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Search of human proteins with 197276674
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|197276674 cyclin J isoform 1 [Homo sapiens]
(383 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|197276674 cyclin J isoform 1 [Homo sapiens] 785 0.0
gi|40254889 cyclin J isoform 2 [Homo sapiens] 753 0.0
gi|197276676 cyclin J isoform 3 [Homo sapiens] 751 0.0
gi|94680985 cyclin J-like [Homo sapiens] 285 4e-77
gi|161377472 cyclin A1 isoform c [Homo sapiens] 78 2e-14
gi|161377470 cyclin A1 isoform c [Homo sapiens] 78 2e-14
gi|161377468 cyclin A1 isoform b [Homo sapiens] 78 2e-14
gi|4502611 cyclin A1 isoform a [Homo sapiens] 78 2e-14
gi|4502613 cyclin A [Homo sapiens] 71 1e-12
gi|4757930 cyclin B2 [Homo sapiens] 66 6e-11
gi|16950655 cyclin D1 [Homo sapiens] 64 2e-10
gi|153791755 cyclin domain containing [Homo sapiens] 62 1e-09
gi|14327896 cyclin B1 [Homo sapiens] 58 2e-08
gi|4502619 cyclin D3 isoform 2 [Homo sapiens] 55 8e-08
gi|5802992 cyclin I [Homo sapiens] 54 2e-07
gi|4502617 cyclin D2 [Homo sapiens] 54 2e-07
gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 54 2e-07
gi|209862835 cyclin D3 isoform 1 [Homo sapiens] 54 3e-07
gi|16306525 cyclin B3 isoform 1 [Homo sapiens] 52 7e-07
gi|17318565 cyclin E2 [Homo sapiens] 49 6e-06
gi|40805832 cyclin G1 [Homo sapiens] 49 8e-06
gi|4757934 cyclin G1 [Homo sapiens] 49 8e-06
gi|118572588 cyclin F [Homo sapiens] 49 1e-05
gi|89886237 cyclin I family, member 2 [Homo sapiens] 43 5e-04
gi|209915553 cyclin D3 isoform 3 [Homo sapiens] 42 0.001
gi|17318559 cyclin E1 isoform 1 [Homo sapiens] 39 0.008
gi|17318561 cyclin E1 isoform 2 [Homo sapiens] 39 0.008
gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho... 39 0.010
gi|4757936 cyclin G2 [Homo sapiens] 38 0.017
gi|4502623 cyclin H [Homo sapiens] 38 0.017
>gi|197276674 cyclin J isoform 1 [Homo sapiens]
Length = 383
Score = 785 bits (2026), Expect = 0.0
Identities = 383/383 (100%), Positives = 383/383 (100%)
Query: 1 MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA 60
MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA
Sbjct: 1 MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA 60
Query: 61 RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL
Sbjct: 61 RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
Query: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180
VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM
Sbjct: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180
Query: 181 AKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ 240
AKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ
Sbjct: 181 AKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ 240
Query: 241 CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ 300
CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ
Sbjct: 241 CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ 300
Query: 301 YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL 360
YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL
Sbjct: 301 YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL 360
Query: 361 SVSYNRSYQINEHYPCITPCFER 383
SVSYNRSYQINEHYPCITPCFER
Sbjct: 361 SVSYNRSYQINEHYPCITPCFER 383
>gi|40254889 cyclin J isoform 2 [Homo sapiens]
Length = 372
Score = 753 bits (1945), Expect = 0.0
Identities = 372/383 (97%), Positives = 372/383 (97%), Gaps = 11/383 (2%)
Query: 1 MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA 60
MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA
Sbjct: 1 MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA 60
Query: 61 RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL
Sbjct: 61 RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
Query: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180
VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM
Sbjct: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180
Query: 181 AKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ 240
AKYADYFLEVSLQ VAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ
Sbjct: 181 AKYADYFLEVSLQ-----------VAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ 229
Query: 241 CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ 300
CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ
Sbjct: 230 CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ 289
Query: 301 YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL 360
YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL
Sbjct: 290 YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL 349
Query: 361 SVSYNRSYQINEHYPCITPCFER 383
SVSYNRSYQINEHYPCITPCFER
Sbjct: 350 SVSYNRSYQINEHYPCITPCFER 372
>gi|197276676 cyclin J isoform 3 [Homo sapiens]
Length = 371
Score = 751 bits (1940), Expect = 0.0
Identities = 371/383 (96%), Positives = 371/383 (96%), Gaps = 12/383 (3%)
Query: 1 MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA 60
MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA
Sbjct: 1 MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA 60
Query: 61 RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL
Sbjct: 61 RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
Query: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180
VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM
Sbjct: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180
Query: 181 AKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ 240
AKYADYFLEVSLQ AAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ
Sbjct: 181 AKYADYFLEVSLQ------------AAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ 228
Query: 241 CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ 300
CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ
Sbjct: 229 CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ 288
Query: 301 YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL 360
YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL
Sbjct: 289 YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL 348
Query: 361 SVSYNRSYQINEHYPCITPCFER 383
SVSYNRSYQINEHYPCITPCFER
Sbjct: 349 SVSYNRSYQINEHYPCITPCFER 371
>gi|94680985 cyclin J-like [Homo sapiens]
Length = 435
Score = 285 bits (730), Expect = 4e-77
Identities = 173/442 (39%), Positives = 240/442 (54%), Gaps = 69/442 (15%)
Query: 3 LEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSARH 62
++ WW G++A+D+H LR KELKLP+++ SP L RR+F D++ ++S+ LCP+ARH
Sbjct: 2 MDEPWWEGRVASDVHCTLREKELKLPTFRAHSPLLKSRRFFVDILTLLSSHCQLCPAARH 61
Query: 63 LAVYLLDLFMDRYDISI-QQLHLVALSCLLLAS--------------------------- 94
LAVYLLD FMDRY+++ +QL+ VA+SCLLLA+
Sbjct: 62 LAVYLLDHFMDRYNVTTSKQLYTVAVSCLLLANGVSLLSPRLKCSGMISAHCNLHLPGSS 121
Query: 95 ---------------------KFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELL 133
KFE++ED VPKLEQ+NS +++ N LTK+ LL ELL
Sbjct: 122 NSPASAPHPPPTPPQVAETTGKFEDREDHVPKLEQINSTRILSSQNFTLTKKELLSTELL 181
Query: 134 LLETFQWNLCLPTAAHFIEYYLSEAVHETDLH-DGWPMICLEKTKLYMAKYADYFLEVSL 192
LLE F WNLCLPT AHF++YYL +V + D H WP C KTK + +YA YFLEV+L
Sbjct: 182 LLEAFSWNLCLPTPAHFLDYYLLASVSQKDHHCHTWPTTCPRKTKECLKEYAHYFLEVTL 241
Query: 193 QDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIAHDND 252
QD+ F + PS+VAAACV +SRI L+LSP W L R+++YS + L CIE LL+ +DN
Sbjct: 242 QDHIFYKFQPSVVAAACVGASRICLQLSPYWTRDLQRISSYSLEHLSTCIEILLVVYDNV 301
Query: 253 VKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQY--LHQTHQTSLQYRHPTSEQPS 310
+K+A + QA L++ V FQ P Y L Q T Q++ P +
Sbjct: 302 LKDAVAVKSQA------LAMVPGTPPTPTQVLFQPPAYPALGQPATTLAQFQTPVQDLCL 355
Query: 311 CQQIVSTTHTSSYTLQ-TCPAGFQTSVQGLGHMQ-------TGVGMSLAIPVEVKPCLSV 362
+ H S L + + T Q L + + M +AI E + CL+
Sbjct: 356 AYRDSLQAHRSGSLLSGSTGSSLHTPYQPLQPLDMCPVPVPASLSMHMAIAAEPRHCLAT 415
Query: 363 SYNRSYQINEH-YPCITPCFER 383
+Y SY H +P T CF+R
Sbjct: 416 TYGSSYFSGSHMFP--TGCFDR 435
>gi|161377472 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 77.8 bits (190), Expect = 2e-14
Identities = 72/243 (29%), Positives = 111/243 (45%), Gaps = 34/243 (13%)
Query: 11 QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65
+ A +I+Q LR E++ Y + P ++ +R D + V + L +LAV
Sbjct: 166 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 225
Query: 66 YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125
LD F+ + +L LV + +LLASK+EE P++++ + T TK+
Sbjct: 226 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 278
Query: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYAD 185
LL ME LLL+ ++L +PT F+ YL +C+ L A
Sbjct: 279 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR-----------QGVCVRTENL-----AK 322
Query: 186 YFLEVSLQDY-AFLNYAPSLVAAA--CVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCI 242
Y E+SL + FL Y PSL+AAA C+A+ + WP L T YS +V C+
Sbjct: 323 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCL 379
Query: 243 ERL 245
L
Sbjct: 380 SEL 382
>gi|161377470 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 77.8 bits (190), Expect = 2e-14
Identities = 72/243 (29%), Positives = 111/243 (45%), Gaps = 34/243 (13%)
Query: 11 QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65
+ A +I+Q LR E++ Y + P ++ +R D + V + L +LAV
Sbjct: 166 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 225
Query: 66 YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125
LD F+ + +L LV + +LLASK+EE P++++ + T TK+
Sbjct: 226 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 278
Query: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYAD 185
LL ME LLL+ ++L +PT F+ YL +C+ L A
Sbjct: 279 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR-----------QGVCVRTENL-----AK 322
Query: 186 YFLEVSLQDY-AFLNYAPSLVAAA--CVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCI 242
Y E+SL + FL Y PSL+AAA C+A+ + WP L T YS +V C+
Sbjct: 323 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCL 379
Query: 243 ERL 245
L
Sbjct: 380 SEL 382
>gi|161377468 cyclin A1 isoform b [Homo sapiens]
Length = 464
Score = 77.8 bits (190), Expect = 2e-14
Identities = 72/243 (29%), Positives = 111/243 (45%), Gaps = 34/243 (13%)
Query: 11 QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65
+ A +I+Q LR E++ Y + P ++ +R D + V + L +LAV
Sbjct: 209 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 268
Query: 66 YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125
LD F+ + +L LV + +LLASK+EE P++++ + T TK+
Sbjct: 269 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 321
Query: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYAD 185
LL ME LLL+ ++L +PT F+ YL +C+ L A
Sbjct: 322 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR-----------QGVCVRTENL-----AK 365
Query: 186 YFLEVSLQDY-AFLNYAPSLVAAA--CVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCI 242
Y E+SL + FL Y PSL+AAA C+A+ + WP L T YS +V C+
Sbjct: 366 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCL 422
Query: 243 ERL 245
L
Sbjct: 423 SEL 425
>gi|4502611 cyclin A1 isoform a [Homo sapiens]
Length = 465
Score = 77.8 bits (190), Expect = 2e-14
Identities = 72/243 (29%), Positives = 111/243 (45%), Gaps = 34/243 (13%)
Query: 11 QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65
+ A +I+Q LR E++ Y + P ++ +R D + V + L +LAV
Sbjct: 210 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 269
Query: 66 YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125
LD F+ + +L LV + +LLASK+EE P++++ + T TK+
Sbjct: 270 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 322
Query: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYAD 185
LL ME LLL+ ++L +PT F+ YL +C+ L A
Sbjct: 323 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR-----------QGVCVRTENL-----AK 366
Query: 186 YFLEVSLQDY-AFLNYAPSLVAAA--CVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCI 242
Y E+SL + FL Y PSL+AAA C+A+ + WP L T YS +V C+
Sbjct: 367 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCL 423
Query: 243 ERL 245
L
Sbjct: 424 SEL 426
>gi|4502613 cyclin A [Homo sapiens]
Length = 432
Score = 71.2 bits (173), Expect = 1e-12
Identities = 74/264 (28%), Positives = 113/264 (42%), Gaps = 41/264 (15%)
Query: 15 DIHQALRYKELKLP---SYKGQSPQL--SLRRYFADLIAIVSNRFTLCPSARHLAVYLLD 69
DIH LR E+K Y + P + S+R D + V + L HLAV +D
Sbjct: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240
Query: 70 LFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLH 129
F+ + +L LV + +LLASKFEE P++ + + T TK+ +L
Sbjct: 241 RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYP--PEVAEFVYITDDT-----YTKKQVLR 293
Query: 130 MELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLE 189
ME L+L+ ++L PT F+ Y LH +E +++ E
Sbjct: 294 MEHLVLKVLTFDLAAPTVNQFLTQYF--------LHQQPANCKVESLAMFLG-------E 338
Query: 190 VSLQDY-AFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIA 248
+SL D +L Y PS++A A + + +WP L R T Y+ + L C L+
Sbjct: 339 LSLIDADPYLKYLPSVIAGAAFHLA-LYTVTGQSWPESLIRKTGYTLESLKPC---LMDL 394
Query: 249 HDNDVKEANKQRGQAGPQSAQLSV 272
H +K PQ AQ S+
Sbjct: 395 HQTYLK---------APQHAQQSI 409
>gi|4757930 cyclin B2 [Homo sapiens]
Length = 398
Score = 65.9 bits (159), Expect = 6e-11
Identities = 61/247 (24%), Positives = 108/247 (43%), Gaps = 32/247 (12%)
Query: 7 WWRGQLAAD----IHQALRYKELKL---PSY-KGQSPQLSLRRYFADLIAIVSNRFTLCP 58
W QL +D I+Q LR E+ P + G+ +R D + V ++F L
Sbjct: 125 WENPQLCSDYVKDIYQYLRQLEVLQSINPHFLDGRDINGRMRAILVDWLVQVHSKFRLLQ 184
Query: 59 SARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNM 118
++ V ++D F+ +S ++L LV ++ LLLASK+EE P +E +
Sbjct: 185 ETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFS--PNIEDFVYI-----T 237
Query: 119 NLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKL 178
+ T + ME L+L+ ++ L P HF+ + + H
Sbjct: 238 DNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQH------------- 284
Query: 179 YMAKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFL 238
A Y +E++L DY ++Y PS VAAA S+ +L W + T Y+ + +
Sbjct: 285 ---TLAKYLMELTLIDYDMVHYHPSKVAAAASCLSQKVLG-QGKWNLKQQYYTGYTENEV 340
Query: 239 VQCIERL 245
++ ++ +
Sbjct: 341 LEVMQHM 347
>gi|16950655 cyclin D1 [Homo sapiens]
Length = 295
Score = 64.3 bits (155), Expect = 2e-10
Identities = 59/205 (28%), Positives = 100/205 (48%), Gaps = 29/205 (14%)
Query: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVP-KLEQLNSLGCMTNMNLV 121
LA+ LD F+ + +L L+ +C+ +ASK +E ++P E+L C+ N +
Sbjct: 80 LAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKE---TIPLTAEKL----CIYTDNSI 132
Query: 122 LTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMA 181
++ LL MELLL+ +WNL T FIE++LS+ M E+ K +
Sbjct: 133 RPEE-LLQMELLLVNKLKWNLAAMTPHDFIEHFLSK------------MPEAEENKQIIR 179
Query: 182 KYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRL-SPTWPTRLHRLTAY------- 233
K+A F+ + D F++ PS+VAA V ++ L L SP +RLT +
Sbjct: 180 KHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKC 239
Query: 234 SWDFLVQCIERLLIAHDNDVKEANK 258
D L C E++ ++ +++A +
Sbjct: 240 DPDCLRACQEQIEALLESSLRQAQQ 264
>gi|153791755 cyclin domain containing [Homo sapiens]
Length = 350
Score = 61.6 bits (148), Expect = 1e-09
Identities = 50/178 (28%), Positives = 83/178 (46%), Gaps = 15/178 (8%)
Query: 50 VSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQL 109
V +F L + L V LD F+ ++ L+ ++ LL+A K + E P+++QL
Sbjct: 143 VHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACK--QVEVHPPRVKQL 200
Query: 110 NSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWP 169
+L C ++Q L ++E ++L + L PT + F+E++ V
Sbjct: 201 LALCCGA-----FSRQQLCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAE---- 251
Query: 170 MICLEKTKLYMAKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRL 227
L A E+SL DYAF +Y+PSL+A C+A + +LR+S RL
Sbjct: 252 ----ASEALEAQALARGVAELSLADYAFTSYSPSLLAICCLALADRMLRVSRPVDLRL 305
>gi|14327896 cyclin B1 [Homo sapiens]
Length = 433
Score = 57.8 bits (138), Expect = 2e-08
Identities = 55/235 (23%), Positives = 100/235 (42%), Gaps = 28/235 (11%)
Query: 15 DIHQALRYKELKL---PSYK-GQSPQLSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDL 70
DI+ LR E + P Y G+ ++R D + V +F L ++ V ++D
Sbjct: 173 DIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDR 232
Query: 71 FMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHM 130
FM + + L LV ++ + +ASK+EE ++ +T+ TK + M
Sbjct: 233 FMQNNCVPKKMLQLVGVTAMFIASKYEEMYP-----PEIGDFAFVTDN--TYTKHQIRQM 285
Query: 131 ELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEV 190
E+ +L + L P HF+ + + E D+ A Y +E+
Sbjct: 286 EMKILRALNFGLGRPLPLHFLR--RASKIGEVDVE--------------QHTLAKYLMEL 329
Query: 191 SLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERL 245
++ DY +++ PS +AA + IL PT H L +Y+ + L+ ++ L
Sbjct: 330 TMLDYDMVHFPPSQIAAGAFCLALKILDNGEWTPTLQHYL-SYTEESLLPVMQHL 383
>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
Length = 292
Score = 55.5 bits (132), Expect = 8e-08
Identities = 58/224 (25%), Positives = 94/224 (41%), Gaps = 23/224 (10%)
Query: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVL 122
LA+ LD ++ QL L+ C+LLASK +E + +E+L C+ + V
Sbjct: 80 LAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKL--RETTPLTIEKL----CIYTDHAVS 133
Query: 123 TKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAK 182
+Q L E+L+L +W+L A F+ + L D + + K
Sbjct: 134 PRQ-LRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRD------------RQALVKK 180
Query: 183 YADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRL----TAYSWDFL 238
+A FL + DY F Y PS++A + ++ L L L T D L
Sbjct: 181 HAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCL 240
Query: 239 VQCIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRP 282
C E++ A ++EA++ P++ + S Q SQ S P
Sbjct: 241 RACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTP 284
>gi|5802992 cyclin I [Homo sapiens]
Length = 377
Score = 54.3 bits (129), Expect = 2e-07
Identities = 54/204 (26%), Positives = 89/204 (43%), Gaps = 24/204 (11%)
Query: 26 KLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLV 85
K+PS + SP S R +A + +F L P LA LLD F+ + L +
Sbjct: 33 KMPSNQNVSP--SQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCI 90
Query: 86 ALSCLLLASKFEEKEDSVPKLEQL---NSLGCMTNMNLVLTKQNLLHMELLLLETFQWNL 142
A+SC LA+K E+++ +P L+ L + GC + +L ME ++L+ W+L
Sbjct: 91 AISCFFLAAKTVEEDERIPVLKVLARDSFCGC--------SSSEILRMERIILDKLNWDL 142
Query: 143 CLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEVSLQDYA---FLN 199
T F+ + + AV P + KL +++ + L A L
Sbjct: 143 HTATPLDFLHIFHAIAVSTR------PQLLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQ 196
Query: 200 YAPSLVAAACVASSRIILRLSPTW 223
+ S++A A V S + +L P W
Sbjct: 197 FRGSMLALAMV--SLEMEKLIPDW 218
>gi|4502617 cyclin D2 [Homo sapiens]
Length = 289
Score = 53.9 bits (128), Expect = 2e-07
Identities = 46/151 (30%), Positives = 68/151 (45%), Gaps = 19/151 (12%)
Query: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVL 122
LA+ LD F+ L L+ C+ LASK KE S E+L C+ N +
Sbjct: 79 LAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKL--KETSPLTAEKL----CIYTDNSI- 131
Query: 123 TKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAK 182
Q LL EL++L +WNL T FIE+ L + + EK L + K
Sbjct: 132 KPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQR-----------EKLSL-IRK 179
Query: 183 YADYFLEVSLQDYAFLNYAPSLVAAACVASS 213
+A F+ + D+ F Y PS++A V ++
Sbjct: 180 HAQTFIALCATDFKFAMYPPSMIATGSVGAA 210
>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
Length = 1395
Score = 53.9 bits (128), Expect = 2e-07
Identities = 50/227 (22%), Positives = 100/227 (44%), Gaps = 26/227 (11%)
Query: 21 RYKELKLPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDIS 78
R ++ L Y + +++ +R D + V F + +LAV L+DL++ +
Sbjct: 1140 REEQFILTDYMNRQIEITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVDLYLMKAVCK 1199
Query: 79 IQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETF 138
+L L+ + ++A+KFEE P+++ + C N + +L ME+ +L
Sbjct: 1200 KDKLQLLGATAFMIAAKFEEHNS--PRVDDFVYI-CDDNYQ----RSEVLSMEINILNVL 1252
Query: 139 QWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEVSLQDYAFL 198
+ ++ +P A HF+ Y + +H T + + Y E++LQ+Y ++
Sbjct: 1253 KCDINIPIAYHFLRRY-ARCIH---------------TNMKTLTLSRYICEMTLQEYHYV 1296
Query: 199 NYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERL 245
S +AAA + + + +L W L + YS L + +L
Sbjct: 1297 QEKASKLAAASLLLALYMKKLG-YWVPFLEHYSGYSISELHPLVRQL 1342
>gi|209862835 cyclin D3 isoform 1 [Homo sapiens]
Length = 211
Score = 53.5 bits (127), Expect = 3e-07
Identities = 58/220 (26%), Positives = 94/220 (42%), Gaps = 27/220 (12%)
Query: 71 FMDRYDISIQ----QLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQN 126
++DRY + QL L+ C+LLASK +E + +E+L C+ + V +Q
Sbjct: 3 YLDRYLSCVPTRKAQLQLLGAVCMLLASKL--RETTPLTIEKL----CIYTDHAVSPRQ- 55
Query: 127 LLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADY 186
L E+L+L +W+L A F+ + L H L + + K+A
Sbjct: 56 LRDWEVLVLGKLKWDLAAVIAHDFLAFIL----HRLSLP--------RDRQALVKKHAQT 103
Query: 187 FLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRL----TAYSWDFLVQCI 242
FL + DY F Y PS++A + ++ L L L T D L C
Sbjct: 104 FLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQ 163
Query: 243 ERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRP 282
E++ A ++EA++ P++ + S Q SQ S P
Sbjct: 164 EQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTP 203
>gi|16306525 cyclin B3 isoform 1 [Homo sapiens]
Length = 291
Score = 52.4 bits (124), Expect = 7e-07
Identities = 53/223 (23%), Positives = 97/223 (43%), Gaps = 32/223 (14%)
Query: 28 PSYKGQSPQ-----LSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQL 82
PS +SP L R F DL + F + +LAV L+DL++ + +L
Sbjct: 43 PSSLQESPSSLQGALKKRSAFEDLTNV---SFEMTHETLYLAVKLVDLYLMKAVCKKDKL 99
Query: 83 HLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNL 142
L+ + ++A+KFEE P+++ + C N + +L ME+ +L + ++
Sbjct: 100 QLLGATAFMIAAKFEEHNS--PRVDDFVYI-CDDNYQ----RSEVLSMEINILNVLKCDI 152
Query: 143 CLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEVSLQDYAFLNYAP 202
+P A HF+ Y + +H T + + Y E++LQ+Y ++
Sbjct: 153 NIPIAYHFLRRY-ARCIH---------------TNMKTLTLSRYICEMTLQEYHYVQEKA 196
Query: 203 SLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERL 245
S +AAA + + + +L W L + YS L + +L
Sbjct: 197 SKLAAASLLLALYMKKLG-YWVPFLEHYSGYSISELHPLVRQL 238
>gi|17318565 cyclin E2 [Homo sapiens]
Length = 404
Score = 49.3 bits (116), Expect = 6e-06
Identities = 49/210 (23%), Positives = 93/210 (44%), Gaps = 29/210 (13%)
Query: 39 LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFM-DRYDISIQQLHLVALSCLLLASKFE 97
+R D + V +TL +LA D FM + DI+ L L+ ++ L +ASK E
Sbjct: 141 MRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLE 200
Query: 98 EKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSE 157
E PKL++ + + +++++L MEL++L+ +W LC T ++ +L
Sbjct: 201 EIY--APKLQEFAYV-----TDGACSEEDILRMELIILKALKWELCPVTIISWLNLFL-- 251
Query: 158 AVHETDLHDGWPMICL----EKTKLYMAKYADYFLEVSLQDYAFLNYAPSLVAAACVASS 213
+ D P + L ++T + +A+ D L + D Y AA C +S
Sbjct: 252 ---QVDALKDAPKVLLPQYSQETFIQIAQLLD--LCILAIDSLEFQYRILTAAALCHFTS 306
Query: 214 RIILRLSPTWPTRLHRLTAYSWDFLVQCIE 243
+++ + + WD + +C++
Sbjct: 307 IEVVK----------KASGLEWDSISECVD 326
>gi|40805832 cyclin G1 [Homo sapiens]
Length = 295
Score = 48.9 bits (115), Expect = 8e-06
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
Query: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVL 122
LAV LLD F+ + + + L V LSC LA K E+E +VP L +
Sbjct: 75 LAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRIS-----QYRF 129
Query: 123 TKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLS 156
T +L+ ME ++LE W + TA F++ Y S
Sbjct: 130 TVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYS 163
>gi|4757934 cyclin G1 [Homo sapiens]
Length = 295
Score = 48.9 bits (115), Expect = 8e-06
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
Query: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVL 122
LAV LLD F+ + + + L V LSC LA K E+E +VP L +
Sbjct: 75 LAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRIS-----QYRF 129
Query: 123 TKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLS 156
T +L+ ME ++LE W + TA F++ Y S
Sbjct: 130 TVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYS 163
>gi|118572588 cyclin F [Homo sapiens]
Length = 786
Score = 48.5 bits (114), Expect = 1e-05
Identities = 41/196 (20%), Positives = 88/196 (44%), Gaps = 26/196 (13%)
Query: 47 IAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKL 106
+A + + +LC HL V +D ++ R + +L L+ ++C+++ ++F KE +
Sbjct: 320 VATMKDFTSLC---LHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKE-----I 371
Query: 107 EQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHD 166
+ +T+ ++L+ M ++ + + +PT + E L+
Sbjct: 372 LTIREAVWLTDNTYKY--EDLVRMMGEIVSALEGKIRVPTVVDYKEVLLT---------- 419
Query: 167 GWPMICLEKTKLYMAKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTR 226
L +L + E+SL + YAP+ +AAA + +R+ + W T+
Sbjct: 420 ------LVPVELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQ 473
Query: 227 LHRLTAYSWDFLVQCI 242
L LT +S++ L+ C+
Sbjct: 474 LWDLTGFSYEDLIPCV 489
>gi|89886237 cyclin I family, member 2 [Homo sapiens]
Length = 369
Score = 42.7 bits (99), Expect = 5e-04
Identities = 28/128 (21%), Positives = 58/128 (45%), Gaps = 8/128 (6%)
Query: 30 YKGQSPQLSLRRYFADLIAIV---SNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVA 86
++G PQ + F +++ + N F S +LA+ + + + + LH
Sbjct: 137 WRGGKPQDEICDAFEEVVLWLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCAT 196
Query: 87 LSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPT 146
++ L LA+K E+E+ +P+++ + + LL MEL +L+ W+L + T
Sbjct: 197 ITSLRLAAKVNEEEEFIPQVKDFTK-----HYGSDYSPNELLRMELAILDRLHWDLYIGT 251
Query: 147 AAHFIEYY 154
F+ +
Sbjct: 252 PLDFLTIF 259
>gi|209915553 cyclin D3 isoform 3 [Homo sapiens]
Length = 220
Score = 42.0 bits (97), Expect = 0.001
Identities = 41/170 (24%), Positives = 67/170 (39%), Gaps = 16/170 (9%)
Query: 117 NMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKT 176
+M +L L E+L+L +W+L A F+ + L D
Sbjct: 55 HMRKMLAYWMLEDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRD------------R 102
Query: 177 KLYMAKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRL----TA 232
+ + K+A FL + DY F Y PS++A + ++ L L L T
Sbjct: 103 QALVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITG 162
Query: 233 YSWDFLVQCIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRP 282
D L C E++ A ++EA++ P++ + S Q SQ S P
Sbjct: 163 TEVDCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTP 212
>gi|17318559 cyclin E1 isoform 1 [Homo sapiens]
Length = 410
Score = 38.9 bits (89), Expect = 0.008
Identities = 40/186 (21%), Positives = 81/186 (43%), Gaps = 31/186 (16%)
Query: 66 YLLDLFMDRYDISIQQ-----LHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
YL F DRY + + L L+ +S L +A+K EE PKL Q + +
Sbjct: 167 YLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYP--PKLHQFAYV-----TDG 219
Query: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180
+ +L MEL++++ +W L T ++ Y+ + + DLH+ + L + +
Sbjct: 220 ACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYM-QVAYLNDLHE----VLLPQYPQQI 274
Query: 181 AKYADYFLEVSLQDYAFLNYAPSLVAAACV---ASSRIILRLSPTWPTRLHRLTAYSWDF 237
L++ + D L + ++AA+ + +SS + + +++ Y W
Sbjct: 275 FIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSEL-----------MQKVSGYQWCD 323
Query: 238 LVQCIE 243
+ C++
Sbjct: 324 IENCVK 329
>gi|17318561 cyclin E1 isoform 2 [Homo sapiens]
Length = 395
Score = 38.9 bits (89), Expect = 0.008
Identities = 40/186 (21%), Positives = 81/186 (43%), Gaps = 31/186 (16%)
Query: 66 YLLDLFMDRYDISIQQ-----LHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
YL F DRY + + L L+ +S L +A+K EE PKL Q + +
Sbjct: 152 YLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYP--PKLHQFAYV-----TDG 204
Query: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180
+ +L MEL++++ +W L T ++ Y+ + + DLH+ + L + +
Sbjct: 205 ACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYM-QVAYLNDLHE----VLLPQYPQQI 259
Query: 181 AKYADYFLEVSLQDYAFLNYAPSLVAAACV---ASSRIILRLSPTWPTRLHRLTAYSWDF 237
L++ + D L + ++AA+ + +SS + + +++ Y W
Sbjct: 260 FIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSEL-----------MQKVSGYQWCD 308
Query: 238 LVQCIE 243
+ C++
Sbjct: 309 IENCVK 314
>gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo
sapiens]
Length = 307
Score = 38.5 bits (88), Expect = 0.010
Identities = 41/185 (22%), Positives = 73/185 (39%), Gaps = 35/185 (18%)
Query: 39 LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEE 98
+R D + V L +LAV+LLD ++ + + +L L+ ++CL +A K EE
Sbjct: 107 MRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEE 166
Query: 99 KEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEA 158
P + C+ + + ++ LL E +L +
Sbjct: 167 CVLPEP------AFLCLLSAD-SFSRAELLRAERRILSRLDFR----------------- 202
Query: 159 VHETDLHDGWPMIC------LEKTKLYMAKYADYFLEVSLQDYAFLNYAPSLVAAACVAS 212
LH P++C L + + A YFLE+SL + + P AAA ++
Sbjct: 203 -----LHHPGPLLCLGLLAALAGSSPQVMLLATYFLELSLLEAEAAGWEPGRRAAAALSL 257
Query: 213 SRIIL 217
+ +L
Sbjct: 258 AHRLL 262
>gi|4757936 cyclin G2 [Homo sapiens]
Length = 344
Score = 37.7 bits (86), Expect = 0.017
Identities = 26/116 (22%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 39 LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEE 98
LR + + ++N F C LAV +LD F+ + + L + + LLA++ E
Sbjct: 55 LRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVE 114
Query: 99 KEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYY 154
++ ++P + + T ++ ME ++ E + L TA +F+ Y
Sbjct: 115 EDCNIPSTHDVIRIS-----QCKCTASDIKRMEKIISEKLHYELEATTALNFLHLY 165
>gi|4502623 cyclin H [Homo sapiens]
Length = 323
Score = 37.7 bits (86), Expect = 0.017
Identities = 37/140 (26%), Positives = 64/140 (45%), Gaps = 18/140 (12%)
Query: 78 SIQQLH--LVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTK--QNLLHMELL 133
S+ + H ++ L+C LA K +E S P+ +G + L K + +L ELL
Sbjct: 95 SVMEYHPRIIMLTCAFLACKVDEFNVSSPQF-----VGNLRESPLGQEKALEQILEYELL 149
Query: 134 LLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEVSLQ 193
L++ ++L + E +L DL +P+ LE ++ D+ ++L
Sbjct: 150 LIQQLNFHLIVHNPYRPFEGFL------IDLKTRYPI--LENPEILRKTADDFLNRIALT 201
Query: 194 DYAFLNYAPSLVAAACVASS 213
D A+L Y PS +A + SS
Sbjct: 202 D-AYLLYTPSQIALTAILSS 220
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.133 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,225,123
Number of Sequences: 37866
Number of extensions: 596800
Number of successful extensions: 1621
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 1548
Number of HSP's gapped (non-prelim): 53
length of query: 383
length of database: 18,247,518
effective HSP length: 104
effective length of query: 279
effective length of database: 14,309,454
effective search space: 3992337666
effective search space used: 3992337666
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.