Guide to the Human Genome
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Search of human proteins with 197276674

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|197276674 cyclin J isoform 1 [Homo sapiens]
         (383 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|197276674 cyclin J isoform 1 [Homo sapiens]                        785   0.0  
gi|40254889 cyclin J isoform 2 [Homo sapiens]                         753   0.0  
gi|197276676 cyclin J isoform 3 [Homo sapiens]                        751   0.0  
gi|94680985 cyclin J-like [Homo sapiens]                              285   4e-77
gi|161377472 cyclin A1 isoform c [Homo sapiens]                        78   2e-14
gi|161377470 cyclin A1 isoform c [Homo sapiens]                        78   2e-14
gi|161377468 cyclin A1 isoform b [Homo sapiens]                        78   2e-14
gi|4502611 cyclin A1 isoform a [Homo sapiens]                          78   2e-14
gi|4502613 cyclin A [Homo sapiens]                                     71   1e-12
gi|4757930 cyclin B2 [Homo sapiens]                                    66   6e-11
gi|16950655 cyclin D1 [Homo sapiens]                                   64   2e-10
gi|153791755 cyclin domain containing [Homo sapiens]                   62   1e-09
gi|14327896 cyclin B1 [Homo sapiens]                                   58   2e-08
gi|4502619 cyclin D3 isoform 2 [Homo sapiens]                          55   8e-08
gi|5802992 cyclin I [Homo sapiens]                                     54   2e-07
gi|4502617 cyclin D2 [Homo sapiens]                                    54   2e-07
gi|90669307 cyclin B3 isoform 3 [Homo sapiens]                         54   2e-07
gi|209862835 cyclin D3 isoform 1 [Homo sapiens]                        54   3e-07
gi|16306525 cyclin B3 isoform 1 [Homo sapiens]                         52   7e-07
gi|17318565 cyclin E2 [Homo sapiens]                                   49   6e-06
gi|40805832 cyclin G1 [Homo sapiens]                                   49   8e-06
gi|4757934 cyclin G1 [Homo sapiens]                                    49   8e-06
gi|118572588 cyclin F [Homo sapiens]                                   49   1e-05
gi|89886237 cyclin I family, member 2 [Homo sapiens]                   43   5e-04
gi|209915553 cyclin D3 isoform 3 [Homo sapiens]                        42   0.001
gi|17318559 cyclin E1 isoform 1 [Homo sapiens]                         39   0.008
gi|17318561 cyclin E1 isoform 2 [Homo sapiens]                         39   0.008
gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho...    39   0.010
gi|4757936 cyclin G2 [Homo sapiens]                                    38   0.017
gi|4502623 cyclin H [Homo sapiens]                                     38   0.017

>gi|197276674 cyclin J isoform 1 [Homo sapiens]
          Length = 383

 Score =  785 bits (2026), Expect = 0.0
 Identities = 383/383 (100%), Positives = 383/383 (100%)

Query: 1   MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA 60
           MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA
Sbjct: 1   MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA 60

Query: 61  RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
           RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL
Sbjct: 61  RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120

Query: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180
           VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM
Sbjct: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180

Query: 181 AKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ 240
           AKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ
Sbjct: 181 AKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ 240

Query: 241 CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ 300
           CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ
Sbjct: 241 CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ 300

Query: 301 YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL 360
           YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL
Sbjct: 301 YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL 360

Query: 361 SVSYNRSYQINEHYPCITPCFER 383
           SVSYNRSYQINEHYPCITPCFER
Sbjct: 361 SVSYNRSYQINEHYPCITPCFER 383


>gi|40254889 cyclin J isoform 2 [Homo sapiens]
          Length = 372

 Score =  753 bits (1945), Expect = 0.0
 Identities = 372/383 (97%), Positives = 372/383 (97%), Gaps = 11/383 (2%)

Query: 1   MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA 60
           MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA
Sbjct: 1   MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA 60

Query: 61  RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
           RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL
Sbjct: 61  RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120

Query: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180
           VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM
Sbjct: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180

Query: 181 AKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ 240
           AKYADYFLEVSLQ           VAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ
Sbjct: 181 AKYADYFLEVSLQ-----------VAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ 229

Query: 241 CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ 300
           CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ
Sbjct: 230 CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ 289

Query: 301 YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL 360
           YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL
Sbjct: 290 YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL 349

Query: 361 SVSYNRSYQINEHYPCITPCFER 383
           SVSYNRSYQINEHYPCITPCFER
Sbjct: 350 SVSYNRSYQINEHYPCITPCFER 372


>gi|197276676 cyclin J isoform 3 [Homo sapiens]
          Length = 371

 Score =  751 bits (1940), Expect = 0.0
 Identities = 371/383 (96%), Positives = 371/383 (96%), Gaps = 12/383 (3%)

Query: 1   MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA 60
           MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA
Sbjct: 1   MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSA 60

Query: 61  RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
           RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL
Sbjct: 61  RHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120

Query: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180
           VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM
Sbjct: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180

Query: 181 AKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ 240
           AKYADYFLEVSLQ            AAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ
Sbjct: 181 AKYADYFLEVSLQ------------AAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQ 228

Query: 241 CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ 300
           CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ
Sbjct: 229 CIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQ 288

Query: 301 YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL 360
           YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL
Sbjct: 289 YRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCL 348

Query: 361 SVSYNRSYQINEHYPCITPCFER 383
           SVSYNRSYQINEHYPCITPCFER
Sbjct: 349 SVSYNRSYQINEHYPCITPCFER 371


>gi|94680985 cyclin J-like [Homo sapiens]
          Length = 435

 Score =  285 bits (730), Expect = 4e-77
 Identities = 173/442 (39%), Positives = 240/442 (54%), Gaps = 69/442 (15%)

Query: 3   LEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSARH 62
           ++  WW G++A+D+H  LR KELKLP+++  SP L  RR+F D++ ++S+   LCP+ARH
Sbjct: 2   MDEPWWEGRVASDVHCTLREKELKLPTFRAHSPLLKSRRFFVDILTLLSSHCQLCPAARH 61

Query: 63  LAVYLLDLFMDRYDISI-QQLHLVALSCLLLAS--------------------------- 94
           LAVYLLD FMDRY+++  +QL+ VA+SCLLLA+                           
Sbjct: 62  LAVYLLDHFMDRYNVTTSKQLYTVAVSCLLLANGVSLLSPRLKCSGMISAHCNLHLPGSS 121

Query: 95  ---------------------KFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELL 133
                                KFE++ED VPKLEQ+NS   +++ N  LTK+ LL  ELL
Sbjct: 122 NSPASAPHPPPTPPQVAETTGKFEDREDHVPKLEQINSTRILSSQNFTLTKKELLSTELL 181

Query: 134 LLETFQWNLCLPTAAHFIEYYLSEAVHETDLH-DGWPMICLEKTKLYMAKYADYFLEVSL 192
           LLE F WNLCLPT AHF++YYL  +V + D H   WP  C  KTK  + +YA YFLEV+L
Sbjct: 182 LLEAFSWNLCLPTPAHFLDYYLLASVSQKDHHCHTWPTTCPRKTKECLKEYAHYFLEVTL 241

Query: 193 QDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIAHDND 252
           QD+ F  + PS+VAAACV +SRI L+LSP W   L R+++YS + L  CIE LL+ +DN 
Sbjct: 242 QDHIFYKFQPSVVAAACVGASRICLQLSPYWTRDLQRISSYSLEHLSTCIEILLVVYDNV 301

Query: 253 VKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQY--LHQTHQTSLQYRHPTSEQPS 310
           +K+A   + QA      L++          V FQ P Y  L Q   T  Q++ P  +   
Sbjct: 302 LKDAVAVKSQA------LAMVPGTPPTPTQVLFQPPAYPALGQPATTLAQFQTPVQDLCL 355

Query: 311 CQQIVSTTHTSSYTLQ-TCPAGFQTSVQGLGHMQ-------TGVGMSLAIPVEVKPCLSV 362
             +     H S   L  +  +   T  Q L  +          + M +AI  E + CL+ 
Sbjct: 356 AYRDSLQAHRSGSLLSGSTGSSLHTPYQPLQPLDMCPVPVPASLSMHMAIAAEPRHCLAT 415

Query: 363 SYNRSYQINEH-YPCITPCFER 383
           +Y  SY    H +P  T CF+R
Sbjct: 416 TYGSSYFSGSHMFP--TGCFDR 435


>gi|161377472 cyclin A1 isoform c [Homo sapiens]
          Length = 421

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 72/243 (29%), Positives = 111/243 (45%), Gaps = 34/243 (13%)

Query: 11  QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65
           + A +I+Q LR  E++      Y  + P ++  +R    D +  V   + L     +LAV
Sbjct: 166 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 225

Query: 66  YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125
             LD F+    +   +L LV  + +LLASK+EE     P++++   +   T      TK+
Sbjct: 226 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 278

Query: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYAD 185
            LL ME LLL+   ++L +PT   F+  YL               +C+    L     A 
Sbjct: 279 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR-----------QGVCVRTENL-----AK 322

Query: 186 YFLEVSLQDY-AFLNYAPSLVAAA--CVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCI 242
           Y  E+SL +   FL Y PSL+AAA  C+A+  +       WP  L   T YS   +V C+
Sbjct: 323 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCL 379

Query: 243 ERL 245
             L
Sbjct: 380 SEL 382


>gi|161377470 cyclin A1 isoform c [Homo sapiens]
          Length = 421

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 72/243 (29%), Positives = 111/243 (45%), Gaps = 34/243 (13%)

Query: 11  QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65
           + A +I+Q LR  E++      Y  + P ++  +R    D +  V   + L     +LAV
Sbjct: 166 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 225

Query: 66  YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125
             LD F+    +   +L LV  + +LLASK+EE     P++++   +   T      TK+
Sbjct: 226 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 278

Query: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYAD 185
            LL ME LLL+   ++L +PT   F+  YL               +C+    L     A 
Sbjct: 279 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR-----------QGVCVRTENL-----AK 322

Query: 186 YFLEVSLQDY-AFLNYAPSLVAAA--CVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCI 242
           Y  E+SL +   FL Y PSL+AAA  C+A+  +       WP  L   T YS   +V C+
Sbjct: 323 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCL 379

Query: 243 ERL 245
             L
Sbjct: 380 SEL 382


>gi|161377468 cyclin A1 isoform b [Homo sapiens]
          Length = 464

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 72/243 (29%), Positives = 111/243 (45%), Gaps = 34/243 (13%)

Query: 11  QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65
           + A +I+Q LR  E++      Y  + P ++  +R    D +  V   + L     +LAV
Sbjct: 209 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 268

Query: 66  YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125
             LD F+    +   +L LV  + +LLASK+EE     P++++   +   T      TK+
Sbjct: 269 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 321

Query: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYAD 185
            LL ME LLL+   ++L +PT   F+  YL               +C+    L     A 
Sbjct: 322 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR-----------QGVCVRTENL-----AK 365

Query: 186 YFLEVSLQDY-AFLNYAPSLVAAA--CVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCI 242
           Y  E+SL +   FL Y PSL+AAA  C+A+  +       WP  L   T YS   +V C+
Sbjct: 366 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCL 422

Query: 243 ERL 245
             L
Sbjct: 423 SEL 425


>gi|4502611 cyclin A1 isoform a [Homo sapiens]
          Length = 465

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 72/243 (29%), Positives = 111/243 (45%), Gaps = 34/243 (13%)

Query: 11  QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65
           + A +I+Q LR  E++      Y  + P ++  +R    D +  V   + L     +LAV
Sbjct: 210 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 269

Query: 66  YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125
             LD F+    +   +L LV  + +LLASK+EE     P++++   +   T      TK+
Sbjct: 270 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 322

Query: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYAD 185
            LL ME LLL+   ++L +PT   F+  YL               +C+    L     A 
Sbjct: 323 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR-----------QGVCVRTENL-----AK 366

Query: 186 YFLEVSLQDY-AFLNYAPSLVAAA--CVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCI 242
           Y  E+SL +   FL Y PSL+AAA  C+A+  +       WP  L   T YS   +V C+
Sbjct: 367 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCL 423

Query: 243 ERL 245
             L
Sbjct: 424 SEL 426


>gi|4502613 cyclin A [Homo sapiens]
          Length = 432

 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 74/264 (28%), Positives = 113/264 (42%), Gaps = 41/264 (15%)

Query: 15  DIHQALRYKELKLP---SYKGQSPQL--SLRRYFADLIAIVSNRFTLCPSARHLAVYLLD 69
           DIH  LR  E+K      Y  + P +  S+R    D +  V   + L     HLAV  +D
Sbjct: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240

Query: 70  LFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLH 129
            F+    +   +L LV  + +LLASKFEE     P++ +   +   T      TK+ +L 
Sbjct: 241 RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYP--PEVAEFVYITDDT-----YTKKQVLR 293

Query: 130 MELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLE 189
           ME L+L+   ++L  PT   F+  Y         LH       +E   +++        E
Sbjct: 294 MEHLVLKVLTFDLAAPTVNQFLTQYF--------LHQQPANCKVESLAMFLG-------E 338

Query: 190 VSLQDY-AFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIA 248
           +SL D   +L Y PS++A A    + +      +WP  L R T Y+ + L  C   L+  
Sbjct: 339 LSLIDADPYLKYLPSVIAGAAFHLA-LYTVTGQSWPESLIRKTGYTLESLKPC---LMDL 394

Query: 249 HDNDVKEANKQRGQAGPQSAQLSV 272
           H   +K          PQ AQ S+
Sbjct: 395 HQTYLK---------APQHAQQSI 409


>gi|4757930 cyclin B2 [Homo sapiens]
          Length = 398

 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 61/247 (24%), Positives = 108/247 (43%), Gaps = 32/247 (12%)

Query: 7   WWRGQLAAD----IHQALRYKELKL---PSY-KGQSPQLSLRRYFADLIAIVSNRFTLCP 58
           W   QL +D    I+Q LR  E+     P +  G+     +R    D +  V ++F L  
Sbjct: 125 WENPQLCSDYVKDIYQYLRQLEVLQSINPHFLDGRDINGRMRAILVDWLVQVHSKFRLLQ 184

Query: 59  SARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNM 118
              ++ V ++D F+    +S ++L LV ++ LLLASK+EE     P +E    +      
Sbjct: 185 ETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFS--PNIEDFVYI-----T 237

Query: 119 NLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKL 178
           +   T   +  ME L+L+  ++ L  P   HF+         + + H             
Sbjct: 238 DNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQH------------- 284

Query: 179 YMAKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFL 238
                A Y +E++L DY  ++Y PS VAAA    S+ +L     W  +    T Y+ + +
Sbjct: 285 ---TLAKYLMELTLIDYDMVHYHPSKVAAAASCLSQKVLG-QGKWNLKQQYYTGYTENEV 340

Query: 239 VQCIERL 245
           ++ ++ +
Sbjct: 341 LEVMQHM 347


>gi|16950655 cyclin D1 [Homo sapiens]
          Length = 295

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 59/205 (28%), Positives = 100/205 (48%), Gaps = 29/205 (14%)

Query: 63  LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVP-KLEQLNSLGCMTNMNLV 121
           LA+  LD F+    +   +L L+  +C+ +ASK +E   ++P   E+L    C+   N +
Sbjct: 80  LAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKE---TIPLTAEKL----CIYTDNSI 132

Query: 122 LTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMA 181
             ++ LL MELLL+   +WNL   T   FIE++LS+            M   E+ K  + 
Sbjct: 133 RPEE-LLQMELLLVNKLKWNLAAMTPHDFIEHFLSK------------MPEAEENKQIIR 179

Query: 182 KYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRL-SPTWPTRLHRLTAY------- 233
           K+A  F+ +   D  F++  PS+VAA  V ++   L L SP      +RLT +       
Sbjct: 180 KHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKC 239

Query: 234 SWDFLVQCIERLLIAHDNDVKEANK 258
             D L  C E++    ++ +++A +
Sbjct: 240 DPDCLRACQEQIEALLESSLRQAQQ 264


>gi|153791755 cyclin domain containing [Homo sapiens]
          Length = 350

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 50/178 (28%), Positives = 83/178 (46%), Gaps = 15/178 (8%)

Query: 50  VSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQL 109
           V  +F L   +  L V  LD F+    ++     L+ ++ LL+A K  + E   P+++QL
Sbjct: 143 VHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACK--QVEVHPPRVKQL 200

Query: 110 NSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWP 169
            +L C        ++Q L ++E ++L    + L  PT + F+E++    V          
Sbjct: 201 LALCCGA-----FSRQQLCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAE---- 251

Query: 170 MICLEKTKLYMAKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRL 227
                   L     A    E+SL DYAF +Y+PSL+A  C+A +  +LR+S     RL
Sbjct: 252 ----ASEALEAQALARGVAELSLADYAFTSYSPSLLAICCLALADRMLRVSRPVDLRL 305


>gi|14327896 cyclin B1 [Homo sapiens]
          Length = 433

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 55/235 (23%), Positives = 100/235 (42%), Gaps = 28/235 (11%)

Query: 15  DIHQALRYKELKL---PSYK-GQSPQLSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDL 70
           DI+  LR  E +    P Y  G+    ++R    D +  V  +F L     ++ V ++D 
Sbjct: 173 DIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDR 232

Query: 71  FMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHM 130
           FM    +  + L LV ++ + +ASK+EE         ++     +T+     TK  +  M
Sbjct: 233 FMQNNCVPKKMLQLVGVTAMFIASKYEEMYP-----PEIGDFAFVTDN--TYTKHQIRQM 285

Query: 131 ELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEV 190
           E+ +L    + L  P   HF+    +  + E D+                   A Y +E+
Sbjct: 286 EMKILRALNFGLGRPLPLHFLR--RASKIGEVDVE--------------QHTLAKYLMEL 329

Query: 191 SLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERL 245
           ++ DY  +++ PS +AA     +  IL      PT  H L +Y+ + L+  ++ L
Sbjct: 330 TMLDYDMVHFPPSQIAAGAFCLALKILDNGEWTPTLQHYL-SYTEESLLPVMQHL 383


>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
          Length = 292

 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 58/224 (25%), Positives = 94/224 (41%), Gaps = 23/224 (10%)

Query: 63  LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVL 122
           LA+  LD ++        QL L+   C+LLASK   +E +   +E+L    C+   + V 
Sbjct: 80  LAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKL--RETTPLTIEKL----CIYTDHAVS 133

Query: 123 TKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAK 182
            +Q L   E+L+L   +W+L    A  F+ + L       D             +  + K
Sbjct: 134 PRQ-LRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRD------------RQALVKK 180

Query: 183 YADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRL----TAYSWDFL 238
           +A  FL +   DY F  Y PS++A   + ++   L         L  L    T    D L
Sbjct: 181 HAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCL 240

Query: 239 VQCIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRP 282
             C E++  A    ++EA++      P++ + S  Q  SQ S P
Sbjct: 241 RACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTP 284


>gi|5802992 cyclin I [Homo sapiens]
          Length = 377

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 54/204 (26%), Positives = 89/204 (43%), Gaps = 24/204 (11%)

Query: 26  KLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLV 85
           K+PS +  SP  S R      +A +  +F L P    LA  LLD F+       + L  +
Sbjct: 33  KMPSNQNVSP--SQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCI 90

Query: 86  ALSCLLLASKFEEKEDSVPKLEQL---NSLGCMTNMNLVLTKQNLLHMELLLLETFQWNL 142
           A+SC  LA+K  E+++ +P L+ L   +  GC        +   +L ME ++L+   W+L
Sbjct: 91  AISCFFLAAKTVEEDERIPVLKVLARDSFCGC--------SSSEILRMERIILDKLNWDL 142

Query: 143 CLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEVSLQDYA---FLN 199
              T   F+  + + AV         P +     KL  +++     +  L   A    L 
Sbjct: 143 HTATPLDFLHIFHAIAVSTR------PQLLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQ 196

Query: 200 YAPSLVAAACVASSRIILRLSPTW 223
           +  S++A A V  S  + +L P W
Sbjct: 197 FRGSMLALAMV--SLEMEKLIPDW 218


>gi|4502617 cyclin D2 [Homo sapiens]
          Length = 289

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 46/151 (30%), Positives = 68/151 (45%), Gaps = 19/151 (12%)

Query: 63  LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVL 122
           LA+  LD F+         L L+   C+ LASK   KE S    E+L    C+   N + 
Sbjct: 79  LAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKL--KETSPLTAEKL----CIYTDNSI- 131

Query: 123 TKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAK 182
             Q LL  EL++L   +WNL   T   FIE+ L +   +            EK  L + K
Sbjct: 132 KPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQR-----------EKLSL-IRK 179

Query: 183 YADYFLEVSLQDYAFLNYAPSLVAAACVASS 213
           +A  F+ +   D+ F  Y PS++A   V ++
Sbjct: 180 HAQTFIALCATDFKFAMYPPSMIATGSVGAA 210


>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
          Length = 1395

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 50/227 (22%), Positives = 100/227 (44%), Gaps = 26/227 (11%)

Query: 21   RYKELKLPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDIS 78
            R ++  L  Y  +  +++  +R    D +  V   F +     +LAV L+DL++ +    
Sbjct: 1140 REEQFILTDYMNRQIEITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVDLYLMKAVCK 1199

Query: 79   IQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETF 138
              +L L+  +  ++A+KFEE     P+++    + C  N      +  +L ME+ +L   
Sbjct: 1200 KDKLQLLGATAFMIAAKFEEHNS--PRVDDFVYI-CDDNYQ----RSEVLSMEINILNVL 1252

Query: 139  QWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEVSLQDYAFL 198
            + ++ +P A HF+  Y +  +H               T +     + Y  E++LQ+Y ++
Sbjct: 1253 KCDINIPIAYHFLRRY-ARCIH---------------TNMKTLTLSRYICEMTLQEYHYV 1296

Query: 199  NYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERL 245
                S +AAA +  +  + +L   W   L   + YS   L   + +L
Sbjct: 1297 QEKASKLAAASLLLALYMKKLG-YWVPFLEHYSGYSISELHPLVRQL 1342


>gi|209862835 cyclin D3 isoform 1 [Homo sapiens]
          Length = 211

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 58/220 (26%), Positives = 94/220 (42%), Gaps = 27/220 (12%)

Query: 71  FMDRYDISIQ----QLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQN 126
           ++DRY   +     QL L+   C+LLASK   +E +   +E+L    C+   + V  +Q 
Sbjct: 3   YLDRYLSCVPTRKAQLQLLGAVCMLLASKL--RETTPLTIEKL----CIYTDHAVSPRQ- 55

Query: 127 LLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADY 186
           L   E+L+L   +W+L    A  F+ + L    H   L            +  + K+A  
Sbjct: 56  LRDWEVLVLGKLKWDLAAVIAHDFLAFIL----HRLSLP--------RDRQALVKKHAQT 103

Query: 187 FLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRL----TAYSWDFLVQCI 242
           FL +   DY F  Y PS++A   + ++   L         L  L    T    D L  C 
Sbjct: 104 FLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQ 163

Query: 243 ERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRP 282
           E++  A    ++EA++      P++ + S  Q  SQ S P
Sbjct: 164 EQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTP 203


>gi|16306525 cyclin B3 isoform 1 [Homo sapiens]
          Length = 291

 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 53/223 (23%), Positives = 97/223 (43%), Gaps = 32/223 (14%)

Query: 28  PSYKGQSPQ-----LSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQL 82
           PS   +SP      L  R  F DL  +    F +     +LAV L+DL++ +      +L
Sbjct: 43  PSSLQESPSSLQGALKKRSAFEDLTNV---SFEMTHETLYLAVKLVDLYLMKAVCKKDKL 99

Query: 83  HLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNL 142
            L+  +  ++A+KFEE     P+++    + C  N      +  +L ME+ +L   + ++
Sbjct: 100 QLLGATAFMIAAKFEEHNS--PRVDDFVYI-CDDNYQ----RSEVLSMEINILNVLKCDI 152

Query: 143 CLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEVSLQDYAFLNYAP 202
            +P A HF+  Y +  +H               T +     + Y  E++LQ+Y ++    
Sbjct: 153 NIPIAYHFLRRY-ARCIH---------------TNMKTLTLSRYICEMTLQEYHYVQEKA 196

Query: 203 SLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERL 245
           S +AAA +  +  + +L   W   L   + YS   L   + +L
Sbjct: 197 SKLAAASLLLALYMKKLG-YWVPFLEHYSGYSISELHPLVRQL 238


>gi|17318565 cyclin E2 [Homo sapiens]
          Length = 404

 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 49/210 (23%), Positives = 93/210 (44%), Gaps = 29/210 (13%)

Query: 39  LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFM-DRYDISIQQLHLVALSCLLLASKFE 97
           +R    D +  V   +TL     +LA    D FM  + DI+   L L+ ++ L +ASK E
Sbjct: 141 MRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLE 200

Query: 98  EKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSE 157
           E     PKL++   +      +   +++++L MEL++L+  +W LC  T   ++  +L  
Sbjct: 201 EIY--APKLQEFAYV-----TDGACSEEDILRMELIILKALKWELCPVTIISWLNLFL-- 251

Query: 158 AVHETDLHDGWPMICL----EKTKLYMAKYADYFLEVSLQDYAFLNYAPSLVAAACVASS 213
              + D     P + L    ++T + +A+  D  L +   D     Y     AA C  +S
Sbjct: 252 ---QVDALKDAPKVLLPQYSQETFIQIAQLLD--LCILAIDSLEFQYRILTAAALCHFTS 306

Query: 214 RIILRLSPTWPTRLHRLTAYSWDFLVQCIE 243
             +++          + +   WD + +C++
Sbjct: 307 IEVVK----------KASGLEWDSISECVD 326


>gi|40805832 cyclin G1 [Homo sapiens]
          Length = 295

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 5/94 (5%)

Query: 63  LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVL 122
           LAV LLD F+ +  +  + L  V LSC  LA K  E+E +VP    L  +          
Sbjct: 75  LAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRIS-----QYRF 129

Query: 123 TKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLS 156
           T  +L+ ME ++LE   W +   TA  F++ Y S
Sbjct: 130 TVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYS 163


>gi|4757934 cyclin G1 [Homo sapiens]
          Length = 295

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 5/94 (5%)

Query: 63  LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVL 122
           LAV LLD F+ +  +  + L  V LSC  LA K  E+E +VP    L  +          
Sbjct: 75  LAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRIS-----QYRF 129

Query: 123 TKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLS 156
           T  +L+ ME ++LE   W +   TA  F++ Y S
Sbjct: 130 TVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYS 163


>gi|118572588 cyclin F [Homo sapiens]
          Length = 786

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 41/196 (20%), Positives = 88/196 (44%), Gaps = 26/196 (13%)

Query: 47  IAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKL 106
           +A + +  +LC    HL V  +D ++ R  +   +L L+ ++C+++ ++F  KE     +
Sbjct: 320 VATMKDFTSLC---LHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKE-----I 371

Query: 107 EQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHD 166
             +     +T+       ++L+ M   ++   +  + +PT   + E  L+          
Sbjct: 372 LTIREAVWLTDNTYKY--EDLVRMMGEIVSALEGKIRVPTVVDYKEVLLT---------- 419

Query: 167 GWPMICLEKTKLYMAKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTR 226
                 L   +L       +  E+SL   +   YAP+ +AAA +  +R+    +  W T+
Sbjct: 420 ------LVPVELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQ 473

Query: 227 LHRLTAYSWDFLVQCI 242
           L  LT +S++ L+ C+
Sbjct: 474 LWDLTGFSYEDLIPCV 489


>gi|89886237 cyclin I family, member 2 [Homo sapiens]
          Length = 369

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 28/128 (21%), Positives = 58/128 (45%), Gaps = 8/128 (6%)

Query: 30  YKGQSPQLSLRRYFADLIAIV---SNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVA 86
           ++G  PQ  +   F +++  +    N F    S  +LA+ +    +    +  + LH   
Sbjct: 137 WRGGKPQDEICDAFEEVVLWLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCAT 196

Query: 87  LSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPT 146
           ++ L LA+K  E+E+ +P+++         +     +   LL MEL +L+   W+L + T
Sbjct: 197 ITSLRLAAKVNEEEEFIPQVKDFTK-----HYGSDYSPNELLRMELAILDRLHWDLYIGT 251

Query: 147 AAHFIEYY 154
              F+  +
Sbjct: 252 PLDFLTIF 259


>gi|209915553 cyclin D3 isoform 3 [Homo sapiens]
          Length = 220

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 41/170 (24%), Positives = 67/170 (39%), Gaps = 16/170 (9%)

Query: 117 NMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKT 176
           +M  +L    L   E+L+L   +W+L    A  F+ + L       D             
Sbjct: 55  HMRKMLAYWMLEDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRD------------R 102

Query: 177 KLYMAKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRL----TA 232
           +  + K+A  FL +   DY F  Y PS++A   + ++   L         L  L    T 
Sbjct: 103 QALVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITG 162

Query: 233 YSWDFLVQCIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRP 282
              D L  C E++  A    ++EA++      P++ + S  Q  SQ S P
Sbjct: 163 TEVDCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTP 212


>gi|17318559 cyclin E1 isoform 1 [Homo sapiens]
          Length = 410

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 40/186 (21%), Positives = 81/186 (43%), Gaps = 31/186 (16%)

Query: 66  YLLDLFMDRYDISIQQ-----LHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
           YL   F DRY  + +      L L+ +S L +A+K EE     PKL Q   +      + 
Sbjct: 167 YLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYP--PKLHQFAYV-----TDG 219

Query: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180
             +   +L MEL++++  +W L   T   ++  Y+ +  +  DLH+    + L +    +
Sbjct: 220 ACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYM-QVAYLNDLHE----VLLPQYPQQI 274

Query: 181 AKYADYFLEVSLQDYAFLNYAPSLVAAACV---ASSRIILRLSPTWPTRLHRLTAYSWDF 237
                  L++ + D   L +   ++AA+ +   +SS +           + +++ Y W  
Sbjct: 275 FIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSEL-----------MQKVSGYQWCD 323

Query: 238 LVQCIE 243
           +  C++
Sbjct: 324 IENCVK 329


>gi|17318561 cyclin E1 isoform 2 [Homo sapiens]
          Length = 395

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 40/186 (21%), Positives = 81/186 (43%), Gaps = 31/186 (16%)

Query: 66  YLLDLFMDRYDISIQQ-----LHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNL 120
           YL   F DRY  + +      L L+ +S L +A+K EE     PKL Q   +      + 
Sbjct: 152 YLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYP--PKLHQFAYV-----TDG 204

Query: 121 VLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYM 180
             +   +L MEL++++  +W L   T   ++  Y+ +  +  DLH+    + L +    +
Sbjct: 205 ACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYM-QVAYLNDLHE----VLLPQYPQQI 259

Query: 181 AKYADYFLEVSLQDYAFLNYAPSLVAAACV---ASSRIILRLSPTWPTRLHRLTAYSWDF 237
                  L++ + D   L +   ++AA+ +   +SS +           + +++ Y W  
Sbjct: 260 FIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSEL-----------MQKVSGYQWCD 308

Query: 238 LVQCIE 243
           +  C++
Sbjct: 309 IENCVK 314


>gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 307

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 41/185 (22%), Positives = 73/185 (39%), Gaps = 35/185 (18%)

Query: 39  LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEE 98
           +R    D +  V     L     +LAV+LLD ++    + + +L L+ ++CL +A K EE
Sbjct: 107 MRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEE 166

Query: 99  KEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEA 158
                P      +  C+ + +   ++  LL  E  +L    +                  
Sbjct: 167 CVLPEP------AFLCLLSAD-SFSRAELLRAERRILSRLDFR----------------- 202

Query: 159 VHETDLHDGWPMIC------LEKTKLYMAKYADYFLEVSLQDYAFLNYAPSLVAAACVAS 212
                LH   P++C      L  +   +   A YFLE+SL +     + P   AAA ++ 
Sbjct: 203 -----LHHPGPLLCLGLLAALAGSSPQVMLLATYFLELSLLEAEAAGWEPGRRAAAALSL 257

Query: 213 SRIIL 217
           +  +L
Sbjct: 258 AHRLL 262


>gi|4757936 cyclin G2 [Homo sapiens]
          Length = 344

 Score = 37.7 bits (86), Expect = 0.017
 Identities = 26/116 (22%), Positives = 51/116 (43%), Gaps = 5/116 (4%)

Query: 39  LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEE 98
           LR    + +  ++N F  C     LAV +LD F+    +  + L  + +   LLA++  E
Sbjct: 55  LRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVE 114

Query: 99  KEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYY 154
           ++ ++P    +  +          T  ++  ME ++ E   + L   TA +F+  Y
Sbjct: 115 EDCNIPSTHDVIRIS-----QCKCTASDIKRMEKIISEKLHYELEATTALNFLHLY 165


>gi|4502623 cyclin H [Homo sapiens]
          Length = 323

 Score = 37.7 bits (86), Expect = 0.017
 Identities = 37/140 (26%), Positives = 64/140 (45%), Gaps = 18/140 (12%)

Query: 78  SIQQLH--LVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTK--QNLLHMELL 133
           S+ + H  ++ L+C  LA K +E   S P+      +G +    L   K  + +L  ELL
Sbjct: 95  SVMEYHPRIIMLTCAFLACKVDEFNVSSPQF-----VGNLRESPLGQEKALEQILEYELL 149

Query: 134 LLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEVSLQ 193
           L++   ++L +       E +L       DL   +P+  LE  ++      D+   ++L 
Sbjct: 150 LIQQLNFHLIVHNPYRPFEGFL------IDLKTRYPI--LENPEILRKTADDFLNRIALT 201

Query: 194 DYAFLNYAPSLVAAACVASS 213
           D A+L Y PS +A   + SS
Sbjct: 202 D-AYLLYTPSQIALTAILSS 220


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.133    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,225,123
Number of Sequences: 37866
Number of extensions: 596800
Number of successful extensions: 1621
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 1548
Number of HSP's gapped (non-prelim): 53
length of query: 383
length of database: 18,247,518
effective HSP length: 104
effective length of query: 279
effective length of database: 14,309,454
effective search space: 3992337666
effective search space used: 3992337666
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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