Guide to the Human Genome
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Search of human proteins with 19913356

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19913356 Wolf-Hirschhorn syndrome candidate 1 protein
isoform 3 [Homo sapiens]
         (647 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19913356 Wolf-Hirschhorn syndrome candidate 1 protein isoform...  1285   0.0  
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform...  1243   0.0  
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform...  1243   0.0  
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform...  1243   0.0  
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor...  1243   0.0  
gi|6594683 Wolf-Hirschhorn syndrome candidate 1 protein isoform ...  1242   0.0  
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]               222   7e-58
gi|13699813 WHSC1L1 protein isoform short [Homo sapiens]              202   8e-52
gi|27477095 nuclear receptor binding SET domain protein 1 isofor...    99   2e-20
gi|19923586 nuclear receptor binding SET domain protein 1 isofor...    99   2e-20
gi|4504191 mutS homolog 6 [Homo sapiens]                               72   2e-12
gi|94721344 zinc finger, CW type with PWWP domain 1 [Homo sapiens]     65   1e-10
gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens]     51   4e-06
gi|194688135 high-mobility group box 2 [Homo sapiens]                  44   4e-04
gi|194688133 high-mobility group box 2 [Homo sapiens]                  44   4e-04
gi|11321591 high-mobility group box 2 [Homo sapiens]                   44   4e-04
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       44   5e-04
gi|28559065 DNA cytosine-5 methyltransferase 3 beta isoform 6 [H...    42   0.001
gi|28559063 DNA cytosine-5 methyltransferase 3 beta isoform 3 [H...    42   0.001
gi|28559061 DNA cytosine-5 methyltransferase 3 beta isoform 2 [H...    42   0.001
gi|5901940 DNA cytosine-5 methyltransferase 3 beta isoform 1 [Ho...    42   0.001
gi|115529449 upstream binding transcription factor, RNA polymera...    42   0.001
gi|115529451 upstream binding transcription factor, RNA polymera...    42   0.001
gi|7657671 upstream binding transcription factor, RNA polymerase...    42   0.001
gi|148839376 PWWP domain containing 2 isoform 1 [Homo sapiens]         42   0.001
gi|83715964 high-mobility group 20B [Homo sapiens]                     42   0.002
gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens]          42   0.002
gi|51173873 high-mobility group protein 2-like 1 [Homo sapiens]        41   0.003
gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens]             41   0.003
gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo sa...    41   0.004

>gi|19913356 Wolf-Hirschhorn syndrome candidate 1 protein isoform 3
           [Homo sapiens]
          Length = 647

 Score = 1285 bits (3325), Expect = 0.0
 Identities = 647/647 (100%), Positives = 647/647 (100%)

Query: 1   MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
           MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG
Sbjct: 1   MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60

Query: 61  VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
           VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG
Sbjct: 61  VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120

Query: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
           SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE
Sbjct: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180

Query: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
           QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV
Sbjct: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240

Query: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
           SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ
Sbjct: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300

Query: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
           APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA
Sbjct: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360

Query: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
           KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK
Sbjct: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420

Query: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
           STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG
Sbjct: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480

Query: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
           EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE
Sbjct: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540

Query: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
           AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR
Sbjct: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600

Query: 601 NRASTAASSALGFSKSSSPSASLTENELLWEPTPVKLDLNPAALYCT 647
           NRASTAASSALGFSKSSSPSASLTENELLWEPTPVKLDLNPAALYCT
Sbjct: 601 NRASTAASSALGFSKSSSPSASLTENELLWEPTPVKLDLNPAALYCT 647


>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 1243 bits (3215), Expect = 0.0
 Identities = 628/632 (99%), Positives = 629/632 (99%)

Query: 1   MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
           MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG
Sbjct: 1   MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60

Query: 61  VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
           VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG
Sbjct: 61  VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120

Query: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
           SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE
Sbjct: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180

Query: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
           QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV
Sbjct: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240

Query: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
           SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ
Sbjct: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300

Query: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
           APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA
Sbjct: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360

Query: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
           KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK
Sbjct: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420

Query: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
           STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG
Sbjct: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480

Query: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
           EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE
Sbjct: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540

Query: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
           AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR
Sbjct: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600

Query: 601 NRASTAASSALGFSKSSSPSASLTENELLWEP 632
           NRASTAASSALGFSKSSSPSASLTENE+   P
Sbjct: 601 NRASTAASSALGFSKSSSPSASLTENEVSDSP 632



 Score = 29.6 bits (65), Expect = 9.0
 Identities = 14/50 (28%), Positives = 23/50 (46%), Gaps = 2/50 (4%)

Query: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFG 268
           K +  D++W K+  Y WWP  V      +    ++  K    ++ V FFG
Sbjct: 877 KLHFQDIIWVKLGNYRWWPAEVCHPK--NVPPNIQKMKHEIGEFPVFFFG 924


>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 1243 bits (3215), Expect = 0.0
 Identities = 628/632 (99%), Positives = 629/632 (99%)

Query: 1   MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
           MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG
Sbjct: 1   MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60

Query: 61  VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
           VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG
Sbjct: 61  VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120

Query: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
           SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE
Sbjct: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180

Query: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
           QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV
Sbjct: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240

Query: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
           SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ
Sbjct: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300

Query: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
           APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA
Sbjct: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360

Query: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
           KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK
Sbjct: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420

Query: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
           STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG
Sbjct: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480

Query: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
           EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE
Sbjct: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540

Query: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
           AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR
Sbjct: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600

Query: 601 NRASTAASSALGFSKSSSPSASLTENELLWEP 632
           NRASTAASSALGFSKSSSPSASLTENE+   P
Sbjct: 601 NRASTAASSALGFSKSSSPSASLTENEVSDSP 632



 Score = 29.6 bits (65), Expect = 9.0
 Identities = 14/50 (28%), Positives = 23/50 (46%), Gaps = 2/50 (4%)

Query: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFG 268
           K +  D++W K+  Y WWP  V      +    ++  K    ++ V FFG
Sbjct: 877 KLHFQDIIWVKLGNYRWWPAEVCHPK--NVPPNIQKMKHEIGEFPVFFFG 924


>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 1243 bits (3215), Expect = 0.0
 Identities = 628/632 (99%), Positives = 629/632 (99%)

Query: 1   MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
           MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG
Sbjct: 1   MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60

Query: 61  VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
           VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG
Sbjct: 61  VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120

Query: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
           SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE
Sbjct: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180

Query: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
           QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV
Sbjct: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240

Query: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
           SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ
Sbjct: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300

Query: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
           APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA
Sbjct: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360

Query: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
           KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK
Sbjct: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420

Query: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
           STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG
Sbjct: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480

Query: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
           EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE
Sbjct: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540

Query: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
           AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR
Sbjct: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600

Query: 601 NRASTAASSALGFSKSSSPSASLTENELLWEP 632
           NRASTAASSALGFSKSSSPSASLTENE+   P
Sbjct: 601 NRASTAASSALGFSKSSSPSASLTENEVSDSP 632



 Score = 29.6 bits (65), Expect = 9.0
 Identities = 14/50 (28%), Positives = 23/50 (46%), Gaps = 2/50 (4%)

Query: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFG 268
           K +  D++W K+  Y WWP  V      +    ++  K    ++ V FFG
Sbjct: 877 KLHFQDIIWVKLGNYRWWPAEVCHPK--NVPPNIQKMKHEIGEFPVFFFG 924


>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 1243 bits (3215), Expect = 0.0
 Identities = 628/632 (99%), Positives = 629/632 (99%)

Query: 1   MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
           MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG
Sbjct: 1   MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60

Query: 61  VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
           VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG
Sbjct: 61  VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120

Query: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
           SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE
Sbjct: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180

Query: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
           QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV
Sbjct: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240

Query: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
           SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ
Sbjct: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300

Query: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
           APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA
Sbjct: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360

Query: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
           KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK
Sbjct: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420

Query: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
           STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG
Sbjct: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480

Query: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
           EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE
Sbjct: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540

Query: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
           AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR
Sbjct: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600

Query: 601 NRASTAASSALGFSKSSSPSASLTENELLWEP 632
           NRASTAASSALGFSKSSSPSASLTENE+   P
Sbjct: 601 NRASTAASSALGFSKSSSPSASLTENEVSDSP 632



 Score = 29.6 bits (65), Expect = 9.0
 Identities = 14/50 (28%), Positives = 23/50 (46%), Gaps = 2/50 (4%)

Query: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFG 268
           K +  D++W K+  Y WWP  V      +    ++  K    ++ V FFG
Sbjct: 877 KLHFQDIIWVKLGNYRWWPAEVCHPK--NVPPNIQKMKHEIGEFPVFFFG 924


>gi|6594683 Wolf-Hirschhorn syndrome candidate 1 protein isoform 4
           [Homo sapiens]
          Length = 629

 Score = 1242 bits (3214), Expect = 0.0
 Identities = 627/628 (99%), Positives = 628/628 (100%)

Query: 1   MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
           MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG
Sbjct: 1   MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60

Query: 61  VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
           VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG
Sbjct: 61  VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120

Query: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
           SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE
Sbjct: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180

Query: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
           QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV
Sbjct: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240

Query: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
           SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ
Sbjct: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300

Query: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
           APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA
Sbjct: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360

Query: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
           KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK
Sbjct: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420

Query: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
           STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG
Sbjct: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480

Query: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
           EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE
Sbjct: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540

Query: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
           AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR
Sbjct: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600

Query: 601 NRASTAASSALGFSKSSSPSASLTENEL 628
           NRASTAASSALGFSKSSSPSASLTENE+
Sbjct: 601 NRASTAASSALGFSKSSSPSASLTENEV 628


>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
          Length = 1437

 Score =  222 bits (566), Expect = 7e-58
 Identities = 171/549 (31%), Positives = 262/549 (47%), Gaps = 70/549 (12%)

Query: 111 PPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRK 170
           P    P K GSPEIKLKITKT  NG+ LFESS+CGD   +V  SE    K E++ +  RK
Sbjct: 140 PQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEVQASEHTKSKHESR-KEKRK 198

Query: 171 RSIKYDSLLEQGLVEAALVS-----------KISSPSDK--KIPAKKESCP--------- 208
           +S K+DS   +      +             ++ + S+K  + P  KE  P         
Sbjct: 199 KSNKHDSSRSEERKSHKIPKLEPEEQNRPNERVDTVSEKPREEPVLKEEAPVQPILSSVP 258

Query: 209 ----NTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHV 264
               +TG      +K+ VGDLVWSKV  YPWWPCMVS+DP L  +TK+    + AR+YHV
Sbjct: 259 TTEVSTG------VKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKIN--TRGAREYHV 310

Query: 265 QFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEM 324
           QFF + PERAW+ EK +  ++G  Q+E+L  E+ KQA   +EK K+ KP   + RAQW++
Sbjct: 311 QFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDI 370

Query: 325 GIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVAKEAGIAAESLGEMAESSGVSEEAA 384
           GI  AE+A  M+ EER  ++TF+Y+  Q       AK++  +   + +      V     
Sbjct: 371 GIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKKSVASKTEVKKTRRPRSVLNTQP 430

Query: 385 E--NPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRK 442
           E  N   V       + RR ++   ++   E  P +      KTA A  R+ + +     
Sbjct: 431 EQTNAGEVASSLSSTEIRRHSQRRHTSAEEEEPPPV--KIAWKTAAA--RKSLPASITMH 486

Query: 443 KTTVSMPRSRKGDAASQFLVFC-------QKHRDEVVAEHPDASGEEIEELLRSQWSLL- 494
           K ++ + +           VF         K  D+ V       G + E  +R Q  L+ 
Sbjct: 487 KGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYS-TKGIGNKTEISVRGQDRLII 545

Query: 495 -SEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAEAEDTPRKRLRTDK 553
            +  QR    T+ ++ +P      +G+V  K++  + R +  +E +  E  P+K+++ + 
Sbjct: 546 STPNQRNEKPTQ-SVSSPEATSGSTGSVEKKQQRRSIRTRSESEKS-TEVVPKKKIKKE- 602

Query: 554 HSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGF 613
               + +T+   T +T              Q     +SD+CKPLKKR+RAST        
Sbjct: 603 ----QVETVPQATVKTG------------LQKGASEISDSCKPLKKRSRASTDVEMTSSA 646

Query: 614 SKSSSPSAS 622
            + +S S S
Sbjct: 647 YRDTSDSDS 655



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 44/232 (18%), Positives = 88/232 (37%), Gaps = 44/232 (18%)

Query: 219  KYNVGDLVWSKVSGYPWWP---CMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAW 275
            K +   +VW K+  Y WWP   C   + PL      ++G K     + V FFG + +  W
Sbjct: 957  KLHYKQIVWVKLGNYRWWPAEICNPRSVPL-----NIQGLKHDLGDFPVFFFG-SHDYYW 1010

Query: 276  IFEKSLVAF--------EGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIV 327
            + +  +  +        EG+    K  +++ ++A  + +++K                  
Sbjct: 1011 VHQGRVFPYVEGDKSFAEGQTSINKTFKKALEEAAKRFQELK-----------------A 1053

Query: 328  QAEEAASMSVEERKAKFTFLYVGDQLHLNP-QVAKEAGIAAESLGEMAESSGVSEEAAEN 386
            Q E   ++ +E+   K          H+   +V  +  I    L E+   +   + A EN
Sbjct: 1054 QRESKEALEIEKNSRK-----PPPYKHIKANKVIGKVQIQVADLSEIPRCN--CKPADEN 1106

Query: 387  PKSVREECI--PMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVG 436
            P  +  EC+   ++     ++C + +  ++     +  P        RRG G
Sbjct: 1107 PCGLESECLNRMLQYECHPQVCPAGDRCQNQCFTKRLYPDAEIIKTERRGWG 1158


>gi|13699813 WHSC1L1 protein isoform short [Homo sapiens]
          Length = 645

 Score =  202 bits (514), Expect = 8e-52
 Identities = 155/500 (31%), Positives = 241/500 (48%), Gaps = 58/500 (11%)

Query: 111 PPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRK 170
           P    P K GSPEIKLKITKT  NG+ LFESS+CGD   +V  SE    K E++ +  RK
Sbjct: 140 PQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEVQASEHTKSKHESR-KEKRK 198

Query: 171 RSIKYDSLLEQGLVEAALVS-----------KISSPSDK--KIPAKKESCP--------- 208
           +S K+DS   +      +             ++ + S+K  + P  KE  P         
Sbjct: 199 KSNKHDSSRSEERKSHKIPKLEPEEQNRPNERVDTVSEKPREEPVLKEEAPVQPILSSVP 258

Query: 209 ----NTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHV 264
               +TG      +K+ VGDLVWSKV  YPWWPCMVS+DP L  +TK+    + AR+YHV
Sbjct: 259 TTEVSTG------VKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKIN--TRGAREYHV 310

Query: 265 QFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEM 324
           QFF + PERAW+ EK +  ++G  Q+E+L  E+ KQA   +EK K+ KP   + RAQW++
Sbjct: 311 QFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDI 370

Query: 325 GIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVAKEAGIAAESLGEMAESSGVSEEAA 384
           GI  AE+A  M+ EER  ++TF+Y+  Q       AK++  +   + +      V     
Sbjct: 371 GIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKKSVASKTEVKKTRRPRSVLNTQP 430

Query: 385 E--NPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRK 442
           E  N   V       + RR ++   ++   E  P +      KTA A  R+ + +     
Sbjct: 431 EQTNAGEVASSLSSTEIRRHSQRRHTSAEEEEPPPV--KIAWKTAAA--RKSLPASITMH 486

Query: 443 KTTVSMPRSRKGDAASQFLVFC-------QKHRDEVVAEHPDASGEEIEELLRSQWSLL- 494
           K ++ + +           VF         K  D+ V       G + E  +R Q  L+ 
Sbjct: 487 KGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYS-TKGIGNKTEISVRGQDRLII 545

Query: 495 -SEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAEAEDTPRKRLRTDK 553
            +  QR    T+ ++ +P      +G+V  K++  + R +  +E +  E  P+K+++ + 
Sbjct: 546 STPNQRNEKPTQ-SVSSPEATSGSTGSVEKKQQRRSIRTRSESEKS-TEVVPKKKIKKE- 602

Query: 554 HSLRKRDTITDKTARTSSYK 573
               + +T+   T +T   K
Sbjct: 603 ----QVETVPQATVKTGLQK 618


>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
           [Homo sapiens]
          Length = 2427

 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 52/143 (36%), Positives = 84/143 (58%), Gaps = 16/143 (11%)

Query: 193 SSPSDKKIP---AKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSY 249
           SS + +++P    KK+S P         LKY VGDL+W+K    PWWPC + +DPL++++
Sbjct: 31  SSSTSQELPFCQPKKKSTP---------LKYEVGDLIWAKFKRRPWWPCRICSDPLINTH 81

Query: 250 TKLK-GQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKI 308
           +K+K   ++  RQY+V+ FGD  ERAW+  K++V FEG  QFE+L      +   K ++ 
Sbjct: 82  SKMKVSNRRPYRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEEL---PVLRRRGKQKEK 138

Query: 309 KLLKPISGKLRAQWEMGIVQAEE 331
                +  K+ ++WE  +  AE+
Sbjct: 139 GYRHKVPQKILSKWEASVGLAEQ 161



 Score = 30.0 bits (66), Expect = 6.9
 Identities = 24/98 (24%), Positives = 43/98 (43%), Gaps = 17/98 (17%)

Query: 224  DLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVA 283
            ++VW KV  Y WWP  +     + S   +   +    ++ V FFG + +  W  +  +  
Sbjct: 1489 EIVWVKVGRYRWWPAEICHPRAVPS--NIDKMRHDVGEFPVLFFG-SNDYLWTHQARVFP 1545

Query: 284  F-EG------------EGQFEKLCQESAKQ-APTKAEK 307
            + EG            +G ++K  QE+A +    KA+K
Sbjct: 1546 YMEGDVSSKDKMGKGVDGTYKKALQEAAARFEELKAQK 1583


>gi|19923586 nuclear receptor binding SET domain protein 1 isoform b
           [Homo sapiens]
          Length = 2696

 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 52/143 (36%), Positives = 84/143 (58%), Gaps = 16/143 (11%)

Query: 193 SSPSDKKIP---AKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSY 249
           SS + +++P    KK+S P         LKY VGDL+W+K    PWWPC + +DPL++++
Sbjct: 300 SSSTSQELPFCQPKKKSTP---------LKYEVGDLIWAKFKRRPWWPCRICSDPLINTH 350

Query: 250 TKLK-GQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKI 308
           +K+K   ++  RQY+V+ FGD  ERAW+  K++V FEG  QFE+L      +   K ++ 
Sbjct: 351 SKMKVSNRRPYRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEEL---PVLRRRGKQKEK 407

Query: 309 KLLKPISGKLRAQWEMGIVQAEE 331
                +  K+ ++WE  +  AE+
Sbjct: 408 GYRHKVPQKILSKWEASVGLAEQ 430



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 55/213 (25%), Positives = 83/213 (38%), Gaps = 36/213 (16%)

Query: 24  APEILGS--ANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALP-FIPADKLK 80
           APE   S   NG++   E    C++ LS          G  Q   G D+   +IP  +L+
Sbjct: 24  APEDKDSPFGNGQSNFSEPLNGCTMQLSTVS-------GTSQNAYGQDSPSCYIPLRRLQ 76

Query: 81  DLTSRVFNGE--PGAHDAKLRFESQEMKG--IGTPPNTT---------------PIKNGS 121
           DL S + N E   G+ D    F+  E       TP   T               P  N S
Sbjct: 77  DLASMI-NVEYLNGSADGSESFQDPEKSDSRAQTPIVCTSLSPGGPTALAMKQEPSCNNS 135

Query: 122 PEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKA------RRNRKRSIKY 175
           PE+++K+TKT  NG   FE+  C D A   S+ +      E+++            +  Y
Sbjct: 136 PELQVKVTKTIKNGFLHFENFTCVDDADVDSEMDPEQPVTEDESIEEIFEETQTNATCNY 195

Query: 176 DSLLEQGLVEAALVSKISSPSDKKIPAKKESCP 208
           ++  E G+  A    + S+P  +    K    P
Sbjct: 196 ETKSENGVKVAMGSEQDSTPESRHGAVKSPFLP 228



 Score = 30.0 bits (66), Expect = 6.9
 Identities = 24/98 (24%), Positives = 43/98 (43%), Gaps = 17/98 (17%)

Query: 224  DLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVA 283
            ++VW KV  Y WWP  +     + S   +   +    ++ V FFG + +  W  +  +  
Sbjct: 1758 EIVWVKVGRYRWWPAEICHPRAVPS--NIDKMRHDVGEFPVLFFG-SNDYLWTHQARVFP 1814

Query: 284  F-EG------------EGQFEKLCQESAKQ-APTKAEK 307
            + EG            +G ++K  QE+A +    KA+K
Sbjct: 1815 YMEGDVSSKDKMGKGVDGTYKKALQEAAARFEELKAQK 1852


>gi|4504191 mutS homolog 6 [Homo sapiens]
          Length = 1360

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 48/166 (28%), Positives = 81/166 (48%), Gaps = 12/166 (7%)

Query: 220 YNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEK 279
           ++ GDLVW+K+ GYPWWPC+V   P   ++ + KG  KS R  HVQFF D+P R W+ ++
Sbjct: 90  FSPGDLVWAKMEGYPWWPCLVYNHPFDGTFIREKG--KSVR-VHVQFFDDSPTRGWVSKR 146

Query: 280 SLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAA----SM 335
            L  + G        +E+ K     + K ++L+ +     A  +  I + E A     S 
Sbjct: 147 LLKPYTGSKS-----KEAQKGGHFYSAKPEILRAMQRADEALNKDKIKRLELAVCDEPSE 201

Query: 336 SVEERKAKFTFLYVGDQLHLNPQVAKEAGIAAESLGEMAESSGVSE 381
             EE + +    YV D+   + ++  E  +  ++ G    S  + +
Sbjct: 202 PEEEEEMEVGTTYVTDKSEEDNEIESEEEVQPKTQGSRRSSRQIKK 247


>gi|94721344 zinc finger, CW type with PWWP domain 1 [Homo sapiens]
          Length = 648

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 50/193 (25%), Positives = 80/193 (41%), Gaps = 19/193 (9%)

Query: 210 TGRDKD-HLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKS-ARQYHVQFF 267
           TG + D     Y  G ++W+K  GYPWWP M+ +DP L  Y        S   +YHV FF
Sbjct: 304 TGLESDVAYASYIPGSIIWAKQYGYPWWPGMIESDPDLGEYFLFTSHLDSLPSKYHVTFF 363

Query: 268 GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIV 327
           G+   RAWI    L        F++L  E           + ++K        +  + ++
Sbjct: 364 GETVSRAWIPVNML------KNFQELSLE-----------LSVMKKRRNDCSQKLGVALM 406

Query: 328 QAEEAASMSVEERKAKFTFLYVGDQLHLNPQVAKEAGIAAESLGEMAESSGVSEEAAENP 387
            A+EA  +S++ER   F F    +  + N +          S G   E     EE  +  
Sbjct: 407 MAQEAEQISIQERVNLFGFWSRFNGSNSNGERKDLQLSGLNSPGSCLEKKEKEEELEKEE 466

Query: 388 KSVREECIPMKRR 400
               +  +P+++R
Sbjct: 467 GEKTDPILPIRKR 479


>gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens]
          Length = 240

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 56/219 (25%), Positives = 94/219 (42%), Gaps = 16/219 (7%)

Query: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFE 278
           +Y  GDLV++K+ GYP WP  +   P           K +A +Y V FFG   E A++  
Sbjct: 9   EYKCGDLVFAKMKGYPHWPARIDEMP-------EAAVKSTANKYQVFFFG-THETAFLGP 60

Query: 279 KSLVAF-EGEGQFEKLCQESA-KQAPTKAEKIKLLKPISGKLRAQWEMGIVQAE---EAA 333
           K L  + E + +F K  +     +   + E    +K  SG   +Q +  + + E   EAA
Sbjct: 61  KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVK-ASGYQSSQKKSCVEEPEPEPEAA 119

Query: 334 SMSVEER-KAKFTFLYVGDQLHLNPQVAK-EAGIAAESLGEMAESSGVSEEAAENPKSVR 391
               +++  A+ +    G  +   P   K E G      G++ E S    + AENP+   
Sbjct: 120 EGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEE 179

Query: 392 EECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEAD 430
           +E   ++  R   +     +  S P  G+  PQ+  E +
Sbjct: 180 KEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEE 218


>gi|194688135 high-mobility group box 2 [Homo sapiens]
          Length = 209

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 34/121 (28%), Positives = 51/121 (42%), Gaps = 16/121 (13%)

Query: 438 PPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEK 497
           P G KK     P + K    S F +FC +HR ++ +EHP  S  +  + L   WS  S K
Sbjct: 81  PKGDKKGKKKDPNAPKRPP-SAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAK 139

Query: 498 QRARYNTKFAL--------VAPVQAEEDS-------GNVNGKKRNHTKRIQDPTEDAEAE 542
            +  Y  K A         +A  +A+  S       G   G K+ +    ++  E+ E E
Sbjct: 140 DKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTGSKKKNEPEDEEEEEEEEDE 199

Query: 543 D 543
           D
Sbjct: 200 D 200


>gi|194688133 high-mobility group box 2 [Homo sapiens]
          Length = 209

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 34/121 (28%), Positives = 51/121 (42%), Gaps = 16/121 (13%)

Query: 438 PPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEK 497
           P G KK     P + K    S F +FC +HR ++ +EHP  S  +  + L   WS  S K
Sbjct: 81  PKGDKKGKKKDPNAPKRPP-SAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAK 139

Query: 498 QRARYNTKFAL--------VAPVQAEEDS-------GNVNGKKRNHTKRIQDPTEDAEAE 542
            +  Y  K A         +A  +A+  S       G   G K+ +    ++  E+ E E
Sbjct: 140 DKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTGSKKKNEPEDEEEEEEEEDE 199

Query: 543 D 543
           D
Sbjct: 200 D 200


>gi|11321591 high-mobility group box 2 [Homo sapiens]
          Length = 209

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 34/121 (28%), Positives = 51/121 (42%), Gaps = 16/121 (13%)

Query: 438 PPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEK 497
           P G KK     P + K    S F +FC +HR ++ +EHP  S  +  + L   WS  S K
Sbjct: 81  PKGDKKGKKKDPNAPKRPP-SAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAK 139

Query: 498 QRARYNTKFAL--------VAPVQAEEDS-------GNVNGKKRNHTKRIQDPTEDAEAE 542
            +  Y  K A         +A  +A+  S       G   G K+ +    ++  E+ E E
Sbjct: 140 DKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTGSKKKNEPEDEEEEEEEEDE 199

Query: 543 D 543
           D
Sbjct: 200 D 200


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 117/615 (19%), Positives = 233/615 (37%), Gaps = 64/615 (10%)

Query: 19  IKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPA-- 76
           ++ KQ  E LG     T   EVN + SV   +A+ +++  +       G D   F+    
Sbjct: 50  LRQKQEEESLGQV---TDQVEVNAQNSVPDEEAKTTTTNTQ-----VEGDDEAAFLERLA 101

Query: 77  -------DKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPI--KNGSPEIKLK 127
                   +L++   R    +P   DA L   S+ M+       TT    K+ S + + +
Sbjct: 102 RREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYE 161

Query: 128 ITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLEQGLVEAA 187
           I +T    K  ++ +   D+  +  + +E  ++ E K +R      + + ++E+   E+ 
Sbjct: 162 IEETETVTKS-YQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQ 220

Query: 188 LVSKISSPSDKKIPA---KKESCPNTGRDK-DHLLKYNVGD-----LVWSKVSGYPWWPC 238
             + + S  + +I +   K+E     G D+  H  K    D        +++        
Sbjct: 221 EETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERI 280

Query: 239 MVSADP-LLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQES 297
               D  +     +++ ++K+A Q   +   +A ER  + E+   A E   + +    E 
Sbjct: 281 KAEQDKKIADERARIEAEEKAAAQERER--REAEERERMREEEKRAAEERQRIK----EE 334

Query: 298 AKQAPTKAEKIKL--LKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHL 355
            K+A  + ++IK    +    + R + E      E   + + EE KAK        QL  
Sbjct: 335 EKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEE 394

Query: 356 NPQVAKEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESH 415
                +E  I  E + +  E   V+E+ A+  K            +  K+ +  E L+  
Sbjct: 395 KKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQED 454

Query: 416 PDIGKSTPQKTA----EADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEV 471
               K    K      + +P+  V S   RKK    + +S+ G+    F+    KH +  
Sbjct: 455 KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV-KSQNGE----FMTHKLKHTENT 509

Query: 472 VAEHPDASGEEIEELLRSQW----SLLSEKQRARYNTKFALVAPVQAEEDSGNVN----G 523
            +     +  + +E   +        L E +R R  T+      ++ ++    +      
Sbjct: 510 FSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELK 569

Query: 524 KKRNHTKRIQDPTEDAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKS 583
           KKR   +++ +  E    ++   ++LR ++   R ++ I  + A          A+  + 
Sbjct: 570 KKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAE---------AAEKRQ 620

Query: 584 QAATKNLSDACKPLK 598
           +     LSD  KP K
Sbjct: 621 KMPEDGLSDDKKPFK 635


>gi|28559065 DNA cytosine-5 methyltransferase 3 beta isoform 6 [Homo
           sapiens]
          Length = 845

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 6/51 (11%)

Query: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGD 269
           ++ +GDLVW K+ G+ WWP MV +         + G +       VQ+FGD
Sbjct: 234 EFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMR------WVQWFGD 278


>gi|28559063 DNA cytosine-5 methyltransferase 3 beta isoform 3 [Homo
           sapiens]
          Length = 770

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 6/51 (11%)

Query: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGD 269
           ++ +GDLVW K+ G+ WWP MV +         + G +       VQ+FGD
Sbjct: 222 EFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMR------WVQWFGD 266


>gi|28559061 DNA cytosine-5 methyltransferase 3 beta isoform 2 [Homo
           sapiens]
          Length = 833

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 6/51 (11%)

Query: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGD 269
           ++ +GDLVW K+ G+ WWP MV +         + G +       VQ+FGD
Sbjct: 222 EFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMR------WVQWFGD 266


>gi|5901940 DNA cytosine-5 methyltransferase 3 beta isoform 1 [Homo
           sapiens]
          Length = 853

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 6/51 (11%)

Query: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGD 269
           ++ +GDLVW K+ G+ WWP MV +         + G +       VQ+FGD
Sbjct: 222 EFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMR------WVQWFGD 266


>gi|115529449 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 32/124 (25%), Positives = 57/124 (45%), Gaps = 7/124 (5%)

Query: 458 SQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEED 517
           S   +F ++ R ++  E P+ S  E+  LL   W+ LSEK++A+Y  + A +   Q+E  
Sbjct: 375 SAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAAL-KAQSERK 433

Query: 518 SGNVNGKKRNHTKRIQDPTEDAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEA 577
            G   G++    K  + P     AE+  ++ +  D  +  K D +    A   ++  ME 
Sbjct: 434 PG---GEREERGKLPESP---KRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEK 487

Query: 578 ASSL 581
              L
Sbjct: 488 KEKL 491


>gi|115529451 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 32/124 (25%), Positives = 57/124 (45%), Gaps = 7/124 (5%)

Query: 458 SQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEED 517
           S   +F ++ R ++  E P+ S  E+  LL   W+ LSEK++A+Y  + A +   Q+E  
Sbjct: 375 SAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAAL-KAQSERK 433

Query: 518 SGNVNGKKRNHTKRIQDPTEDAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEA 577
            G   G++    K  + P     AE+  ++ +  D  +  K D +    A   ++  ME 
Sbjct: 434 PG---GEREERGKLPESP---KRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEK 487

Query: 578 ASSL 581
              L
Sbjct: 488 KEKL 491


>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 32/124 (25%), Positives = 57/124 (45%), Gaps = 7/124 (5%)

Query: 458 SQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEED 517
           S   +F ++ R ++  E P+ S  E+  LL   W+ LSEK++A+Y  + A +   Q+E  
Sbjct: 412 SAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAAL-KAQSERK 470

Query: 518 SGNVNGKKRNHTKRIQDPTEDAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEA 577
            G   G++    K  + P     AE+  ++ +  D  +  K D +    A   ++  ME 
Sbjct: 471 PG---GEREERGKLPESP---KRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEK 524

Query: 578 ASSL 581
              L
Sbjct: 525 KEKL 528



 Score = 34.7 bits (78), Expect = 0.28
 Identities = 48/216 (22%), Positives = 83/216 (38%), Gaps = 13/216 (6%)

Query: 439 PGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQ 498
           P + K     P   K      F  F +K R +    HP+ S  ++ ++L  ++  L EK+
Sbjct: 99  PYKGKKLKKHPDFPKKPLTPYFRFFMEK-RAKYAKLHPEMSNLDLTKILSKKYKELPEKK 157

Query: 499 RARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQD--PTEDAEAEDTPRKRLRT--DKH 554
           + +Y   F      + +E   N+   + +H   IQ+   ++  E   TP++   T   K 
Sbjct: 158 KMKYIQDFQR----EKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKV 213

Query: 555 SLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFS 614
            L+ R   T K  + S  K     S  K         +  K  ++  R        L  S
Sbjct: 214 YLKVRPDATTKEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNIS 273

Query: 615 KSSSPSASLTENEL----LWEPTPVKLDLNPAALYC 646
           +     ++LT+ E      ++  P K   N  +LYC
Sbjct: 274 EEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYC 309


>gi|148839376 PWWP domain containing 2 isoform 1 [Homo sapiens]
          Length = 590

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 15/100 (15%)

Query: 222 VGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSL 281
           VGD+VW K+ G+PWWP  V    L  S  + +  + S R+  V +FG +P  +++    L
Sbjct: 490 VGDIVWGKIHGFPWWPARV----LDISLGQKEDGEPSWREAKVSWFG-SPTTSFLSISKL 544

Query: 282 VAF----------EGEGQFEKLCQESAKQAPTKAEKIKLL 311
             F          + +G + K   E+A  A   A +I+ L
Sbjct: 545 SPFSEFFKLRFNRKKKGMYRKAITEAANAARHVAPEIREL 584


>gi|83715964 high-mobility group 20B [Homo sapiens]
          Length = 317

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 2/75 (2%)

Query: 428 EADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELL 487
           E +P +  G P G+K+  + +P   K      ++ F  + R+++   HPD    EI ++L
Sbjct: 47  EEEPVKKRGWPKGKKRKKI-LPNGPKAPVTG-YVRFLNERREQIRTRHPDLPFPEITKML 104

Query: 488 RSQWSLLSEKQRARY 502
            ++WS L   ++ RY
Sbjct: 105 GAEWSKLQPTEKQRY 119


>gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens]
          Length = 553

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 49/186 (26%), Positives = 81/186 (43%), Gaps = 20/186 (10%)

Query: 222 VGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSL 281
           +GDLVW K+  YP WP  +   P      K +G+K     + V+FFG   + AWI  + L
Sbjct: 8   LGDLVWGKLGRYPPWPGKIVNPP--KDLKKPRGKK----CFFVKFFG-TEDHAWIKVEQL 60

Query: 282 VAFEGEGQFEKLCQESAKQAPTKAEKI-KLLKPISGKLRAQWEMGIVQAEEAASMSVEER 340
             +    + E +     K+     + + + L+   GK   Q        ++    S EER
Sbjct: 61  KPYHAHKE-EMIKINKGKRFQQAVDAVEEFLRRAKGK--DQTSSHNSSDDKNRRNSSEER 117

Query: 341 KAKFTFLYVGDQLHLNPQVAKEAGIAAESLGEMAE--SSGVSEEAAENPKSVREECIPMK 398
               +    GD+     +++   G   +++GE  +  SSG SE  +++P    +E  P K
Sbjct: 118 SRPNS----GDE---KRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRK 170

Query: 399 RRRRAK 404
           R R  K
Sbjct: 171 RGRPPK 176


>gi|51173873 high-mobility group protein 2-like 1 [Homo sapiens]
          Length = 601

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 28/110 (25%), Positives = 44/110 (40%), Gaps = 13/110 (11%)

Query: 415 HPDIGKSTPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAE 474
           H D      +K  E D  R  G  P +K               S + VFC+++R  +VA+
Sbjct: 382 HTDGHSEKKKKKEEKDKERERGEKPKKKNM-------------SAYQVFCKEYRVTIVAD 428

Query: 475 HPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGK 524
           HP     E+ + L   W  L EK +  +  K   +   Q + ++  V  K
Sbjct: 429 HPGIDFGELSKKLAEVWKQLPEKDKLIWKQKAQYLQHKQNKAEATTVKRK 478


>gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens]
          Length = 879

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 28/111 (25%), Positives = 46/111 (41%), Gaps = 6/111 (5%)

Query: 438 PPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEK 497
           P G KK     P + K    + FL FC ++R ++  EHP  S +++ + L   W+  +  
Sbjct: 755 PKGEKKKKFKDPNAPKRPPLAFFL-FCSEYRPKIKGEHPGLSIDDVVKKLAGMWNNTAAA 813

Query: 498 QRARYNTKFALV-----APVQAEEDSGNVNGKKRNHTKRIQDPTEDAEAED 543
            +  Y  K A +       + A    G  N  K+   K  +   +  E ED
Sbjct: 814 DKQFYEKKAAKLKEKYKKDIAAYRAKGKPNSAKKRVVKAEKSKKKKEEEED 864


>gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo
           sapiens]
          Length = 941

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 17/54 (31%), Positives = 28/54 (51%)

Query: 449 PRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRARY 502
           P  R     + FL+FC++HR  V  EHP        ++L   W++L  K++ +Y
Sbjct: 76  PEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKY 129


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.126    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,024,054
Number of Sequences: 37866
Number of extensions: 1135137
Number of successful extensions: 3893
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 98
Number of HSP's successfully gapped in prelim test: 139
Number of HSP's that attempted gapping in prelim test: 3619
Number of HSP's gapped (non-prelim): 416
length of query: 647
length of database: 18,247,518
effective HSP length: 109
effective length of query: 538
effective length of database: 14,120,124
effective search space: 7596626712
effective search space used: 7596626712
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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