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Search of human proteins with 197927454
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|197927454 DEK oncogene isoform 2 [Homo sapiens]
(341 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|197927454 DEK oncogene isoform 2 [Homo sapiens] 674 0.0
gi|4503249 DEK oncogene isoform 1 [Homo sapiens] 656 0.0
gi|4557509 cylicin 2 [Homo sapiens] 60 4e-09
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 60 4e-09
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 60 4e-09
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 59 8e-09
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 57 2e-08
gi|104526627 triadin [Homo sapiens] 57 2e-08
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 57 2e-08
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 57 3e-08
gi|221219020 NYD-SP11 protein [Homo sapiens] 56 4e-08
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 55 7e-08
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 55 7e-08
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 55 7e-08
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 55 7e-08
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 55 9e-08
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 55 9e-08
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 55 1e-07
gi|55741677 SET domain containing 1A [Homo sapiens] 55 1e-07
gi|168229156 NFKB activating protein [Homo sapiens] 54 2e-07
gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens] 54 2e-07
gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens] 54 2e-07
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 54 2e-07
gi|224591430 Ly1 antibody reactive homolog [Homo sapiens] 54 2e-07
gi|8923398 Ly1 antibody reactive homolog [Homo sapiens] 54 2e-07
gi|153791492 eukaryotic translation initiation factor 3, subunit... 54 3e-07
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi... 54 3e-07
gi|83700233 eukaryotic translation initiation factor 3, subunit ... 54 3e-07
gi|4503525 eukaryotic translation initiation factor 3, subunit C... 54 3e-07
gi|122937227 U2-associated SR140 protein [Homo sapiens] 53 3e-07
>gi|197927454 DEK oncogene isoform 2 [Homo sapiens]
Length = 341
Score = 674 bits (1738), Expect = 0.0
Identities = 341/341 (100%), Positives = 341/341 (100%)
Query: 1 MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERI 60
MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERI
Sbjct: 1 MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERI 60
Query: 61 HFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRN 120
HFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRN
Sbjct: 61 HFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRN 120
Query: 121 AMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMA 180
AMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMA
Sbjct: 121 AMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMA 180
Query: 181 RKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSK 240
RKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSK
Sbjct: 181 RKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSK 240
Query: 241 KSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLA 300
KSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLA
Sbjct: 241 KSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLA 300
Query: 301 SANLEEVTMKQICKKVYENYPTYDLTERKDFIKTTVKELIS 341
SANLEEVTMKQICKKVYENYPTYDLTERKDFIKTTVKELIS
Sbjct: 301 SANLEEVTMKQICKKVYENYPTYDLTERKDFIKTTVKELIS 341
>gi|4503249 DEK oncogene isoform 1 [Homo sapiens]
Length = 375
Score = 656 bits (1693), Expect = 0.0
Identities = 341/375 (90%), Positives = 341/375 (90%), Gaps = 34/375 (9%)
Query: 1 MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEK------------ 48
MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEK
Sbjct: 1 MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREK 60
Query: 49 ----------------------GKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTV 86
GKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTV
Sbjct: 61 KKVERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTV 120
Query: 87 SSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRIL 146
SSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRIL
Sbjct: 121 SSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRIL 180
Query: 147 NFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNK 206
NFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNK
Sbjct: 181 NFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNK 240
Query: 207 EESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE 266
EESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE
Sbjct: 241 EESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE 300
Query: 267 SESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLT 326
SESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLT
Sbjct: 301 SESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLT 360
Query: 327 ERKDFIKTTVKELIS 341
ERKDFIKTTVKELIS
Sbjct: 361 ERKDFIKTTVKELIS 375
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 59.7 bits (143), Expect = 4e-09
Identities = 53/208 (25%), Positives = 91/208 (43%), Gaps = 15/208 (7%)
Query: 102 EKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPK 161
E+ SV + + LK R + S + ++ + G + K + K GK K
Sbjct: 86 ERPSVYLAARRQPLKPTRTVEVDS--KAAEIGKKGEDKTTQKDTTDSESELK-QGKKDSK 142
Query: 162 SKKTCSKGSKKERNSSGMARKAKRT------KCPEILSDESSSDEDEKKNKEESSDDEDK 215
K KG +++ ++ ++K K+ E ++ + +D KK+K++S+ +D
Sbjct: 143 KGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDS 202
Query: 216 ESEEEPPKK-TAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSD 274
+E E K T K K +K + K K S KAD + + + K ES+D+
Sbjct: 203 ATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKK 262
Query: 275 DEPLIKKLKK-----PPTDEELKETIKK 297
D IKK KK TD + K+ +KK
Sbjct: 263 DAKEIKKGKKDKKKPSSTDSDSKDDVKK 290
Score = 50.4 bits (119), Expect = 2e-06
Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 11/136 (8%)
Query: 162 SKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEP 221
++K KG K + A + + K E DED KK+ + + +D + + +
Sbjct: 213 TEKDSKKGKKDSKKGKDSAIELQAVKADE------KKDEDGKKDANKGDESKDAKKDAKE 266
Query: 222 PKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKK 281
KK K +K S SK VK K++ TK + +KK++E E S+D + KK
Sbjct: 267 IKKGKKDKKKPSSTDSDSKDDVK----KESKKDATKDAKKVAKKDTEKE-SADSKKDAKK 321
Query: 282 LKKPPTDEELKETIKK 297
K ++ K+ KK
Sbjct: 322 NAKKDAKKDAKKNAKK 337
Score = 50.1 bits (118), Expect = 3e-06
Identities = 35/145 (24%), Positives = 65/145 (44%), Gaps = 10/145 (6%)
Query: 153 KPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDD 212
K S K K +KK++ S + + E ++ +++D KK K++S
Sbjct: 172 KDSATESEDEKGGAKKDNKKDKKDSNKGKDS----ATESEGEKGGTEKDSKKGKKDSKKG 227
Query: 213 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDS 272
+D E + K K+++ +K +K +S + K D+ KK + KK S ++
Sbjct: 228 KDSAIELQAVKADEKKDEDGKKDANKGDESKDA----KKDAKEIKKGKKDKKKPSSTDSD 283
Query: 273 SDDEPLIKKLKKPPTDEELKETIKK 297
S D+ +KK K ++ K+ KK
Sbjct: 284 SKDD--VKKESKKDATKDAKKVAKK 306
Score = 45.8 bits (107), Expect = 5e-05
Identities = 63/268 (23%), Positives = 100/268 (37%), Gaps = 33/268 (12%)
Query: 13 TPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDEL 72
T T K E+ E+ ++D D E E ++ K K K K E
Sbjct: 102 TRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSK------------KGKDIEK 149
Query: 73 RNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEV--- 129
KL + G+ S E KK + KK N S E
Sbjct: 150 GKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGE 209
Query: 130 -----LDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKG--SKKERNSSGMARK 182
D ++ +S+ K L K K KK +KG SK + + +K
Sbjct: 210 KGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKK 269
Query: 183 AKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSK--SK 240
K+ K +D S D+ +K++K++++ D KK AK++ K+ A SK +K
Sbjct: 270 GKKDKKKPSSTDSDSKDDVKKESKKDATKDA---------KKVAKKDTEKESADSKKDAK 320
Query: 241 KSVKSANVKKADSSTTKKNQNSSKKESE 268
K+ K K A + K + +KK+ +
Sbjct: 321 KNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 59.7 bits (143), Expect = 4e-09
Identities = 60/251 (23%), Positives = 111/251 (44%), Gaps = 39/251 (15%)
Query: 18 ASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDELRNLHK 77
+S+ EPE R + EE+ DEE + + + +++ + R H+
Sbjct: 1253 SSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDS-----------DSEESKKPRYRHR 1301
Query: 78 LLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGV 137
LL ++ TVS G E+ + K+ +E+ + R + E D + SGV
Sbjct: 1302 LLRHKL-TVSD---------GESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGV 1351
Query: 138 NSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESS 197
+ E+ + + +P +S +K ++ E N +K KR + I E S
Sbjct: 1352 SEEVSES--------EDEQRPRTRS----AKKAELEENQRSYKQKKKRRR---IKVQEDS 1396
Query: 198 SDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTK 257
S E++ ++EE + E++E EEE ++ + E K+ K +K ++ + K D T
Sbjct: 1397 SSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIR--KILKDDKLRT- 1453
Query: 258 KNQNSSKKESE 268
+ QN+ K+E E
Sbjct: 1454 ETQNALKEEEE 1464
Score = 48.5 bits (114), Expect = 8e-06
Identities = 48/192 (25%), Positives = 86/192 (44%), Gaps = 26/192 (13%)
Query: 159 LPKSKKTCSKG-SKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKN--KEESSDDEDK 215
L + K T S G S +E+ + K + + +S E S D D +++ EE S+ ED
Sbjct: 1302 LLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESED- 1360
Query: 216 ESEEEPPKKTAKR-EKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSD 274
E+ P ++AK+ E + + + K KK + V++ SS K N ++E E E+ +
Sbjct: 1361 --EQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEE 1418
Query: 275 DEPL----------------IKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYE 318
+E KK++K D++L+ + L EE K+I ++ E
Sbjct: 1419 EEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKE---EEERRKRIAERERE 1475
Query: 319 NYPTYDLTERKD 330
++ E +D
Sbjct: 1476 REKLREVIEIED 1487
Score = 48.1 bits (113), Expect = 1e-05
Identities = 70/322 (21%), Positives = 122/322 (37%), Gaps = 35/322 (10%)
Query: 26 PGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERI-HFFLSKKKTDELRNLHKLLYNRPG 84
P +S++ E D + +E L E+ R+ H S +E+ HK LY+
Sbjct: 675 PNKLPKSKQSETVDQNSDSDEMLAI---LKEVSRMSHSSSSDTDINEIHTNHKTLYDLKT 731
Query: 85 TVSS----LKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSE 140
+K SG F+ + K + KK R +S S +SE
Sbjct: 732 QAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSES---------SNYDSE 782
Query: 141 LVKRI--LNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSS 198
L K I ++ + + + K +P +K S +K + K K S E SS
Sbjct: 783 LEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKT----SQEGSS 838
Query: 199 DEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKS----------KKSVKSANV 248
D+ E+K + E+ + +++ + PK++ S S ++S S V
Sbjct: 839 DDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEV 898
Query: 249 KKADSSTTKKNQNSSKKESESEDSSDD--EPLIKKLKKPPTDEELKETIKKLLASANLEE 306
+K + K +K + +D D E +KK + T E+ K+ KK
Sbjct: 899 RKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPS 958
Query: 307 VTMKQICKKVYENYPTYDLTER 328
K++ K + + D TE+
Sbjct: 959 DFKKKVIKMEQQYESSSDGTEK 980
Score = 42.4 bits (98), Expect = 6e-04
Identities = 68/294 (23%), Positives = 118/294 (40%), Gaps = 44/294 (14%)
Query: 29 REESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSS 88
+++ +E EDD+++ + KG +K KK +D + + K+ +
Sbjct: 932 KKDQSDETSEDDKKQSK--KGTEEK------------KKPSDFKKKVIKMEQQYESSSDG 977
Query: 89 LKKNVGQFSGFPFEKGSVQYKKK----EEMLKKFRNAMLKSICEVLDLERSGV------- 137
+K + F KG Q K E+ KK R+ K E+ D
Sbjct: 978 TEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCD 1037
Query: 138 NSELVKRILNFLMHPKPSGKPLPKS---KKTCS-----KGSKKERNSSGMARKAKRTKCP 189
+SE K K K L KS ++ CS K S KE + ++ KR +
Sbjct: 1038 SSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELR 1097
Query: 190 EILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVK 249
E + S + E ++ SSD E ES E+ KK KQ+ +SK K + +
Sbjct: 1098 ERRNLSSKRNTKEIQSGSSSSDAE--ESSEDNKKK-------KQRTSSKKKAVIVKEKKR 1148
Query: 250 KADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASAN 303
+ ++TK+ Q S S+ DD+ I + ++++K + L+ S++
Sbjct: 1149 NSLRTSTKRKQADITSSSSSDIEDDDQNSIG--EGSSDEQKIKPVTENLVLSSH 1200
Score = 38.5 bits (88), Expect = 0.009
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 6/65 (9%)
Query: 9 EGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKK 68
E + + SE+E E EE EEEE+E++E+E ++ K G+ +I +I K
Sbjct: 1394 EDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKI------LK 1447
Query: 69 TDELR 73
D+LR
Sbjct: 1448 DDKLR 1452
Score = 35.8 bits (81), Expect = 0.057
Identities = 31/133 (23%), Positives = 56/133 (42%), Gaps = 14/133 (10%)
Query: 186 TKCPEILSDESSSDEDEKKN----------KEESSDDEDKESEEEPP--KKTAKREKPKQ 233
+K + D+ D D + K S DED S++EP KK ++ +
Sbjct: 1213 SKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEEN 1272
Query: 234 KATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKE 293
++K V S + +DS +KK + + SD E +K KP +E+K
Sbjct: 1273 PGDEEAKNQVNSES--DSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKG 1330
Query: 294 TIKKLLASANLEE 306
++ ++S + E+
Sbjct: 1331 RNRRKVSSEDSED 1343
Score = 35.8 bits (81), Expect = 0.057
Identities = 31/138 (22%), Positives = 50/138 (36%), Gaps = 13/138 (9%)
Query: 169 GSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKR 228
GS + G R K+ +E + ++E KN+ S D D E ++P +
Sbjct: 1252 GSSDDEPEEGKKRTGKQ--------NEENPGDEEAKNQVNSESDSDSEESKKP---RYRH 1300
Query: 229 EKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTD 288
+ K T +S + K + K +SEDS E + + D
Sbjct: 1301 RLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESED 1360
Query: 289 EELKETIKKLLASANLEE 306
E+ T + A LEE
Sbjct: 1361 EQRPRT--RSAKKAELEE 1376
Score = 35.8 bits (81), Expect = 0.057
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 10/48 (20%)
Query: 16 QPASEKEPEMPGPREESEEEEDEDDEEEEEEEK----------GKGQK 53
Q S E + EE E+EE+E++EEEEEEE+ GKG+K
Sbjct: 1393 QEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRK 1440
Score = 29.3 bits (64), Expect = 5.3
Identities = 46/230 (20%), Positives = 82/230 (35%), Gaps = 17/230 (7%)
Query: 85 TVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSEL--- 141
T +++ + +F + + K LK F++ + L LE +NSE
Sbjct: 324 TTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEED-LNSEFRAM 382
Query: 142 --VKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSD 199
V + N H K K++K + ++++ S K R + ++
Sbjct: 383 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT 442
Query: 200 EDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKS------ANVKKADS 253
E+++ NK + + + +EEP + A + SV + S
Sbjct: 443 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS 502
Query: 254 STTKKNQNSSKKESESEDSSDDEPLIKK-----LKKPPTDEELKETIKKL 298
S + SS E E E SS + K +K T + KE KL
Sbjct: 503 SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKL 552
Score = 28.5 bits (62), Expect = 9.1
Identities = 28/119 (23%), Positives = 48/119 (40%), Gaps = 12/119 (10%)
Query: 195 ESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSS 254
+ +SD + E S E+ + P KT +P ++ + ++N + +
Sbjct: 593 QENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRP-------TETNPVTSNSDEECNE 645
Query: 255 TTKKNQNSS-----KKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVT 308
T K+ Q S K + S DS+ D P KL K E + + A L+EV+
Sbjct: 646 TVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVS 704
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 59.7 bits (143), Expect = 4e-09
Identities = 60/251 (23%), Positives = 111/251 (44%), Gaps = 39/251 (15%)
Query: 18 ASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDELRNLHK 77
+S+ EPE R + EE+ DEE + + + +++ + R H+
Sbjct: 1291 SSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDS-----------DSEESKKPRYRHR 1339
Query: 78 LLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGV 137
LL ++ TVS G E+ + K+ +E+ + R + E D + SGV
Sbjct: 1340 LLRHKL-TVSD---------GESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGV 1389
Query: 138 NSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESS 197
+ E+ + + +P +S +K ++ E N +K KR + I E S
Sbjct: 1390 SEEVSES--------EDEQRPRTRS----AKKAELEENQRSYKQKKKRRR---IKVQEDS 1434
Query: 198 SDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTK 257
S E++ ++EE + E++E EEE ++ + E K+ K +K ++ + K D T
Sbjct: 1435 SSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIR--KILKDDKLRT- 1491
Query: 258 KNQNSSKKESE 268
+ QN+ K+E E
Sbjct: 1492 ETQNALKEEEE 1502
Score = 48.5 bits (114), Expect = 8e-06
Identities = 48/192 (25%), Positives = 86/192 (44%), Gaps = 26/192 (13%)
Query: 159 LPKSKKTCSKG-SKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKN--KEESSDDEDK 215
L + K T S G S +E+ + K + + +S E S D D +++ EE S+ ED
Sbjct: 1340 LLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESED- 1398
Query: 216 ESEEEPPKKTAKR-EKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSD 274
E+ P ++AK+ E + + + K KK + V++ SS K N ++E E E+ +
Sbjct: 1399 --EQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEE 1456
Query: 275 DEPL----------------IKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYE 318
+E KK++K D++L+ + L EE K+I ++ E
Sbjct: 1457 EEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKE---EEERRKRIAERERE 1513
Query: 319 NYPTYDLTERKD 330
++ E +D
Sbjct: 1514 REKLREVIEIED 1525
Score = 48.1 bits (113), Expect = 1e-05
Identities = 70/322 (21%), Positives = 122/322 (37%), Gaps = 35/322 (10%)
Query: 26 PGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERI-HFFLSKKKTDELRNLHKLLYNRPG 84
P +S++ E D + +E L E+ R+ H S +E+ HK LY+
Sbjct: 713 PNKLPKSKQSETVDQNSDSDEMLAI---LKEVSRMSHSSSSDTDINEIHTNHKTLYDLKT 769
Query: 85 TVSS----LKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSE 140
+K SG F+ + K + KK R +S S +SE
Sbjct: 770 QAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSES---------SNYDSE 820
Query: 141 LVKRI--LNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSS 198
L K I ++ + + + K +P +K S +K + K K S E SS
Sbjct: 821 LEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKT----SQEGSS 876
Query: 199 DEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKS----------KKSVKSANV 248
D+ E+K + E+ + +++ + PK++ S S ++S S V
Sbjct: 877 DDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEV 936
Query: 249 KKADSSTTKKNQNSSKKESESEDSSDD--EPLIKKLKKPPTDEELKETIKKLLASANLEE 306
+K + K +K + +D D E +KK + T E+ K+ KK
Sbjct: 937 RKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPS 996
Query: 307 VTMKQICKKVYENYPTYDLTER 328
K++ K + + D TE+
Sbjct: 997 DFKKKVIKMEQQYESSSDGTEK 1018
Score = 42.4 bits (98), Expect = 6e-04
Identities = 68/294 (23%), Positives = 118/294 (40%), Gaps = 44/294 (14%)
Query: 29 REESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSS 88
+++ +E EDD+++ + KG +K KK +D + + K+ +
Sbjct: 970 KKDQSDETSEDDKKQSK--KGTEEK------------KKPSDFKKKVIKMEQQYESSSDG 1015
Query: 89 LKKNVGQFSGFPFEKGSVQYKKK----EEMLKKFRNAMLKSICEVLDLERSGV------- 137
+K + F KG Q K E+ KK R+ K E+ D
Sbjct: 1016 TEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCD 1075
Query: 138 NSELVKRILNFLMHPKPSGKPLPKS---KKTCS-----KGSKKERNSSGMARKAKRTKCP 189
+SE K K K L KS ++ CS K S KE + ++ KR +
Sbjct: 1076 SSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELR 1135
Query: 190 EILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVK 249
E + S + E ++ SSD E ES E+ KK KQ+ +SK K + +
Sbjct: 1136 ERRNLSSKRNTKEIQSGSSSSDAE--ESSEDNKKK-------KQRTSSKKKAVIVKEKKR 1186
Query: 250 KADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASAN 303
+ ++TK+ Q S S+ DD+ I + ++++K + L+ S++
Sbjct: 1187 NSLRTSTKRKQADITSSSSSDIEDDDQNSIG--EGSSDEQKIKPVTENLVLSSH 1238
Score = 38.5 bits (88), Expect = 0.009
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 6/65 (9%)
Query: 9 EGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKK 68
E + + SE+E E EE EEEE+E++E+E ++ K G+ +I +I K
Sbjct: 1432 EDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKI------LK 1485
Query: 69 TDELR 73
D+LR
Sbjct: 1486 DDKLR 1490
Score = 35.8 bits (81), Expect = 0.057
Identities = 31/133 (23%), Positives = 56/133 (42%), Gaps = 14/133 (10%)
Query: 186 TKCPEILSDESSSDEDEKKN----------KEESSDDEDKESEEEPP--KKTAKREKPKQ 233
+K + D+ D D + K S DED S++EP KK ++ +
Sbjct: 1251 SKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEEN 1310
Query: 234 KATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKE 293
++K V S + +DS +KK + + SD E +K KP +E+K
Sbjct: 1311 PGDEEAKNQVNSES--DSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKG 1368
Query: 294 TIKKLLASANLEE 306
++ ++S + E+
Sbjct: 1369 RNRRKVSSEDSED 1381
Score = 35.8 bits (81), Expect = 0.057
Identities = 31/138 (22%), Positives = 50/138 (36%), Gaps = 13/138 (9%)
Query: 169 GSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKR 228
GS + G R K+ +E + ++E KN+ S D D E ++P +
Sbjct: 1290 GSSDDEPEEGKKRTGKQ--------NEENPGDEEAKNQVNSESDSDSEESKKP---RYRH 1338
Query: 229 EKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTD 288
+ K T +S + K + K +SEDS E + + D
Sbjct: 1339 RLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESED 1398
Query: 289 EELKETIKKLLASANLEE 306
E+ T + A LEE
Sbjct: 1399 EQRPRT--RSAKKAELEE 1414
Score = 35.8 bits (81), Expect = 0.057
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 10/48 (20%)
Query: 16 QPASEKEPEMPGPREESEEEEDEDDEEEEEEEK----------GKGQK 53
Q S E + EE E+EE+E++EEEEEEE+ GKG+K
Sbjct: 1431 QEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRK 1478
Score = 29.3 bits (64), Expect = 5.3
Identities = 46/230 (20%), Positives = 82/230 (35%), Gaps = 17/230 (7%)
Query: 85 TVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSEL--- 141
T +++ + +F + + K LK F++ + L LE +NSE
Sbjct: 362 TTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEED-LNSEFRAM 420
Query: 142 --VKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSD 199
V + N H K K++K + ++++ S K R + ++
Sbjct: 421 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT 480
Query: 200 EDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKS------ANVKKADS 253
E+++ NK + + + +EEP + A + SV + S
Sbjct: 481 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS 540
Query: 254 STTKKNQNSSKKESESEDSSDDEPLIKK-----LKKPPTDEELKETIKKL 298
S + SS E E E SS + K +K T + KE KL
Sbjct: 541 SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKL 590
Score = 28.5 bits (62), Expect = 9.1
Identities = 28/119 (23%), Positives = 48/119 (40%), Gaps = 12/119 (10%)
Query: 195 ESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSS 254
+ +SD + E S E+ + P KT +P ++ + ++N + +
Sbjct: 631 QENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRP-------TETNPVTSNSDEECNE 683
Query: 255 TTKKNQNSS-----KKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVT 308
T K+ Q S K + S DS+ D P KL K E + + A L+EV+
Sbjct: 684 TVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVS 742
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 58.5 bits (140), Expect = 8e-09
Identities = 65/295 (22%), Positives = 118/295 (40%), Gaps = 44/295 (14%)
Query: 20 EKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHF-------FLSKKKTDEL 72
E+E E RE+ ++ + E+DEE+ E + +KL E E + +KKT E
Sbjct: 416 EREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREY 475
Query: 73 RNLHKLLYNRPGTVSSLKKNVGQF-SGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLD 131
+ R ++ K + +F + ++ +Y + + K+ R+ + + D
Sbjct: 476 EKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERD 535
Query: 132 LERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEI 191
+R E +++ L HP P + M ++A+R + P+I
Sbjct: 536 RKREKEELEEIRQRLLAEGHPDPDAE------------------LQRMEQEAERRRQPQI 577
Query: 192 LSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKRE--KPKQKATSKSKKSVKSANVK 249
+ S +E+E+K ++E +E E EEEP +K + +P A S S S +
Sbjct: 578 KQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNT 637
Query: 250 KADSSTTK---KNQNSSKKESESE-------------DSSDDEPLIKKLKKPPTD 288
D S ++NS ++ E +S +P K KK P D
Sbjct: 638 PGDESPCGIIIPHENSPDQQQPEEHRPKIGLSLKLGASNSPGQPNSVKRKKLPVD 692
Score = 44.7 bits (104), Expect = 1e-04
Identities = 35/163 (21%), Positives = 77/163 (47%), Gaps = 18/163 (11%)
Query: 161 KSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDE--DKESE 218
K+++ + ++E MA++AKR K E L D +D K + + D+E E
Sbjct: 471 KTREYEKEAEREEERRREMAKEAKRLK--EFLEDYDDDRDDPKYYRGSALQKRLRDREKE 528
Query: 219 EEPPKKTAKREKP-----KQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSS 273
E ++ KREK +Q+ ++ A +++ + ++ Q K+E ESE+
Sbjct: 529 MEADERDRKREKEELEEIRQRLLAEGHPD-PDAELQRMEQEAERRRQPQIKQEPESEEEE 587
Query: 274 DDEPLIKKLKKPPTDEE--------LKETIKKLLASANLEEVT 308
+++ ++ ++ P +EE LK T++ + ++ ++ +
Sbjct: 588 EEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSAS 630
Score = 37.0 bits (84), Expect = 0.025
Identities = 31/174 (17%), Positives = 75/174 (43%), Gaps = 11/174 (6%)
Query: 159 LPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSD---ESSSDEDEKKNKEESSDDEDK 215
+ K ++ + ++ER R+ +R + E + E D D + KE D + +
Sbjct: 305 IEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRE 364
Query: 216 ESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDD 275
+ ++++ R K + ++ KS+ + ++ + ++ + ++E E E +
Sbjct: 365 RDRDRDRERSSDRNKDRSRSREKSRDRERE---RERERERERERERERERERERERERER 421
Query: 276 EPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLTERK 329
E +K KK +E+ ++ ++ L E K+ + E +++ ERK
Sbjct: 422 EREREKDKKRDREEDEEDAYERRKLERKLRE---KEAAYQ--ERLKNWEIRERK 470
Score = 33.5 bits (75), Expect = 0.28
Identities = 30/156 (19%), Positives = 65/156 (41%), Gaps = 10/156 (6%)
Query: 128 EVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARK---AK 184
E LD E + +++K + L+ S P + KK+ + R+ A
Sbjct: 194 EALD-EETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAP 252
Query: 185 RTKCPEILSDESSSDEDEKKNKEESSD------DEDKESEEEPPKKTAKREKPKQKATSK 238
P I ++ ++ E E+ ++ S D K+ EEE KK +R++ +++ +
Sbjct: 253 LIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRER 312
Query: 239 SKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSD 274
++ + ++ + ++ + +KE E E D
Sbjct: 313 ERERERERERREREREREREREREKEKERERERERD 348
Score = 33.5 bits (75), Expect = 0.28
Identities = 17/40 (42%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Query: 16 QPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLC 55
QP ++EPE EE +E+E++ +E EEEE+ + QK C
Sbjct: 574 QPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPE-QKPC 612
Score = 30.8 bits (68), Expect = 1.8
Identities = 23/124 (18%), Positives = 54/124 (43%), Gaps = 7/124 (5%)
Query: 161 KSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEE 220
K + + S+ R+ +R + E + E E++ + E D+E +EE
Sbjct: 379 KDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEE 438
Query: 221 PPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIK 280
+ K E+ ++ + ++ +K+ +++ +K +KE+E E+ E + K
Sbjct: 439 DAYERRKLERKLREKEAAYQERLKNWEIRE------RKKTREYEKEAEREEERRRE-MAK 491
Query: 281 KLKK 284
+ K+
Sbjct: 492 EAKR 495
Score = 30.4 bits (67), Expect = 2.4
Identities = 21/101 (20%), Positives = 43/101 (42%), Gaps = 5/101 (4%)
Query: 195 ESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSK-KSVKSANVKKADS 253
E + EK+ +E + ++E E E ++ +RE+ +++ + K K + + D
Sbjct: 292 EEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDR 351
Query: 254 STTKKNQNSSKKE----SESEDSSDDEPLIKKLKKPPTDEE 290
TK+ +E + E SSD + ++ D E
Sbjct: 352 DRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRE 392
Score = 28.9 bits (63), Expect = 6.9
Identities = 14/41 (34%), Positives = 21/41 (51%)
Query: 8 AEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEK 48
AEG P E E R+ ++E E +EEEEE+++
Sbjct: 552 AEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQE 592
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 57.0 bits (136), Expect = 2e-08
Identities = 50/192 (26%), Positives = 82/192 (42%), Gaps = 21/192 (10%)
Query: 153 KPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDD 212
K K P+S T S +K RN S +KA S ++D+KK+ ++ +
Sbjct: 360 KKDTKKYPESTDTESGDAKDARNDSRNLKKA-------------SKNDDKKKDAKKITFS 406
Query: 213 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVK-------KADSSTTKKNQNSSKK 265
D ESE E + +K K+ + + +KKSVK+ K DS KK++ KK
Sbjct: 407 TDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKK 466
Query: 266 ESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDL 325
+S+ +D D + + +D ELK+ K ++ K K +D
Sbjct: 467 DSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDE 526
Query: 326 TERKDFIKTTVK 337
+ + F KT+ K
Sbjct: 527 SSKTGF-KTSTK 537
Score = 49.7 bits (117), Expect = 4e-06
Identities = 37/138 (26%), Positives = 62/138 (44%), Gaps = 8/138 (5%)
Query: 162 SKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEP 221
+KK K S E S A+K + + D+ D K ES+D E +S++E
Sbjct: 288 TKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDV---KKDTESTDAESGDSKDE- 343
Query: 222 PKKTAKREKPKQKATSKSKKSVK---SANVKKADSSTTKKNQNSSKKESESEDSSDDEPL 278
+K K++K K K K K + K S + + D+ + + + KK S+++D D
Sbjct: 344 -RKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKK 402
Query: 279 IKKLKKPPTDEELKETIK 296
I ++ E KE+ K
Sbjct: 403 ITFSTDSESELESKESQK 420
Score = 47.4 bits (111), Expect = 2e-05
Identities = 39/155 (25%), Positives = 68/155 (43%), Gaps = 23/155 (14%)
Query: 200 EDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSK---KSVKSANVKKADSSTT 256
+D KKN ++SSD E ++S++ KK +K+ K K K K K +S + + DS
Sbjct: 286 KDTKKNAKKSSDAESEDSKDA--KKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDE 343
Query: 257 KKNQNSSKK------------------ESESEDSSDDEPLIKKLKKPPTDEELKETIKKL 298
+K+ KK ++ES D+ D + LKK +++ K+ KK+
Sbjct: 344 RKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKI 403
Query: 299 LASANLEEVTMKQICKKVYENYPTYDLTERKDFIK 333
S + E + +K + T+ K +K
Sbjct: 404 TFSTDSESELESKESQKDEKKDKKDSKTDNKKSVK 438
Score = 44.7 bits (104), Expect = 1e-04
Identities = 66/250 (26%), Positives = 94/250 (37%), Gaps = 42/250 (16%)
Query: 90 KKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFL 149
KK G ++ P K V+ K K + + LKS E ++S +SE N
Sbjct: 132 KKKGGSYATNPESKQIVEEKTKRQ--NEADKTPLKSSHENEQSKKSKSSSETNPESQN-- 187
Query: 150 MHPKPSGKPLPKSKKTCSKGSKK--------ERNSSGMARKAKRTKCP--EILSDES--- 196
K K + K SK SKK + N +++K + P EI S+ S
Sbjct: 188 --SKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNV 245
Query: 197 --------SSDE-------------DEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKA 235
S DE + KN K+ ++ KK++ E K
Sbjct: 246 DFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKD 305
Query: 236 TSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETI 295
K K VK NVKK D K S ++ES DS D+ KK KK ++ K+
Sbjct: 306 AKKDSKKVKK-NVKKDDKKKDVKKDTES-TDAESGDSKDERKDTKKDKKKLKKDDKKKDT 363
Query: 296 KKLLASANLE 305
KK S + E
Sbjct: 364 KKYPESTDTE 373
Score = 44.7 bits (104), Expect = 1e-04
Identities = 40/152 (26%), Positives = 63/152 (41%), Gaps = 18/152 (11%)
Query: 153 KPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSD-----EDEKKNKE 207
K S + K K SKK + + K K K +D S D +D KK+K+
Sbjct: 293 KKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKK 352
Query: 208 ESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKN-------Q 260
+ D+ K+ ++ P+ T + A + S+ N+KKA + KK
Sbjct: 353 KLKKDDKKKDTKKYPESTDTESGDAKDARNDSR------NLKKASKNDDKKKDAKKITFS 406
Query: 261 NSSKKESESEDSSDDEPLIKKLKKPPTDEELK 292
S+ E ES++S DE KK K + +K
Sbjct: 407 TDSESELESKESQKDEKKDKKDSKTDNKKSVK 438
Score = 40.4 bits (93), Expect = 0.002
Identities = 35/139 (25%), Positives = 63/139 (45%), Gaps = 15/139 (10%)
Query: 161 KSKKTCSKGSKKERNSSGMARK-----AKRTKCPEILSDESSSDEDEKKNKEESSDDEDK 215
K KT +K S K S A +K+ K E + S +D+KK+ +++++ +
Sbjct: 427 KDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEM 486
Query: 216 ESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNS-----SKKESESE 270
ES+ E K++K K SKK +K K +S+ + +++S + + +
Sbjct: 487 ESDLE-----LKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGS 541
Query: 271 DSSDDEPLIKKLKKPPTDE 289
D+ +E L K K DE
Sbjct: 542 DTESEESLYKPGAKKKIDE 560
Score = 38.1 bits (87), Expect = 0.011
Identities = 34/136 (25%), Positives = 61/136 (44%), Gaps = 7/136 (5%)
Query: 181 RKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSK 240
+KA+ K + + +KK +++ E K+ EE K+ + +K K++ +++
Sbjct: 111 KKAEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENE 170
Query: 241 KSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTD-EELKETIKKLL 299
+S KS K+ S T ++QNS K S D+ K KK T+ K KK L
Sbjct: 171 QSKKS----KSSSETNPESQNS--KTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDL 224
Query: 300 ASANLEEVTMKQICKK 315
+ + +IC +
Sbjct: 225 KRSKTSNDPISEICSE 240
Score = 38.1 bits (87), Expect = 0.011
Identities = 57/260 (21%), Positives = 106/260 (40%), Gaps = 28/260 (10%)
Query: 22 EPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYN 81
+ E ++E ++ + + + +++++K +K E +K ++ RNL K N
Sbjct: 334 DAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKN 393
Query: 82 RPGTVSSLKKNVGQFSGFPFE-KGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSE 140
+ K S E K S + +KK++ K N KS+ D E + +SE
Sbjct: 394 DDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNK--KSVKN--DEESTDADSE 449
Query: 141 LVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILS------- 193
PK K K +K K SKK+ + A+ T+ L
Sbjct: 450 -----------PKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKH 498
Query: 194 --DESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKAT-SKSKKSVKSANVKK 250
++ S +D KK+ + ++ D E +E KT + K K + ++S++S+ KK
Sbjct: 499 SKEKKGSKKDIKKDARKDTESTDAEFDES--SKTGFKTSTKIKGSDTESEESLYKPGAKK 556
Query: 251 ADSSTTKKNQNSSKKESESE 270
+ + NS + ES+
Sbjct: 557 KIDESDGTSANSKMEGLESK 576
Score = 34.7 bits (78), Expect = 0.13
Identities = 50/213 (23%), Positives = 82/213 (38%), Gaps = 39/213 (18%)
Query: 156 GKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDE--SSSDEDEKKNKEESSDDE 213
G PL K K KG N ++TK SS E+E+ K +SS +
Sbjct: 124 GTPLKKDSK--KKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSET 181
Query: 214 DKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESE--SED 271
+ ES+ +K K+ + + K + + + K K+++ S+ SE SE+
Sbjct: 182 NPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSEN 241
Query: 272 S-----------SDDEPL------------------IKKLKKPPTDEELKETIKKLLASA 302
S SDDE + +K K T ++ K+ KK +
Sbjct: 242 SLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKY--TKKDTKKNAKKSSDAE 299
Query: 303 NLEEVTMKQICKKVYENYPTYDLTERKDFIKTT 335
+ + K+ KKV +N D ++KD K T
Sbjct: 300 SEDSKDAKKDSKKVKKNVKKDD--KKKDVKKDT 330
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 57.0 bits (136), Expect = 2e-08
Identities = 42/148 (28%), Positives = 71/148 (47%), Gaps = 13/148 (8%)
Query: 191 ILSDESSSDEDEKKNKEESSDDEDKESEEEPP--------KKTAKREKPKQKATSKSKKS 242
+LSD SS+++E ++ +D DK +EPP KT K+EKP++K +K
Sbjct: 109 LLSDIISSEDEED---DDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHK 165
Query: 243 VKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASA 302
K +K + + + K++ E ++ + + L K+ KK T E+ +E KK +
Sbjct: 166 EKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGG 225
Query: 303 NLEEVTMKQICKKVYENYPTYDLTERKD 330
E+V KQ KV E T + K+
Sbjct: 226 KQEKV--KQTAAKVKEVQKTPSKPKEKE 251
Score = 53.9 bits (128), Expect = 2e-07
Identities = 72/312 (23%), Positives = 115/312 (36%), Gaps = 77/312 (24%)
Query: 35 EEDEDDEEEEEEEKGK-GQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNV 93
E++EDD+ +E+ +KG+ + + IH K KT++ + + +
Sbjct: 117 EDEEDDDGDEDTDKGEIDEPPLRKKEIH----KDKTEKQEKPERKIQTK----------- 161
Query: 94 GQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPK 153
V +K+KE+ +K R E E+ + E +++ K
Sbjct: 162 ------------VTHKEKEKGKEKVR--------EKEKPEKKATHKEKIEK------KEK 195
Query: 154 PSGKPLPKSKKTCSKGSKKERNS-----SGMARKAKRT--KCPEILSDESSSDEDEKKNK 206
P K L K +K K E + G K K+T K E+ S E E K K
Sbjct: 196 PETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEK 255
Query: 207 EESSDDEDKESEE----------------------EPPKKTAKREKPKQKATS-KSKKSV 243
S E K+ PP T + +P + + + K+
Sbjct: 256 AAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGE 315
Query: 244 KSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASAN 303
K KK S T KK + KK+SE E + D E K+P E K+ K+ A A
Sbjct: 316 KKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEK-----KEPGKASETKQGTVKIAAQAA 370
Query: 304 LEEVTMKQICKK 315
++ K+ KK
Sbjct: 371 AKKDEKKEDSKK 382
Score = 48.5 bits (114), Expect = 8e-06
Identities = 34/144 (23%), Positives = 69/144 (47%), Gaps = 8/144 (5%)
Query: 182 KAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKK 241
K ++ + PE + ++++K KE+ + E E + +K K+EKP+ K +K +K
Sbjct: 147 KTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQK 206
Query: 242 SVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLAS 301
K+A + TKK K+E + ++ +K+++K P+ + KE +K S
Sbjct: 207 KAKTA---EKSEEKTKKEVKGGKQEKVKQTAAK----VKEVQKTPSKPKEKEDKEKAAVS 259
Query: 302 ANLEEVTMKQICKKVYENYPTYDL 325
+ E+ C+ + + + DL
Sbjct: 260 KH-EQKDQYAFCRYMIDIFVHGDL 282
Score = 47.8 bits (112), Expect = 1e-05
Identities = 70/316 (22%), Positives = 128/316 (40%), Gaps = 69/316 (21%)
Query: 13 TPTQPASEKEPEMPGPREESEEE-EDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDE 71
TP PA E E G ++++E++ E ++E+E+ K K +K I+ + KK+
Sbjct: 303 TPASPALE---EKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAID-----VEKKE--- 351
Query: 72 LRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLD 131
PG S K+ + + + + + +KKE+ K + A ++
Sbjct: 352 -----------PGKASETKQGTVKIAA---QAAAKKDEKKEDSKKTKKPAEVE------- 390
Query: 132 LERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTC--SKGSKKERN-SSGMARKAKRTKC 188
+P GK K +K +K KKE + S KAK +
Sbjct: 391 ---------------------QPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERA 429
Query: 189 PEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANV 248
E + S K +E+++ ++E +E KT+ K K+ K +K S
Sbjct: 430 KEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKE 489
Query: 249 KKADSSTTKKNQNSSKK------ESESEDSSDDEPLIKKLKKPPTDEEL---KETI---K 296
K+ ++ +K + K+ + + + EP IKK KP E++ K+ I +
Sbjct: 490 KEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPE 549
Query: 297 KLLASANLEEVTMKQI 312
K ++ EE +KQ+
Sbjct: 550 KTVSHGKPEEKVLKQV 565
Score = 43.9 bits (102), Expect = 2e-04
Identities = 62/304 (20%), Positives = 112/304 (36%), Gaps = 48/304 (15%)
Query: 14 PTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDELR 73
PT+ AS P P E+ E++ + + E +K + + + KK E
Sbjct: 295 PTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDI------------KKKSEKE 342
Query: 74 NLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLE 133
+ PG S K+ + + + + + +KKE+ K + A ++ +
Sbjct: 343 TAIDVEKKEPGKASETKQGTVKIAA---QAAAKKDEKKEDSKKTKKPAEVE--------Q 391
Query: 134 RSGVNSELVKRILNFLMHPK-----PSGKPLPK------------SKKTCSKGSKKERNS 176
G E ++ + PK PS K + S K G K+E+ +
Sbjct: 392 PKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTT 451
Query: 177 SGMA---RKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQ 233
+ RK K K IL D+ E+K + E + ++E K K KPK
Sbjct: 452 KTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKP 511
Query: 234 KATSKSKKSVKSANVKK-ADSSTTKK----NQNSSKKESESEDSSDDEPLIKKLKKPPTD 288
K+ +KK A + ++K Q+ K E +E ++K++K +
Sbjct: 512 PQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIE 571
Query: 289 EELK 292
+ K
Sbjct: 572 KTAK 575
Score = 41.2 bits (95), Expect = 0.001
Identities = 73/344 (21%), Positives = 136/344 (39%), Gaps = 58/344 (16%)
Query: 16 QPASEKEPEMPGPREESEE------EEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKT 69
+ A + E + PG E+++ + ++E++E+ K +K E+E+ K K
Sbjct: 342 ETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQ-----PKGKK 396
Query: 70 DELRNLHKLLYNRPG---TVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSI 126
E + H P +V S K+ + E G+V KK K+ + K++
Sbjct: 397 QEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTT--KTV 454
Query: 127 CEVLDLERSGVNSELVK----------RILNFLMHPKPSGKPLPKSKKTCSK-------- 168
+ + E+SG S ++K ++ L +P K K K +
Sbjct: 455 EQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQL 514
Query: 169 -GSKKERNSSGMARKAK-------RTKCPEILSDE---SSSDEDEKKNKEESSDDEDKES 217
G K+E+ + ++AK + +I+ E S +EK K+ + +K +
Sbjct: 515 QGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTA 574
Query: 218 EEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEP 277
+ +P KK RE + S+K+ K T++ ++ KK SE S ++
Sbjct: 575 KPKPTKKAEHRE--------REPPSIKTDKPKPTPKGTSEVTESGKKKTEISEKESKEKA 626
Query: 278 LIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYP 321
+K L+ EE T K+ L N+ + K E+ P
Sbjct: 627 DMKHLR-----EEKVSTRKESLQLHNVTKAEKPARVSKDVEDVP 665
Score = 33.1 bits (74), Expect = 0.37
Identities = 69/299 (23%), Positives = 123/299 (41%), Gaps = 51/299 (17%)
Query: 4 SAPAAEGEGTPTQPASEK------EPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEI 57
S P+ + T+ A E+ + +PG +EE + E +E +E+ GK + +
Sbjct: 415 SVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVE--QEIRKEKSGKTSSILKD 472
Query: 58 --------ERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYK 109
E++ L K+K E + K+ ++ G +K Q G EK Q K
Sbjct: 473 KEPIKGKEEKVPASL-KEKEPETKKDEKM--SKAG--KEVKPKPPQLQGKKEEKPEPQIK 527
Query: 110 KKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKK-TCSK 168
K+ + +I E + + + ++VK + H KP K L + K T K
Sbjct: 528 KEAK----------PAISEKVQIHKQ----DIVKPEKT-VSHGKPEEKVLKQVKAVTIEK 572
Query: 169 GSKKERNSSGMARKAK----RTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKK 224
+K + R+ + +T P+ +S + K K E S+ KES+E+ K
Sbjct: 573 TAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISE---KESKEKADMK 629
Query: 225 TAKREKPKQKATSKSKKSVKSANVKKAD--SSTTKKNQNSSKKESESEDSSDDEPLIKK 281
+ EK S K+S++ NV KA+ + +K ++ + E + D P +K
Sbjct: 630 HLREEK-----VSTRKESLQLHNVTKAEKPARVSKDVEDVPASKKAKEGTEDVSPTKQK 683
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 57.0 bits (136), Expect = 2e-08
Identities = 44/158 (27%), Positives = 70/158 (44%), Gaps = 21/158 (13%)
Query: 157 KPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKE 216
K L KS++ G++ +K K+ C S SSS D + +S D+E K+
Sbjct: 71 KELEKSREKLLSGNESSSKKRERKKKRKKKSCR---SSSSSSSSDSSSSSSDSEDEEKKQ 127
Query: 217 SEEEPPKKTAKREKPKQKAT----SKSKKSVKSANVKKADSSTTKKNQNSSKK------- 265
+ KK + K Q +T S+SK+SVK K ++ K ++ SKK
Sbjct: 128 GKRRKKKKN-RSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPD 186
Query: 266 ------ESESEDSSDDEPLIKKLKKPPTDEELKETIKK 297
ES SE +++ KK ++ E+ KE +KK
Sbjct: 187 DKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKK 224
Score = 55.5 bits (132), Expect = 7e-08
Identities = 45/163 (27%), Positives = 80/163 (49%), Gaps = 21/163 (12%)
Query: 145 ILNFLMHPKPSGKPLPKSKKTCSKGSK-----KERNSSGMARKAKRTKCPEILSDESSSD 199
I ++L P+P+ + + K + GSK +E+ + ++ ++++ + +ESSS
Sbjct: 30 IQDYLNRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSK 89
Query: 200 EDEKKNKEE-----------SSDDEDKESE-EEPPKKTAKREKPKQKATSKSKKSVKSAN 247
+ E+K K + SSD S+ E+ KK KR K K+ + KS +S S +
Sbjct: 90 KRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQS--STH 147
Query: 248 VKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEE 290
+++S + K + SK E+E E D L KK KK D++
Sbjct: 148 ESESESKESVKKKKKSKDETEKE--KDVRSLSKKRKKSYPDDK 188
Score = 42.4 bits (98), Expect = 6e-04
Identities = 62/246 (25%), Positives = 95/246 (38%), Gaps = 50/246 (20%)
Query: 22 EPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYN 81
E + G + +E EE ++ ++E EK + + L E S K E + K
Sbjct: 49 ENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNE------SSSKKRERKKKRKKKSC 102
Query: 82 RPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSEL 141
R + SS + S E+ KK+ + KK +N KS + S SE
Sbjct: 103 RSSSSSSSSDSSSSSSDSEDEE-----KKQGKRRKKKKNRSYKSS------QSSTHESE- 150
Query: 142 VKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDED 201
K K KK ++KE++ +++K K+ S D
Sbjct: 151 ------------SESKESVKKKKKSKDETEKEKDVRSLSKKRKK------------SYPD 186
Query: 202 EKKNKEESSDDEDKESEEEPPKKTA--KREKPKQKATSKSKKSVKSANVKKADSSTTKKN 259
+K ESS + D E + + KK +RE+ K+K K KK K + KK KK
Sbjct: 187 DKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKK------KKK 240
Query: 260 QNSSKK 265
SS K
Sbjct: 241 SGSSHK 246
Score = 41.2 bits (95), Expect = 0.001
Identities = 44/179 (24%), Positives = 67/179 (37%), Gaps = 23/179 (12%)
Query: 104 GSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSK 163
G+ KK E KK + +S + S +S+ K GK K K
Sbjct: 83 GNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDE-------EKKQGKRRKKKK 135
Query: 164 KTCSKGSKK-----ERNSSGMARKAKRTKCPEILSDESSSDED----EKKNKEESSDDED 214
K S+ E S +K K++K DE+ ++D KK K+ DD+
Sbjct: 136 NRSYKSSQSSTHESESESKESVKKKKKSK------DETEKEKDVRSLSKKRKKSYPDDKP 189
Query: 215 KESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSS 273
SE + + K+K + ++ K VKK KK+ KK+S S S
Sbjct: 190 LSSESSSESDYEEDVQAKKKRRCEEREQAKE-KVKKKKKKQHKKHSKKKKKKSGSSHKS 247
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 56.6 bits (135), Expect = 3e-08
Identities = 71/337 (21%), Positives = 153/337 (45%), Gaps = 47/337 (13%)
Query: 9 EGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGK-GQKLCEIERIHFFLSKK 67
E E T T S ++ + E +E++++++EEEE+ ++G G+ E+ + ++
Sbjct: 161 EIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEV------MVEE 214
Query: 68 KTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSIC 127
KT E + ++ + G +SS + + E+GS + E+M ++ +
Sbjct: 215 KTTESQEETVVMSLKNGQISSEEPKQEE----EREQGSDEISHHEKMEEEDK-------- 262
Query: 128 EVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTK 187
E + ER+ + +E +RI + KK + ++ E A++ +R +
Sbjct: 263 ERAEAERARLEAEERERI------------KAEQDKKIADERARIEAEEKAAAQERERRE 310
Query: 188 CPE---ILSDESSSDEDEKKNKEESS-DDEDKESEEEPPKKTA---KREKPKQKATSKSK 240
E + +E + E+ ++ KEE E+++ +E K+ A +R K ++K ++ +
Sbjct: 311 AEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEER 370
Query: 241 KSVKSANVKKADSSTTKKN-QNSSKKESESEDSSDDEPLIKKL------KKPPTDEELKE 293
+ ++ +KA K+N Q KK + E E + +K+ +K +++L+
Sbjct: 371 QRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQT 430
Query: 294 TIKKLLASANLEEVTMKQICKKVYENYPTYDLTERKD 330
+ K +V K+ +K+ E+ PT+ E KD
Sbjct: 431 AVLKKQGEEKGTKVQAKR--EKLQEDKPTFKKEEIKD 465
Score = 40.4 bits (93), Expect = 0.002
Identities = 54/295 (18%), Positives = 123/295 (41%), Gaps = 45/295 (15%)
Query: 25 MPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPG 84
+P R +++ E+E E+EE+ E Q+ EIE + ++ R+ +
Sbjct: 132 LPSRRMQNDTAENETTEKEEKSESR--QERYEIEETETVTKSYQKNDWRDAEE------- 182
Query: 85 TVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKR 144
K + K++EE K R ++ ++ EV+ E++ + E +
Sbjct: 183 -----------------NKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQE--ET 223
Query: 145 ILNFLMHPKPSGKPLPKSKKTCSKGSK------------KERNSSGMAR-KAKRTKCPEI 191
++ L + + S + PK ++ +GS KER + AR +A+ + +
Sbjct: 224 VVMSLKNGQISSEE-PKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKA 282
Query: 192 LSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKA 251
D+ +DE + EE + +++E E ++ + E +K ++ ++ +K + A
Sbjct: 283 EQDKKIADERARIEAEEKAAAQERERREAEERERMREE---EKRAAEERQRIKEEEKRAA 339
Query: 252 DSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEE 306
+ K + E +++ ++ ++ +EE K +++ + LEE
Sbjct: 340 EERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEE 394
Score = 36.6 bits (83), Expect = 0.033
Identities = 61/305 (20%), Positives = 126/305 (41%), Gaps = 42/305 (13%)
Query: 18 ASEKEPEMPGPREESEEEEDEDDEE----EEEEEKGKGQKLCEIERIHFFLSKKKTDELR 73
A EK R E+EE E +EE EE + + +K ER +K+ E R
Sbjct: 297 AEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEER 356
Query: 74 NLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLE 133
K R + + EK V+ +K+ + L++ ++AM +
Sbjct: 357 QRIKEEEKRAAEERQRARAEEE------EKAKVEEQKRNKQLEEKKHAM----------Q 400
Query: 134 RSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILS 193
+ + E V++ K GK + + K +++++ + + +K K ++ +
Sbjct: 401 ETKIKGEKVEQ--------KIEGKWVNEKK------AQEDKLQTAVLKKQGEEKGTKVQA 446
Query: 194 DESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKK---SVKSANVKK 250
ED+ K+E DE + ++E PK+ K ++K ++ K + +K
Sbjct: 447 KREKLQEDKPTFKKEEIKDEKIKKDKE-PKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKH 505
Query: 251 ADSSTTKKNQNSS--KKESESEDSSDDEPLIKKL--KKPPTDEELKETIKKLLASANLEE 306
+++ ++ +S KE+E + +++L ++ T+ E E +K+ A LE
Sbjct: 506 TENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALEL 565
Query: 307 VTMKQ 311
+K+
Sbjct: 566 EELKK 570
Score = 36.2 bits (82), Expect = 0.043
Identities = 65/298 (21%), Positives = 112/298 (37%), Gaps = 22/298 (7%)
Query: 16 QPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDELRNL 75
Q E+E R+ +EEE EE + ++ + + E +R +K E +
Sbjct: 329 QRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKR 388
Query: 76 HKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERS 135
+K L + + K G+ E V KK +E K + A+LK E
Sbjct: 389 NKQLEEKKHAMQETKIK-GEKVEQKIEGKWVNEKKAQE--DKLQTAVLKK-----QGEEK 440
Query: 136 GVNSELVKRILNFLMHPKPSGKPLP-KSKKTCSKGSKKERNSSGMARKAKRTKCP----E 190
G + + L KP+ K K +K KE S M RK T+ E
Sbjct: 441 GTKVQAKREKLQ---EDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGE 497
Query: 191 ILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKR-EKPKQKATSKSKKSVKSANVK 249
++ + E+ + + KE+E P + KR E+ +++ + + K
Sbjct: 498 FMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQK 557
Query: 250 KADSSTT-----KKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASA 302
+ +++ KK + K E E E +KL++ LKE I++ A A
Sbjct: 558 QQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEA 615
Score = 35.8 bits (81), Expect = 0.057
Identities = 57/269 (21%), Positives = 105/269 (39%), Gaps = 38/269 (14%)
Query: 20 EKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDELRNLHKLL 79
EK ++ RE+ +E++ +EE ++EK K K + E F KK E+++
Sbjct: 439 EKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKS----- 493
Query: 80 YNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNS 139
N LK FS P + SV K+ E + L E L R S
Sbjct: 494 QNGEFMTHKLKHTENTFSR-PGGRASVDTKEAEGAPQVEAGKRL----EELRRRRGETES 548
Query: 140 ELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSD 199
E +++ K ++E K KR + ++L +E
Sbjct: 549 EEFEKL----------------------KQKQQEAALELEELKKKREERRKVLEEEEQRR 586
Query: 200 EDEKKNKEESSDDEDKESEEEPPKKTA----KREKPKQKATSKSKKSVKSANVKKADSST 255
+ E+ +++ ++E + +EE ++ A KR+K + S KK K K +
Sbjct: 587 KQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKI 646
Query: 256 TKKNQ--NSSKKESESEDSSDDEPLIKKL 282
++ + N S ++S S+ ++ K+
Sbjct: 647 EERAEFLNKSVQKSSGVKSTHQAAIVSKI 675
Score = 30.0 bits (66), Expect = 3.1
Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 11/73 (15%)
Query: 3 ASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHF 62
AS E EG P A ++ E+ R E+E EE E +++++E E+E +
Sbjct: 517 ASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQE------AALELEEL-- 568
Query: 63 FLSKKKTDELRNL 75
KKK +E R +
Sbjct: 569 ---KKKREERRKV 578
Score = 28.9 bits (63), Expect = 6.9
Identities = 30/130 (23%), Positives = 56/130 (43%), Gaps = 15/130 (11%)
Query: 171 KKERNSSGMARKAKRTKCPEILSDESSSDEDEKK---NKEESSDDEDKESEEEPPKKTAK 227
K+E S G T E+ + S DE+ K N + DDE E + A+
Sbjct: 53 KQEEESLGQV-----TDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLE-----RLAR 102
Query: 228 REKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPT 287
RE+ +QK ++ + K + D+S + ++ +E+E + +E + ++
Sbjct: 103 REERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEI 162
Query: 288 DEELKETIKK 297
+E ET+ K
Sbjct: 163 EE--TETVTK 170
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 56.2 bits (134), Expect = 4e-08
Identities = 50/196 (25%), Positives = 88/196 (44%), Gaps = 14/196 (7%)
Query: 111 KEEMLKKFRNAMLKSICEVL--DLERSGVNSELV----KRILNFLMHPKPSGKPLPKSKK 164
KEE + + + + + EV+ D E G+ E V KR K KP K
Sbjct: 2156 KEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSS 2215
Query: 165 TCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESS---DDEDKESEEEP 221
+ +E S M + E LS E + +E++ +EE ++E+++ EEE
Sbjct: 2216 QVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEG 2275
Query: 222 PKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKK 281
+K ++E+ ++K K KK K V++ + +K + S++E+ES SD+E +
Sbjct: 2276 EEKQVEKEEEEKK---KKKKEKKKEEVQEKEEVFEEKEEIMSEEETES--LSDEEEEEES 2330
Query: 282 LKKPPTDEELKETIKK 297
+ KE +KK
Sbjct: 2331 CSLEEEVDREKEILKK 2346
Score = 40.0 bits (92), Expect = 0.003
Identities = 61/296 (20%), Positives = 116/296 (39%), Gaps = 45/296 (15%)
Query: 16 QPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDELRNL 75
Q + +E + G +E ++ EEE+ +K K + + +E L K K
Sbjct: 1320 QEGAIREDMIQGVTQEVIRHKEVMPREEEQAQK-KARDMLGLEETQVILKKGK------- 1371
Query: 76 HKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKK-----------KEEMLKKFRNAMLK 124
K+++ PG V+ K+ + F+K Q +K K EM K+ R+ M +
Sbjct: 1372 -KVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERD-MSE 1429
Query: 125 SICEVLDLERSGVNSE----LVKRILNFLMHPKP--SGKPLPKSKKTCSKGSKKERNSSG 178
+ E+ LE V E +++R ++ K K + + K K+E
Sbjct: 1430 EVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRL 1489
Query: 179 MARKAKRTKCPEILSDESSSDEDEKKNKEES------------------SDDEDKESEEE 220
+ + K + E LS E +++KK K E D+E+ EEE
Sbjct: 1490 LQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEE 1549
Query: 221 PPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDE 276
++ ++E+ + ++ K A + + + KK +K ++ E+ E
Sbjct: 1550 VSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQE 1605
Score = 36.6 bits (83), Expect = 0.033
Identities = 56/252 (22%), Positives = 99/252 (39%), Gaps = 28/252 (11%)
Query: 103 KGSVQYKKKEEMLKKFR---NAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPL 159
K S + KK E L K N +LK++ ++ ER E+ + + K +
Sbjct: 2054 KASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSI 2113
Query: 160 PKSKKTCS------KGSKKERNSSGMARKAKR--TKCPEILSDESSSDEDEKKNKEESS- 210
+SK K S+ ++ +ARK ++ K +++ E E+E K + S
Sbjct: 2114 EQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSE 2173
Query: 211 ----DDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE 266
D+E+ EEE KR K+K K+ D K + + E
Sbjct: 2174 VILDDEEEGGIEEEEVIPFLKRRWRKRK------------EAKRGDKPKEKFSSQVDEVE 2221
Query: 267 SESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLT 326
SE S + E L+ +L+K + +E ++ EEV ++ +K E +
Sbjct: 2222 SEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVE 2281
Query: 327 ERKDFIKTTVKE 338
+ ++ K KE
Sbjct: 2282 KEEEEKKKKKKE 2293
Score = 35.4 bits (80), Expect = 0.074
Identities = 54/236 (22%), Positives = 101/236 (42%), Gaps = 26/236 (11%)
Query: 110 KKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKS--KKTCS 167
+ +E++ + K ++L LE + V + K+++ GK + K KKT
Sbjct: 1338 RHKEVMPREEEQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQ 1397
Query: 168 KGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAK 227
K K+ R + RK + K + + + D + EE + E+K ++E +
Sbjct: 1398 KSPKQGRKAVQKERKVGKIK-----REMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIE 1452
Query: 228 REKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPT 287
R P + K+ K + T+K+ + K+E E ++E L + +K
Sbjct: 1453 RT-PSWQDWKKAWDEWKQVH------GETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSP 1505
Query: 288 DEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLTER--KDFIKTTVKELIS 341
+EE+ + KKL EE K+V+EN + E+ KD + T++E +S
Sbjct: 1506 EEEMLQEDKKL----KWEE------WKQVWENMLSSKSKEQQYKDEEEVTLEEEVS 1551
Score = 35.0 bits (79), Expect = 0.097
Identities = 42/177 (23%), Positives = 77/177 (43%), Gaps = 23/177 (12%)
Query: 18 ASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKL-CEIERIHFFLSKKKTDELRNLH 76
+SE+E E E EEE E++EE +EEE+G+ +++ E E +KK +E++
Sbjct: 2244 SSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKE 2303
Query: 77 KLLYNRPGTVS-----SLKKNVGQFSGFPFE-----KGSVQYKKKEEMLKKFRNAMLKSI 126
++ + +S SL + E + + K+K+ L++ R L+
Sbjct: 2304 EVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGR 2363
Query: 127 CEVLDLERS-----------GVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKK 172
VL + R GV +K++++ + K P+P +K S KK
Sbjct: 2364 ERVLSILRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEK-TPVPVPEKQISWEDKK 2419
Score = 32.7 bits (73), Expect = 0.48
Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 2/51 (3%)
Query: 20 EKEPEMPGPREESEEEEDEDDEEE--EEEEKGKGQKLCEIERIHFFLSKKK 68
EK+ + EE EEE+E +EEE EEEE+ K ++ E +++ +KK
Sbjct: 2238 EKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKK 2288
Score = 31.6 bits (70), Expect = 1.1
Identities = 32/136 (23%), Positives = 57/136 (41%), Gaps = 11/136 (8%)
Query: 153 KPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDD 212
K S K L KKT + SK+ G+ T+ I +E+S +
Sbjct: 1091 KHSQKWLRGLKKTKERDSKQMSTEPGLLEDESGTEAAPIEMEEASVYSQWSSSTSVIKLS 1150
Query: 213 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESE--SE 270
+D +S+E+ K T K + ++ KKA + KK KE++ +E
Sbjct: 1151 KDVDSQEKDISKD------HIALTLKRLQKIRDKRDKKATAQKLKKKHKKKGKEAKVINE 1204
Query: 271 DSSD---DEPLIKKLK 283
+++ ++P+ KK+K
Sbjct: 1205 ETTPPVMEQPVTKKVK 1220
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 55.5 bits (132), Expect = 7e-08
Identities = 68/294 (23%), Positives = 116/294 (39%), Gaps = 38/294 (12%)
Query: 1 MSASAPAA---EGEGTPTQPASEKEPEMPGPREESEEE-----EDEDDEEEEEEEKGKGQ 52
+ A+AP EGE + E+E E G + + EE E ++EE E+E+G+ +
Sbjct: 513 VKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETE 572
Query: 53 KLCEIERIHFFLSKK---KTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYK 109
E E KK K++E+ +L V+ K + + P K V+ K
Sbjct: 573 AEAEGEEAEAKEEKKVEEKSEEVATKEEL-------VADAKVEKPEKAKSPVPKSPVEEK 625
Query: 110 KKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKG 169
K + K KS +E G + P P K K SK
Sbjct: 626 GKSPVPKSPVEEKGKSPVPKSPVEEKGKS-------------PVPKSPVEEKGKSPVSKS 672
Query: 170 SKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKRE 229
+E+ S + + + + E+E+K +E+ +E E +EE PK +++
Sbjct: 673 PVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKK 732
Query: 230 KP----KQKATSK---SKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDE 276
K K++A ++ KSVK K+ Q K+++ E S++E
Sbjct: 733 KAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEE 786
Score = 55.1 bits (131), Expect = 9e-08
Identities = 63/284 (22%), Positives = 112/284 (39%), Gaps = 13/284 (4%)
Query: 6 PAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLS 65
P AE E + + K EE E+EE+E EEEEEE++G E S
Sbjct: 499 PEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGS 558
Query: 66 KKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEML---KKFRNAM 122
+K + + + G + K+ E+ S + KEE++ K +
Sbjct: 559 SEKEEGEQEEGETEAEAEGEEAEAKEEK------KVEEKSEEVATKEELVADAKVEKPEK 612
Query: 123 LKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARK 182
KS +E G + + P P K K K +E+ S +++
Sbjct: 613 AKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKS 672
Query: 183 --AKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSK 240
++ K P S + + K E ++E+KE +E P ++ ++++ K K + K
Sbjct: 673 PVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKK 732
Query: 241 KSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKK 284
K+ + VK+ + S K E E + +PL ++ +K
Sbjct: 733 KA--ESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEK 774
Score = 45.1 bits (105), Expect = 9e-05
Identities = 43/180 (23%), Positives = 77/180 (42%), Gaps = 11/180 (6%)
Query: 161 KSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKE---- 216
KS + GS+KE +S + + + E + ++EKK +E+S + KE
Sbjct: 544 KSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVA 603
Query: 217 -SEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDD 275
++ E P+K AK PK K K V + V++ S K+ K +S S +
Sbjct: 604 DAKVEKPEK-AKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE 662
Query: 276 EPLIKKLKKPPTDEELKETIKK-----LLASANLEEVTMKQICKKVYENYPTYDLTERKD 330
E + K P +E+ K + K + A + + K+ +K + P + E+K+
Sbjct: 663 EKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKE 722
Score = 43.9 bits (102), Expect = 2e-04
Identities = 31/131 (23%), Positives = 67/131 (51%), Gaps = 6/131 (4%)
Query: 179 MARKAKRTKCPEILSDESSSDEDE---KKNKEESSDDEDKESEEEPPKKTAKREKPKQKA 235
++ K ++ + E +E ++E+E KK+ +++ E KE E E ++ + E+ ++
Sbjct: 482 VSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDE 541
Query: 236 TSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETI 295
+KS ++ + + K+ S + Q + E+E+E +E K+ KK E T
Sbjct: 542 GAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEG---EEAEAKEEKKVEEKSEEVATK 598
Query: 296 KKLLASANLEE 306
++L+A A +E+
Sbjct: 599 EELVADAKVEK 609
Score = 43.5 bits (101), Expect = 3e-04
Identities = 34/162 (20%), Positives = 67/162 (41%), Gaps = 4/162 (2%)
Query: 161 KSKKTCSKGSKKERNSSGMARKAKRTKC--PEILSDESSSDEDEKKNKEESSDDEDKESE 218
K + K + E +A K K PE+ +E +E+E + +EE D+ K +
Sbjct: 488 KKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQ 547
Query: 219 EEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPL 278
E + K++ + ++ A ++A++ KK + S++ + E+ D +
Sbjct: 548 AEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKV 607
Query: 279 IK--KLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYE 318
K K K P ++E K + + +EE + K E
Sbjct: 608 EKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE 649
Score = 36.2 bits (82), Expect = 0.043
Identities = 52/269 (19%), Positives = 102/269 (37%), Gaps = 22/269 (8%)
Query: 29 REESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRP----- 83
R + E D++ + EE K + KL E + + +E+ + L ++
Sbjct: 274 RSQLESHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELES 333
Query: 84 --GTVSSLKKNVGQFS-----GFPFEKGSVQYKKKE------EMLKKFRNAM-LKSICEV 129
GT SL++ + + ++Q + E EM + R L ++
Sbjct: 334 VRGTKESLERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQDLLNVKMA 393
Query: 130 LDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCP 189
LD+E + L F PL + + SK ++ + + K
Sbjct: 394 LDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFV 453
Query: 190 EILSDESSSDEDEKKNKEES--SDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSAN 247
E + +E+ EDEK EE+ + E+ + KK A EK ++ + + + K +
Sbjct: 454 EEIIEETKV-EDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSP 512
Query: 248 VKKADSSTTKKNQNSSKKESESEDSSDDE 276
VK ++ ++E + E+ +DE
Sbjct: 513 VKATAPEVKEEEGEKEEEEGQEEEEEEDE 541
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 55.5 bits (132), Expect = 7e-08
Identities = 68/294 (23%), Positives = 116/294 (39%), Gaps = 38/294 (12%)
Query: 1 MSASAPAA---EGEGTPTQPASEKEPEMPGPREESEEE-----EDEDDEEEEEEEKGKGQ 52
+ A+AP EGE + E+E E G + + EE E ++EE E+E+G+ +
Sbjct: 137 VKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETE 196
Query: 53 KLCEIERIHFFLSKK---KTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYK 109
E E KK K++E+ +L V+ K + + P K V+ K
Sbjct: 197 AEAEGEEAEAKEEKKVEEKSEEVATKEEL-------VADAKVEKPEKAKSPVPKSPVEEK 249
Query: 110 KKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKG 169
K + K KS +E G + P P K K SK
Sbjct: 250 GKSPVPKSPVEEKGKSPVPKSPVEEKGKS-------------PVPKSPVEEKGKSPVSKS 296
Query: 170 SKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKRE 229
+E+ S + + + + E+E+K +E+ +E E +EE PK +++
Sbjct: 297 PVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKK 356
Query: 230 KP----KQKATSK---SKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDE 276
K K++A ++ KSVK K+ Q K+++ E S++E
Sbjct: 357 KAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEE 410
Score = 55.1 bits (131), Expect = 9e-08
Identities = 63/284 (22%), Positives = 112/284 (39%), Gaps = 13/284 (4%)
Query: 6 PAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLS 65
P AE E + + K EE E+EE+E EEEEEE++G E S
Sbjct: 123 PEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGS 182
Query: 66 KKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEML---KKFRNAM 122
+K + + + G + K+ E+ S + KEE++ K +
Sbjct: 183 SEKEEGEQEEGETEAEAEGEEAEAKEEK------KVEEKSEEVATKEELVADAKVEKPEK 236
Query: 123 LKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARK 182
KS +E G + + P P K K K +E+ S +++
Sbjct: 237 AKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKS 296
Query: 183 --AKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSK 240
++ K P S + + K E ++E+KE +E P ++ ++++ K K + K
Sbjct: 297 PVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKK 356
Query: 241 KSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKK 284
K+ + VK+ + S K E E + +PL ++ +K
Sbjct: 357 KA--ESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEK 398
Score = 45.1 bits (105), Expect = 9e-05
Identities = 43/180 (23%), Positives = 77/180 (42%), Gaps = 11/180 (6%)
Query: 161 KSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKE---- 216
KS + GS+KE +S + + + E + ++EKK +E+S + KE
Sbjct: 168 KSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVA 227
Query: 217 -SEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDD 275
++ E P+K AK PK K K V + V++ S K+ K +S S +
Sbjct: 228 DAKVEKPEK-AKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE 286
Query: 276 EPLIKKLKKPPTDEELKETIKK-----LLASANLEEVTMKQICKKVYENYPTYDLTERKD 330
E + K P +E+ K + K + A + + K+ +K + P + E+K+
Sbjct: 287 EKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKE 346
Score = 43.9 bits (102), Expect = 2e-04
Identities = 31/131 (23%), Positives = 67/131 (51%), Gaps = 6/131 (4%)
Query: 179 MARKAKRTKCPEILSDESSSDEDE---KKNKEESSDDEDKESEEEPPKKTAKREKPKQKA 235
++ K ++ + E +E ++E+E KK+ +++ E KE E E ++ + E+ ++
Sbjct: 106 VSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDE 165
Query: 236 TSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETI 295
+KS ++ + + K+ S + Q + E+E+E +E K+ KK E T
Sbjct: 166 GAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEG---EEAEAKEEKKVEEKSEEVATK 222
Query: 296 KKLLASANLEE 306
++L+A A +E+
Sbjct: 223 EELVADAKVEK 233
Score = 43.5 bits (101), Expect = 3e-04
Identities = 34/162 (20%), Positives = 67/162 (41%), Gaps = 4/162 (2%)
Query: 161 KSKKTCSKGSKKERNSSGMARKAKRTKC--PEILSDESSSDEDEKKNKEESSDDEDKESE 218
K + K + E +A K K PE+ +E +E+E + +EE D+ K +
Sbjct: 112 KKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQ 171
Query: 219 EEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPL 278
E + K++ + ++ A ++A++ KK + S++ + E+ D +
Sbjct: 172 AEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKV 231
Query: 279 IK--KLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYE 318
K K K P ++E K + + +EE + K E
Sbjct: 232 EKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE 273
Score = 34.3 bits (77), Expect = 0.16
Identities = 20/84 (23%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Query: 195 ESSSDEDEKKNKEES--SDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKAD 252
E + EDEK EE+ + E+ + KK A EK ++ + + + K + VK
Sbjct: 82 EETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATA 141
Query: 253 SSTTKKNQNSSKKESESEDSSDDE 276
++ ++E + E+ +DE
Sbjct: 142 PEVKEEEGEKEEEEGQEEEEEEDE 165
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 55.5 bits (132), Expect = 7e-08
Identities = 54/193 (27%), Positives = 86/193 (44%), Gaps = 12/193 (6%)
Query: 153 KPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEE---S 209
KP+ KPLP K+ K SK+E + K P++ S E + +K K E S
Sbjct: 546 KPAAKPLPS--KSVRKESKEETPEVTKVNHVE--KPPKVESKEKVMVKKDKPIKTETKPS 601
Query: 210 SDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESES 269
+++ S+EEP K E +++AT K+ K VKK + + +K +
Sbjct: 602 VTEKEVPSKEEP--SPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKE 659
Query: 270 EDSSDDEPLIKKLKKPPTDE---ELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLT 326
+D+ IKK +KP +E E+K+ IKK +EV + K+V + +
Sbjct: 660 VAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKK 719
Query: 327 ERKDFIKTTVKEL 339
E K K KE+
Sbjct: 720 EVKKEEKEPKKEI 732
Score = 50.1 bits (118), Expect = 3e-06
Identities = 47/185 (25%), Positives = 80/185 (43%), Gaps = 11/185 (5%)
Query: 133 ERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEIL 192
E S V +E+ ++ + K + K K + K+E+ K K P
Sbjct: 612 EPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKK 671
Query: 193 SDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKAD 252
++ +E +K+ K+E +E KE PKK K+E P ++ + KK K VKK +
Sbjct: 672 EEKPKKEEVKKEVKKEIKKEEKKE-----PKKEVKKETPPKEVKKEVKKEEKK-EVKKEE 725
Query: 253 SSTTKKNQNSSK--KESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMK 310
K+ + K K+S + S +P K K P +E +K K +A+ +E
Sbjct: 726 KEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVK---KDSVAAGKPKEKGKI 782
Query: 311 QICKK 315
++ KK
Sbjct: 783 KVIKK 787
Score = 47.8 bits (112), Expect = 1e-05
Identities = 39/148 (26%), Positives = 70/148 (47%), Gaps = 8/148 (5%)
Query: 152 PKPSGKPLP-KSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSD--EDEKKNKEE 208
P + K +P K + + K E+ ++ + KA + K + + D E+++K K+E
Sbjct: 600 PSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKE 659
Query: 209 SSDDEDKE--SEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE 266
+ EDK +EE PKK +++ K++ + KK K K+ KK KKE
Sbjct: 660 VAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKK---EVKKE 716
Query: 267 SESEDSSDDEPLIKKLKKPPTDEELKET 294
+ E +++ K++KK P D + T
Sbjct: 717 EKKEVKKEEKEPKKEIKKLPKDAKKSST 744
Score = 42.4 bits (98), Expect = 6e-04
Identities = 49/232 (21%), Positives = 98/232 (42%), Gaps = 17/232 (7%)
Query: 65 SKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLK 124
SK++T E+ ++ + +P V S K+ V P + + ++E+ K + +K
Sbjct: 561 SKEETPEVTKVNHV--EKPPKVES-KEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVK 617
Query: 125 SICEVLDLERSGVNSELVK-RILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKA 183
+ EV + + + V + K + + KP K K K K+++ K
Sbjct: 618 A--EVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKP 675
Query: 184 KRTKCPEILSDESSSDEDEKKNKEESSD----DEDKESEEEPPKKTAKREKPKQKATSKS 239
K+ + + + E +E ++ KE + + KE ++E K+ K EK +K K
Sbjct: 676 KKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKL 735
Query: 240 KKSVKSANVKKADSS-------TTKKNQNSSKKESESEDSSDDEPLIKKLKK 284
K K ++ +++ K + S KK+S + ++ IK +KK
Sbjct: 736 PKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKK 787
Score = 35.8 bits (81), Expect = 0.057
Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 189 PEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANV 248
PE L+ E + + KK+ +E K ++P KT K P +K+ KSK S
Sbjct: 2222 PEALAIEQNLGKALKKDLKE------KTKTKKPGTKT-KSSSPVKKSDGKSKPLAASPKP 2274
Query: 249 KKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASAN 303
S+ K ++ +S K+ ES + + ++K +E+ KET ASA+
Sbjct: 2275 AGLKESSDKVSRVASPKKKESVEKAAKPTTTPEVKAARGEEKDKETKNAANASAS 2329
Score = 34.7 bits (78), Expect = 0.13
Identities = 31/136 (22%), Positives = 55/136 (40%), Gaps = 6/136 (4%)
Query: 129 VLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKC 188
++D E + L K + L + KP K+K S + S G ++ +
Sbjct: 2219 MVDPEALAIEQNLGKALKKDLKEKTKTKKPGTKTKS-----SSPVKKSDGKSKPLAASPK 2273
Query: 189 PEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAK-REKPKQKATSKSKKSVKSAN 247
P L + S K++ S ++ + P K A+ EK K+ + + + KSA
Sbjct: 2274 PAGLKESSDKVSRVASPKKKESVEKAAKPTTTPEVKAARGEEKDKETKNAANASASKSAK 2333
Query: 248 VKKADSSTTKKNQNSS 263
A TTK ++S+
Sbjct: 2334 TATAGPGTTKTTKSSA 2349
Score = 33.5 bits (75), Expect = 0.28
Identities = 72/319 (22%), Positives = 124/319 (38%), Gaps = 67/319 (21%)
Query: 1 MSASAPAAEGEGTPTQPASEKEPE---MPGPREESEEEEDEDDEEEEEEEKGKGQ----- 52
M+A+ AA G PA E E E M P + +++ E+ EE + + K Q
Sbjct: 809 MAAAGIAAIG------PAKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQLELIE 862
Query: 53 ---KLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYK 109
KL E E + ++ +K+ R + K P + + G+ P E V+ K
Sbjct: 863 DEEKLKETEPVEAYVIQKE----REVTKGPAESPDEGITTTEGEGECEQTPEELEPVE-K 917
Query: 110 KKEEMLKKFRN--AMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCS 167
+ + ++KF + A + E D E E + P+ G+ + C
Sbjct: 918 QGVDDIEKFEDEGAGFEESSETGDYEEKAETEEAEE--------PEEDGE-----EHVCV 964
Query: 168 KGSKKERNSSGMARKAK-----RTKCPEILSDESSSDED--------EKKNKEESSDDED 214
SK + KA+ R K + S + ++ED E + EE +D+ED
Sbjct: 965 SASKHSPTEDEESAKAEADAYIREKRESVASGDDRAEEDMDEAIEKGEAEQSEEEADEED 1024
Query: 215 K-----ESEEEPPKKTAKR------EKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSS 263
K E E EP K A+ +K + ++ + + K+ + + + SS
Sbjct: 1025 KAEDAREEEYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFLTTPTKQLGAQSPGREPASS 1084
Query: 264 KKE------SESEDSSDDE 276
+ SESE ++ DE
Sbjct: 1085 IHDETLPGGSESEATASDE 1103
Score = 33.5 bits (75), Expect = 0.28
Identities = 32/143 (22%), Positives = 57/143 (39%), Gaps = 14/143 (9%)
Query: 194 DESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADS 253
D+ EDE EESS+ D E + E T + E+P++ S + + +
Sbjct: 921 DDIEKFEDEGAGFEESSETGDYEEKAE----TEEAEEPEEDGEEHVCVSASKHSPTEDEE 976
Query: 254 STTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQIC 313
S + +++ ES S DD +E++ E I+K A + EE +
Sbjct: 977 SAKAEADAYIREKRESVASGDDR----------AEEDMDEAIEKGEAEQSEEEADEEDKA 1026
Query: 314 KKVYENYPTYDLTERKDFIKTTV 336
+ E + E +D++ V
Sbjct: 1027 EDAREEEYEPEKMEAEDYVMAVV 1049
Score = 33.1 bits (74), Expect = 0.37
Identities = 64/294 (21%), Positives = 122/294 (41%), Gaps = 42/294 (14%)
Query: 13 TPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDEL 72
T +P +KE E P++E ++ED+ ++EE+ K E + + K+ E
Sbjct: 642 TKVKPEDKKE-EKEKPKKEVAKKEDKTPIKKEEKPKK--------EEVKKEVKKEIKKEE 692
Query: 73 RNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKE--EMLKKFRNAMLKSICEVL 130
+ K + +KK V + EK V+ ++KE + +KK KS +
Sbjct: 693 KKEPKKEVKKETPPKEVKKEVKK-----EEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLS 747
Query: 131 DLER-SGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRT--- 186
+ ++ + + ++ K+ + +GKP K K K KKE ++ A T
Sbjct: 748 EAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGK---IKVIKKEGKAAEAVAAAVGTGAT 804
Query: 187 --------------KCPEILSDES--SSDEDEKKNKEESSDDEDKESEEEPPKKTAKREK 230
E+ ++ S SS ED K+ EE +E +++ P+ ++
Sbjct: 805 TAAVMAAAGIAAIGPAKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQLELIEDE 864
Query: 231 PKQKATSKSKKSV--KSANVKKADSSTTKKNQNSSKKESESEDSSDD-EPLIKK 281
K K T + V K V K + + + +++ E E E + ++ EP+ K+
Sbjct: 865 EKLKETEPVEAYVIQKEREVTKGPAESPDEGITTTEGEGECEQTPEELEPVEKQ 918
Score = 33.1 bits (74), Expect = 0.37
Identities = 27/116 (23%), Positives = 48/116 (41%), Gaps = 2/116 (1%)
Query: 156 GKPLPKS--KKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDE 213
GK L K +KT +K + SS +K+ P S + + ++ + +
Sbjct: 2232 GKALKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPK 2291
Query: 214 DKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESES 269
KES E+ K T E + K K++ +AN + S+ T + K ++S
Sbjct: 2292 KKESVEKAAKPTTTPEVKAARGEEKDKETKNAANASASKSAKTATAGPGTTKTTKS 2347
Score = 30.0 bits (66), Expect = 3.1
Identities = 36/176 (20%), Positives = 58/176 (32%), Gaps = 38/176 (21%)
Query: 153 KPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDD 212
K G+ ++ T S + S + + + +CP I +D + EDE +
Sbjct: 2136 KQQGRQCDETPPTSVSESAPSQTDSDVPPETE--ECPSITADANIDSEDESETIPTDKTV 2193
Query: 213 EDKESEEEPPKKTAKREKPKQ---------------------KATSKSKKSVKSANVKKA 251
K + P + P+ K K K K K
Sbjct: 2194 TYKHMDPPPAPVQDRSPSPRHPDVSMVDPEALAIEQNLGKALKKDLKEKTKTKKPGTKTK 2253
Query: 252 DSSTTKKNQNSSK------KESESEDSSD---------DEPLIKKLKKPPTDEELK 292
SS KK+ SK K + ++SSD + ++K KP T E+K
Sbjct: 2254 SSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPKKKESVEKAAKPTTTPEVK 2309
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 55.5 bits (132), Expect = 7e-08
Identities = 64/315 (20%), Positives = 129/315 (40%), Gaps = 39/315 (12%)
Query: 17 PASEKEPEMP--------GPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKK 68
PASE++ E P G +++ ++++ + ++EE+E+EK KG ++ + L+K K
Sbjct: 293 PASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLK 352
Query: 69 TDELRNLHKL--LYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSI 126
+E R + R + + +K + E+ + K+++E LKK + KS
Sbjct: 353 EEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQ 412
Query: 127 CEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRT 186
E + +E ++L PS LPK + + KR
Sbjct: 413 RE------ARARAEATLKLLQAQGVEVPSKDSLPKKRP--------------IYEDKKRK 452
Query: 187 KCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKA---------TS 237
K P+ L + S+ E E + E EE PP + E+ + A +
Sbjct: 453 KIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASD 512
Query: 238 KSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKK 297
+ + V+ V ++ + ++E E E+S ++E + + DEE ++ +
Sbjct: 513 EETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDE 572
Query: 298 LLASANLEEVTMKQI 312
+ L++ K++
Sbjct: 573 KDSGKTLDKKPSKEM 587
Score = 49.3 bits (116), Expect = 5e-06
Identities = 74/327 (22%), Positives = 123/327 (37%), Gaps = 47/327 (14%)
Query: 20 EKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDELRNLHKLL 79
+ + PGP ES E+D+ + + + K +K E ER KK+ +E L KL
Sbjct: 202 KNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKK-ERER------KKRDEEKAKLRKLK 254
Query: 80 YNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNS 139
E G K++E +KF +KS V + + +
Sbjct: 255 EKEE-----------------LETGKKDQSKQKESQRKFEEETVKSKVTV---DTGVIPA 294
Query: 140 ELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSD 199
K G K KK KG K+E+ +K T + +
Sbjct: 295 SEEKAETPTAAEDDNEGDKKKKDKKK-KKGEKEEKEKEKKKGPSKAT-VKAMQEALAKLK 352
Query: 200 EDEKKNKEESSD-------------DEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSA 246
E+E++ K E + +E++ +E+ +K K ++ K++ + K KS
Sbjct: 353 EEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQ 412
Query: 247 NVKKADSSTTKKNQNSSKKESESEDSSDDEPLI---KKLKKPPTDEELKETIKKLLASAN 303
+A + T K + E S+DS + I KK KK P E KE + + A
Sbjct: 413 REARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAA 472
Query: 304 LEEVTMKQICKKVYENYPTYDLTERKD 330
+E M+Q + E P + E +D
Sbjct: 473 VE--VMEQGVPEKEETPPPVEPEEEED 497
Score = 47.4 bits (111), Expect = 2e-05
Identities = 82/355 (23%), Positives = 140/355 (39%), Gaps = 63/355 (17%)
Query: 5 APAAEGEGTPTQPASEKEPEMPGPREESEEEE---DEDDEEEEEEE---KGKGQKLCEIE 58
A AAE EG A E+EP+ +++ E+++ DEDD +E EE + +G K + E
Sbjct: 21 ALAAEIEGAGA--AKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIK-ADRE 77
Query: 59 RIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEML--- 115
+ ++ +E + K + G S N + K K K EM
Sbjct: 78 TVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGS 137
Query: 116 ----------KKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKT 165
KK + KS + E NS+ +K + S ++
Sbjct: 138 DDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKE-----------RSRINSSGES 186
Query: 166 CSKGSKKERNSSGMARKAKRTKCPEILSDESSSDED-----------EKKNKEESSDDED 214
+ + ++ G + K P I S D EKK +E DE+
Sbjct: 187 GDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEE 246
Query: 215 KES----EEEPPKKTAKREKPKQKA--------TSKSKKSVKS----ANVKKADSSTTKK 258
K +E+ +T K+++ KQK T KSK +V + A+ +KA++ T +
Sbjct: 247 KAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAE 306
Query: 259 --NQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQ 311
N+ KK+ + + + E K+ KK P+ +K +++ LA EE K+
Sbjct: 307 DDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVK-AMQEALAKLKEEEERQKR 360
Score = 44.7 bits (104), Expect = 1e-04
Identities = 63/285 (22%), Positives = 106/285 (37%), Gaps = 35/285 (12%)
Query: 27 GPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTV 86
G ++S ++ D +E+E+ +K K ER S + DE + L +R G
Sbjct: 152 GKAQKSNKKWDGSEEDEDNSKKIK-------ERSRINSSGESGDES---DEFLQSRKGQK 201
Query: 87 SSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRIL 146
+ K G E +K K KK E + ER + E K
Sbjct: 202 KNQKNKPGPNIESGNEDDDASFKIKTVAQKK---------AEKKERERKKRDEEKAK--- 249
Query: 147 NFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEIL--SDESSS------ 198
+ + L KK SK + +R K+K T ++ S+E +
Sbjct: 250 ---LRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAE 306
Query: 199 --DEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTT 256
+E +KK K++ +KE +E+ KK + K + +K + K+ +
Sbjct: 307 DDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERI 366
Query: 257 KKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLAS 301
K+ + K E E ++ KK K+ E LK+ K L S
Sbjct: 367 KRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKS 411
Score = 38.1 bits (87), Expect = 0.011
Identities = 18/53 (33%), Positives = 29/53 (54%)
Query: 1 MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQK 53
M++ + EG ++ PE EE EEE++E +EEEEEE + +G +
Sbjct: 509 MASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSE 561
Score = 30.0 bits (66), Expect = 3.1
Identities = 23/87 (26%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 194 DESSSDEDEKKNKEESSDDEDKE--SEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKA 251
+ES +E+E+ E S DE+ E S+E+ KT + KP ++ +S S+ K+
Sbjct: 545 EESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDK-KPSKEMSSDSEYDSDDDRTKE- 602
Query: 252 DSSTTKKNQNSSKKESESEDSSDDEPL 278
+ + K + K+ E + + E L
Sbjct: 603 ERAYDKAKRRIEKRRLEHSKNVNTEKL 629
Score = 29.3 bits (64), Expect = 5.3
Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 3/48 (6%)
Query: 9 EGEGTPTQPASEKEPEMPGPREESEEEED---EDDEEEEEEEKGKGQK 53
E + P + E+E E E EEEE+ E E +EE+EK +K
Sbjct: 526 EVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEK 573
Score = 28.9 bits (63), Expect = 6.9
Identities = 31/129 (24%), Positives = 47/129 (36%), Gaps = 42/129 (32%)
Query: 202 EKKNKEESSDDEDKE--------------SEEEPPKKTAKREKPKQKATSKSKKSVK--- 244
++KNK E S +D + E+EP K K++K K+K +K
Sbjct: 4 KQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELE 63
Query: 245 ----SANVKKADSSTT------------------KKNQNSSKK---ESESEDSSDDEPLI 279
A KAD T KK Q K+ +++SE+ D +
Sbjct: 64 ELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKS 123
Query: 280 KKLKKPPTD 288
KK KP +
Sbjct: 124 KKTAKPKVE 132
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 55.1 bits (131), Expect = 9e-08
Identities = 71/309 (22%), Positives = 126/309 (40%), Gaps = 27/309 (8%)
Query: 9 EGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLC-EIERIHFFLSKK 67
EG+ KE E ++E E E+++ ++ +E + + E + +FF S +
Sbjct: 623 EGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDE 682
Query: 68 KTDELRNLH----------KLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKK 117
D N+ KL N S+ +K+V + F E+ + K+E K
Sbjct: 683 TEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKI----KKESEKS 738
Query: 118 FRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSS 177
FR +K + E + + +SE L + G L + + K K + S
Sbjct: 739 FREEKIKDLKEERENIPTDKDSEFTS--LGMSAIEESIGLHLVEKEIDIEKQEKHIKESK 796
Query: 178 GMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREK----PKQ 233
K + K +I E + E EKK K E ++DK E K +++K +
Sbjct: 797 EKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTE 856
Query: 234 KATSKSKKSVKSANVKKAD---SSTTKKNQNSSKKESESE---DSSDDEPLIKKLKKPPT 287
K + +KS +A +KK D S K ++ K++ E E S ++ L++K K
Sbjct: 857 KCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSD 916
Query: 288 DEELKETIK 296
+ E ++ K
Sbjct: 917 NSEYSKSEK 925
Score = 41.2 bits (95), Expect = 0.001
Identities = 65/293 (22%), Positives = 128/293 (43%), Gaps = 38/293 (12%)
Query: 64 LSKKKTDELRNLHKLLYNRPGTVS-SLKKNVGQF----SGFPFEKGSVQ---YKKKEEML 115
LS+K++ L+ H PG+ SL+ ++ ++ S F E SV+ +K+K +
Sbjct: 527 LSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSKHQ 586
Query: 116 KKFR-------NAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSK-KTCS 167
K F NA +K E S + + + L K K K K K
Sbjct: 587 KDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEI 646
Query: 168 KGSKKERNSSGMARKAKRT-------------KCPE----ILSDESSSDEDEKKNKEESS 210
+G K++ + A++ +R+ K E L+ E S EKK+K E +
Sbjct: 647 EGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKN 706
Query: 211 DDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVK-----KADSSTTKKNQNSSKK 265
+DK ++E+ K ++ + K +S+KS + +K + + T K ++ +S
Sbjct: 707 IKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLG 766
Query: 266 ESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYE 318
S E+S + K++ ++ +KE+ +K + ++E ++++ +K +E
Sbjct: 767 MSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFE 819
Score = 37.7 bits (86), Expect = 0.015
Identities = 65/300 (21%), Positives = 120/300 (40%), Gaps = 39/300 (13%)
Query: 20 EKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSK-----KKTDELRN 74
++ E P R + +E++ E E + E++ K + + E+ LS+ K+ D+L +
Sbjct: 793 KESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYS 852
Query: 75 LHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLER 134
H ++ G S KN +K + K +E+M +K D E+
Sbjct: 853 HHTEKCHKEGEKS---KNTAAI-----KKTDDREKSREKMDRKH------------DKEK 892
Query: 135 SGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSD 194
L + LM K + K+ KG KE++ + +K K I
Sbjct: 893 PEKERHLAESKEKHLMEKKNKQSDNSEYSKS-EKGKNKEKDRE-LDKKEKSRDKESINIT 950
Query: 195 ESSSDEDEKKNKEESSDDED-------KESEEEPPKKT--AKREKPKQKATSKSKKSVKS 245
S ++EKK+ + KE ++ P KT K + K K + K+ K
Sbjct: 951 NSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKERDKH 1010
Query: 246 ANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLE 305
+ + +S K++ K S S D P K K+ D+ ++ + +++L+ +LE
Sbjct: 1011 KDKIQINSLLKLKSEADKPKPKSSPASKDTRP---KEKRLVNDDLMQTSFERMLSLKDLE 1067
Score = 37.0 bits (84), Expect = 0.025
Identities = 61/290 (21%), Positives = 117/290 (40%), Gaps = 26/290 (8%)
Query: 9 EGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEE-----------EEKGKGQKLCEI 57
EGE + A +K + RE+ + + D++ E+E E+K K E
Sbjct: 861 EGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEY 920
Query: 58 ERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKK 117
+ +K+K EL K +++ K + + Q++K + +K
Sbjct: 921 SKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEK 980
Query: 118 FRNAMLKSIC------EVLDLERSGVNSELVKRI-LNFLMHPKPSG-KPLPKSKKTCSKG 169
++ LK+ + D++R + +I +N L+ K KP PKS
Sbjct: 981 TKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDT 1040
Query: 170 SKKERNSSGMARKAKRTKCPEILSDESSSDED-EKKNKEESSDDEDKESEEEPPKKTAKR 228
KE+ + +T +LS + E KK+KE+ E + + +
Sbjct: 1041 RPKEKRL--VNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIK 1098
Query: 229 EKPKQKAT---SKSKKSVKSANVKKADSSTTKKN-QNSSKKESESEDSSD 274
+K K K T SK+K+ +S + + D+ T +K +++ S+S D+ +
Sbjct: 1099 DKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSNRSQSVDTKN 1148
Score = 32.3 bits (72), Expect = 0.63
Identities = 37/151 (24%), Positives = 57/151 (37%), Gaps = 17/151 (11%)
Query: 150 MHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAK---RTKCPEILSDESSSDEDEKKNK 206
M KP G+ + SK K ER+ K K + K P +S +N+
Sbjct: 21 MVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMKRKLPFTISPS--------RNE 72
Query: 207 EESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE 266
E SD E +E P KK K+E +K+T S + +K + + + +
Sbjct: 73 ERDSDTE----KEGPEKKKTKKEAGNKKSTPVSILFGYPLSERKQMALLMQMTARDNSPD 128
Query: 267 SESEDSSDDEPLIKKLKKPPTDEELKETIKK 297
S S P K K P + K+ + K
Sbjct: 129 STPNHPSQTTPAQK--KTPSSSSRQKDKVNK 157
Score = 32.3 bits (72), Expect = 0.63
Identities = 61/288 (21%), Positives = 109/288 (37%), Gaps = 53/288 (18%)
Query: 30 EESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDELRNLHKL---------LY 80
+E +E+ D ++E E+ + +K+ +++ + K E +L L
Sbjct: 720 KERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLV 779
Query: 81 NRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKK-FRNAML-----KSICEVLDLER 134
+ + +K++ + P ++ ++ K E+M +K F KS + LDL
Sbjct: 780 EKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDL-- 837
Query: 135 SGVNSELVKRILN----FLMHPKPSGKPLPKSKKTCS--KGSKKERNSSGMARKAKRTKC 188
SE V +I + H + K KSK T + K +E++ M RK + K
Sbjct: 838 ----SECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEK- 892
Query: 189 PEI------------------LSDESSSDEDEK-KNKEESSD------DEDKESEEEPPK 223
PE SD S + EK KNKE+ + DKES
Sbjct: 893 PEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNS 952
Query: 224 KTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESED 271
K + EK + K ++K+ K + +K+ + +D
Sbjct: 953 KHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKD 1000
Score = 31.2 bits (69), Expect = 1.4
Identities = 27/110 (24%), Positives = 54/110 (49%), Gaps = 6/110 (5%)
Query: 160 PKSKKTCSKGSKKERNSSGMARKAKRTKCPEIL-SDESSSDEDEKKNKEESSD----DED 214
P+++KT +K+E+ + K+K+ K +L S SSDE+ +NK+ S+ E
Sbjct: 368 PEAEKT-HLFAKQEKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQNKKISTSCSVIPET 426
Query: 215 KESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSK 264
S+ + K+ + KQK K K ++ N + + K+ + +++
Sbjct: 427 SNSDMQTKKEYVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTR 476
Score = 28.9 bits (63), Expect = 6.9
Identities = 20/80 (25%), Positives = 34/80 (42%), Gaps = 2/80 (2%)
Query: 207 EESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKK--NQNSSK 264
+ + D D E+P + +K + T K ++S S +K+ S K + S+
Sbjct: 11 QSENSDSDSNMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMKRKLPFTISPSR 70
Query: 265 KESESEDSSDDEPLIKKLKK 284
E D+ + P KK KK
Sbjct: 71 NEERDSDTEKEGPEKKKTKK 90
Score = 28.5 bits (62), Expect = 9.1
Identities = 34/134 (25%), Positives = 59/134 (44%), Gaps = 19/134 (14%)
Query: 185 RTKCPEILSD-ESSSDEDEKKNK----------EESSDDEDKESEEEPPKKTAKREKPKQ 233
+T P L + E D+DE+ NK E+ ++ E E E AK+EK
Sbjct: 328 KTPLPSALDEYEFKDDDDEEINKMIDDRHILRKEQRKEN---EPEAEKTHLFAKQEKAFY 384
Query: 234 KATSKSKKSVKSANVKKADSSTTKKNQNSSKKESES----EDSSDDEPLIKKLKKPPTDE 289
+ KSKK K + V + + ++ + +KK S S ++S+ + KK +
Sbjct: 385 PKSFKSKKQ-KPSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEH 443
Query: 290 ELKETIKKLLASAN 303
+ K +K+ L + N
Sbjct: 444 KQKGKVKRKLKNQN 457
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 55.1 bits (131), Expect = 9e-08
Identities = 71/309 (22%), Positives = 126/309 (40%), Gaps = 27/309 (8%)
Query: 9 EGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLC-EIERIHFFLSKK 67
EG+ KE E ++E E E+++ ++ +E + + E + +FF S +
Sbjct: 646 EGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDE 705
Query: 68 KTDELRNLH----------KLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKK 117
D N+ KL N S+ +K+V + F E+ + K+E K
Sbjct: 706 TEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKI----KKESEKS 761
Query: 118 FRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSS 177
FR +K + E + + +SE L + G L + + K K + S
Sbjct: 762 FREEKIKDLKEERENIPTDKDSEFTS--LGMSAIEESIGLHLVEKEIDIEKQEKHIKESK 819
Query: 178 GMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREK----PKQ 233
K + K +I E + E EKK K E ++DK E K +++K +
Sbjct: 820 EKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTE 879
Query: 234 KATSKSKKSVKSANVKKAD---SSTTKKNQNSSKKESESE---DSSDDEPLIKKLKKPPT 287
K + +KS +A +KK D S K ++ K++ E E S ++ L++K K
Sbjct: 880 KCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSD 939
Query: 288 DEELKETIK 296
+ E ++ K
Sbjct: 940 NSEYSKSEK 948
Score = 41.2 bits (95), Expect = 0.001
Identities = 65/293 (22%), Positives = 128/293 (43%), Gaps = 38/293 (12%)
Query: 64 LSKKKTDELRNLHKLLYNRPGTVS-SLKKNVGQF----SGFPFEKGSVQ---YKKKEEML 115
LS+K++ L+ H PG+ SL+ ++ ++ S F E SV+ +K+K +
Sbjct: 550 LSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSKHQ 609
Query: 116 KKFR-------NAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSK-KTCS 167
K F NA +K E S + + + L K K K K K
Sbjct: 610 KDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEI 669
Query: 168 KGSKKERNSSGMARKAKRT-------------KCPE----ILSDESSSDEDEKKNKEESS 210
+G K++ + A++ +R+ K E L+ E S EKK+K E +
Sbjct: 670 EGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKN 729
Query: 211 DDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVK-----KADSSTTKKNQNSSKK 265
+DK ++E+ K ++ + K +S+KS + +K + + T K ++ +S
Sbjct: 730 IKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLG 789
Query: 266 ESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYE 318
S E+S + K++ ++ +KE+ +K + ++E ++++ +K +E
Sbjct: 790 MSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFE 842
Score = 37.7 bits (86), Expect = 0.015
Identities = 65/300 (21%), Positives = 120/300 (40%), Gaps = 39/300 (13%)
Query: 20 EKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSK-----KKTDELRN 74
++ E P R + +E++ E E + E++ K + + E+ LS+ K+ D+L +
Sbjct: 816 KESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYS 875
Query: 75 LHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLER 134
H ++ G S KN +K + K +E+M +K D E+
Sbjct: 876 HHTEKCHKEGEKS---KNTAAI-----KKTDDREKSREKMDRKH------------DKEK 915
Query: 135 SGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSD 194
L + LM K + K+ KG KE++ + +K K I
Sbjct: 916 PEKERHLAESKEKHLMEKKNKQSDNSEYSKS-EKGKNKEKDRE-LDKKEKSRDKESINIT 973
Query: 195 ESSSDEDEKKNKEESSDDED-------KESEEEPPKKT--AKREKPKQKATSKSKKSVKS 245
S ++EKK+ + KE ++ P KT K + K K + K+ K
Sbjct: 974 NSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKERDKH 1033
Query: 246 ANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLE 305
+ + +S K++ K S S D P K K+ D+ ++ + +++L+ +LE
Sbjct: 1034 KDKIQINSLLKLKSEADKPKPKSSPASKDTRP---KEKRLVNDDLMQTSFERMLSLKDLE 1090
Score = 37.0 bits (84), Expect = 0.025
Identities = 61/290 (21%), Positives = 117/290 (40%), Gaps = 26/290 (8%)
Query: 9 EGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEE-----------EEKGKGQKLCEI 57
EGE + A +K + RE+ + + D++ E+E E+K K E
Sbjct: 884 EGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEY 943
Query: 58 ERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKK 117
+ +K+K EL K +++ K + + Q++K + +K
Sbjct: 944 SKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEK 1003
Query: 118 FRNAMLKSIC------EVLDLERSGVNSELVKRI-LNFLMHPKPSG-KPLPKSKKTCSKG 169
++ LK+ + D++R + +I +N L+ K KP PKS
Sbjct: 1004 TKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDT 1063
Query: 170 SKKERNSSGMARKAKRTKCPEILSDESSSDED-EKKNKEESSDDEDKESEEEPPKKTAKR 228
KE+ + +T +LS + E KK+KE+ E + + +
Sbjct: 1064 RPKEKRL--VNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIK 1121
Query: 229 EKPKQKAT---SKSKKSVKSANVKKADSSTTKKN-QNSSKKESESEDSSD 274
+K K K T SK+K+ +S + + D+ T +K +++ S+S D+ +
Sbjct: 1122 DKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSNRSQSVDTKN 1171
Score = 32.3 bits (72), Expect = 0.63
Identities = 61/288 (21%), Positives = 109/288 (37%), Gaps = 53/288 (18%)
Query: 30 EESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDELRNLHKL---------LY 80
+E +E+ D ++E E+ + +K+ +++ + K E +L L
Sbjct: 743 KERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLV 802
Query: 81 NRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKK-FRNAML-----KSICEVLDLER 134
+ + +K++ + P ++ ++ K E+M +K F KS + LDL
Sbjct: 803 EKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDL-- 860
Query: 135 SGVNSELVKRILN----FLMHPKPSGKPLPKSKKTCS--KGSKKERNSSGMARKAKRTKC 188
SE V +I + H + K KSK T + K +E++ M RK + K
Sbjct: 861 ----SECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEK- 915
Query: 189 PEI------------------LSDESSSDEDEK-KNKEESSD------DEDKESEEEPPK 223
PE SD S + EK KNKE+ + DKES
Sbjct: 916 PEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNS 975
Query: 224 KTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESED 271
K + EK + K ++K+ K + +K+ + +D
Sbjct: 976 KHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKD 1023
Score = 31.2 bits (69), Expect = 1.4
Identities = 27/110 (24%), Positives = 54/110 (49%), Gaps = 6/110 (5%)
Query: 160 PKSKKTCSKGSKKERNSSGMARKAKRTKCPEIL-SDESSSDEDEKKNKEESSD----DED 214
P+++KT +K+E+ + K+K+ K +L S SSDE+ +NK+ S+ E
Sbjct: 391 PEAEKT-HLFAKQEKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQNKKISTSCSVIPET 449
Query: 215 KESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSK 264
S+ + K+ + KQK K K ++ N + + K+ + +++
Sbjct: 450 SNSDMQTKKEYVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTR 499
Score = 30.0 bits (66), Expect = 3.1
Identities = 34/162 (20%), Positives = 57/162 (35%), Gaps = 16/162 (9%)
Query: 150 MHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAK---RTKCPEILSDESSSDEDEKKNK 206
M KP G+ + SK K ER+ K K + K P +S + + D +
Sbjct: 21 MVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMKRKLPFTISPSRNEERDSDTDS 80
Query: 207 EESSDDED-----------KESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSST 255
+ E+ +E P KK K+E +K+T S + +K +
Sbjct: 81 DPGHTSENWGERLISSYRTYSEKEGPEKKKTKKEAGNKKSTPVSILFGYPLSERKQMALL 140
Query: 256 TKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKK 297
+ + +S S P K K P + K+ + K
Sbjct: 141 MQMTARDNSPDSTPNHPSQTTPAQK--KTPSSSSRQKDKVNK 180
Score = 28.5 bits (62), Expect = 9.1
Identities = 34/134 (25%), Positives = 59/134 (44%), Gaps = 19/134 (14%)
Query: 185 RTKCPEILSD-ESSSDEDEKKNK----------EESSDDEDKESEEEPPKKTAKREKPKQ 233
+T P L + E D+DE+ NK E+ ++ E E E AK+EK
Sbjct: 351 KTPLPSALDEYEFKDDDDEEINKMIDDRHILRKEQRKEN---EPEAEKTHLFAKQEKAFY 407
Query: 234 KATSKSKKSVKSANVKKADSSTTKKNQNSSKKESES----EDSSDDEPLIKKLKKPPTDE 289
+ KSKK K + V + + ++ + +KK S S ++S+ + KK +
Sbjct: 408 PKSFKSKKQ-KPSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEH 466
Query: 290 ELKETIKKLLASAN 303
+ K +K+ L + N
Sbjct: 467 KQKGKVKRKLKNQN 480
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 54.7 bits (130), Expect = 1e-07
Identities = 34/111 (30%), Positives = 53/111 (47%), Gaps = 1/111 (0%)
Query: 202 EKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSK-SKKSVKSANVKKADSSTTKKNQ 260
+KK KE +E +E+EEE K+ ++EK K+K K KK K +K KK +
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63
Query: 261 NSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQ 311
KK+ E E+ ++E ++ K+ EE + KK EE K+
Sbjct: 64 RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114
Score = 53.9 bits (128), Expect = 2e-07
Identities = 28/113 (24%), Positives = 55/113 (48%)
Query: 181 RKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSK 240
+K K+ K E + ++E+E+K + ++K E+E KKT + EK K+K + K
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 241 KSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKE 293
+ K K+ + ++ + +KE E ++ KK ++ +EE K+
Sbjct: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114
Score = 50.1 bits (118), Expect = 3e-06
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 9/98 (9%)
Query: 153 KPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDD 212
K K K KKT +KE+ RK KR K +E+E++ +EE ++
Sbjct: 34 KEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKK---------KKEEEEREEEEEEEEE 84
Query: 213 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKK 250
E +E E+E ++ K++K ++K + KK + KK
Sbjct: 85 EKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122
Score = 46.6 bits (109), Expect = 3e-05
Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 168 KGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEK------KNKEESSDDEDKESEEEP 221
+G +KE+ K K+ K E + +E++K K KEE +E++E EEE
Sbjct: 26 EGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEE 85
Query: 222 PKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKK 258
++ K E ++K K ++ + KK TKK
Sbjct: 86 KEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122
Score = 43.5 bits (101), Expect = 3e-04
Identities = 27/124 (21%), Positives = 54/124 (43%), Gaps = 3/124 (2%)
Query: 161 KSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEE 220
K KK + + E + K K E ++ E +KK KE ++ KE EEE
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKET---EKRKEKEEE 58
Query: 221 PPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIK 280
K+ KR+K K++ + ++ + ++ + ++ + K+ + E+ + +
Sbjct: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118
Query: 281 KLKK 284
K KK
Sbjct: 119 KTKK 122
Score = 41.2 bits (95), Expect = 0.001
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 6/88 (6%)
Query: 153 KPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDD 212
K K K K K +KE RK K+ K E +E +E+EK+ +E+
Sbjct: 36 KRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGR 95
Query: 213 EDKE------SEEEPPKKTAKREKPKQK 234
K+ EEE KK +R K K+K
Sbjct: 96 RRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 38.1 bits (87), Expect = 0.011
Identities = 25/121 (20%), Positives = 55/121 (45%), Gaps = 11/121 (9%)
Query: 181 RKAKRTKCPEILSDESSSDEDEK------KNKEESSDDEDKESEEEPPKKTAKRE----- 229
+K K+ + E E + +E+EK K KE+ + E K+ +E K+ K E
Sbjct: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62
Query: 230 KPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDE 289
K K+K + ++ + ++ + +K + +K+ + ++E KK ++ T +
Sbjct: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122
Query: 290 E 290
+
Sbjct: 123 K 123
Score = 37.0 bits (84), Expect = 0.025
Identities = 15/24 (62%), Positives = 22/24 (91%)
Query: 30 EESEEEEDEDDEEEEEEEKGKGQK 53
EE EEEE+E++EE+EEEEK +G++
Sbjct: 73 EEREEEEEEEEEEKEEEEKEEGRR 96
Score = 34.3 bits (77), Expect = 0.16
Identities = 19/43 (44%), Positives = 27/43 (62%), Gaps = 4/43 (9%)
Query: 15 TQPASEKEPEMPGPR----EESEEEEDEDDEEEEEEEKGKGQK 53
T+ EKE E + ++ EEEE E++EEEEEEEK + +K
Sbjct: 49 TEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEK 91
Score = 34.3 bits (77), Expect = 0.16
Identities = 19/40 (47%), Positives = 25/40 (62%)
Query: 29 REESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKK 68
REE EEEE+E+ EEEE+EE + +K + R KKK
Sbjct: 75 REEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114
Score = 32.3 bits (72), Expect = 0.63
Identities = 15/34 (44%), Positives = 23/34 (67%)
Query: 20 EKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQK 53
+K+ E EE EEEE+E +EEE+EE + + +K
Sbjct: 67 KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKK 100
Score = 32.0 bits (71), Expect = 0.82
Identities = 16/45 (35%), Positives = 26/45 (57%)
Query: 9 EGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQK 53
E E + +K+ E EE EEEE++++EE+EE + K +K
Sbjct: 57 EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKK 101
Score = 31.2 bits (69), Expect = 1.4
Identities = 15/34 (44%), Positives = 21/34 (61%)
Query: 20 EKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQK 53
+KE E EE EEEE E++E+EE + K +K
Sbjct: 69 KKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKK 102
Score = 30.8 bits (68), Expect = 1.8
Identities = 18/43 (41%), Positives = 28/43 (65%), Gaps = 1/43 (2%)
Query: 29 REESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDE 71
++E+EE E+ ++ EEEEE++GK +K E+ KKKT E
Sbjct: 7 KKETEETEETEETEEEEEKEGK-RKEKRKEKRKEKEKKKKTKE 48
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 54.7 bits (130), Expect = 1e-07
Identities = 37/141 (26%), Positives = 69/141 (48%), Gaps = 7/141 (4%)
Query: 153 KPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDD 212
+P KP PK + K K R S + + + S ESSS++DE+ ++E+ D+
Sbjct: 936 RPGTKP-PKRDEERGKTQGKHRKSFALDSEGEEA------SQESSSEKDEEDDEEDEEDE 988
Query: 213 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDS 272
+ +E+ + K+T + +++ S SK S+ + + + DS++ ++ +SS S S S
Sbjct: 989 DREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSS 1048
Query: 273 SDDEPLIKKLKKPPTDEELKE 293
S + DEE +E
Sbjct: 1049 SSSSSSSSSSESSSEDEEEEE 1069
Score = 42.0 bits (97), Expect = 8e-04
Identities = 29/101 (28%), Positives = 48/101 (47%), Gaps = 14/101 (13%)
Query: 182 KAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEE------PPKKTAKREKPKQKA 235
K KR + EI E+S ++ + + D++D E E+E P K KR++ + K
Sbjct: 894 KVKRKEPSEI--SEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKT 951
Query: 236 TSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDE 276
K +KS DS + +Q SS ++ E +D D+E
Sbjct: 952 QGKHRKSF------ALDSEGEEASQESSSEKDEEDDEEDEE 986
Score = 33.5 bits (75), Expect = 0.28
Identities = 45/221 (20%), Positives = 82/221 (37%), Gaps = 38/221 (17%)
Query: 14 PTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGK-GQKLCEIERIHFFLSKKKTDEL 72
P++ + E + P P +EE+ED+ ++E+E E G+ G K K DE
Sbjct: 900 PSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTK------------PPKRDEE 947
Query: 73 RNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDL 132
R + + + + S + Q S ++ + +++E ++ + K EV D
Sbjct: 948 RGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKE-TEVSDG 1006
Query: 133 ERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEIL 192
E +S SK + S E +S+ + + +
Sbjct: 1007 EDEESDS---------------------SSKCSLYADSDGENDSTSDSESSSSSSSS--- 1042
Query: 193 SDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQ 233
S SSS + S ED+E EE P + P++
Sbjct: 1043 SSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPRE 1083
Score = 33.5 bits (75), Expect = 0.28
Identities = 21/47 (44%), Positives = 25/47 (53%), Gaps = 4/47 (8%)
Query: 4 SAPAAEGEGTPTQPASEKEPEMPGP----REESEEEEDEDDEEEEEE 46
S+PA E P +E E P REE EEE +E+ EEEEEE
Sbjct: 1329 SSPADEVLEAPEVVVAEAEEPKPQQLQQQREEGEEEGEEEGEEEEEE 1375
Score = 33.1 bits (74), Expect = 0.37
Identities = 22/74 (29%), Positives = 28/74 (37%), Gaps = 30/74 (40%)
Query: 4 SAPAAEGEGTPTQPASEKEPEMPGPR------------------------------EESE 33
S PA E E P Q EP PG + E S
Sbjct: 915 STPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSS 974
Query: 34 EEEDEDDEEEEEEE 47
E+++EDDEE+EE+E
Sbjct: 975 EKDEEDDEEDEEDE 988
Score = 30.0 bits (66), Expect = 3.1
Identities = 15/45 (33%), Positives = 24/45 (53%)
Query: 8 AEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQ 52
+EGE + +SEK+ E EE E+ E+ D ++E E G+
Sbjct: 963 SEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGE 1007
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 54.3 bits (129), Expect = 2e-07
Identities = 44/145 (30%), Positives = 64/145 (44%), Gaps = 11/145 (7%)
Query: 152 PKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSD 211
P S KP P S K+ S R ++R + E+ + E KN E SD
Sbjct: 107 PYGSDKPWP------SLLDKEREESLRQKRLSERERIGELGAPEVWGLSP--KNPEPDSD 158
Query: 212 DEDKESEEEPPKKTAKR---EKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESE 268
+ +EEP K T E+ K+K +S+SK+ K KK+ KK S +S+
Sbjct: 159 EHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSD 218
Query: 269 SEDSSDDEPLIKKLKKPPTDEELKE 293
SE S DE ++ KK E+ K+
Sbjct: 219 SETDSSDEDNKRRAKKAKKKEKKKK 243
Score = 52.8 bits (125), Expect = 4e-07
Identities = 39/116 (33%), Positives = 54/116 (46%), Gaps = 16/116 (13%)
Query: 160 PKSKKTCSKGS---KKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKE 216
PK T + S KK+++S R KR K + SS KK E+S D D E
Sbjct: 168 PKKSTTSASTSEEEKKKKSSRSKERSKKRRK-------KKSSKRKHKKYSEDSDSDSDSE 220
Query: 217 --SEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESE 270
S +E K+ AK+ K K+K K K KK + K++ +SS KES+ E
Sbjct: 221 TDSSDEDNKRRAKKAKKKEKKKKHRSKKYK----KKRSKKSRKESSDSSSKESQEE 272
Score = 45.8 bits (107), Expect = 5e-05
Identities = 37/143 (25%), Positives = 60/143 (41%), Gaps = 19/143 (13%)
Query: 152 PKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSD 211
PK S S++ K S + + S RK K +K + S D D + E S
Sbjct: 168 PKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKH---KKYSEDSDSDSDSETDSS 224
Query: 212 DED-----KESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE 266
DED K+++++ KK + +K K+K + KS+K ++ K++ + K
Sbjct: 225 DEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKA 284
Query: 267 SESED-----------SSDDEPL 278
E D S DD+PL
Sbjct: 285 EEPSDLIGPEAPKTLTSQDDKPL 307
>gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens]
Length = 872
Score = 54.3 bits (129), Expect = 2e-07
Identities = 41/171 (23%), Positives = 82/171 (47%), Gaps = 15/171 (8%)
Query: 120 NAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGM 179
+A++K + + G ++L RIL + +GKP SKK ++ R +G+
Sbjct: 244 DAIVKMLDAAVIKMEGGTENDL--RILEQEEEEEQAGKPGEPSKK------EEGRAGAGL 295
Query: 180 ARKAKRTKCPEILSDESSSDEDEKKNKEESS-DDEDKESEEEPPKKTAKREKPKQKATSK 238
++T +D+ ED K+ + +SS DD+ K+SE + K+ K + K+ S
Sbjct: 296 GDGERKT------NDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSS 349
Query: 239 SKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDE 289
K++ K + D + ++++ S+ E+ + E +K+ +KP +E
Sbjct: 350 KKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEE 400
Score = 39.7 bits (91), Expect = 0.004
Identities = 22/82 (26%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Query: 161 KSKKTCSKGSKKER--NSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESE 218
K+KK+ G K+E+ +S A+K+ + + + D+S + +++ ES + +E +
Sbjct: 324 KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEK 383
Query: 219 EEPPKKTAKREKPKQKATSKSK 240
EE + ++EKPK++ K K
Sbjct: 384 EEAEEALKEKEKPKEEEWEKPK 405
Score = 30.0 bits (66), Expect = 3.1
Identities = 25/97 (25%), Positives = 45/97 (46%), Gaps = 9/97 (9%)
Query: 161 KSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEE- 219
++KK+ K ++K + E ES E+EK+ EE+ +++K EE
Sbjct: 344 EAKKSSKKRNRKHSGDDSFDEGSVSESESE---SESGQAEEEKEEAEEALKEKEKPKEEE 400
Query: 220 -EPPKKTAKRE---KPKQKATSKSKKSVKSANVKKAD 252
E PK A E +P K S +++ + N+ +A+
Sbjct: 401 WEKPKDAAGLECKPRPLHKTCSLFMRNI-APNISRAE 436
>gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens]
Length = 876
Score = 54.3 bits (129), Expect = 2e-07
Identities = 41/171 (23%), Positives = 82/171 (47%), Gaps = 15/171 (8%)
Query: 120 NAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGM 179
+A++K + + G ++L RIL + +GKP SKK ++ R +G+
Sbjct: 244 DAIVKMLDAAVIKMEGGTENDL--RILEQEEEEEQAGKPGEPSKK------EEGRAGAGL 295
Query: 180 ARKAKRTKCPEILSDESSSDEDEKKNKEESS-DDEDKESEEEPPKKTAKREKPKQKATSK 238
++T +D+ ED K+ + +SS DD+ K+SE + K+ K + K+ S
Sbjct: 296 GDGERKT------NDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSS 349
Query: 239 SKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDE 289
K++ K + D + ++++ S+ E+ + E +K+ +KP +E
Sbjct: 350 KKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEE 400
Score = 39.7 bits (91), Expect = 0.004
Identities = 22/82 (26%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Query: 161 KSKKTCSKGSKKER--NSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESE 218
K+KK+ G K+E+ +S A+K+ + + + D+S + +++ ES + +E +
Sbjct: 324 KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEK 383
Query: 219 EEPPKKTAKREKPKQKATSKSK 240
EE + ++EKPK++ K K
Sbjct: 384 EEAEEALKEKEKPKEEEWEKPK 405
Score = 30.0 bits (66), Expect = 3.1
Identities = 25/97 (25%), Positives = 45/97 (46%), Gaps = 9/97 (9%)
Query: 161 KSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEE- 219
++KK+ K ++K + E ES E+EK+ EE+ +++K EE
Sbjct: 344 EAKKSSKKRNRKHSGDDSFDEGSVSESESE---SESGQAEEEKEEAEEALKEKEKPKEEE 400
Query: 220 -EPPKKTAKRE---KPKQKATSKSKKSVKSANVKKAD 252
E PK A E +P K S +++ + N+ +A+
Sbjct: 401 WEKPKDAAGLECKPRPLHKTCSLFMRNI-APNISRAE 436
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 54.3 bits (129), Expect = 2e-07
Identities = 38/163 (23%), Positives = 77/163 (47%), Gaps = 15/163 (9%)
Query: 160 PKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSS----DEDEKKNKEESSDDEDK 215
P S + S+ R S +R +R+K P S K +++ +D++K
Sbjct: 261 PSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEK 320
Query: 216 ESEEEPPK--------KTAKREKPKQKATS--KSKKSVKSANVKKADSSTTKKNQNSSKK 265
+ + PPK ++A RE+ ++++ S +S K +S K + S + ++++ KK
Sbjct: 321 KRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKK 380
Query: 266 ESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVT 308
+ + E S D+ KK D+E K+ +K + ++++VT
Sbjct: 381 DKDKERSRDERERSTSKKKKSKDKE-KDRERKSESDKDVKQVT 422
Score = 50.8 bits (120), Expect = 2e-06
Identities = 34/148 (22%), Positives = 67/148 (45%), Gaps = 3/148 (2%)
Query: 153 KPSGKPLPKSKKTC--SKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESS 210
K K PKS T S+ + +ER + K P + S +++K+E
Sbjct: 320 KKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKK 379
Query: 211 DDEDKE-SEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESES 269
D+DKE S +E + T+K++K K K + +KS +VK+ ++ Q ++ +
Sbjct: 380 KDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKK 439
Query: 270 EDSSDDEPLIKKLKKPPTDEELKETIKK 297
E+ E K K+ ++ +++++
Sbjct: 440 EEKKPIETGSPKTKECSVEKGTGDSLRE 467
Score = 35.8 bits (81), Expect = 0.057
Identities = 41/148 (27%), Positives = 57/148 (38%), Gaps = 19/148 (12%)
Query: 134 RSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARK-AKRTKCPEIL 192
RSG S R + PS + K KK K KER+ R +K+ K +
Sbjct: 349 RSGTRSPKKPRSPKRKLSRSPSPRRHKKEKK---KDKDKERSRDERERSTSKKKKSKDKE 405
Query: 193 SD---ESSSDEDEKKNKEESSDDE---DKESEEEPPKKTAKREKPKQKATSKSKKSVKSA 246
D +S SD+D K+ + ++E D E E++ KK + PK K S K + S
Sbjct: 406 KDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSL 465
Query: 247 NVKKADSSTTKKNQNSSKKESESEDSSD 274
K N E D SD
Sbjct: 466 RESKV---------NGDDHHEEDMDMSD 484
Score = 33.5 bits (75), Expect = 0.28
Identities = 24/123 (19%), Positives = 56/123 (45%), Gaps = 5/123 (4%)
Query: 167 SKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTA 226
S K + +S + KR + + L ++ + D+K+ K S + P +
Sbjct: 207 SPSLKSDTSSKEIEEAMKRVREAQSLIS-AAIEPDKKEEKRRHSRSRSRSRRRRTPSSSR 265
Query: 227 ---KREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLK 283
R + ++++ SKS+ +S + ++ S + ++ + S+ S++ D ++ K+ K
Sbjct: 266 HRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRR-SRSTSKTRDKKKEDKEKKRSK 324
Query: 284 KPP 286
PP
Sbjct: 325 TPP 327
>gi|224591430 Ly1 antibody reactive homolog [Homo sapiens]
Length = 379
Score = 53.9 bits (128), Expect = 2e-07
Identities = 66/266 (24%), Positives = 108/266 (40%), Gaps = 29/266 (10%)
Query: 79 LYNRPGT---VSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERS 135
L RP V L + + F P +K Q K LK ++L + + +
Sbjct: 84 LIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNS-LKVHNESILDQVWNIFSEASN 142
Query: 136 G--VNSELVKRILNFLMHPKPS-GKPLPKSKKTCS-------KGSKKERNSSGMARKAKR 185
VN E +R L+ + +P +P SK + K +K+ER +K KR
Sbjct: 143 SEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQ-KKRKR 201
Query: 186 TKCPEILSDESSSDEDEKKNKEESSDDEDKES--EEEPPKKTAKREKPKQKATSKSKKSV 243
K L + + ++K K + + D E+ EE P + ++ K+K K S
Sbjct: 202 EKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASE 261
Query: 244 KSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDE-------ELKETIK 296
+ A V K+ + S+ E++S+ P + +P DE K TIK
Sbjct: 262 EEARV-----GAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIK 316
Query: 297 KLLASANLEEVTMKQICKKVYENYPT 322
+L A E+T+K++ KKV Y T
Sbjct: 317 AILKQAPDNEITIKKLRKKVLAQYYT 342
>gi|8923398 Ly1 antibody reactive homolog [Homo sapiens]
Length = 379
Score = 53.9 bits (128), Expect = 2e-07
Identities = 66/266 (24%), Positives = 108/266 (40%), Gaps = 29/266 (10%)
Query: 79 LYNRPGT---VSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERS 135
L RP V L + + F P +K Q K LK ++L + + +
Sbjct: 84 LIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNS-LKVHNESILDQVWNIFSEASN 142
Query: 136 G--VNSELVKRILNFLMHPKPS-GKPLPKSKKTCS-------KGSKKERNSSGMARKAKR 185
VN E +R L+ + +P +P SK + K +K+ER +K KR
Sbjct: 143 SEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQ-KKRKR 201
Query: 186 TKCPEILSDESSSDEDEKKNKEESSDDEDKES--EEEPPKKTAKREKPKQKATSKSKKSV 243
K L + + ++K K + + D E+ EE P + ++ K+K K S
Sbjct: 202 EKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASE 261
Query: 244 KSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDE-------ELKETIK 296
+ A V K+ + S+ E++S+ P + +P DE K TIK
Sbjct: 262 EEARV-----GAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIK 316
Query: 297 KLLASANLEEVTMKQICKKVYENYPT 322
+L A E+T+K++ KKV Y T
Sbjct: 317 AILKQAPDNEITIKKLRKKVLAQYYT 342
>gi|153791492 eukaryotic translation initiation factor 3, subunit
C-like [Homo sapiens]
Length = 914
Score = 53.5 bits (127), Expect = 3e-07
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 18/148 (12%)
Query: 168 KGSKKERNSSGMARKAKRTKCPEILSD------------ESSSDEDEKKNKEESSDDEDK 215
+G KK ++ A R K + D E S+DED +KN+E+S D+
Sbjct: 125 EGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDE 184
Query: 216 ESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQN------SSKKESES 269
+ +E+ +K + + +S+K +K + + DS ++ +++ SS +SE
Sbjct: 185 DEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEE 244
Query: 270 EDSSDDEPLIKKLKKPPTDEELKETIKK 297
E+ + LKK PT +E K+ +K
Sbjct: 245 EEGKQTALASRFLKKAPTTDEDKKAAEK 272
Score = 47.8 bits (112), Expect = 1e-05
Identities = 50/199 (25%), Positives = 79/199 (39%), Gaps = 35/199 (17%)
Query: 116 KKFRNAMLKSICEVLDLERSGV---NSELVKRILNFLMHPKPSGKPLPKSKKTCSKGS-- 170
K+ + M K+ + L R + N + I ++ +P+ S + + S+GS
Sbjct: 124 KEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSD 183
Query: 171 ---------------KKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDK 215
KK SG +RK + K + D S++DE + +S D D
Sbjct: 184 EDEDEDGVSAATFLKKKSEAPSGESRKFLK-KMDDEDEDSEDSEDDEDWDTGSTSSDSDS 242
Query: 216 ESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKK--ESESEDSS 273
E EE A R K T + KK+ + KK + KK+ SK+ E E ED+
Sbjct: 243 EEEEGKQTALASRFLKKAPTTDEDKKAAE----KKREDKAKKKHDRKSKRLDEEEEEDNE 298
Query: 274 DDE--------PLIKKLKK 284
E PL+K+ K
Sbjct: 299 GGEWERVRGGVPLVKEKPK 317
Score = 32.0 bits (71), Expect = 0.82
Identities = 21/89 (23%), Positives = 39/89 (43%), Gaps = 9/89 (10%)
Query: 213 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDS 272
EDKE +++ K AK ++ K + +S + ++++ K E +SE S
Sbjct: 122 EDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGS 181
Query: 273 SDDE---------PLIKKLKKPPTDEELK 292
SD++ +KK + P+ E K
Sbjct: 182 SDEDEDEDGVSAATFLKKKSEAPSGESRK 210
>gi|195976782 Paf1/RNA polymerase II complex component [Homo
sapiens]
Length = 710
Score = 53.5 bits (127), Expect = 3e-07
Identities = 57/233 (24%), Positives = 97/233 (41%), Gaps = 27/233 (11%)
Query: 2 SASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEE-EKGKGQKLCEIE-- 58
+AS+ +++ + + A E+ S D D E+EE G G+ L E
Sbjct: 133 TASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEED 192
Query: 59 --RIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLK 116
R+ K++ EL +NR LK+ F +K KKKE+ K
Sbjct: 193 RARLEQMTEKEREQEL-------FNRIEKREVLKRR------FEIKKKLKTAKKKEKKEK 239
Query: 117 KFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNS 176
K + + ++ ++ S V S +R K K + + +K R +
Sbjct: 240 KKKQEEEQEKKKLTQIQESQVTSHNKER--RSKRDEKLDKKSQAMEELKAEREKRKNRTA 297
Query: 177 SGMARKAKRTKCPEILSDESSSDEDEKKNKEE------SSDDEDKESEEEPPK 223
+A+K + K E+ SD+ +ED+K +++ SS DE++E EE PPK
Sbjct: 298 ELLAKK-QPLKTSEVYSDDEEEEEDDKSSEKSDRSSRTSSSDEEEEKEEIPPK 349
Score = 45.1 bits (105), Expect = 9e-05
Identities = 58/287 (20%), Positives = 115/287 (40%), Gaps = 48/287 (16%)
Query: 18 ASEKEPEMPGPREESEEEEDEDDEE-----EEEEEKGKGQKLCEIERIHFFLSKKKTDEL 72
+ EKEP + P S+ E + D+E + ++KGK +K+ E
Sbjct: 79 SEEKEPPVSQPAASSDSETSDSDDEWTFGSNKNKKKGKARKI----------------EK 122
Query: 73 RNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQ---------------YKKKEEMLKK 117
+ K N+ + S K+ S P E+G V + EE
Sbjct: 123 KGTMKKQANKTASSGSSDKDSSAESSAP-EEGEVSDSDSNSSSSSSDSDSSSEDEEFHDG 181
Query: 118 FRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGK--PLPKSKKTCSKGSKKERN 175
+ ++ + LE+ E + + N + + + + K KT K KKE+
Sbjct: 182 YGEDLMGDEEDRARLEQM-TEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKK 240
Query: 176 SSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKA 235
+ K+ K +I + +S E+++K + D+ ++ EE + KR+ +
Sbjct: 241 KKQEEEQEKK-KLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAEL 299
Query: 236 TSKSKKSVKSANV------KKADSSTTKKNQNSSKKESESEDSSDDE 276
+K K+ +K++ V ++ D +++K+ SS+ S E+ +E
Sbjct: 300 LAK-KQPLKTSEVYSDDEEEEEDDKSSEKSDRSSRTSSSDEEEEKEE 345
Score = 44.3 bits (103), Expect = 2e-04
Identities = 35/168 (20%), Positives = 71/168 (42%), Gaps = 8/168 (4%)
Query: 170 SKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKRE 229
S +R S K P SD +SD D++ + + + ++ + K T K++
Sbjct: 70 SLAKRKRSDSEEKEPPVSQPAASSDSETSDSDDEWTFGSNKNKKKGKARKIEKKGTMKKQ 129
Query: 230 KPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDE 289
K ++ S K + + + + + NSS S+S+ SS+DE + +
Sbjct: 130 ANKTASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGD 189
Query: 290 ELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLTERKDFIKTTVK 337
E A LE++T K+ ++++ ++ +R+ IK +K
Sbjct: 190 EEDR--------ARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLK 229
Score = 39.3 bits (90), Expect = 0.005
Identities = 45/165 (27%), Positives = 69/165 (41%), Gaps = 30/165 (18%)
Query: 161 KSKKTCSKGSK-KERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEE---------SS 210
++ KT S GS K+ ++ A + + S SSSD D EE
Sbjct: 129 QANKTASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMG 188
Query: 211 DDED---------KESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQN 261
D+ED KE E+E + KRE K++ + KK +K+A K+ K+ +
Sbjct: 189 DEEDRARLEQMTEKEREQELFNRIEKREVLKRR--FEIKKKLKTAKKKEKKEKKKKQEEE 246
Query: 262 SSKKE----SESEDSSDDEPLIKKL-----KKPPTDEELKETIKK 297
KK+ ES+ +S ++ K KK EELK +K
Sbjct: 247 QEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREK 291
Score = 31.6 bits (70), Expect = 1.1
Identities = 39/201 (19%), Positives = 75/201 (37%), Gaps = 21/201 (10%)
Query: 153 KPSGKPLPKSKKTCSKGSKKERNSSGMARK--AKRTKCPEILSDESSSDEDEKKNKEESS 210
K GK KK K + SSG + K + + PE S + + S
Sbjct: 112 KKKGKARKIEKKGTMKKQANKTASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDSDS 171
Query: 211 DDEDKE-----------SEEEPPKKTAKREKPKQK----ATSKSKKSVKSANVKKADSST 255
ED+E EE+ + EK +++ K + + +KK +
Sbjct: 172 SSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTA 231
Query: 256 TKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQI-CK 314
KK + KK+ E E ++ + ++++ KE K + + M+++ +
Sbjct: 232 KKKEKKEKKKKQEEE---QEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAE 288
Query: 315 KVYENYPTYDLTERKDFIKTT 335
+ T +L +K +KT+
Sbjct: 289 REKRKNRTAELLAKKQPLKTS 309
>gi|83700233 eukaryotic translation initiation factor 3, subunit C
[Homo sapiens]
Length = 913
Score = 53.5 bits (127), Expect = 3e-07
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 18/148 (12%)
Query: 168 KGSKKERNSSGMARKAKRTKCPEILSD------------ESSSDEDEKKNKEESSDDEDK 215
+G KK ++ A R K + D E S+DED +KN+E+S D+
Sbjct: 125 EGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDE 184
Query: 216 ESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQN------SSKKESES 269
+ +E+ +K + + +S+K +K + + DS ++ +++ SS +SE
Sbjct: 185 DEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEE 244
Query: 270 EDSSDDEPLIKKLKKPPTDEELKETIKK 297
E+ + LKK PT +E K+ +K
Sbjct: 245 EEGKQTALASRFLKKAPTTDEDKKAAEK 272
Score = 48.1 bits (113), Expect = 1e-05
Identities = 48/197 (24%), Positives = 79/197 (40%), Gaps = 32/197 (16%)
Query: 116 KKFRNAMLKSICEVLDLERSGV---NSELVKRILNFLMHPKPSGKPLPKSKKTCSKGS-- 170
K+ + M K+ + L R + N + I ++ +P+ S + + S+GS
Sbjct: 124 KEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSD 183
Query: 171 ---------------KKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDK 215
KK SG +RK + K + D S++DE + +S D D
Sbjct: 184 EDEDEDGVSAATFLKKKSEAPSGESRKFLK-KMDDEDEDSEDSEDDEDWDTGSTSSDSDS 242
Query: 216 ESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDD 275
E EE A R K T + K K+A K+ D + K ++ S + + E ED+
Sbjct: 243 EEEEGKQTALASRFLKKAPTTDEDK---KAAEKKREDKAKKKHDRKSKRLDEEEEDNEGG 299
Query: 276 E--------PLIKKLKK 284
E PL+K+ K
Sbjct: 300 EWERVRGGVPLVKEKPK 316
Score = 32.0 bits (71), Expect = 0.82
Identities = 21/89 (23%), Positives = 39/89 (43%), Gaps = 9/89 (10%)
Query: 213 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDS 272
EDKE +++ K AK ++ K + +S + ++++ K E +SE S
Sbjct: 122 EDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGS 181
Query: 273 SDDE---------PLIKKLKKPPTDEELK 292
SD++ +KK + P+ E K
Sbjct: 182 SDEDEDEDGVSAATFLKKKSEAPSGESRK 210
>gi|4503525 eukaryotic translation initiation factor 3, subunit C
[Homo sapiens]
Length = 913
Score = 53.5 bits (127), Expect = 3e-07
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 18/148 (12%)
Query: 168 KGSKKERNSSGMARKAKRTKCPEILSD------------ESSSDEDEKKNKEESSDDEDK 215
+G KK ++ A R K + D E S+DED +KN+E+S D+
Sbjct: 125 EGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDE 184
Query: 216 ESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQN------SSKKESES 269
+ +E+ +K + + +S+K +K + + DS ++ +++ SS +SE
Sbjct: 185 DEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEE 244
Query: 270 EDSSDDEPLIKKLKKPPTDEELKETIKK 297
E+ + LKK PT +E K+ +K
Sbjct: 245 EEGKQTALASRFLKKAPTTDEDKKAAEK 272
Score = 48.1 bits (113), Expect = 1e-05
Identities = 48/197 (24%), Positives = 79/197 (40%), Gaps = 32/197 (16%)
Query: 116 KKFRNAMLKSICEVLDLERSGV---NSELVKRILNFLMHPKPSGKPLPKSKKTCSKGS-- 170
K+ + M K+ + L R + N + I ++ +P+ S + + S+GS
Sbjct: 124 KEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSD 183
Query: 171 ---------------KKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDK 215
KK SG +RK + K + D S++DE + +S D D
Sbjct: 184 EDEDEDGVSAATFLKKKSEAPSGESRKFLK-KMDDEDEDSEDSEDDEDWDTGSTSSDSDS 242
Query: 216 ESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDD 275
E EE A R K T + K K+A K+ D + K ++ S + + E ED+
Sbjct: 243 EEEEGKQTALASRFLKKAPTTDEDK---KAAEKKREDKAKKKHDRKSKRLDEEEEDNEGG 299
Query: 276 E--------PLIKKLKK 284
E PL+K+ K
Sbjct: 300 EWERVRGGVPLVKEKPK 316
Score = 32.0 bits (71), Expect = 0.82
Identities = 21/89 (23%), Positives = 39/89 (43%), Gaps = 9/89 (10%)
Query: 213 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDS 272
EDKE +++ K AK ++ K + +S + ++++ K E +SE S
Sbjct: 122 EDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGS 181
Query: 273 SDDE---------PLIKKLKKPPTDEELK 292
SD++ +KK + P+ E K
Sbjct: 182 SDEDEDEDGVSAATFLKKKSEAPSGESRK 210
>gi|122937227 U2-associated SR140 protein [Homo sapiens]
Length = 1029
Score = 53.1 bits (126), Expect = 3e-07
Identities = 61/269 (22%), Positives = 117/269 (43%), Gaps = 33/269 (12%)
Query: 16 QPASEKEPEMPGPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDELR-- 73
Q + + E+ EESEEEE+++ EEE E+E+ E ++ K++ E +
Sbjct: 772 QAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFS 831
Query: 74 NLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKK-----EEMLKKFRNAMLKSICE 128
++ + + ++ V +F E S + KK +E ++ +R+ +L+ E
Sbjct: 832 KYSEMSEEKRAKLREIELKVMKFQD---ELESGKRPKKPGQSFQEQVEHYRDKLLQREKE 888
Query: 129 VLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSG----MARKAK 184
+LER + K L K K + T ++ +K R+S+ + +
Sbjct: 889 K-ELERERERDKKDKEKLESRSKDKKE-----KDECTPTRKERKRRHSTSPSPSRSSSGR 942
Query: 185 RTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREK--------PKQKAT 236
R K P S+ S + E+ +KE S + S ++ P+ +K+ K PK+
Sbjct: 943 RVKSPSPKSERS--ERSERSHKESS---RSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRR 997
Query: 237 SKSKKSVKSANVKKADSSTTKKNQNSSKK 265
S+S+ KS ++ S + ++ SKK
Sbjct: 998 SRSRSPKKSGKKSRSQSRSPHRSHKKSKK 1026
Score = 32.0 bits (71), Expect = 0.82
Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 6/89 (6%)
Query: 175 NSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDED-----KESEEEPPKKTAKRE 229
+ S + +A T E+ S+E+E +N+EE S+DE+ K E K E
Sbjct: 765 DESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEE 824
Query: 230 KPKQKATSKSKKS-VKSANVKKADSSTTK 257
+ K + S+ S K A +++ + K
Sbjct: 825 MTESKFSKYSEMSEEKRAKLREIELKVMK 853
Score = 29.6 bits (65), Expect = 4.1
Identities = 42/174 (24%), Positives = 67/174 (38%), Gaps = 55/174 (31%)
Query: 161 KSKKTCSKGSKKERNSSGMARKAKRTKCPEI------LSDESSSDEDEKKNKEESSDDED 214
K + T SK SK S + KR K EI DE S + KK + + +
Sbjct: 822 KEEMTESKFSKYSEMS-----EEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVE 876
Query: 215 --------KESEEEPPKKTAKREKPKQKATSKSK-------------------------- 240
+E E+E ++ + +K K+K S+SK
Sbjct: 877 HYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPS 936
Query: 241 -----KSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEP--LIKKLKKPPT 287
+ VKS + K S +++++ S K+ S S S D P + KK K+ P+
Sbjct: 937 RSSSGRRVKSPSPK---SERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPS 987
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.300 0.121 0.317
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,118,321
Number of Sequences: 37866
Number of extensions: 853261
Number of successful extensions: 39989
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1157
Number of HSP's successfully gapped in prelim test: 1045
Number of HSP's that attempted gapping in prelim test: 9992
Number of HSP's gapped (non-prelim): 17000
length of query: 341
length of database: 18,247,518
effective HSP length: 103
effective length of query: 238
effective length of database: 14,347,320
effective search space: 3414662160
effective search space used: 3414662160
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.