Guide to the Human Genome
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Search of human proteins with 197313705

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|197313705 5-azacytidine induced 2 isoform b [Homo sapiens]
         (243 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|197313705 5-azacytidine induced 2 isoform b [Homo sapiens]         481   e-136
gi|197313707 5-azacytidine induced 2 isoform c [Homo sapiens]         426   e-120
gi|11968003 5-azacytidine induced 2 isoform a [Homo sapiens]          424   e-119
gi|7662302 TBK1 binding protein 1 [Homo sapiens]                       61   8e-10
gi|34878904 synaptonemal complex protein 1 [Homo sapiens]              55   7e-08
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    54   1e-07
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    54   1e-07
gi|237858621 polyamine modulated factor 1 binding protein 1 isof...    50   2e-06
gi|237858619 polyamine modulated factor 1 binding protein 1 isof...    50   2e-06
gi|224451082 cytospin A [Homo sapiens]                                 49   3e-06
gi|224451080 cytospin A [Homo sapiens]                                 49   3e-06
gi|190194355 p90 autoantigen [Homo sapiens]                            47   2e-05
gi|153945715 myosin VC [Homo sapiens]                                  46   3e-05
gi|38044112 restin isoform b [Homo sapiens]                            45   4e-05
gi|4506751 restin isoform a [Homo sapiens]                             45   4e-05
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap...    45   7e-05
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]    45   7e-05
gi|18390344 ATR interacting protein isoform 2 [Homo sapiens]           44   1e-04
gi|18390347 ATR interacting protein isoform 1 [Homo sapiens]           44   1e-04
gi|110815815 centlein isoform 1 [Homo sapiens]                         44   2e-04
gi|167555106 centlein isoform 2 [Homo sapiens]                         44   2e-04
gi|55956899 keratin 9 [Homo sapiens]                                   43   2e-04
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]                   43   2e-04
gi|19743571 TRAF interacting protein TANK isoform b [Homo sapiens]     43   3e-04
gi|19743569 TRAF interacting protein TANK isoform a [Homo sapiens]     43   3e-04
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]         43   3e-04
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]         43   3e-04
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]         43   3e-04
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]         43   3e-04
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]         43   3e-04

>gi|197313705 5-azacytidine induced 2 isoform b [Homo sapiens]
          Length = 243

 Score =  481 bits (1237), Expect = e-136
 Identities = 243/243 (100%), Positives = 243/243 (100%)

Query: 1   MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 60
           MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS
Sbjct: 1   MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 60

Query: 61  LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 120
           LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES
Sbjct: 61  LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 120

Query: 121 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 180
           LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR
Sbjct: 121 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 180

Query: 181 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRQSICSTAWSAVAQSWDSMNFEDCS 240
           KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRQSICSTAWSAVAQSWDSMNFEDCS
Sbjct: 181 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRQSICSTAWSAVAQSWDSMNFEDCS 240

Query: 241 LFA 243
           LFA
Sbjct: 241 LFA 243


>gi|197313707 5-azacytidine induced 2 isoform c [Homo sapiens]
          Length = 232

 Score =  426 bits (1095), Expect = e-120
 Identities = 217/219 (99%), Positives = 218/219 (99%)

Query: 1   MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 60
           MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS
Sbjct: 1   MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 60

Query: 61  LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 120
           LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES
Sbjct: 61  LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 120

Query: 121 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 180
           LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR
Sbjct: 121 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 180

Query: 181 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRQSI 219
           KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISR S+
Sbjct: 181 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRVSV 219


>gi|11968003 5-azacytidine induced 2 isoform a [Homo sapiens]
          Length = 392

 Score =  424 bits (1091), Expect = e-119
 Identities = 216/224 (96%), Positives = 218/224 (97%)

Query: 1   MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 60
           MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS
Sbjct: 1   MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 60

Query: 61  LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 120
           LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES
Sbjct: 61  LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 120

Query: 121 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 180
           LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR
Sbjct: 121 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 180

Query: 181 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRQSICSTAW 224
           KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSIS  ++    W
Sbjct: 181 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYW 224


>gi|7662302 TBK1 binding protein 1 [Homo sapiens]
          Length = 615

 Score = 61.2 bits (147), Expect = 8e-10
 Identities = 51/156 (32%), Positives = 80/156 (51%), Gaps = 10/156 (6%)

Query: 1   MDALVEDDICILNHEKAHKR----DTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSE 56
           M+++ EDDI IL  E         D+    S+  GD   ASHFAL+TAY DIK+RL   E
Sbjct: 1   MESMFEDDISILTQEALGPSEVWLDSPGDPSL-GGDMCSASHFALITAYGDIKERLGGLE 59

Query: 57  KENSLLKKRIRFLEEK--LIARFEEETSSVGREQVNKAYHAYREVCIDR--DNLKSKLDK 112
           +EN+ L++R++  E K  LI+ F EE      E  + +     +V + +  +  + +L K
Sbjct: 60  RENATLRRRLKVYEIKYPLISDFGEEHGFSLYEIKDGSLLEVEKVSLQQRLNQFQHELQK 119

Query: 113 MNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVM 148
            NK+  E L  + +  +   VE   L TE+   + +
Sbjct: 120 -NKEQEEQLGEMIQAYEKLCVEKSDLETELREMRAL 154


>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
          Length = 976

 Score = 54.7 bits (130), Expect = 7e-08
 Identities = 53/214 (24%), Positives = 100/214 (46%), Gaps = 26/214 (12%)

Query: 13  NHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLLKKRIRFLEEK 72
           + +K ++ +  T +   +  +S+     L    EDIK  L+ S      L++ ++   + 
Sbjct: 292 SRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKT 351

Query: 73  LIARFEEETSSVGREQVNKAYHAY--------REVCIDRDNLKSKLDKMNKDNSESLKVL 124
           +    EE+ + +  E+ NKA  A+          VC   + L+++  ++ K N + LK+L
Sbjct: 352 ICQLTEEKETQM--EESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEK-NEDQLKIL 408

Query: 125 NEQLQSKEVELLQL-----RTEVETQQVMRNLNPPSS----NWEVEKLSCDLKIHGLEQE 175
             +LQ K  EL ++       EVE +++ + L    +    N + EK++ +LK  G EQE
Sbjct: 409 TMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELK--GTEQE 466

Query: 176 ----LELMRKECSDLKIELQKAKQTDPYQEDNLK 205
               L+   KE  DL+I+L     ++ Y    +K
Sbjct: 467 LIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVK 500



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 48/180 (26%), Positives = 73/180 (40%), Gaps = 30/180 (16%)

Query: 38  HFALVTAYEDI-------KKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVN 90
           HF L   YE I       KK + D EK+ SLL  +I   E K+     ++ + +  E  +
Sbjct: 240 HFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKM-----KDLTFLLEESRD 294

Query: 91  KAYHAYREVCIDRDNLKSKLDKMNKDNSE-------------SLKVLNEQLQSKEVELLQ 137
           K      +  +  +NLK  ++K +    E             + K L E LQ     + Q
Sbjct: 295 KVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQ 354

Query: 138 LRTEVETQQVMRNLNPPSSNW---EVEKLSCDLK--IHGLEQELELMRKECSDLKIELQK 192
           L  E ETQ    N    + ++   E E   C L+  +   +Q LE    +   L +ELQK
Sbjct: 355 LTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQK 414



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 39/160 (24%), Positives = 78/160 (48%), Gaps = 19/160 (11%)

Query: 47  DIKKRLKDSEKENSLLKKRIRFLEEKLIARFE--EETSSVGREQVNKAYHAYREVCIDRD 104
           D+   LK+ +++ +  KK+    EE+++ + E  +ET +  R   N+  +   E+   RD
Sbjct: 536 DMTLELKNQQEDINNNKKQ----EERMLKQIENLQETETQLR---NELEYVREELKQKRD 588

Query: 105 NLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLS 164
            +K KLDK    + E+   L +Q+++K   + +L      QQ  + L    +    +   
Sbjct: 589 EVKCKLDK----SEENCNNLRKQVENKNKYIEEL------QQENKALKKKGTAESKQLNV 638

Query: 165 CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNL 204
            ++K++ LE ELE  +++  ++    QK  +     E+NL
Sbjct: 639 YEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENL 678



 Score = 29.6 bits (65), Expect = 2.5
 Identities = 39/170 (22%), Positives = 74/170 (43%), Gaps = 27/170 (15%)

Query: 33  ESVASHFALVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKA 92
           ES    F  +T  +  +K ++D +     L + +   + K+IA   +E   + +E   + 
Sbjct: 651 ESAKQKFGEIT--DTYQKEIEDKKISEENLLEEVE--KAKVIA---DEAVKLQKEIDKRC 703

Query: 93  YHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLN 152
            H   E+    +  K + DK+ ++    L +     +SKE E   LR  +E +       
Sbjct: 704 QHKIAEMVALMEKHKHQYDKIIEERDSELGLY----KSKEQEQSSLRASLEIEL------ 753

Query: 153 PPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQED 202
              SN + E LS       ++++LE+ R+E   LK E ++   T   ++D
Sbjct: 754 ---SNLKAELLS-------VKKQLEIEREEKEKLKREAKENTATLKEKKD 793


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 51/189 (26%), Positives = 97/189 (51%), Gaps = 21/189 (11%)

Query: 46  EDIKKRLKDSEKENSLLKKRIRFLE---EKLIARFEEETSSVGRE--QVNKAYHAYREVC 100
           E+++  L   EKEN LL+K+I  L+   EK+ A  E+E S + RE  ++ K   +++ + 
Sbjct: 628 EELENELHHLEKENELLQKKITNLKITCEKIEA-LEQENSELERENRKLKKTLDSFKNLT 686

Query: 101 IDRDNLK---SKLDKMNKD---NSESLKVLNEQLQSKEVELLQLRTEVETQ----QVMRN 150
              ++L+   S+LD+ N +   N ESLK  + ++   ++E  +L +E E      ++++ 
Sbjct: 687 FQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKA 746

Query: 151 LNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQ 210
               +   EV     D++   L++ LE   K+   L+ ELQ     D   E+    ++L+
Sbjct: 747 SFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ-----DLEMENQTLQKNLE 801

Query: 211 KLSISRQSI 219
           +L IS + +
Sbjct: 802 ELKISSKRL 810



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 59/227 (25%), Positives = 99/227 (43%), Gaps = 42/227 (18%)

Query: 6   EDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLLKKR 65
           E  I IL  E  H   TV+ +   S   + A              R+KD EKEN +L + 
Sbjct: 550 ERQIKILEQENEHLNQTVSSLRQRSQISAEA--------------RVKDIEKENKILHES 595

Query: 66  IRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNS------E 119
           I+    KL ++ E E     + Q+ K    Y+E     + L+++L  + K+N        
Sbjct: 596 IKETSSKL-SKIEFE-----KRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKIT 649

Query: 120 SLKVLNEQLQSKEVELLQLRTE----VETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQE 175
           +LK+  E++++ E E  +L  E     +T    +NL     + E E    D      E+ 
Sbjct: 650 NLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLD------EEN 703

Query: 176 LELMRK----ECSDLKI-ELQ-KAKQTDPYQEDNLKSRDLQKLSISR 216
           LEL R     +C+ +K+ +LQ + K+ +  +E   K  +L K S  +
Sbjct: 704 LELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKK 750



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 47/164 (28%), Positives = 80/164 (48%), Gaps = 21/164 (12%)

Query: 53  KDSEKENSLLKKRIRFLEE---KLIARFEEETSSVGREQVNKAYHAYREVC-IDRDNLKS 108
           KD  KE + L+K I  L E   + I   E+E      E +N+   + R+   I  +    
Sbjct: 529 KDLMKEKAQLEKTIETLRENSERQIKILEQEN-----EHLNQTVSSLRQRSQISAEARVK 583

Query: 109 KLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLK 168
            ++K NK   ES+K  + +L   E E  Q++ E+E  +              E+L  +L 
Sbjct: 584 DIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYK--------EKGERAEELENEL- 634

Query: 169 IHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKL 212
            H LE+E EL++K+ ++LKI  +K +  +  QE++   R+ +KL
Sbjct: 635 -HHLEKENELLQKKITNLKITCEKIEALE--QENSELERENRKL 675



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 41/182 (22%), Positives = 83/182 (45%), Gaps = 8/182 (4%)

Query: 46  EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSS-VGREQVNKAYHAYREVCIDRD 104
           E+  ++L D ++E   ++  ++ L+++ +    +  S+ + R++++    A RE  +  D
Sbjct: 268 EEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELD----ALREKAVRVD 323

Query: 105 NLKSKLDKMNK--DNSESLKVLNEQLQSKEVELLQLRTEVETQ-QVMRNLNPPSSNWEVE 161
            L+S++ +  +   + E  K   E+L+     LL+ +T +E Q +  R  +      E E
Sbjct: 324 KLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE 383

Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRQSICS 221
            L    K+H +E E ++ RK+  +L  E    +       D       +   ISR S  S
Sbjct: 384 NLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELS 443

Query: 222 TA 223
            A
Sbjct: 444 EA 445



 Score = 36.2 bits (82), Expect = 0.027
 Identities = 41/179 (22%), Positives = 86/179 (48%), Gaps = 28/179 (15%)

Query: 46  EDIKKRLKDSEKENSLLKKRIRFLE--EKLIARFEEETSSVGREQVNKAYHAYREVCIDR 103
           + ++  L+D E EN  L+K +  L+   K + + E+E  S+ +E             +++
Sbjct: 780 QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQ----------LEK 829

Query: 104 DNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKL 163
           D  K +L+K NK   +  ++ +  L+   V++  L  E +T          S    + K 
Sbjct: 830 D--KKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTL---------SKEIGIYKE 878

Query: 164 SCDLKIHGLEQE-LELMRKECSDLK--IELQKAKQTDPYQEDNLKSRDLQKLSISRQSI 219
           SC +++  LE+E  EL+++   D+K  + L++   ++  +   + + DL+KL+   + I
Sbjct: 879 SC-VRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQM-NNDLEKLTHELEKI 935



 Score = 36.2 bits (82), Expect = 0.027
 Identities = 49/216 (22%), Positives = 84/216 (38%), Gaps = 41/216 (18%)

Query: 45   YEDIKKRLKDSEKENSLLKKRIRF-------LEEKLIAR----------FEEETSSVGRE 87
            Y++   RLK+ EKEN  L KR          L E L++            E+ T  + + 
Sbjct: 876  YKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 935

Query: 88   QVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVEL-------LQLRT 140
             +NK    + E   D    K    K+     +SL++  E++ + E  L        QLR 
Sbjct: 936  GLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQ 995

Query: 141  EVET-------------QQVMRNLNPPSS----NWEVEKLSCDLKIHGLEQELELMRKEC 183
            E++T             ++ M   +PP S     WE E      ++  ++  L  + +  
Sbjct: 996  ELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNN 1055

Query: 184  SDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRQSI 219
            + L+ E Q  K      E    +   Q L++ RQ++
Sbjct: 1056 ATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTV 1091



 Score = 36.2 bits (82), Expect = 0.027
 Identities = 46/208 (22%), Positives = 92/208 (44%), Gaps = 16/208 (7%)

Query: 8    DICILNHEKA---HKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSE-KENSLLK 63
            D  I +HEK    H+R      S+      ++ H  L +A+++++   +D E + N LLK
Sbjct: 1154 DSLIKDHEKLELLHERQASEYESL------ISKHGTLKSAHKNLEVEHRDLEDRYNQLLK 1207

Query: 64   KRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKV 123
            ++ +  + + + + E+E   +  +        Y+++C + D L     ++ K+ +E L+ 
Sbjct: 1208 QKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE-TEVLQT 1266

Query: 124  LNEQLQS--KEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRK 181
             ++ L+S     +L Q R E E  ++                 C+L +  L+  LE   +
Sbjct: 1267 DHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCEL-LSQLKGNLEEENR 1325

Query: 182  ECSDLKIELQKAKQTDPYQEDNLKSRDL 209
               D    L    +T    E N++S+DL
Sbjct: 1326 HLLDQIQTLMLQNRT--LLEQNMESKDL 1351


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 51/189 (26%), Positives = 97/189 (51%), Gaps = 21/189 (11%)

Query: 46  EDIKKRLKDSEKENSLLKKRIRFLE---EKLIARFEEETSSVGRE--QVNKAYHAYREVC 100
           E+++  L   EKEN LL+K+I  L+   EK+ A  E+E S + RE  ++ K   +++ + 
Sbjct: 628 EELENELHHLEKENELLQKKITNLKITCEKIEA-LEQENSELERENRKLKKTLDSFKNLT 686

Query: 101 IDRDNLK---SKLDKMNKD---NSESLKVLNEQLQSKEVELLQLRTEVETQ----QVMRN 150
              ++L+   S+LD+ N +   N ESLK  + ++   ++E  +L +E E      ++++ 
Sbjct: 687 FQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKA 746

Query: 151 LNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQ 210
               +   EV     D++   L++ LE   K+   L+ ELQ     D   E+    ++L+
Sbjct: 747 SFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ-----DLEMENQTLQKNLE 801

Query: 211 KLSISRQSI 219
           +L IS + +
Sbjct: 802 ELKISSKRL 810



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 59/227 (25%), Positives = 99/227 (43%), Gaps = 42/227 (18%)

Query: 6   EDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLLKKR 65
           E  I IL  E  H   TV+ +   S   + A              R+KD EKEN +L + 
Sbjct: 550 ERQIKILEQENEHLNQTVSSLRQRSQISAEA--------------RVKDIEKENKILHES 595

Query: 66  IRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNS------E 119
           I+    KL ++ E E     + Q+ K    Y+E     + L+++L  + K+N        
Sbjct: 596 IKETSSKL-SKIEFE-----KRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKIT 649

Query: 120 SLKVLNEQLQSKEVELLQLRTE----VETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQE 175
           +LK+  E++++ E E  +L  E     +T    +NL     + E E    D      E+ 
Sbjct: 650 NLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLD------EEN 703

Query: 176 LELMRK----ECSDLKI-ELQ-KAKQTDPYQEDNLKSRDLQKLSISR 216
           LEL R     +C+ +K+ +LQ + K+ +  +E   K  +L K S  +
Sbjct: 704 LELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKK 750



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 47/164 (28%), Positives = 80/164 (48%), Gaps = 21/164 (12%)

Query: 53  KDSEKENSLLKKRIRFLEE---KLIARFEEETSSVGREQVNKAYHAYREVC-IDRDNLKS 108
           KD  KE + L+K I  L E   + I   E+E      E +N+   + R+   I  +    
Sbjct: 529 KDLMKEKAQLEKTIETLRENSERQIKILEQEN-----EHLNQTVSSLRQRSQISAEARVK 583

Query: 109 KLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLK 168
            ++K NK   ES+K  + +L   E E  Q++ E+E  +              E+L  +L 
Sbjct: 584 DIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYK--------EKGERAEELENEL- 634

Query: 169 IHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKL 212
            H LE+E EL++K+ ++LKI  +K +  +  QE++   R+ +KL
Sbjct: 635 -HHLEKENELLQKKITNLKITCEKIEALE--QENSELERENRKL 675



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 41/182 (22%), Positives = 83/182 (45%), Gaps = 8/182 (4%)

Query: 46  EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSS-VGREQVNKAYHAYREVCIDRD 104
           E+  ++L D ++E   ++  ++ L+++ +    +  S+ + R++++    A RE  +  D
Sbjct: 268 EEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELD----ALREKAVRVD 323

Query: 105 NLKSKLDKMNK--DNSESLKVLNEQLQSKEVELLQLRTEVETQ-QVMRNLNPPSSNWEVE 161
            L+S++ +  +   + E  K   E+L+     LL+ +T +E Q +  R  +      E E
Sbjct: 324 KLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE 383

Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRQSICS 221
            L    K+H +E E ++ RK+  +L  E    +       D       +   ISR S  S
Sbjct: 384 NLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELS 443

Query: 222 TA 223
            A
Sbjct: 444 EA 445



 Score = 36.2 bits (82), Expect = 0.027
 Identities = 41/179 (22%), Positives = 86/179 (48%), Gaps = 28/179 (15%)

Query: 46  EDIKKRLKDSEKENSLLKKRIRFLE--EKLIARFEEETSSVGREQVNKAYHAYREVCIDR 103
           + ++  L+D E EN  L+K +  L+   K + + E+E  S+ +E             +++
Sbjct: 780 QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQ----------LEK 829

Query: 104 DNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKL 163
           D  K +L+K NK   +  ++ +  L+   V++  L  E +T          S    + K 
Sbjct: 830 D--KKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTL---------SKEIGIYKE 878

Query: 164 SCDLKIHGLEQE-LELMRKECSDLK--IELQKAKQTDPYQEDNLKSRDLQKLSISRQSI 219
           SC +++  LE+E  EL+++   D+K  + L++   ++  +   + + DL+KL+   + I
Sbjct: 879 SC-VRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQM-NNDLEKLTHELEKI 935



 Score = 36.2 bits (82), Expect = 0.027
 Identities = 46/208 (22%), Positives = 92/208 (44%), Gaps = 16/208 (7%)

Query: 8    DICILNHEKA---HKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSE-KENSLLK 63
            D  I +HEK    H+R      S+      ++ H  L +A+++++   +D E + N LLK
Sbjct: 1153 DSLIKDHEKLELLHERQASEYESL------ISKHGTLKSAHKNLEVEHRDLEDRYNQLLK 1206

Query: 64   KRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKV 123
            ++ +  + + + + E+E   +  +        Y+++C + D L     ++ K+ +E L+ 
Sbjct: 1207 QKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE-TEVLQT 1265

Query: 124  LNEQLQS--KEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRK 181
             ++ L+S     +L Q R E E  ++                 C+L +  L+  LE   +
Sbjct: 1266 DHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCEL-LSQLKGNLEEENR 1324

Query: 182  ECSDLKIELQKAKQTDPYQEDNLKSRDL 209
               D    L    +T    E N++S+DL
Sbjct: 1325 HLLDQIQTLMLQNRT--LLEQNMESKDL 1350



 Score = 35.0 bits (79), Expect = 0.059
 Identities = 47/215 (21%), Positives = 86/215 (40%), Gaps = 40/215 (18%)

Query: 45   YEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQ-----VNKAYHAYREV 99
            Y++   RLK+ EKEN  L KR     + L+   E+  S   + Q     + K  H   ++
Sbjct: 876  YKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 935

Query: 100  CIDRDNL-----------KSKLDKMNKDNSESLKVLNEQLQSKEVEL-------LQLRTE 141
             ++++ L           K    K+     +SL++  E++ + E  L        QLR E
Sbjct: 936  GLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQE 995

Query: 142  VET-------------QQVMRNLNPPSS----NWEVEKLSCDLKIHGLEQELELMRKECS 184
            ++T             ++ M   +PP S     WE E      ++  ++  L  + +  +
Sbjct: 996  LKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNA 1055

Query: 185  DLKIELQKAKQTDPYQEDNLKSRDLQKLSISRQSI 219
             L+ E Q  K      E    +   Q L++ RQ++
Sbjct: 1056 TLQAEKQALKTQLKQLETQNNNLQAQILALQRQTV 1090


>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
           b [Homo sapiens]
          Length = 882

 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 45/191 (23%), Positives = 88/191 (46%), Gaps = 12/191 (6%)

Query: 45  YEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAY-REVCIDR 103
           Y   ++ ++D  KE +L K+ +  L+ +L    ++E   +      +AY A  R+    +
Sbjct: 538 YNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQ 597

Query: 104 DNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTE-VETQQVMRNLNPPSSNWEVEK 162
           D+L   L+K+N   SE+ K L + L   + +  QL  E +  ++ M+ LN          
Sbjct: 598 DDLTQALEKLNHVTSET-KSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFH 656

Query: 163 LSCDLKIHGLEQELELM--------RKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSI 214
              +L++H  +++LE M        ++  +DLK+   K +Q   +QE+    ++   L  
Sbjct: 657 QESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEEMAALKE-NLLED 715

Query: 215 SRQSICSTAWS 225
            ++  C   WS
Sbjct: 716 DKEPCCLPQWS 726



 Score = 34.7 bits (78), Expect = 0.077
 Identities = 46/200 (23%), Positives = 89/200 (44%), Gaps = 28/200 (14%)

Query: 47  DIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVG--REQVNKAYHAYREVCIDRD 104
           D+  R+K   +E   +K +   LEE L    +E T  +   REQ+ K+    + +  + +
Sbjct: 441 DMLDRIKHQHREQGSIKCK---LEEDL----QEATKLLEDKREQLKKSKEHEKLMEGELE 493

Query: 105 NLKS---KLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVE 161
            L+    K DK  K+NS  L+  NE L++   EL    T++E+     +LN  +++ +V 
Sbjct: 494 ALRQEFKKKDKTLKENSRKLEEENENLRA---ELQCCSTQLES-----SLNKYNTSQQV- 544

Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRQSICS 221
                  I  L +E+ L ++    L+ +L KA Q + +      +++       + + C 
Sbjct: 545 -------IQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQ 597

Query: 222 TAWSAVAQSWDSMNFEDCSL 241
              +   +  + +  E  SL
Sbjct: 598 DDLTQALEKLNHVTSETKSL 617



 Score = 33.1 bits (74), Expect = 0.22
 Identities = 42/167 (25%), Positives = 77/167 (46%), Gaps = 20/167 (11%)

Query: 42  VTAYEDIKKRLKD-----SEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAY 96
           V  Y+++ K L+      SE++ +++K  ++ LE  L    EE ++ + R+  +      
Sbjct: 177 VEEYQNLVKDLRVELEAVSEQKRNIMKDMMK-LELDLHGLREETSAHIERKDKDITILQC 235

Query: 97  R--EVCID---RDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNL 151
           R  E+ ++      L  K DK  ++  E L+ L ++L   +  LL+   E+E QQ M   
Sbjct: 236 RLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMAT- 294

Query: 152 NPPSSNWEVEKLSCDLK-IHGLEQELELMRKECSDLKIELQKAKQTD 197
                  E+E    + K     E E + ++ E   LK  L++AKQ +
Sbjct: 295 -------ELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQE 334



 Score = 27.7 bits (60), Expect = 9.4
 Identities = 34/161 (21%), Positives = 73/161 (45%), Gaps = 22/161 (13%)

Query: 46  EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDN 105
           ED +++L+     +      I+ L+ +L    ++E+S   +EQ +               
Sbjct: 356 EDTQRKLQKGLLLDKQKADTIQELQREL-QMLQKESSMAEKEQTSN-------------- 400

Query: 106 LKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSC 165
            + ++++++ + SE+L+ L      KE   LQ +T  E    M ++     +   E+ S 
Sbjct: 401 -RKRVEELSLELSEALRKLENS--DKEKRQLQ-KTVAEQDMKMNDMLDRIKHQHREQGSI 456

Query: 166 DLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKS 206
             K   LE++L+   K   D + +L+K+K+ +   E  L++
Sbjct: 457 KCK---LEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEA 494


>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
           a [Homo sapiens]
          Length = 1007

 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 45/191 (23%), Positives = 88/191 (46%), Gaps = 12/191 (6%)

Query: 45  YEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAY-REVCIDR 103
           Y   ++ ++D  KE +L K+ +  L+ +L    ++E   +      +AY A  R+    +
Sbjct: 683 YNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQ 742

Query: 104 DNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTE-VETQQVMRNLNPPSSNWEVEK 162
           D+L   L+K+N   SE+ K L + L   + +  QL  E +  ++ M+ LN          
Sbjct: 743 DDLTQALEKLNHVTSET-KSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFH 801

Query: 163 LSCDLKIHGLEQELELM--------RKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSI 214
              +L++H  +++LE M        ++  +DLK+   K +Q   +QE+    ++   L  
Sbjct: 802 QESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEEMAALKE-NLLED 860

Query: 215 SRQSICSTAWS 225
            ++  C   WS
Sbjct: 861 DKEPCCLPQWS 871



 Score = 34.7 bits (78), Expect = 0.077
 Identities = 46/200 (23%), Positives = 89/200 (44%), Gaps = 28/200 (14%)

Query: 47  DIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVG--REQVNKAYHAYREVCIDRD 104
           D+  R+K   +E   +K +   LEE L    +E T  +   REQ+ K+    + +  + +
Sbjct: 586 DMLDRIKHQHREQGSIKCK---LEEDL----QEATKLLEDKREQLKKSKEHEKLMEGELE 638

Query: 105 NLKS---KLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVE 161
            L+    K DK  K+NS  L+  NE L++   EL    T++E+     +LN  +++ +V 
Sbjct: 639 ALRQEFKKKDKTLKENSRKLEEENENLRA---ELQCCSTQLES-----SLNKYNTSQQV- 689

Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRQSICS 221
                  I  L +E+ L ++    L+ +L KA Q + +      +++       + + C 
Sbjct: 690 -------IQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQ 742

Query: 222 TAWSAVAQSWDSMNFEDCSL 241
              +   +  + +  E  SL
Sbjct: 743 DDLTQALEKLNHVTSETKSL 762



 Score = 33.1 bits (74), Expect = 0.22
 Identities = 42/167 (25%), Positives = 77/167 (46%), Gaps = 20/167 (11%)

Query: 42  VTAYEDIKKRLKD-----SEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAY 96
           V  Y+++ K L+      SE++ +++K  ++ LE  L    EE ++ + R+  +      
Sbjct: 322 VEEYQNLVKDLRVELEAVSEQKRNIMKDMMK-LELDLHGLREETSAHIERKDKDITILQC 380

Query: 97  R--EVCID---RDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNL 151
           R  E+ ++      L  K DK  ++  E L+ L ++L   +  LL+   E+E QQ M   
Sbjct: 381 RLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMAT- 439

Query: 152 NPPSSNWEVEKLSCDLK-IHGLEQELELMRKECSDLKIELQKAKQTD 197
                  E+E    + K     E E + ++ E   LK  L++AKQ +
Sbjct: 440 -------ELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQE 479



 Score = 27.7 bits (60), Expect = 9.4
 Identities = 34/161 (21%), Positives = 73/161 (45%), Gaps = 22/161 (13%)

Query: 46  EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDN 105
           ED +++L+     +      I+ L+ +L    ++E+S   +EQ +               
Sbjct: 501 EDTQRKLQKGLLLDKQKADTIQELQREL-QMLQKESSMAEKEQTSN-------------- 545

Query: 106 LKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSC 165
            + ++++++ + SE+L+ L      KE   LQ +T  E    M ++     +   E+ S 
Sbjct: 546 -RKRVEELSLELSEALRKLENS--DKEKRQLQ-KTVAEQDMKMNDMLDRIKHQHREQGSI 601

Query: 166 DLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKS 206
             K   LE++L+   K   D + +L+K+K+ +   E  L++
Sbjct: 602 KCK---LEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEA 639


>gi|224451082 cytospin A [Homo sapiens]
          Length = 1117

 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 44/185 (23%), Positives = 85/185 (45%), Gaps = 13/185 (7%)

Query: 46  EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYRE----VCI 101
           E+ KK+++D    N  L+K    L+EK   R + + +    E   + + A +     +  
Sbjct: 656 EEAKKQIEDL---NMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIIS 712

Query: 102 DRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVE 161
           D +N   KL     D    +K L+ +L+ +  E  Q + +++T  V+ N     +  E+ 
Sbjct: 713 DLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIG 772

Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDL----QKLSISRQ 217
            L    ++H  +++ E + KE  ++K   Q+ ++   Y   N   RDL    Q + +SR+
Sbjct: 773 DLK--RRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRR 830

Query: 218 SICST 222
           S  S+
Sbjct: 831 SSTSS 835



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 32/160 (20%), Positives = 68/160 (42%), Gaps = 9/160 (5%)

Query: 53  KDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDK 112
           K+S      L++R R  + K +    +  + +   + +++  A      D    KSK D 
Sbjct: 117 KESSSTRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATE---CDVRMSKSKSDN 173

Query: 113 MNKDNSE---SLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKI 169
              D +     +K L    ++K+VE+L LR E+   +    +N   S  + +     +  
Sbjct: 174 QISDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMA 233

Query: 170 H---GLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKS 206
           H    +E  L  ++++ + ++ EL + K  +   +D L +
Sbjct: 234 HQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNA 273


>gi|224451080 cytospin A [Homo sapiens]
          Length = 1117

 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 44/185 (23%), Positives = 85/185 (45%), Gaps = 13/185 (7%)

Query: 46  EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYRE----VCI 101
           E+ KK+++D    N  L+K    L+EK   R + + +    E   + + A +     +  
Sbjct: 656 EEAKKQIEDL---NMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIIS 712

Query: 102 DRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVE 161
           D +N   KL     D    +K L+ +L+ +  E  Q + +++T  V+ N     +  E+ 
Sbjct: 713 DLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIG 772

Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDL----QKLSISRQ 217
            L    ++H  +++ E + KE  ++K   Q+ ++   Y   N   RDL    Q + +SR+
Sbjct: 773 DLK--RRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRR 830

Query: 218 SICST 222
           S  S+
Sbjct: 831 SSTSS 835



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 32/160 (20%), Positives = 68/160 (42%), Gaps = 9/160 (5%)

Query: 53  KDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDK 112
           K+S      L++R R  + K +    +  + +   + +++  A      D    KSK D 
Sbjct: 117 KESSSTRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATE---CDVRMSKSKSDN 173

Query: 113 MNKDNSE---SLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKI 169
              D +     +K L    ++K+VE+L LR E+   +    +N   S  + +     +  
Sbjct: 174 QISDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMA 233

Query: 170 H---GLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKS 206
           H    +E  L  ++++ + ++ EL + K  +   +D L +
Sbjct: 234 HQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNA 273


>gi|190194355 p90 autoantigen [Homo sapiens]
          Length = 905

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 40/163 (24%), Positives = 83/163 (50%), Gaps = 16/163 (9%)

Query: 33  ESVAS-HFALVTAYEDIKKRLKDSEKENSLLK----------KRIRFLEEKLIARFEEET 81
           ESVA  H  L  +Y ++ +R + +EK+N  L+          + ++ L E L  + E+  
Sbjct: 718 ESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSI 777

Query: 82  SS-VGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRT 140
           +  + +E+  K     +   +DR++  + L +  K   E +K L ++ + KE  +  LR 
Sbjct: 778 AQLIEKEEQRKEV---QNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRK 834

Query: 141 EVE-TQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKE 182
           E+  T+Q+ + L+  +S+ EV+K   + ++   E  ++L ++E
Sbjct: 835 ELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEE 877



 Score = 33.9 bits (76), Expect = 0.13
 Identities = 33/126 (26%), Positives = 64/126 (50%), Gaps = 9/126 (7%)

Query: 97  REVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMR-----NL 151
           +++ I  D+L  +++ + K N ESLK  NE+  ++ +E  + R EV+ Q V R     NL
Sbjct: 746 KDLQITCDSLNKQIETVKKLN-ESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANL 804

Query: 152 NPPSSNWEVEKLSCDLKIHGLEQELELMRKECS---DLKIELQKAKQTDPYQEDNLKSRD 208
           +  +   E +  +   +    E+ ++++RKE S    ++ EL     +   Q+  L+ R 
Sbjct: 805 HQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRL 864

Query: 209 LQKLSI 214
            +K S+
Sbjct: 865 EEKESL 870


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 43/171 (25%), Positives = 82/171 (47%), Gaps = 17/171 (9%)

Query: 48   IKKRLKDSEKENSLLKKRIRFL------EEKLIARFEEETSSVGREQVNKAYHAYREVCI 101
            ++K+L+D  KEN  L +++  L      + + I + E E       + N      R    
Sbjct: 894  LQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRY--- 950

Query: 102  DRDNLKSKLDKMNKDNSESLKVLNEQLQSK---EVELLQLRTEVETQQVMRNLNPPSSNW 158
             RD ++ KL K+ K NSE L+   EQ+Q K   + E L+ + +  T+Q+  ++       
Sbjct: 951  -RDAVEEKLAKLQKHNSE-LETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQR 1008

Query: 159  EVEKLSCDLKIHGLEQELELMRKE---CSDLKIELQKAKQTDPYQEDNLKS 206
             + + S +LK    E++++ +++E     D K++LQ   + +    D LK+
Sbjct: 1009 MLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKA 1059



 Score = 34.3 bits (77), Expect = 0.10
 Identities = 28/150 (18%), Positives = 68/150 (45%), Gaps = 18/150 (12%)

Query: 47   DIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNL 106
            D K+++ + EK+   L+ R+    EK+  + EE ++ + R Q             +    
Sbjct: 1213 DFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQE------------EEGTQ 1260

Query: 107  KSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCD 166
            +  L+  N+ +++  + L +++Q  +     L+ + ET+  ++       N+  E     
Sbjct: 1261 RKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVK------CNFRQEASRLT 1314

Query: 167  LKIHGLEQELELMRKECSDLKIELQKAKQT 196
            L+   LE+EL++  +    L+ +++   +T
Sbjct: 1315 LENRDLEEELDMKDRVIKKLQDQVKTLSKT 1344


>gi|38044112 restin isoform b [Homo sapiens]
          Length = 1392

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 48/186 (25%), Positives = 86/186 (46%), Gaps = 31/186 (16%)

Query: 46   EDIKKRLKDSEKENSLLKKRIRFLEEKLI---ARFEEETSSVGREQVNKAYHAYREVCID 102
            ++   +L   E++ ++L   +  L E L    A+F E+      EQ+ KA          
Sbjct: 829  QETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDER--EEQLIKAKEKL------ 880

Query: 103  RDNLKSKLDKMNKDNSESLKVLNEQLQSKE--VELLQLRT--------------EVETQQ 146
             +N  +++ KM+ DNS  L  +N++L+ KE  VE LQL+               E  T +
Sbjct: 881  -ENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVK 939

Query: 147  VMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKA-KQTDPYQEDNLK 205
              ++    +   E EK   + K+  LE+++E    +C +LK   ++A  +T    E+ L 
Sbjct: 940  AEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEIL- 998

Query: 206  SRDLQK 211
             ++LQK
Sbjct: 999  -QNLQK 1003



 Score = 35.0 bits (79), Expect = 0.059
 Identities = 52/203 (25%), Positives = 96/203 (47%), Gaps = 42/203 (20%)

Query: 32  DESVASHFALVTAYEDIK----KRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGRE 87
           + ++ASH     A E++K    K L     E + LK +I    EK+   ++ E  ++  +
Sbjct: 582 ETAIASH---QQAMEELKVSFSKGLGTETAEFAELKTQI----EKMRLDYQHEIENLQNQ 634

Query: 88  QVN-KAYHAYR---------EVCIDRDN----LKSKLDKMNKDN----SESLKVLNE-QL 128
           Q + +A HA           +V  +++N    ++SKLDK    +     ++L  L E ++
Sbjct: 635 QDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEI 694

Query: 129 QSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKI 188
           + KE+E+LQ +   +T +V+ N        E EKL           +L+ +RK  S+ K 
Sbjct: 695 KVKELEVLQAKCNEQT-KVIDNFTSQLKATE-EKL----------LDLDALRKASSEGKS 742

Query: 189 ELQKAKQTDPYQEDNLKSRDLQK 211
           E++K +Q     E  +K  +++K
Sbjct: 743 EMKKLRQQLEAAEKQIKHLEIEK 765



 Score = 34.7 bits (78), Expect = 0.077
 Identities = 34/141 (24%), Positives = 69/141 (48%), Gaps = 17/141 (12%)

Query: 63  KKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLK 122
           ++ I  L+E   AR  EET    ++++   Y A  ++  + ++LKSKL+  NK+NS+ + 
Sbjct: 521 QREITSLKEHFGAR--EETH---QKEIKALYTATEKLSKENESLKSKLEHANKENSDVIA 575

Query: 123 VLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNW-----EVEKLSCDL--KIHGLEQE 175
           +   +L++      Q   E++     + L   ++ +     ++EK+  D   +I  L+ +
Sbjct: 576 LWKSKLETAIASHQQAMEELKV-SFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQ 634

Query: 176 LELMR----KECSDLKIELQK 192
            +  R    KE   L+ +L K
Sbjct: 635 QDSERAAHAKEMEALRAKLMK 655


>gi|4506751 restin isoform a [Homo sapiens]
          Length = 1427

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 48/186 (25%), Positives = 86/186 (46%), Gaps = 31/186 (16%)

Query: 46   EDIKKRLKDSEKENSLLKKRIRFLEEKLI---ARFEEETSSVGREQVNKAYHAYREVCID 102
            ++   +L   E++ ++L   +  L E L    A+F E+      EQ+ KA          
Sbjct: 864  QETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDER--EEQLIKAKEKL------ 915

Query: 103  RDNLKSKLDKMNKDNSESLKVLNEQLQSKE--VELLQLRT--------------EVETQQ 146
             +N  +++ KM+ DNS  L  +N++L+ KE  VE LQL+               E  T +
Sbjct: 916  -ENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVK 974

Query: 147  VMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKA-KQTDPYQEDNLK 205
              ++    +   E EK   + K+  LE+++E    +C +LK   ++A  +T    E+ L 
Sbjct: 975  AEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEIL- 1033

Query: 206  SRDLQK 211
             ++LQK
Sbjct: 1034 -QNLQK 1038



 Score = 35.0 bits (79), Expect = 0.059
 Identities = 52/203 (25%), Positives = 96/203 (47%), Gaps = 42/203 (20%)

Query: 32  DESVASHFALVTAYEDIK----KRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGRE 87
           + ++ASH     A E++K    K L     E + LK +I    EK+   ++ E  ++  +
Sbjct: 617 ETAIASH---QQAMEELKVSFSKGLGTETAEFAELKTQI----EKMRLDYQHEIENLQNQ 669

Query: 88  QVN-KAYHAYR---------EVCIDRDN----LKSKLDKMNKDN----SESLKVLNE-QL 128
           Q + +A HA           +V  +++N    ++SKLDK    +     ++L  L E ++
Sbjct: 670 QDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEI 729

Query: 129 QSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKI 188
           + KE+E+LQ +   +T +V+ N        E EKL           +L+ +RK  S+ K 
Sbjct: 730 KVKELEVLQAKCNEQT-KVIDNFTSQLKATE-EKL----------LDLDALRKASSEGKS 777

Query: 189 ELQKAKQTDPYQEDNLKSRDLQK 211
           E++K +Q     E  +K  +++K
Sbjct: 778 EMKKLRQQLEAAEKQIKHLEIEK 800



 Score = 34.7 bits (78), Expect = 0.077
 Identities = 34/141 (24%), Positives = 69/141 (48%), Gaps = 17/141 (12%)

Query: 63  KKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLK 122
           ++ I  L+E   AR  EET    ++++   Y A  ++  + ++LKSKL+  NK+NS+ + 
Sbjct: 556 QREITSLKEHFGAR--EETH---QKEIKALYTATEKLSKENESLKSKLEHANKENSDVIA 610

Query: 123 VLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNW-----EVEKLSCDL--KIHGLEQE 175
           +   +L++      Q   E++     + L   ++ +     ++EK+  D   +I  L+ +
Sbjct: 611 LWKSKLETAIASHQQAMEELKV-SFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQ 669

Query: 176 LELMR----KECSDLKIELQK 192
            +  R    KE   L+ +L K
Sbjct: 670 QDSERAAHAKEMEALRAKLMK 690


>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
           sapiens]
          Length = 1116

 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 34/163 (20%)

Query: 46  EDIKKRLKDSEKENSLLKKRIRFLE-------------EKLIARFEEETSSVGREQVNKA 92
           E+++++L+D EK+ S LK+R++ L+             E+ +A  +E T    +EQ ++ 
Sbjct: 581 ENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAE-KERTIERLKEQRDRD 639

Query: 93  YHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLN 152
               +E   + DN K  L    KD  E + +L   L  KE  LL L+             
Sbjct: 640 EREKQE---EIDNYKKDL----KDLKEKVSLLQGDLSEKEASLLDLKEH----------- 681

Query: 153 PPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQ 195
             +S+     L  D ++  LE  LE  ++EC  ++ +L+KA +
Sbjct: 682 --ASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHE 722



 Score = 36.6 bits (83), Expect = 0.020
 Identities = 39/170 (22%), Positives = 81/170 (47%), Gaps = 23/170 (13%)

Query: 47  DIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNL 106
           D++ +LK+  +EN LL+K +   E KL       +SS+   +   +    +E  + +D  
Sbjct: 153 DLQTQLKEVLRENDLLRKDVEVKESKL-------SSSMNSIKTFWSPELKKERALRKDE- 204

Query: 107 KSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNL-NPPSSNWEVEKLSC 165
            SK+        E  +V+ E+ Q  ++ +  L+ E+  Q+ +  L    SS+   E    
Sbjct: 205 ASKITIW----KEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVA 260

Query: 166 DL------KIHGLEQ----ELELMRKECSDLKIELQKAKQTDPYQEDNLK 205
           +L      ++H   +    EL L+RK   ++++ ++  KQT   +++++K
Sbjct: 261 ELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIK 310



 Score = 34.3 bits (77), Expect = 0.10
 Identities = 48/200 (24%), Positives = 89/200 (44%), Gaps = 32/200 (16%)

Query: 46  EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDN 105
           E +K+ L   E +   LKK+   L+ + I + ++E S    E +                
Sbjct: 441 EQLKEELSSKEAQWEELKKKAAGLQAE-IGQVKQELSRKDTELLA--------------- 484

Query: 106 LKSKLDKMNK---DNSESLKVLNEQLQSKEVELLQLRTEV--------ETQQVMRNLNPP 154
           L++KL+ +     D+ + ++VL E L +KE     L+TEV        E + ++      
Sbjct: 485 LQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQ 544

Query: 155 SSNWEVEKLSCDLKIHGLEQELELMRKECSDL--KIE-LQKAKQTDPYQEDNLKSR--DL 209
             +   EK +   +IH L+  L++  ++ + L  KIE LQ+  +    Q  +LK R   L
Sbjct: 545 IQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSL 604

Query: 210 QKLSISRQSICSTAWSAVAQ 229
           Q  + +  +  +T   A+A+
Sbjct: 605 QADTTNTDTALTTLEEALAE 624


>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
          Length = 1088

 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 34/163 (20%)

Query: 46  EDIKKRLKDSEKENSLLKKRIRFLE-------------EKLIARFEEETSSVGREQVNKA 92
           E+++++L+D EK+ S LK+R++ L+             E+ +A  +E T    +EQ ++ 
Sbjct: 553 ENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAE-KERTIERLKEQRDRD 611

Query: 93  YHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLN 152
               +E   + DN K  L    KD  E + +L   L  KE  LL L+             
Sbjct: 612 EREKQE---EIDNYKKDL----KDLKEKVSLLQGDLSEKEASLLDLKEH----------- 653

Query: 153 PPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQ 195
             +S+     L  D ++  LE  LE  ++EC  ++ +L+KA +
Sbjct: 654 --ASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHE 694



 Score = 36.6 bits (83), Expect = 0.020
 Identities = 39/170 (22%), Positives = 81/170 (47%), Gaps = 23/170 (13%)

Query: 47  DIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNL 106
           D++ +LK+  +EN LL+K +   E KL       +SS+   +   +    +E  + +D  
Sbjct: 153 DLQTQLKEVLRENDLLRKDVEVKESKL-------SSSMNSIKTFWSPELKKERALRKDE- 204

Query: 107 KSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNL-NPPSSNWEVEKLSC 165
            SK+        E  +V+ E+ Q  ++ +  L+ E+  Q+ +  L    SS+   E    
Sbjct: 205 ASKITIW----KEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVA 260

Query: 166 DL------KIHGLEQ----ELELMRKECSDLKIELQKAKQTDPYQEDNLK 205
           +L      ++H   +    EL L+RK   ++++ ++  KQT   +++++K
Sbjct: 261 ELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIK 310



 Score = 33.5 bits (75), Expect = 0.17
 Identities = 54/243 (22%), Positives = 103/243 (42%), Gaps = 36/243 (14%)

Query: 15  EKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLI 74
           E+ H+R    P S        A   AL T  E    ++   E+    L++ I+ L+    
Sbjct: 362 EEMHRRFENAPDS--------AKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGA 413

Query: 75  ARFEEETSSVGREQVNKAYHAYREVCIDRDN------------LKSKLDKMNK---DNSE 119
              EE    + + +V +++  + +  I +              L++KL+ +     D+ +
Sbjct: 414 LSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQ 473

Query: 120 SLKVLNEQLQSKEVELLQLRTEV--------ETQQVMRNLNPPSSNWEVEKLSCDLKIHG 171
            ++VL E L +KE     L+TEV        E + ++        +   EK +   +IH 
Sbjct: 474 HIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHD 533

Query: 172 LEQELELMRKECSDL--KIE-LQKAKQTDPYQEDNLKSR--DLQKLSISRQSICSTAWSA 226
           L+  L++  ++ + L  KIE LQ+  +    Q  +LK R   LQ  + +  +  +T   A
Sbjct: 534 LKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEA 593

Query: 227 VAQ 229
           +A+
Sbjct: 594 LAE 596


>gi|18390344 ATR interacting protein isoform 2 [Homo sapiens]
          Length = 764

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 12/115 (10%)

Query: 41  LVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVC 100
           L   Y+++K+++K  E+E  +    I+ L + L      +T SV  EQ    +       
Sbjct: 117 LQAQYKELKEKMKVMEEEVLIKNGEIKILRDSL-----HQTESVLEEQRRSHF------L 165

Query: 101 IDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPS 155
           ++++  ++  DK  K+ S+ L+ L  +LQ K+ E+ +LRT+++T +    L  PS
Sbjct: 166 LEQEKTQALSDK-EKEFSKKLQSLQSELQFKDAEMNELRTKLQTSERANKLAAPS 219


>gi|18390347 ATR interacting protein isoform 1 [Homo sapiens]
          Length = 791

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 12/115 (10%)

Query: 41  LVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVC 100
           L   Y+++K+++K  E+E  +    I+ L + L      +T SV  EQ    +       
Sbjct: 117 LQAQYKELKEKMKVMEEEVLIKNGEIKILRDSL-----HQTESVLEEQRRSHF------L 165

Query: 101 IDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPS 155
           ++++  ++  DK  K+ S+ L+ L  +LQ K+ E+ +LRT+++T +    L  PS
Sbjct: 166 LEQEKTQALSDK-EKEFSKKLQSLQSELQFKDAEMNELRTKLQTSERANKLAAPS 219


>gi|110815815 centlein isoform 1 [Homo sapiens]
          Length = 1406

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 54/205 (26%), Positives = 98/205 (47%), Gaps = 36/205 (17%)

Query: 54  DSEKENSLLKKR----IRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLK-- 107
           + EK+ S  K R    I  +++  I  FE+   SV ++++N      R++ +D +N    
Sbjct: 149 EREKQKSEAKDRKVLEILQVKDAKIQEFEQR-ESVLKQEINDLVK--RKIAVDEENAFLR 205

Query: 108 ---SKLDKMNKDNSESLKVLNEQLQSKEVE--LLQLRTEVETQQV----------MRNLN 152
              S L+K  KD S+ +K   E +Q+KE +  L+    E E +++          +  L 
Sbjct: 206 KEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRLVIKNLEEENKKLSTRCTDLLNDLEKLR 265

Query: 153 PPSSNWEVEKLSCDLKIHGLE-------QELELMRKECSDLKIELQKAKQTDPYQED--- 202
              ++   EK S D KI   E       +E+E+ + + + L ++L   KQT+  Q+D   
Sbjct: 266 KQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALSLQLSN-KQTELIQKDMDI 324

Query: 203 NLKSRDLQKL-SISRQSICSTAWSA 226
            L  ++LQ+L ++ +Q+   TA  A
Sbjct: 325 TLVRKELQELQNLYKQNSTHTAQQA 349



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 45/186 (24%), Positives = 80/186 (43%), Gaps = 22/186 (11%)

Query: 47  DIKKRLKDSEKENSLLKKRIRFLEEKL------------IARFEEETSSVGREQVNKAYH 94
           D+ KR    ++EN+ L+K    LE+K               + +EE + +  + + +   
Sbjct: 189 DLVKRKIAVDEENAFLRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRLVIKNLEEENK 248

Query: 95  AYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRN-LNP 153
                C D  N   KL K      +     + ++++ E  L++ R EVE  Q   N L+ 
Sbjct: 249 KLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALSL 308

Query: 154 PSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLS 213
             SN + E +  D+       ++ L+RKE  +L+  L K   T   Q+  L  + LQ L+
Sbjct: 309 QLSNKQTELIQKDM-------DITLVRKELQELQ-NLYKQNSTHTAQQAEL-IQQLQVLN 359

Query: 214 ISRQSI 219
           +  Q +
Sbjct: 360 MDTQKV 365


>gi|167555106 centlein isoform 2 [Homo sapiens]
          Length = 391

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 54/205 (26%), Positives = 98/205 (47%), Gaps = 36/205 (17%)

Query: 54  DSEKENSLLKKR----IRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLK-- 107
           + EK+ S  K R    I  +++  I  FE+   SV ++++N      R++ +D +N    
Sbjct: 149 EREKQKSEAKDRKVLEILQVKDAKIQEFEQR-ESVLKQEINDLVK--RKIAVDEENAFLR 205

Query: 108 ---SKLDKMNKDNSESLKVLNEQLQSKEVE--LLQLRTEVETQQV----------MRNLN 152
              S L+K  KD S+ +K   E +Q+KE +  L+    E E +++          +  L 
Sbjct: 206 KEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRLVIKNLEEENKKLSTRCTDLLNDLEKLR 265

Query: 153 PPSSNWEVEKLSCDLKIHGLE-------QELELMRKECSDLKIELQKAKQTDPYQED--- 202
              ++   EK S D KI   E       +E+E+ + + + L ++L   KQT+  Q+D   
Sbjct: 266 KQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALSLQLSN-KQTELIQKDMDI 324

Query: 203 NLKSRDLQKL-SISRQSICSTAWSA 226
            L  ++LQ+L ++ +Q+   TA  A
Sbjct: 325 TLVRKELQELQNLYKQNSTHTAQQA 349



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 45/186 (24%), Positives = 80/186 (43%), Gaps = 22/186 (11%)

Query: 47  DIKKRLKDSEKENSLLKKRIRFLEEKL------------IARFEEETSSVGREQVNKAYH 94
           D+ KR    ++EN+ L+K    LE+K               + +EE + +  + + +   
Sbjct: 189 DLVKRKIAVDEENAFLRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRLVIKNLEEENK 248

Query: 95  AYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRN-LNP 153
                C D  N   KL K      +     + ++++ E  L++ R EVE  Q   N L+ 
Sbjct: 249 KLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALSL 308

Query: 154 PSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLS 213
             SN + E +  D+       ++ L+RKE  +L+  L K   T   Q+  L  + LQ L+
Sbjct: 309 QLSNKQTELIQKDM-------DITLVRKELQELQ-NLYKQNSTHTAQQAEL-IQQLQVLN 359

Query: 214 ISRQSI 219
           +  Q +
Sbjct: 360 MDTQKV 365


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 41/148 (27%), Positives = 68/148 (45%), Gaps = 20/148 (13%)

Query: 15  EKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLL----KKRIRFLE 70
           +K HK +        SGD +V  +   V   +D+ K L D  +E   L    +K I    
Sbjct: 289 KKNHKEEMSQLTGQNSGDVNVEIN---VAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQY 345

Query: 71  EKLIARFEEETSSVGRE------QVNKAYHAYREVCIDRDNLKSK---LDKMNKDNSE-- 119
           E  I + E E SS G+E      +V +  H  +E+ I+  +  SK   L+K  +D     
Sbjct: 346 ETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRY 405

Query: 120 --SLKVLNEQLQSKEVELLQLRTEVETQ 145
              L+++ EQ+ + E ++  +R E+E Q
Sbjct: 406 CGQLQMIQEQISNLEAQITDVRQEIECQ 433



 Score = 27.7 bits (60), Expect = 9.4
 Identities = 30/150 (20%), Positives = 64/150 (42%), Gaps = 24/150 (16%)

Query: 46  EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDN 105
           +++  RL     +   L++    LE K+   ++++    G   + K Y  Y       D+
Sbjct: 158 QELNSRLASYLDKVQALEEANNDLENKIQDWYDKK----GPAAIQKNYSPYYNTI---DD 210

Query: 106 LKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSC 165
           LK ++  +   N+++L      + +  + L   R + E +Q +R                
Sbjct: 211 LKDQIVDLTVGNNKTLL----DIDNTRMTLDDFRIKFEMEQNLRQ-------------GV 253

Query: 166 DLKIHGLEQELELMRKECSDLKIELQKAKQ 195
           D  I+GL Q L+ +  E SDL+++ +  ++
Sbjct: 254 DADINGLRQVLDNLTMEKSDLEMQYETLQE 283


>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
          Length = 1417

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 43/187 (22%), Positives = 88/187 (47%), Gaps = 16/187 (8%)

Query: 38  HFALVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYR 97
           H  +  A+E  KK   +  KE     +R+    EK   +F+E+  ++   Q +     + 
Sbjct: 745 HEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHH 804

Query: 98  EVCIDR--DNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVE--TQQVMRNLNP 153
              +DR     K ++ K N    E+LK L  Q+  + +++ QL + +E   ++++ +LN 
Sbjct: 805 LESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQ 864

Query: 154 PSSNWEVEKLSCDLK-----IHGLEQELELMR---KECSDLKIELQKA--KQTDPYQEDN 203
              N   EK    LK     ++ L++EL++     +E S+  + LQ    +Q    Q++ 
Sbjct: 865 LEGN--KEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQET 922

Query: 204 LKSRDLQ 210
           +++ +L+
Sbjct: 923 IRNGELE 929



 Score = 35.8 bits (81), Expect = 0.035
 Identities = 36/176 (20%), Positives = 80/176 (45%), Gaps = 18/176 (10%)

Query: 54  DSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCI----DRDNLKSK 109
           + +KEN    + ++ L+ ++     EET  V   Q++ A    +E  +      +  K K
Sbjct: 818 EMKKENMKKDEALKALQNQV----SEETIKV--RQLDSALEICKEELVLHLNQLEGNKEK 871

Query: 110 LDKMNKDNSES-------LKVLNEQLQ-SKEVELLQLRTEVETQQVMRNLNPPSSNWEVE 161
            +K  K  SE        LK+ N  LQ + E  ++   T  + QQ+++     +   E  
Sbjct: 872 FEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDT 931

Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRQ 217
           +   + ++  LEQEL+  R+  ++   ++++  ++  ++ D  + + ++    +RQ
Sbjct: 932 QTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQ 987



 Score = 33.5 bits (75), Expect = 0.17
 Identities = 44/176 (25%), Positives = 70/176 (39%), Gaps = 35/176 (19%)

Query: 41  LVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVC 100
           LVT  E+++ +L   E ENS LK                    V        +   +E  
Sbjct: 639 LVTGIEELRTKLIQIEAENSDLK--------------------VNMAHRTSQFQLIQEEL 678

Query: 101 IDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTE--------VETQQVMRNLN 152
           +++ +  SKL+         L  L +QL+ K V    +  +        +E  + +R+L 
Sbjct: 679 LEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLE 738

Query: 153 PPSSNWEVEKLSCDL----KIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNL 204
             + N E EK+        KIH LEQ  E M K+   L+ +L+K  Q    QE  +
Sbjct: 739 -TNINTEHEKICLAFEKAKKIH-LEQHKE-MEKQIERLEAQLEKKDQQFKEQEKTM 791



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 29/112 (25%), Positives = 48/112 (42%), Gaps = 6/112 (5%)

Query: 41   LVTAYEDIKKRLKDSEKENSLLKKRI---RFLEEKLIARFEEETSSVGREQVNKAYHAYR 97
            L +  ED+K+  K+ +   + L + +   +  E  L AR + E   +  E V     AY 
Sbjct: 1286 LSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAE-VESLKEAYH 1344

Query: 98   EVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVET--QQV 147
               I      +K          S++ LNEQL+  ++EL + +  V    QQV
Sbjct: 1345 MEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQV 1396


>gi|19743571 TRAF interacting protein TANK isoform b [Homo sapiens]
          Length = 119

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 17/56 (30%), Positives = 37/56 (66%)

Query: 87  EQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEV 142
           EQ+NKAY A+R+ C+DRD+   +L +  ++  + ++   EQL  ++  + +L++++
Sbjct: 7   EQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKSQL 62


>gi|19743569 TRAF interacting protein TANK isoform a [Homo sapiens]
          Length = 425

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 17/56 (30%), Positives = 37/56 (66%)

Query: 87  EQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEV 142
           EQ+NKAY A+R+ C+DRD+   +L +  ++  + ++   EQL  ++  + +L++++
Sbjct: 7   EQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKSQL 62


>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
          Length = 983

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 58/233 (24%), Positives = 108/233 (46%), Gaps = 45/233 (19%)

Query: 11  ILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYED----IKKRLKDSEKENSLLKKRI 66
           +L+ +K  K   V+P S+ +      SHF  +   E+    +K+ L+++ +E+   K+++
Sbjct: 502 VLSVQKQMKLGLVSPESMDN-----YSHFHELRVTEEEINVLKQDLQNALEESERNKEKV 556

Query: 67  RFLEEKLIAR------------FEEETSS-------VGREQV---NKAYHAYREVCIDRD 104
           R LEEKL+ R            +EE  SS       + +E+     K   A  E+   +D
Sbjct: 557 RELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 616

Query: 105 NLKSKLDKMNKDNSESLKV----LNEQLQSKEVELLQL----RTEVETQQVMRNLNPPSS 156
            LKS++ +   D +E +K     + ++L  +  EL QL    + E+E  +  ++L   ++
Sbjct: 617 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 676

Query: 157 NW----EVEKLS--CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDN 203
            +    E EKL    ++     E  L  M+ + S +  EL + KQ    Q++N
Sbjct: 677 EYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKEN 729



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 52/246 (21%), Positives = 106/246 (43%), Gaps = 29/246 (11%)

Query: 14  HEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSL-----------L 62
           HEK  +   V+          + S ++ V       K+L D++KENS+           L
Sbjct: 684 HEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTL 743

Query: 63  KKRIRFLEEKL------IARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKD 116
           +   + +EEK+      +A  E E + +  +Q+ +   A  +  + R + +     +  +
Sbjct: 744 RTAAKEMEEKISNLKEHLASKEVEVAKL-EKQLLEEKAAMTDAMVPRSSYEKLQSSLESE 802

Query: 117 NSESLKVLNEQLQSKE---VELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLE 173
            S     L E ++ KE    E++Q+R+EV   QV R       N +    S + +++ L 
Sbjct: 803 VSVLASKLKESVKEKEKVHSEVVQIRSEV--SQVKRE----KENIQTLLKSKEQEVNELL 856

Query: 174 QELELMRKECSDLK--IELQKAKQTDPYQEDNLKSRDLQKLSISRQSICSTAWSAVAQSW 231
           Q+ +  ++E +++K   E     + D  ++ N  S+++ KL  +  S+   ++S  +   
Sbjct: 857 QKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKR 916

Query: 232 DSMNFE 237
            S   E
Sbjct: 917 QSQQLE 922


>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
          Length = 972

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 58/233 (24%), Positives = 108/233 (46%), Gaps = 45/233 (19%)

Query: 11  ILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYED----IKKRLKDSEKENSLLKKRI 66
           +L+ +K  K   V+P S+ +      SHF  +   E+    +K+ L+++ +E+   K+++
Sbjct: 491 VLSVQKQMKLGLVSPESMDN-----YSHFHELRVTEEEINVLKQDLQNALEESERNKEKV 545

Query: 67  RFLEEKLIAR------------FEEETSS-------VGREQV---NKAYHAYREVCIDRD 104
           R LEEKL+ R            +EE  SS       + +E+     K   A  E+   +D
Sbjct: 546 RELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 605

Query: 105 NLKSKLDKMNKDNSESLKV----LNEQLQSKEVELLQL----RTEVETQQVMRNLNPPSS 156
            LKS++ +   D +E +K     + ++L  +  EL QL    + E+E  +  ++L   ++
Sbjct: 606 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 665

Query: 157 NW----EVEKLS--CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDN 203
            +    E EKL    ++     E  L  M+ + S +  EL + KQ    Q++N
Sbjct: 666 EYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKEN 718



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 52/246 (21%), Positives = 106/246 (43%), Gaps = 29/246 (11%)

Query: 14  HEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSL-----------L 62
           HEK  +   V+          + S ++ V       K+L D++KENS+           L
Sbjct: 673 HEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTL 732

Query: 63  KKRIRFLEEKL------IARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKD 116
           +   + +EEK+      +A  E E + +  +Q+ +   A  +  + R + +     +  +
Sbjct: 733 RTAAKEMEEKISNLKEHLASKEVEVAKL-EKQLLEEKAAMTDAMVPRSSYEKLQSSLESE 791

Query: 117 NSESLKVLNEQLQSKE---VELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLE 173
            S     L E ++ KE    E++Q+R+EV   QV R       N +    S + +++ L 
Sbjct: 792 VSVLASKLKESVKEKEKVHSEVVQIRSEV--SQVKRE----KENIQTLLKSKEQEVNELL 845

Query: 174 QELELMRKECSDLK--IELQKAKQTDPYQEDNLKSRDLQKLSISRQSICSTAWSAVAQSW 231
           Q+ +  ++E +++K   E     + D  ++ N  S+++ KL  +  S+   ++S  +   
Sbjct: 846 QKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKR 905

Query: 232 DSMNFE 237
            S   E
Sbjct: 906 QSQQLE 911


>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
          Length = 951

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 58/233 (24%), Positives = 108/233 (46%), Gaps = 45/233 (19%)

Query: 11  ILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYED----IKKRLKDSEKENSLLKKRI 66
           +L+ +K  K   V+P S+ +      SHF  +   E+    +K+ L+++ +E+   K+++
Sbjct: 470 VLSVQKQMKLGLVSPESMDN-----YSHFHELRVTEEEINVLKQDLQNALEESERNKEKV 524

Query: 67  RFLEEKLIAR------------FEEETSS-------VGREQV---NKAYHAYREVCIDRD 104
           R LEEKL+ R            +EE  SS       + +E+     K   A  E+   +D
Sbjct: 525 RELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 584

Query: 105 NLKSKLDKMNKDNSESLKV----LNEQLQSKEVELLQL----RTEVETQQVMRNLNPPSS 156
            LKS++ +   D +E +K     + ++L  +  EL QL    + E+E  +  ++L   ++
Sbjct: 585 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 644

Query: 157 NW----EVEKLS--CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDN 203
            +    E EKL    ++     E  L  M+ + S +  EL + KQ    Q++N
Sbjct: 645 EYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKEN 697



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 52/246 (21%), Positives = 106/246 (43%), Gaps = 29/246 (11%)

Query: 14  HEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSL-----------L 62
           HEK  +   V+          + S ++ V       K+L D++KENS+           L
Sbjct: 652 HEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTL 711

Query: 63  KKRIRFLEEKL------IARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKD 116
           +   + +EEK+      +A  E E + +  +Q+ +   A  +  + R + +     +  +
Sbjct: 712 RTAAKEMEEKISNLKEHLASKEVEVAKL-EKQLLEEKAAMTDAMVPRSSYEKLQSSLESE 770

Query: 117 NSESLKVLNEQLQSKE---VELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLE 173
            S     L E ++ KE    E++Q+R+EV   QV R       N +    S + +++ L 
Sbjct: 771 VSVLASKLKESVKEKEKVHSEVVQIRSEV--SQVKRE----KENIQTLLKSKEQEVNELL 824

Query: 174 QELELMRKECSDLK--IELQKAKQTDPYQEDNLKSRDLQKLSISRQSICSTAWSAVAQSW 231
           Q+ +  ++E +++K   E     + D  ++ N  S+++ KL  +  S+   ++S  +   
Sbjct: 825 QKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKR 884

Query: 232 DSMNFE 237
            S   E
Sbjct: 885 QSQQLE 890


>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 58/233 (24%), Positives = 108/233 (46%), Gaps = 45/233 (19%)

Query: 11  ILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYED----IKKRLKDSEKENSLLKKRI 66
           +L+ +K  K   V+P S+ +      SHF  +   E+    +K+ L+++ +E+   K+++
Sbjct: 499 VLSVQKQMKLGLVSPESMDN-----YSHFHELRVTEEEINVLKQDLQNALEESERNKEKV 553

Query: 67  RFLEEKLIAR------------FEEETSS-------VGREQV---NKAYHAYREVCIDRD 104
           R LEEKL+ R            +EE  SS       + +E+     K   A  E+   +D
Sbjct: 554 RELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 613

Query: 105 NLKSKLDKMNKDNSESLKV----LNEQLQSKEVELLQL----RTEVETQQVMRNLNPPSS 156
            LKS++ +   D +E +K     + ++L  +  EL QL    + E+E  +  ++L   ++
Sbjct: 614 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 673

Query: 157 NW----EVEKLS--CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDN 203
            +    E EKL    ++     E  L  M+ + S +  EL + KQ    Q++N
Sbjct: 674 EYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKEN 726



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 52/246 (21%), Positives = 106/246 (43%), Gaps = 29/246 (11%)

Query: 14  HEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSL-----------L 62
           HEK  +   V+          + S ++ V       K+L D++KENS+           L
Sbjct: 681 HEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTL 740

Query: 63  KKRIRFLEEKL------IARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKD 116
           +   + +EEK+      +A  E E + +  +Q+ +   A  +  + R + +     +  +
Sbjct: 741 RTAAKEMEEKISNLKEHLASKEVEVAKL-EKQLLEEKAAMTDAMVPRSSYEKLQSSLESE 799

Query: 117 NSESLKVLNEQLQSKE---VELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLE 173
            S     L E ++ KE    E++Q+R+EV   QV R       N +    S + +++ L 
Sbjct: 800 VSVLASKLKESVKEKEKVHSEVVQIRSEV--SQVKRE----KENIQTLLKSKEQEVNELL 853

Query: 174 QELELMRKECSDLK--IELQKAKQTDPYQEDNLKSRDLQKLSISRQSICSTAWSAVAQSW 231
           Q+ +  ++E +++K   E     + D  ++ N  S+++ KL  +  S+   ++S  +   
Sbjct: 854 QKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKR 913

Query: 232 DSMNFE 237
            S   E
Sbjct: 914 QSQQLE 919


>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 58/233 (24%), Positives = 108/233 (46%), Gaps = 45/233 (19%)

Query: 11  ILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYED----IKKRLKDSEKENSLLKKRI 66
           +L+ +K  K   V+P S+ +      SHF  +   E+    +K+ L+++ +E+   K+++
Sbjct: 499 VLSVQKQMKLGLVSPESMDN-----YSHFHELRVTEEEINVLKQDLQNALEESERNKEKV 553

Query: 67  RFLEEKLIAR------------FEEETSS-------VGREQV---NKAYHAYREVCIDRD 104
           R LEEKL+ R            +EE  SS       + +E+     K   A  E+   +D
Sbjct: 554 RELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 613

Query: 105 NLKSKLDKMNKDNSESLKV----LNEQLQSKEVELLQL----RTEVETQQVMRNLNPPSS 156
            LKS++ +   D +E +K     + ++L  +  EL QL    + E+E  +  ++L   ++
Sbjct: 614 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 673

Query: 157 NW----EVEKLS--CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDN 203
            +    E EKL    ++     E  L  M+ + S +  EL + KQ    Q++N
Sbjct: 674 EYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKEN 726



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 52/246 (21%), Positives = 106/246 (43%), Gaps = 29/246 (11%)

Query: 14  HEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSL-----------L 62
           HEK  +   V+          + S ++ V       K+L D++KENS+           L
Sbjct: 681 HEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTL 740

Query: 63  KKRIRFLEEKL------IARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKD 116
           +   + +EEK+      +A  E E + +  +Q+ +   A  +  + R + +     +  +
Sbjct: 741 RTAAKEMEEKISNLKEHLASKEVEVAKL-EKQLLEEKAAMTDAMVPRSSYEKLQSSLESE 799

Query: 117 NSESLKVLNEQLQSKE---VELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLE 173
            S     L E ++ KE    E++Q+R+EV   QV R       N +    S + +++ L 
Sbjct: 800 VSVLASKLKESVKEKEKVHSEVVQIRSEV--SQVKRE----KENIQTLLKSKEQEVNELL 853

Query: 174 QELELMRKECSDLK--IELQKAKQTDPYQEDNLKSRDLQKLSISRQSICSTAWSAVAQSW 231
           Q+ +  ++E +++K   E     + D  ++ N  S+++ KL  +  S+   ++S  +   
Sbjct: 854 QKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKR 913

Query: 232 DSMNFE 237
            S   E
Sbjct: 914 QSQQLE 919


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.127    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,700,658
Number of Sequences: 37866
Number of extensions: 363076
Number of successful extensions: 2595
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 69
Number of HSP's successfully gapped in prelim test: 417
Number of HSP's that attempted gapping in prelim test: 1845
Number of HSP's gapped (non-prelim): 1059
length of query: 243
length of database: 18,247,518
effective HSP length: 99
effective length of query: 144
effective length of database: 14,498,784
effective search space: 2087824896
effective search space used: 2087824896
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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