Query: 632 PAQGKKGLKMPVPGNPAVPG--MPNAGLPGVGLPSA--------------------GLPG 669
           P  G  G+ +P  G P VPG  +P A +PGV  P A                    G+P 
Sbjct: 337 PGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPT 396

Query: 670 AGLPSTGLPGSAITSAGLPG-AGMPSAG-IPSAGGEEHAFLTVGSKEANNGPPFNFPGNF 727
            G+ + G PG  +   G+PG AG+P  G +P  GG     ++  ++ A       +    
Sbjct: 397 YGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVP 456

Query: 728 GGSNAFGPPIPPPGLGGGAFGDARPGM---PSVGNSGLPGLGLDVPGFGGG--------- 775
           G   A G  + P G+G        PG+   P VG +  PG+G+  PG G G         
Sbjct: 457 GVGVAPGVGVAP-GVGVAPGVGLAPGVGVAPGVGVA--PGVGV-APGIGPGGVAAAAKSA 512

Query: 776 -----PNNLSGPSGFGGGPQNFGNGPGSLG-----GPPGFG--SGPPGLGSAPGHLGGPP 823
                   L   +G G G    G G G  G     G PG G  +G PG G+ PG L    
Sbjct: 513 AKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAK 572

Query: 824 AFGPG---PGPGPGPGPIHIGGPPGFASSSG 851
           A   G   PG   G G +   G PG    +G
Sbjct: 573 AAKYGAAVPGVLGGLGALGGVGIPGGVVGAG 603



 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 70/223 (31%), Positives = 88/223 (39%), Gaps = 51/223 (22%)

Query: 638 GLKMPVPGNPAVPG-MPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGL----PGAGM 692
           G  +P PG    PG +P  GLPGV  P   LPGA  P  G+     T AG+    PG G 
Sbjct: 126 GAVVPQPGAGVKPGKVPGVGLPGV-YPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 184

Query: 693 PSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAFGDARP 752
             AGIP  G                         FGG        P PG+  G +    P
Sbjct: 185 AFAGIPGVGP------------------------FGG--------PQPGVPLG-YPIKAP 211

Query: 753 GMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPG-----FGS 807
            +P  G  GLP     +P +G GP  ++G +G  G P   G GP +           FG+
Sbjct: 212 KLP--GGYGLPYTTGKLP-YGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGA 268

Query: 808 GPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSS 850
           G  G+    G  G P      PG  PG G I   G P  A+++
Sbjct: 269 GAAGVLPGVGGAGVPGV----PGAIPGIGGIAGVGTPAAAAAA 307



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 61/184 (33%), Positives = 74/184 (40%), Gaps = 25/184 (13%)

Query: 665 AGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFP 724
           AG+PG G+   G+PG  +  AG+PG G+  AG+P  G    A     +K A  G     P
Sbjct: 529 AGIPGLGV-GVGVPGLGV-GAGVPGLGV-GAGVPGFGAVPGAL--AAAKAAKYGAAV--P 581

Query: 725 GNFGGSNAFGPPIPPPGLGGG------AFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNN 778
           G  GG  A G    P G+ G       A   A       G  G  GLG    G G G   
Sbjct: 582 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLG----GLGVGGLG 637

Query: 779 LSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPI 838
           + G  G GG P      P +      +G+   GLG   G  G  P  G    PG G  PI
Sbjct: 638 VPGVGGLGGIP------PAAAAKAAKYGAA--GLGGVLGGAGQFPLGGVAARPGFGLSPI 689

Query: 839 HIGG 842
             GG
Sbjct: 690 FPGG 693



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 73/243 (30%), Positives = 90/243 (37%), Gaps = 46/243 (18%)

Query: 635 GKKGLKMPVPGNPAVPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPS 694
           G K LK PVPG     G+  AGL G GL     P    P   +PG    +A    A    
Sbjct: 59  GGKPLK-PVPG-----GLAGAGL-GAGL--GAFPAVTFPGALVPGGVADAAAAYKAAKAG 109

Query: 695 AGIPSAGGEEHAFLTVGSKEANNG--------PPFNFPGNFGGSNAFGPPIPP----PGL 742
           AG+    G     ++ G+     G        P    PG + G    G   P     PG+
Sbjct: 110 AGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGV 169

Query: 743 GGGAFGDARPGMPSVGN--SGLPGLGLDVPGFGGGPNNLSG--------PSGFG----GG 788
             GA    +P  P VG   +G+PG+G   P  G  P    G        P G+G     G
Sbjct: 170 PTGA--GVKPKAPGVGGAFAGIPGVG---PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTG 224

Query: 789 PQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPA-----FGPG-PGPGPGPGPIHIGG 842
              +G GPG + G  G    P G G  P       A     FG G  G  PG G   + G
Sbjct: 225 KLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPG 284

Query: 843 PPG 845
            PG
Sbjct: 285 VPG 287



 Score = 57.0 bits (136), Expect = 8e-08
 Identities = 82/260 (31%), Positives = 103/260 (39%), Gaps = 41/260 (15%)

Query: 646 NPAVPGMPNAGLPGVGLPSAGL-PGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEE 704
           +P+ PG     +PG G+P     PGAGL + G  G A+   G P   +P       GG  
Sbjct: 22  HPSRPGGVPGAIPG-GVPGGVFYPGAGLGALG--GGALGPGGKPLKPVP-------GGLA 71

Query: 705 HAFLTVGSKEANNGPPFNFPGNF-GGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGL- 762
            A L  G       P   FPG    G  A           G   G    G+P VG  G+ 
Sbjct: 72  GAGLGAG---LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLG----GVPGVGGLGVS 124

Query: 763 PGLGLDVPGFGGGPNNLSG---PSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHL 819
            G  +  PG G  P  + G   P  + GG       PG +G  PG  +G      APG +
Sbjct: 125 AGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPG-VGVLPGVPTGAGVKPKAPG-V 182

Query: 820 GGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGK-PGPTVIKVQNMPFTVSIDEILDFFYG 878
           GG  A  PG GP  GP P   G P G+   + K PG        +P+T      L + YG
Sbjct: 183 GGAFAGIPGVGPFGGPQP---GVPLGYPIKAPKLPGG-----YGLPYTTG---KLPYGYG 231

Query: 879 YQVIPGSVCLKYNEKGMPTG 898
               PG V     + G PTG
Sbjct: 232 ----PGGVAGAAGKAGYPTG 247



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 38/117 (32%), Positives = 48/117 (41%), Gaps = 23/117 (19%)

Query: 648 AVPGMPNA--GLPGVGLPSAGLPGAGLPSTGLPGSA---------ITSAGLPGAGMPSAG 696
           AVPG+      L GVG+P  G+ GAG  +      A         + +AGL G G+   G
Sbjct: 579 AVPGVLGGLGALGGVGIPG-GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLG 637

Query: 697 IPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPG 753
           +P  GG         +K A  G      G  GG+  F        LGG A   ARPG
Sbjct: 638 VPGVGGLGGIPPAAAAKAAKYGAA-GLGGVLGGAGQF-------PLGGVA---ARPG 683


>gi|126352322 elastin isoform c precursor [Homo sapiens]
          Length = 692

 Score = 95.1 bits (235), Expect = 3e-19
 Identities = 82/229 (35%), Positives = 103/229 (44%), Gaps = 47/229 (20%)

Query: 649 VPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFL 708
           VPG P  G   VG+P AG+PG G+P  G+P   +  AG+PGA +P    P A  +     
Sbjct: 328 VPGGPGFGPGVVGVPGAGVPGVGVPGAGIP--VVPGAGIPGAAVPGVVSPEAAAK----- 380

Query: 709 TVGSKEANNGPPFNFPG-NFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGL 767
              +K A  G     PG   GG       IP  G+G G F    PG   VG  G+PG+  
Sbjct: 381 -AAAKAAKYGAR---PGVGVGG-------IPTYGVGAGGF----PGF-GVGVGGIPGVA- 423

Query: 768 DVPGFGGGPNNLSGPSGFGGGPQ----------NFGNGPGSLGGPPGFGSGP-----PGL 812
            VPG GG P  + G  G G  P+           +G  PG +G  PG G  P     PG+
Sbjct: 424 GVPGVGGVP-GVGGVPGVGISPEAQAAAAAKAAKYGLVPG-VGVAPGVGVAPGVGVAPGV 481

Query: 813 GSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGPTVIKVQ 861
           G APG +G  P  G  PG G  PG     GP G A+++        K Q
Sbjct: 482 GLAPG-VGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAKVAAKAQ 525



 Score = 70.1 bits (170), Expect = 9e-12
 Identities = 80/271 (29%), Positives = 107/271 (39%), Gaps = 55/271 (20%)

Query: 632 PAQGKKGLKMPVPGNPAVPG--MPNAGLPGVGLPSA--------------------GLPG 669
           P  G  G+ +P  G P VPG  +P A +PGV  P A                    G+P 
Sbjct: 342 PGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPT 401

Query: 670 AGLPSTGLPGSAITSAGLPG-AGMPSAG-IPSAGGEEHAFLTVGSKEANNGPPFNFPGNF 727
            G+ + G PG  +   G+PG AG+P  G +P  GG     ++  ++ A       +    
Sbjct: 402 YGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVP 461

Query: 728 GGSNAFGPPIPPPGLGGGAFGDARPGM---PSVGNSGLPGLGLDVPGFGGG--------- 775
           G   A G  + P G+G        PG+   P VG +  PG+G+  PG G G         
Sbjct: 462 GVGVAPGVGVAP-GVGVAPGVGLAPGVGVAPGVGVA--PGVGV-APGIGPGGVAAAAKSA 517

Query: 776 -----PNNLSGPSGFGGGPQNFGNGPGSLG-----GPPGFG--SGPPGLGSAPGHLGGPP 823
                   L   +G G G    G G G  G     G PG G  +G PG G+ PG L    
Sbjct: 518 AKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAK 577

Query: 824 AFGPG---PGPGPGPGPIHIGGPPGFASSSG 851
           A   G   PG   G G +   G PG    +G
Sbjct: 578 AAKYGAAVPGVLGGLGALGGVGIPGGVVGAG 608



 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 67/213 (31%), Positives = 89/213 (41%), Gaps = 29/213 (13%)

Query: 645 GNPAVPGMPNAGLP--GVGLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGG 702
           G  A P +P A +P  G G+    +PG GLP    PG  +  A  PG G+   G+P+  G
Sbjct: 122 GVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGV-YPGGVLPGARFPGVGV-LPGVPTGAG 179

Query: 703 EEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGL 762
            +     VG   A  G P        G   FG P P   LG   +    P +P  G  GL
Sbjct: 180 VKPKAPGVGGAFA--GIP--------GVGPFGGPQPGVPLG---YPIKAPKLP--GGYGL 224

Query: 763 PGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPG-----FGSGPPGLGSAPG 817
           P     +P +G GP  ++G +G  G P   G GP +           FG+G  G+    G
Sbjct: 225 PYTTGKLP-YGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVG 283

Query: 818 HLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSS 850
             G P      PG  PG G I   G P  A+++
Sbjct: 284 GAGVPGV----PGAIPGIGGIAGVGTPAAAAAA 312



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 82/262 (31%), Positives = 109/262 (41%), Gaps = 40/262 (15%)

Query: 646 NPAVPGMPNAGLPGVGLPSAGL-PGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEE 704
           +P+ PG     +PG G+P     PGAGL + G  G A+   G P   +P  G+  AG   
Sbjct: 22  HPSRPGGVPGAIPG-GVPGGVFYPGAGLGALG--GGALGPGGKPLKPVP-GGLAGAG--- 74

Query: 705 HAFLTVGSKEANNGPPFNFPGNFG-GSNAFGPPIPPPGLGGGAFGDARPGMPSVGNS--- 760
                +G+  A   P    PG     + A+       GLGG       PG+  +G S   
Sbjct: 75  -LGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGG------VPGVGGLGVSAAP 127

Query: 761 GLPGLGLDVPGFGGGPNNLSG---PSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPG 817
            +PG  +  PG G  P  + G   P  + GG       PG +G  PG  +G      APG
Sbjct: 128 SVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPG-VGVLPGVPTGAGVKPKAPG 186

Query: 818 HLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGK-PGPTVIKVQNMPFTVSIDEILDFF 876
            +GG  A  PG GP  GP P   G P G+   + K PG        +P+T      L + 
Sbjct: 187 -VGGAFAGIPGVGPFGGPQP---GVPLGYPIKAPKLPGG-----YGLPYTTG---KLPYG 234

Query: 877 YGYQVIPGSVCLKYNEKGMPTG 898
           YG    PG V     + G PTG
Sbjct: 235 YG----PGGVAGAAGKAGYPTG 252



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 56/177 (31%), Positives = 70/177 (39%), Gaps = 46/177 (25%)

Query: 665 AGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFP 724
           AG+PG G+   G+PG  +  AG+PG G+  AG+P  G    A     +K A  G     P
Sbjct: 534 AGIPGLGV-GVGVPGLGV-GAGVPGLGV-GAGVPGFGAVPGAL--AAAKAAKYGAAV--P 586

Query: 725 GNFGGSNAFGPPIPPPGLGG-------------------GAFGDARPGMPSVGNSGLPGL 765
           G  GG  A G    P G+ G                   G  G A  G   VG  G+PG+
Sbjct: 587 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV 646

Query: 766 GLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGP--PG---LGSAPG 817
           G    G GG P   +  +   G           +   PGFG  P  PG   LG A G
Sbjct: 647 G----GLGGIPPAAAAKAAKYG-----------VAARPGFGLSPIFPGGACLGKACG 688



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 31/102 (30%), Positives = 40/102 (39%), Gaps = 16/102 (15%)

Query: 648 AVPGMPNA--GLPGVGLPSAGLPGAGLPSTGLPGSA---------ITSAGLPGAGMPSAG 696
           AVPG+      L GVG+P  G+ GAG  +      A         + +AGL G G+   G
Sbjct: 584 AVPGVLGGLGALGGVGIPG-GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLG 642

Query: 697 IPSAGGEEHAFLTVGSKEANNG----PPFNFPGNFGGSNAFG 734
           +P  GG         +K A  G    P F     F G    G
Sbjct: 643 VPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLG 684


>gi|126352700 elastin isoform b precursor [Homo sapiens]
          Length = 677

 Score = 95.1 bits (235), Expect = 3e-19
 Identities = 82/229 (35%), Positives = 103/229 (44%), Gaps = 47/229 (20%)

Query: 649 VPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFL 708
           VPG P  G   VG+P AG+PG G+P  G+P   +  AG+PGA +P    P A  +     
Sbjct: 313 VPGGPGFGPGVVGVPGAGVPGVGVPGAGIP--VVPGAGIPGAAVPGVVSPEAAAK----- 365

Query: 709 TVGSKEANNGPPFNFPG-NFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGL 767
              +K A  G     PG   GG       IP  G+G G F    PG   VG  G+PG+  
Sbjct: 366 -AAAKAAKYGAR---PGVGVGG-------IPTYGVGAGGF----PGF-GVGVGGIPGVA- 408

Query: 768 DVPGFGGGPNNLSGPSGFGGGPQ----------NFGNGPGSLGGPPGFGSGP-----PGL 812
            VPG GG P  + G  G G  P+           +G  PG +G  PG G  P     PG+
Sbjct: 409 GVPGVGGVP-GVGGVPGVGISPEAQAAAAAKAAKYGLVPG-VGVAPGVGVAPGVGVAPGV 466

Query: 813 GSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGPTVIKVQ 861
           G APG +G  P  G  PG G  PG     GP G A+++        K Q
Sbjct: 467 GLAPG-VGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAKVAAKAQ 510



 Score = 70.1 bits (170), Expect = 9e-12
 Identities = 80/271 (29%), Positives = 107/271 (39%), Gaps = 55/271 (20%)

Query: 632 PAQGKKGLKMPVPGNPAVPG--MPNAGLPGVGLPSA--------------------GLPG 669
           P  G  G+ +P  G P VPG  +P A +PGV  P A                    G+P 
Sbjct: 327 PGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPT 386

Query: 670 AGLPSTGLPGSAITSAGLPG-AGMPSAG-IPSAGGEEHAFLTVGSKEANNGPPFNFPGNF 727
            G+ + G PG  +   G+PG AG+P  G +P  GG     ++  ++ A       +    
Sbjct: 387 YGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVP 446

Query: 728 GGSNAFGPPIPPPGLGGGAFGDARPGM---PSVGNSGLPGLGLDVPGFGGG--------- 775
           G   A G  + P G+G        PG+   P VG +  PG+G+  PG G G         
Sbjct: 447 GVGVAPGVGVAP-GVGVAPGVGLAPGVGVAPGVGVA--PGVGV-APGIGPGGVAAAAKSA 502

Query: 776 -----PNNLSGPSGFGGGPQNFGNGPGSLG-----GPPGFG--SGPPGLGSAPGHLGGPP 823
                   L   +G G G    G G G  G     G PG G  +G PG G+ PG L    
Sbjct: 503 AKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAK 562

Query: 824 AFGPG---PGPGPGPGPIHIGGPPGFASSSG 851
           A   G   PG   G G +   G PG    +G
Sbjct: 563 AAKYGAAVPGVLGGLGALGGVGIPGGVVGAG 593



 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 70/223 (31%), Positives = 88/223 (39%), Gaps = 51/223 (22%)

Query: 638 GLKMPVPGNPAVPG-MPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGL----PGAGM 692
           G  +P PG    PG +P  GLPGV  P   LPGA  P  G+     T AG+    PG G 
Sbjct: 116 GAVVPQPGAGVKPGKVPGVGLPGV-YPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 174

Query: 693 PSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAFGDARP 752
             AGIP  G                         FGG        P PG+  G +    P
Sbjct: 175 AFAGIPGVGP------------------------FGG--------PQPGVPLG-YPIKAP 201

Query: 753 GMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPG-----FGS 807
            +P  G  GLP     +P +G GP  ++G +G  G P   G GP +           FG+
Sbjct: 202 KLP--GGYGLPYTTGKLP-YGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGA 258

Query: 808 GPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSS 850
           G  G+    G  G P      PG  PG G I   G P  A+++
Sbjct: 259 GAAGVLPGVGGAGVPGV----PGAIPGIGGIAGVGTPAAAAAA 297



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 73/247 (29%), Positives = 91/247 (36%), Gaps = 46/247 (18%)

Query: 632 PAQGKKGLKM-PVPGNPAVPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPGA 690
           PA G  G  + PVPG     G+  AGL G GL     P    P   +PG    +A    A
Sbjct: 44  PALGPGGKPLKPVPG-----GLAGAGL-GAGL--GAFPAVTFPGALVPGGVADAAAAYKA 95

Query: 691 GMPSAGIPSAGGEEHAFLTVGSKEANNG--------PPFNFPGNFGGSNAFGPPIPP--- 739
               AG+    G     ++ G+     G        P    PG + G    G   P    
Sbjct: 96  AKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGV 155

Query: 740 -PGLGGGAFGDARPGMPSVGN--SGLPGLGLDVPGFGGGPNNLSG--------PSGFG-- 786
            PG+  GA    +P  P VG   +G+PG+G   P  G  P    G        P G+G  
Sbjct: 156 LPGVPTGA--GVKPKAPGVGGAFAGIPGVG---PFGGPQPGVPLGYPIKAPKLPGGYGLP 210

Query: 787 --GGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPA-----FGPG-PGPGPGPGPI 838
              G   +G GPG + G  G    P G G  P       A     FG G  G  PG G  
Sbjct: 211 YTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA 270

Query: 839 HIGGPPG 845
            + G PG
Sbjct: 271 GVPGVPG 277



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 56/177 (31%), Positives = 70/177 (39%), Gaps = 46/177 (25%)

Query: 665 AGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFP 724
           AG+PG G+   G+PG  +  AG+PG G+  AG+P  G    A     +K A  G     P
Sbjct: 519 AGIPGLGV-GVGVPGLGV-GAGVPGLGV-GAGVPGFGAVPGAL--AAAKAAKYGAAV--P 571

Query: 725 GNFGGSNAFGPPIPPPGLGG-------------------GAFGDARPGMPSVGNSGLPGL 765
           G  GG  A G    P G+ G                   G  G A  G   VG  G+PG+
Sbjct: 572 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV 631

Query: 766 GLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGP--PG---LGSAPG 817
           G    G GG P   +  +   G           +   PGFG  P  PG   LG A G
Sbjct: 632 G----GLGGIPPAAAAKAAKYG-----------VAARPGFGLSPIFPGGACLGKACG 673



 Score = 34.3 bits (77), Expect = 0.55
 Identities = 42/131 (32%), Positives = 47/131 (35%), Gaps = 24/131 (18%)

Query: 735 PPIPPPGLGGGAFGDA-----RPGMPSVGNSGLPGLGLDVPGFGGGPN----NLSGPSGF 785
           P   P G+ GG F  A     +P  P  G  GL G GL   G G  P         P G 
Sbjct: 30  PGAIPGGVPGGVFYPALGPGGKPLKPVPG--GLAGAGLGA-GLGAFPAVTFPGALVPGGV 86

Query: 786 GGGPQNF--GNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGP 843
                 +        LGG PG G    GLG + G      A  P PG G  PG +   G 
Sbjct: 87  ADAAAAYKAAKAGAGLGGVPGVG----GLGVSAG------AVVPQPGAGVKPGKVPGVGL 136

Query: 844 PGFASSSGKPG 854
           PG       PG
Sbjct: 137 PGVYPGGVLPG 147



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 31/102 (30%), Positives = 40/102 (39%), Gaps = 16/102 (15%)

Query: 648 AVPGMPNA--GLPGVGLPSAGLPGAGLPSTGLPGSA---------ITSAGLPGAGMPSAG 696
           AVPG+      L GVG+P  G+ GAG  +      A         + +AGL G G+   G
Sbjct: 569 AVPGVLGGLGALGGVGIPG-GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLG 627

Query: 697 IPSAGGEEHAFLTVGSKEANNG----PPFNFPGNFGGSNAFG 734
           +P  GG         +K A  G    P F     F G    G
Sbjct: 628 VPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLG 669


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score = 95.1 bits (235), Expect = 3e-19
 Identities = 103/285 (36%), Positives = 120/285 (42%), Gaps = 66/285 (23%)

Query: 631  PPAQGKKGLK-----MPVPGNPAVPGMP-NAGLPGV-GLPS----AGLPGAGLP------ 673
            P   G  GLK     +  PG+P +PG   + GLPG+ G+P     AGLPG   P      
Sbjct: 1090 PGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQ 1149

Query: 674  -----STGLPGSAITSA--GLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGN 726
                 S G+PGSA      GLPG G P  G P A G++ +   VG       P    PG+
Sbjct: 1150 KGEPGSDGIPGSAGEKGEPGLPGRGFP--GFPGAKGDKGSKGEVGFPGLAGSP--GIPGS 1205

Query: 727  FGGSNAFGPPIPP--PGLGG-------GAFGD----ARPGMPSV-GNSGLPGL-GLDV-- 769
             G     GPP P   PGL G       G  GD     +PG+P + G  G PGL G+D   
Sbjct: 1206 KGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVK 1265

Query: 770  -----PGFGGGPNNLSGPSGFGG--GPQNFGNGPGSLG-----GPPGFGS-----GPPGL 812
                 PG+ G P  + GP G  G  G    G  PG  G     GPPG        G PGL
Sbjct: 1266 GDKGNPGWPGAPG-VPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGL 1324

Query: 813  GSAPGHLG--GPPAFGPGPGPGPGPGPIHI-GGPPGFASSSGKPG 854
                G  G  G P     PGP   PGP  I  G PG     G PG
Sbjct: 1325 QGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPG 1369



 Score = 90.9 bits (224), Expect = 5e-18
 Identities = 92/234 (39%), Positives = 101/234 (43%), Gaps = 32/234 (13%)

Query: 635 GKKGLKMPVPGNPAVPGMPNA-GLPGVGLPSAGLPGA-GLP-STGLPGSAITSAGLPGA- 690
           G KG +   PG P  PG+P   G PG  +P  G PGA GLP S G PG      G PG  
Sbjct: 615 GDKG-QAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQ-GDRGFPGTP 672

Query: 691 GMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPP--IPPPGLGGGAFG 748
           G P  G+P            G K A   P   FPG  G     G P  + PPG  G    
Sbjct: 673 GRP--GLP------------GEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGF 718

Query: 749 DARPGMPSV-GNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGS 807
           +  PG P V G  G PG+GL  PG  G P    G  G  G P   G+  G  G P   G+
Sbjct: 719 NGLPGNPGVQGQKGEPGVGL--PGLKGLP----GLPGIPGTPGEKGS-IGVPGVPGEHGA 771

Query: 808 -GPPGLGSAPGHLGGPPAFGPGPGPG-PGPGPIHIGGPPGFASSSGKPGPTVIK 859
            GPPGL    G  G P   G    PG PG GP    GPPG     G  GP  IK
Sbjct: 772 IGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIK 825



 Score = 90.9 bits (224), Expect = 5e-18
 Identities = 88/238 (36%), Positives = 103/238 (43%), Gaps = 27/238 (11%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSA--GLPGA-GLPSTGLPGSAITSAGL 687
           P  +G+ G  +P+PG P   G+P  G PG   P    G PG  G P  GLPG    + G 
Sbjct: 632 PGPKGEPGKIVPLPGPPGAEGLP--GSPGFPGPQGDRGFPGTPGRP--GLPGEK-GAVGQ 686

Query: 688 PGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFN-FPGNFGGSNAFGPP-IPPPGLGGG 745
           PG G P  G P   G +     +G       P FN  PGN G     G P +  PGL G 
Sbjct: 687 PGIGFP--GPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGL 744

Query: 746 AFGDARPGMPSV-GNSGLPGLGLDVPGFGG--GPNNLSGPSGFGGGPQNFGNGPGSLGGP 802
                 PG P   G+ G+PG    VPG  G  GP  L G  G  G P      PGS+G P
Sbjct: 745 PGLPGIPGTPGEKGSIGVPG----VPGEHGAIGPPGLQGIRGEPGPP----GLPGSVGSP 796

Query: 803 PGFGSGPPGLGSAPGHLGGPPAFGP----GPGPGPGPGPIHIGGPPGFASSSGKPGPT 856
              G GPPG    PG  G P   GP    G    PG   + + GP G   + G PG T
Sbjct: 797 GVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGIT 854



 Score = 90.5 bits (223), Expect = 7e-18
 Identities = 93/279 (33%), Positives = 108/279 (38%), Gaps = 65/279 (23%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPN----AGLPGVGLPSA-------GLPG-AGLPST--- 675
           P  QG +G     PG P  PG+P      G PG+G P         GLPG  G P T   
Sbjct: 660 PGPQGDRGF----PGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGR 715

Query: 676 ----GLPGSAITSA--GLPGAGMP-------------------SAGIPSAGGEEHAFLTV 710
               GLPG+       G PG G+P                   S G+P   GE  A    
Sbjct: 716 PGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPP 775

Query: 711 GSKEANNGP-PFNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGM---PSV-GNSGLPGL 765
           G +     P P   PG+ G      P I PPG  G   G   PG+   P + G  G PG 
Sbjct: 776 GLQGIRGEPGPPGLPGSVGSPGV--PGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGF 833

Query: 766 -GLDVPGFGG--GPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLG-- 820
            GLD+PG  G  G   L G +G  G P      PG  G P     G PG   + G +G  
Sbjct: 834 PGLDMPGPKGDKGAQGLPGITGQSGLP----GLPGQQGAP-----GIPGFPGSKGEMGVM 884

Query: 821 GPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGPTVIK 859
           G P     PGP   PG     G  GF  SSG  G   +K
Sbjct: 885 GTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLK 923



 Score = 87.0 bits (214), Expect = 7e-17
 Identities = 87/249 (34%), Positives = 102/249 (40%), Gaps = 37/249 (14%)

Query: 631  PPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSA----GLPGAGLP--STGLPGSAITS 684
            P  +G  G+    PG P +PG P   + G+GLP      G+PG   P  S GLPG     
Sbjct: 989  PGPKGDPGIS-GTPGAPGLPG-PKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAK 1046

Query: 685  AGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPP--PGL 742
                 AG P  GIP   GE+      G +     P    PG  G   + G P  P  PGL
Sbjct: 1047 GEKGQAGPPGIGIPGLRGEK------GDQGIAGFP--GSPGEKGEKGSIGIPGMPGSPGL 1098

Query: 743  GGGAFGDARPGMPSV----GNSGLPGLGLDVPGFGG-----GPNNLSGPSGFGGGPQNFG 793
             G       PG P +    G+ GLPGL   +PG  G     G    +GP+G  G P + G
Sbjct: 1099 KGSPGSVGYPGSPGLPGEKGDKGLPGLD-GIPGVKGEAGLPGTPGPTGPAGQKGEPGSDG 1157

Query: 794  NGPGSLG--GPPGF-GSGPPGLGSAPGHLG-----GPPAFGPGPGPGPGPGPIHIGGPPG 845
              PGS G  G PG  G G PG   A G  G     G P     PG     G     GPPG
Sbjct: 1158 I-PGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPG 1216

Query: 846  FASSSGKPG 854
                 G PG
Sbjct: 1217 PQGQPGLPG 1225



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 91/265 (34%), Positives = 110/265 (41%), Gaps = 44/265 (16%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPNA-GLPG-VGLPSA-GLPGAGLPSTGLPGSAITSAGL 687
           P A+G +GL    PG   V G+P   G PG +G P A G PG       L G      G 
Sbjct: 494 PGAKGDRGL----PGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDK-GDPGF 548

Query: 688 PG-------AGMPSA-GIPSAGGEEHAFLTVGSKEANNGPP--FNFPGNFGGSNAFGPP- 736
           PG       AG P   G P   G + +  +VG K    GPP    FPG+ G +   GPP 
Sbjct: 549 PGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLK-GERGPPGGVGFPGSRGDTGPPGPPG 607

Query: 737 ------IPPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGG--G 788
                 I   G  G   G   PG+P  G  G PG  + +PG   G   L G  GF G  G
Sbjct: 608 YGPAGPIGDKGQAGFPGGPGSPGLP--GPKGEPGKIVPLPG-PPGAEGLPGSPGFPGPQG 664

Query: 789 PQNFGNGPGSLG--------GPPGFG-SGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIH 839
            + F   PG  G        G PG G  GPPG     G  G P   GP PG    PG   
Sbjct: 665 DRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPG---PKGVDGLPGDMGP-PGTPGRPGFNG 720

Query: 840 IGGPPGFASSSGKPGPTVIKVQNMP 864
           + G PG     G+PG  +  ++ +P
Sbjct: 721 LPGNPGVQGQKGEPGVGLPGLKGLP 745



 Score = 74.3 bits (181), Expect = 5e-13
 Identities = 90/270 (33%), Positives = 103/270 (38%), Gaps = 50/270 (18%)

Query: 631 PPAQGKKGLKMP-----VPGNPAVPGMPNA-GLPGVGLPSAGLPGAG--------LPSTG 676
           P   G KG + P      PGNP +PG+P   G PG      G+PG          L   G
Sbjct: 84  PGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPG----PPGIPGCNGTKGERGPLGPPG 139

Query: 677 LPGSAITSAGLPGA-GMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFG--GSNAF 733
           LPG A    G PG  G+P  G+    GE    +     +   G P   PG  G  G    
Sbjct: 140 LPGFA----GNPGPPGLP--GMKGDPGEILGHVPGMLLKGERGFP-GIPGTPGPPGLPGL 192

Query: 734 GPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFG 793
             P+ PPG  G       PG P  G  G  GL    P    G   +SGP G  G  Q   
Sbjct: 193 QGPVGPPGFTGPPGPPGPPGPP--GEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQE 250

Query: 794 NGP----GSLG--GPPGFGSGPPGLGSA-----PGHLGGPPAFG-------PG-PGPGPG 834
            G     G  G  G PGF  G PG+G       PG  G P   G       PG PG    
Sbjct: 251 KGDFATKGEKGQKGEPGF-QGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGY 309

Query: 835 PGPIHIGGPPGFASSSGKPGPTVIKVQNMP 864
           PG I   GP G    +G PGP  I +   P
Sbjct: 310 PGLIGRQGPQGEKGEAGPPGPPGIVIGTGP 339



 Score = 71.2 bits (173), Expect = 4e-12
 Identities = 96/291 (32%), Positives = 113/291 (38%), Gaps = 82/291 (28%)

Query: 635 GKKGLKMPVPGNPAVPGMPNA-GLPGVGLPSA--GLPG----AGLPSTGLPGSAITSAGL 687
           G KG K    G   +PG+    G PG+  P    G PG     G P  GLPG+  T  G 
Sbjct: 43  GVKGQK----GERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEP--GLPGTKGTR-GP 95

Query: 688 PGA-GMP-SAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGG 745
           PGA G P + G+P   G++             GPP   PG  G     GP + PPGL G 
Sbjct: 96  PGASGYPGNPGLPGIPGQD----------GPPGPP-GIPGCNGTKGERGP-LGPPGLPGF 143

Query: 746 AFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSG--PSGFGGGPQNFGNGPGSLGGPP 803
           A           GN G PGL    PG  G P  + G  P     G + F   PG  G P 
Sbjct: 144 A-----------GNPGPPGL----PGMKGDPGEILGHVPGMLLKGERGF---PGIPGTP- 184

Query: 804 GFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGP--------IHIGGPPGFASSSGKPGP 855
               GPPGL    G + GPP F   PGP   PGP        +   GP G     G  GP
Sbjct: 185 ----GPPGLPGLQGPV-GPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGP 239

Query: 856 TVIKVQNMPFTVSIDEILDFFY----------GYQVIPGSVCLKYNEKGMP 896
                  +P    + E  DF            G+Q +PG       EKG P
Sbjct: 240 -----PGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPG-----VGEKGEP 280



 Score = 70.1 bits (170), Expect = 9e-12
 Identities = 99/295 (33%), Positives = 107/295 (36%), Gaps = 82/295 (27%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPNAGLPG-VGLPSAGLPGA-------GLPSTGLPGSAI 682
           P  +G+ G K   PG P  PG P   +PG  G P  G PG        G P T LPG + 
Sbjct: 352 PGPRGEPGPK-GFPGLPGQPGPPGLPVPGQAGAP--GFPGERGEKGDRGFPGTSLPGPSG 408

Query: 683 TSAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFN-----------FPGNFG--- 728
              GLPG    S G P   G      T G  E   GPP +           F G  G   
Sbjct: 409 RD-GLPGPP-GSPGPPGQPG-----YTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKG 461

Query: 729 --GSNAF--------GPPIP--PPGLGG-----GAFGD----ARPGMPSV-GNSGLPGLG 766
             G +          GPP P  PPG  G     GA GD     R G+  V G  G PGL 
Sbjct: 462 QKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGL- 520

Query: 767 LDVPGFGGGPNNL---------SGPSGFGGGPQNFGNG-----------PGSLGGPPGFG 806
           +  PG  G P             G  GF G P   G             PG  G P   G
Sbjct: 521 IGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVG 580

Query: 807 ----SGPPGLGSAPGHLG--GPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGP 855
                GPPG    PG  G  GPP   PG GP    G     G PG   S G PGP
Sbjct: 581 LKGERGPPGGVGFPGSRGDTGPPG-PPGYGPAGPIGDKGQAGFPGGPGSPGLPGP 634



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 85/254 (33%), Positives = 93/254 (36%), Gaps = 50/254 (19%)

Query: 634 QGKKGLK--MPVPGNPAVPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPGAG 691
           QG KG K    V G P VPG       G    + G  G      G PG      G+PG G
Sbjct: 225 QGPKGDKGDQGVSGPPGVPGQAQVQEKG-DFATKGEKG----QKGEPGFQ----GMPGVG 275

Query: 692 MPSAGIPSAGGEEHAFLTVGSKEANNGPPF----NFPGNFG-----GSNAFGPPIPPPGL 742
               G P   G        G K     P F     +PG  G     G      P  PPG+
Sbjct: 276 --EKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGI 333

Query: 743 --GGGAFGD----ARPGMPSV----GNSGLPGL-------GLDVPGFGGGPN-----NLS 780
             G G  G+      PG P      G  G PGL       GL VPG  G P         
Sbjct: 334 VIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEK 393

Query: 781 GPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHI 840
           G  GF G      +G   L GPPG   GPPG    PG+  G     PGP PG   GP  I
Sbjct: 394 GDRGFPGTSLPGPSGRDGLPGPPG-SPGPPG---QPGYTNGIVECQPGP-PGD-QGPPGI 447

Query: 841 GGPPGFASSSGKPG 854
            G PGF    G+ G
Sbjct: 448 PGQPGFIGEIGEKG 461



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 81/269 (30%), Positives = 101/269 (37%), Gaps = 52/269 (19%)

Query: 633  AQGKKGLKMPVPGNPAVPGMPNA----GLPGVGLPSAGLPGAGLPSTGLPGSAITSA--- 685
            A G  GL+  + G P  PG+P +    G+PG+G P A  P  G    GL G         
Sbjct: 771  AIGPPGLQ-GIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKG 829

Query: 686  --GLPGAGMP-------SAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPP 736
              G PG  MP       + G+P   G+       G + A   P   FPG+ G     G P
Sbjct: 830  FPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIP--GFPGSKGEMGVMGTP 887

Query: 737  IPP--------PGLGGGAFGDARPGMPSVGNSGLPGLGLD-----VPGFGGGPN-----N 778
              P        PGL G       PG  S G  G PGL  D     +PG  G  +     +
Sbjct: 888  GQPGSPGPVGAPGLPGEKGDHGFPG--SSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGS 945

Query: 779  LSGPSGFGG--------GPQNFGNGPGSLGGPPGFGS----GPPGLGSAPGHLGGPPAFG 826
            + G  G  G        G +     PG+ G P   G     G PG    PG + G P   
Sbjct: 946  MKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPG-ISGTPGAP 1004

Query: 827  PGPGPGPGPGPIHIGGPPGFASSSGKPGP 855
              PGP    G + + G PG     G PGP
Sbjct: 1005 GLPGPKGSVGGMGLPGTPGEKGVPGIPGP 1033



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 80/229 (34%), Positives = 94/229 (41%), Gaps = 32/229 (13%)

Query: 634 QGKKGLKMPVPGNPAVPGMPNAGLPG-VGLPSAGLPGAGLPSTGLPGSAITSAGLPGA-G 691
           +G+  L   + G    PG    G PG +G P  G PGA     GLPG     AG+PG  G
Sbjct: 463 KGESCLICDIDGYRGPPGPQ--GPPGEIGFP--GQPGAK-GDRGLPGRDGV-AGVPGPQG 516

Query: 692 MPSA-GIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAFGDA 750
            P   G P A GE   F      + + G P  FPG  G +   G P            D 
Sbjct: 517 TPGLIGQPGAKGEPGEFYFDLRLKGDKGDP-GFPGQPGMTGRAGSP----------GRDG 565

Query: 751 RPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFG--GGPQNFGNGP-GSLG--GPPGF 805
            PG+P  G  G PG  + + G  G P  +  P   G  G P   G GP G +G  G  GF
Sbjct: 566 HPGLP--GPKGSPG-SVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGF 622

Query: 806 GSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPG 854
             GP G    PG  G P    P PGP   PG   + G PGF    G  G
Sbjct: 623 PGGP-GSPGLPGPKGEPGKIVPLPGP---PGAEGLPGSPGFPGPQGDRG 667



 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 75/214 (35%), Positives = 87/214 (40%), Gaps = 35/214 (16%)

Query: 631  PPAQGKKGLKMPVPGNPAVPGMPNAGLPGV-GLPS-AGLPGAGLPSTGLPGSA--ITSAG 686
            P   G KG K    GNP  PG P  G+PG  G P   G+PG G  S G+ GS   +   G
Sbjct: 1259 PGIDGVKGDK----GNPGWPGAP--GVPGPKGDPGFQGMPGIG-GSPGITGSKGDMGPPG 1311

Query: 687  LPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGA 746
            +PG   P  G+P   G       +   + + G P       G     GPP PP   G   
Sbjct: 1312 VPGFQGPK-GLPGLQG-------IKGDQGDQGVP-------GAKGLPGPPGPP---GPYD 1353

Query: 747  FGDARPGMPSV-GNSGLPGL-GLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLG--GP 802
                 PG+P   G  GL GL GL  P    G   L G  G  G P  F   PG  G  GP
Sbjct: 1354 IIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIP-GFDGAPGQKGEMGP 1412

Query: 803  PGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPG 836
             G  +GP G    PG  G P + GP   P    G
Sbjct: 1413 AG-PTGPRGFPGPPGPDGLPGSMGPPGTPSVDHG 1445



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 35/139 (25%), Positives = 43/139 (30%), Gaps = 20/139 (14%)

Query: 99  PANASRSGPPPSSGMSSRVNLPTTVSNFNNPSPSVVTATTSVHESNKNIQTFSTASVGTA 158
           P      GPP +SG      LP        P P  +            +           
Sbjct: 87  PGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPL----------G 136

Query: 159 PPNMGASFGSPTFSSTVPSTASPMNTVPPPP---------IPPIPAMPSLPPMPSIPPIP 209
           PP +    G+P           P   +   P          P IP  P  P +P +   P
Sbjct: 137 PPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQG-P 195

Query: 210 VPPPVPTLPPVPPVPPIPP 228
           V PP  T PP PP PP PP
Sbjct: 196 VGPPGFTGPPGPPGPPGPP 214



 Score = 34.3 bits (77), Expect = 0.55
 Identities = 39/168 (23%), Positives = 49/168 (29%), Gaps = 21/168 (12%)

Query: 106 GPPPSSGMSSRVNLPTTVSNFNNPSPSVVTATTSVHESNKNIQTFSTASVGTAPPNMGAS 165
           GPP   G +    LP T      P         S +  N  +           PP +   
Sbjct: 73  GPPGQKGDTGEPGLPGTKGTRGPPG-------ASGYPGNPGLPGIPGQDGPPGPPGIPGC 125

Query: 166 FGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVP----PPVPTLPPVP 221
            G          T      + PP +P     P  P +P +   P       P   L    
Sbjct: 126 NG----------TKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGER 175

Query: 222 PVPPIPPVPSVPPMTPLPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLN 269
             P IP  P  P +  L    G P    PP  P P G  G    M L+
Sbjct: 176 GFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLS 223



 Score = 31.6 bits (70), Expect = 3.6
 Identities = 40/156 (25%), Positives = 49/156 (31%), Gaps = 37/156 (23%)

Query: 159 PPNMGASFGSPTFSSTVPSTASPMNTVPP--PPIPPIPAMPSLPPMPSIPPI-------- 208
           PP      G P    T  +   P  +  P  P +P IP     P  P IP          
Sbjct: 74  PPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERG 133

Query: 209 PVPPP-VPTLPPVPPVPPIPPVPSVP---------------------PMTPLPPMSGMPP 246
           P+ PP +P     P  P +P +   P                     P TP PP  G+P 
Sbjct: 134 PLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPP--GLPG 191

Query: 247 LNPPPVAPL---PAGMNGSGAPMNLNNNLNPMFLGP 279
           L  P   P    P G  G   P      +   F GP
Sbjct: 192 LQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGP 227



 Score = 31.6 bits (70), Expect = 3.6
 Identities = 30/114 (26%), Positives = 35/114 (30%), Gaps = 8/114 (7%)

Query: 156 GTAPPNMGASFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVP 215
           G  P       G   F     S   P     P  I P+P  P    +P  P  P P    
Sbjct: 607 GYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDR 666

Query: 216 TLPPVPPVPPIPPVPSVPPMT----PLPP----MSGMPPLNPPPVAPLPAGMNG 261
             P  P  P +P             P PP    + G+P    PP  P   G NG
Sbjct: 667 GFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNG 720



 Score = 31.2 bits (69), Expect = 4.7
 Identities = 26/78 (33%), Positives = 28/78 (35%), Gaps = 16/78 (20%)

Query: 200 PPMPSIPPIPVPPPVPTLP--PVPPVPPIPPVPSVP--------------PMTPLPPMSG 243
           P  P     P P   P LP  P PP  P+P     P              P T LP  SG
Sbjct: 349 PGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSG 408

Query: 244 MPPLNPPPVAPLPAGMNG 261
              L  PP +P P G  G
Sbjct: 409 RDGLPGPPGSPGPPGQPG 426



 Score = 31.2 bits (69), Expect = 4.7
 Identities = 29/115 (25%), Positives = 38/115 (33%), Gaps = 26/115 (22%)

Query: 172  SSTVPSTASPMNTVPPPPIPPIPAMPSLPP--------------MPSIPPIPVPPPVPTL 217
            S  +P +      + PP     P +P  P                P +P +P P   P L
Sbjct: 1199 SPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGL 1258

Query: 218  PPVPPV------PPIPPVPSVPPMTPLPPMSGMPPLNPPPVAPLPAGMNGSGAPM 266
            P +  V      P  P  P VP     P   GMP +   P      G+ GS   M
Sbjct: 1259 PGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSP------GITGSKGDM 1307


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 93.6 bits (231), Expect = 8e-19
 Identities = 95/271 (35%), Positives = 100/271 (36%), Gaps = 51/271 (18%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPNA----GLPGV-GLPSA-------GLPGAGLPSTGLP 678
           PP +G K     VPG    PG+       G PG  G P A       GLPG   P T  P
Sbjct: 673 PPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGT--PGTDGP 730

Query: 679 GSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSK----EANNGPPFNFPGNFGGSNAFG 734
             A   AG PGA  P  G+    GE  A    G K    +     P   PG  GG    G
Sbjct: 731 KGASGPAGPPGAQGPP-GLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTG 789

Query: 735 PPIPPPGLGG--GAFGDARPGMP--SVGNSGLPG----LGLDVPGFGGGPNNLSGPSGFG 786
           P I PPG  G  G  G+  P  P  S G  G PG     G   P    GP    G  G  
Sbjct: 790 P-IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 848

Query: 787 G--------------GPQNFGNGPGSLG-----GPPGF--GSGPPGLGSAPGHLG--GPP 823
           G              GPQ     PG  G     GP G     GPPG    PG  G  GPP
Sbjct: 849 GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP 908

Query: 824 AFGPGPGPGPGPGPIHIGGPPGFASSSGKPG 854
                PGP   PGP    GP G    SG PG
Sbjct: 909 GSNGNPGPPGPPGPSGKDGPKGARGDSGPPG 939



 Score = 80.1 bits (196), Expect = 9e-15
 Identities = 91/263 (34%), Positives = 101/263 (38%), Gaps = 47/263 (17%)

Query: 630 NPPAQGKKGLKMPVP--GNPAVPGMPN----AGLPGVGLPSAGLPGA----GLPST-GLP 678
           NP   G+ G+  P+   G P  PG P     AG PG      G PG     G P T GLP
Sbjct: 226 NPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKA-GERGPPGPQGARGFPGTPGLP 284

Query: 679 GSAITSAGLPG--AGMPSAGIPSAGGEEHAFLTVGSKEANNGP----PFNFPGNFGGSNA 732
           G      G PG       AG P   GE       GS   N  P    P   PG  G +  
Sbjct: 285 GVK-GHRGYPGLDGAKGEAGAPGVKGES------GSPGENGSPGPMGPRGLPGERGRTG- 336

Query: 733 FGPPIPPPGLGGGAFGDARPGMPS----VGNSGLPGLGLDVPGFGG--GPNNLSGPSGFG 786
                 P G  G    D +PG       VG +G PG     PG  G  GP    GP G  
Sbjct: 337 ------PAGAAGARGNDGQPGPAGPPGPVGPAGGPGFP-GAPGAKGEAGPTGARGPEG-A 388

Query: 787 GGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFG----PG-PGPGPGPGPIHIG 841
            GP+     PGS G  P   SG PG    PG  G   A G    PG PGP   PGP    
Sbjct: 389 QGPRGEPGTPGSPG--PAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 446

Query: 842 GPPGFASSSGKPGPTVIKVQNMP 864
           GP G    +G+PG    K +  P
Sbjct: 447 GPLGPKGQTGEPGIAGFKGEQGP 469



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 92/253 (36%), Positives = 101/253 (39%), Gaps = 52/253 (20%)

Query: 634 QGKKGLKMPVPGNPAVPGMPNA----GLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPG 689
           QGK G     PG    PG P      G PGV     G PG    + G PG A    GLPG
Sbjct: 572 QGKVG-PSGAPGEDGRPGPPGPQGARGQPGV----MGFPGPK-GANGEPGKA-GEKGLPG 624

Query: 690 A-GMPSAGIPSAGGEEHAFLTVG-SKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAF 747
           A G+   G+P   GE  A    G +  A        PG  G     GPP  PPG GG   
Sbjct: 625 APGL--RGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP-GPPGEGG--- 678

Query: 748 GDARPGMPSV-GNSGLPGL-----GLDVPGFGGGPN--NLSGPSGFGGGPQNFG-NGPGS 798
              +PG   V G +G PGL         PG  G P    L GP G  G P   G  G   
Sbjct: 679 ---KPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASG 735

Query: 799 LGGPPGFGSGPPGLGSAPGHLGGPPAFGP----------GPGPGPG-------PGPIHIG 841
             GPPG   GPPGL   PG  G     GP          GP   PG        GPI   
Sbjct: 736 PAGPPG-AQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI--- 791

Query: 842 GPPGFASSSGKPG 854
           GPPG A ++G+ G
Sbjct: 792 GPPGPAGANGEKG 804



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 98/288 (34%), Positives = 107/288 (37%), Gaps = 71/288 (24%)

Query: 633 AQGKKGLKMP--VPGNPAVPGMPNA-GLPGV-GLP----SAGLPG-AGLPS--------- 674
           A+G +G + P   PG P  PG   A G PG  G+P    SAG PG AG P          
Sbjct: 382 ARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPG 441

Query: 675 -------------TGLPGSAITSA-----GLPGAGMPSAGIPSAGGEEHAFLTVGSK--- 713
                        TG PG A         G PG   P  G P   GEE      G     
Sbjct: 442 PQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ-GAPGPAGEEGKRGARGEPGGV 500

Query: 714 -----EANNGPPFN--FPGNFGGSNAFGPPIP--PPGLGGGAFGDARPGMPSVGNSGLPG 764
                    G P N  FPG  G +   G P    P GL G    +  PG P  G  GLPG
Sbjct: 501 GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP--GEPGLPG 558

Query: 765 L-GLDVPGFGGGPNNLSGPSGFGG--------GPQNFGNGPGSLG--GPPGFG-----SG 808
             GL       GP    GPSG  G        GPQ     PG +G  GP G       +G
Sbjct: 559 ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG 618

Query: 809 PPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGPT 856
             GL  APG  G P   G     GP PGP    GP G     G PGP+
Sbjct: 619 EKGLPGAPGLRGLPGKDGETGAAGP-PGP---AGPAGERGEQGAPGPS 662



 Score = 74.3 bits (181), Expect = 5e-13
 Identities = 85/261 (32%), Positives = 95/261 (36%), Gaps = 40/261 (15%)

Query: 628 EKNPPAQGKKGLKMPVPGNPAVPGMPNA-GLPGVGLPSAG---------LPGAGLPSTGL 677
           EK  P    +  +   PGNP  PG P   G PG+G   A            GA L     
Sbjct: 142 EKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQG 201

Query: 678 PGSAITSAGLPG-AGMPSA----GIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNA 732
           P   +   G PG AG P      G P   GE      +G +    GPP   PG  G    
Sbjct: 202 PMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPR----GPP-GPPGKPGDDGE 256

Query: 733 FGPPIP-----PPGLGGGAFGDARPGMPSV-GNSGLPGLG-----LDVPGFGG-----GP 776
            G P       PPG  G       PG+P V G+ G PGL         PG  G     G 
Sbjct: 257 AGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGE 316

Query: 777 NNLSGPSGFGGGPQNFGN-GPGSLGGPPGFGSGPPGLGSAPGHLG--GPPAFGPGPGPGP 833
           N   GP G  G P   G  GP    G  G   G PG    PG +G  G P F   PG   
Sbjct: 317 NGSPGPMGPRGLPGERGRTGPAGAAGARG-NDGQPGPAGPPGPVGPAGGPGFPGAPGAKG 375

Query: 834 GPGPIHIGGPPGFASSSGKPG 854
             GP    GP G     G+PG
Sbjct: 376 EAGPTGARGPEGAQGPRGEPG 396



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 92/269 (34%), Positives = 101/269 (37%), Gaps = 61/269 (22%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPN-------AGLPGVGLPSA-----GLPGA----GLPS 674
           P   G+KGL    PG P + G+P        AG PG   P+      G PG     GLP 
Sbjct: 614 PGKAGEKGL----PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPG 669

Query: 675 TGLP---GSAITSAGLPG-AGMPSA-------GIPSAGGEEHAFLTVGSKEANNGPPFNF 723
              P   G      G+PG AG P         G P   G   A    G +    G P   
Sbjct: 670 PPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPR----GLP-GT 724

Query: 724 PGNFGGSNAFGPPIPP-----PGLGG-----GAFGDARP--GMPSVGNSGLPGLGLDVPG 771
           PG  G   A GP  PP     PGL G     GA G A P      VG  G  G     PG
Sbjct: 725 PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEG----APG 780

Query: 772 FGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLG-----GPPAFG 826
             GG   L+GP G   GP    NG     GPPG  +G  G   APG  G     GP  F 
Sbjct: 781 KDGG-RGLTGPIG-PPGPAG-ANGEKGEVGPPG-PAGSAGARGAPGERGETGPPGPAGFA 836

Query: 827 PGPGPGPGPGPIHIGGPPGFASSSGKPGP 855
             PG    PG     G  G    +G PGP
Sbjct: 837 GPPGADGQPGAKGEQGEAGQKGDAGAPGP 865



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 84/250 (33%), Positives = 91/250 (36%), Gaps = 36/250 (14%)

Query: 631  PPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSA-GLPGAGLPSTGLPGSAITSAGLPG 689
            P  QG  G   P P  P     P       G P A G PGA     G PGS   + G PG
Sbjct: 863  PGPQGPSGA--PGPQGPTGVTGPKGARGAQGPPGATGFPGAA-GRVGPPGSN-GNPGPPG 918

Query: 690  AGMPSA--GIPSAGGEEHAFLTVGSK--EANNGPPFNF--PGNFGGSNAFGPPIPPPGLG 743
               PS   G   A G+       G    +   GPP     PG+ G S A GPP  P GL 
Sbjct: 919  PPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPP-GPQGLA 977

Query: 744  GGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPP 803
            G       PG    G  G PGL    PG  G P     P   G        GP  L GP 
Sbjct: 978  GQRGIVGLPGQR--GERGFPGL----PGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA 1031

Query: 804  GF--------GSGPPGLGSAPG---------HLGGPPAFGPGPGPGPGPGPIHIGGPPGF 846
            G           GPPG   A G          +G P A GP   PGP  GP    G  G 
Sbjct: 1032 GEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPA-GPTGKQGDRGE 1090

Query: 847  ASSSGKPGPT 856
            A + G  GP+
Sbjct: 1091 AGAQGPMGPS 1100



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 83/259 (32%), Positives = 94/259 (36%), Gaps = 45/259 (17%)

Query: 621  LEDMREIEKNPPAQGKKGLKMPVPGNPAVPGMPNA-GLPGVGLPSAGLPG-AGLPSTGLP 678
            L   R I   P  +G++G     PG P   G P   G PG      G PG  G P    P
Sbjct: 976  LAGQRGIVGLPGQRGERGF----PGLPGPSGEPGKQGAPGAS-GDRGPPGPVGPPGLTGP 1030

Query: 679  GSAITSAGLPGAGMP-----SAGIPSAGGEEHAFLTVGSKEANNGP----PFNFPGNFGG 729
                   G PGA  P     +AG+    GE  A    G+      P    P    G+ G 
Sbjct: 1031 AGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGE 1090

Query: 730  SNAFGP--PIPPPGLGG-----GAFGD----ARPGMPSV-GNSGLPGL-GLDVPGFGGGP 776
            + A GP  P  P G  G     G  GD      PG   + G+ G  GL GL  P    G 
Sbjct: 1091 AGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGD 1150

Query: 777  NNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPG 836
               SGP+G           P    GPPG    P G     G  G P   GP PGP    G
Sbjct: 1151 QGASGPAG-----------PSGPRGPPG----PVGPSGKDGANGIPGPIGP-PGPRGRSG 1194

Query: 837  PIHIGGPPGFASSSGKPGP 855
                 GPPG     G PGP
Sbjct: 1195 ETGPAGPPGNPGPPGPPGP 1213



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 86/273 (31%), Positives = 98/273 (35%), Gaps = 50/273 (18%)

Query: 628  EKNPPAQ-GKKGLKMPV--PGNPAVPGMPN-AGLPGVGLPSAGLPGAGLPSTGLPGSAIT 683
            +  PP + G+ GL+ P   PG    PG    +G  G   P       G+   GLPG    
Sbjct: 934  DSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGI--VGLPGQR-G 990

Query: 684  SAGLPGAGMPSA-----GIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIP 738
              G PG   PS      G P A G+      VG        P   PG  G   A GPP  
Sbjct: 991  ERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTG--PAGEPGREGSPGADGPPGR 1048

Query: 739  PPGLG--------GGAFGDARPGMP-SVGNSGLPGLGLDVPGFGG-GPNNLSGPSGFGG- 787
                G        G       PG P S G +G  G   D    G  GP   SGP+G  G 
Sbjct: 1049 DGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI 1108

Query: 788  -GPQNFGNGPGSLGGPPGFG-------SGPPGLGSAPGHLGGPPAFGPG--------PGP 831
             GPQ      G  G P   G       +G  GL   PG  G   A GP         PGP
Sbjct: 1109 QGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGP 1168

Query: 832  -GPG--------PGPIHIGGPPGFASSSGKPGP 855
             GP         PGPI   GP G +  +G  GP
Sbjct: 1169 VGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP 1201



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 49/154 (31%), Positives = 54/154 (35%), Gaps = 44/154 (28%)

Query: 736 PIPPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGG--GPQNFG 793
           PI P  L   A    +PG    G  G PG   D+ G  G P    GP G  G  GP+   
Sbjct: 87  PICPTDL---ATASGQPGPK--GQKGEPGDIKDIVGPKGPP----GPQGPAGEQGPRGDR 137

Query: 794 NGPGSLGGP-PGFGSGPPGLGSAPGHLG-----GPPAFG--------------------- 826
              G  G P P    G PG    PG  G     GPP  G                     
Sbjct: 138 GDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLG 197

Query: 827 --PGP----GPGPGPGPIHIGGPPGFASSSGKPG 854
              GP    GP   PGP    GP GF  + G+PG
Sbjct: 198 VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 231



 Score = 33.9 bits (76), Expect = 0.72
 Identities = 27/80 (33%), Positives = 32/80 (40%), Gaps = 3/80 (3%)

Query: 776 PNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGP 835
           P +L+  SG   GP+     PG +    G   GPPG    P    GP       G    P
Sbjct: 90  PTDLATASG-QPGPKGQKGEPGDIKDIVG-PKGPPG-PQGPAGEQGPRGDRGDKGEKGAP 146

Query: 836 GPIHIGGPPGFASSSGKPGP 855
           GP    G PG   + G PGP
Sbjct: 147 GPRGRDGEPGTPGNPGPPGP 166



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 28/75 (37%), Positives = 30/75 (40%), Gaps = 7/75 (9%)

Query: 188  PPIPPIPAMPSLPPMPSIPPIPVPPPVP------TLPPVPPVPPIPPVPSVPPMTPLPPM 241
            P  PP P  PS     +  P P+ PP P      T P  PP  P PP P  PP  P   M
Sbjct: 1162 PRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP-GPGIDM 1220

Query: 242  SGMPPLNPPPVAPLP 256
            S    L P    P P
Sbjct: 1221 SAFAGLGPREKGPDP 1235


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 93.6 bits (231), Expect = 8e-19
 Identities = 95/271 (35%), Positives = 100/271 (36%), Gaps = 51/271 (18%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPNA----GLPGV-GLPSA-------GLPGAGLPSTGLP 678
           PP +G K     VPG    PG+       G PG  G P A       GLPG   P T  P
Sbjct: 604 PPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGT--PGTDGP 661

Query: 679 GSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSK----EANNGPPFNFPGNFGGSNAFG 734
             A   AG PGA  P  G+    GE  A    G K    +     P   PG  GG    G
Sbjct: 662 KGASGPAGPPGAQGPP-GLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTG 720

Query: 735 PPIPPPGLGG--GAFGDARPGMP--SVGNSGLPG----LGLDVPGFGGGPNNLSGPSGFG 786
           P I PPG  G  G  G+  P  P  S G  G PG     G   P    GP    G  G  
Sbjct: 721 P-IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 779

Query: 787 G--------------GPQNFGNGPGSLG-----GPPGF--GSGPPGLGSAPGHLG--GPP 823
           G              GPQ     PG  G     GP G     GPPG    PG  G  GPP
Sbjct: 780 GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP 839

Query: 824 AFGPGPGPGPGPGPIHIGGPPGFASSSGKPG 854
                PGP   PGP    GP G    SG PG
Sbjct: 840 GSNGNPGPPGPPGPSGKDGPKGARGDSGPPG 870



 Score = 80.1 bits (196), Expect = 9e-15
 Identities = 91/263 (34%), Positives = 101/263 (38%), Gaps = 47/263 (17%)

Query: 630 NPPAQGKKGLKMPVP--GNPAVPGMPN----AGLPGVGLPSAGLPGA----GLPST-GLP 678
           NP   G+ G+  P+   G P  PG P     AG PG      G PG     G P T GLP
Sbjct: 157 NPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKA-GERGPPGPQGARGFPGTPGLP 215

Query: 679 GSAITSAGLPG--AGMPSAGIPSAGGEEHAFLTVGSKEANNGP----PFNFPGNFGGSNA 732
           G      G PG       AG P   GE       GS   N  P    P   PG  G +  
Sbjct: 216 GVK-GHRGYPGLDGAKGEAGAPGVKGES------GSPGENGSPGPMGPRGLPGERGRTG- 267

Query: 733 FGPPIPPPGLGGGAFGDARPGMPS----VGNSGLPGLGLDVPGFGG--GPNNLSGPSGFG 786
                 P G  G    D +PG       VG +G PG     PG  G  GP    GP G  
Sbjct: 268 ------PAGAAGARGNDGQPGPAGPPGPVGPAGGPGFP-GAPGAKGEAGPTGARGPEG-A 319

Query: 787 GGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFG----PG-PGPGPGPGPIHIG 841
            GP+     PGS G  P   SG PG    PG  G   A G    PG PGP   PGP    
Sbjct: 320 QGPRGEPGTPGSPG--PAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 377

Query: 842 GPPGFASSSGKPGPTVIKVQNMP 864
           GP G    +G+PG    K +  P
Sbjct: 378 GPLGPKGQTGEPGIAGFKGEQGP 400



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 92/253 (36%), Positives = 101/253 (39%), Gaps = 52/253 (20%)

Query: 634 QGKKGLKMPVPGNPAVPGMPNA----GLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPG 689
           QGK G     PG    PG P      G PGV     G PG    + G PG A    GLPG
Sbjct: 503 QGKVG-PSGAPGEDGRPGPPGPQGARGQPGV----MGFPGPK-GANGEPGKA-GEKGLPG 555

Query: 690 A-GMPSAGIPSAGGEEHAFLTVG-SKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAF 747
           A G+   G+P   GE  A    G +  A        PG  G     GPP  PPG GG   
Sbjct: 556 APGL--RGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP-GPPGEGG--- 609

Query: 748 GDARPGMPSV-GNSGLPGL-----GLDVPGFGGGPN--NLSGPSGFGGGPQNFG-NGPGS 798
              +PG   V G +G PGL         PG  G P    L GP G  G P   G  G   
Sbjct: 610 ---KPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASG 666

Query: 799 LGGPPGFGSGPPGLGSAPGHLGGPPAFGP----------GPGPGPG-------PGPIHIG 841
             GPPG   GPPGL   PG  G     GP          GP   PG        GPI   
Sbjct: 667 PAGPPG-AQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI--- 722

Query: 842 GPPGFASSSGKPG 854
           GPPG A ++G+ G
Sbjct: 723 GPPGPAGANGEKG 735



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 98/288 (34%), Positives = 107/288 (37%), Gaps = 71/288 (24%)

Query: 633 AQGKKGLKMP--VPGNPAVPGMPNA-GLPGV-GLP----SAGLPG-AGLPS--------- 674
           A+G +G + P   PG P  PG   A G PG  G+P    SAG PG AG P          
Sbjct: 313 ARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPG 372

Query: 675 -------------TGLPGSAITSA-----GLPGAGMPSAGIPSAGGEEHAFLTVGSK--- 713
                        TG PG A         G PG   P  G P   GEE      G     
Sbjct: 373 PQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ-GAPGPAGEEGKRGARGEPGGV 431

Query: 714 -----EANNGPPFN--FPGNFGGSNAFGPPIP--PPGLGGGAFGDARPGMPSVGNSGLPG 764
                    G P N  FPG  G +   G P    P GL G    +  PG P  G  GLPG
Sbjct: 432 GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRP--GEPGLPG 489

Query: 765 L-GLDVPGFGGGPNNLSGPSGFGG--------GPQNFGNGPGSLG--GPPGFG-----SG 808
             GL       GP    GPSG  G        GPQ     PG +G  GP G       +G
Sbjct: 490 ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG 549

Query: 809 PPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGPT 856
             GL  APG  G P   G     GP PGP    GP G     G PGP+
Sbjct: 550 EKGLPGAPGLRGLPGKDGETGAAGP-PGP---AGPAGERGEQGAPGPS 593



 Score = 74.3 bits (181), Expect = 5e-13
 Identities = 85/261 (32%), Positives = 95/261 (36%), Gaps = 40/261 (15%)

Query: 628 EKNPPAQGKKGLKMPVPGNPAVPGMPNA-GLPGVGLPSAG---------LPGAGLPSTGL 677
           EK  P    +  +   PGNP  PG P   G PG+G   A            GA L     
Sbjct: 73  EKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQG 132

Query: 678 PGSAITSAGLPG-AGMPSA----GIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNA 732
           P   +   G PG AG P      G P   GE      +G +    GPP   PG  G    
Sbjct: 133 PMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPR----GPP-GPPGKPGDDGE 187

Query: 733 FGPPIP-----PPGLGGGAFGDARPGMPSV-GNSGLPGLG-----LDVPGFGG-----GP 776
            G P       PPG  G       PG+P V G+ G PGL         PG  G     G 
Sbjct: 188 AGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGE 247

Query: 777 NNLSGPSGFGGGPQNFGN-GPGSLGGPPGFGSGPPGLGSAPGHLG--GPPAFGPGPGPGP 833
           N   GP G  G P   G  GP    G  G   G PG    PG +G  G P F   PG   
Sbjct: 248 NGSPGPMGPRGLPGERGRTGPAGAAGARG-NDGQPGPAGPPGPVGPAGGPGFPGAPGAKG 306

Query: 834 GPGPIHIGGPPGFASSSGKPG 854
             GP    GP G     G+PG
Sbjct: 307 EAGPTGARGPEGAQGPRGEPG 327



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 92/269 (34%), Positives = 101/269 (37%), Gaps = 61/269 (22%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPN-------AGLPGVGLPSA-----GLPGA----GLPS 674
           P   G+KGL    PG P + G+P        AG PG   P+      G PG     GLP 
Sbjct: 545 PGKAGEKGL----PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPG 600

Query: 675 TGLP---GSAITSAGLPG-AGMPSA-------GIPSAGGEEHAFLTVGSKEANNGPPFNF 723
              P   G      G+PG AG P         G P   G   A    G +    G P   
Sbjct: 601 PPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPR----GLP-GT 655

Query: 724 PGNFGGSNAFGPPIPP-----PGLGG-----GAFGDARP--GMPSVGNSGLPGLGLDVPG 771
           PG  G   A GP  PP     PGL G     GA G A P      VG  G  G     PG
Sbjct: 656 PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEG----APG 711

Query: 772 FGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLG-----GPPAFG 826
             GG   L+GP G   GP    NG     GPPG  +G  G   APG  G     GP  F 
Sbjct: 712 KDGG-RGLTGPIG-PPGPAG-ANGEKGEVGPPG-PAGSAGARGAPGERGETGPPGPAGFA 767

Query: 827 PGPGPGPGPGPIHIGGPPGFASSSGKPGP 855
             PG    PG     G  G    +G PGP
Sbjct: 768 GPPGADGQPGAKGEQGEAGQKGDAGAPGP 796



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 84/250 (33%), Positives = 91/250 (36%), Gaps = 36/250 (14%)

Query: 631  PPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSA-GLPGAGLPSTGLPGSAITSAGLPG 689
            P  QG  G   P P  P     P       G P A G PGA     G PGS   + G PG
Sbjct: 794  PGPQGPSGA--PGPQGPTGVTGPKGARGAQGPPGATGFPGAA-GRVGPPGSN-GNPGPPG 849

Query: 690  AGMPSA--GIPSAGGEEHAFLTVGSK--EANNGPPFNF--PGNFGGSNAFGPPIPPPGLG 743
               PS   G   A G+       G    +   GPP     PG+ G S A GPP  P GL 
Sbjct: 850  PPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPP-GPQGLA 908

Query: 744  GGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPP 803
            G       PG    G  G PGL    PG  G P     P   G        GP  L GP 
Sbjct: 909  GQRGIVGLPGQR--GERGFPGL----PGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA 962

Query: 804  GF--------GSGPPGLGSAPG---------HLGGPPAFGPGPGPGPGPGPIHIGGPPGF 846
            G           GPPG   A G          +G P A GP   PGP  GP    G  G 
Sbjct: 963  GEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPA-GPTGKQGDRGE 1021

Query: 847  ASSSGKPGPT 856
            A + G  GP+
Sbjct: 1022 AGAQGPMGPS 1031



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 83/259 (32%), Positives = 94/259 (36%), Gaps = 45/259 (17%)

Query: 621  LEDMREIEKNPPAQGKKGLKMPVPGNPAVPGMPNA-GLPGVGLPSAGLPG-AGLPSTGLP 678
            L   R I   P  +G++G     PG P   G P   G PG      G PG  G P    P
Sbjct: 907  LAGQRGIVGLPGQRGERGF----PGLPGPSGEPGKQGAPGAS-GDRGPPGPVGPPGLTGP 961

Query: 679  GSAITSAGLPGAGMP-----SAGIPSAGGEEHAFLTVGSKEANNGP----PFNFPGNFGG 729
                   G PGA  P     +AG+    GE  A    G+      P    P    G+ G 
Sbjct: 962  AGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGE 1021

Query: 730  SNAFGP--PIPPPGLGG-----GAFGD----ARPGMPSV-GNSGLPGL-GLDVPGFGGGP 776
            + A GP  P  P G  G     G  GD      PG   + G+ G  GL GL  P    G 
Sbjct: 1022 AGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGD 1081

Query: 777  NNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPG 836
               SGP+G           P    GPPG    P G     G  G P   GP PGP    G
Sbjct: 1082 QGASGPAG-----------PSGPRGPPG----PVGPSGKDGANGIPGPIGP-PGPRGRSG 1125

Query: 837  PIHIGGPPGFASSSGKPGP 855
                 GPPG     G PGP
Sbjct: 1126 ETGPAGPPGNPGPPGPPGP 1144



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 86/273 (31%), Positives = 98/273 (35%), Gaps = 50/273 (18%)

Query: 628  EKNPPAQ-GKKGLKMPV--PGNPAVPGMPN-AGLPGVGLPSAGLPGAGLPSTGLPGSAIT 683
            +  PP + G+ GL+ P   PG    PG    +G  G   P       G+   GLPG    
Sbjct: 865  DSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGI--VGLPGQR-G 921

Query: 684  SAGLPGAGMPSA-----GIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIP 738
              G PG   PS      G P A G+      VG        P   PG  G   A GPP  
Sbjct: 922  ERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTG--PAGEPGREGSPGADGPPGR 979

Query: 739  PPGLG--------GGAFGDARPGMP-SVGNSGLPGLGLDVPGFGG-GPNNLSGPSGFGG- 787
                G        G       PG P S G +G  G   D    G  GP   SGP+G  G 
Sbjct: 980  DGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI 1039

Query: 788  -GPQNFGNGPGSLGGPPGFG-------SGPPGLGSAPGHLGGPPAFGPG--------PGP 831
             GPQ      G  G P   G       +G  GL   PG  G   A GP         PGP
Sbjct: 1040 QGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGP 1099

Query: 832  -GPG--------PGPIHIGGPPGFASSSGKPGP 855
             GP         PGPI   GP G +  +G  GP
Sbjct: 1100 VGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP 1132



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 42/132 (31%), Positives = 46/132 (34%), Gaps = 39/132 (29%)

Query: 758 GNSGLPGLGLDVPGFGGGPNNLSGPSGFGG--GPQNFGNGPGSLGGP-PGFGSGPPGLGS 814
           G  G PG   D+ G  G P    GP G  G  GP+      G  G P P    G PG   
Sbjct: 35  GQKGEPGDIKDIVGPKGPP----GPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPG 90

Query: 815 APGHLG-----GPPAFG-----------------------PGP----GPGPGPGPIHIGG 842
            PG  G     GPP  G                        GP    GP   PGP    G
Sbjct: 91  NPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 150

Query: 843 PPGFASSSGKPG 854
           P GF  + G+PG
Sbjct: 151 PQGFQGNPGEPG 162



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 28/75 (37%), Positives = 30/75 (40%), Gaps = 7/75 (9%)

Query: 188  PPIPPIPAMPSLPPMPSIPPIPVPPPVP------TLPPVPPVPPIPPVPSVPPMTPLPPM 241
            P  PP P  PS     +  P P+ PP P      T P  PP  P PP P  PP  P   M
Sbjct: 1093 PRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP-GPGIDM 1151

Query: 242  SGMPPLNPPPVAPLP 256
            S    L P    P P
Sbjct: 1152 SAFAGLGPREKGPDP 1166



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 23/68 (33%), Positives = 26/68 (38%), Gaps = 2/68 (2%)

Query: 788 GPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFA 847
           GP+     PG +    G   GPPG    P    GP       G    PGP    G PG  
Sbjct: 32  GPKGQKGEPGDIKDIVG-PKGPPG-PQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP 89

Query: 848 SSSGKPGP 855
            + G PGP
Sbjct: 90  GNPGPPGP 97


>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 91/251 (36%), Positives = 103/251 (41%), Gaps = 47/251 (18%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSA-----GLPGA----------GLPST 675
           P  +G++GL    PG P  PG+P  G PG   P       G+PGA          G P  
Sbjct: 330 PGGKGEQGL----PGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGI 385

Query: 676 GLPGSAITSAGLPGA-GMPSA-GIPSAGGEEHAFLTVGSKEANNGPPFN-FPGNFGGSNA 732
           G P       G+PG  G P A G P   GE       G       P    FPG  G    
Sbjct: 386 GGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGE 445

Query: 733 FGPP----IPPP-GLGGGAFGDARPGMPSV-------GNSGLPG-LGLD----VPGFGGG 775
            GPP    +P P G  G A     PG+P V       G  G+PG  GL     +PG GG 
Sbjct: 446 VGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGG- 504

Query: 776 PNNLSGPSGFGGGPQNFGNGPGSLGGPPGF-GSGPPGLGSAPGHLGGPPAFGPGPGPGPG 834
           P+   GP G  G       G   L GPPGF G G PG+    G  G P A GP   PG  
Sbjct: 505 PSGPIGPPGIPGP-----KGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGL- 558

Query: 835 PGPIHIGGPPG 845
           PGP    GPPG
Sbjct: 559 PGPPGPPGPPG 569



 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 98/286 (34%), Positives = 110/286 (38%), Gaps = 68/286 (23%)

Query: 631 PPAQGKKGLKMP--VPGNPAVPGMPNAGLPGV-GLPSA-GLPGA----GLPSTGLPGSAI 682
           P A G+ G + P  VPG    PG+P  G PG  G+P   G PG     GLP  GLPG   
Sbjct: 289 PGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLP--GLPGPP- 345

Query: 683 TSAGLPGAGMPS----------AGIPSAGGEEHAFLTVGSKEANN--------------G 718
              GLPG G P            G+P A G       +G+                   G
Sbjct: 346 ---GLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMG 402

Query: 719 PP--FNFPGNFGGSNAFGPPIPP-----PGLGG-----GAFGDARP----GMPS------ 756
           PP    FPG  G     GP  PP     PGL G     G  G+  P    G+P       
Sbjct: 403 PPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKG 462

Query: 757 -VGNSGLPGLGLDVPGFGG--GPNNLSGPSGFGGGPQNFG-NGPGSLGGPPGFGS--GPP 810
             G  G+PGL   VPG  G  G   + G  G  G P   G  GP    GPPG     G P
Sbjct: 463 EAGQKGVPGLP-GVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEP 521

Query: 811 GLGSAPGHLG-GPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGP 855
           GL   PG  G G P      GP   PG +   G PG     G PGP
Sbjct: 522 GLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGP 567



 Score = 88.2 bits (217), Expect = 3e-17
 Identities = 81/227 (35%), Positives = 96/227 (42%), Gaps = 54/227 (23%)

Query: 634 QGKKGLKMPVPGNPAVPGMPNAGLPGV-GLPSA-GLPGAGLPSTGLPGSAITSAGLPGAG 691
           QG +G   P  G P  PG+P  G+PG+ G P   G PG G P  G+PG      G PGA 
Sbjct: 120 QGPRGEPGP-RGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKP--GMPGMP----GKPGA- 171

Query: 692 MPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAFGDAR 751
               G+P A GE      +G K           G  G     GP  PP            
Sbjct: 172 ---MGMPGAKGE------IGQK-----------GEIGPMGIPGPQGPP----------GP 201

Query: 752 PGMPSVGNSGLPGL-GLDVPGFGGGPNNLSGPSGFGG--GPQNFGNGPGSLGGPPGFGSG 808
            G+P +G  G PGL G   P    GP  L GP G  G  G + FG     + G PG   G
Sbjct: 202 HGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFG-----MPGAPGV-KG 255

Query: 809 PPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGP 855
           PPG+   PG +G P    PG    PGP      GP G   + G+PGP
Sbjct: 256 PPGMHGPPGPVGLPGVGKPGVTGFPGP-----QGPLGKPGAPGEPGP 297



 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 96/292 (32%), Positives = 109/292 (37%), Gaps = 75/292 (25%)

Query: 627 IEKNPPAQGKKGLKMP----VPGNPAVPGMPNA-------------GLPGV-------GL 662
           I+  P  QG  G+  P    +PG P   GMP A             G+PG        GL
Sbjct: 145 IKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGL 204

Query: 663 PSAGLPGA-GLPSTGLPGSAITSAGLPGA-------GMPSAGIPSAGGEEHAFLTVGSKE 714
           P  G PG  GLP    P       GLPG        G    G+P A G       V    
Sbjct: 205 PGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPG-------VKGPP 257

Query: 715 ANNGPP--FNFPGNFGGSNAFGPPIPPPGLGG-GAFGDARP----GMPSV-GNSGLPGLG 766
             +GPP     PG  G     G P P   LG  GA G+  P    G+P V G  G+PG+G
Sbjct: 258 GMHGPPGPVGLPG-VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIG 316

Query: 767 LD-------VPGFGGGPNN-----LSGPSGFGG----------GPQNFGNGPGSLGGPPG 804
                     PGF GG        L GP G  G          G +  G  PG+LG    
Sbjct: 317 KPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGE 376

Query: 805 FGS-GPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGP 855
            G  G PG+G  PG  G P      PGP   PG I   GP G     G  GP
Sbjct: 377 KGPIGAPGIGGPPGEPGLPGI----PGPMGPPGAIGFPGPKGEGGIVGPQGP 424



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 58/178 (32%), Positives = 67/178 (37%), Gaps = 25/178 (14%)

Query: 688 PGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAF 747
           P   M    +P  G E    + + S     GP        G     GPP  PPGL G   
Sbjct: 95  PAPRMGKEAVPKKGKE----IPLASLRGEQGPR-------GEPGPRGPP-GPPGLPGHGI 142

Query: 748 GDARPGMPSVGNSGLPGLGLD-VPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFG 806
              + G P  G  G PG+G   +PG  G P  +  P   G   Q    GP  + GP    
Sbjct: 143 PGIK-GKP--GPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGP---- 195

Query: 807 SGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGPTVIKVQNMP 864
            GPPG    PG +G P     GPG    PGP    GP G     G  GP   K   MP
Sbjct: 196 QGPPGPHGLPG-IGKPG----GPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMP 248



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 59/197 (29%), Positives = 75/197 (38%), Gaps = 41/197 (20%)

Query: 611 GREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPAVPGM----PNAGLPG------- 659
           G+  F+  V    MR +      +G+ G K  VPG P VPG+       G+PG       
Sbjct: 438 GKPGFLGEVGPPGMRGLPGPIGPKGEAGQK-GVPGLPGVPGLLGPKGEPGIPGDQGLQGP 496

Query: 660 VGLPSAGLPGAGLPSTGLPGSAITSAGLPGA-GMPSAGIPSAGGEEHAFLTVGSKEANNG 718
            G+P  G P   +   G+PG      GLPG  G P  G P   G              +G
Sbjct: 497 PGIPGIGGPSGPIGPPGIPGPK-GEPGLPGPPGFPGIGKPGVAGL-------------HG 542

Query: 719 PPFNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNN 778
           PP       G   A GP    PGL G       PG P+V     P  G  +P  G G + 
Sbjct: 543 PP-------GKPGALGPQ-GQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDG 594

Query: 779 LSGPSGFG------GGP 789
           +  P  +G      GGP
Sbjct: 595 VKPPHAYGAKKGKNGGP 611



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 36/114 (31%), Positives = 40/114 (35%), Gaps = 24/114 (21%)

Query: 175 VPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVP-------PP------VPTLPPVP 221
           +P    P   + PP IP     P LP  P  P I  P       PP       P   P  
Sbjct: 499 IPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGL 558

Query: 222 PVPPIPPVPSVPP--MTPLPPMS---------GMPPLNPPPVAPLPAGMNGSGA 264
           P PP PP P  PP  M P PP           G+  + PP       G NG  A
Sbjct: 559 PGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPA 612



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 36/112 (32%), Positives = 40/112 (35%), Gaps = 14/112 (12%)

Query: 175 VPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPP 234
           VP        + P   P IP    L   P IP I  P         P  PP  P P   P
Sbjct: 469 VPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSG-------PIGPPGIPGPKGEP 521

Query: 235 MTPLPPMSGMPPLNPPPVAPLPAGMNG-SGAPMNLNNNLNPMFLGPLNPVNP 285
             P PP  G P +  P V    AG++G  G P  L     P   GP  P  P
Sbjct: 522 GLPGPP--GFPGIGKPGV----AGLHGPPGKPGALGPQGQPGLPGPPGPPGP 567



 Score = 33.5 bits (75), Expect = 0.95
 Identities = 33/133 (24%), Positives = 47/133 (35%), Gaps = 10/133 (7%)

Query: 162 MGASFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLP---PMPSIPPIPVPPPVPTLP 218
           MG       +    P     M  + P P     A+P      P+ S+     P   P  P
Sbjct: 70  MGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPG-P 128

Query: 219 PVPPVPPIPPVPSVPPMTPLPPMSGMPPLNPPPVAPLPA-----GMNGSGAPMNLNNNLN 273
             PP PP  P   +P +   P   G P +  P +  +P      GM G+   +     + 
Sbjct: 129 RGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIG 188

Query: 274 PMFL-GPLNPVNP 285
           PM + GP  P  P
Sbjct: 189 PMGIPGPQGPPGP 201


>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 91/251 (36%), Positives = 103/251 (41%), Gaps = 47/251 (18%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSA-----GLPGA----------GLPST 675
           P  +G++GL    PG P  PG+P  G PG   P       G+PGA          G P  
Sbjct: 330 PGGKGEQGL----PGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGI 385

Query: 676 GLPGSAITSAGLPGA-GMPSA-GIPSAGGEEHAFLTVGSKEANNGPPFN-FPGNFGGSNA 732
           G P       G+PG  G P A G P   GE       G       P    FPG  G    
Sbjct: 386 GGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGE 445

Query: 733 FGPP----IPPP-GLGGGAFGDARPGMPSV-------GNSGLPG-LGLD----VPGFGGG 775
            GPP    +P P G  G A     PG+P V       G  G+PG  GL     +PG GG 
Sbjct: 446 VGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGG- 504

Query: 776 PNNLSGPSGFGGGPQNFGNGPGSLGGPPGF-GSGPPGLGSAPGHLGGPPAFGPGPGPGPG 834
           P+   GP G  G       G   L GPPGF G G PG+    G  G P A GP   PG  
Sbjct: 505 PSGPIGPPGIPGP-----KGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGL- 558

Query: 835 PGPIHIGGPPG 845
           PGP    GPPG
Sbjct: 559 PGPPGPPGPPG 569



 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 98/286 (34%), Positives = 110/286 (38%), Gaps = 68/286 (23%)

Query: 631 PPAQGKKGLKMP--VPGNPAVPGMPNAGLPGV-GLPSA-GLPGA----GLPSTGLPGSAI 682
           P A G+ G + P  VPG    PG+P  G PG  G+P   G PG     GLP  GLPG   
Sbjct: 289 PGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLP--GLPGPP- 345

Query: 683 TSAGLPGAGMPS----------AGIPSAGGEEHAFLTVGSKEANN--------------G 718
              GLPG G P            G+P A G       +G+                   G
Sbjct: 346 ---GLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMG 402

Query: 719 PP--FNFPGNFGGSNAFGPPIPP-----PGLGG-----GAFGDARP----GMPS------ 756
           PP    FPG  G     GP  PP     PGL G     G  G+  P    G+P       
Sbjct: 403 PPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKG 462

Query: 757 -VGNSGLPGLGLDVPGFGG--GPNNLSGPSGFGGGPQNFG-NGPGSLGGPPGFGS--GPP 810
             G  G+PGL   VPG  G  G   + G  G  G P   G  GP    GPPG     G P
Sbjct: 463 EAGQKGVPGLP-GVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEP 521

Query: 811 GLGSAPGHLG-GPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGP 855
           GL   PG  G G P      GP   PG +   G PG     G PGP
Sbjct: 522 GLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGP 567



 Score = 88.2 bits (217), Expect = 3e-17
 Identities = 81/227 (35%), Positives = 96/227 (42%), Gaps = 54/227 (23%)

Query: 634 QGKKGLKMPVPGNPAVPGMPNAGLPGV-GLPSA-GLPGAGLPSTGLPGSAITSAGLPGAG 691
           QG +G   P  G P  PG+P  G+PG+ G P   G PG G P  G+PG      G PGA 
Sbjct: 120 QGPRGEPGP-RGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKP--GMPGMP----GKPGA- 171

Query: 692 MPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAFGDAR 751
               G+P A GE      +G K           G  G     GP  PP            
Sbjct: 172 ---MGMPGAKGE------IGQK-----------GEIGPMGIPGPQGPP----------GP 201

Query: 752 PGMPSVGNSGLPGL-GLDVPGFGGGPNNLSGPSGFGG--GPQNFGNGPGSLGGPPGFGSG 808
            G+P +G  G PGL G   P    GP  L GP G  G  G + FG     + G PG   G
Sbjct: 202 HGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFG-----MPGAPGV-KG 255

Query: 809 PPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGP 855
           PPG+   PG +G P    PG    PGP      GP G   + G+PGP
Sbjct: 256 PPGMHGPPGPVGLPGVGKPGVTGFPGP-----QGPLGKPGAPGEPGP 297



 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 96/292 (32%), Positives = 109/292 (37%), Gaps = 75/292 (25%)

Query: 627 IEKNPPAQGKKGLKMP----VPGNPAVPGMPNA-------------GLPGV-------GL 662
           I+  P  QG  G+  P    +PG P   GMP A             G+PG        GL
Sbjct: 145 IKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGL 204

Query: 663 PSAGLPGA-GLPSTGLPGSAITSAGLPGA-------GMPSAGIPSAGGEEHAFLTVGSKE 714
           P  G PG  GLP    P       GLPG        G    G+P A G       V    
Sbjct: 205 PGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPG-------VKGPP 257

Query: 715 ANNGPP--FNFPGNFGGSNAFGPPIPPPGLGG-GAFGDARP----GMPSV-GNSGLPGLG 766
             +GPP     PG  G     G P P   LG  GA G+  P    G+P V G  G+PG+G
Sbjct: 258 GMHGPPGPVGLPG-VGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIG 316

Query: 767 LD-------VPGFGGGPNN-----LSGPSGFGG----------GPQNFGNGPGSLGGPPG 804
                     PGF GG        L GP G  G          G +  G  PG+LG    
Sbjct: 317 KPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGE 376

Query: 805 FGS-GPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGP 855
            G  G PG+G  PG  G P      PGP   PG I   GP G     G  GP
Sbjct: 377 KGPIGAPGIGGPPGEPGLPGI----PGPMGPPGAIGFPGPKGEGGIVGPQGP 424



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 58/178 (32%), Positives = 67/178 (37%), Gaps = 25/178 (14%)

Query: 688 PGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAF 747
           P   M    +P  G E    + + S     GP        G     GPP  PPGL G   
Sbjct: 95  PAPRMGKEAVPKKGKE----IPLASLRGEQGPR-------GEPGPRGPP-GPPGLPGHGI 142

Query: 748 GDARPGMPSVGNSGLPGLGLD-VPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFG 806
              + G P  G  G PG+G   +PG  G P  +  P   G   Q    GP  + GP    
Sbjct: 143 PGIK-GKP--GPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGP---- 195

Query: 807 SGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGPTVIKVQNMP 864
            GPPG    PG +G P     GPG    PGP    GP G     G  GP   K   MP
Sbjct: 196 QGPPGPHGLPG-IGKPG----GPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMP 248



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 59/197 (29%), Positives = 75/197 (38%), Gaps = 41/197 (20%)

Query: 611 GREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPAVPGM----PNAGLPG------- 659
           G+  F+  V    MR +      +G+ G K  VPG P VPG+       G+PG       
Sbjct: 438 GKPGFLGEVGPPGMRGLPGPIGPKGEAGQK-GVPGLPGVPGLLGPKGEPGIPGDQGLQGP 496

Query: 660 VGLPSAGLPGAGLPSTGLPGSAITSAGLPGA-GMPSAGIPSAGGEEHAFLTVGSKEANNG 718
            G+P  G P   +   G+PG      GLPG  G P  G P   G              +G
Sbjct: 497 PGIPGIGGPSGPIGPPGIPGPK-GEPGLPGPPGFPGIGKPGVAGL-------------HG 542

Query: 719 PPFNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNN 778
           PP       G   A GP    PGL G       PG P+V     P  G  +P  G G + 
Sbjct: 543 PP-------GKPGALGPQ-GQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDG 594

Query: 779 LSGPSGFG------GGP 789
           +  P  +G      GGP
Sbjct: 595 VKPPHAYGAKKGKNGGP 611



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 36/114 (31%), Positives = 40/114 (35%), Gaps = 24/114 (21%)

Query: 175 VPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVP-------PP------VPTLPPVP 221
           +P    P   + PP IP     P LP  P  P I  P       PP       P   P  
Sbjct: 499 IPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGL 558

Query: 222 PVPPIPPVPSVPP--MTPLPPMS---------GMPPLNPPPVAPLPAGMNGSGA 264
           P PP PP P  PP  M P PP           G+  + PP       G NG  A
Sbjct: 559 PGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPA 612



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 36/112 (32%), Positives = 40/112 (35%), Gaps = 14/112 (12%)

Query: 175 VPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPP 234
           VP        + P   P IP    L   P IP I  P         P  PP  P P   P
Sbjct: 469 VPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSG-------PIGPPGIPGPKGEP 521

Query: 235 MTPLPPMSGMPPLNPPPVAPLPAGMNG-SGAPMNLNNNLNPMFLGPLNPVNP 285
             P PP  G P +  P V    AG++G  G P  L     P   GP  P  P
Sbjct: 522 GLPGPP--GFPGIGKPGV----AGLHGPPGKPGALGPQGQPGLPGPPGPPGP 567



 Score = 33.5 bits (75), Expect = 0.95
 Identities = 33/133 (24%), Positives = 47/133 (35%), Gaps = 10/133 (7%)

Query: 162 MGASFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLP---PMPSIPPIPVPPPVPTLP 218
           MG       +    P     M  + P P     A+P      P+ S+     P   P  P
Sbjct: 70  MGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPG-P 128

Query: 219 PVPPVPPIPPVPSVPPMTPLPPMSGMPPLNPPPVAPLPA-----GMNGSGAPMNLNNNLN 273
             PP PP  P   +P +   P   G P +  P +  +P      GM G+   +     + 
Sbjct: 129 RGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIG 188

Query: 274 PMFL-GPLNPVNP 285
           PM + GP  P  P
Sbjct: 189 PMGIPGPQGPPGP 201


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 91.3 bits (225), Expect = 4e-18
 Identities = 101/258 (39%), Positives = 111/258 (43%), Gaps = 52/258 (20%)

Query: 628 EKNPPAQGKKGLKMPV--------PGNPAVPGMPNA-GLPGVGLPSAGLPGA-GLPSTGL 677
           EK P   G++G   P         PG   VPG P   G+PG    S G PG+ G P  G 
Sbjct: 502 EKGPA--GERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPG----SPGGPGSDGKP--GP 553

Query: 678 PGSAITSAGLPGAGMPSA--------GIPSAGGEEHAFLTVGSKEANNGP-PFNFPGNFG 728
           PGS   S G PG   PS         G P   G + A    G +    GP P   PG  G
Sbjct: 554 PGSQGES-GRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNG 612

Query: 729 GSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGG 788
            +   GPP  P G GG   GD  P  P  G  GLPG G   PG  G P    GP G  G 
Sbjct: 613 ETGPQGPP-GPTGPGGDK-GDTGPPGPQ-GLQGLPGTG-GPPGENGKPGE-PGPKGDAGA 667

Query: 789 PQNFGNGPGSLG--GPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGF 846
           P      PG  G  G PG   GPPGL  APG  GG    GP PGP  G G     GPPG 
Sbjct: 668 P----GAPGGKGDAGAPG-ERGPPGLAGAPGLRGGA---GP-PGPEGGKGA---AGPPGP 715

Query: 847 ASSSGKPGPTVIKVQNMP 864
             ++G PG     +Q MP
Sbjct: 716 PGAAGTPG-----LQGMP 728



 Score = 87.4 bits (215), Expect = 6e-17
 Identities = 96/300 (32%), Positives = 108/300 (36%), Gaps = 84/300 (28%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPN-------AGLPGV-GLPSAGLPGAGLPSTGLPGSAI 682
           P  QG  G + P PG P + G P        AG+PG  GL  A  P     + G PG   
Sbjct: 371 PGPQGHAGAQGP-PGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLR- 428

Query: 683 TSAGLPG----------------AGMPSAGIPSAGGEEHAFLTVGSKEANNGP------- 719
             AG PG                AG+P  G+P A GE+    + G   AN  P       
Sbjct: 429 GGAGEPGKNGAKGEPGPRGERGEAGIP--GVPGAKGEDGKDGSPGEPGANGLPGAAGERG 486

Query: 720 ---------PFNFPGNFGGSNAFGPPIPP-----------------------PGLGGGAF 747
                    P   PG  G +   G P P                        PG  GG  
Sbjct: 487 APGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPG 546

Query: 748 GDARPGMP-SVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFG--NGPGSLGGPPG 804
            D +PG P S G SG PG     P    GP    G  GF G   N G     G  GGP G
Sbjct: 547 SDGKPGPPGSQGESGRPG-----PPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGG 601

Query: 805 FG-SGPPGLGSAPGHLGGPPAFGPGPGPG----PGPGPIH----IGGPPGFASSSGKPGP 855
            G  GPPG     G  G P   GPG   G    PGP  +      GGPPG     G+PGP
Sbjct: 602 PGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGP 661



 Score = 87.4 bits (215), Expect = 6e-17
 Identities = 92/263 (34%), Positives = 100/263 (38%), Gaps = 52/263 (19%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPN-------AGLPGVGLPSAGLPGAGLPSTGLPGSAIT 683
           P   G +G   P+ G P   G P         GLPG+  P  G PG     TG PG A  
Sbjct: 755 PGKDGPRGPTGPI-GPPGPAGQPGDKGEGGAPGLPGIAGPR-GSPGER-GETGPPGPA-- 809

Query: 684 SAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPP--PG 741
             G PGA   + G P   GE  A      ++   GPP    G  GGS   GPP P    G
Sbjct: 810 --GFPGAPGQN-GEPGGKGERGA----PGEKGEGGPP-GVAGPPGGSGPAGPPGPQGVKG 861

Query: 742 LGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGN-GPGSLG 800
             G   G    G P  G  GLPG     PG  G P    GP G  G P   G  GP    
Sbjct: 862 ERGSPGGPGAAGFP--GARGLPG----PPGSNGNP----GPPGPSGSPGKDGPPGPAGNT 911

Query: 801 GPPGFG--SGPPGLGSAPGHLGGPPAFGPGPGPGP-----------------GPGPIHIG 841
           G PG    SGP G    PG  G P A GP   PGP                  PGP    
Sbjct: 912 GAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSP 971

Query: 842 GPPGFASSSGKPGPTVIKVQNMP 864
           GP G    SGKPG   +  +  P
Sbjct: 972 GPQGVKGESGKPGANGLSGERGP 994



 Score = 86.7 bits (213), Expect = 9e-17
 Identities = 98/285 (34%), Positives = 106/285 (37%), Gaps = 65/285 (22%)

Query: 630 NPPAQGKKGLKMPVPGNPAVPGMP--NAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGL 687
           N  A GK G +   PG P   G P  N      G P    PG     TG PG      GL
Sbjct: 586 NDGAPGKNG-ERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQ-GL 643

Query: 688 PGAGMPSA-----GIPSAGGEEHAFLTVGSK-----EANNGPP-----------FNFPGN 726
           PG G P       G P   G+  A    G K         GPP              PG 
Sbjct: 644 PGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGP 703

Query: 727 FGGSNAFGPPIPP-----PGLGG-----GAFGDARPGMPSVGNSGLPG-LGLD-VPGFGG 774
            GG  A GPP PP     PGL G     G  G   P     G+ G PG  G D VPG  G
Sbjct: 704 EGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPK----GDKGEPGGPGADGVPGKDG 759

Query: 775 --GPNNLSGPSGFGGGPQNFGNG--------------PGSLG--GPPGFGSGPPGLGSAP 816
             GP    GP G  G P + G G              PG  G  GPPG    P G   AP
Sbjct: 760 PRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPG----PAGFPGAP 815

Query: 817 GHLGGPPAFGPGPGPGPGP--GPIHIGGPPGFASSSGKPGPTVIK 859
           G  G P   G    PG     GP  + GPPG +  +G PGP  +K
Sbjct: 816 GQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVK 860



 Score = 86.7 bits (213), Expect = 9e-17
 Identities = 93/246 (37%), Positives = 107/246 (43%), Gaps = 37/246 (15%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSAGLPG--AGLPSTGLPGSAITSAGLP 688
           P A G KG     PG    PG+  AG PG+    AG PG   G  + G PG    +AG P
Sbjct: 668 PGAPGGKG-DAGAPGERGPPGL--AGAPGLR-GGAGPPGPEGGKGAAGPPGPP-GAAGTP 722

Query: 689 GA-GMPS--AGIPSAGGEEHAFLTVGSKEANNGPPFN-FPGNFGGSNAFGPPIPPPGLGG 744
           G  GMP    G+ S G +       G K    GP  +  PG  G     GP I PPG  G
Sbjct: 723 GLQGMPGERGGLGSPGPK-------GDKGEPGGPGADGVPGKDGPRGPTGP-IGPPGPAG 774

Query: 745 --GAFGDA-RPGMPSV-GNSGLPG----LGLDVP-GFGGGPNNLSGPSGFG--GGPQNFG 793
             G  G+   PG+P + G  G PG     G   P GF G P     P G G  G P   G
Sbjct: 775 QPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKG 834

Query: 794 NG--PGSLGGPPGFG-SGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSS 850
            G  PG  G P G G +GPPG     G  G P     GPG    PG   + GPPG   + 
Sbjct: 835 EGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPG----GPGAAGFPGARGLPGPPGSNGNP 890

Query: 851 GKPGPT 856
           G PGP+
Sbjct: 891 GPPGPS 896



 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 102/310 (32%), Positives = 113/310 (36%), Gaps = 89/310 (28%)

Query: 631  PPAQGKKGLKMPVPGNPAVPGMPNA-GLPGV-------GLPS-AGLPGAGLP-----STG 676
            P  QG KG +   PG P   G P A GLPG        G P  +G PG   P     +TG
Sbjct: 854  PGPQGVKG-ERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTG 912

Query: 677  LPGSAITSAGLPGAGMPSA-GIPSAGGEEHAFLTVGSKEANN-----GPP---------- 720
             PGS   S     AG P   G P A G   A   +G           GPP          
Sbjct: 913  APGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPG 972

Query: 721  -------FNFPGNFGGSNAFGPPIPP--PGLGGGAFGDARPGMPSVGNSGLPGL------ 765
                      PG  G S   GPP P   PGL G A    R G P  G+ GLPG       
Sbjct: 973  PQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNP--GSDGLPGRDGSPGG 1030

Query: 766  --------GLDVPGFGG--GPNNLSGPSGFGG-----GPQNFGNGPGSLG--GPPGFGSG 808
                        PG  G  GP    GP+G  G     GP      PG  G  G PG   G
Sbjct: 1031 KGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPG-PQG 1089

Query: 809  PPG-------LGSA--------PGHLGGPPAFGPG--------PGPGPGPGPIHIGGPPG 845
            P G        G+A        PG+ G P + GP         PGP    GP+   GPPG
Sbjct: 1090 PRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPG 1149

Query: 846  FASSSGKPGP 855
               +SG PGP
Sbjct: 1150 KDGTSGHPGP 1159



 Score = 74.3 bits (181), Expect = 5e-13
 Identities = 88/265 (33%), Positives = 98/265 (36%), Gaps = 57/265 (21%)

Query: 644 PGNPAVPGMPNAGLPGVGLPSA--GLPGAGLPS--------TGLPGSAITSAGLPG---- 689
           PG+P   G P  G PG   PS   G PGA  PS        +G PG      GLPG    
Sbjct: 194 PGSPGYQGPP--GEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRP-GERGLPGPPGI 250

Query: 690 ---AGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFN----FPGNFGGSNAFGPPIPP--- 739
              AG+P  G P   G        G K     P        PG  G     GP   P   
Sbjct: 251 KGPAGIP--GFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGER 308

Query: 740 --PGLGG--------GAFG-DARPGMPSV-GNSGLPGLGLDVPGFGG--GPNNLSGPSGF 785
             PGL G        GA G D +PG P   G +G PG     PG  G  GP    G +G 
Sbjct: 309 GRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGS----PGAKGEVGPAGSPGSNGA 364

Query: 786 GG-----GPQNFGNGPGSLGGPPGFGSGPPGLGS-APGHLGGPPAFGPGPGPGPGPGPIH 839
            G     GPQ      G   GPPG    P G G   P  + G P      GP   PGP  
Sbjct: 365 PGQRGEPGPQGHAGAQGP-PGPPGINGSPGGKGEMGPAGIPGAPGLMGARGP---PGPAG 420

Query: 840 IGGPPGFASSSGKPGPTVIKVQNMP 864
             G PG    +G+PG    K +  P
Sbjct: 421 ANGAPGLRGGAGEPGKNGAKGEPGP 445



 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 95/302 (31%), Positives = 103/302 (34%), Gaps = 92/302 (30%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPNA-GLPGV-GLPSAGLPGAGLPSTGLPG--------- 679
           P  QG +G K    G+P  PG+P   G PG+ G P  G PG    S G PG         
Sbjct: 99  PNGQGPQGPK----GDPGPPGIPGRNGDPGIPGQP--GSPG----SPGPPGICESCPTGP 148

Query: 680 -------------SAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGS--KEANNGPPFNFP 724
                        S +   GL G   P AG P   G        GS       GPP   P
Sbjct: 149 QNYSPQYDSYDVKSGVAVGGLAGYPGP-AGPPGPPGPPGTSGHPGSPGSPGYQGPPGE-P 206

Query: 725 GNFGGSNAFGPP--IPPPGLGGGAFGDARPGMPSVGNSGLPGLG-----LDVPGFGG--- 774
           G  G S   GPP  I P G  G      RPG P  G  GLPG         +PGF G   
Sbjct: 207 GQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRP--GERGLPGPPGIKGPAGIPGFPGMKG 264

Query: 775 --------------------------GPNNLSGPSGFGGGPQNFGNG--PGSLG------ 800
                                     G N   GP G  G P   G    PG+ G      
Sbjct: 265 HRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDG 324

Query: 801 -----GPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIG--GPPGFASSSGKP 853
                G PG   GPPG    PG  G     GP   PG    P   G  GP G A + G P
Sbjct: 325 ARGSDGQPG-PPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPP 383

Query: 854 GP 855
           GP
Sbjct: 384 GP 385



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 85/268 (31%), Positives = 97/268 (36%), Gaps = 40/268 (14%)

Query: 631  PPAQGKKGLKMPVPGNPAVPGMPN-AGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPG 689
            P A G  G + P PG   +PG+   AG PG      G PG    S GLPG   +  G   
Sbjct: 983  PGANGLSGERGP-PGPQGLPGLAGTAGEPG----RDGNPG----SDGLPGRDGSPGGKGD 1033

Query: 690  AGMP-SAGIPSAGGEEHAFLTVG-----SKEANNGP--PFNFPGNFGGSNAFGPPIPPPG 741
             G   S G P A G       VG          +GP  P   PG  G   A GP  P   
Sbjct: 1034 RGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGD 1093

Query: 742  LG-----GGAFGDARPGMPSVGNSGLPGLGLDVPGFGG--------GPNNLSGPSGFGGG 788
             G     G A      G P  GN G PG     PG  G        GP    GP G  G 
Sbjct: 1094 KGETGERGAAGIKGHRGFP--GNPGAPGS----PGPAGQQGAIGSPGPAGPRGPVGPSGP 1147

Query: 789  PQNFGNG--PGSLGGP-PGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPG 845
            P   G    PG +G P P    G  G   +PGH G P   GP   PGP  G +      G
Sbjct: 1148 PGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAG 1207

Query: 846  FASSSGKPGPTVIKVQNMPFTVSIDEIL 873
                           + M F ++ DEI+
Sbjct: 1208 IGGEKAGGFAPYYGDEPMDFKINTDEIM 1235



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 59/164 (35%), Positives = 65/164 (39%), Gaps = 46/164 (28%)

Query: 735 PPIPPPGLGG-GAFGDARPGMPSV-GNSGLPGLGLDVPGFGGGPNNLSGPSGF----GGG 788
           P  PP G G  G  GD  PG P + G +G PG    +PG  G P +  GP G       G
Sbjct: 95  PTRPPNGQGPQGPKGD--PGPPGIPGRNGDPG----IPGQPGSPGS-PGPPGICESCPTG 147

Query: 789 PQNF-----------GNGPGSLGGPPGFGS-----GPPGLGSAPGHLGGPPAFGP----- 827
           PQN+           G   G L G PG        GPPG    PG  G P   GP     
Sbjct: 148 PQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPG 207

Query: 828 --GPGPGPGP-GPIHIGGPPGFASSSGKPG---------PTVIK 859
             GP   PGP G I   GP G    SG+PG         P  IK
Sbjct: 208 QAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIK 251



 Score = 38.5 bits (88), Expect = 0.029
 Identities = 40/145 (27%), Positives = 47/145 (32%), Gaps = 41/145 (28%)

Query: 169 PTFSSTVPSTASPMNTVPPPPIPPIPAM---PSLPPMPSIPPIPVPPPV----PTLP--- 218
           PT  +  P+   P      P  P IP     P +P  P  P  P PP +    PT P   
Sbjct: 92  PTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNY 151

Query: 219 ---------------------PVPPVPPIPPVPSVPPMTPLPPMSGMPPLNPPPVAPLPA 257
                                P P  PP PP P  P  +  P   G P    PP  P  A
Sbjct: 152 SPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGP--PGTSGHPGSPGSPGYQGPPGEPGQA 209

Query: 258 GMNGSGAPMNLNNNLNPMFLGPLNP 282
           G +G   P        P  +GP  P
Sbjct: 210 GPSGPPGP--------PGAIGPSGP 226


>gi|148470406 heterogeneous nuclear ribonucleoprotein F [Homo
           sapiens]
          Length = 415

 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 64/211 (30%), Positives = 97/211 (45%), Gaps = 38/211 (18%)

Query: 298 PINPDDLYVSVHGMPFSAMENDVRDFFHGLRVD----AVHLLKDHVGRNNGNGLVKFLSP 353
           P   +   V + G+P+S    DV++F     +      VH +    GR +G   V+  S 
Sbjct: 5   PEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSE 64

Query: 354 QDTFEALKRNRMLMIQRYVEV--SPATERQWVAAGGHITFKQNMGPSGQTHPPPQTLPRS 411
            D   ALK++R  M  RY+EV  S  TE  WV         ++ GP+             
Sbjct: 65  DDVKMALKKDRESMGHRYIEVFKSHRTEMDWVL--------KHSGPN------------- 103

Query: 412 KSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKAT 471
                     S      GF V L+GLPF    + ++ FF  L+IV + I +   P GK T
Sbjct: 104 ----------SADSANDGF-VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKIT 152

Query: 472 GEGFVEFRNEADYKAALCRHKQYMGNRFIQV 502
           GE FV+F ++   + AL +HK+ +G+R+I+V
Sbjct: 153 GEAFVQFASQELAEKALGKHKERIGHRYIEV 183



 Score = 84.3 bits (207), Expect = 5e-16
 Identities = 64/225 (28%), Positives = 110/225 (48%), Gaps = 22/225 (9%)

Query: 429 GFCVYLKGLPFEAENKHVIDFFKKLDIVEDS--IYIAYGPNGKATGEGFVEFRNEADYKA 486
           GF V L+GLP+    + V +F     I + +  ++  Y   G+ +GE FVE  +E D K 
Sbjct: 10  GFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKM 69

Query: 487 ALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQREMILNPEGDVNSAKVCA 546
           AL + ++ MG+R+I+V     K    ++D + K     S D        +G V       
Sbjct: 70  ALKKDRESMGHRYIEVF----KSHRTEMDWVLKHSGPNSADSAN-----DGFVR------ 114

Query: 547 HITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHR 606
            +  +PF  TK +++QF  G+ +  N + + VD  G+  G+A VQF +++ A K+   H+
Sbjct: 115 -LRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHK 173

Query: 607 KKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPAVPG 651
           +++  R   V   + E++R    +PP    K + +  PG    PG
Sbjct: 174 ERIGHRYIEVFKSSQEEVRSY-SDPPL---KFMSVQRPGPYDRPG 214



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 26/74 (35%), Positives = 46/74 (62%), Gaps = 2/74 (2%)

Query: 429 GFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAAL 488
           G CV+++GLP++A    + +FF  L+ V   ++I  GP+G+ TGE  VEF    +  AA+
Sbjct: 288 GHCVHMRGLPYKATENDIYNFFSPLNPVR--VHIEIGPDGRVTGEADVEFATHEEAVAAM 345

Query: 489 CRHKQYMGNRFIQV 502
            + +  M +R+I++
Sbjct: 346 SKDRANMQHRYIEL 359



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 26/89 (29%), Positives = 50/89 (56%), Gaps = 6/89 (6%)

Query: 4   VIRLQGLPIVAGTMDIRHFFSGLTIPDG--GVHIV----GGELGEAFIVFATDEDARLGM 57
           V++L+GLP      D+++F S  TI DG  GVH +    G + GEAF+   +++D ++ +
Sbjct: 12  VVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMAL 71

Query: 58  MRTGGTIKGSKVTLLLSSKTEMQNMIELS 86
            +   ++    + +  S +TEM  +++ S
Sbjct: 72  KKDRESMGHRYIEVFKSHRTEMDWVLKHS 100



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 23/72 (31%), Positives = 44/72 (61%), Gaps = 1/72 (1%)

Query: 858 IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVIDL 917
           ++++ +PF  + +EI+ FF G +++P  + L  + +G  TGEA V F S++ A  A+   
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172

Query: 918 NDRPIGSRKVKL 929
            +R IG R +++
Sbjct: 173 KER-IGHRYIEV 183



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 23/69 (33%), Positives = 38/69 (55%)

Query: 306 VSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEALKRNRM 365
           V + G+P+ A END+ +FF  L    VH+     GR  G   V+F + ++   A+ ++R 
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRA 350

Query: 366 LMIQRYVEV 374
            M  RY+E+
Sbjct: 351 NMQHRYIEL 359



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 22/82 (26%), Positives = 45/82 (54%), Gaps = 2/82 (2%)

Query: 302 DDLYVSVHGMPFSAMENDVRDFFHGLRV--DAVHLLKDHVGRNNGNGLVKFLSPQDTFEA 359
           +D +V + G+PF   + ++  FF GL +  + + L  D  G+  G   V+F S +   +A
Sbjct: 109 NDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKA 168

Query: 360 LKRNRMLMIQRYVEVSPATERQ 381
           L +++  +  RY+EV  +++ +
Sbjct: 169 LGKHKERIGHRYIEVFKSSQEE 190



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 4/81 (4%)

Query: 5   IRLQGLPIVAGTMDIRHFFSGLTIPDGGVHI----VGGELGEAFIVFATDEDARLGMMRT 60
           +RL+GLP      +I  FFSGL I   G+ +     G   GEAF+ FA+ E A   + + 
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172

Query: 61  GGTIKGSKVTLLLSSKTEMQN 81
              I    + +  SS+ E+++
Sbjct: 173 KERIGHRYIEVFKSSQEEVRS 193



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 14/85 (16%)

Query: 5   IRLQGLPIVAGTMDIRHFFSGLTI--------PDGGVHIVGGELGEAFIVFATDEDARLG 56
           + ++GLP  A   DI +FFS L          PDG V       GEA + FAT E+A   
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRV------TGEADVEFATHEEAVAA 344

Query: 57  MMRTGGTIKGSKVTLLLSSKTEMQN 81
           M +    ++   + L L+S T   N
Sbjct: 345 MSKDRANMQHRYIELFLNSTTGASN 369



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 20/78 (25%), Positives = 39/78 (50%), Gaps = 4/78 (5%)

Query: 545 CAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERL 604
           C H+  +P+  T+ D+  F    P++   VH+ +  +G+  G+A V+F   ++A  +   
Sbjct: 290 CVHMRGLPYKATENDIYNFFS--PLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSK 347

Query: 605 HRKKLNGR--EAFVHVVT 620
            R  +  R  E F++  T
Sbjct: 348 DRANMQHRYIELFLNSTT 365



 Score = 30.4 bits (67), Expect = 8.0
 Identities = 17/57 (29%), Positives = 31/57 (54%), Gaps = 2/57 (3%)

Query: 858 IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAV 914
           + ++ +P+  + ++I +FF      P  V ++    G  TGEA V F + +EA AA+
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLN--PVRVHIEIGPDGRVTGEADVEFATHEEAVAAM 345


>gi|148470404 heterogeneous nuclear ribonucleoprotein F [Homo
           sapiens]
          Length = 415

 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 64/211 (30%), Positives = 97/211 (45%), Gaps = 38/211 (18%)

Query: 298 PINPDDLYVSVHGMPFSAMENDVRDFFHGLRVD----AVHLLKDHVGRNNGNGLVKFLSP 353
           P   +   V + G+P+S    DV++F     +      VH +    GR +G   V+  S 
Sbjct: 5   PEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSE 64

Query: 354 QDTFEALKRNRMLMIQRYVEV--SPATERQWVAAGGHITFKQNMGPSGQTHPPPQTLPRS 411
            D   ALK++R  M  RY+EV  S  TE  WV         ++ GP+             
Sbjct: 65  DDVKMALKKDRESMGHRYIEVFKSHRTEMDWVL--------KHSGPN------------- 103

Query: 412 KSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKAT 471
                     S      GF V L+GLPF    + ++ FF  L+IV + I +   P GK T
Sbjct: 104 ----------SADSANDGF-VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKIT 152

Query: 472 GEGFVEFRNEADYKAALCRHKQYMGNRFIQV 502
           GE FV+F ++   + AL +HK+ +G+R+I+V
Sbjct: 153 GEAFVQFASQELAEKALGKHKERIGHRYIEV 183



 Score = 84.3 bits (207), Expect = 5e-16
 Identities = 64/225 (28%), Positives = 110/225 (48%), Gaps = 22/225 (9%)

Query: 429 GFCVYLKGLPFEAENKHVIDFFKKLDIVEDS--IYIAYGPNGKATGEGFVEFRNEADYKA 486
           GF V L+GLP+    + V +F     I + +  ++  Y   G+ +GE FVE  +E D K 
Sbjct: 10  GFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKM 69

Query: 487 ALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQREMILNPEGDVNSAKVCA 546
           AL + ++ MG+R+I+V     K    ++D + K     S D        +G V       
Sbjct: 70  ALKKDRESMGHRYIEVF----KSHRTEMDWVLKHSGPNSADSAN-----DGFVR------ 114

Query: 547 HITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHR 606
            +  +PF  TK +++QF  G+ +  N + + VD  G+  G+A VQF +++ A K+   H+
Sbjct: 115 -LRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHK 173

Query: 607 KKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPAVPG 651
           +++  R   V   + E++R    +PP    K + +  PG    PG
Sbjct: 174 ERIGHRYIEVFKSSQEEVRSY-SDPPL---KFMSVQRPGPYDRPG 214



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 26/74 (35%), Positives = 46/74 (62%), Gaps = 2/74 (2%)

Query: 429 GFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAAL 488
           G CV+++GLP++A    + +FF  L+ V   ++I  GP+G+ TGE  VEF    +  AA+
Sbjct: 288 GHCVHMRGLPYKATENDIYNFFSPLNPVR--VHIEIGPDGRVTGEADVEFATHEEAVAAM 345

Query: 489 CRHKQYMGNRFIQV 502
            + +  M +R+I++
Sbjct: 346 SKDRANMQHRYIEL 359



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 26/89 (29%), Positives = 50/89 (56%), Gaps = 6/89 (6%)

Query: 4   VIRLQGLPIVAGTMDIRHFFSGLTIPDG--GVHIV----GGELGEAFIVFATDEDARLGM 57
           V++L+GLP      D+++F S  TI DG  GVH +    G + GEAF+   +++D ++ +
Sbjct: 12  VVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMAL 71

Query: 58  MRTGGTIKGSKVTLLLSSKTEMQNMIELS 86
            +   ++    + +  S +TEM  +++ S
Sbjct: 72  KKDRESMGHRYIEVFKSHRTEMDWVLKHS 100



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 23/72 (31%), Positives = 44/72 (61%), Gaps = 1/72 (1%)

Query: 858 IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVIDL 917
           ++++ +PF  + +EI+ FF G +++P  + L  + +G  TGEA V F S++ A  A+   
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172

Query: 918 NDRPIGSRKVKL 929
            +R IG R +++
Sbjct: 173 KER-IGHRYIEV 183



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 23/69 (33%), Positives = 38/69 (55%)

Query: 306 VSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEALKRNRM 365
           V + G+P+ A END+ +FF  L    VH+     GR  G   V+F + ++   A+ ++R 
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRA 350

Query: 366 LMIQRYVEV 374
            M  RY+E+
Sbjct: 351 NMQHRYIEL 359



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 22/82 (26%), Positives = 45/82 (54%), Gaps = 2/82 (2%)

Query: 302 DDLYVSVHGMPFSAMENDVRDFFHGLRV--DAVHLLKDHVGRNNGNGLVKFLSPQDTFEA 359
           +D +V + G+PF   + ++  FF GL +  + + L  D  G+  G   V+F S +   +A
Sbjct: 109 NDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKA 168

Query: 360 LKRNRMLMIQRYVEVSPATERQ 381
           L +++  +  RY+EV  +++ +
Sbjct: 169 LGKHKERIGHRYIEVFKSSQEE 190



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 4/81 (4%)

Query: 5   IRLQGLPIVAGTMDIRHFFSGLTIPDGGVHI----VGGELGEAFIVFATDEDARLGMMRT 60
           +RL+GLP      +I  FFSGL I   G+ +     G   GEAF+ FA+ E A   + + 
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172

Query: 61  GGTIKGSKVTLLLSSKTEMQN 81
              I    + +  SS+ E+++
Sbjct: 173 KERIGHRYIEVFKSSQEEVRS 193



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 14/85 (16%)

Query: 5   IRLQGLPIVAGTMDIRHFFSGLTI--------PDGGVHIVGGELGEAFIVFATDEDARLG 56
           + ++GLP  A   DI +FFS L          PDG V       GEA + FAT E+A   
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRV------TGEADVEFATHEEAVAA 344

Query: 57  MMRTGGTIKGSKVTLLLSSKTEMQN 81
           M +    ++   + L L+S T   N
Sbjct: 345 MSKDRANMQHRYIELFLNSTTGASN 369



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 20/78 (25%), Positives = 39/78 (50%), Gaps = 4/78 (5%)

Query: 545 CAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERL 604
           C H+  +P+  T+ D+  F    P++   VH+ +  +G+  G+A V+F   ++A  +   
Sbjct: 290 CVHMRGLPYKATENDIYNFFS--PLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSK 347

Query: 605 HRKKLNGR--EAFVHVVT 620
            R  +  R  E F++  T
Sbjct: 348 DRANMQHRYIELFLNSTT 365



 Score = 30.4 bits (67), Expect = 8.0
 Identities = 17/57 (29%), Positives = 31/57 (54%), Gaps = 2/57 (3%)

Query: 858 IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAV 914
           + ++ +P+  + ++I +FF      P  V ++    G  TGEA V F + +EA AA+
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLN--PVRVHIEIGPDGRVTGEADVEFATHEEAVAAM 345


>gi|148470402 heterogeneous nuclear ribonucleoprotein F [Homo
           sapiens]
          Length = 415

 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 64/211 (30%), Positives = 97/211 (45%), Gaps = 38/211 (18%)

Query: 298 PINPDDLYVSVHGMPFSAMENDVRDFFHGLRVD----AVHLLKDHVGRNNGNGLVKFLSP 353
           P   +   V + G+P+S    DV++F     +      VH +    GR +G   V+  S 
Sbjct: 5   PEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSE 64

Query: 354 QDTFEALKRNRMLMIQRYVEV--SPATERQWVAAGGHITFKQNMGPSGQTHPPPQTLPRS 411
            D   ALK++R  M  RY+EV  S  TE  WV         ++ GP+             
Sbjct: 65  DDVKMALKKDRESMGHRYIEVFKSHRTEMDWVL--------KHSGPN------------- 103

Query: 412 KSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKAT 471
                     S      GF V L+GLPF    + ++ FF  L+IV + I +   P GK T
Sbjct: 104 ----------SADSANDGF-VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKIT 152

Query: 472 GEGFVEFRNEADYKAALCRHKQYMGNRFIQV 502
           GE FV+F ++   + AL +HK+ +G+R+I+V
Sbjct: 153 GEAFVQFASQELAEKALGKHKERIGHRYIEV 183



 Score = 84.3 bits (207), Expect = 5e-16
 Identities = 64/225 (28%), Positives = 110/225 (48%), Gaps = 22/225 (9%)

Query: 429 GFCVYLKGLPFEAENKHVIDFFKKLDIVEDS--IYIAYGPNGKATGEGFVEFRNEADYKA 486
           GF V L+GLP+    + V +F     I + +  ++  Y   G+ +GE FVE  +E D K 
Sbjct: 10  GFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKM 69

Query: 487 ALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQREMILNPEGDVNSAKVCA 546
           AL + ++ MG+R+I+V     K    ++D + K     S D        +G V       
Sbjct: 70  ALKKDRESMGHRYIEVF----KSHRTEMDWVLKHSGPNSADSAN-----DGFVR------ 114

Query: 547 HITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHR 606
            +  +PF  TK +++QF  G+ +  N + + VD  G+  G+A VQF +++ A K+   H+
Sbjct: 115 -LRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHK 173

Query: 607 KKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPAVPG 651
           +++  R   V   + E++R    +PP    K + +  PG    PG
Sbjct: 174 ERIGHRYIEVFKSSQEEVRSY-SDPPL---KFMSVQRPGPYDRPG 214



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 26/74 (35%), Positives = 46/74 (62%), Gaps = 2/74 (2%)

Query: 429 GFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAAL 488
           G CV+++GLP++A    + +FF  L+ V   ++I  GP+G+ TGE  VEF    +  AA+
Sbjct: 288 GHCVHMRGLPYKATENDIYNFFSPLNPVR--VHIEIGPDGRVTGEADVEFATHEEAVAAM 345

Query: 489 CRHKQYMGNRFIQV 502
            + +  M +R+I++
Sbjct: 346 SKDRANMQHRYIEL 359



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 26/89 (29%), Positives = 50/89 (56%), Gaps = 6/89 (6%)

Query: 4   VIRLQGLPIVAGTMDIRHFFSGLTIPDG--GVHIV----GGELGEAFIVFATDEDARLGM 57
           V++L+GLP      D+++F S  TI DG  GVH +    G + GEAF+   +++D ++ +
Sbjct: 12  VVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMAL 71

Query: 58  MRTGGTIKGSKVTLLLSSKTEMQNMIELS 86
            +   ++    + +  S +TEM  +++ S
Sbjct: 72  KKDRESMGHRYIEVFKSHRTEMDWVLKHS 100



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 23/72 (31%), Positives = 44/72 (61%), Gaps = 1/72 (1%)

Query: 858 IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVIDL 917
           ++++ +PF  + +EI+ FF G +++P  + L  + +G  TGEA V F S++ A  A+   
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172

Query: 918 NDRPIGSRKVKL 929
            +R IG R +++
Sbjct: 173 KER-IGHRYIEV 183



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 23/69 (33%), Positives = 38/69 (55%)

Query: 306 VSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEALKRNRM 365
           V + G+P+ A END+ +FF  L    VH+     GR  G   V+F + ++   A+ ++R 
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRA 350

Query: 366 LMIQRYVEV 374
            M  RY+E+
Sbjct: 351 NMQHRYIEL 359



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 22/82 (26%), Positives = 45/82 (54%), Gaps = 2/82 (2%)

Query: 302 DDLYVSVHGMPFSAMENDVRDFFHGLRV--DAVHLLKDHVGRNNGNGLVKFLSPQDTFEA 359
           +D +V + G+PF   + ++  FF GL +  + + L  D  G+  G   V+F S +   +A
Sbjct: 109 NDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKA 168

Query: 360 LKRNRMLMIQRYVEVSPATERQ 381
           L +++  +  RY+EV  +++ +
Sbjct: 169 LGKHKERIGHRYIEVFKSSQEE 190



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 4/81 (4%)

Query: 5   IRLQGLPIVAGTMDIRHFFSGLTIPDGGVHI----VGGELGEAFIVFATDEDARLGMMRT 60
           +RL+GLP      +I  FFSGL I   G+ +     G   GEAF+ FA+ E A   + + 
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172

Query: 61  GGTIKGSKVTLLLSSKTEMQN 81
              I    + +  SS+ E+++
Sbjct: 173 KERIGHRYIEVFKSSQEEVRS 193



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 14/85 (16%)

Query: 5   IRLQGLPIVAGTMDIRHFFSGLTI--------PDGGVHIVGGELGEAFIVFATDEDARLG 56
           + ++GLP  A   DI +FFS L          PDG V       GEA + FAT E+A   
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRV------TGEADVEFATHEEAVAA 344

Query: 57  MMRTGGTIKGSKVTLLLSSKTEMQN 81
           M +    ++   + L L+S T   N
Sbjct: 345 MSKDRANMQHRYIELFLNSTTGASN 369



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 20/78 (25%), Positives = 39/78 (50%), Gaps = 4/78 (5%)

Query: 545 CAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERL 604
           C H+  +P+  T+ D+  F    P++   VH+ +  +G+  G+A V+F   ++A  +   
Sbjct: 290 CVHMRGLPYKATENDIYNFFS--PLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSK 347

Query: 605 HRKKLNGR--EAFVHVVT 620
            R  +  R  E F++  T
Sbjct: 348 DRANMQHRYIELFLNSTT 365



 Score = 30.4 bits (67), Expect = 8.0
 Identities = 17/57 (29%), Positives = 31/57 (54%), Gaps = 2/57 (3%)

Query: 858 IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAV 914
           + ++ +P+  + ++I +FF      P  V ++    G  TGEA V F + +EA AA+
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLN--PVRVHIEIGPDGRVTGEADVEFATHEEAVAAM 345


>gi|148470400 heterogeneous nuclear ribonucleoprotein F [Homo
           sapiens]
          Length = 415

 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 64/211 (30%), Positives = 97/211 (45%), Gaps = 38/211 (18%)

Query: 298 PINPDDLYVSVHGMPFSAMENDVRDFFHGLRVD----AVHLLKDHVGRNNGNGLVKFLSP 353
           P   +   V + G+P+S    DV++F     +      VH +    GR +G   V+  S 
Sbjct: 5   PEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSE 64

Query: 354 QDTFEALKRNRMLMIQRYVEV--SPATERQWVAAGGHITFKQNMGPSGQTHPPPQTLPRS 411
            D   ALK++R  M  RY+EV  S  TE  WV         ++ GP+             
Sbjct: 65  DDVKMALKKDRESMGHRYIEVFKSHRTEMDWVL--------KHSGPN------------- 103

Query: 412 KSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKAT 471
                     S      GF V L+GLPF    + ++ FF  L+IV + I +   P GK T
Sbjct: 104 ----------SADSANDGF-VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKIT 152

Query: 472 GEGFVEFRNEADYKAALCRHKQYMGNRFIQV 502
           GE FV+F ++   + AL +HK+ +G+R+I+V
Sbjct: 153 GEAFVQFASQELAEKALGKHKERIGHRYIEV 183



 Score = 84.3 bits (207), Expect = 5e-16
 Identities = 64/225 (28%), Positives = 110/225 (48%), Gaps = 22/225 (9%)

Query: 429 GFCVYLKGLPFEAENKHVIDFFKKLDIVEDS--IYIAYGPNGKATGEGFVEFRNEADYKA 486
           GF V L+GLP+    + V +F     I + +  ++  Y   G+ +GE FVE  +E D K 
Sbjct: 10  GFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKM 69

Query: 487 ALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQREMILNPEGDVNSAKVCA 546
           AL + ++ MG+R+I+V     K    ++D + K     S D        +G V       
Sbjct: 70  ALKKDRESMGHRYIEVF----KSHRTEMDWVLKHSGPNSADSAN-----DGFVR------ 114

Query: 547 HITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHR 606
            +  +PF  TK +++QF  G+ +  N + + VD  G+  G+A VQF +++ A K+   H+
Sbjct: 115 -LRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHK 173

Query: 607 KKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPAVPG 651
           +++  R   V   + E++R    +PP    K + +  PG    PG
Sbjct: 174 ERIGHRYIEVFKSSQEEVRSY-SDPPL---KFMSVQRPGPYDRPG 214



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 26/74 (35%), Positives = 46/74 (62%), Gaps = 2/74 (2%)

Query: 429 GFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAAL 488
           G CV+++GLP++A    + +FF  L+ V   ++I  GP+G+ TGE  VEF    +  AA+
Sbjct: 288 GHCVHMRGLPYKATENDIYNFFSPLNPVR--VHIEIGPDGRVTGEADVEFATHEEAVAAM 345

Query: 489 CRHKQYMGNRFIQV 502
            + +  M +R+I++
Sbjct: 346 SKDRANMQHRYIEL 359



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 26/89 (29%), Positives = 50/89 (56%), Gaps = 6/89 (6%)

Query: 4   VIRLQGLPIVAGTMDIRHFFSGLTIPDG--GVHIV----GGELGEAFIVFATDEDARLGM 57
           V++L+GLP      D+++F S  TI DG  GVH +    G + GEAF+   +++D ++ +
Sbjct: 12  VVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMAL 71

Query: 58  MRTGGTIKGSKVTLLLSSKTEMQNMIELS 86
            +   ++    + +  S +TEM  +++ S
Sbjct: 72  KKDRESMGHRYIEVFKSHRTEMDWVLKHS 100



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 23/72 (31%), Positives = 44/72 (61%), Gaps = 1/72 (1%)

Query: 858 IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVIDL 917
           ++++ +PF  + +EI+ FF G +++P  + L  + +G  TGEA V F S++ A  A+   
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172

Query: 918 NDRPIGSRKVKL 929
            +R IG R +++
Sbjct: 173 KER-IGHRYIEV 183



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 23/69 (33%), Positives = 38/69 (55%)

Query: 306 VSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEALKRNRM 365
           V + G+P+ A END+ +FF  L    VH+     GR  G   V+F + ++   A+ ++R 
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRA 350

Query: 366 LMIQRYVEV 374
            M  RY+E+
Sbjct: 351 NMQHRYIEL 359



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 22/82 (26%), Positives = 45/82 (54%), Gaps = 2/82 (2%)

Query: 302 DDLYVSVHGMPFSAMENDVRDFFHGLRV--DAVHLLKDHVGRNNGNGLVKFLSPQDTFEA 359
           +D +V + G+PF   + ++  FF GL +  + + L  D  G+  G   V+F S +   +A
Sbjct: 109 NDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKA 168

Query: 360 LKRNRMLMIQRYVEVSPATERQ 381
           L +++  +  RY+EV  +++ +
Sbjct: 169 LGKHKERIGHRYIEVFKSSQEE 190



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 4/81 (4%)

Query: 5   IRLQGLPIVAGTMDIRHFFSGLTIPDGGVHI----VGGELGEAFIVFATDEDARLGMMRT 60
           +RL+GLP      +I  FFSGL I   G+ +     G   GEAF+ FA+ E A   + + 
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172

Query: 61  GGTIKGSKVTLLLSSKTEMQN 81
              I    + +  SS+ E+++
Sbjct: 173 KERIGHRYIEVFKSSQEEVRS 193



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 14/85 (16%)

Query: 5   IRLQGLPIVAGTMDIRHFFSGLTI--------PDGGVHIVGGELGEAFIVFATDEDARLG 56
           + ++GLP  A   DI +FFS L          PDG V       GEA + FAT E+A   
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRV------TGEADVEFATHEEAVAA 344

Query: 57  MMRTGGTIKGSKVTLLLSSKTEMQN 81
           M +    ++   + L L+S T   N
Sbjct: 345 MSKDRANMQHRYIELFLNSTTGASN 369



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 20/78 (25%), Positives = 39/78 (50%), Gaps = 4/78 (5%)

Query: 545 CAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERL 604
           C H+  +P+  T+ D+  F    P++   VH+ +  +G+  G+A V+F   ++A  +   
Sbjct: 290 CVHMRGLPYKATENDIYNFFS--PLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSK 347

Query: 605 HRKKLNGR--EAFVHVVT 620
            R  +  R  E F++  T
Sbjct: 348 DRANMQHRYIELFLNSTT 365



 Score = 30.4 bits (67), Expect = 8.0
 Identities = 17/57 (29%), Positives = 31/57 (54%), Gaps = 2/57 (3%)

Query: 858 IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAV 914
           + ++ +P+  + ++I +FF      P  V ++    G  TGEA V F + +EA AA+
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLN--PVRVHIEIGPDGRVTGEADVEFATHEEAVAAM 345


>gi|148470397 heterogeneous nuclear ribonucleoprotein F [Homo
           sapiens]
          Length = 415

 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 64/211 (30%), Positives = 97/211 (45%), Gaps = 38/211 (18%)

Query: 298 PINPDDLYVSVHGMPFSAMENDVRDFFHGLRVD----AVHLLKDHVGRNNGNGLVKFLSP 353
           P   +   V + G+P+S    DV++F     +      VH +    GR +G   V+  S 
Sbjct: 5   PEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSE 64

Query: 354 QDTFEALKRNRMLMIQRYVEV--SPATERQWVAAGGHITFKQNMGPSGQTHPPPQTLPRS 411
            D   ALK++R  M  RY+EV  S  TE  WV         ++ GP+             
Sbjct: 65  DDVKMALKKDRESMGHRYIEVFKSHRTEMDWVL--------KHSGPN------------- 103

Query: 412 KSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKAT 471
                     S      GF V L+GLPF    + ++ FF  L+IV + I +   P GK T
Sbjct: 104 ----------SADSANDGF-VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKIT 152

Query: 472 GEGFVEFRNEADYKAALCRHKQYMGNRFIQV 502
           GE FV+F ++   + AL +HK+ +G+R+I+V
Sbjct: 153 GEAFVQFASQELAEKALGKHKERIGHRYIEV 183



 Score = 84.3 bits (207), Expect = 5e-16
 Identities = 64/225 (28%), Positives = 110/225 (48%), Gaps = 22/225 (9%)

Query: 429 GFCVYLKGLPFEAENKHVIDFFKKLDIVEDS--IYIAYGPNGKATGEGFVEFRNEADYKA 486
           GF V L+GLP+    + V +F     I + +  ++  Y   G+ +GE FVE  +E D K 
Sbjct: 10  GFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKM 69

Query: 487 ALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQREMILNPEGDVNSAKVCA 546
           AL + ++ MG+R+I+V     K    ++D + K     S D        +G V       
Sbjct: 70  ALKKDRESMGHRYIEVF----KSHRTEMDWVLKHSGPNSADSAN-----DGFVR------ 114

Query: 547 HITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHR 606
            +  +PF  TK +++QF  G+ +  N + + VD  G+  G+A VQF +++ A K+   H+
Sbjct: 115 -LRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHK 173

Query: 607 KKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPAVPG 651
           +++  R   V   + E++R    +PP    K + +  PG    PG
Sbjct: 174 ERIGHRYIEVFKSSQEEVRSY-SDPPL---KFMSVQRPGPYDRPG 214



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 26/74 (35%), Positives = 46/74 (62%), Gaps = 2/74 (2%)

Query: 429 GFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAAL 488
           G CV+++GLP++A    + +FF  L+ V   ++I  GP+G+ TGE  VEF    +  AA+
Sbjct: 288 GHCVHMRGLPYKATENDIYNFFSPLNPVR--VHIEIGPDGRVTGEADVEFATHEEAVAAM 345

Query: 489 CRHKQYMGNRFIQV 502
            + +  M +R+I++
Sbjct: 346 SKDRANMQHRYIEL 359



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 26/89 (29%), Positives = 50/89 (56%), Gaps = 6/89 (6%)

Query: 4   VIRLQGLPIVAGTMDIRHFFSGLTIPDG--GVHIV----GGELGEAFIVFATDEDARLGM 57
           V++L+GLP      D+++F S  TI DG  GVH +    G + GEAF+   +++D ++ +
Sbjct: 12  VVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMAL 71

Query: 58  MRTGGTIKGSKVTLLLSSKTEMQNMIELS 86
            +   ++    + +  S +TEM  +++ S
Sbjct: 72  KKDRESMGHRYIEVFKSHRTEMDWVLKHS 100



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 23/72 (31%), Positives = 44/72 (61%), Gaps = 1/72 (1%)

Query: 858 IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVIDL 917
           ++++ +PF  + +EI+ FF G +++P  + L  + +G  TGEA V F S++ A  A+   
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172

Query: 918 NDRPIGSRKVKL 929
            +R IG R +++
Sbjct: 173 KER-IGHRYIEV 183



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 23/69 (33%), Positives = 38/69 (55%)

Query: 306 VSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEALKRNRM 365
           V + G+P+ A END+ +FF  L    VH+     GR  G   V+F + ++   A+ ++R 
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRA 350

Query: 366 LMIQRYVEV 374
            M  RY+E+
Sbjct: 351 NMQHRYIEL 359



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 22/82 (26%), Positives = 45/82 (54%), Gaps = 2/82 (2%)

Query: 302 DDLYVSVHGMPFSAMENDVRDFFHGLRV--DAVHLLKDHVGRNNGNGLVKFLSPQDTFEA 359
           +D +V + G+PF   + ++  FF GL +  + + L  D  G+  G   V+F S +   +A
Sbjct: 109 NDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKA 168

Query: 360 LKRNRMLMIQRYVEVSPATERQ 381
           L +++  +  RY+EV  +++ +
Sbjct: 169 LGKHKERIGHRYIEVFKSSQEE 190



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 4/81 (4%)

Query: 5   IRLQGLPIVAGTMDIRHFFSGLTIPDGGVHI----VGGELGEAFIVFATDEDARLGMMRT 60
           +RL+GLP      +I  FFSGL I   G+ +     G   GEAF+ FA+ E A   + + 
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172

Query: 61  GGTIKGSKVTLLLSSKTEMQN 81
              I    + +  SS+ E+++
Sbjct: 173 KERIGHRYIEVFKSSQEEVRS 193



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 14/85 (16%)

Query: 5   IRLQGLPIVAGTMDIRHFFSGLTI--------PDGGVHIVGGELGEAFIVFATDEDARLG 56
           + ++GLP  A   DI +FFS L          PDG V       GEA + FAT E+A   
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRV------TGEADVEFATHEEAVAA 344

Query: 57  MMRTGGTIKGSKVTLLLSSKTEMQN 81
           M +    ++   + L L+S T   N
Sbjct: 345 MSKDRANMQHRYIELFLNSTTGASN 369



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 20/78 (25%), Positives = 39/78 (50%), Gaps = 4/78 (5%)

Query: 545 CAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERL 604
           C H+  +P+  T+ D+  F    P++   VH+ +  +G+  G+A V+F   ++A  +   
Sbjct: 290 CVHMRGLPYKATENDIYNFFS--PLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSK 347

Query: 605 HRKKLNGR--EAFVHVVT 620
            R  +  R  E F++  T
Sbjct: 348 DRANMQHRYIELFLNSTT 365



 Score = 30.4 bits (67), Expect = 8.0
 Identities = 17/57 (29%), Positives = 31/57 (54%), Gaps = 2/57 (3%)

Query: 858 IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAV 914
           + ++ +P+  + ++I +FF      P  V ++    G  TGEA V F + +EA AA+
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLN--PVRVHIEIGPDGRVTGEADVEFATHEEAVAAM 345


>gi|4826760 heterogeneous nuclear ribonucleoprotein F [Homo sapiens]
          Length = 415

 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 64/211 (30%), Positives = 97/211 (45%), Gaps = 38/211 (18%)

Query: 298 PINPDDLYVSVHGMPFSAMENDVRDFFHGLRVD----AVHLLKDHVGRNNGNGLVKFLSP 353
           P   +   V + G+P+S    DV++F     +      VH +    GR +G   V+  S 
Sbjct: 5   PEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSE 64

Query: 354 QDTFEALKRNRMLMIQRYVEV--SPATERQWVAAGGHITFKQNMGPSGQTHPPPQTLPRS 411
            D   ALK++R  M  RY+EV  S  TE  WV         ++ GP+             
Sbjct: 65  DDVKMALKKDRESMGHRYIEVFKSHRTEMDWVL--------KHSGPN------------- 103

Query: 412 KSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKAT 471
                     S      GF V L+GLPF    + ++ FF  L+IV + I +   P GK T
Sbjct: 104 ----------SADSANDGF-VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKIT 152

Query: 472 GEGFVEFRNEADYKAALCRHKQYMGNRFIQV 502
           GE FV+F ++   + AL +HK+ +G+R+I+V
Sbjct: 153 GEAFVQFASQELAEKALGKHKERIGHRYIEV 183



 Score = 84.3 bits (207), Expect = 5e-16
 Identities = 64/225 (28%), Positives = 110/225 (48%), Gaps = 22/225 (9%)

Query: 429 GFCVYLKGLPFEAENKHVIDFFKKLDIVEDS--IYIAYGPNGKATGEGFVEFRNEADYKA 486
           GF V L+GLP+    + V +F     I + +  ++  Y   G+ +GE FVE  +E D K 
Sbjct: 10  GFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKM 69

Query: 487 ALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQREMILNPEGDVNSAKVCA 546
           AL + ++ MG+R+I+V     K    ++D + K     S D        +G V       
Sbjct: 70  ALKKDRESMGHRYIEVF----KSHRTEMDWVLKHSGPNSADSAN-----DGFVR------ 114

Query: 547 HITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHR 606
            +  +PF  TK +++QF  G+ +  N + + VD  G+  G+A VQF +++ A K+   H+
Sbjct: 115 -LRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHK 173

Query: 607 KKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPAVPG 651
           +++  R   V   + E++R    +PP    K + +  PG    PG
Sbjct: 174 ERIGHRYIEVFKSSQEEVRSY-SDPPL---KFMSVQRPGPYDRPG 214



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 26/74 (35%), Positives = 46/74 (62%), Gaps = 2/74 (2%)

Query: 429 GFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAAL 488
           G CV+++GLP++A    + +FF  L+ V   ++I  GP+G+ TGE  VEF    +  AA+
Sbjct: 288 GHCVHMRGLPYKATENDIYNFFSPLNPVR--VHIEIGPDGRVTGEADVEFATHEEAVAAM 345

Query: 489 CRHKQYMGNRFIQV 502
            + +  M +R+I++
Sbjct: 346 SKDRANMQHRYIEL 359



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 26/89 (29%), Positives = 50/89 (56%), Gaps = 6/89 (6%)

Query: 4   VIRLQGLPIVAGTMDIRHFFSGLTIPDG--GVHIV----GGELGEAFIVFATDEDARLGM 57
           V++L+GLP      D+++F S  TI DG  GVH +    G + GEAF+   +++D ++ +
Sbjct: 12  VVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMAL 71

Query: 58  MRTGGTIKGSKVTLLLSSKTEMQNMIELS 86
            +   ++    + +  S +TEM  +++ S
Sbjct: 72  KKDRESMGHRYIEVFKSHRTEMDWVLKHS 100



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 23/72 (31%), Positives = 44/72 (61%), Gaps = 1/72 (1%)

Query: 858 IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVIDL 917
           ++++ +PF  + +EI+ FF G +++P  + L  + +G  TGEA V F S++ A  A+   
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172

Query: 918 NDRPIGSRKVKL 929
            +R IG R +++
Sbjct: 173 KER-IGHRYIEV 183



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 23/69 (33%), Positives = 38/69 (55%)

Query: 306 VSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEALKRNRM 365
           V + G+P+ A END+ +FF  L    VH+     GR  G   V+F + ++   A+ ++R 
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRA 350

Query: 366 LMIQRYVEV 374
            M  RY+E+
Sbjct: 351 NMQHRYIEL 359



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 22/82 (26%), Positives = 45/82 (54%), Gaps = 2/82 (2%)

Query: 302 DDLYVSVHGMPFSAMENDVRDFFHGLRV--DAVHLLKDHVGRNNGNGLVKFLSPQDTFEA 359
           +D +V + G+PF   + ++  FF GL +  + + L  D  G+  G   V+F S +   +A
Sbjct: 109 NDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKA 168

Query: 360 LKRNRMLMIQRYVEVSPATERQ 381
           L +++  +  RY+EV  +++ +
Sbjct: 169 LGKHKERIGHRYIEVFKSSQEE 190



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 4/81 (4%)

Query: 5   IRLQGLPIVAGTMDIRHFFSGLTIPDGGVHI----VGGELGEAFIVFATDEDARLGMMRT 60
           +RL+GLP      +I  FFSGL I   G+ +     G   GEAF+ FA+ E A   + + 
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172

Query: 61  GGTIKGSKVTLLLSSKTEMQN 81
              I    + +  SS+ E+++
Sbjct: 173 KERIGHRYIEVFKSSQEEVRS 193



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 14/85 (16%)

Query: 5   IRLQGLPIVAGTMDIRHFFSGLTI--------PDGGVHIVGGELGEAFIVFATDEDARLG 56
           + ++GLP  A   DI +FFS L          PDG V       GEA + FAT E+A   
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRV------TGEADVEFATHEEAVAA 344

Query: 57  MMRTGGTIKGSKVTLLLSSKTEMQN 81
           M +    ++   + L L+S T   N
Sbjct: 345 MSKDRANMQHRYIELFLNSTTGASN 369



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 20/78 (25%), Positives = 39/78 (50%), Gaps = 4/78 (5%)

Query: 545 CAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERL 604
           C H+  +P+  T+ D+  F    P++   VH+ +  +G+  G+A V+F   ++A  +   
Sbjct: 290 CVHMRGLPYKATENDIYNFFS--PLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSK 347

Query: 605 HRKKLNGR--EAFVHVVT 620
            R  +  R  E F++  T
Sbjct: 348 DRANMQHRYIELFLNSTT 365



 Score = 30.4 bits (67), Expect = 8.0
 Identities = 17/57 (29%), Positives = 31/57 (54%), Gaps = 2/57 (3%)

Query: 858 IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAV 914
           + ++ +P+  + ++I +FF      P  V ++    G  TGEA V F + +EA AA+
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLN--PVRVHIEIGPDGRVTGEADVEFATHEEAVAAM 345


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 85/230 (36%), Positives = 98/230 (42%), Gaps = 28/230 (12%)

Query: 634 QGKKGLKMP--VPGNPAVPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPGAG 691
           QG +G + P  V G P  PG   A  P     + G PGA   + G PG A  + G PGA 
Sbjct: 358 QGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAK-GANGAPGIA-GAPGFPGAR 415

Query: 692 MPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIP-----PPGLGGGA 746
            PS G    GG           + N+G P   PG+ G + A G P P     PPG  G  
Sbjct: 416 GPS-GPQGPGGPP-------GPKGNSGEP-GAPGSKGDTGAKGEPGPVGVQGPPGPAGEE 466

Query: 747 FGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFG-GGPQNFGNGPGSLGGPPGF 805
                 G P  G +GLPG     PG  GGP +   P   G  GP+      GS G  P  
Sbjct: 467 GKRGARGEP--GPTGLPG----PPGERGGPGSRGFPGADGVAGPKGPAGERGSPG--PAG 518

Query: 806 GSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGP 855
             G PG    PG  G P A G    PG  PGP    GPPG A   G+PGP
Sbjct: 519 PKGSPGEAGRPGEAGLPGAKGLTGSPG-SPGPDGKTGPPGPAGQDGRPGP 567



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 97/285 (34%), Positives = 110/285 (38%), Gaps = 68/285 (23%)

Query: 628 EKNPPA-QGKKGLKMPVPGNPAVPGMPN----AGLPGVGLPSAGLPGAGLPST----GLP 678
           E+ PP  QG +GL    PG   +PGM      +GL G    +      G P +    G P
Sbjct: 243 ERGPPGPQGARGL----PGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAP 298

Query: 679 GSAITSAGLPGA-GMPSAGIPS-AGGEEHAFLTVGSKEANN--GPPFNFPGNFGGSNAFG 734
           G  +   GLPG  G P A  P+ A G + A    G        GPP  FPG  G     G
Sbjct: 299 GQ-MGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPP-GFPGAVGAKGEAG 356

Query: 735 PPIP--------------PPGLGGGAFGDARPGMP----SVGNSGLPGLGLDVPGFGG-- 774
           P  P              PPG  G A     PG      + G +G PG+    PGF G  
Sbjct: 357 PQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIA-GAPGFPGAR 415

Query: 775 GPNNLSGPSGFGGGPQNFGNG-----PGSLG--------GPPGFGSGPPGLGSAPGHLG- 820
           GP   SGP G GG P   GN      PGS G        GP G   GPPG     G  G 
Sbjct: 416 GP---SGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGV-QGPPGPAGEEGKRGA 471

Query: 821 ----------GPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGP 855
                     GPP    GPG    PG   + GP G A   G PGP
Sbjct: 472 RGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGP 516



 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 87/253 (34%), Positives = 100/253 (39%), Gaps = 54/253 (21%)

Query: 635 GKKGLKMPVPGNPAVPGMPN-AGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMP 693
           G++G + P  G+P   G+P  AG PG     AG PG      G+PG     A  P     
Sbjct: 629 GERGEQGPA-GSPGFQGLPGPAGPPG----EAGKPG----EQGVPGDL--GAPGPSGARG 677

Query: 694 SAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPP-----PGLGG---- 744
             G P   G +      G + AN  P     GN G     G P  P     PGL G    
Sbjct: 678 ERGFPGERGVQGPPGPAGPRGANGAP-----GNDGAKGDAGAPGAPGSQGAPGLQGMPGE 732

Query: 745 ----------GAFGDARP----GMPSVGNSGLPGLG--LDVPGFGGGPNNL--SGPSGFG 786
                     G  GDA P    G P  G  G+ GL   +  PG  G P +   SGPSG  
Sbjct: 733 RGAAGLPGPKGDRGDAGPKGADGSP--GKDGVRGLTGPIGPPGPAGAPGDKGESGPSG-P 789

Query: 787 GGPQNFGNGPGSLG-----GPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIG 841
            GP      PG  G     GP GF +GPPG    PG  G P   G     GP PGP    
Sbjct: 790 AGPTGARGAPGDRGEPGPPGPAGF-AGPPGADGQPGAKGEPGDAGAKGDAGP-PGPAGPA 847

Query: 842 GPPGFASSSGKPG 854
           GPPG   + G PG
Sbjct: 848 GPPGPIGNVGAPG 860



 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 84/252 (33%), Positives = 96/252 (38%), Gaps = 48/252 (19%)

Query: 635 GKKGLKMPV--PGNPAVPGMPNAGLPGVGLPSA--GLPGAG-----LPSTGLPGSAITSA 685
           G +G + P   PG   +PG P  GLPG   P    G PG G       S G    +    
Sbjct: 118 GPRGPRGPAGPPGRDGIPGQP--GLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGI 175

Query: 686 GLPGAGMPSA--GIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGP--PIPPPG 741
            +PG   PS   G+P   G           +   GPP   PG  G S   GP  P  PPG
Sbjct: 176 SVPGPMGPSGPRGLPGPPG-------APGPQGFQGPP-GEPGEPGASGPMGPRGPPGPPG 227

Query: 742 LGGGAFGDARPGMPS-------VGNSGLPGLGLDVPGFGG--GPNNLSGPSGFGG--GPQ 790
             G      +PG P         G  GLPG    +PG  G  G + L G  G  G  GP+
Sbjct: 228 KNGDDGEAGKPGRPGERGPPGPQGARGLPGTA-GLPGMKGHRGFSGLDGAKGDAGPAGPK 286

Query: 791 NFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGP--------GPGPGPGPGPIHIGG 842
                PG  G P     GP GL   PG  G P A GP          G    PGP    G
Sbjct: 287 GEPGSPGENGAPGQM--GPRGL---PGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAG 341

Query: 843 PPGFASSSGKPG 854
           PPGF  + G  G
Sbjct: 342 PPGFPGAVGAKG 353



 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 90/273 (32%), Positives = 105/273 (38%), Gaps = 62/273 (22%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPNA----GLPGV-GLPSAGLPGAGLPSTGLPGS--AIT 683
           PP +  K  +  VPG+   PG   A    G PG  G+     P     + G PG+  A  
Sbjct: 651 PPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKG 710

Query: 684 SAGLPGA----------GMP----SAGIPSAGGEEHAFLTVGSKEANNGP---------- 719
            AG PGA          GMP    +AG+P   G+       G K A+  P          
Sbjct: 711 DAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRG---DAGPKGADGSPGKDGVRGLTG 767

Query: 720 ------PFNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMPS-VGNSGLPGLGLDVPGF 772
                 P   PG+ G S   GP   P G  G       PG P   G +G PG     PG 
Sbjct: 768 PIGPPGPAGAPGDKGESGPSGPA-GPTGARGAPGDRGEPGPPGPAGFAGPPGAD-GQPGA 825

Query: 773 GGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPG-FGS-GPPGLGSAPGHLGGPPAFG-PG- 828
            G P + +G  G  G P     GP    GPPG  G+ G PG   A G  G P A G PG 
Sbjct: 826 KGEPGD-AGAKGDAGPP-----GPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGA 879

Query: 829 ------PGPGPGPGPIHIGGPPGFASSSGKPGP 855
                 PGP    GP    GPPG A   G  GP
Sbjct: 880 AGRVGPPGPSGNAGP---PGPPGPAGKEGGKGP 909



 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 87/258 (33%), Positives = 98/258 (37%), Gaps = 45/258 (17%)

Query: 631 PPAQGKKGLKMPV-----PGNPAVPGMPN-AGLPG-VGLPSA----GLPGAGLPS--TGL 677
           P A G  G K P      PG     G P  AG PG  GLP A    G PG+  P   TG 
Sbjct: 496 PGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGP 555

Query: 678 PGSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPP- 736
           PG A    G PG   P    P A G+       G K A   P     G  G     GPP 
Sbjct: 556 PGPA-GQDGRPGPPGP----PGARGQAGVMGFPGPKGAAGEP-----GKAGERGVPGPPG 605

Query: 737 -IPPPGLGG--GAFGDARPGMP-----------SVGNSGLPGLG-----LDVPGFGGGPN 777
            + P G  G  GA G   P  P           S G  GLPG          PG  G P 
Sbjct: 606 AVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPG 665

Query: 778 NLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGP 837
           +L  P   G   +    G   + GPPG  +GP G   APG+ G     G    PG    P
Sbjct: 666 DLGAPGPSGARGERGFPGERGVQGPPG-PAGPRGANGAPGNDGAKGDAGAPGAPGSQGAP 724

Query: 838 IHIGGPPGFASSSGKPGP 855
             + G PG   ++G PGP
Sbjct: 725 -GLQGMPGERGAAGLPGP 741



 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 93/268 (34%), Positives = 99/268 (36%), Gaps = 54/268 (20%)

Query: 630  NPPAQGKKGLKMPVPGNPAVPGMPN----AGLPGV----GLPSAGLPG-AGLPSTGLPGS 680
            +P A G  G     PG P   G+       GLPG     G P  GLPG +G P    P  
Sbjct: 936  SPGADGPAG----APGTPGPQGIAGQRGVVGLPGQRGERGFP--GLPGPSGEPGKQGPSG 989

Query: 681  AITSAGLPGAGMPS--AGIPSAGGEEHAFLTVGSKEANNGP----------PFNFPGNFG 728
            A    G PG   P   AG P   G E A    GS   +  P          P   PG  G
Sbjct: 990  ASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPG 1049

Query: 729  GSNAFGPPIP-----------PPGLGG-----GAFGDARPGMPSVGNSGLPGLGLDVPGF 772
               A GP  P           P G  G     GA G A P  P  G+ G  G   D  G 
Sbjct: 1050 APGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPR-GDKGETGEQGD-RGI 1107

Query: 773  GG--GPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGH---LGGPPAFGP 827
             G  G + L GP G  G P     GP    GP G   GPPG   APG     G P   GP
Sbjct: 1108 KGHRGFSGLQGPPGPPGSPGE--QGPSGASGPAG-PRGPPGSAGAPGKDGLNGLPGPIGP 1164

Query: 828  GPGPGPGPGPIHIGGPPGFASSSGKPGP 855
             PGP    G     GPPG     G PGP
Sbjct: 1165 -PGPRGRTGDAGPVGPPGPPGPPGPPGP 1191



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 89/299 (29%), Positives = 101/299 (33%), Gaps = 84/299 (28%)

Query: 630 NPPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSAGLPGAGLP-----STGLPGSAITS 684
           NP A G+ G K    G P + G P  G PG   PS G  G G P     ++G PG+  + 
Sbjct: 387 NPGADGQPGAK-GANGAPGIAGAP--GFPGARGPS-GPQGPGGPPGPKGNSGEPGAPGSK 442

Query: 685 AGLPGAGMPSA----GIPSAGGEEHAFLTVGSKEANNGP-PFNFPGNFG-----GSNAF- 733
                 G P      G P   GEE      G + A   P P   PG  G     GS  F 
Sbjct: 443 GDTGAKGEPGPVGVQGPPGPAGEE------GKRGARGEPGPTGLPGPPGERGGPGSRGFP 496

Query: 734 ------GPPIPP-----PGLGGGAFGDARPGMPSVGNSGLPGL-GLDVPGFGGGPNNLSG 781
                 GP  P      PG  G        G P  G +GLPG  GL       GP+  +G
Sbjct: 497 GADGVAGPKGPAGERGSPGPAGPKGSPGEAGRP--GEAGLPGAKGLTGSPGSPGPDGKTG 554

Query: 782 PSGFGG-----------------------GPQNFGNGPGSLG-----GPPGF-------- 805
           P G  G                       GP+     PG  G     GPPG         
Sbjct: 555 PPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDG 614

Query: 806 ---GSGPPGLGSAPGHLG-----GPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGPT 856
                GPPG     G  G     G P F   PGP   PG     G  G     G PGP+
Sbjct: 615 EAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPS 673



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 98/324 (30%), Positives = 105/324 (32%), Gaps = 118/324 (36%)

Query: 631  PPAQGKKG-LKMPVPGNPAVPGMP--NAGLPGV--GLPSAGLPGAGLPSTGLPGSAITSA 685
            P   G KG    P P  PA P  P  N G PG      SAG PGA    TG PG+A    
Sbjct: 829  PGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGA----TGFPGAA-GRV 883

Query: 686  GLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPP------ 739
            G PG    +AG P   G          KE   GP     G  G     GPP PP      
Sbjct: 884  GPPGPS-GNAGPPGPPGP-------AGKEGGKGPRGE-TGPAGRPGEVGPPGPPGPAGEK 934

Query: 740  --PGLGGGAFGDARPGMPSV-------------GNSGLPGLGLDVPGFGGGPNNLSGPSG 784
              PG  G A     PG   +             G  G PGL    PG  G P    GPSG
Sbjct: 935  GSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGL----PGPSGEPGK-QGPSG 989

Query: 785  FGG--GPQNFGNGPGSLGGPPGFGS--GPPGLGSAPGHLGGPPAFG-------------- 826
              G  GP     GP  L GPPG     G PG   +PG  G P A G              
Sbjct: 990  ASGERGPPG-PMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP 1048

Query: 827  -----PGP-------------GPGPGPGPI------------------------------ 838
                 PGP             GP    GP+                              
Sbjct: 1049 GAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIK 1108

Query: 839  -HIG-----GPPGFASSSGKPGPT 856
             H G     GPPG   S G+ GP+
Sbjct: 1109 GHRGFSGLQGPPGPPGSPGEQGPS 1132



 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 50/144 (34%), Positives = 56/144 (38%), Gaps = 22/144 (15%)

Query: 725 GNFGGSNAFGPPIPP--------PGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGP 776
           G+ G     GP  PP        PGL G       PG P +G +  P L         G 
Sbjct: 115 GDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGG 174

Query: 777 NNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGP-GPGPGPGP 835
            ++ GP G         +GP  L GPPG   GP G    PG  G P A GP GP   PGP
Sbjct: 175 ISVPGPMG--------PSGPRGLPGPPG-APGPQGFQGPPGEPGEPGASGPMGPRGPPGP 225

Query: 836 ----GPIHIGGPPGFASSSGKPGP 855
               G     G PG     G PGP
Sbjct: 226 PGKNGDDGEAGKPGRPGERGPPGP 249



 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 83/249 (33%), Positives = 91/249 (36%), Gaps = 58/249 (23%)

Query: 631  PPAQGKKGLKMPV--------PGNPAVPGMPNA----GLPGVGLPSAGLPGAGLPSTGLP 678
            P   GK+G K P         PG    PG P      G PG   P AG PG   P  G+ 
Sbjct: 898  PGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGP-AGAPGTPGPQ-GIA 955

Query: 679  GSAITSAGLPGA----GMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFG 734
            G      GLPG     G P  G+P   GE              GP        G S   G
Sbjct: 956  GQRGV-VGLPGQRGERGFP--GLPGPSGEP----------GKQGPS-------GASGERG 995

Query: 735  PPIP--PPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNF 792
            PP P  PPGL G      R G P  G  G PG     PG   G    +GP+G        
Sbjct: 996  PPGPMGPPGLAGPPGESGREGAP--GAEGSPGRD-GSPG-AKGDRGETGPAG-------- 1043

Query: 793  GNGPGSLGGPPGFGS-GPPGLGSAPGHLGGPPAFGPGP-GPGPGPGPIHIGGPPGFASSS 850
               PG+ G P   G  GP G     G  G  PA   GP GP    GP    GP G    +
Sbjct: 1044 --PPGAPGAPGAPGPVGPAGKSGDRGETG--PAGPAGPVGPVGARGPAGPQGPRGDKGET 1099

Query: 851  GKPGPTVIK 859
            G+ G   IK
Sbjct: 1100 GEQGDRGIK 1108



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 37/128 (28%), Positives = 40/128 (31%), Gaps = 11/128 (8%)

Query: 181 PMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPV-----PTLPPVPPVPPIPPVPSVPPM 235
           P     PP    IP  P LP  P  P  P PP +     P L           +    PM
Sbjct: 122 PRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPM 181

Query: 236 TPLPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNPIQMNSQSSVK 295
            P    SG   L  PP AP P G  G            PM  GP  P  P   N      
Sbjct: 182 GP----SGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPM--GPRGPPGPPGKNGDDGEA 235

Query: 296 PLPINPDD 303
             P  P +
Sbjct: 236 GKPGRPGE 243



 Score = 30.8 bits (68), Expect = 6.1
 Identities = 24/69 (34%), Positives = 27/69 (39%), Gaps = 5/69 (7%)

Query: 176  PSTAS-PMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPP 234
            PS AS P     PP     P    L  +P     P+ PP P        P  PP P  PP
Sbjct: 1131 PSGASGPAGPRGPPGSAGAPGKDGLNGLPG----PIGPPGPRGRTGDAGPVGPPGPPGPP 1186

Query: 235  MTPLPPMSG 243
              P PP +G
Sbjct: 1187 GPPGPPSAG 1195


>gi|126352446 elastin isoform d precursor [Homo sapiens]
          Length = 711

 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 83/248 (33%), Positives = 103/248 (41%), Gaps = 66/248 (26%)

Query: 649 VPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFL 708
           VPG P  G   VG+P AG+PG G+P  G+P   +  AG+PGA +P    P A  +     
Sbjct: 328 VPGGPGFGPGVVGVPGAGVPGVGVPGAGIP--VVPGAGIPGAAVPGVVSPEAAAK----- 380

Query: 709 TVGSKEANNGPPFNFPG-NFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGL 767
              +K A  G     PG   GG       IP  G+G G F    PG   VG  G+PG+  
Sbjct: 381 -AAAKAAKYGAR---PGVGVGG-------IPTYGVGAGGF----PGF-GVGVGGIPGVA- 423

Query: 768 DVPGFGGGPNNLSGPSGFGGGPQ-----------------------------NFGNGPGS 798
            VPG GG P  + G  G G  P+                              FG  PG 
Sbjct: 424 GVPGVGGVP-GVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPG- 481

Query: 799 LGGPPGFGSGP-----PGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKP 853
           +G  PG G  P     PG+G APG +G  P  G  PG G  PG     GP G A+++   
Sbjct: 482 VGVAPGVGVAPGVGVAPGVGLAPG-VGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSA 536

Query: 854 GPTVIKVQ 861
                K Q
Sbjct: 537 AKVAAKAQ 544



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 82/289 (28%), Positives = 106/289 (36%), Gaps = 72/289 (24%)

Query: 632 PAQGKKGLKMPVPGNPAVPG--MPNAGLPGVGLPSA--------------------GLPG 669
           P  G  G+ +P  G P VPG  +P A +PGV  P A                    G+P 
Sbjct: 342 PGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPT 401

Query: 670 AGLPSTGLPGSAITSAGLPG-AGMPSAG-IPSAGG--------EEHAFLTVGSKEANNGP 719
            G+ + G PG  +   G+PG AG+P  G +P  GG        E  A     + +   G 
Sbjct: 402 YGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGT 461

Query: 720 PFNFPGNFGGSNAFGPPIP----PPGLGGGAFGDARPGM---PSVGNSGLPGLGLDVPGF 772
           P           A    +P     PG+G        PG+   P VG +  PG+G+  PG 
Sbjct: 462 PAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA--PGVGV-APGV 518

Query: 773 GGGPN--------------------NLSGPSGFGGGPQNFGNGPGSLG-----GPPGFG- 806
           G  P                      L   +G G G    G G G  G     G PG G 
Sbjct: 519 GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGV 578

Query: 807 -SGPPGLGSAPGHLGGPPAFGPG---PGPGPGPGPIHIGGPPGFASSSG 851
            +G PG G+ PG L    A   G   PG   G G +   G PG    +G
Sbjct: 579 GAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAG 627



 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 67/213 (31%), Positives = 89/213 (41%), Gaps = 29/213 (13%)

Query: 645 GNPAVPGMPNAGLP--GVGLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGG 702
           G  A P +P A +P  G G+    +PG GLP    PG  +  A  PG G+   G+P+  G
Sbjct: 122 GVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGV-YPGGVLPGARFPGVGV-LPGVPTGAG 179

Query: 703 EEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGL 762
            +     VG   A  G P        G   FG P P   LG   +    P +P  G  GL
Sbjct: 180 VKPKAPGVGGAFA--GIP--------GVGPFGGPQPGVPLG---YPIKAPKLP--GGYGL 224

Query: 763 PGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPG-----FGSGPPGLGSAPG 817
           P     +P +G GP  ++G +G  G P   G GP +           FG+G  G+    G
Sbjct: 225 PYTTGKLP-YGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVG 283

Query: 818 HLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSS 850
             G P      PG  PG G I   G P  A+++
Sbjct: 284 GAGVPGV----PGAIPGIGGIAGVGTPAAAAAA 312



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 69/232 (29%), Positives = 88/232 (37%), Gaps = 40/232 (17%)

Query: 633 AQGKKGLKMPVPGNPAVPGMPNAG-LPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPGAG 691
           A G  G  + V G P V G+P  G +PGVG    G+PG G+ S     +A   A   G G
Sbjct: 406 AGGFPGFGVGVGGIPGVAGVPGVGGVPGVG----GVPGVGI-SPEAQAAAAAKAAKYGVG 460

Query: 692 MPSAGIPSAGGEEHAFLTVGSKEANNG----------PPFNFPGNFGGSNAFGPPIPP-- 739
            P+A    A  +   F  V       G          P        G +   G  + P  
Sbjct: 461 TPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVG--VAPGV 518

Query: 740 ---PGLGGGAFGDARPGMPSVG-----------NSGLPGLGLDV--PGFGGGPNNLSGPS 783
              PG+G G    A      V             +G+PGLG+ V  PG G G   + G  
Sbjct: 519 GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAG-VPG-L 576

Query: 784 GFGGGPQNFGNGPGSLGGPPG--FGSGPPGLGSAPGHLGGPPAFGPGPGPGP 833
           G G G   FG  PG+L       +G+  PG+    G LGG    G   G GP
Sbjct: 577 GVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGP 628



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 82/262 (31%), Positives = 109/262 (41%), Gaps = 40/262 (15%)

Query: 646 NPAVPGMPNAGLPGVGLPSAGL-PGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEE 704
           +P+ PG     +PG G+P     PGAGL + G  G A+   G P   +P  G+  AG   
Sbjct: 22  HPSRPGGVPGAIPG-GVPGGVFYPGAGLGALG--GGALGPGGKPLKPVP-GGLAGAG--- 74

Query: 705 HAFLTVGSKEANNGPPFNFPGNFG-GSNAFGPPIPPPGLGGGAFGDARPGMPSVGNS--- 760
                +G+  A   P    PG     + A+       GLGG       PG+  +G S   
Sbjct: 75  -LGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGG------VPGVGGLGVSAAP 127

Query: 761 GLPGLGLDVPGFGGGPNNLSG---PSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPG 817
            +PG  +  PG G  P  + G   P  + GG       PG +G  PG  +G      APG
Sbjct: 128 SVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPG-VGVLPGVPTGAGVKPKAPG 186

Query: 818 HLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGK-PGPTVIKVQNMPFTVSIDEILDFF 876
            +GG  A  PG GP  GP P   G P G+   + K PG        +P+T      L + 
Sbjct: 187 -VGGAFAGIPGVGPFGGPQP---GVPLGYPIKAPKLPGG-----YGLPYTTG---KLPYG 234

Query: 877 YGYQVIPGSVCLKYNEKGMPTG 898
           YG    PG V     + G PTG
Sbjct: 235 YG----PGGVAGAAGKAGYPTG 252



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 56/177 (31%), Positives = 70/177 (39%), Gaps = 46/177 (25%)

Query: 665 AGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFP 724
           AG+PG G+   G+PG  +  AG+PG G+  AG+P  G    A     +K A  G     P
Sbjct: 553 AGIPGLGV-GVGVPGLGV-GAGVPGLGV-GAGVPGFGAVPGAL--AAAKAAKYGAAV--P 605

Query: 725 GNFGGSNAFGPPIPPPGLGG-------------------GAFGDARPGMPSVGNSGLPGL 765
           G  GG  A G    P G+ G                   G  G A  G   VG  G+PG+
Sbjct: 606 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV 665

Query: 766 GLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGP--PG---LGSAPG 817
           G    G GG P   +  +   G           +   PGFG  P  PG   LG A G
Sbjct: 666 G----GLGGIPPAAAAKAAKYG-----------VAARPGFGLSPIFPGGACLGKACG 707



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 31/102 (30%), Positives = 40/102 (39%), Gaps = 16/102 (15%)

Query: 648 AVPGMPNA--GLPGVGLPSAGLPGAGLPSTGLPGSA---------ITSAGLPGAGMPSAG 696
           AVPG+      L GVG+P  G+ GAG  +      A         + +AGL G G+   G
Sbjct: 603 AVPGVLGGLGALGGVGIPG-GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLG 661

Query: 697 IPSAGGEEHAFLTVGSKEANNG----PPFNFPGNFGGSNAFG 734
           +P  GG         +K A  G    P F     F G    G
Sbjct: 662 VPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLG 703


>gi|126352440 elastin isoform a precursor [Homo sapiens]
          Length = 724

 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 83/248 (33%), Positives = 103/248 (41%), Gaps = 66/248 (26%)

Query: 649 VPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFL 708
           VPG P  G   VG+P AG+PG G+P  G+P   +  AG+PGA +P    P A  +     
Sbjct: 323 VPGGPGFGPGVVGVPGAGVPGVGVPGAGIP--VVPGAGIPGAAVPGVVSPEAAAK----- 375

Query: 709 TVGSKEANNGPPFNFPG-NFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGL 767
              +K A  G     PG   GG       IP  G+G G F    PG   VG  G+PG+  
Sbjct: 376 -AAAKAAKYGAR---PGVGVGG-------IPTYGVGAGGF----PGF-GVGVGGIPGVA- 418

Query: 768 DVPGFGGGPNNLSGPSGFGGGPQ-----------------------------NFGNGPGS 798
            VPG GG P  + G  G G  P+                              FG  PG 
Sbjct: 419 GVPGVGGVP-GVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPG- 476

Query: 799 LGGPPGFGSGP-----PGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKP 853
           +G  PG G  P     PG+G APG +G  P  G  PG G  PG     GP G A+++   
Sbjct: 477 VGVAPGVGVAPGVGVAPGVGLAPG-VGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSA 531

Query: 854 GPTVIKVQ 861
                K Q
Sbjct: 532 AKVAAKAQ 539



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 82/289 (28%), Positives = 106/289 (36%), Gaps = 72/289 (24%)

Query: 632 PAQGKKGLKMPVPGNPAVPG--MPNAGLPGVGLPSA--------------------GLPG 669
           P  G  G+ +P  G P VPG  +P A +PGV  P A                    G+P 
Sbjct: 337 PGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPT 396

Query: 670 AGLPSTGLPGSAITSAGLPG-AGMPSAG-IPSAGG--------EEHAFLTVGSKEANNGP 719
            G+ + G PG  +   G+PG AG+P  G +P  GG        E  A     + +   G 
Sbjct: 397 YGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGT 456

Query: 720 PFNFPGNFGGSNAFGPPIP----PPGLGGGAFGDARPGM---PSVGNSGLPGLGLDVPGF 772
           P           A    +P     PG+G        PG+   P VG +  PG+G+  PG 
Sbjct: 457 PAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA--PGVGV-APGV 513

Query: 773 GGGPN--------------------NLSGPSGFGGGPQNFGNGPGSLG-----GPPGFG- 806
           G  P                      L   +G G G    G G G  G     G PG G 
Sbjct: 514 GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGV 573

Query: 807 -SGPPGLGSAPGHLGGPPAFGPG---PGPGPGPGPIHIGGPPGFASSSG 851
            +G PG G+ PG L    A   G   PG   G G +   G PG    +G
Sbjct: 574 GAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAG 622



 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 70/223 (31%), Positives = 88/223 (39%), Gaps = 51/223 (22%)

Query: 638 GLKMPVPGNPAVPG-MPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGL----PGAGM 692
           G  +P PG    PG +P  GLPGV  P   LPGA  P  G+     T AG+    PG G 
Sbjct: 126 GAVVPQPGAGVKPGKVPGVGLPGV-YPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 184

Query: 693 PSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAFGDARP 752
             AGIP  G                         FGG        P PG+  G +    P
Sbjct: 185 AFAGIPGVGP------------------------FGG--------PQPGVPLG-YPIKAP 211

Query: 753 GMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPG-----FGS 807
            +P  G  GLP     +P +G GP  ++G +G  G P   G GP +           FG+
Sbjct: 212 KLP--GGYGLPYTTGKLP-YGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGA 268

Query: 808 GPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSS 850
           G  G+    G  G P      PG  PG G I   G P  A+++
Sbjct: 269 GAAGVLPGVGGAGVPGV----PGAIPGIGGIAGVGTPAAAAAA 307



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 61/184 (33%), Positives = 74/184 (40%), Gaps = 25/184 (13%)

Query: 665 AGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFP 724
           AG+PG G+   G+PG  +  AG+PG G+  AG+P  G    A     +K A  G     P
Sbjct: 548 AGIPGLGV-GVGVPGLGV-GAGVPGLGV-GAGVPGFGAVPGAL--AAAKAAKYGAAV--P 600

Query: 725 GNFGGSNAFGPPIPPPGLGGG------AFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNN 778
           G  GG  A G    P G+ G       A   A       G  G  GLG    G G G   
Sbjct: 601 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLG----GLGVGGLG 656

Query: 779 LSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPI 838
           + G  G GG P      P +      +G+   GLG   G  G  P  G    PG G  PI
Sbjct: 657 VPGVGGLGGIP------PAAAAKAAKYGAA--GLGGVLGGAGQFPLGGVAARPGFGLSPI 708

Query: 839 HIGG 842
             GG
Sbjct: 709 FPGG 712



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 73/243 (30%), Positives = 90/243 (37%), Gaps = 46/243 (18%)

Query: 635 GKKGLKMPVPGNPAVPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPS 694
           G K LK PVPG     G+  AGL G GL     P    P   +PG    +A    A    
Sbjct: 59  GGKPLK-PVPG-----GLAGAGL-GAGL--GAFPAVTFPGALVPGGVADAAAAYKAAKAG 109

Query: 695 AGIPSAGGEEHAFLTVGSKEANNG--------PPFNFPGNFGGSNAFGPPIPP----PGL 742
           AG+    G     ++ G+     G        P    PG + G    G   P     PG+
Sbjct: 110 AGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGV 169

Query: 743 GGGAFGDARPGMPSVGN--SGLPGLGLDVPGFGGGPNNLSG--------PSGFG----GG 788
             GA    +P  P VG   +G+PG+G   P  G  P    G        P G+G     G
Sbjct: 170 PTGA--GVKPKAPGVGGAFAGIPGVG---PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTG 224

Query: 789 PQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPA-----FGPG-PGPGPGPGPIHIGG 842
              +G GPG + G  G    P G G  P       A     FG G  G  PG G   + G
Sbjct: 225 KLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPG 284

Query: 843 PPG 845
            PG
Sbjct: 285 VPG 287



 Score = 57.0 bits (136), Expect = 8e-08
 Identities = 82/260 (31%), Positives = 103/260 (39%), Gaps = 41/260 (15%)

Query: 646 NPAVPGMPNAGLPGVGLPSAGL-PGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEE 704
           +P+ PG     +PG G+P     PGAGL + G  G A+   G P   +P       GG  
Sbjct: 22  HPSRPGGVPGAIPG-GVPGGVFYPGAGLGALG--GGALGPGGKPLKPVP-------GGLA 71

Query: 705 HAFLTVGSKEANNGPPFNFPGNF-GGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGL- 762
            A L  G       P   FPG    G  A           G   G    G+P VG  G+ 
Sbjct: 72  GAGLGAG---LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLG----GVPGVGGLGVS 124

Query: 763 PGLGLDVPGFGGGPNNLSG---PSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHL 819
            G  +  PG G  P  + G   P  + GG       PG +G  PG  +G      APG +
Sbjct: 125 AGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPG-VGVLPGVPTGAGVKPKAPG-V 182

Query: 820 GGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGK-PGPTVIKVQNMPFTVSIDEILDFFYG 878
           GG  A  PG GP  GP P   G P G+   + K PG        +P+T      L + YG
Sbjct: 183 GGAFAGIPGVGPFGGPQP---GVPLGYPIKAPKLPGG-----YGLPYTTG---KLPYGYG 231

Query: 879 YQVIPGSVCLKYNEKGMPTG 898
               PG V     + G PTG
Sbjct: 232 ----PGGVAGAAGKAGYPTG 247



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 38/117 (32%), Positives = 48/117 (41%), Gaps = 23/117 (19%)

Query: 648 AVPGMPNA--GLPGVGLPSAGLPGAGLPSTGLPGSA---------ITSAGLPGAGMPSAG 696
           AVPG+      L GVG+P  G+ GAG  +      A         + +AGL G G+   G
Sbjct: 598 AVPGVLGGLGALGGVGIPG-GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLG 656

Query: 697 IPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPG 753
           +P  GG         +K A  G      G  GG+  F        LGG A   ARPG
Sbjct: 657 VPGVGGLGGIPPAAAAKAAKYGAA-GLGGVLGGAGQF-------PLGGVA---ARPG 702


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 101/285 (35%), Positives = 116/285 (40%), Gaps = 67/285 (23%)

Query: 611 GREAFVHVVTLEDMREIEKNPPAQGKKG--LKMPVP-------GNPAVPGMPNA-GLPGV 660
           G   +  V  ++ M++    PP +  KG  L+MP+P       G P  PG P   G PG 
Sbjct: 34  GAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGP 93

Query: 661 -GLPSAGLPGAGLPST-GLPGSAITSAGLPG-AGMPSAGIPSAGGEEHAFLTVGSKEANN 717
            G P  G PG G P   G PG A    G PG + M  AG P   G+              
Sbjct: 94  PGFP--GKPGMGKPGLHGQPGPA----GPPGFSRMGKAGPPGLPGKV------------- 134

Query: 718 GPPFN-----FPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGF 772
           GPP        PG  G     GPP  PPGL G + G   PG P  G  G+PG     PGF
Sbjct: 135 GPPGQPGLRGEPGIRGDQGLRGPP-GPPGLPGPS-GITIPGKP--GAQGVPG----PPGF 186

Query: 773 GG--GPNNLSGPSGFGG--GPQNFGN-------GPGSLGGPPGF----GSGPPGLGSAPG 817
            G  GP    GP G  G  G    G        G G   GPPG     G G PGL   PG
Sbjct: 187 QGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPG 246

Query: 818 HLGGPPAFGPG--PGPGPGPGPIHIGGPP-----GFASSSGKPGP 855
             G     GP   PGP   PG +   GPP     G   ++G PGP
Sbjct: 247 APGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGP 291



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 100/278 (35%), Positives = 109/278 (39%), Gaps = 73/278 (26%)

Query: 627 IEKNPPAQGKKGLK--MPVPGNPAVPGMPN----AGLPGVGLPSAGLPGA----GLPST- 675
           I   P AQG  G       PG    PG P      G  GVG P  GLPGA    G P   
Sbjct: 171 IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQP--GLPGAPGQGGAPGPP 228

Query: 676 GLPGSAITSAGLPGAGMPSA-GIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFG 734
           GLPG A       G G P   G+P A G++            +GPP   PG  G   A G
Sbjct: 229 GLPGPA-------GLGKPGLDGLPGAPGDK----------GESGPP-GVPGPRGEPGAVG 270

Query: 735 PPIPPPGLGG----GAFGDARPGMPS-----VGNSGLPGL----GLDVPGFGG-----GP 776
           P   PPG+ G    GA G   P  PS      G  G PGL    G  +PG  G     GP
Sbjct: 271 PK-GPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGP 329

Query: 777 NNLSGPSGFGGGPQNFGN----GPGSLGGPPGFGSGPPGLGSAPGHLGGP-PAFGPGPGP 831
             + G  G  G P   G     GP  LGGPPG     PG    PG  G P P    GPG 
Sbjct: 330 AGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGL----PGSAGLPGRRGPPGPKGEAGPGG 385

Query: 832 GPG-------PGPIHIGGPPG------FASSSGKPGPT 856
            PG        GP  + G PG         + G PGPT
Sbjct: 386 PPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPT 423



 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 100/288 (34%), Positives = 115/288 (39%), Gaps = 69/288 (23%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPNA-------GLPGVGLP-SAGLPGAGLPS--TGLPGS 680
           P A G KG   P PG P   G P A       G+ GVG+P +AGLPG   PS   G PG+
Sbjct: 245 PGAPGDKGESGP-PGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGT 303

Query: 681 -------AITSAGLPGAGMPS-----AGIPSAGGE-----EHAFLTVGSKEANNGPPFNF 723
                    T  G+PG   P      AG+P   G+     E         +   GPP   
Sbjct: 304 RGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPP-GL 362

Query: 724 PGNFGGSNAFGPPIP--------PPGLGG-----GAFGDA-RPGMPSVGNSGLPGLGLDV 769
           PG+ G     GPP P        PPG+ G     G  G A +PG+P  G  GLPG     
Sbjct: 363 PGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVP--GERGLPGA--HG 418

Query: 770 PGFGGGPNNLSGPSGFGGGPQNFG----NGPGSLGGPPGFG--SGPPGLGSAPGHLG--- 820
           P    GP    G +G  GGP   G     G   L G PG    SG PGL    G +G   
Sbjct: 419 PPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQG 478

Query: 821 -----------GPPAFGPGPGPGP-GP-GPIHIGGPPGFASSSGKPGP 855
                      GPP  G    PG  GP GP  + G PG     G PGP
Sbjct: 479 LPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGP 526



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 55/150 (36%), Positives = 58/150 (38%), Gaps = 31/150 (20%)

Query: 724 PGNFGGSNAFGPPIPP----------PGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFG 773
           PG  G     GPP PP          PGL G       PG   +G +G PGL    PG  
Sbjct: 79  PGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGL----PGKV 134

Query: 774 GGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPG-PGPG 832
           G P    G  G  G P     G   L GPPG    PPGL   PG  G      PG PG  
Sbjct: 135 GPP----GQPGLRGEPGI--RGDQGLRGPPG----PPGL---PGPSG---ITIPGKPGAQ 178

Query: 833 PGPGPIHIGGPPGFASSSGKPGPTVIKVQN 862
             PGP    G PG     G PG   +K  N
Sbjct: 179 GVPGPPGFQGEPGPQGEPGPPGDRGLKGDN 208



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 20/83 (24%)

Query: 631 PPAQGKKGLKMPV--PGNPAVPGMPNA----GLPGVGLPSAGLPGAGLPSTGLPG----- 679
           P   G  G+  P   PG P  PG P A    G+ G+ LP+ G+ GA L   G P      
Sbjct: 509 PGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGE 568

Query: 680 ---------SAITSAGLPGAGMP 693
                    +A+ ++  P +GMP
Sbjct: 569 LSAHATPAFTAVLTSPFPASGMP 591



 Score = 35.8 bits (81), Expect = 0.19
 Identities = 30/97 (30%), Positives = 35/97 (36%), Gaps = 8/97 (8%)

Query: 186 PPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLP------PVPPVPPIPPVPSVPPMTPLP 239
           P   I P+   P  PP        +  P+P LP      P PP  P P  P  PP  P  
Sbjct: 40  PVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGK 99

Query: 240 PMSGMPPLN--PPPVAPLPAGMNGSGAPMNLNNNLNP 274
           P  G P L+  P P  P      G   P  L   + P
Sbjct: 100 PGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGP 136



 Score = 33.9 bits (76), Expect = 0.72
 Identities = 22/72 (30%), Positives = 28/72 (38%), Gaps = 7/72 (9%)

Query: 173 STVPSTASPMNTVPPPPIPPIPAMPSLPPMPSI-----PPIPVPPPVPTLPPVPPV--PP 225
           S +P    P   + P  +P +   P LP  P       P    P   P +P  P +  PP
Sbjct: 462 SGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPP 521

Query: 226 IPPVPSVPPMTP 237
            PP P  PP  P
Sbjct: 522 GPPGPPGPPGAP 533



 Score = 30.8 bits (68), Expect = 6.1
 Identities = 32/114 (28%), Positives = 39/114 (34%), Gaps = 34/114 (29%)

Query: 186 PPPPIPPIPAMPSLPPMPSIPPIPVPP-----PVPTLPPVPP------------VPPIPP 228
           P PP  P P+  ++P  P    +P PP     P P   P PP             P +P 
Sbjct: 158 PGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPG 217

Query: 229 VPSV-----PPMTPLPPMSGMPPLNP------------PPVAPLPAGMNGSGAP 265
            P       PP  P P   G P L+             PP  P P G  G+  P
Sbjct: 218 APGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGP 271


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score = 87.4 bits (215), Expect = 6e-17
 Identities = 99/253 (39%), Positives = 108/253 (42%), Gaps = 41/253 (16%)

Query: 628 EKNPPAQGKKGLKMPVPGNPAVPGMPNA-GLPGVGLPSAGLPGAGLPSTGLPG--SAITS 684
           E+ P   GK G     PG P +PG     G PG+  P  G PG G P  GLPG       
Sbjct: 257 ERGPEGIGKPGAA-GAPGQPGIPGTKGLPGAPGIAGPP-GPPGFGKP--GLPGLKGERGP 312

Query: 685 AGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGG 744
           AGLPG        P A GE+      G K    GPP    GN G     G P    GL G
Sbjct: 313 AGLPGG-------PGAKGEQGPAGLPG-KPGLTGPP----GNMGPQGPKGIP-GSHGLPG 359

Query: 745 --GAFGDARP-GMPSV-GNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLG 800
             G  G A P G P   G  G PG     PG+ G P  L GP G  G P   G+ PG +G
Sbjct: 360 PKGETGPAGPAGYPGAKGERGSPGSD-GKPGYPGKPG-LDGPKGNPGLPGPKGD-PG-VG 415

Query: 801 GPPGFGS--GPPGLGSAPGHLGGPPAFGPGPGPG-PGP-GPIHIGGPPGFASSS------ 850
           GPPG     GP G    PGH G     GP   PG PG  GPI   G PGF  S       
Sbjct: 416 GPPGLPGPVGPAGAKGMPGHNGEA---GPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSP 472

Query: 851 GKPGPTVIKVQNM 863
           G PGP  I  + +
Sbjct: 473 GPPGPAGIATKGL 485



 Score = 84.3 bits (207), Expect = 5e-16
 Identities = 90/262 (34%), Positives = 103/262 (39%), Gaps = 39/262 (14%)

Query: 630 NPPAQGKKGLKMP----VPGNPAVPGMPNAGLPGVGLP--------SAGLPGAGLPS--T 675
           +P  QG+ GL  P      G P VPG+P  G PG   P         AGLPG   P    
Sbjct: 87  SPGLQGEPGLPGPPGPSAVGKPGVPGLP--GKPGERGPYGPKGDVGPAGLPGPRGPPGPP 144

Query: 676 GLPGSA-ITSAGLPGAGMPSAGIPSAG--GEEHAFLTVGSKEANNGPPFNFPGNFGGSNA 732
           G+PG A I+  G PG   P+      G  GE+ A    G         +  PG  G    
Sbjct: 145 GIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGL 204

Query: 733 FGP-----PIPPPGLGGGAFGDARPGMPSV-GNSGLPG-LGLDVPGFGGGPNNLSGPSGF 785
            GP     P  PPG+G        PG P + G+ G PG +G   P    GP    GP G 
Sbjct: 205 PGPQGPTGPSGPPGVGKRGENGV-PGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI 263

Query: 786 G-----GGPQNFG-NGPGSLGGPPGFGS--GPPGLG--SAPGHLG--GPPAFGPGPGPGP 833
           G     G P   G  G   L G PG     GPPG G    PG  G  GP     GPG   
Sbjct: 264 GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKG 323

Query: 834 GPGPIHIGGPPGFASSSGKPGP 855
             GP  + G PG     G  GP
Sbjct: 324 EQGPAGLPGKPGLTGPPGNMGP 345



 Score = 84.0 bits (206), Expect = 6e-16
 Identities = 84/248 (33%), Positives = 92/248 (37%), Gaps = 61/248 (24%)

Query: 644 PGNPAVPGMPNAGLPGV-GLPSAGLPGAGLPST-------GLPGSA-----------ITS 684
           PG    PG P  G PG+ G P  GLPG   PS        GLPG             +  
Sbjct: 74  PGPSGPPGKPGYGSPGLQGEP--GLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGP 131

Query: 685 AGLPGAGMPSA--GIPSAGGEEHAFLTVGSKEANNGP-----PFNFPGNFGGSNAFGPPI 737
           AGLPG   P    GIP   G     ++V  K    GP     P  FPG  G         
Sbjct: 132 AGLPGPRGPPGPPGIPGPAG-----ISVPGKPGQQGPTGAPGPRGFPGEKGAPGV----- 181

Query: 738 PPPGLGG--GAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNG 795
             PG+ G  G  G   PG P  G  GLPG          GP   SGP G G   +N   G
Sbjct: 182 --PGMNGQKGEMGYGAPGRP--GERGLPG--------PQGPTGPSGPPGVGKRGENGVPG 229

Query: 796 PGSLGGPPGFGS-----GPPGLGSAPGHLG----GPPAFGPGPGPGPGPGPIHIGGPPGF 846
              + G  GF       GPPG    PG  G    G P     PG    PG   + G PG 
Sbjct: 230 QPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGI 289

Query: 847 ASSSGKPG 854
           A   G PG
Sbjct: 290 AGPPGPPG 297



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 49/125 (39%), Positives = 52/125 (41%), Gaps = 21/125 (16%)

Query: 734 GPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGG-GPQNF 792
           GPP  P G  G       PG P  G+ GL G     PG  G P    GPS  G  G    
Sbjct: 63  GPP-GPAGPRGHPGPSGPPGKPGYGSPGLQG----EPGLPGPP----GPSAVGKPGVPGL 113

Query: 793 GNGPGSLG--GPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSS 850
              PG  G  GP G   GP GL   PG     P   PGP   PGP  I + G PG    +
Sbjct: 114 PGKPGERGPYGPKG-DVGPAGL---PG-----PRGPPGPPGIPGPAGISVPGKPGQQGPT 164

Query: 851 GKPGP 855
           G PGP
Sbjct: 165 GAPGP 169



 Score = 53.5 bits (127), Expect = 9e-07
 Identities = 44/119 (36%), Positives = 50/119 (42%), Gaps = 19/119 (15%)

Query: 753 GMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGN----GPGSLGGPPGFGS- 807
           G+   G  G PG     P    GP    GPSG  G P  +G+    G   L GPPG  + 
Sbjct: 52  GIAVRGEQGTPG-----PPGPAGPRGHPGPSGPPGKP-GYGSPGLQGEPGLPGPPGPSAV 105

Query: 808 GPPGLGSAPGHLGGPPAFGPGPGPGPG--PGPIHIGGPPGFASSSGKPGPTVIKVQNMP 864
           G PG+   PG  G    +GP    GP   PGP    GPPG       PGP  I V   P
Sbjct: 106 GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGI------PGPAGISVPGKP 158



 Score = 38.9 bits (89), Expect = 0.023
 Identities = 34/103 (33%), Positives = 41/103 (39%), Gaps = 10/103 (9%)

Query: 169 PTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTL--PPVPPVPPI 226
           P  +  +P T  P+    PP IP  P     P  P  PP P       L  P  PP PP 
Sbjct: 441 PRGAPGIPGTRGPIG---PPGIPGFPGSKGDPGSPG-PPGPAGIATKGLNGPTGPPGPPG 496

Query: 227 PPVPSVPPMTPLPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLN 269
           P   S  P  P PP     P  PP  A +P G   +G   +L+
Sbjct: 497 PRGHSGEPGLPGPP----GPPGPPGQAVMPEGFIKAGQRPSLS 535



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 35/124 (28%), Positives = 39/124 (31%), Gaps = 26/124 (20%)

Query: 185 VPPPPIPPIPAMPSLPPMPSIP-----------------PIPVPPPVPTLPPVPPVPPIP 227
           +P PP P     P +P +P  P                 P P  PP P   P P    +P
Sbjct: 96  LPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVP 155

Query: 228 PVPSVPPMTPLPPMSGMPPLNPPPVAPLPAGMNGS------GAPMNLNNNLNPMFLGPLN 281
             P     T  P   G P     P  P   GMNG       GAP        P   GP  
Sbjct: 156 GKPGQQGPTGAPGPRGFPGEKGAPGVP---GMNGQKGEMGYGAPGRPGERGLPGPQGPTG 212

Query: 282 PVNP 285
           P  P
Sbjct: 213 PSGP 216



 Score = 30.4 bits (67), Expect = 8.0
 Identities = 31/98 (31%), Positives = 34/98 (34%), Gaps = 6/98 (6%)

Query: 218 PPVPPVPPIPPVPSVPPMTPLPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMFL 277
           PP P  P   P PS PP     P  G P L   P  P P G +  G P        P   
Sbjct: 64  PPGPAGPRGHPGPSGPPG---KPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGER 120

Query: 278 GPLNP---VNPIQMNSQSSVKPLPINPDDLYVSVHGMP 312
           GP  P   V P  +         P  P    +SV G P
Sbjct: 121 GPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKP 158


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score = 86.7 bits (213), Expect = 9e-17
 Identities = 88/226 (38%), Positives = 94/226 (41%), Gaps = 37/226 (16%)

Query: 645  GNPAVPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEE 704
            G+P +PG P  GLPG      G PG    S G PG  I   G PGA + S G+P   GE 
Sbjct: 1018 GSPGLPGPP--GLPGQR-GEEGPPGMR-GSPGPPGP-IGPPGFPGA-VGSPGLPGLQGER 1071

Query: 705  HAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPP-----GLGGGAFGDARPGMPSVGN 759
                  G K    GPP    G  G   A GPP  P      G  G A     PG P  G+
Sbjct: 1072 GLTGLTGDK-GEPGPP----GQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPP--GS 1124

Query: 760  SGLPGLGLDVPGFGGGPNNLSGPSGFGG--GPQNFGNGPGSLG--GPPGF-----GSGPP 810
             GLPG     P    GP    GP G  G  G Q F   PG  G  GPPGF       GPP
Sbjct: 1125 EGLPG-----PPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPP 1179

Query: 811  GLGSAPGHLG--GPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPG 854
            G  +  G  G  GP      PGP   PGP  I GP G     GK G
Sbjct: 1180 GPQAEKGSEGIRGPSGLPGSPGP---PGPPGIQGPAGLDGLDGKDG 1222



 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 93/274 (33%), Positives = 108/274 (39%), Gaps = 48/274 (17%)

Query: 634  QGKKGLKMP--VPGNPAVPGMPN----AGLPGV----GLPSA-GLPG-AGLPST-GLPG- 679
            +G +G++ P  +PG+P  PG P     AGL G+    G P   G PG AG P   G PG 
Sbjct: 1185 KGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGF 1244

Query: 680  -SAITSAGLPG----AGMP----SAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGS 730
                   GLPG     G P    S G P A GE  A       +   GPP +        
Sbjct: 1245 KGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAM----GPQGRPGPPGHV------- 1293

Query: 731  NAFGPPIPP--PGLGGGAFGDARPGMPSVGNSGLPGL-GLDVPGFGGGPNNLSGPSGFGG 787
               GPP PP  PG  G +    +    + G  GL GL G   P    GP    G  G  G
Sbjct: 1294 ---GPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAG 1350

Query: 788  -----GPQNFGNGPGSLGGPPGFGS-GPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIG 841
                 G Q F   PG  G P   G  G  G     G  GGP   G   GP   PGP    
Sbjct: 1351 KEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSG-SMGPVGPPGPAGER 1409

Query: 842  GPPGFASSSGKPGPTVIKVQNMPFTVSIDEILDF 875
            G PG    SG PG   +   +M   V+ DEI  F
Sbjct: 1410 GHPGAPGPSGSPGLPGVP-GSMGDMVNYDEIKRF 1442



 Score = 71.2 bits (173), Expect = 4e-12
 Identities = 82/249 (32%), Positives = 97/249 (38%), Gaps = 60/249 (24%)

Query: 634  QGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSAGLPGA-GLPSTGLPGSAITSAGLPGAGM 692
            +G+KG +    G P VPG+ N     + L       A G  S G PG  + S GLPG   
Sbjct: 973  KGEKGDQ----GIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPG-CVGSPGLPGP-- 1025

Query: 693  PSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIP--PPGLGGGAFGDA 750
               G+P   GEE             GPP       G   + GPP P  PPG  G      
Sbjct: 1026 --PGLPGQRGEE-------------GPP-------GMRGSPGPPGPIGPPGFPGAV---G 1060

Query: 751  RPGMPSV-GNSGLPGLGLDV--PGFGGGPN--NLSGPSGFGG--GPQNFGNGPGSLG--G 801
             PG+P + G  GL GL  D   PG  G P     +GP G  G  G + +    G  G  G
Sbjct: 1061 SPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPG 1120

Query: 802  PPGFGS--GPPGLGSAPGHLG--------------GPPAFGPGPGPGPGPGPIHIGGPPG 845
            PPG     GPPG     G  G              G P F   PGP   PG +   GPPG
Sbjct: 1121 PPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPG 1180

Query: 846  FASSSGKPG 854
              +  G  G
Sbjct: 1181 PQAEKGSEG 1189



 Score = 70.1 bits (170), Expect = 9e-12
 Identities = 83/266 (31%), Positives = 100/266 (37%), Gaps = 49/266 (18%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPNA-GLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPG 689
           P  +G+ G  +P  G+P + G+    G P +   S       + STG  G      G PG
Sbjct: 527 PGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDV----GSPG 582

Query: 690 AGMPS----AGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPP-PGLGG 744
            G+P     AG+P   GE+  F   G    + GPP    G  G   A G P  P P L  
Sbjct: 583 FGLPGLPGRAGVPGLKGEKGNFGEAGPA-GSPGPPGPV-GPAGIKGAKGEPCEPCPALSN 640

Query: 745 GAFGDAR----PGMPS--VGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFG----N 794
              GD R    PG PS   G  G PG GL       G   L G  G  G P + G     
Sbjct: 641 LQDGDVRVVALPG-PSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTT 699

Query: 795 GPGSLGGPPGF--GSGPPG------------------LGSAPGHLG-----GPPAFGPGP 829
           G   L G PG    +GP G                  +   PG  G     GP   G  P
Sbjct: 700 GRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVG-RP 758

Query: 830 GPGPGPGPIHIGGPPGFASSSGKPGP 855
           G    PG   + GPPG     G+PGP
Sbjct: 759 GKPGQPGLPGVQGPPGLKGVQGEPGP 784



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 78/249 (31%), Positives = 94/249 (37%), Gaps = 44/249 (17%)

Query: 630 NPPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPG 689
           +P   G +GL    PG P +PG P  GLPG      G PG        P     S+G+PG
Sbjct: 436 DPGFVGPEGLAGE-PGPPGLPGPPGIGLPGTPGDPGGPPG--------PKGDKGSSGIPG 486

Query: 690 AGMPSA--GIPSAGGEEHAFLTVGSKEANNGPPF-NFPGNFGGSNAFGPPIP---PPGLG 743
              P    G P   GE+     V          F   PG  G     G P+P    PG+ 
Sbjct: 487 KEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQ 546

Query: 744 G--GAFGDARPGMPSV-------------GNSGLPGLGLDVPGFGGGPNNLSGPSGFGGG 788
           G  G  G+      SV             G+ G PG GL  PG  G     +G  G  G 
Sbjct: 547 GIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGL--PGLPG----RAGVPGLKGE 600

Query: 789 PQNFGN-GPGSLGGPPGFGSGPPGLGSAPGHLGGP-PAFGPGPGPGPGPGPIHIGGPPGF 846
             NFG  GP    GPPG   GP G+  A G    P PA           G + +   PG 
Sbjct: 601 KGNFGEAGPAGSPGPPG-PVGPAGIKGAKGEPCEPCPALS-----NLQDGDVRVVALPGP 654

Query: 847 ASSSGKPGP 855
           +   G+PGP
Sbjct: 655 SGEKGEPGP 663



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 91/303 (30%), Positives = 101/303 (33%), Gaps = 87/303 (28%)

Query: 628  EKNPPAQGKKGLKMPVPGNPAVPGMPN----AGLPGVGLPS----------AGLPGAGLP 673
            E  P A G +G   P PG+   PG P     AG+  VGL            AGLPG   P
Sbjct: 1275 EGEPGAMGPQGRPGP-PGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGP 1333

Query: 674  S--TGLPGSAITSAGLPGAGMPSA----GIPSAGGEEHAFLTVGSK-EANNGPPFNFPGN 726
                G PG   T       G P      G P   G+  A    G K +A        PG 
Sbjct: 1334 PGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGA---AGQKGQAGEKGRAGMPGG 1390

Query: 727  FGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLS------ 780
             G S + GP + PPG  G       PG PS G+ GLPG    VPG  G   N        
Sbjct: 1391 PGKSGSMGP-VGPPGPAGERGHPGAPG-PS-GSPGLPG----VPGSMGDMVNYDEIKRFI 1443

Query: 781  --------------------------------GPSGFGGGPQNFGNGPGSLGGPPGFG-- 806
                                            GP G  G P   G  PGS G P   G  
Sbjct: 1444 RQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPG-APGSPGLPGQIGRE 1502

Query: 807  --SGPPGLGSAPGHLGGPPAFG------------PGPGPGPGPGPIHIGGPPGFASSSGK 852
               G PG+   PG  G     G            PGP   PG G +   GP G     G 
Sbjct: 1503 GRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGIPGI 1562

Query: 853  PGP 855
            PGP
Sbjct: 1563 PGP 1565



 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 93/288 (32%), Positives = 119/288 (41%), Gaps = 56/288 (19%)

Query: 620 TLEDMREIEKNPPAQGKKGLK-MPVPGNPAVPGMPNA----GLPGV-GLPSAGLPGAGLP 673
           T+ DM      P  +G++G + +  PG P  PG+P      GL GV G P  G PG G+ 
Sbjct: 733 TVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEP--GPPGRGVQ 790

Query: 674 ST-GLPGSAITSAGLPGA-GMPSA-GIPSAGGEEHAFLTVGSKEANN--GPPFNFPGNFG 728
              G PG+     GLPG  G+P   G P   GE+ A  + G K A    GPP        
Sbjct: 791 GPQGEPGAP----GLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPP-------- 838

Query: 729 GSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGG 788
           G++  GPP              R G    G +GL G     PG   GP    G  G    
Sbjct: 839 GASVSGPP-------------GRDGQQ--GQTGLRG----TPG-EKGPRGEKGEPGECSC 878

Query: 789 PQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFAS 848
           P     G     G PG      G    PG  G PP   PGP PGP PG   + G PG   
Sbjct: 879 PSQ---GDLIFSGMPGAPGLWMGSSWQPGPQG-PPGI-PGP-PGP-PGVPGLQGVPGNNG 931

Query: 849 SSGKPGPTVIKVQNMPFTVSIDEIL--DFFYGYQVIPGSVCLKYNEKG 894
             G+PG T  ++ ++P    + + +  D   G +  PG +  K  EKG
Sbjct: 932 LPGQPGLTA-ELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEK-GEKG 977



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 64/198 (32%), Positives = 75/198 (37%), Gaps = 39/198 (19%)

Query: 668 PGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSK-EANNGPPFNFPGN 726
           P  G    GLPG        PG    S G   A G +   ++  +  +   GP     G 
Sbjct: 335 PKGGKGERGLPGP-------PG----SKGEKGARGNDCVRISPDAPLQCAEGPK----GE 379

Query: 727 FGGSNAFGPPIPPPGLGG-GAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLS--GPS 783
            G S A GP   P   G  G  G+   G    G  G+PG     PG  G P  +   GP 
Sbjct: 380 KGESGALGPSGLPGSTGEKGQKGEKGDG----GIKGVPGK----PGRDGRPGEICVIGPK 431

Query: 784 GFGG-----GPQNFGNGPGSLGGPPGFGSGPPGLG--SAPGHLGGPPAFGPGPGPGPGPG 836
           G  G     GP+     P    GPPG   GPPG+G    PG  GGPP      G    PG
Sbjct: 432 GQKGDPGFVGPEGLAGEP----GPPGL-PGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPG 486

Query: 837 PIHIGGPPGFASSSGKPG 854
               GG PG     G+ G
Sbjct: 487 KEGPGGKPGKPGVKGEKG 504



 Score = 53.5 bits (127), Expect = 9e-07
 Identities = 89/292 (30%), Positives = 103/292 (35%), Gaps = 77/292 (26%)

Query: 631 PPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSA--GLPGAGLPSTGLPGSAITSAGLP 688
           P ++G+KG +    GN  V   P+A L     P    G  GA  PS GLPGS     G  
Sbjct: 348 PGSKGEKGAR----GNDCVRISPDAPLQCAEGPKGEKGESGALGPS-GLPGST-GEKGQK 401

Query: 689 GA-------GMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPP-IP-P 739
           G        G+P  G P   G       +G K     P F  P    G    GPP +P P
Sbjct: 402 GEKGDGGIKGVP--GKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEP--GPPGLPGP 457

Query: 740 PGLG-GGAFGDARPGMP-----SVGNSGLPGLGLDVPGFGGGPNNLSGPSG--------F 785
           PG+G  G  GD  PG P       G+SG+PG   + PG   G   + G  G         
Sbjct: 458 PGIGLPGTPGD--PGGPPGPKGDKGSSGIPGK--EGPGGKPGKPGVKGEKGDPCEVCPTL 513

Query: 786 GGGPQNFGNGPGSLG-----GPPGFGSGPPGLGSAPGHLGGP------------------ 822
             G QNF   PG  G     G P    G PG+    G  G P                  
Sbjct: 514 PEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTG 573

Query: 823 -------PAFG----PGPGPGPG----PGPIHIGGPPGFASSSGKPGPTVIK 859
                  P FG    PG    PG     G     GP G     G  GP  IK
Sbjct: 574 ASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIK 625


>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
           sapiens]
          Length = 406

 Score = 84.7 bits (208), Expect = 4e-16
 Identities = 41/78 (52%), Positives = 50/78 (64%), Gaps = 2/78 (2%)

Query: 181 PMNTVPP-PPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLP 239
           PM  VPP PP+ P+P  P + P+P  PP+   PP P +  VPP PP+ P+P  PPM PLP
Sbjct: 299 PMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLP 358

Query: 240 PMSGMPPLNP-PPVAPLP 256
           P   M PL P PP+APLP
Sbjct: 359 PGPPMAPLPPGPPMAPLP 376



 Score = 84.3 bits (207), Expect = 5e-16
 Identities = 45/93 (48%), Positives = 54/93 (58%), Gaps = 3/93 (3%)

Query: 169 PTFSSTVPSTASP-MNTVPP-PPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPI 226
           P  S   P    P M  VPP PP+ P+P  P + P+P+ PP+   PP P +  VPP PP+
Sbjct: 277 PPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPM 336

Query: 227 PPVPSVPPMTPLPPMSGMPPLNP-PPVAPLPAG 258
             VP  PPM PLPP   M PL P PP+APLP G
Sbjct: 337 ARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPG 369



 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 62/188 (32%), Positives = 85/188 (45%), Gaps = 40/188 (21%)

Query: 163 GASFGSPTFSST-----VPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPI----PVP-- 211
           GA + +P          VP    P   +P PP+PP P M  +PP P I P+    PVP  
Sbjct: 221 GAYYAAPALDPALCVHLVPQLPRPP-VLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPG 279

Query: 212 ---------------PPVPTLPPVPPVPPIPPVPSVPPMTPL---PPMSGMPPLNP---- 249
                          PP P + PVPP PP+ PVP+ PPM P+   PPM+ +PP  P    
Sbjct: 280 SRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARV 339

Query: 250 ---PPVAPLPAGMNGSGAPMNLNNNLNPMFLG-PLNPVNPIQMNSQSSVKPLPINPDDLY 305
              PP+APLP G     AP+     + P+  G P+ P+ P      + + P+ I    + 
Sbjct: 340 PPGPPMAPLPPG--PPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLAPVHITWAPVI 397

Query: 306 VSVHGMPF 313
            S +  PF
Sbjct: 398 NSYYACPF 405



 Score = 80.9 bits (198), Expect = 5e-15
 Identities = 41/114 (35%), Positives = 64/114 (56%), Gaps = 9/114 (7%)

Query: 151 STASVGTAPPNMGASFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPV 210
           +TA+   A P +    G   +++     A  ++ VP  P PP+  +P +PP P + P+P 
Sbjct: 205 NTATADLAHP-LDMFLGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPP 263

Query: 211 PPPVPTLPPVPPVP------PIPPVPSVPPMTPLPPMSGMPPLNPPPVAPLPAG 258
            PP+  +PP+ PVP      P+PP P + P+ P PPM+ +PP   PP+AP+P G
Sbjct: 264 RPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPW--PPMAPVPTG 315


>gi|74099697 heterogeneous nuclear ribonucleoprotein H2 [Homo
           sapiens]
          Length = 449

 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 61/225 (27%), Positives = 109/225 (48%), Gaps = 22/225 (9%)

Query: 429 GFCVYLKGLPFEAENKHVIDFFK--KLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKA 486
           GF V ++GLP+      V+ FF   K+      I   Y   G+ +GE FVE  +E + K 
Sbjct: 10  GFVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKL 69

Query: 487 ALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQREMILNPEGDVNSAKVCA 546
           AL + ++ MG+R+++V     K    ++D + K     S D        +G V       
Sbjct: 70  ALKKDRETMGHRYVEVF----KSNSVEMDWVLKHTGPNSPDTAN-----DGFVR------ 114

Query: 547 HITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHR 606
            +  +PF  +K +++QF  G+ +  N + + VD  G+  G+A VQF +++ A K+ + H+
Sbjct: 115 -LRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHK 173

Query: 607 KKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPAVPG 651
           +++  R   +   +  ++R    +PP   +K + M  PG    PG
Sbjct: 174 ERIGHRYIEIFKSSRAEVR-THYDPP---RKLMAMQRPGPYDRPG 214



 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 61/220 (27%), Positives = 103/220 (46%), Gaps = 38/220 (17%)

Query: 306 VSVHGMPFSAMENDVRDFFHGLRVD----AVHLLKDHVGRNNGNGLVKFLSPQDTFEALK 361
           V V G+P+S   ++V  FF   ++      +  +    GR +G   V+  S ++   ALK
Sbjct: 13  VKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLALK 72

Query: 362 RNRMLMIQRYVEV--SPATERQWVAAGGHITFKQNMGPSGQTHPPPQTLPRSKSPSGQKR 419
           ++R  M  RYVEV  S + E  WV         ++ GP+      P T            
Sbjct: 73  KDRETMGHRYVEVFKSNSVEMDWVL--------KHTGPNS-----PDTA----------- 108

Query: 420 SRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFR 479
                    GF V L+GLPF    + ++ FF  L+IV + + +     G++TGE FV+F 
Sbjct: 109 -------NDGF-VRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFA 160

Query: 480 NEADYKAALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRK 519
           ++   + AL +HK+ +G+R+I++   ++  +    D  RK
Sbjct: 161 SQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRK 200



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 26/74 (35%), Positives = 45/74 (60%), Gaps = 2/74 (2%)

Query: 429 GFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAAL 488
           G CV+++GLP+ A    + +FF  L+ +   ++I  GP+G+ TGE  VEF    D  AA+
Sbjct: 288 GHCVHMRGLPYRATENDIYNFFSPLNPMR--VHIEIGPDGRVTGEADVEFATHEDAVAAM 345

Query: 489 CRHKQYMGNRFIQV 502
            + K  M +R++++
Sbjct: 346 AKDKANMQHRYVEL 359



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 24/72 (33%), Positives = 44/72 (61%), Gaps = 1/72 (1%)

Query: 858 IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVIDL 917
           ++++ +PF  S +EI+ FF G +++P  + L  + +G  TGEA V F S++ A  A+   
Sbjct: 113 VRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKH 172

Query: 918 NDRPIGSRKVKL 929
            +R IG R +++
Sbjct: 173 KER-IGHRYIEI 183



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 24/79 (30%), Positives = 44/79 (55%), Gaps = 2/79 (2%)

Query: 298 PINPDDLYVSVHGMPFSAMENDVRDFFHGLRV--DAVHLLKDHVGRNNGNGLVKFLSPQD 355
           P   +D +V + G+PF   + ++  FF GL +  + + L  D  GR+ G   V+F S + 
Sbjct: 105 PDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEI 164

Query: 356 TFEALKRNRMLMIQRYVEV 374
             +ALK+++  +  RY+E+
Sbjct: 165 AEKALKKHKERIGHRYIEI 183



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 24/69 (34%), Positives = 38/69 (55%)

Query: 306 VSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEALKRNRM 365
           V + G+P+ A END+ +FF  L    VH+     GR  G   V+F + +D   A+ +++ 
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDKA 350

Query: 366 LMIQRYVEV 374
            M  RYVE+
Sbjct: 351 NMQHRYVEL 359



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 24/69 (34%), Positives = 42/69 (60%), Gaps = 3/69 (4%)

Query: 848 SSSGKPGPTVIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLK--YNEKGMPTGEAMVAFE 905
           S+ G+ G  V+KV+ +P++ S DE++ FF   ++  G+  ++  Y  +G P+GEA V  E
Sbjct: 4   STEGREG-FVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELE 62

Query: 906 SRDEATAAV 914
           S +E   A+
Sbjct: 63  SEEEVKLAL 71



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 4/88 (4%)

Query: 5   IRLQGLPIVAGTMDIRHFFSGLTIPDGG----VHIVGGELGEAFIVFATDEDARLGMMRT 60
           +RL+GLP      +I  FFSGL I   G    V   G   GEAF+ FA+ E A   + + 
Sbjct: 113 VRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKH 172

Query: 61  GGTIKGSKVTLLLSSKTEMQNMIELSRR 88
              I    + +  SS+ E++   +  R+
Sbjct: 173 KERIGHRYIEIFKSSRAEVRTHYDPPRK 200



 Score = 37.0 bits (84), Expect = 0.086
 Identities = 16/54 (29%), Positives = 30/54 (55%), Gaps = 2/54 (3%)

Query: 545 CAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDA 598
           C H+  +P+  T+ D+  F    P++   VH+ +  +G+  G+A V+F   +DA
Sbjct: 290 CVHMRGLPYRATENDIYNFFS--PLNPMRVHIEIGPDGRVTGEADVEFATHEDA 341



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 22/82 (26%), Positives = 41/82 (50%), Gaps = 6/82 (7%)

Query: 4  VIRLQGLPIVAGTMDIRHFFSGLTIPDG--GVHIV----GGELGEAFIVFATDEDARLGM 57
          V++++GLP      ++  FFS   I +G  G+  +    G   GEAF+   ++E+ +L +
Sbjct: 12 VVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLAL 71

Query: 58 MRTGGTIKGSKVTLLLSSKTEM 79
           +   T+    V +  S+  EM
Sbjct: 72 KKDRETMGHRYVEVFKSNSVEM 93



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 28/79 (35%), Positives = 37/79 (46%), Gaps = 14/79 (17%)

Query: 5   IRLQGLPIVAGTMDIRHFFSGLTI--------PDGGVHIVGGELGEAFIVFATDEDARLG 56
           + ++GLP  A   DI +FFS L          PDG V       GEA + FAT EDA   
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRV------TGEADVEFATHEDAVAA 344

Query: 57  MMRTGGTIKGSKVTLLLSS 75
           M +    ++   V L L+S
Sbjct: 345 MAKDKANMQHRYVELFLNS 363


>gi|9624998 heterogeneous nuclear ribonucleoprotein H2 [Homo
           sapiens]
          Length = 449

 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 61/225 (27%), Positives = 109/225 (48%), Gaps = 22/225 (9%)

Query: 429 GFCVYLKGLPFEAENKHVIDFFK--KLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKA 486
           GF V ++GLP+      V+ FF   K+      I   Y   G+ +GE FVE  +E + K 
Sbjct: 10  GFVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKL 69

Query: 487 ALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQREMILNPEGDVNSAKVCA 546
           AL + ++ MG+R+++V     K    ++D + K     S D        +G V       
Sbjct: 70  ALKKDRETMGHRYVEVF----KSNSVEMDWVLKHTGPNSPDTAN-----DGFVR------ 114

Query: 547 HITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHR 606
            +  +PF  +K +++QF  G+ +  N + + VD  G+  G+A VQF +++ A K+ + H+
Sbjct: 115 -LRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHK 173

Query: 607 KKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPAVPG 651
           +++  R   +   +  ++R    +PP   +K + M  PG    PG
Sbjct: 174 ERIGHRYIEIFKSSRAEVR-THYDPP---RKLMAMQRPGPYDRPG 214



 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 61/220 (27%), Positives = 103/220 (46%), Gaps = 38/220 (17%)

Query: 306 VSVHGMPFSAMENDVRDFFHGLRVD----AVHLLKDHVGRNNGNGLVKFLSPQDTFEALK 361
           V V G+P+S   ++V  FF   ++      +  +    GR +G   V+  S ++   ALK
Sbjct: 13  VKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLALK 72

Query: 362 RNRMLMIQRYVEV--SPATERQWVAAGGHITFKQNMGPSGQTHPPPQTLPRSKSPSGQKR 419
           ++R  M  RYVEV  S + E  WV         ++ GP+      P T            
Sbjct: 73  KDRETMGHRYVEVFKSNSVEMDWVL--------KHTGPNS-----PDTA----------- 108

Query: 420 SRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFR 479
                    GF V L+GLPF    + ++ FF  L+IV + + +     G++TGE FV+F 
Sbjct: 109 -------NDGF-VRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFA 160

Query: 480 NEADYKAALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRK 519
           ++   + AL +HK+ +G+R+I++   ++  +    D  RK
Sbjct: 161 SQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRK 200



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 26/74 (35%), Positives = 45/74 (60%), Gaps = 2/74 (2%)

Query: 429 GFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAAL 488
           G CV+++GLP+ A    + +FF  L+ +   ++I  GP+G+ TGE  VEF    D  AA+
Sbjct: 288 GHCVHMRGLPYRATENDIYNFFSPLNPMR--VHIEIGPDGRVTGEADVEFATHEDAVAAM 345

Query: 489 CRHKQYMGNRFIQV 502
            + K  M +R++++
Sbjct: 346 AKDKANMQHRYVEL 359



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 24/72 (33%), Positives = 44/72 (61%), Gaps = 1/72 (1%)

Query: 858 IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVIDL 917
           ++++ +PF  S +EI+ FF G +++P  + L  + +G  TGEA V F S++ A  A+   
Sbjct: 113 VRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKH 172

Query: 918 NDRPIGSRKVKL 929
            +R IG R +++
Sbjct: 173 KER-IGHRYIEI 183



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 24/79 (30%), Positives = 44/79 (55%), Gaps = 2/79 (2%)

Query: 298 PINPDDLYVSVHGMPFSAMENDVRDFFHGLRV--DAVHLLKDHVGRNNGNGLVKFLSPQD 355
           P   +D +V + G+PF   + ++  FF GL +  + + L  D  GR+ G   V+F S + 
Sbjct: 105 PDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEI 164

Query: 356 TFEALKRNRMLMIQRYVEV 374
             +ALK+++  +  RY+E+
Sbjct: 165 AEKALKKHKERIGHRYIEI 183



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 24/69 (34%), Positives = 38/69 (55%)

Query: 306 VSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEALKRNRM 365
           V + G+P+ A END+ +FF  L    VH+     GR  G   V+F + +D   A+ +++ 
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDKA 350

Query: 366 LMIQRYVEV 374
            M  RYVE+
Sbjct: 351 NMQHRYVEL 359



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 24/69 (34%), Positives = 42/69 (60%), Gaps = 3/69 (4%)

Query: 848 SSSGKPGPTVIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLK--YNEKGMPTGEAMVAFE 905
           S+ G+ G  V+KV+ +P++ S DE++ FF   ++  G+  ++  Y  +G P+GEA V  E
Sbjct: 4   STEGREG-FVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELE 62

Query: 906 SRDEATAAV 914
           S +E   A+
Sbjct: 63  SEEEVKLAL 71



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 4/88 (4%)

Query: 5   IRLQGLPIVAGTMDIRHFFSGLTIPDGG----VHIVGGELGEAFIVFATDEDARLGMMRT 60
           +RL+GLP      +I  FFSGL I   G    V   G   GEAF+ FA+ E A   + + 
Sbjct: 113 VRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKH 172

Query: 61  GGTIKGSKVTLLLSSKTEMQNMIELSRR 88
              I    + +  SS+ E++   +  R+
Sbjct: 173 KERIGHRYIEIFKSSRAEVRTHYDPPRK 200



 Score = 37.0 bits (84), Expect = 0.086
 Identities = 16/54 (29%), Positives = 30/54 (55%), Gaps = 2/54 (3%)

Query: 545 CAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDA 598
           C H+  +P+  T+ D+  F    P++   VH+ +  +G+  G+A V+F   +DA
Sbjct: 290 CVHMRGLPYRATENDIYNFFS--PLNPMRVHIEIGPDGRVTGEADVEFATHEDA 341



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 22/82 (26%), Positives = 41/82 (50%), Gaps = 6/82 (7%)

Query: 4  VIRLQGLPIVAGTMDIRHFFSGLTIPDG--GVHIV----GGELGEAFIVFATDEDARLGM 57
          V++++GLP      ++  FFS   I +G  G+  +    G   GEAF+   ++E+ +L +
Sbjct: 12 VVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLAL 71

Query: 58 MRTGGTIKGSKVTLLLSSKTEM 79
           +   T+    V +  S+  EM
Sbjct: 72 KKDRETMGHRYVEVFKSNSVEM 93



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 28/79 (35%), Positives = 37/79 (46%), Gaps = 14/79 (17%)

Query: 5   IRLQGLPIVAGTMDIRHFFSGLTI--------PDGGVHIVGGELGEAFIVFATDEDARLG 56
           + ++GLP  A   DI +FFS L          PDG V       GEA + FAT EDA   
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRV------TGEADVEFATHEDAVAA 344

Query: 57  MMRTGGTIKGSKVTLLLSS 75
           M +    ++   V L L+S
Sbjct: 345 MAKDKANMQHRYVELFLNS 363


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.138    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,452,517
Number of Sequences: 37866
Number of extensions: 4087458
Number of successful extensions: 89717
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1073
Number of HSP's successfully gapped in prelim test: 1556
Number of HSP's that attempted gapping in prelim test: 21991
Number of HSP's gapped (non-prelim): 25531
length of query: 932
length of database: 18,247,518
effective HSP length: 112
effective length of query: 820
effective length of database: 14,006,526
effective search space: 11485351320
effective search space used: 11485351320
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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