Guide to the Human Genome
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Search of human proteins with 197276602

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|197276602 microtubule-associated protein 4 isoform 5 [Homo
sapiens]
         (817 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sa...  1607   0.0  
gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sap...  1557   0.0  
gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sap...   771   0.0  
gi|197276600 microtubule-associated protein 4 isoform 4 [Homo sa...   644   0.0  
gi|178557734 microtubule-associated protein tau isoform 6 [Homo ...   169   1e-41
gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sap...   169   1e-41
gi|87578392 microtubule-associated protein 2 isoform 2 [Homo sap...   167   5e-41
gi|82534351 microtubule-associated protein tau isoform 1 [Homo s...   162   9e-40
gi|87578255 microtubule-associated protein 2 isoform 4 [Homo sap...   156   8e-38
gi|87578394 microtubule-associated protein 2 isoform 5 [Homo sap...   154   2e-37
gi|8400715 microtubule-associated protein tau isoform 4 [Homo sa...   151   2e-36
gi|6754638 microtubule-associated protein tau isoform 2 [Homo sa...   145   1e-34
gi|178557736 microtubule-associated protein tau isoform 5 [Homo ...   142   2e-33
gi|8400711 microtubule-associated protein tau isoform 3 [Homo sa...   141   3e-33
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   96   2e-19
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    96   2e-19
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   92   3e-18
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   92   3e-18
gi|110349719 titin isoform N2-A [Homo sapiens]                         80   1e-14
gi|116284392 mucin 2 precursor [Homo sapiens]                          80   1e-14
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]           77   6e-14
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]    73   1e-12
gi|163965366 nascent polypeptide-associated complex alpha subuni...    72   2e-12
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    72   2e-12
gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ...    72   3e-12
gi|150170670 piccolo isoform 2 [Homo sapiens]                          69   1e-11
gi|150378539 piccolo isoform 1 [Homo sapiens]                          69   1e-11
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     68   4e-11
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             67   7e-11
gi|91982772 mucin 17 [Homo sapiens]                                    66   1e-10

>gi|197276602 microtubule-associated protein 4 isoform 5 [Homo
           sapiens]
          Length = 817

 Score = 1607 bits (4162), Expect = 0.0
 Identities = 817/817 (100%), Positives = 817/817 (100%)

Query: 1   METTGDQGIEGMAYMDENRNITFTCPRTPSELINKSSPLEVLESAACEKLPTPTPQVVKE 60
           METTGDQGIEGMAYMDENRNITFTCPRTPSELINKSSPLEVLESAACEKLPTPTPQVVKE
Sbjct: 1   METTGDQGIEGMAYMDENRNITFTCPRTPSELINKSSPLEVLESAACEKLPTPTPQVVKE 60

Query: 61  GDSFPDTLAKNGQEIAPAQISKSLMVDNYTKDGVPGQERPKGPSAVVPSTSTGGVALPIT 120
           GDSFPDTLAKNGQEIAPAQISKSLMVDNYTKDGVPGQERPKGPSAVVPSTSTGGVALPIT
Sbjct: 61  GDSFPDTLAKNGQEIAPAQISKSLMVDNYTKDGVPGQERPKGPSAVVPSTSTGGVALPIT 120

Query: 121 TAIETVNIHGDHSLKNKAELADSMKNEAGIDEGHVIGESESVHSGASKHSVEKVTELAKG 180
           TAIETVNIHGDHSLKNKAELADSMKNEAGIDEGHVIGESESVHSGASKHSVEKVTELAKG
Sbjct: 121 TAIETVNIHGDHSLKNKAELADSMKNEAGIDEGHVIGESESVHSGASKHSVEKVTELAKG 180

Query: 181 HLLPGVPVEDQSLPGEARALEGYADRGNFPAHPVNEEKETKEGSVAVQIPDLLEDKAQKL 240
           HLLPGVPVEDQSLPGEARALEGYADRGNFPAHPVNEEKETKEGSVAVQIPDLLEDKAQKL
Sbjct: 181 HLLPGVPVEDQSLPGEARALEGYADRGNFPAHPVNEEKETKEGSVAVQIPDLLEDKAQKL 240

Query: 241 SFCEDQNAQDRNSKGSDSLNKKVDLTLLSPKSENDKLKEISLACKITELESVSLPTPEIQ 300
           SFCEDQNAQDRNSKGSDSLNKKVDLTLLSPKSENDKLKEISLACKITELESVSLPTPEIQ
Sbjct: 241 SFCEDQNAQDRNSKGSDSLNKKVDLTLLSPKSENDKLKEISLACKITELESVSLPTPEIQ 300

Query: 301 SDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEKSESKTPGEGKKED 360
           SDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEKSESKTPGEGKKED
Sbjct: 301 SDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEKSESKTPGEGKKED 360

Query: 361 KSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDI 420
           KSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDI
Sbjct: 361 KSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDI 420

Query: 421 TTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLAS 480
           TTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLAS
Sbjct: 421 TTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLAS 480

Query: 481 GLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQ 540
           GLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQ
Sbjct: 481 GLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQ 540

Query: 541 TVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTS 600
           TVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTS
Sbjct: 541 TVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTS 600

Query: 601 TSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLAT 660
           TSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLAT
Sbjct: 601 TSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLAT 660

Query: 661 NTSAPDLKNVRSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSKANIKHKPGGGDV 720
           NTSAPDLKNVRSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSKANIKHKPGGGDV
Sbjct: 661 NTSAPDLKNVRSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSKANIKHKPGGGDV 720

Query: 721 KIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAP 780
           KIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAP
Sbjct: 721 KIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAP 780

Query: 781 EAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETN 817
           EAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETN
Sbjct: 781 EAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETN 817


>gi|47519675 microtubule-associated protein 4 isoform 2 [Homo
           sapiens]
          Length = 887

 Score = 1557 bits (4032), Expect = 0.0
 Identities = 809/886 (91%), Positives = 812/886 (91%), Gaps = 69/886 (7%)

Query: 1   METTGDQGIEGMAYMDENRNITFTCPRTPSELINKSSPLEVLESAACEKLPTPTPQVVKE 60
           METTGDQGIEGMAYMDENRNITFTCPRTPSELINKSSPLEVLESAACEKLPTPTPQVVKE
Sbjct: 1   METTGDQGIEGMAYMDENRNITFTCPRTPSELINKSSPLEVLESAACEKLPTPTPQVVKE 60

Query: 61  GDSFPDTLAKNGQEIAPAQISKSLMVDNYTKDGVPGQERPKGPSAVVPSTSTGGVALPIT 120
           GDSFPDTLAKNGQEIAPAQISKSLMVDNYTKDGVPGQERPKGPSAVVPSTSTGGVALPIT
Sbjct: 61  GDSFPDTLAKNGQEIAPAQISKSLMVDNYTKDGVPGQERPKGPSAVVPSTSTGGVALPIT 120

Query: 121 TAIETVNIHGDHSLKNKAELADSMKNEAGIDEGHVIGESESVHSGASKHSVEKVTELAKG 180
           TAIETVNIHGDHSLKNKAELADSMKNEAGIDEGHVIGESESVHSGASKHSVEKVTELAKG
Sbjct: 121 TAIETVNIHGDHSLKNKAELADSMKNEAGIDEGHVIGESESVHSGASKHSVEKVTELAKG 180

Query: 181 HLLPGVPVEDQSLPGEARALEGYADRGNFPAHPVNEEKETKEGSVAVQIPDLLEDKAQKL 240
           HLLPGVPVEDQSLPGEARALEGYADRGNFPAHPVNEEKETKEGSVAVQIPDLLEDKAQKL
Sbjct: 181 HLLPGVPVEDQSLPGEARALEGYADRGNFPAHPVNEEKETKEGSVAVQIPDLLEDKAQKL 240

Query: 241 SFCEDQNAQDRNSKGSDSLNKKVDLTLLSPKSENDKLKEISLACKITELESVSLPTPEIQ 300
           SFCEDQNAQDRNSKGSDSLNKKVDLTLLSPKSENDKLKEISLACKITELESVSLPTPEIQ
Sbjct: 241 SFCEDQNAQDRNSKGSDSLNKKVDLTLLSPKSENDKLKEISLACKITELESVSLPTPEIQ 300

Query: 301 SDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEKSESKTPGEGKKED 360
           SDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEKSESKTPGEGKKED
Sbjct: 301 SDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEKSESKTPGEGKKED 360

Query: 361 KSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDI 420
           KSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDI
Sbjct: 361 KSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDI 420

Query: 421 TTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLAS 480
           TTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLAS
Sbjct: 421 TTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLAS 480

Query: 481 GLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQ 540
           GLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQ
Sbjct: 481 GLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQ 540

Query: 541 TVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTS 600
           TVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTS
Sbjct: 541 TVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTS 600

Query: 601 TSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLAT 660
           TSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLAT
Sbjct: 601 TSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLAT 660

Query: 661 NTSAPDLKNVRSKVGSTENIKHQPGGGR-------------------------------- 688
           NTSAPDLKNVRSKVGSTENIKHQPGGGR                                
Sbjct: 661 NTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQ 720

Query: 689 ------VQIQNKKVDISKVSSK-------------------------------CGSKANI 711
                 VQI +KKV  S + SK                               CGSKANI
Sbjct: 721 KQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANI 780

Query: 712 KHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGE 771
           KHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGE
Sbjct: 781 KHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGE 840

Query: 772 EPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETN 817
           EPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQET+
Sbjct: 841 EPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETS 886


>gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sapiens]
          Length = 1152

 Score =  771 bits (1990), Expect = 0.0
 Identities = 431/588 (73%), Positives = 447/588 (76%), Gaps = 92/588 (15%)

Query: 306  SKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEK-------SESKTPGEGKK 358
            S+ EA P  + D  +  T  KG+     +D  LE+ Q + +        S     G GKK
Sbjct: 580  SETEATPVPIKDMEIAQT-QKGIS----EDSHLESLQDVGQSAAPTFMISPETVTGTGKK 634

Query: 359  EDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGN 418
               S  AE         +   L  L  +     Q      +++GIARPEEGRPVVSGTGN
Sbjct: 635  --CSLPAE---------EDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGN 683

Query: 419  DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSL 478
            DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSL
Sbjct: 684  DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSL 743

Query: 479  ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS 538
            ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS
Sbjct: 744  ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS 803

Query: 539  TQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS 598
            TQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS
Sbjct: 804  TQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS 863

Query: 599  TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 658
            TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL
Sbjct: 864  TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 923

Query: 659  ATNTSAPDLKNVRSKVGSTENIKHQPGGGR------------------------------ 688
            ATNTSAPDLKNVRSKVGSTENIKHQPGGGR                              
Sbjct: 924  ATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIAS 983

Query: 689  --------VQIQNKKVDISKVSSK-------------------------------CGSKA 709
                    VQI +KKV  S + SK                               CGSKA
Sbjct: 984  AQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKA 1043

Query: 710  NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPA 769
            NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPA
Sbjct: 1044 NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPA 1103

Query: 770  GEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETN 817
            GEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQET+
Sbjct: 1104 GEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETS 1151


>gi|197276600 microtubule-associated protein 4 isoform 4 [Homo
            sapiens]
          Length = 1135

 Score =  644 bits (1662), Expect = 0.0
 Identities = 369/526 (70%), Positives = 384/526 (73%), Gaps = 92/526 (17%)

Query: 306  SKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEK-------SESKTPGEGKK 358
            S+ EA P  + D  +  T  KG+     +D  LE+ Q + +        S     G GKK
Sbjct: 580  SETEATPVPIKDMEIAQT-QKGIS----EDSHLESLQDVGQSAAPTFMISPETVTGTGKK 634

Query: 359  EDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGN 418
               S  AE         +   L  L  +     Q      +++GIARPEEGRPVVSGTGN
Sbjct: 635  --CSLPAE---------EDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGN 683

Query: 419  DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSL 478
            DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSL
Sbjct: 684  DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSL 743

Query: 479  ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS 538
            ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS
Sbjct: 744  ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS 803

Query: 539  TQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS 598
            TQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS
Sbjct: 804  TQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS 863

Query: 599  TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 658
            TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL
Sbjct: 864  TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 923

Query: 659  ATNTSAPDLKNVRSKVGSTENIKHQPGGGR------------------------------ 688
            ATNTSAPDLKNVRSKVGSTENIKHQPGGGR                              
Sbjct: 924  ATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIAS 983

Query: 689  --------VQIQNKKVDISKVSSK-------------------------------CGSKA 709
                    VQI +KKV  S + SK                               CGSKA
Sbjct: 984  AQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKA 1043

Query: 710  NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 755
            NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVK E
Sbjct: 1044 NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKIE 1089


>gi|178557734 microtubule-associated protein tau isoform 6 [Homo
           sapiens]
          Length = 776

 Score =  169 bits (428), Expect = 1e-41
 Identities = 132/394 (33%), Positives = 183/394 (46%), Gaps = 70/394 (17%)

Query: 399 KSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTST-SKAKT--- 454
           K A +  P E +P  +  G  ++  P  +     + K    +  + AKTST S AKT   
Sbjct: 347 KEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKN 406

Query: 455 QPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADA 514
           +P   PK P P    G +   +  +S  V   PP  P   S+  S   S   K   +  A
Sbjct: 407 RPCLSPKHPTP----GSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGA 462

Query: 515 KAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKT 574
               K A+P + A+ P  +  + +T+  AKT  A     T PSS +        P   ++
Sbjct: 463 DGKTKIATP-RGAAPPGQKGQANATRIPAKTPPAP---KTPPSSATKQVQRRPPPAGPRS 518

Query: 575 E-GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRP 633
           E G+P +    +  S P     P S S +            P+    P+R      P + 
Sbjct: 519 ERGEPPKSGDRSGYSSPGSPGTPGSRSRT------------PSLPTPPTRE-----PKKV 561

Query: 634 STTPFIDKKPTSAKPSSTTPRLSRLATN-TSAPDLKNVRSKVGSTENIKHQPGGGRVQIQ 692
           +      K P+SAK        SRL T     PDLKNV+SK+GSTEN+KHQPGGG+VQI 
Sbjct: 562 AVVRTPPKSPSSAK--------SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQII 613

Query: 693 NKKVDISKVSSKCGSKANIKH-------------------------------KPGGGDVK 721
           NKK+D+S V SKCGSK NIKH                               KPGGG V+
Sbjct: 614 NKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVE 673

Query: 722 IESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 755
           ++S+KL+FK++ Q+K+GSLDN+ H+P GG  K E
Sbjct: 674 VKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 707



 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 86/400 (21%), Positives = 146/400 (36%), Gaps = 42/400 (10%)

Query: 400 SAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSL 459
           + G  RP     V      D ++P +     SP  K  P    +P +T+  +A    TS+
Sbjct: 206 AGGKERPGSKEEVDEDRDVDESSPQD-----SPPSKASPAQDGRPPQTAAREA----TSI 256

Query: 460 PKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSK-----DVKPKPIADA 514
           P  PA   I  L    +S  S  +PA+ P  P+V  A+    P +     ++ P    + 
Sbjct: 257 PGFPAEGAIP-LPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQ 315

Query: 515 KAPEKR----ASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPT 570
              E+     A P  P   P +R  S     + + T  A +    PS + P+     KP 
Sbjct: 316 AHSEEHLGRAAFPGAPGEGPEARGPS-----LGEDTKEADLPE--PSEKQPAAAPRGKPV 368

Query: 571 AIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPM- 629
           +   + K     +M +KS     S  K   TS+     TL      +   P+   + P+ 
Sbjct: 369 SRVPQLKA----RMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLI 424

Query: 630 -PSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGR 688
            PS P+  P         +P S+   +S + + T +   K ++ K    +     P G  
Sbjct: 425 QPSSPAVCP---------EPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAA 475

Query: 689 VQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPA 748
              Q  + + +++ +K               V+        + +      S D  G+  +
Sbjct: 476 PPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGY-SS 534

Query: 749 GGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSA 788
            G+  T G  S  P  P PP  E   ++       +P+SA
Sbjct: 535 PGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSA 574


>gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sapiens]
          Length = 1827

 Score =  169 bits (427), Expect = 1e-41
 Identities = 129/375 (34%), Positives = 187/375 (49%), Gaps = 34/375 (9%)

Query: 390  QEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTST 449
            +E++  K+ + + + +  + +P  +G G  I+TP  K     P       +T    +   
Sbjct: 1409 KEEKAEKEARRSSLEKHRKEKPFKTGRGR-ISTPERKVAKKEP-------STVSRDEVRR 1460

Query: 450  SKAKTQPTSLPKQPAPTTIGGLNK---KPMSLASGLVPAAPPKRPAVASARPSIL-PS-- 503
             KA  +   L K+          K   KP    +     +  KR   A+   S L PS  
Sbjct: 1461 KKAVYKKAELAKKTEVQAHSPSRKFILKPAIKYTRPTHLSCVKRKTTAAGGESALAPSVF 1520

Query: 504  KDVKPKPIADA--KAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSP 561
            K  K K ++D   K+PEKR+S  +P+S    R G    +     +  ++++S+   +   
Sbjct: 1521 KQAKDK-VSDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRS 1579

Query: 562  STLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSR-PKSTSTSSMKKTTTLSGTAPAAGVV 620
              +     +   T   P     +T  + P+  SR P +  T S  +T    GT  +A +V
Sbjct: 1580 EPIRRAGKSGTSTPTTPGSTA-ITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILV 1638

Query: 621  PSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENI 680
            PS  K   + + P               S  TP+  RL  N   PDLKNV+SK+GST+NI
Sbjct: 1639 PSEKKVAIIRTPPK--------------SPATPKQLRLI-NQPLPDLKNVKSKIGSTDNI 1683

Query: 681  KHQPGGGRVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSL 740
            K+QP GG+VQI  KK+D+S V+SKCGS  NI+H+PGGG VKIES KL+FKEKAQAKVGSL
Sbjct: 1684 KYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSL 1743

Query: 741  DNVGHLPAGGAVKTE 755
            DN  H+P GG VK +
Sbjct: 1744 DNAHHVPGGGNVKID 1758


>gi|87578392 microtubule-associated protein 2 isoform 2 [Homo
           sapiens]
          Length = 471

 Score =  167 bits (422), Expect = 5e-41
 Identities = 112/287 (39%), Positives = 155/287 (54%), Gaps = 31/287 (10%)

Query: 483 VPAAPPKRPA---------VASARPSILPS--KDVKPKPIADA--KAPEKRASPSKPASA 529
           +P +PP  PA          A    ++ PS  K  K K ++D   K+PEKR+S  +P+S 
Sbjct: 133 LPPSPPPSPASEQTVTVEEAAGGESALAPSVFKQAKDK-VSDGVTKSPEKRSSLPRPSSI 191

Query: 530 PASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSV 589
              R G    +     +  ++++S+   +     +     +   T   P     +T  + 
Sbjct: 192 LPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTA-ITPGTP 250

Query: 590 PADLSR-PKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKP 648
           P+  SR P +  T S  +T    GT  +A +VPS  K   + + P               
Sbjct: 251 PSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPK-------------- 296

Query: 649 SSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSK 708
           S  TP+  RL  N   PDLKNV+SK+GST+NIK+QP GG+VQI  KK+D+S V+SKCGS 
Sbjct: 297 SPATPKQLRLI-NQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSL 355

Query: 709 ANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 755
            NI+H+PGGG VKIES KL+FKEKAQAKVGSLDN  H+P GG VK +
Sbjct: 356 KNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKID 402


>gi|82534351 microtubule-associated protein tau isoform 1 [Homo
           sapiens]
          Length = 758

 Score =  162 bits (411), Expect = 9e-40
 Identities = 133/399 (33%), Positives = 173/399 (43%), Gaps = 98/399 (24%)

Query: 399 KSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTST-SKAKTQPT 457
           K A +  P E +P  +  G  ++  P  +     + K    +  + AKTST S AKT   
Sbjct: 347 KEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKN 406

Query: 458 SLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAP 517
                                     P   PK P   S+ P I PS        + A  P
Sbjct: 407 R-------------------------PCLSPKHPTPGSSDPLIQPS--------SPAVCP 433

Query: 518 EKRASPSKPASAPASRSGSKSTQTV--------AKTTTAAAVASTGPSSRSPSTLLPKK- 568
           E  +SP K  S+  SR+GS   + +         K  T    A  G   ++ +T +P K 
Sbjct: 434 EPPSSP-KHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKT 492

Query: 569 PTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATP 628
           P A KT     E  K   +S     S P S  T   +  T    T P        V  TP
Sbjct: 493 PPAPKTPPSSGEPPKSGDRS---GYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP 549

Query: 629 MPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATN-TSAPDLKNVRSKVGSTENIKHQPGGG 687
                       K P+SAK        SRL T     PDLKNV+SK+GSTEN+KHQPGGG
Sbjct: 550 -----------PKSPSSAK--------SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGG 590

Query: 688 RVQIQNKKVDISKVSSKCGSKANIKH-------------------------------KPG 716
           +VQI NKK+D+S V SKCGSK NIKH                               KPG
Sbjct: 591 KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPG 650

Query: 717 GGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 755
           GG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG  K E
Sbjct: 651 GGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 689



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 85/400 (21%), Positives = 143/400 (35%), Gaps = 60/400 (15%)

Query: 400 SAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSL 459
           + G  RP     V      D ++P +     SP  K  P    +P +T+  +A    TS+
Sbjct: 206 AGGKERPGSKEEVDEDRDVDESSPQD-----SPPSKASPAQDGRPPQTAAREA----TSI 256

Query: 460 PKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSK-----DVKPKPIADA 514
           P  PA   I  L    +S  S  +PA+ P  P+V  A+    P +     ++ P    + 
Sbjct: 257 PGFPAEGAIP-LPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQ 315

Query: 515 KAPEKR----ASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPT 570
              E+     A P  P   P +R  S     + + T  A +    PS + P+     KP 
Sbjct: 316 AHSEEHLGRAAFPGAPGEGPEARGPS-----LGEDTKEADLPE--PSEKQPAAAPRGKPV 368

Query: 571 AIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPM- 629
           +   + K     +M +KS     S  K   TS+     TL      +   P+   + P+ 
Sbjct: 369 SRVPQLKA----RMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLI 424

Query: 630 -PSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGR 688
            PS P+  P         +P S+   +S + + T +   K ++ K    +     P G  
Sbjct: 425 QPSSPAVCP---------EPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAA 475

Query: 689 VQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPA 748
              Q  + + +++ +K       K  P  G+      +  +                   
Sbjct: 476 PPGQKGQANATRIPAKTPPAP--KTPPSSGEPPKSGDRSGYSSP---------------- 517

Query: 749 GGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSA 788
            G+  T G  S  P  P PP  E   ++       +P+SA
Sbjct: 518 -GSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSA 556


>gi|87578255 microtubule-associated protein 2 isoform 4 [Homo
           sapiens]
          Length = 502

 Score =  156 bits (394), Expect = 8e-38
 Identities = 113/306 (36%), Positives = 150/306 (49%), Gaps = 38/306 (12%)

Query: 483 VPAAPPKRPA---------VASARPSILPS--KDVKPKPIADA--KAPEKRASPSKPASA 529
           +P +PP  PA          A    ++ PS  K  K K ++D   K+PEKR+S  +P+S 
Sbjct: 133 LPPSPPPSPASEQTVTVEEAAGGESALAPSVFKQAKDK-VSDGVTKSPEKRSSLPRPSSI 191

Query: 530 PASRSG-------------SKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEG 576
              R G             S  + +  +TT +  +   G S  S  T      TAI T G
Sbjct: 192 LPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTT--PGSTAI-TPG 248

Query: 577 KPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVV--PSRVKATPMPSRPS 634
            P      T    P   S P++  T    K+  L  +     ++  P +  ATP   R  
Sbjct: 249 TPPSYSSRTP-GTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLI 307

Query: 635 TTPFIDKKPTSAKPSSTT-----PRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRV 689
             P  D K   +K  ST      P+  ++       D   V+S+ GS +NIKH  GGG V
Sbjct: 308 NQPLPDLKNVKSKIGSTDNIKYQPKGGQVRILNKKIDFSKVQSRCGSKDNIKHSAGGGNV 367

Query: 690 QIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAG 749
           QI  KK+D+S V+SKCGS  NI+H+PGGG VKIES KL+FKEKAQAKVGSLDN  H+P G
Sbjct: 368 QIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGG 427

Query: 750 GAVKTE 755
           G VK +
Sbjct: 428 GNVKID 433


>gi|87578394 microtubule-associated protein 2 isoform 5 [Homo
           sapiens]
          Length = 559

 Score =  154 bits (390), Expect = 2e-37
 Identities = 131/402 (32%), Positives = 178/402 (44%), Gaps = 57/402 (14%)

Query: 391 EQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSP--------EKKTKPLATT 442
           EQE+  Q K    A P       +        PP+   PPSP        E+     +  
Sbjct: 109 EQEKEAQHKDQTAALPLAAEETAN-------LPPSP--PPSPASEQTVTVEEAAGGESAL 159

Query: 443 QPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPK---------RPAV 493
            P+    +K K   ++L K PA   + G  K P    S   P+   +         +P  
Sbjct: 160 APSVFKQAKDKVSNSTLSKIPA---LQGSTKSPRY--SSACPSTTKRATFSDSLLIQPTS 214

Query: 494 ASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSG-------------SKSTQ 540
           A +   +  SK      +   K+PEKR+S  +P+S    R G             S  + 
Sbjct: 215 AGSTDRLPYSKSGNKDGVT--KSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISS 272

Query: 541 TVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTS 600
           +  +TT +  +   G S  S  T      TAI T G P      T    P   S P++  
Sbjct: 273 SARRTTRSEPIRRAGKSGTSTPTT--PGSTAI-TPGTPPSYSSRTP-GTPGTPSYPRTPH 328

Query: 601 TSSMKKTTTLSGTAPAAGVV--PSRVKATPMPSRPSTTPFIDKKPTSAKPSSTT-----P 653
           T    K+  L  +     ++  P +  ATP   R    P  D K   +K  ST      P
Sbjct: 329 TPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSKIGSTDNIKYQP 388

Query: 654 RLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSKANIKH 713
           +  ++       D   V+S+ GS +NIKH  GGG VQI  KK+D+S V+SKCGS  NI+H
Sbjct: 389 KGGQVRILNKKIDFSKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRH 448

Query: 714 KPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 755
           +PGGG VKIES KL+FKEKAQAKVGSLDN  H+P GG VK +
Sbjct: 449 RPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKID 490


>gi|8400715 microtubule-associated protein tau isoform 4 [Homo
           sapiens]
          Length = 352

 Score =  151 bits (382), Expect = 2e-36
 Identities = 95/222 (42%), Positives = 120/222 (54%), Gaps = 24/222 (10%)

Query: 536 SKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKK-PTAIKTEGKPAEVKKMTAKSVPADLS 594
           +K      K  T    A  G   ++ +T +P K P A KT     E  K   +S     S
Sbjct: 84  AKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRS---GYS 140

Query: 595 RPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPR 654
            P S  T   +  T    T P        V  TP            K P+SAK       
Sbjct: 141 SPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP-----------PKSPSSAK------- 182

Query: 655 LSRLATN-TSAPDLKNVRSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSKANIKH 713
            SRL T     PDLKNV+SK+GSTEN+KHQPGGG+VQI  K VD+SKV+SKCGS  NI H
Sbjct: 183 -SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHH 241

Query: 714 KPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 755
           KPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG  K E
Sbjct: 242 KPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 283



 Score = 87.4 bits (215), Expect = 5e-17
 Identities = 70/224 (31%), Positives = 100/224 (44%), Gaps = 43/224 (19%)

Query: 514 AKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIK 573
           AK P    +P  P+S    +SG +S  +   +       S  PS  +P T  PKK   ++
Sbjct: 115 AKTPPAPKTP--PSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 172

Query: 574 TEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRP 633
           T                     PKS S++  +       TAP            PMP   
Sbjct: 173 TP--------------------PKSPSSAKSRLQ-----TAP-----------VPMPDLK 196

Query: 634 STTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRVQIQN 693
           +    +  K  S +     P   ++       DL  V SK GS  NI H+PGGG+V++++
Sbjct: 197 N----VKSKIGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKS 252

Query: 694 KKVDI-SKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAK 736
           +K+D   +V SK GS  NI H PGGG+ KIE+ KL F+E A+AK
Sbjct: 253 EKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAK 296



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 36/132 (27%), Positives = 56/132 (42%), Gaps = 16/132 (12%)

Query: 340 TPQKMTEKSESKTPGEGKK----EDKSRMAEP-------MKGYMRPTKSRGLTPLLPKST 388
           T  +M  KS+  T  + KK    + K+++A P        KG    T+    TP  PK+ 
Sbjct: 65  TQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTP 124

Query: 389 IQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTS 448
               E  K    +G + P  G P   GT    +  P+   PP+ E K   +  T P   S
Sbjct: 125 PSSGEPPKSGDRSGYSSP--GSP---GTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPS 179

Query: 449 TSKAKTQPTSLP 460
           ++K++ Q   +P
Sbjct: 180 SAKSRLQTAPVP 191



 Score = 35.0 bits (79), Expect = 0.28
 Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 10/114 (8%)

Query: 415 GTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQ--PAPTTIGGLN 472
           GTG+D       +     + KTK +AT + A     K +   T +P +  PAP T     
Sbjct: 76  GTGSD------DKKAKGADGKTK-IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSG 128

Query: 473 KKPMSL-ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSK 525
           + P S   SG      P  P   S  PS+      +PK +A  + P K  S +K
Sbjct: 129 EPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK 182


>gi|6754638 microtubule-associated protein tau isoform 2 [Homo
           sapiens]
          Length = 441

 Score =  145 bits (366), Expect = 1e-34
 Identities = 109/342 (31%), Positives = 153/342 (44%), Gaps = 61/342 (17%)

Query: 467 TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSK- 525
           T  GL + P+   +      P    + A + P+   ++DV   P+ D  AP K+A+    
Sbjct: 39  TDAGLKESPLQTPTEDGSEEPGSETSDAKSTPT---AEDVTA-PLVDEGAPGKQAAAQPH 94

Query: 526 ---PASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVK 582
              P    A  +G   T ++          +   S     T    K    K +G   + K
Sbjct: 95  TEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDK----KAKGADGKTK 150

Query: 583 KMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVP--------SRVKATPMPSRPS 634
             T +       + ++ +T    KT     T P++G  P        S   +   P   S
Sbjct: 151 IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRS 210

Query: 635 TTPFIDKKPTS---------AKPSSTTPRLSRLATN-TSAPDLKNVRSKVGSTENIKHQP 684
            TP +   PT            P S +   SRL T     PDLKNV+SK+GSTEN+KHQP
Sbjct: 211 RTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 270

Query: 685 GGGRVQIQNKKVDISKVSSKCGSKANIKH------------------------------- 713
           GGG+VQI NKK+D+S V SKCGSK NIKH                               
Sbjct: 271 GGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHH 330

Query: 714 KPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 755
           KPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG  K E
Sbjct: 331 KPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 372


>gi|178557736 microtubule-associated protein tau isoform 5 [Homo
           sapiens]
          Length = 412

 Score =  142 bits (357), Expect = 2e-33
 Identities = 105/309 (33%), Positives = 140/309 (45%), Gaps = 64/309 (20%)

Query: 489 KRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSG---------SKST 539
           + P   ++     P+ + +   I D  + E  A+     +   S+S          +K  
Sbjct: 57  EEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGA 116

Query: 540 QTVAKTTTAAAVASTGPSSRSPSTLLPKK-PTAIKTEGKPAEVKKMTAKSVPADLSRPKS 598
               K  T    A  G   ++ +T +P K P A KT     E  K   +S     S P S
Sbjct: 117 DGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRS---GYSSPGS 173

Query: 599 TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 658
             T   +  T    T P        V  TP            K P+SAK        SRL
Sbjct: 174 PGTPGSRSRTPSLPTPPTREPKKVAVVRTP-----------PKSPSSAK--------SRL 214

Query: 659 ATN-TSAPDLKNVRSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSKANIKH---- 713
            T     PDLKNV+SK+GSTEN+KHQPGGG+VQI NKK+D+S V SKCGSK NIKH    
Sbjct: 215 QTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGG 274

Query: 714 ---------------------------KPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL 746
                                      KPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+
Sbjct: 275 GSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHV 334

Query: 747 PAGGAVKTE 755
           P GG  K E
Sbjct: 335 PGGGNKKIE 343


>gi|8400711 microtubule-associated protein tau isoform 3 [Homo
           sapiens]
          Length = 383

 Score =  141 bits (355), Expect = 3e-33
 Identities = 97/253 (38%), Positives = 122/253 (48%), Gaps = 55/253 (21%)

Query: 536 SKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKK-PTAIKTEGKPAEVKKMTAKSVPADLS 594
           +K      K  T    A  G   ++ +T +P K P A KT     E  K   +S     S
Sbjct: 84  AKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRS---GYS 140

Query: 595 RPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPR 654
            P S  T   +  T    T P        V  TP            K P+SAK       
Sbjct: 141 SPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP-----------PKSPSSAK------- 182

Query: 655 LSRLATN-TSAPDLKNVRSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSKANIKH 713
            SRL T     PDLKNV+SK+GSTEN+KHQPGGG+VQI NKK+D+S V SKCGSK NIKH
Sbjct: 183 -SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKH 241

Query: 714 -------------------------------KPGGGDVKIESQKLNFKEKAQAKVGSLDN 742
                                          KPGGG V+++S+KL+FK++ Q+K+GSLDN
Sbjct: 242 VPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDN 301

Query: 743 VGHLPAGGAVKTE 755
           + H+P GG  K E
Sbjct: 302 ITHVPGGGNKKIE 314



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 76/305 (24%), Positives = 116/305 (38%), Gaps = 56/305 (18%)

Query: 415 GTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQ--PAPTTIGGLN 472
           GTG+D       +     + KTK +AT + A     K +   T +P +  PAP T     
Sbjct: 76  GTGSD------DKKAKGADGKTK-IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSG 128

Query: 473 KKPMSL-ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP--ASA 529
           + P S   SG      P  P   S  PS+      +PK +A  + P K  S +K    +A
Sbjct: 129 EPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTA 188

Query: 530 PASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSV 589
           P      K+ +        + + ST      P              GK   + K      
Sbjct: 189 PVPMPDLKNVK--------SKIGSTENLKHQPG------------GGKVQIINK------ 222

Query: 590 PADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPS 649
             DLS  +S   S         G   +  +V   V  + + S+  +   I  KP   +  
Sbjct: 223 KLDLSNVQSKCGSKDNIKHVPGG--GSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVE 280

Query: 650 STTPRLSRLATNTSAPDLKN-VRSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSK 708
             + +L          D K+ V+SK+GS +NI H PGGG     NKK++  K++ +  +K
Sbjct: 281 VKSEKL----------DFKDRVQSKIGSLDNITHVPGGG-----NKKIETHKLTFRENAK 325

Query: 709 ANIKH 713
           A   H
Sbjct: 326 AKTDH 330



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 36/132 (27%), Positives = 56/132 (42%), Gaps = 16/132 (12%)

Query: 340 TPQKMTEKSESKTPGEGKK----EDKSRMAEP-------MKGYMRPTKSRGLTPLLPKST 388
           T  +M  KS+  T  + KK    + K+++A P        KG    T+    TP  PK+ 
Sbjct: 65  TQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTP 124

Query: 389 IQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTS 448
               E  K    +G + P  G P   GT    +  P+   PP+ E K   +  T P   S
Sbjct: 125 PSSGEPPKSGDRSGYSSP--GSP---GTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPS 179

Query: 449 TSKAKTQPTSLP 460
           ++K++ Q   +P
Sbjct: 180 SAKSRLQTAPVP 191


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 95.5 bits (236), Expect = 2e-19
 Identities = 146/584 (25%), Positives = 213/584 (36%), Gaps = 50/584 (8%)

Query: 100 PKGPSAVVPSTSTGGVALP----ITTAIETVNIHGDHSLKNKAELADSMKNEAGIDEGHV 155
           P G S  + ST+      P        IE+  I  +HS+    E + S  + +       
Sbjct: 81  PSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRK 140

Query: 156 IGESESVHSGASKHSVEKVTELAKGHL----LPGVPVEDQSLPGEARALEGYADRGNFPA 211
           I  S++  +        KV +  K        P  PV D++  G         D G+F  
Sbjct: 141 IKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG--------LDNGDFKV 192

Query: 212 HPVNEEKETKEGSVAVQIPDLLEDKAQKLSFCEDQNAQDRNSKGSDSLNKKVDLTLLSPK 271
                +  T + +     P +   K          N+ D + + S ++NK+  +      
Sbjct: 193 --TTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNS-DTSKETSLTVNKETTVETKETT 249

Query: 272 SENDKLKEISLACKITELESVSLPTPEIQSDFLHSKVEAPPSEVADTLVIMTASKGVRLP 331
           + N +          +  E+ S+     +     SKV A P+  A+T      +KG  L 
Sbjct: 250 TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAET-----TTKGPALT 304

Query: 332 EPKDKILETPQKMTEKSESKTPGEGKKED-KSRMAEPMKGYMRPTKSRGLTPLLPKSTIQ 390
            PK+    TP++      S TP E      KS    P +     TKS   TP  P  T  
Sbjct: 305 TPKEPTPTTPKEPA----STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTT 360

Query: 391 EQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTS-- 448
           ++      K       +E  P    T +  TTP  KE  P+  KK  P    +PA T+  
Sbjct: 361 KEPAPTTPKEPAPTTTKEPAPTT--TKSAPTTP--KEPAPTTPKKPAPTTPKEPAPTTPK 416

Query: 449 --TSKAKTQPTSLPKQPAPTT----IGGLNKKPMSLASGLVPAAPPKRPAVASAR-PSIL 501
             T     +P    K+PAPTT         KKP            PK PA  + + PS  
Sbjct: 417 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 476

Query: 502 PSKDVKPKPIADAKAPEKRASPSKPASAPAS-RSGSKSTQTVAKTTTAAAVASTGPSSRS 560
             K+  P     A    K  +P+   SAP + +  S +T      TT    A T P   +
Sbjct: 477 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 536

Query: 561 PSTLLPKKPTAIKTEGKPAEVKKM--TAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAG 618
           P+T     PT  K E  P   KK   T    PA  + PK T+ ++ KK T  +    A  
Sbjct: 537 PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAPTT-PKETAPTTPKKLTPTTPEKLAPT 594

Query: 619 VVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNT 662
                   TP    P TTP      T  +P+ TTP+ +  A NT
Sbjct: 595 TPEKPAPTTPEELAP-TTPEEPTPTTPEEPAPTTPKAA--APNT 635



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 150/717 (20%), Positives = 233/717 (32%), Gaps = 73/717 (10%)

Query: 48  EKLPTPTPQVVKEGDSFPDTLAKNGQEIAPAQISKSLMVDNYTKDGVPGQERPKGPSAVV 107
           +K PTP P VV E  S  D    NG        + +   +  +        +P  P   +
Sbjct: 168 KKKPTPKPPVVDEAGSGLD----NGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSL 223

Query: 108 PSTSTGGVALPITTAIETVNIHGDHSLKNKAELADSMKNEAGIDEGHVIGESESVHSGAS 167
           P  S       +T   ET     + +  NK    D  +      E   I ++ +     +
Sbjct: 224 PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 283

Query: 168 KHSVEKVTELA----KGHLL-------PGVPVEDQSLPGEARALEGYADRGNFPAHPVNE 216
              + K T  A    KG  L       P  P E  S   +             P  P   
Sbjct: 284 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 343

Query: 217 EKETKEGSVAVQIPDLLEDKAQKLSFCEDQNAQDRNSKGSDSLNKKVDLTLLSPKSENDK 276
             ++   +     P   ++ A        + A     + + +  K    T   P     K
Sbjct: 344 TTKSAPTTPKEPAPTTTKEPAPTTP---KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 400

Query: 277 LKEISLACKITELESVSLPTPEIQSDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDK 336
            K      K     +   PTP    +   +  E  P+   +     TA K      PK+ 
Sbjct: 401 -KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP--TAPKKPAPTTPKEP 457

Query: 337 ILETPQK----MTEKSESKTPGE-GKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQE 391
              TP++     T++    TP E      KS      +     TKS   TP  P  T  +
Sbjct: 458 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 517

Query: 392 QERHKQLKSAGIARPEEGRPVVSGTGNDITTP----PNKELPPSPEKKTKPLATTQPAKT 447
           +      K      P++  P         TTP    P     P+P    +P  TT     
Sbjct: 518 EPAPTTPKEPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 576

Query: 448 STSKAKTQPT-------SLPKQPAPTTIGGLNKKPMSLASGLVPAAP------------P 488
            T+  K  PT       + P++PAPTT   L        +   P  P            P
Sbjct: 577 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 636

Query: 489 KRPAVASAR---------PSILPSKDVKP-KPIADAKAPEKRASPSKPASAPASRSGSKS 538
           K PA  + +         P+    K+  P  P   A    K  +P+ P   PA +  + +
Sbjct: 637 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP-KKPAPKELAPT 695

Query: 539 TQTVAKTTTAAAVASTGPSSRSPST------LLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
           T     +TT    A T P   +P+T        PK+P     +G      K  A + P  
Sbjct: 696 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 755

Query: 593 LSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTT 652
              PK  + ++ K  T+ +   PA          TP    P TTP   KKP    P +  
Sbjct: 756 -PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP-TTP---KKPAPTTPETPP 810

Query: 653 PRLSRLATNTSAPDLKNV-RSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSK 708
           P  S ++T T+  +   + +S   ST  +  +P    ++   K+  +    +   +K
Sbjct: 811 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK 867



 Score = 70.1 bits (170), Expect = 8e-12
 Identities = 95/376 (25%), Positives = 151/376 (40%), Gaps = 58/376 (15%)

Query: 323  TASKGVRLPEPKDKILETPQKMTEKSESKT-PGEGKKEDKSRMAEPMKGYMRPTKSRGLT 381
            T  KG     PK+    TP++    +   T P   K+   +   +P    + PT ++G  
Sbjct: 711  TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG-- 768

Query: 382  PLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLAT 441
               P ST  ++      K      P+E  P          T P K  P +PE  T P  T
Sbjct: 769  ---PTSTTSDKPAPTTPKETAPTTPKEPAP----------TTPKKPAPTTPE--TPPPTT 813

Query: 442  TQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAA---PPKRPAVASARP 498
            ++ +  +T+K   +PT++ K P  +T          L++   P A    PK P V    P
Sbjct: 814  SEVSTPTTTK---EPTTIHKSPDEST--------PELSAEPTPKALENSPKEPGV----P 858

Query: 499  SILPSKDVKPKPIADAK-APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPS 557
            +       KP+    AK    +R   + P +  A+   +K T T  + TT + + +T   
Sbjct: 859  TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ 918

Query: 558  SRSPST--LLPKKPTAIKTEGKPAEV----KKMTAKSV---PADLSRPKSTSTSSMKKTT 608
              S +T    P K T +KT     +V    K +T   +   P + ++PK  +T+S  K T
Sbjct: 919  VTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNS--KAT 976

Query: 609  TLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDK---KPTSAKPSSTTPRLSRLATNTSAP 665
            T     P     P +  +T    +P T P + K    PT  K +ST P L+   T+  A 
Sbjct: 977  TPKPQKPTKA--PKKPTST---KKPKTMPRVRKPKTTPTPRKMTSTMPELN--PTSRIAE 1029

Query: 666  DLKNVRSKVGSTENIK 681
             +    ++   T N K
Sbjct: 1030 AMLQTTTRPNQTPNSK 1045



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 105/427 (24%), Positives = 152/427 (35%), Gaps = 55/427 (12%)

Query: 266 TLLSPKSENDK-LKEISLACKITELESVSLPTPEIQSD-----------FLHSKVEAPPS 313
           T  SPK  N K  K++  + +ITE  SVS       S               SK  A   
Sbjct: 92  TKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANR 151

Query: 314 EVADTLVIMTASKG--VRLPEPKDKILETPQKMTEKSESK--TPGEGKKEDKSRMAEPMK 369
           E+   L +    K    + P PK  +++      +  + K  TP     +       P  
Sbjct: 152 ELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKI 211

Query: 370 GYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGND--ITTPPNKE 427
              +P   R   P LP ++   +E    +        +E       T  D    T   KE
Sbjct: 212 TTAKPINPR---PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKE 268

Query: 428 LPPSPEKKTKPLATT-----QPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGL 482
                +   K LA T     +P   + +  K    + PK+P PTT     K+P S     
Sbjct: 269 TQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT----PKEPASTT--- 321

Query: 483 VPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTV 542
                PK P   + + +  P+   +P P     AP    +P +PA          + +  
Sbjct: 322 -----PKEPTPTTIKSA--PTTPKEPAPTTTKSAP---TTPKEPAPTTTKEPAPTTPKEP 371

Query: 543 AKTTTAAAVASTGPSS----RSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS 598
           A TTT     +T  S+    + P+   PKKP A  T  +PA     T    P   +  + 
Sbjct: 372 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKP-APTTPKEPAP----TTPKEPTPTTPKEP 426

Query: 599 TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 658
             T+     TT    AP A   P+    TP    P TTP      T+ +PS TTP+    
Sbjct: 427 APTTKEPAPTTPKEPAPTAPKKPA--PTTPKEPAP-TTPKEPAPTTTKEPSPTTPKEPAP 483

Query: 659 ATNTSAP 665
            T  SAP
Sbjct: 484 TTTKSAP 490



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 88/395 (22%), Positives = 143/395 (36%), Gaps = 35/395 (8%)

Query: 295 PTPEIQSDFLHSKVEAP----PSEVADTLVIMTASKGVRLPEP---KDKILETPQKMTEK 347
           P P    +   +  E P    P E A T     A    + P P   K+    TP++    
Sbjct: 599 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 658

Query: 348 SESKT-PGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLL---PKSTIQEQERHKQLKSAGI 403
           +  +T P   K    + + EP     +    + L P     P ST  ++      K    
Sbjct: 659 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 718

Query: 404 ARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQP 463
             P+E  P         TTP  KE  P+  K T P    +PA T+  K        PK+ 
Sbjct: 719 TTPKEPAP---------TTP--KEPAPTTPKGTAPTTLKEPAPTTPKKPA------PKEL 761

Query: 464 APTTIGG----LNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEK 519
           APTT  G     + KP            PK PA  + +     + +  P   ++   P  
Sbjct: 762 APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTT 821

Query: 520 RASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPA 579
              P+    +P   +   S +   K    +      P++++P+   P+  T  K +    
Sbjct: 822 TKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 881

Query: 580 EVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVK-ATPMPSRPSTTPF 638
           ++ + T ++  A     K T+T++ +KTT    TA    V  +  +  TP       T  
Sbjct: 882 DL-RTTPETTTAAPKMTKETATTT-EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTT 939

Query: 639 IDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSK 673
           +  K T+ K + TT  +      T+ P  +   SK
Sbjct: 940 LAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSK 974



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 85/362 (23%), Positives = 126/362 (34%), Gaps = 42/362 (11%)

Query: 312  PSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEKSESK-TPGEGKKEDKSRMAEPMKG 370
            P   A T +   A    + P PK+    T +  T  +  K  P   K+   +   EP   
Sbjct: 737  PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP- 795

Query: 371  YMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIAR--PEEGRPVVSGTGNDITTPPNKEL 428
               P K    TP  P  T  E       K        P+E  P +S        P  K L
Sbjct: 796  -TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE------PTPKAL 848

Query: 429  PPSPEKK----TKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVP 484
              SP++     TK  A T+P  T+T+K KT    L   P  TT      K  +  +    
Sbjct: 849  ENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTT---E 905

Query: 485  AAPPKRPAVASARPSILPSKDVKPKPIADAK----APE-----KRASPSKPASAPASRSG 535
                 +    + + +   ++D  P  I   K    AP+     K  + ++  + P   + 
Sbjct: 906  KTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAK 965

Query: 536  SKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLS- 594
             K   T +K TT        P  + P T  PKKPT+ K       V+K      P  ++ 
Sbjct: 966  PKDRATNSKATT--------PKPQKP-TKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS 1016

Query: 595  -----RPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPS 649
                  P S    +M +TTT     P + +V    K+         TP +  +P    P 
Sbjct: 1017 TMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPE 1076

Query: 650  ST 651
             T
Sbjct: 1077 VT 1078



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 75/354 (21%), Positives = 123/354 (34%), Gaps = 63/354 (17%)

Query: 306 SKVEAPPSEVADTLVIMTASKGVRLPEPKD--KILETPQKMTEKSESKTPGEGKKEDKSR 363
           S  +APP   A   +  T  +  + P  K   K++E+ +   E S S+          S 
Sbjct: 74  SSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSS 133

Query: 364 MAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTP 423
            +  ++       S     L  K  +++ ++++  K     +P    PVV   G+ +   
Sbjct: 134 SSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKK-----KPTPKPPVVDEAGSGLDNG 188

Query: 424 PNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLV 483
             K   P         +TTQ  K STS            P  TT   +N +P        
Sbjct: 189 DFKVTTPDT-------STTQHNKVSTS------------PKITTAKPINPRP-------- 221

Query: 484 PAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVA 543
            + PP          ++     V+ K               K  SA       K TQ++ 
Sbjct: 222 -SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSA-------KETQSIE 273

Query: 544 KTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSS 603
           KT+         P+S+  +   PK  T  K    PA    +T    P   +  +  ST+ 
Sbjct: 274 KTSAK----DLAPTSKVLAKPTPKAETTTKG---PA----LTTPKEPTPTTPKEPASTTP 322

Query: 604 MKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKP---TSAKPSSTTPR 654
            + T T   +AP            P P+   + P   K+P   T+ +P+ TTP+
Sbjct: 323 KEPTPTTIKSAPTT-------PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 369


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 95.5 bits (236), Expect = 2e-19
 Identities = 146/584 (25%), Positives = 213/584 (36%), Gaps = 50/584 (8%)

Query: 100 PKGPSAVVPSTSTGGVALP----ITTAIETVNIHGDHSLKNKAELADSMKNEAGIDEGHV 155
           P G S  + ST+      P        IE+  I  +HS+    E + S  + +       
Sbjct: 122 PSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRK 181

Query: 156 IGESESVHSGASKHSVEKVTELAKGHL----LPGVPVEDQSLPGEARALEGYADRGNFPA 211
           I  S++  +        KV +  K        P  PV D++  G         D G+F  
Sbjct: 182 IKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG--------LDNGDFKV 233

Query: 212 HPVNEEKETKEGSVAVQIPDLLEDKAQKLSFCEDQNAQDRNSKGSDSLNKKVDLTLLSPK 271
                +  T + +     P +   K          N+ D + + S ++NK+  +      
Sbjct: 234 --TTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNS-DTSKETSLTVNKETTVETKETT 290

Query: 272 SENDKLKEISLACKITELESVSLPTPEIQSDFLHSKVEAPPSEVADTLVIMTASKGVRLP 331
           + N +          +  E+ S+     +     SKV A P+  A+T      +KG  L 
Sbjct: 291 TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAET-----TTKGPALT 345

Query: 332 EPKDKILETPQKMTEKSESKTPGEGKKED-KSRMAEPMKGYMRPTKSRGLTPLLPKSTIQ 390
            PK+    TP++      S TP E      KS    P +     TKS   TP  P  T  
Sbjct: 346 TPKEPTPTTPKEPA----STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTT 401

Query: 391 EQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTS-- 448
           ++      K       +E  P    T +  TTP  KE  P+  KK  P    +PA T+  
Sbjct: 402 KEPAPTTPKEPAPTTTKEPAPTT--TKSAPTTP--KEPAPTTPKKPAPTTPKEPAPTTPK 457

Query: 449 --TSKAKTQPTSLPKQPAPTT----IGGLNKKPMSLASGLVPAAPPKRPAVASAR-PSIL 501
             T     +P    K+PAPTT         KKP            PK PA  + + PS  
Sbjct: 458 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 517

Query: 502 PSKDVKPKPIADAKAPEKRASPSKPASAPAS-RSGSKSTQTVAKTTTAAAVASTGPSSRS 560
             K+  P     A    K  +P+   SAP + +  S +T      TT    A T P   +
Sbjct: 518 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 577

Query: 561 PSTLLPKKPTAIKTEGKPAEVKKM--TAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAG 618
           P+T     PT  K E  P   KK   T    PA  + PK T+ ++ KK T  +    A  
Sbjct: 578 PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAPTT-PKETAPTTPKKLTPTTPEKLAPT 635

Query: 619 VVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNT 662
                   TP    P TTP      T  +P+ TTP+ +  A NT
Sbjct: 636 TPEKPAPTTPEELAP-TTPEEPTPTTPEEPAPTTPKAA--APNT 676



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 150/717 (20%), Positives = 233/717 (32%), Gaps = 73/717 (10%)

Query: 48  EKLPTPTPQVVKEGDSFPDTLAKNGQEIAPAQISKSLMVDNYTKDGVPGQERPKGPSAVV 107
           +K PTP P VV E  S  D    NG        + +   +  +        +P  P   +
Sbjct: 209 KKKPTPKPPVVDEAGSGLD----NGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSL 264

Query: 108 PSTSTGGVALPITTAIETVNIHGDHSLKNKAELADSMKNEAGIDEGHVIGESESVHSGAS 167
           P  S       +T   ET     + +  NK    D  +      E   I ++ +     +
Sbjct: 265 PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 324

Query: 168 KHSVEKVTELA----KGHLL-------PGVPVEDQSLPGEARALEGYADRGNFPAHPVNE 216
              + K T  A    KG  L       P  P E  S   +             P  P   
Sbjct: 325 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 384

Query: 217 EKETKEGSVAVQIPDLLEDKAQKLSFCEDQNAQDRNSKGSDSLNKKVDLTLLSPKSENDK 276
             ++   +     P   ++ A        + A     + + +  K    T   P     K
Sbjct: 385 TTKSAPTTPKEPAPTTTKEPAPTTP---KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 441

Query: 277 LKEISLACKITELESVSLPTPEIQSDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDK 336
            K      K     +   PTP    +   +  E  P+   +     TA K      PK+ 
Sbjct: 442 -KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP--TAPKKPAPTTPKEP 498

Query: 337 ILETPQK----MTEKSESKTPGE-GKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQE 391
              TP++     T++    TP E      KS      +     TKS   TP  P  T  +
Sbjct: 499 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 558

Query: 392 QERHKQLKSAGIARPEEGRPVVSGTGNDITTP----PNKELPPSPEKKTKPLATTQPAKT 447
           +      K      P++  P         TTP    P     P+P    +P  TT     
Sbjct: 559 EPAPTTPKEPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 617

Query: 448 STSKAKTQPT-------SLPKQPAPTTIGGLNKKPMSLASGLVPAAP------------P 488
            T+  K  PT       + P++PAPTT   L        +   P  P            P
Sbjct: 618 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 677

Query: 489 KRPAVASAR---------PSILPSKDVKP-KPIADAKAPEKRASPSKPASAPASRSGSKS 538
           K PA  + +         P+    K+  P  P   A    K  +P+ P   PA +  + +
Sbjct: 678 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP-KKPAPKELAPT 736

Query: 539 TQTVAKTTTAAAVASTGPSSRSPST------LLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
           T     +TT    A T P   +P+T        PK+P     +G      K  A + P  
Sbjct: 737 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 796

Query: 593 LSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTT 652
              PK  + ++ K  T+ +   PA          TP    P TTP   KKP    P +  
Sbjct: 797 -PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP-TTP---KKPAPTTPETPP 851

Query: 653 PRLSRLATNTSAPDLKNV-RSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSK 708
           P  S ++T T+  +   + +S   ST  +  +P    ++   K+  +    +   +K
Sbjct: 852 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK 908



 Score = 70.1 bits (170), Expect = 8e-12
 Identities = 95/376 (25%), Positives = 151/376 (40%), Gaps = 58/376 (15%)

Query: 323  TASKGVRLPEPKDKILETPQKMTEKSESKT-PGEGKKEDKSRMAEPMKGYMRPTKSRGLT 381
            T  KG     PK+    TP++    +   T P   K+   +   +P    + PT ++G  
Sbjct: 752  TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG-- 809

Query: 382  PLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLAT 441
               P ST  ++      K      P+E  P          T P K  P +PE  T P  T
Sbjct: 810  ---PTSTTSDKPAPTTPKETAPTTPKEPAP----------TTPKKPAPTTPE--TPPPTT 854

Query: 442  TQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAA---PPKRPAVASARP 498
            ++ +  +T+K   +PT++ K P  +T          L++   P A    PK P V    P
Sbjct: 855  SEVSTPTTTK---EPTTIHKSPDEST--------PELSAEPTPKALENSPKEPGV----P 899

Query: 499  SILPSKDVKPKPIADAK-APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPS 557
            +       KP+    AK    +R   + P +  A+   +K T T  + TT + + +T   
Sbjct: 900  TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ 959

Query: 558  SRSPST--LLPKKPTAIKTEGKPAEV----KKMTAKSV---PADLSRPKSTSTSSMKKTT 608
              S +T    P K T +KT     +V    K +T   +   P + ++PK  +T+S  K T
Sbjct: 960  VTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNS--KAT 1017

Query: 609  TLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDK---KPTSAKPSSTTPRLSRLATNTSAP 665
            T     P     P +  +T    +P T P + K    PT  K +ST P L+   T+  A 
Sbjct: 1018 TPKPQKPTKA--PKKPTST---KKPKTMPRVRKPKTTPTPRKMTSTMPELN--PTSRIAE 1070

Query: 666  DLKNVRSKVGSTENIK 681
             +    ++   T N K
Sbjct: 1071 AMLQTTTRPNQTPNSK 1086



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 105/427 (24%), Positives = 152/427 (35%), Gaps = 55/427 (12%)

Query: 266 TLLSPKSENDK-LKEISLACKITELESVSLPTPEIQSD-----------FLHSKVEAPPS 313
           T  SPK  N K  K++  + +ITE  SVS       S               SK  A   
Sbjct: 133 TKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANR 192

Query: 314 EVADTLVIMTASKG--VRLPEPKDKILETPQKMTEKSESK--TPGEGKKEDKSRMAEPMK 369
           E+   L +    K    + P PK  +++      +  + K  TP     +       P  
Sbjct: 193 ELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKI 252

Query: 370 GYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGND--ITTPPNKE 427
              +P   R   P LP ++   +E    +        +E       T  D    T   KE
Sbjct: 253 TTAKPINPR---PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKE 309

Query: 428 LPPSPEKKTKPLATT-----QPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGL 482
                +   K LA T     +P   + +  K    + PK+P PTT     K+P S     
Sbjct: 310 TQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT----PKEPASTT--- 362

Query: 483 VPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTV 542
                PK P   + + +  P+   +P P     AP    +P +PA          + +  
Sbjct: 363 -----PKEPTPTTIKSA--PTTPKEPAPTTTKSAP---TTPKEPAPTTTKEPAPTTPKEP 412

Query: 543 AKTTTAAAVASTGPSS----RSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS 598
           A TTT     +T  S+    + P+   PKKP A  T  +PA     T    P   +  + 
Sbjct: 413 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKP-APTTPKEPAP----TTPKEPTPTTPKEP 467

Query: 599 TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 658
             T+     TT    AP A   P+    TP    P TTP      T+ +PS TTP+    
Sbjct: 468 APTTKEPAPTTPKEPAPTAPKKPA--PTTPKEPAP-TTPKEPAPTTTKEPSPTTPKEPAP 524

Query: 659 ATNTSAP 665
            T  SAP
Sbjct: 525 TTTKSAP 531



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 88/395 (22%), Positives = 143/395 (36%), Gaps = 35/395 (8%)

Query: 295  PTPEIQSDFLHSKVEAP----PSEVADTLVIMTASKGVRLPEP---KDKILETPQKMTEK 347
            P P    +   +  E P    P E A T     A    + P P   K+    TP++    
Sbjct: 640  PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 699

Query: 348  SESKT-PGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLL---PKSTIQEQERHKQLKSAGI 403
            +  +T P   K    + + EP     +    + L P     P ST  ++      K    
Sbjct: 700  TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 759

Query: 404  ARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQP 463
              P+E  P         TTP  KE  P+  K T P    +PA T+  K        PK+ 
Sbjct: 760  TTPKEPAP---------TTP--KEPAPTTPKGTAPTTLKEPAPTTPKKPA------PKEL 802

Query: 464  APTTIGG----LNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEK 519
            APTT  G     + KP            PK PA  + +     + +  P   ++   P  
Sbjct: 803  APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTT 862

Query: 520  RASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPA 579
               P+    +P   +   S +   K    +      P++++P+   P+  T  K +    
Sbjct: 863  TKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 922

Query: 580  EVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVK-ATPMPSRPSTTPF 638
            ++ + T ++  A     K T+T++ +KTT    TA    V  +  +  TP       T  
Sbjct: 923  DL-RTTPETTTAAPKMTKETATTT-EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTT 980

Query: 639  IDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSK 673
            +  K T+ K + TT  +      T+ P  +   SK
Sbjct: 981  LAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSK 1015



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 85/362 (23%), Positives = 126/362 (34%), Gaps = 42/362 (11%)

Query: 312  PSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEKSESK-TPGEGKKEDKSRMAEPMKG 370
            P   A T +   A    + P PK+    T +  T  +  K  P   K+   +   EP   
Sbjct: 778  PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP- 836

Query: 371  YMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIAR--PEEGRPVVSGTGNDITTPPNKEL 428
               P K    TP  P  T  E       K        P+E  P +S        P  K L
Sbjct: 837  -TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE------PTPKAL 889

Query: 429  PPSPEKK----TKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVP 484
              SP++     TK  A T+P  T+T+K KT    L   P  TT      K  +  +    
Sbjct: 890  ENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTT---E 946

Query: 485  AAPPKRPAVASARPSILPSKDVKPKPIADAK----APE-----KRASPSKPASAPASRSG 535
                 +    + + +   ++D  P  I   K    AP+     K  + ++  + P   + 
Sbjct: 947  KTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAK 1006

Query: 536  SKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLS- 594
             K   T +K TT        P  + P T  PKKPT+ K       V+K      P  ++ 
Sbjct: 1007 PKDRATNSKATT--------PKPQKP-TKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS 1057

Query: 595  -----RPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPS 649
                  P S    +M +TTT     P + +V    K+         TP +  +P    P 
Sbjct: 1058 TMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPE 1117

Query: 650  ST 651
             T
Sbjct: 1118 VT 1119



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 75/354 (21%), Positives = 123/354 (34%), Gaps = 63/354 (17%)

Query: 306 SKVEAPPSEVADTLVIMTASKGVRLPEPKD--KILETPQKMTEKSESKTPGEGKKEDKSR 363
           S  +APP   A   +  T  +  + P  K   K++E+ +   E S S+          S 
Sbjct: 115 SSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSS 174

Query: 364 MAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTP 423
            +  ++       S     L  K  +++ ++++  K     +P    PVV   G+ +   
Sbjct: 175 SSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKK-----KPTPKPPVVDEAGSGLDNG 229

Query: 424 PNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLV 483
             K   P         +TTQ  K STS            P  TT   +N +P        
Sbjct: 230 DFKVTTPDT-------STTQHNKVSTS------------PKITTAKPINPRP-------- 262

Query: 484 PAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVA 543
            + PP          ++     V+ K               K  SA       K TQ++ 
Sbjct: 263 -SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSA-------KETQSIE 314

Query: 544 KTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSS 603
           KT+         P+S+  +   PK  T  K    PA    +T    P   +  +  ST+ 
Sbjct: 315 KTSAK----DLAPTSKVLAKPTPKAETTTKG---PA----LTTPKEPTPTTPKEPASTTP 363

Query: 604 MKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKP---TSAKPSSTTPR 654
            + T T   +AP            P P+   + P   K+P   T+ +P+ TTP+
Sbjct: 364 KEPTPTTIKSAPTT-------PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 410


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 91.7 bits (226), Expect = 3e-18
 Identities = 107/417 (25%), Positives = 156/417 (37%), Gaps = 66/417 (15%)

Query: 264 DLTLLSPKSENDKLKEISLACKITELESVSLPTPEIQSDFLHSKVEAPPSEVADTLVIMT 323
           D  + +P +   +  ++S + KIT  + ++ P P +           PP+  +DT     
Sbjct: 96  DFKVTTPDTSTTQHNKVSTSPKITTAKPIN-PRPSL-----------PPN--SDT----- 136

Query: 324 ASKGVRLPEPKDKILETPQKMTEKSESKTPGEGK-----------KEDKSRMAEPMKGYM 372
            SK   L   K+  +ET +  T   ++ T G+ K           K     +A   K   
Sbjct: 137 -SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA 195

Query: 373 RPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSP 432
           +PT     T   P  T  ++      K      P+E  P        I + P     P+P
Sbjct: 196 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT------IKSAPTTPKEPAP 249

Query: 433 EK-KTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRP 491
              K+ P    +PA T+T +    PT+ PK+PAPTT     K+P    +   P  P K P
Sbjct: 250 TTTKSAPTTPKEPAPTTTKEPA--PTT-PKEPAPTT----TKEPAPTTTKSAPTTP-KEP 301

Query: 492 AVASARPSILPSKDVKPKPIADAKAPEKRASPSKPAS-APASRSGSKSTQTVAKTTTAAA 550
           A  +      P K     P   A    K  +P+ P   AP ++  + +T      T    
Sbjct: 302 APTT------PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 355

Query: 551 VASTGPSSRSPSTLLPKKPTAIKTEGK--PAEVKKMTAKSVPADLSRPKSTSTSSMKKT- 607
            A T P   +P+T     PT  K      P E    T KS P     P  T+T S   T 
Sbjct: 356 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 415

Query: 608 -----TTLSGTAPAAGVVPS-RVKATPMPSRPS----TTPFIDKKPTSAKPSSTTPR 654
                TT    AP     P+      P P+ P     TTP      T+ KP+ TTP+
Sbjct: 416 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 472



 Score = 91.3 bits (225), Expect = 3e-18
 Identities = 109/370 (29%), Positives = 144/370 (38%), Gaps = 31/370 (8%)

Query: 306 SKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEKSESKTPGEGKKED-KSRM 364
           SKV A P+  A+T      +KG  L  PK+    TP++      S TP E      KS  
Sbjct: 191 SKVLAKPTPKAET-----TTKGPALTTPKEPTPTTPKEPA----STTPKEPTPTTIKSAP 241

Query: 365 AEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPP 424
             P +     TKS   TP  P  T  ++      K       +E  P    T +  TTP 
Sbjct: 242 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT--TKSAPTTP- 298

Query: 425 NKELPPSPEKKTKPLATTQPAKTS----TSKAKTQPTSLPKQPAPTT----IGGLNKKPM 476
            KE  P+  KK  P    +PA T+    T     +P    K+PAPTT         KKP 
Sbjct: 299 -KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 357

Query: 477 SLASGLVPAAPPKRPAVASAR-PSILPSKDVKPKPIADAKAPEKRASPSKPASAPAS-RS 534
                      PK PA  + + PS    K+  P     A    K  +P+   SAP + + 
Sbjct: 358 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 417

Query: 535 GSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKM--TAKSVPAD 592
            S +T      TT    A T P   +P+T     PT  K E  P   KK   T    PA 
Sbjct: 418 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP 476

Query: 593 LSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTT 652
            + PK T+ ++ KK T  +    A          TP    P TTP      T  +P+ TT
Sbjct: 477 TT-PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-TTPEEPTPTTPEEPAPTT 534

Query: 653 PRLSRLATNT 662
           P+ +  A NT
Sbjct: 535 PKAA--APNT 542



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 150/717 (20%), Positives = 233/717 (32%), Gaps = 73/717 (10%)

Query: 48  EKLPTPTPQVVKEGDSFPDTLAKNGQEIAPAQISKSLMVDNYTKDGVPGQERPKGPSAVV 107
           +K PTP P VV E  S  D    NG        + +   +  +        +P  P   +
Sbjct: 75  KKKPTPKPPVVDEAGSGLD----NGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSL 130

Query: 108 PSTSTGGVALPITTAIETVNIHGDHSLKNKAELADSMKNEAGIDEGHVIGESESVHSGAS 167
           P  S       +T   ET     + +  NK    D  +      E   I ++ +     +
Sbjct: 131 PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 190

Query: 168 KHSVEKVTELA----KGHLL-------PGVPVEDQSLPGEARALEGYADRGNFPAHPVNE 216
              + K T  A    KG  L       P  P E  S   +             P  P   
Sbjct: 191 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 250

Query: 217 EKETKEGSVAVQIPDLLEDKAQKLSFCEDQNAQDRNSKGSDSLNKKVDLTLLSPKSENDK 276
             ++   +     P   ++ A        + A     + + +  K    T   P     K
Sbjct: 251 TTKSAPTTPKEPAPTTTKEPAPTTP---KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 307

Query: 277 LKEISLACKITELESVSLPTPEIQSDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDK 336
            K      K     +   PTP    +   +  E  P+   +     TA K      PK+ 
Sbjct: 308 -KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP--TAPKKPAPTTPKEP 364

Query: 337 ILETPQK----MTEKSESKTPGE-GKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQE 391
              TP++     T++    TP E      KS      +     TKS   TP  P  T  +
Sbjct: 365 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 424

Query: 392 QERHKQLKSAGIARPEEGRPVVSGTGNDITTP----PNKELPPSPEKKTKPLATTQPAKT 447
           +      K      P++  P         TTP    P     P+P    +P  TT     
Sbjct: 425 EPAPTTPKEPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 483

Query: 448 STSKAKTQPT-------SLPKQPAPTTIGGLNKKPMSLASGLVPAAP------------P 488
            T+  K  PT       + P++PAPTT   L        +   P  P            P
Sbjct: 484 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 543

Query: 489 KRPAVASAR---------PSILPSKDVKP-KPIADAKAPEKRASPSKPASAPASRSGSKS 538
           K PA  + +         P+    K+  P  P   A    K  +P+ P   PA +  + +
Sbjct: 544 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP-KKPAPKELAPT 602

Query: 539 TQTVAKTTTAAAVASTGPSSRSPST------LLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
           T     +TT    A T P   +P+T        PK+P     +G      K  A + P  
Sbjct: 603 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 662

Query: 593 LSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTT 652
              PK  + ++ K  T+ +   PA          TP    P TTP   KKP    P +  
Sbjct: 663 -PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP-TTP---KKPAPTTPETPP 717

Query: 653 PRLSRLATNTSAPDLKNV-RSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSK 708
           P  S ++T T+  +   + +S   ST  +  +P    ++   K+  +    +   +K
Sbjct: 718 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK 774



 Score = 70.1 bits (170), Expect = 8e-12
 Identities = 95/376 (25%), Positives = 151/376 (40%), Gaps = 58/376 (15%)

Query: 323 TASKGVRLPEPKDKILETPQKMTEKSESKT-PGEGKKEDKSRMAEPMKGYMRPTKSRGLT 381
           T  KG     PK+    TP++    +   T P   K+   +   +P    + PT ++G  
Sbjct: 618 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG-- 675

Query: 382 PLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLAT 441
              P ST  ++      K      P+E  P          T P K  P +PE  T P  T
Sbjct: 676 ---PTSTTSDKPAPTTPKETAPTTPKEPAP----------TTPKKPAPTTPE--TPPPTT 720

Query: 442 TQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAA---PPKRPAVASARP 498
           ++ +  +T+K   +PT++ K P  +T          L++   P A    PK P V    P
Sbjct: 721 SEVSTPTTTK---EPTTIHKSPDEST--------PELSAEPTPKALENSPKEPGV----P 765

Query: 499 SILPSKDVKPKPIADAK-APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPS 557
           +       KP+    AK    +R   + P +  A+   +K T T  + TT + + +T   
Sbjct: 766 TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ 825

Query: 558 SRSPST--LLPKKPTAIKTEGKPAEV----KKMTAKSV---PADLSRPKSTSTSSMKKTT 608
             S +T    P K T +KT     +V    K +T   +   P + ++PK  +T+S  K T
Sbjct: 826 VTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNS--KAT 883

Query: 609 TLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDK---KPTSAKPSSTTPRLSRLATNTSAP 665
           T     P     P +  +T    +P T P + K    PT  K +ST P L+   T+  A 
Sbjct: 884 TPKPQKPTKA--PKKPTST---KKPKTMPRVRKPKTTPTPRKMTSTMPELN--PTSRIAE 936

Query: 666 DLKNVRSKVGSTENIK 681
            +    ++   T N K
Sbjct: 937 AMLQTTTRPNQTPNSK 952



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 88/395 (22%), Positives = 143/395 (36%), Gaps = 35/395 (8%)

Query: 295 PTPEIQSDFLHSKVEAP----PSEVADTLVIMTASKGVRLPEP---KDKILETPQKMTEK 347
           P P    +   +  E P    P E A T     A    + P P   K+    TP++    
Sbjct: 506 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 565

Query: 348 SESKT-PGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLL---PKSTIQEQERHKQLKSAGI 403
           +  +T P   K    + + EP     +    + L P     P ST  ++      K    
Sbjct: 566 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 625

Query: 404 ARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQP 463
             P+E  P         TTP  KE  P+  K T P    +PA T+  K        PK+ 
Sbjct: 626 TTPKEPAP---------TTP--KEPAPTTPKGTAPTTLKEPAPTTPKKPA------PKEL 668

Query: 464 APTTIGG----LNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEK 519
           APTT  G     + KP            PK PA  + +     + +  P   ++   P  
Sbjct: 669 APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTT 728

Query: 520 RASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPA 579
              P+    +P   +   S +   K    +      P++++P+   P+  T  K +    
Sbjct: 729 TKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 788

Query: 580 EVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVK-ATPMPSRPSTTPF 638
           ++ + T ++  A     K T+T++ +KTT    TA    V  +  +  TP       T  
Sbjct: 789 DL-RTTPETTTAAPKMTKETATTT-EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTT 846

Query: 639 IDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSK 673
           +  K T+ K + TT  +      T+ P  +   SK
Sbjct: 847 LAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSK 881



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 90/366 (24%), Positives = 131/366 (35%), Gaps = 45/366 (12%)

Query: 313 SEVADTLVIMTASKGVRLPEPKDKILETPQKMTEKSESK--TPGEGKKEDKSRMAEPMKG 370
           +EV D     T  K    P PK  +++      +  + K  TP     +       P   
Sbjct: 64  AEVKDNKKNRTKKK----PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKIT 119

Query: 371 YMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGND--ITTPPNKEL 428
             +P   R   P LP ++   +E    +        +E       T  D    T   KE 
Sbjct: 120 TAKPINPR---PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKET 176

Query: 429 PPSPEKKTKPLATT-----QPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLV 483
               +   K LA T     +P   + +  K    + PK+P PTT     K+P S      
Sbjct: 177 QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT----PKEPASTT---- 228

Query: 484 PAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVA 543
               PK P   + + +  P+   +P P     AP    +P +PA          + +  A
Sbjct: 229 ----PKEPTPTTIKSA--PTTPKEPAPTTTKSAP---TTPKEPAPTTTKEPAPTTPKEPA 279

Query: 544 KTTTAAAVASTGPSS----RSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKST 599
            TTT     +T  S+    + P+   PKKP A  T  +PA     T    P   +  +  
Sbjct: 280 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKP-APTTPKEPAP----TTPKEPTPTTPKEPA 334

Query: 600 STSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLA 659
            T+     TT    AP A   P+    TP    P TTP      T+ +PS TTP+     
Sbjct: 335 PTTKEPAPTTPKEPAPTAPKKPA--PTTPKEPAP-TTPKEPAPTTTKEPSPTTPKEPAPT 391

Query: 660 TNTSAP 665
           T  SAP
Sbjct: 392 TTKSAP 397



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 85/362 (23%), Positives = 126/362 (34%), Gaps = 42/362 (11%)

Query: 312 PSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEKSESK-TPGEGKKEDKSRMAEPMKG 370
           P   A T +   A    + P PK+    T +  T  +  K  P   K+   +   EP   
Sbjct: 644 PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP- 702

Query: 371 YMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIAR--PEEGRPVVSGTGNDITTPPNKEL 428
              P K    TP  P  T  E       K        P+E  P +S        P  K L
Sbjct: 703 -TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE------PTPKAL 755

Query: 429 PPSPEKK----TKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVP 484
             SP++     TK  A T+P  T+T+K KT    L   P  TT      K  +  +    
Sbjct: 756 ENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTT---E 812

Query: 485 AAPPKRPAVASARPSILPSKDVKPKPIADAK----APE-----KRASPSKPASAPASRSG 535
                +    + + +   ++D  P  I   K    AP+     K  + ++  + P   + 
Sbjct: 813 KTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAK 872

Query: 536 SKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLS- 594
            K   T +K TT        P  + P T  PKKPT+ K       V+K      P  ++ 
Sbjct: 873 PKDRATNSKATT--------PKPQKP-TKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS 923

Query: 595 -----RPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPS 649
                 P S    +M +TTT     P + +V    K+         TP +  +P    P 
Sbjct: 924 TMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPE 983

Query: 650 ST 651
            T
Sbjct: 984 VT 985


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 91.7 bits (226), Expect = 3e-18
 Identities = 107/417 (25%), Positives = 156/417 (37%), Gaps = 66/417 (15%)

Query: 264 DLTLLSPKSENDKLKEISLACKITELESVSLPTPEIQSDFLHSKVEAPPSEVADTLVIMT 323
           D  + +P +   +  ++S + KIT  + ++ P P +           PP+  +DT     
Sbjct: 137 DFKVTTPDTSTTQHNKVSTSPKITTAKPIN-PRPSL-----------PPN--SDT----- 177

Query: 324 ASKGVRLPEPKDKILETPQKMTEKSESKTPGEGK-----------KEDKSRMAEPMKGYM 372
            SK   L   K+  +ET +  T   ++ T G+ K           K     +A   K   
Sbjct: 178 -SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA 236

Query: 373 RPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSP 432
           +PT     T   P  T  ++      K      P+E  P        I + P     P+P
Sbjct: 237 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT------IKSAPTTPKEPAP 290

Query: 433 EK-KTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRP 491
              K+ P    +PA T+T +    PT+ PK+PAPTT     K+P    +   P  P K P
Sbjct: 291 TTTKSAPTTPKEPAPTTTKEPA--PTT-PKEPAPTT----TKEPAPTTTKSAPTTP-KEP 342

Query: 492 AVASARPSILPSKDVKPKPIADAKAPEKRASPSKPAS-APASRSGSKSTQTVAKTTTAAA 550
           A  +      P K     P   A    K  +P+ P   AP ++  + +T      T    
Sbjct: 343 APTT------PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 396

Query: 551 VASTGPSSRSPSTLLPKKPTAIKTEGK--PAEVKKMTAKSVPADLSRPKSTSTSSMKKT- 607
            A T P   +P+T     PT  K      P E    T KS P     P  T+T S   T 
Sbjct: 397 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 456

Query: 608 -----TTLSGTAPAAGVVPS-RVKATPMPSRPS----TTPFIDKKPTSAKPSSTTPR 654
                TT    AP     P+      P P+ P     TTP      T+ KP+ TTP+
Sbjct: 457 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 513



 Score = 91.3 bits (225), Expect = 3e-18
 Identities = 109/370 (29%), Positives = 144/370 (38%), Gaps = 31/370 (8%)

Query: 306 SKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEKSESKTPGEGKKED-KSRM 364
           SKV A P+  A+T      +KG  L  PK+    TP++      S TP E      KS  
Sbjct: 232 SKVLAKPTPKAET-----TTKGPALTTPKEPTPTTPKEPA----STTPKEPTPTTIKSAP 282

Query: 365 AEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPP 424
             P +     TKS   TP  P  T  ++      K       +E  P    T +  TTP 
Sbjct: 283 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT--TKSAPTTP- 339

Query: 425 NKELPPSPEKKTKPLATTQPAKTS----TSKAKTQPTSLPKQPAPTT----IGGLNKKPM 476
            KE  P+  KK  P    +PA T+    T     +P    K+PAPTT         KKP 
Sbjct: 340 -KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 398

Query: 477 SLASGLVPAAPPKRPAVASAR-PSILPSKDVKPKPIADAKAPEKRASPSKPASAPAS-RS 534
                      PK PA  + + PS    K+  P     A    K  +P+   SAP + + 
Sbjct: 399 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 458

Query: 535 GSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKM--TAKSVPAD 592
            S +T      TT    A T P   +P+T     PT  K E  P   KK   T    PA 
Sbjct: 459 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP 517

Query: 593 LSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTT 652
            + PK T+ ++ KK T  +    A          TP    P TTP      T  +P+ TT
Sbjct: 518 TT-PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-TTPEEPTPTTPEEPAPTT 575

Query: 653 PRLSRLATNT 662
           P+ +  A NT
Sbjct: 576 PKAA--APNT 583



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 150/717 (20%), Positives = 233/717 (32%), Gaps = 73/717 (10%)

Query: 48  EKLPTPTPQVVKEGDSFPDTLAKNGQEIAPAQISKSLMVDNYTKDGVPGQERPKGPSAVV 107
           +K PTP P VV E  S  D    NG        + +   +  +        +P  P   +
Sbjct: 116 KKKPTPKPPVVDEAGSGLD----NGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSL 171

Query: 108 PSTSTGGVALPITTAIETVNIHGDHSLKNKAELADSMKNEAGIDEGHVIGESESVHSGAS 167
           P  S       +T   ET     + +  NK    D  +      E   I ++ +     +
Sbjct: 172 PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 231

Query: 168 KHSVEKVTELA----KGHLL-------PGVPVEDQSLPGEARALEGYADRGNFPAHPVNE 216
              + K T  A    KG  L       P  P E  S   +             P  P   
Sbjct: 232 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 291

Query: 217 EKETKEGSVAVQIPDLLEDKAQKLSFCEDQNAQDRNSKGSDSLNKKVDLTLLSPKSENDK 276
             ++   +     P   ++ A        + A     + + +  K    T   P     K
Sbjct: 292 TTKSAPTTPKEPAPTTTKEPAPTTP---KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 348

Query: 277 LKEISLACKITELESVSLPTPEIQSDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDK 336
            K      K     +   PTP    +   +  E  P+   +     TA K      PK+ 
Sbjct: 349 -KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP--TAPKKPAPTTPKEP 405

Query: 337 ILETPQK----MTEKSESKTPGE-GKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQE 391
              TP++     T++    TP E      KS      +     TKS   TP  P  T  +
Sbjct: 406 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 465

Query: 392 QERHKQLKSAGIARPEEGRPVVSGTGNDITTP----PNKELPPSPEKKTKPLATTQPAKT 447
           +      K      P++  P         TTP    P     P+P    +P  TT     
Sbjct: 466 EPAPTTPKEPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 524

Query: 448 STSKAKTQPT-------SLPKQPAPTTIGGLNKKPMSLASGLVPAAP------------P 488
            T+  K  PT       + P++PAPTT   L        +   P  P            P
Sbjct: 525 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 584

Query: 489 KRPAVASAR---------PSILPSKDVKP-KPIADAKAPEKRASPSKPASAPASRSGSKS 538
           K PA  + +         P+    K+  P  P   A    K  +P+ P   PA +  + +
Sbjct: 585 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP-KKPAPKELAPT 643

Query: 539 TQTVAKTTTAAAVASTGPSSRSPST------LLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
           T     +TT    A T P   +P+T        PK+P     +G      K  A + P  
Sbjct: 644 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 703

Query: 593 LSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTT 652
              PK  + ++ K  T+ +   PA          TP    P TTP   KKP    P +  
Sbjct: 704 -PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP-TTP---KKPAPTTPETPP 758

Query: 653 PRLSRLATNTSAPDLKNV-RSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSK 708
           P  S ++T T+  +   + +S   ST  +  +P    ++   K+  +    +   +K
Sbjct: 759 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK 815



 Score = 70.1 bits (170), Expect = 8e-12
 Identities = 95/376 (25%), Positives = 151/376 (40%), Gaps = 58/376 (15%)

Query: 323 TASKGVRLPEPKDKILETPQKMTEKSESKT-PGEGKKEDKSRMAEPMKGYMRPTKSRGLT 381
           T  KG     PK+    TP++    +   T P   K+   +   +P    + PT ++G  
Sbjct: 659 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG-- 716

Query: 382 PLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLAT 441
              P ST  ++      K      P+E  P          T P K  P +PE  T P  T
Sbjct: 717 ---PTSTTSDKPAPTTPKETAPTTPKEPAP----------TTPKKPAPTTPE--TPPPTT 761

Query: 442 TQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAA---PPKRPAVASARP 498
           ++ +  +T+K   +PT++ K P  +T          L++   P A    PK P V    P
Sbjct: 762 SEVSTPTTTK---EPTTIHKSPDEST--------PELSAEPTPKALENSPKEPGV----P 806

Query: 499 SILPSKDVKPKPIADAK-APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPS 557
           +       KP+    AK    +R   + P +  A+   +K T T  + TT + + +T   
Sbjct: 807 TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ 866

Query: 558 SRSPST--LLPKKPTAIKTEGKPAEV----KKMTAKSV---PADLSRPKSTSTSSMKKTT 608
             S +T    P K T +KT     +V    K +T   +   P + ++PK  +T+S  K T
Sbjct: 867 VTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNS--KAT 924

Query: 609 TLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDK---KPTSAKPSSTTPRLSRLATNTSAP 665
           T     P     P +  +T    +P T P + K    PT  K +ST P L+   T+  A 
Sbjct: 925 TPKPQKPTKA--PKKPTST---KKPKTMPRVRKPKTTPTPRKMTSTMPELN--PTSRIAE 977

Query: 666 DLKNVRSKVGSTENIK 681
            +    ++   T N K
Sbjct: 978 AMLQTTTRPNQTPNSK 993



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 88/395 (22%), Positives = 143/395 (36%), Gaps = 35/395 (8%)

Query: 295 PTPEIQSDFLHSKVEAP----PSEVADTLVIMTASKGVRLPEP---KDKILETPQKMTEK 347
           P P    +   +  E P    P E A T     A    + P P   K+    TP++    
Sbjct: 547 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 606

Query: 348 SESKT-PGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLL---PKSTIQEQERHKQLKSAGI 403
           +  +T P   K    + + EP     +    + L P     P ST  ++      K    
Sbjct: 607 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 666

Query: 404 ARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQP 463
             P+E  P         TTP  KE  P+  K T P    +PA T+  K        PK+ 
Sbjct: 667 TTPKEPAP---------TTP--KEPAPTTPKGTAPTTLKEPAPTTPKKPA------PKEL 709

Query: 464 APTTIGG----LNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEK 519
           APTT  G     + KP            PK PA  + +     + +  P   ++   P  
Sbjct: 710 APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTT 769

Query: 520 RASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPA 579
              P+    +P   +   S +   K    +      P++++P+   P+  T  K +    
Sbjct: 770 TKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 829

Query: 580 EVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVK-ATPMPSRPSTTPF 638
           ++ + T ++  A     K T+T++ +KTT    TA    V  +  +  TP       T  
Sbjct: 830 DL-RTTPETTTAAPKMTKETATTT-EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTT 887

Query: 639 IDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSK 673
           +  K T+ K + TT  +      T+ P  +   SK
Sbjct: 888 LAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSK 922



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 90/366 (24%), Positives = 131/366 (35%), Gaps = 45/366 (12%)

Query: 313 SEVADTLVIMTASKGVRLPEPKDKILETPQKMTEKSESK--TPGEGKKEDKSRMAEPMKG 370
           +EV D     T  K    P PK  +++      +  + K  TP     +       P   
Sbjct: 105 AEVKDNKKNRTKKK----PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKIT 160

Query: 371 YMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGND--ITTPPNKEL 428
             +P   R   P LP ++   +E    +        +E       T  D    T   KE 
Sbjct: 161 TAKPINPR---PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKET 217

Query: 429 PPSPEKKTKPLATT-----QPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLV 483
               +   K LA T     +P   + +  K    + PK+P PTT     K+P S      
Sbjct: 218 QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT----PKEPASTT---- 269

Query: 484 PAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVA 543
               PK P   + + +  P+   +P P     AP    +P +PA          + +  A
Sbjct: 270 ----PKEPTPTTIKSA--PTTPKEPAPTTTKSAP---TTPKEPAPTTTKEPAPTTPKEPA 320

Query: 544 KTTTAAAVASTGPSS----RSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKST 599
            TTT     +T  S+    + P+   PKKP A  T  +PA     T    P   +  +  
Sbjct: 321 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKP-APTTPKEPAP----TTPKEPTPTTPKEPA 375

Query: 600 STSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLA 659
            T+     TT    AP A   P+    TP    P TTP      T+ +PS TTP+     
Sbjct: 376 PTTKEPAPTTPKEPAPTAPKKPA--PTTPKEPAP-TTPKEPAPTTTKEPSPTTPKEPAPT 432

Query: 660 TNTSAP 665
           T  SAP
Sbjct: 433 TTKSAP 438



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 85/362 (23%), Positives = 126/362 (34%), Gaps = 42/362 (11%)

Query: 312  PSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEKSESK-TPGEGKKEDKSRMAEPMKG 370
            P   A T +   A    + P PK+    T +  T  +  K  P   K+   +   EP   
Sbjct: 685  PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP- 743

Query: 371  YMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIAR--PEEGRPVVSGTGNDITTPPNKEL 428
               P K    TP  P  T  E       K        P+E  P +S        P  K L
Sbjct: 744  -TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE------PTPKAL 796

Query: 429  PPSPEKK----TKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVP 484
              SP++     TK  A T+P  T+T+K KT    L   P  TT      K  +  +    
Sbjct: 797  ENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTT---E 853

Query: 485  AAPPKRPAVASARPSILPSKDVKPKPIADAK----APE-----KRASPSKPASAPASRSG 535
                 +    + + +   ++D  P  I   K    AP+     K  + ++  + P   + 
Sbjct: 854  KTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAK 913

Query: 536  SKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLS- 594
             K   T +K TT        P  + P T  PKKPT+ K       V+K      P  ++ 
Sbjct: 914  PKDRATNSKATT--------PKPQKP-TKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS 964

Query: 595  -----RPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPS 649
                  P S    +M +TTT     P + +V    K+         TP +  +P    P 
Sbjct: 965  TMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPE 1024

Query: 650  ST 651
             T
Sbjct: 1025 VT 1026


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 144/643 (22%), Positives = 235/643 (36%), Gaps = 109/643 (16%)

Query: 26    PRTPSELINKSSPLEVLESAACEKLPTPTPQVVKEGDSFPDTLAKNGQEIAPAQISKSLM 85
             P +  E+  +   +E +E  A    P   P+V+K+      T      E  PA++SK + 
Sbjct: 10245 PISEEEIPEEPPSIEEVEEVA----PPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIP 10300

Query: 86    VDNYTKDGVPGQERPKGPSAVVP----STSTGGVALPITTAIETVNIHGDHSLKNKAELA 141
              +   K  VP Q++ + P A VP          V +P   A+      G   L+ K  +A
Sbjct: 10301 EE---KVPVPVQKK-EAPPAKVPEVPKKVPEKKVLVPKKEAVPPAK--GRTVLEEKVSVA 10354

Query: 142   DSMKNEAGIDEGHVIGESESVHSGASKHSVEKVTELAKGHLLPGVPVEDQSLPGEARALE 201
                + E  + E   +   E+         VE++ E  + H      VE+    GE   +E
Sbjct: 10355 --FRQEVVVKERLELEVVEA--------EVEEIPEEEEFH-----EVEEYFEEGEFHEVE 10399

Query: 202   GYADRGNFPAHPVNEEKETKEGSVAVQIPDLLEDKAQKLSFCEDQNAQDRNSKGSDSL-- 259
              +        H V EE   ++    +++      +A+++   E   A  +  + S+ +  
Sbjct: 10400 EFI---KLEQHRVEEEHRVEKVHRVIEV-----FEAEEVEVFEKPKAPPKGPEISEKIIP 10451

Query: 260   NKKVDLTLLSPKSENDKLKEISLACKITELESVSLPTPEIQSDFLHSKVEAPPSEVADTL 319
              KK    ++  K    K+ E+    KI   E V +P           +   PP++V + L
Sbjct: 10452 PKKPPTKVVPRKEPPAKVPEVPK--KIVVEEKVRVP----------EEPRVPPTKVPEVL 10499

Query: 320   VIMTASKGVRLPEPKDKILETPQKMTEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRG 379
                      ++P P  K  E P     ++    P E   E K  +  P K  + PTK   
Sbjct: 10500 PPKEVVPEKKVPVPPAKKPEAPPPKVPEA----PKEVVPEKKVPVPPPKKPEVPPTK--- 10552

Query: 380   LTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPL 439
               P +PK+ + E    K++  A   +PE   P V     ++   P K++P +P KK +  
Sbjct: 10553 -VPEVPKAAVPE----KKVPEAIPPKPESPPPEVPEAPKEVV--PEKKVPAAPPKKPEVT 10605

Query: 440   ATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPS 499
                 P               PK+  P       KK        VP  PPK+P V   +  
Sbjct: 10606 PVKVP-------------EAPKEVVP------EKK--------VPVPPPKKPEVPPTKVP 10638

Query: 500   ILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSR 559
              +P   V  K + +A  P+  + P +    P         +   +   A  V    P++ 
Sbjct: 10639 EVPKVAVPEKKVPEAIPPKPESPPPEVFEEP--------EEVALEEPPAEVVEEPEPAAP 10690

Query: 560   SPSTLLPKKPTAIK----TEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAP 615
                T+ PKKP   K       K  E+  +    VP ++   K       KK        P
Sbjct: 10691 PQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVP 10750

Query: 616   AA--GVVPSRVKATPMPSR--PSTTPFIDKKPT-SAKPSSTTP 653
                  VVP +  A P      P+  P + KKP    KP+   P
Sbjct: 10751 EVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVP 10793



 Score = 66.6 bits (161), Expect = 9e-11
 Identities = 85/366 (23%), Positives = 129/366 (35%), Gaps = 42/366 (11%)

Query: 285   KITELESVSLPTPEIQSDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQKM 344
             K+ E+   ++P  ++  + +  K E+PP EV +    +   K V    PK K   TP K+
Sbjct: 10552 KVPEVPKAAVPEKKVP-EAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPK-KPEVTPVKV 10609

Query: 345   TEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIA 404
              E  +   P     E K  +  P K  + PTK     P +PK  + E    K++  A   
Sbjct: 10610 PEAPKEVVP-----EKKVPVPPPKKPEVPPTK----VPEVPKVAVPE----KKVPEAIPP 10656

Query: 405   RPEEGRPVVSGTGNDITTP-PNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQP 463
             +PE   P V     ++    P  E+   PE    P  T  P K    K      +   + 
Sbjct: 10657 KPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPEL 10716

Query: 464   APTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPE----- 518
              P  +  + K+ +      VP   PK+P    A+   +P + V  K +A  K PE     
Sbjct: 10717 PPVKVPEVPKEVVPEKK--VPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAK 10774

Query: 519   ------KRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAI 572
                   K     KPA     R+ S   +   +    A      P    P  +  ++   +
Sbjct: 10775 VPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEV 10834

Query: 573   KTEGKPAEVKK-MTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPS 631
                  P E KK +  K VP             +KK        P    V  + K  P P 
Sbjct: 10835 PPPAVPEEPKKIIPEKKVPV------------IKKPEAPPPKEPEPEKVIEKPKLKPRPP 10882

Query: 632   RPSTTP 637
              P   P
Sbjct: 10883 PPPPAP 10888



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 78/342 (22%), Positives = 127/342 (37%), Gaps = 54/342 (15%)

Query: 286   ITELESVSLPTPEIQSDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQKMT 345
             ITE E   +P   +  + + +K +APP++V    V            P++K+     K  
Sbjct: 9786  ITEPEK-PIPVKPVPEEPVPTKPKAPPAKVLKKAV------------PEEKVPVPIPKKL 9832

Query: 346   EKSESKTPGEGKK--EDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQ----------- 392
             +    K P E KK  E+K R++   +   + T+     P+ PK  + E+           
Sbjct: 9833  KPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAP 9892

Query: 393   -----ERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTK-------PLA 440
                  E  K+L+   +A  EE   VV+     +     + +    E  T+       P+ 
Sbjct: 9893  PVRVPEVPKELEPEEVAFEEE---VVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVK 9949

Query: 441   TTQ-PAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPS 499
               + P K    + K  P    K+  P  +  + KKP       VP   PK+     A+  
Sbjct: 9950  VPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKP----EEKVPVLIPKKEKPPPAKVP 10005

Query: 500   ILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSR 559
              +P K V  + +      +  A P+K    P      K     A     A  A       
Sbjct: 10006 EVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKV---PE 10062

Query: 560   SPSTLLP--KKPTAI--KTEGKPAEVKKMTAKSVPADLSRPK 597
              P  L+P  KKPT +  K E  P +V K   + VP  ++ P+
Sbjct: 10063 VPKKLIPEEKKPTPVPKKVEAPPPKVPK-KREPVPVPVALPQ 10103



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 84/395 (21%), Positives = 136/395 (34%), Gaps = 58/395 (14%)

Query: 290  ESVSLPTPEIQSDFLH--------SKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETP 341
            E VS+  PE+Q + +         SK   PP +V +        +   +P PK K+    
Sbjct: 9255 EEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPK-KVEPPA 9313

Query: 342  QKMTEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSA 401
             K+ E  +   P     E+K  +  P K    P K     P +PK  + E++        
Sbjct: 9314 PKVPEVPKKPVP-----EEKKPVPVPKKEPAAPPK----VPEVPKKPVPEEKI-----PV 9359

Query: 402  GIARPEEGRPV-VSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLP 460
             +A+ +E  P  V      + T     +    E+   P     P K    + K  P    
Sbjct: 9360 PVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEE 9419

Query: 461  KQPAPTTIGGLNKKPMSLASGLVPA-----APPKRPAVASARPSILPSKDVKPKPIADAK 515
            + P P  +  L KKP+      VP      APP R  V  ++ +++  K    +      
Sbjct: 9420 EVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEV--SKKTVVEEKRFVAEEKLSFA 9477

Query: 516  APEKRASPSKPASAPASRSGSKSTQTVA--------KTTTAAAVASTGPSSRSPSTLLPK 567
             P++        SA    S S+  + V+        +     A  +       P   + +
Sbjct: 9478 VPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVE 9537

Query: 568  KPTAI---KTEGKPAEV-----KKMTAK-SVPADLSRPKSTSTSSMKKTTTLSGTAPAAG 618
            +   I   + E +PAEV     KK+  K  +PA +  P         K        PA  
Sbjct: 9538 EKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAP- 9596

Query: 619  VVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTP 653
             VP + K  P        P + ++P    P    P
Sbjct: 9597 -VPKKEKVPP--------PKVPEEPKKPVPEKKVP 9622



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 139/691 (20%), Positives = 246/691 (35%), Gaps = 128/691 (18%)

Query: 41  VLESAACEKLPTPTPQVV----KEGDSFPDTLAKNGQ---EIAPAQISKSLMVDNYTKDG 93
           V++ AA ++LP  TP  +    K     P ++A   Q   + +P+ I  S     + +  
Sbjct: 240 VIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAP 299

Query: 94  VPGQERPKGPSAVVPSTSTGGVALPITTAIETVNIHGDHSLKNKAELADSMKNEAGIDEG 153
            P   R   P+A + ++    V  P+       +     ++    E+    K E     G
Sbjct: 300 TPSPVRSVSPAARISTSPIRSVRSPLLMRKTQAS-----TVATGPEVPPPWKQE-----G 349

Query: 154 HVIGESESVHSGASKHSVEKVTELAKGHLLPGVPVEDQSLPGEARALEGYADRGNFPAHP 213
           +V   SE+     +  +  ++    +     GV  E  ++ G A A    +   ++ A  
Sbjct: 350 YVASSSEAEMRETTLTTSTQIRTEERWEGRYGVQ-EQVTISGAAGAAASVSASASYAAEA 408

Query: 214 V----NEEKETKEGSVAVQIPDLLEDKA---QKLSFCEDQNAQDRNSKG------SDSLN 260
           V     E K+  + S AV       D A   + +    +Q AQ   +         + + 
Sbjct: 409 VATGAKEVKQDADKSAAVATVVAAVDMARVREPVISAVEQTAQRTTTTAVHIQPAQEQVR 468

Query: 261 KKVDLTLLSPKS-ENDKLKEISLACKITELESVSLPTPEIQSDFLHSKVEAPPSEVADTL 319
           K+ + T ++      DK KE  L  +  E+    + T + Q    H ++     +     
Sbjct: 469 KEAEKTAVTKVVVAADKAKEQELKSRTKEV----ITTKQEQMHVTHEQIRKETEKTFVPK 524

Query: 320 VIMTASKGVRLPEPKDKILETPQKMTEKSESKTPGEGKKED-------------KSRMAE 366
           V+++A+K       K++     +++T+K +  T    ++E              KS   E
Sbjct: 525 VVISAAKA------KEQETRISEEITKKQKQVTQEAIRQETEITAASMVVVATAKSTKLE 578

Query: 367 PMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNK 426
            + G    T ++     L    I ++ R   +    +A P+     +   G +  T   +
Sbjct: 579 TVPGAQEETTTQQDQMHLSYEKIMKETRKTVVPKVIVATPKVKEQDLVSRGREGITTKRE 638

Query: 427 ELPPSPEKKTKPLATT--QPAKTSTSKAKTQPTSL------------------------- 459
           ++  + EK  K    T       +T+KAK Q T L                         
Sbjct: 639 QVQITQEKMRKEAEKTALSTIAVATAKAKEQETILRTRETMATRQEQIQVTHGKVDVGKK 698

Query: 460 ------------------PKQPA--------PTTIGGLNKKPMSLASGLVPAAPPKRPAV 493
                             P++P          TT+    K+ +S A     A PP+RPA 
Sbjct: 699 AEAVATVVAAVDQARVREPREPGHLEESYAQQTTLEYGYKERISAAK---VAEPPQRPA- 754

Query: 494 ASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAS 553
             + P ++P K VKP+ I   +AP +  +  K          S+  +T   TT       
Sbjct: 755 --SEPHVVP-KAVKPRVI---QAPSE--THIKTTDQKGMHISSQIKKTTDLTTERLVHVD 806

Query: 554 TGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGT 613
             P + SP   + K        G  A +    A S  A L +  S ++S+ K T ++   
Sbjct: 807 KRPRTASPHFTVSKISVPKTEHGYEASI----AGSAIATLQKELSATSSAQKITKSVK-- 860

Query: 614 APAAGVVPSRVKATPMPSRPSTTPFIDKKPT 644
           AP      +RV+A P P      PF D   T
Sbjct: 861 APTVKPSETRVRAEPTPL--PQFPFADTPDT 889



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 124/624 (19%), Positives = 214/624 (34%), Gaps = 134/624 (21%)

Query: 26    PRTPSELINKSSPLEVLESAACE-KLPTPTPQVVKEGDSFPDTLAKNGQEIAPAQISKSL 84
             P  P     K+ P +VL+ A  E K+P P P+ +K     P  + +  +++   +I  S+
Sbjct: 9799  PEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPP---PPKVPEEPKKVFEEKIRISI 9855

Query: 85    MVDNYTKDGVPGQERPKGPSAVVPSTSTGGVALPITTAIETVNIHGDHSLKNKAELADSM 144
                   +   P  + P  P  VV       V +P       V +          E+A   
Sbjct: 9856  TKREKEQVTEPAAKVPMKPKRVVAEEK---VPVPRKEVAPPVRVPEVPKELEPEEVAFEE 9912

Query: 145   KNEAGIDEGHVIGESESVHSGASKHSVEKVTELAKGHLLPGVPVEDQSLPGEARALEGYA 204
             +    ++E  V  E E +H        E+   + +  ++P +PV+   +P +        
Sbjct: 9913  EVVTHVEEYLVEEEEEYIH--------EEEEFITEEEVVPVIPVKVPEVPRK-------- 9956

Query: 205   DRGNFPAHPVNEEKET-----KEGSVAVQIPDLLEDKAQKLSFCEDQNAQDRNSKGSDSL 259
                     PV EEK+      K+ +   ++P++ +   +K+                   
Sbjct: 9957  --------PVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVP------------------ 9990

Query: 260   NKKVDLTLLSPKSENDKLKEI-SLACKITELESVSLPTPEIQSDFLHSKVEAPPSEVADT 318
                    +L PK E     ++  +  K    E V +P P+        KVEAPP++V + 
Sbjct: 9991  -------VLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPK--------KVEAPPAKVPEV 10035

Query: 319   LVIMTASKGVRLPEPKD------KILETPQKMTEKSESKTPGEGKKE------DKSRMAE 366
                    K V +P PK       K+ E P+K+  + +  TP   K E       K R   
Sbjct: 10036 PKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPV 10095

Query: 367   PMKGYMRPTKSRGL--TPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPP 424
             P+   + P +   L    ++P+  +  +E  + L       PEE   +      +   P 
Sbjct: 10096 PVPVAL-PQEEEVLFEEEIVPEEEVLPEEE-EVLPEEEEVLPEEEEVLPE---EEEIPPE 10150

Query: 425   NKELPPS-----------PEKKTKP-----LATTQPAKTSTSKAKTQPTSLPK--QPAPT 466
              +E+PP            PE++  P     +    P      K   +   +PK  +  P 
Sbjct: 10151 EEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPA 10210

Query: 467   TIGGLNKK---------------PMS---------LASGLVPAAPPKRPAVASARPSILP 502
              +  + KK               P+          ++   +P  PP    V    P  +P
Sbjct: 10211 KVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVP 10270

Query: 503   SKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSS-RSP 561
                 K  P A    P+K  +P  PA         K    V K     A     P      
Sbjct: 10271 EVIKKAVPEAPTPVPKKVEAP--PAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEK 10328

Query: 562   STLLPKKPTAIKTEGKPAEVKKMT 585
               L+PKK      +G+    +K++
Sbjct: 10329 KVLVPKKEAVPPAKGRTVLEEKVS 10352



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 54/209 (25%), Positives = 82/209 (39%), Gaps = 28/209 (13%)

Query: 333   PKDKILETPQ--KMTEKSESKTPGEGKKEDK---SRMAEP-----MKGYMRPTKSRGLTP 382
             PK K+ E PQ  +  E +  K PG  KK  K    R  EP     +K  +R         
Sbjct: 10904 PKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPK 10963

Query: 383   LLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELP--------PSPEK 434
             + PK    E+ +   +      +P E   V + T  +   P   ++P        P+PE 
Sbjct: 10964 VEPKKL--EKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEP 11021

Query: 435   KTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRP--A 492
             K KP A  +  K    + +  P +     AP T+  + KK  + A     AA PK P   
Sbjct: 11022 KPKPEAEVKTIKPPPVEPEPTPIA-----APVTVPVVGKKAEAKAP-KEEAAKPKGPIKG 11075

Query: 493   VASARPSILPSKDVKPKPIADAKAPEKRA 521
             V    PS + ++  K +P +  + P   A
Sbjct: 11076 VPKKTPSPIEAERRKLRPGSGGEKPPDEA 11104



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 11/90 (12%)

Query: 406  PEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAP 465
            PEE  PVV+        PP   L P+PE+K  P    +  K +  K   +  + PK+  P
Sbjct: 8954 PEEIPPVVA--------PPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTP 9005

Query: 466  TTIGGLNKKPMSLASGLVPAAPPKRPAVAS 495
                 + KKP    + L+PA  P+   V+S
Sbjct: 9006 RE--EIVKKPPP-PTTLIPAKAPEIIDVSS 9032



 Score = 30.8 bits (68), Expect = 5.3
 Identities = 32/141 (22%), Positives = 52/141 (36%), Gaps = 6/141 (4%)

Query: 385  PKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEK-KTKPLATTQ 443
            P    + QE+   LK    A+ EE  P           P  K   P P+K K  P    +
Sbjct: 9551 PAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPE 9610

Query: 444  PAKTSTSKAKTQPTSLP-KQPAPTTIG----GLNKKPMSLASGLVPAAPPKRPAVASARP 498
              K    + K  P  +  ++P P  +      + ++   L +     APPK       + 
Sbjct: 9611 EPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKR 9670

Query: 499  SILPSKDVKPKPIADAKAPEK 519
            ++   K +K KP  + + P K
Sbjct: 9671 AVPEEKVLKLKPKREEEPPAK 9691


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 66/259 (25%), Positives = 92/259 (35%), Gaps = 20/259 (7%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTI----GGLNKKPMS 477
            +PP     P P   T    TT P+  +T+     PT+ P  P  TT           P+S
Sbjct: 1400 SPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIS 1459

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK 537
              +   P   P  P    + P+  PS      P      P    +PS P + P +   S 
Sbjct: 1460 TTTTPPPTTTPSPPTTTPSPPTTTPS-----PPTTTTTTPPPTTTPSPPTTTPITPPAST 1514

Query: 538  STQTVAKTTTAAAVASTGP---SSRSPSTLLPKKP----TAIKTEGKPAEVKKMTAKSVP 590
            +T     T +     +T P   ++ SP T  P  P    T +     P+     T    P
Sbjct: 1515 TTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1574

Query: 591  ADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATP----MPSRPSTTPFIDKKPTSA 646
                 P +T+T S    TT +         P+    TP     PS P+TTP      T+ 
Sbjct: 1575 TTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTT 1634

Query: 647  KPSSTTPRLSRLATNTSAP 665
             P +TTP      T T  P
Sbjct: 1635 LPPTTTPSPPPTTTTTPPP 1653



 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 68/260 (26%), Positives = 94/260 (36%), Gaps = 20/260 (7%)

Query: 421  TTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLAS 480
            TTPP    P  P   T    TT P  T+ S   T P+     P+P T       P +   
Sbjct: 1446 TTPPPTTTPSPPISTT----TTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTT--- 1498

Query: 481  GLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQ 540
               P+ P   P    A  + LP       P      P    +PS P + P +     ST 
Sbjct: 1499 --TPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP--TSTT 1554

Query: 541  TVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTS 600
            T+  TTT +   +T  ++  P T  P  PT       P+     T    P     P +T+
Sbjct: 1555 TLPPTTTPSPPPTT--TTTPPPTTTPSPPTTTT----PSPPTITTTTPPPTTTPSPPTTT 1608

Query: 601  TSSMKKTTTLSGTAPAAGVVPSRVKATP---MPSRPSTTPFIDKKPTSAKPSSTTPRLSR 657
            T++   TTT S         P+     P    PS P TT       T+  P +TT     
Sbjct: 1609 TTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP 1668

Query: 658  LATNTSAPDLKNVRSKVGST 677
            + T T+ P      S + +T
Sbjct: 1669 ITTTTTPPPTTTPSSPITTT 1688



 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 77/288 (26%), Positives = 99/288 (34%), Gaps = 31/288 (10%)

Query: 406  PEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATT-QPAKTSTSKAKTQPTSLP---K 461
            P    P+   T      P     PP     T P  TT  P  T+T    T  T+ P    
Sbjct: 1541 PPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTT 1600

Query: 462  QPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRA 521
             P+P T       P +      P+ P   P       + LP       P      P    
Sbjct: 1601 TPSPPTTTTTTPPPTT-----TPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTT 1655

Query: 522  SPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEV 581
            +PS P +         +T +   TTT     +T PS  SP T  P  PT   T   P   
Sbjct: 1656 TPSPPTT---------TTPSPPITTTTTPPPTTTPS--SPITTTPSPPTTTMTTPSPT-- 1702

Query: 582  KKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDK 641
               T  S     + P ST+T S   TT    T P+    PS    T M + P TT     
Sbjct: 1703 --TTPSSPITTTTTPSSTTTPSPPPTTM---TTPSPTTTPS-PPTTTMTTLPPTTTSSPL 1756

Query: 642  KPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIK---HQPGG 686
              T   PS T P  S  +T T       + +  G  ++ K   H+PGG
Sbjct: 1757 TTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGG 1804



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 52/188 (27%), Positives = 67/188 (35%), Gaps = 18/188 (9%)

Query: 484  PAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP----ASAPASRSGSK-- 537
            P+ P   P+      + LP       P      P    +PS P     + P + + S   
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPI 1458

Query: 538  STQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPK 597
            ST T    TT  +  +T P   SP T  P  PT   T   P      T  S P       
Sbjct: 1459 STTTTPPPTTTPSPPTTTP---SPPTTTPSPPTTTTTTPPPT-----TTPSPPTTTPITP 1510

Query: 598  STSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSR 657
              ST+++  TTT S         P     T  PS P+TTP      T+  P +TTP    
Sbjct: 1511 PASTTTLPPTTTPSPPTTTTTTPP----PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1566

Query: 658  LATNTSAP 665
              T T  P
Sbjct: 1567 TTTTTPPP 1574



 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 56/248 (22%), Positives = 87/248 (35%), Gaps = 26/248 (10%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 4005 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4064

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK 537
              + + P   P      +  P I  +  V P P               P + P + +   
Sbjct: 4065 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTPTTTPITTT--- 4112

Query: 538  STQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPK 597
            +T T   T T     +T P + + +      PT  +T          T    P     P 
Sbjct: 4113 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PT 4168

Query: 598  STSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSR 657
             T T +    TT +   P     P+  +  P P+  ST P  +   ++  P S+TP+ SR
Sbjct: 4169 GTQTPTTTPITTTTTVTPTP--TPTGTQTGP-PTHTSTAPIAELTTSNPPPESSTPQTSR 4225

Query: 658  LATNTSAP 665
               +TS+P
Sbjct: 4226 ---STSSP 4230



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 1912 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 1971

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 1972 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2028

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2029 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2085

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2086 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2139

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2140 TPTPTGTQTPTTTPITTTTT 2159



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 1935 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 1994

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 1995 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2051

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2052 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2108

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2109 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2162

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2163 TPTPTGTQTPTTTPITTTTT 2182



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 1958 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2017

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2018 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2074

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2075 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2131

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2132 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2185

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2186 TPTPTGTQTPTTTPITTTTT 2205



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 1981 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2040

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2041 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2097

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2098 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2154

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2155 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2208

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2209 TPTPTGTQTPTTTPITTTTT 2228



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2004 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2063

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2064 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2120

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2121 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2177

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2178 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2231

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2232 TPTPTGTQTPTTTPITTTTT 2251



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2027 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2086

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2087 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2143

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2144 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2200

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2201 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2254

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2255 TPTPTGTQTPTTTPITTTTT 2274



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2050 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2109

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2110 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2166

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2167 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2223

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2224 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2277

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2278 TPTPTGTQTPTTTPITTTTT 2297



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2073 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2132

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2133 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2189

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2190 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2246

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2247 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2300

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2301 TPTPTGTQTPTTTPITTTTT 2320



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2096 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2155

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2156 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2212

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2213 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2269

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2270 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2323

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2324 TPTPTGTQTPTTTPITTTTT 2343



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2119 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2178

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2179 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2235

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2236 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2292

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2293 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2346

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2347 TPTPTGTQTPTTTPITTTTT 2366



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2142 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2201

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2202 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2258

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2259 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2315

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2316 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2369

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2370 TPTPTGTQTPTTTPITTTTT 2389



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2165 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2224

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2225 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2281

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2282 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2338

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2339 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2392

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2393 TPTPTGTQTPTTTPITTTTT 2412



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2188 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2247

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2248 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2304

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2305 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2361

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2362 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2415

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2416 TPTPTGTQTPTTTPITTTTT 2435



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2211 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2270

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2271 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2327

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2328 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2384

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2385 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2438

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2439 TPTPTGTQTPTTTPITTTTT 2458



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2234 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2293

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2294 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2350

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2351 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2407

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2408 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2461

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2462 TPTPTGTQTPTTTPITTTTT 2481



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2257 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2316

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2317 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2373

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2374 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2430

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2431 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2484

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2485 TPTPTGTQTPTTTPITTTTT 2504



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2280 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2339

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2340 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2396

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2397 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2453

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2454 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2507

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2508 TPTPTGTQTPTTTPITTTTT 2527



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2303 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2362

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2363 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2419

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2420 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2476

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2477 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2530

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2531 TPTPTGTQTPTTTPITTTTT 2550



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2326 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2385

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2386 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2442

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2443 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2499

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2500 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2553

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2554 TPTPTGTQTPTTTPITTTTT 2573



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2349 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2408

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2409 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2465

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2466 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2522

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2523 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2576

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2577 TPTPTGTQTPTTTPITTTTT 2596



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2372 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2431

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2432 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2488

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2489 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2545

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2546 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2599

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2600 TPTPTGTQTPTTTPITTTTT 2619



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2395 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2454

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2455 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2511

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2512 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2568

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2569 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2622

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2623 TPTPTGTQTPTTTPITTTTT 2642



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2418 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2477

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2478 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2534

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2535 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2591

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2592 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2645

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2646 TPTPTGTQTPTTTPITTTTT 2665



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2441 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2500

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2501 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2557

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2558 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2614

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2615 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2668

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2669 TPTPTGTQTPTTTPITTTTT 2688



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2464 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2523

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2524 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2580

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2581 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2637

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2638 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2691

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2692 TPTPTGTQTPTTTPITTTTT 2711



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2487 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2546

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2547 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2603

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2604 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2660

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2661 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2714

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2715 TPTPTGTQTPTTTPITTTTT 2734



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2510 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2569

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2570 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2626

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2627 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2683

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2684 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2737

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2738 TPTPTGTQTPTTTPITTTTT 2757



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2533 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2592

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2593 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2649

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2650 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2706

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2707 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2760

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2761 TPTPTGTQTPTTTPITTTTT 2780



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2556 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2615

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2616 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2672

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2673 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2729

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2730 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2783

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2784 TPTPTGTQTPTTTPITTTTT 2803



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2579 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2638

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2639 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2695

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2696 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2752

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2753 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2806

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2807 TPTPTGTQTPTTTPITTTTT 2826



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2602 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2661

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2662 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2718

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2719 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2775

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2776 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2829

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2830 TPTPTGTQTPTTTPITTTTT 2849



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2625 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2684

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2685 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2741

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2742 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2798

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2799 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2852

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2853 TPTPTGTQTPTTTPITTTTT 2872



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2648 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2707

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2708 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2764

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2765 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2821

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2822 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2875

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2876 TPTPTGTQTPTTTPITTTTT 2895



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2671 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2730

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2731 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2787

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2788 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2844

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2845 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2898

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2899 TPTPTGTQTPTTTPITTTTT 2918



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2694 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2753

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2754 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2810

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2811 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2867

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2868 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2921

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2922 TPTPTGTQTPTTTPITTTTT 2941



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2717 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2776

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2777 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2833

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2834 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2890

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2891 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2944

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2945 TPTPTGTQTPTTTPITTTTT 2964



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2740 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2799

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2800 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2856

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2857 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2913

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2914 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2967

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2968 TPTPTGTQTPTTTPITTTTT 2987



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2763 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2822

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2823 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2879

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2880 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2936

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2937 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2990

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 2991 TPTPTGTQTPTTTPITTTTT 3010



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2786 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2845

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2846 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2902

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2903 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2959

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2960 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3013

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3014 TPTPTGTQTPTTTPITTTTT 3033



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2809 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2868

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2869 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2925

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2926 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 2982

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 2983 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3036

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3037 TPTPTGTQTPTTTPITTTTT 3056



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2832 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2891

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2892 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2948

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2949 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3005

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3006 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3059

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3060 TPTPTGTQTPTTTPITTTTT 3079



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2855 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2914

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2915 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2971

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2972 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3028

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3029 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3082

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3083 TPTPTGTQTPTTTPITTTTT 3102



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2878 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2937

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2938 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 2994

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 2995 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3051

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3052 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3105

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3106 TPTPTGTQTPTTTPITTTTT 3125



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2901 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2960

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2961 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3017

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3018 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3074

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3075 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3128

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3129 TPTPTGTQTPTTTPITTTTT 3148



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2924 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2983

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 2984 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3040

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3041 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3097

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3098 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3151

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3152 TPTPTGTQTPTTTPITTTTT 3171



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2947 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3006

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3007 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3063

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3064 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3120

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3121 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3174

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3175 TPTPTGTQTPTTTPITTTTT 3194



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2970 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3029

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3030 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3086

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3087 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3143

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3144 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3197

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3198 TPTPTGTQTPTTTPITTTTT 3217



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 2993 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3052

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3053 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3109

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3110 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3166

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3167 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3220

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3221 TPTPTGTQTPTTTPITTTTT 3240



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3016 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3075

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3076 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3132

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3133 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3189

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3190 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3243

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3244 TPTPTGTQTPTTTPITTTTT 3263



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3039 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3098

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3099 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3155

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3156 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3212

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3213 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3266

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3267 TPTPTGTQTPTTTPITTTTT 3286



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3062 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3121

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3122 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3178

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3179 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3235

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3236 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3289

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3290 TPTPTGTQTPTTTPITTTTT 3309



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3085 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3144

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3145 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3201

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3202 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3258

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3259 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3312

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3313 TPTPTGTQTPTTTPITTTTT 3332



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3108 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3167

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3168 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3224

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3225 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3281

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3282 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3335

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3336 TPTPTGTQTPTTTPITTTTT 3355



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3131 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3190

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3191 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3247

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3248 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3304

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3305 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3358

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3359 TPTPTGTQTPTTTPITTTTT 3378



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3154 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3213

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3214 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3270

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3271 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3327

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3328 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3381

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3382 TPTPTGTQTPTTTPITTTTT 3401



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3177 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3236

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3237 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3293

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3294 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3350

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3351 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3404

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3405 TPTPTGTQTPTTTPITTTTT 3424



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3200 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3259

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3260 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3316

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3317 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3373

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3374 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3427

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3428 TPTPTGTQTPTTTPITTTTT 3447



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3223 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3282

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3283 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3339

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3340 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3396

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3397 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3450

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3451 TPTPTGTQTPTTTPITTTTT 3470



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3246 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3305

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3306 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3362

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3363 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3419

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3420 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3473

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3474 TPTPTGTQTPTTTPITTTTT 3493



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3269 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3328

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3329 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3385

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3386 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3442

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3443 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3496

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3497 TPTPTGTQTPTTTPITTTTT 3516



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3292 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3351

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3352 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3408

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3409 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3465

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3466 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3519

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3520 TPTPTGTQTPTTTPITTTTT 3539



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3315 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3374

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3375 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3431

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3432 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3488

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3489 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3542

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3543 TPTPTGTQTPTTTPITTTTT 3562



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3338 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3397

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3398 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3454

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3455 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3511

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3512 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3565

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3566 TPTPTGTQTPTTTPITTTTT 3585



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3361 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3420

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3421 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3477

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3478 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3534

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3535 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3588

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3589 TPTPTGTQTPTTTPITTTTT 3608



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3384 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3443

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3444 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3500

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3501 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3557

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3558 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3611

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3612 TPTPTGTQTPTTTPITTTTT 3631



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3407 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3466

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3467 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3523

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3524 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3580

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3581 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3634

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3635 TPTPTGTQTPTTTPITTTTT 3654



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3430 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3489

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3490 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3546

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3547 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3603

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3604 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3657

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3658 TPTPTGTQTPTTTPITTTTT 3677



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3453 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3512

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3513 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3569

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3570 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3626

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3627 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3680

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3681 TPTPTGTQTPTTTPITTTTT 3700



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3476 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3535

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3536 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3592

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3593 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3649

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3650 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3703

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3704 TPTPTGTQTPTTTPITTTTT 3723



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3499 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3558

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3559 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3615

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3616 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3672

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3673 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3726

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3727 TPTPTGTQTPTTTPITTTTT 3746



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3522 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3581

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3582 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3638

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3639 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3695

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3696 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3749

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3750 TPTPTGTQTPTTTPITTTTT 3769



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3545 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3604

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3605 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3661

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3662 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3718

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3719 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3772

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3773 TPTPTGTQTPTTTPITTTTT 3792



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3568 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3627

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3628 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3684

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3685 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3741

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3742 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3795

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3796 TPTPTGTQTPTTTPITTTTT 3815



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3591 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3650

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3651 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3707

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3708 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3764

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3765 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3818

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3819 TPTPTGTQTPTTTPITTTTT 3838



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3614 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3673

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3674 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3730

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3731 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3787

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3788 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3841

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3842 TPTPTGTQTPTTTPITTTTT 3861



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3637 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3696

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3697 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3753

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3754 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3810

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3811 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3864

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3865 TPTPTGTQTPTTTPITTTTT 3884



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3660 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3719

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3720 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3776

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3777 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3833

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3834 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3887

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3888 TPTPTGTQTPTTTPITTTTT 3907



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3683 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3742

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3743 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3799

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3800 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3856

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3857 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3910

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3911 TPTPTGTQTPTTTPITTTTT 3930



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3706 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3765

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3766 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3822

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3823 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3879

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3880 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3933

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3934 TPTPTGTQTPTTTPITTTTT 3953



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3729 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3788

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3789 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3845

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3846 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3902

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3903 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3956

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3957 TPTPTGTQTPTTTPITTTTT 3976



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3752 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3811

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3812 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3868

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3869 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3925

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3926 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3979

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 3980 TPTPTGTQTPTTTPITTTTT 3999



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3775 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3834

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3835 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3891

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3892 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3948

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3949 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4002

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 4003 TPTPTGTQTPTTTPITTTTT 4022



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3798 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3857

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3858 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3914

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3915 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3971

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3972 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4025

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 4026 TPTPTGTQTPTTTPITTTTT 4045



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 58/260 (22%), Positives = 90/260 (34%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3821 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3880

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPAS 532
              + + P   P      +  P I  +  V P P           P    +   P   P  
Sbjct: 3881 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-- 3937

Query: 533  RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPAD 592
             +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P  
Sbjct: 3938 -TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI- 3994

Query: 593  LSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
                  T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 3995 ------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4048

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 4049 TPTPTGTQTPTTTPITTTTT 4068



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 61/270 (22%), Positives = 92/270 (34%), Gaps = 30/270 (11%)

Query: 412  VVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTT 467
            V   T    TT  N   P +    T    T  P  T T    T P    T++   P PT 
Sbjct: 1879 VTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 1938

Query: 468  IGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRAS 522
                   P++  + + P   P      +  P I  +  V P P           P    +
Sbjct: 1939 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTT 1997

Query: 523  PSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVK 582
               P   P   +G+++  T   TTT     +  P+     T  P   T   T   P    
Sbjct: 1998 TVTPTPTP---TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTG 2053

Query: 583  KMTAKSVPADLSRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTT 636
              T  + P        T+T+++  T T +GT  P    + +    TP P+      P+TT
Sbjct: 2054 TQTPTTTPI-------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2106

Query: 637  PFIDKKPTSAKPSST---TPRLSRLATNTS 663
            P       +  P+ T   TP  + + T T+
Sbjct: 2107 PITTTTTVTPTPTPTGTQTPTTTPITTTTT 2136



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 56/260 (21%), Positives = 91/260 (35%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3844 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3903

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK 537
              + + P   P      +  P I  +  V P P               P + P + +   
Sbjct: 3904 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTPTTTPITTT--- 3951

Query: 538  STQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKMTAKSVPADLSR 595
            +T T   T T     +T P + + +      PT  +T           +T    P     
Sbjct: 3952 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4011

Query: 596  PKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
            P +   T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 4012 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4071

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 4072 TPTPTGTQTPTTTPITTTTT 4091



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 56/260 (21%), Positives = 91/260 (35%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3867 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3926

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK 537
              + + P   P      +  P I  +  V P P               P + P + +   
Sbjct: 3927 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTPTTTPITTT--- 3974

Query: 538  STQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKMTAKSVPADLSR 595
            +T T   T T     +T P + + +      PT  +T           +T    P     
Sbjct: 3975 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4034

Query: 596  PKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
            P +   T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 4035 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4094

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 4095 TPTPTGTQTPTTTPITTTTT 4114



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 56/260 (21%), Positives = 91/260 (35%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3890 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3949

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK 537
              + + P   P      +  P I  +  V P P               P + P + +   
Sbjct: 3950 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTPTTTPITTT--- 3997

Query: 538  STQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKMTAKSVPADLSR 595
            +T T   T T     +T P + + +      PT  +T           +T    P     
Sbjct: 3998 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4057

Query: 596  PKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
            P +   T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 4058 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4117

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 4118 TPTPTGTQTPTTTPITTTTT 4137



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 56/260 (21%), Positives = 91/260 (35%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3913 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3972

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK 537
              + + P   P      +  P I  +  V P P               P + P + +   
Sbjct: 3973 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTPTTTPITTT--- 4020

Query: 538  STQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKMTAKSVPADLSR 595
            +T T   T T     +T P + + +      PT  +T           +T    P     
Sbjct: 4021 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4080

Query: 596  PKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
            P +   T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 4081 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4140

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 4141 TPTPTGTQTPTTTPITTTTT 4160



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 56/260 (21%), Positives = 91/260 (35%), Gaps = 30/260 (11%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 3936 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3995

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK 537
              + + P   P      +  P I  +  V P P               P + P + +   
Sbjct: 3996 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTP--------TGTQTPTTTPITTT--- 4043

Query: 538  STQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP--AEVKKMTAKSVPADLSR 595
            +T T   T T     +T P + + +      PT  +T           +T    P     
Sbjct: 4044 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4103

Query: 596  PKS---TSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSA 646
            P +   T+T+++  T T +GT  P    + +    TP P+      P+TTP       + 
Sbjct: 4104 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4163

Query: 647  KPSST---TPRLSRLATNTS 663
             P+ T   TP  + + T T+
Sbjct: 4164 TPTPTGTQTPTTTPITTTTT 4183



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 63/246 (25%), Positives = 92/246 (37%), Gaps = 31/246 (12%)

Query: 422  TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP----TSLPKQPAPTTIGGLNKKPMS 477
            TP   + P +    T    T  P  T T    T P    T++   P PT        P++
Sbjct: 4097 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4156

Query: 478  LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK 537
              + + P   P      +  P I  +  V P P           +P+   + P + +   
Sbjct: 4157 TTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTP-----------TPTGTQTGPPTHT--- 4201

Query: 538  STQTVAKTTTA--AAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSR 595
            ST  +A+ TT+     +ST  +SRS S+ L +  T + T     E   MT+ + P+  + 
Sbjct: 4202 STAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIE---MTSTAPPSTPTA 4258

Query: 596  PKSTS----TSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSST 651
            P +TS     S    TTT     P  G       A P PS   TT      PT    S  
Sbjct: 4259 PTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSA-PTPSTVQTTTTSAWTPTPTPLS-- 4315

Query: 652  TPRLSR 657
            TP + R
Sbjct: 4316 TPSIIR 4321



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 60/259 (23%), Positives = 92/259 (35%), Gaps = 36/259 (13%)

Query: 419  DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSL 478
            +  T P      + E  T P  TT P  T+T+   T PT    Q   TT       P++ 
Sbjct: 1877 ECVTQPTTMTTTTTENPTPP--TTTPITTTTTVTPT-PTPTGTQTPTTT-------PITT 1926

Query: 479  ASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-----ADAKAPEKRASPSKPASAPASR 533
             + + P   P      +  P I  +  V P P           P    +   P   P   
Sbjct: 1927 TTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 1982

Query: 534  SGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADL 593
            +G+++  T   TTT     +  P+     T  P   T   T   P      T  + P   
Sbjct: 1983 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPI-- 2039

Query: 594  SRPKSTSTSSMKKTTTLSGT-APAAGVVPSRVKATPMPS-----RPSTTPFIDKKPTSAK 647
                 T+T+++  T T +GT  P    + +    TP P+      P+TTP       +  
Sbjct: 2040 -----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2094

Query: 648  PSST---TPRLSRLATNTS 663
            P+ T   TP  + + T T+
Sbjct: 2095 PTPTGTQTPTTTPITTTTT 2113



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 59/247 (23%), Positives = 87/247 (35%), Gaps = 20/247 (8%)

Query: 411  PVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPT-TIG 469
            P  +GT    TTP       +P        T  P  TST+      TS P   + T    
Sbjct: 4165 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTS 4224

Query: 470  GLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRAS-PSKPAS 528
                 P++ ++ L+   PP     ++A PS   +          +  P    S P  P  
Sbjct: 4225 RSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTR 4284

Query: 529  APASRSGSKSTQTVAKTTTAAAVASTGPSSRSPS----TLLPKKPTAI-------KTEGK 577
               + S S  T +  +TTT +A   T     +PS    T L   P+++        T   
Sbjct: 4285 GTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYA 4344

Query: 578  PAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTP 637
            P E                  + T      +  S  +P     P+  K+TP PS+PS+TP
Sbjct: 4345 PGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSP----TPTPSKSTPTPSKPSSTP 4400

Query: 638  FIDKKPT 644
                KPT
Sbjct: 4401 ---SKPT 4404



 Score = 37.7 bits (86), Expect = 0.043
 Identities = 26/77 (33%), Positives = 33/77 (42%), Gaps = 5/77 (6%)

Query: 582  KKMTAKSVPADLSRPKSTSTSSMKKTTTLS-----GTAPAAGVVPSRVKATPMPSRPSTT 636
            K +T  S P     P  TST+++  TTT S      T P     PS    T     P+TT
Sbjct: 1394 KCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTT 1453

Query: 637  PFIDKKPTSAKPSSTTP 653
            P      T+  P +TTP
Sbjct: 1454 PSPPISTTTTPPPTTTP 1470


>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
          Length = 984

 Score = 77.0 bits (188), Expect = 6e-14
 Identities = 117/486 (24%), Positives = 190/486 (39%), Gaps = 58/486 (11%)

Query: 340 TPQKMTEKSESKTPGE-GKKEDKSRMAEPMKGY---MRPTKSRGLT------PLLPKSTI 389
           TP+K    +   TPG  G+++ K ++    +G    + P    G +       L  K+++
Sbjct: 220 TPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASL 279

Query: 390 QEQERHKQLKSAGIARPEEGRPVVSGTGNDIT-------TPPNKELPPSPE------KKT 436
           Q   +  + KS   +      P ++      T       +PP   L PS        KK 
Sbjct: 280 QWFNQALEDKSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKM 339

Query: 437 KPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKK--PMSLASGLVPAAPPKRPAVA 494
           +   +  P   S   A T+  S PK P+     GL++   P  L S    + PP      
Sbjct: 340 QTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGL 399

Query: 495 SARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAST 554
              PS++P+ D K  P   A+   K  + S P+ AP  +S    TQ  + ++ AA  AS+
Sbjct: 400 IPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAP-KQSFLFGTQNTSPSSPAAPAASS 458

Query: 555 GPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTA 614
            P    P    P K    + EG       +TA + P+  S P +TST++       S   
Sbjct: 459 APPMFKPIFTAPPKS---EKEGPTPPGPSVTA-TAPSSSSLPTTTSTTAPTFQPVFSSMG 514

Query: 615 PAAGVVPSRVKATPMPSRPSTTPFIDKKPTSA-KPSSTTPRLSRLATNTSAPDLKNVRSK 673
           P A V        P+P+     PF  +  T A  P++T P  + LA+ TSA  +  + S 
Sbjct: 515 PPASV--------PLPA-----PFFKQTTTPATAPTTTAPLFTGLASATSA--VAPITSA 559

Query: 674 VGSTENI-KHQPGGGRVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEK 732
             ST++  K   G G   + +  V  +  ++   S+  +   P       ++   +F   
Sbjct: 560 SPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAP-------QASAASF--- 609

Query: 733 AQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLN 792
               +GS+   G  PA     T    S++     P A    A   +   +   TSA   +
Sbjct: 610 -TPAMGSIFQFGKPPALPTTTTVTTFSQSLHTAVPTATSSSAADFSGFGSTLATSAPATS 668

Query: 793 GHPTLS 798
             PTL+
Sbjct: 669 SQPTLT 674



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 147/698 (21%), Positives = 237/698 (33%), Gaps = 128/698 (18%)

Query: 65  PDTLAKNGQEIAPAQISKSLMVDNYTKDGVPGQERPK--------GPSAVVPSTSTGGVA 116
           PD  AK     A  +  K   V+   +  + GQE  +        G SA  P  + G  A
Sbjct: 39  PDPCAKETVLSALKEKEKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVANGVPA 98

Query: 117 --LPITTAIET-VNIHGDHSLKNKAELADSMKNEAGIDEGHVIGESESVHSGASKHSVEK 173
             +P   +++  +N        NK   + SM +  G     +   S +  + +S  S   
Sbjct: 99  SFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYASGIPSSSRNAIT-SSYSSTRG 157

Query: 174 VTELAKGHLLPGVPVEDQSLPGEARALEGYADRGNFPAHPVNEEKETKEGSVAVQIPDLL 233
           +++L K +   G      S P  +R+          PA  + EE+     S +  +    
Sbjct: 158 ISQLWKRN---GPSSSPFSSPASSRS-----QTPERPAKKIREEELCHHSSSSTPLAADR 209

Query: 234 EDKAQKLSFCEDQNAQDRNSK---GSDSLNKKVDLTLLSPKSENDKLK---EISLACKIT 287
           E + +K +    +  Q+ NS+   GS    K+    L S + E   L    ++  +    
Sbjct: 210 ESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAE 269

Query: 288 ELESVSLPTPEIQSDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKD------------ 335
           +L+     + +  +  L  K +A  + V +T  I   S    LP                
Sbjct: 270 DLDLEKKASLQWFNQALEDKSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPST 329

Query: 336 -------KILETPQKMTEKSES------------KTP------GEGKKEDKSRMAEPMKG 370
                  K ++TP  +    ES            KTP      G  +      +  P   
Sbjct: 330 NPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFD 389

Query: 371 YMRPTKSRGLTP---LLPKS------TIQEQERHK-QLKSAGIARPEEGRPVVSGTGNDI 420
              PT   GL P   ++P +      T+Q +   K Q  SA    P++    + GT N  
Sbjct: 390 SKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQS--FLFGTQNTS 447

Query: 421 TTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPA----PTTIGGLNKKPM 476
            + P      S     KP+ T  P           P+     P+    PTT         
Sbjct: 448 PSSPAAPAASSAPPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQ 507

Query: 477 SLASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-------ADAKAPEKRASPSKP-AS 528
            + S + P A    PA    + +   +      P+         A AP   ASPS   AS
Sbjct: 508 PVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSAS 567

Query: 529 APASRSG--SKSTQTVAKTTTAAAVAST----GPSSRSPSTLLPKKPTAIKTEGKPAEVK 582
            PA   G  S S+ +V+ TT+ A  AS     G    S ++  P   +  +  GKP  + 
Sbjct: 568 KPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQF-GKPPALP 626

Query: 583 KMT-------------------------------AKSVPADLSRPKSTSTSSMKKTTTLS 611
             T                               A S PA  S+P  T +++   T  + 
Sbjct: 627 TTTTVTTFSQSLHTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIP 686

Query: 612 GTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPS 649
             + A   +PS   A P P+  +      + P +AKP+
Sbjct: 687 FGSSAKSPLPSYPGANPQPAFGAAE---GQPPGAAKPA 721


>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
          Length = 987

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 116/486 (23%), Positives = 188/486 (38%), Gaps = 58/486 (11%)

Query: 340 TPQKMTEKSESKTPGE-GKKEDKSRMAEPMKGY---MRPTKSRGLT------PLLPKSTI 389
           TP+K    +   TPG  G+++ K ++    +G    + P    G +       L  K+++
Sbjct: 220 TPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASL 279

Query: 390 QEQERHKQLKSAGIARPEEGRPVVSGTGNDIT-------TPPNKELPPSPE------KKT 436
           Q   +  + KS   +      P  +      T       +PP   L PS        KK 
Sbjct: 280 QWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKM 339

Query: 437 KPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKK--PMSLASGLVPAAPPKRPAVA 494
           +   +  P   S   A T+  S PK P+     GL++   P  L S    + PP      
Sbjct: 340 QTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGL 399

Query: 495 SARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAST 554
              PS++P+ D K  P   A+   K  + S P+ AP  +S    TQ  + ++ AA  AS+
Sbjct: 400 IPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAP-KQSFLFGTQNTSPSSPAAPAASS 458

Query: 555 GPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTA 614
                 P    P K    + EG       +TA + P+  S P +TST++       S   
Sbjct: 459 ASPMFKPIFTAPPKS---EKEGPTPPGPSVTA-TAPSSSSLPTTTSTTAPTFQPVFSSMG 514

Query: 615 PAAGVVPSRVKATPMPSRPSTTPFIDKKPTSA-KPSSTTPRLSRLATNTSAPDLKNVRSK 673
           P A V        P+P+     PF  +  T A  P++T P  + LA+ TSA  +  + S 
Sbjct: 515 PPASV--------PLPA-----PFFKQTTTPATAPTTTAPLFTGLASATSA--VAPITSA 559

Query: 674 VGSTENI-KHQPGGGRVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEK 732
             ST++  K   G G   + +  V  +  ++   S+  +   P       ++   +F   
Sbjct: 560 SPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAP-------QASAASF--- 609

Query: 733 AQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLN 792
               +GS+   G  PA     T    S++     P A    A   +   +   TSA   +
Sbjct: 610 -TPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATS 668

Query: 793 GHPTLS 798
             PTL+
Sbjct: 669 SQPTLT 674



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 157/715 (21%), Positives = 249/715 (34%), Gaps = 129/715 (18%)

Query: 65  PDTLAKNGQEIAPAQISKSLMVDNYTKDGVPGQERPK--------GPSAVVPSTSTGGVA 116
           PD  AK     A  +  K   V+   +  + GQE  +        G SA  P  ++G  A
Sbjct: 39  PDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPA 98

Query: 117 --LPITTAIET-VNIHGDHSLKNKAELADSMKNEAGIDEGHVIGESESVHSGASKHSVEK 173
             +P   +++  +N        NK   + SM +  G     +   S +  + +S  S   
Sbjct: 99  SFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAIT-SSYSSTRG 157

Query: 174 VTELAKGHLLPGVPVEDQSLPGEARALEGYADRGNFPAHPVNEEKETKEGSVAVQIPDLL 233
           +++L K +   G      S P  +R+          PA  + EE+     S +  +    
Sbjct: 158 ISQLWKRN---GPSSSPFSSPASSRS-----QTPERPAKKIREEELCHHSSSSTPLAADK 209

Query: 234 EDKAQKLSFCEDQNAQDRNSK---GSDSLNKKVDLTLLSPKSENDKLK---EISLACKIT 287
           E + +K +    +  Q+ NS+   GS    K+    L S + E   L    ++  +    
Sbjct: 210 ESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAE 269

Query: 288 ELESVSLPTPEIQSDFLHSKVEAPPSEVADTL------------VIMTASKGVRLPEPKD 335
           +L+     + +  +  L  K +A  + V +T                TAS    L  P  
Sbjct: 270 DLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPST 329

Query: 336 -------KILETPQKMTEKSES------------KTP------GEGKKEDKSRMAEPMKG 370
                  K ++TP  +    ES            KTP      G  +      +  P   
Sbjct: 330 NPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFD 389

Query: 371 YMRPTKSRGLTP---LLPKS------TIQEQERHK-QLKSAGIARPEEGRPVVSGTGNDI 420
              PT   GL P   ++P +      T+Q +   K Q  SA    P++    + GT N  
Sbjct: 390 SKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQS--FLFGTQNTS 447

Query: 421 TTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPA----PTTIGGLNKKPM 476
            + P      S     KP+ T  P           P+     P+    PTT         
Sbjct: 448 PSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQ 507

Query: 477 SLASGLVPAAPPKRPAVASARPSILPSKDVKPKPI-------ADAKAPEKRASPSKP-AS 528
            + S + P A    PA    + +   +      P+         A AP   ASPS   AS
Sbjct: 508 PVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSAS 567

Query: 529 APASRSG--SKSTQTVAKTTTAAAVAST----GPSSRSPSTLLPK--------KPTAIKT 574
            PA   G  S S+ +V+ TT+ A  AS     G    S ++  P         KP A+ T
Sbjct: 568 KPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPT 627

Query: 575 --------EGKPAEVKKMT--------------AKSVPADLSRPKSTSTSSMKKTTTLSG 612
                   +  P  V   T              A S PA  S+P  T +++   T  +  
Sbjct: 628 TTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPF 687

Query: 613 TAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLAT--NTSAP 665
            + A   +PS   A P P+  +      + P +AKP + TP      T  N++AP
Sbjct: 688 GSSAKSPLPSYPGANPQPAFGAAE---GQPPGAAKP-ALTPSFGSSFTFGNSAAP 738


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 84/345 (24%), Positives = 120/345 (34%), Gaps = 47/345 (13%)

Query: 326  KGVRLPEPKDKILETPQKMTEKS---ESKTPGEGKKEDKSRMAEPMKGYMR--PTKSRGL 380
            KG   P+     L +P    E S   E+    +G K+  +    P     +  PT S  +
Sbjct: 812  KGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPS-AV 870

Query: 381  TPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLA 440
            TPL PK               G+  P +  P    T + +  P  KE P +P  K  P  
Sbjct: 871  TPLSPK---------------GVTLPPKETP----TPSVVNLPFPKEGPATPAPKQAPAL 911

Query: 441  TTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSI 500
            +   +    ++A   P  +P  P+P        K         P +P   PA  S + + 
Sbjct: 912  SMTSSSPKKARATPAPKGIPASPSP--------KGAPTPPAATPPSPKGGPATPSPKWAP 963

Query: 501  LPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRS 560
             P     P P      P  + +P+ PA+ P S  G  +T +     T  AV    P    
Sbjct: 964  TPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP 1023

Query: 561  PSTLLPK----KPTAIKTEGKPAEVKKMTAKSVP----ADLSRPK-STSTSSMKKTTT-- 609
             +T  PK     P A     K +       K  P    A L  PK   +T S+K   T  
Sbjct: 1024 AATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPP 1083

Query: 610  -LSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTP 653
              +  +P  G      K  PMP  P+ TP   K   +  P    P
Sbjct: 1084 AATPPSPKGGPATPSPKGAPMP--PAATPPSPKGGLATPPHKGAP 1126



 Score = 71.2 bits (173), Expect = 4e-12
 Identities = 97/398 (24%), Positives = 126/398 (31%), Gaps = 56/398 (14%)

Query: 311  PPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEKSESKTPGE---GKKEDKSRMAEP 367
            PP + A T    T       P PK  +   P K    + + TP     G      + A  
Sbjct: 1143 PPPKGAPTTPAATP------PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPT 1196

Query: 368  MKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPE-EGRPVV------SGTGNDI 420
                  P+   GL    PK               G+A P  +G P        S  G   
Sbjct: 1197 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPA 1256

Query: 421  TTPPNKELPPSPEKKTKP-----LATT------QPAKTSTSKAKTQPTSLPKQPAPTTIG 469
            T PP     P+P   T P     LAT        PA  +    K  P + P + APT   
Sbjct: 1257 TPPPKGA--PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPA 1314

Query: 470  GLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVK-PKPIADAKAPEKRASPSKPAS 528
                 P        P   P  PAV    P   P+     P        P  +  P+ PA+
Sbjct: 1315 ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAA 1374

Query: 529  APASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKK--PTAIKTEG---------K 577
             P+ + G   T    K   A       P+S +   L PKK   T +  EG          
Sbjct: 1375 TPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLT 1434

Query: 578  PAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAP------------AAGVVPSRVK 625
            P  V  ++ K  PA  +     +T S K   TL    P            A    P +  
Sbjct: 1435 PPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAP 1494

Query: 626  ATPMPSRPSTTPFI---DKKPTSAKPSSTTPRLSRLAT 660
            ATP P    T P +     K   A PSS    ++  AT
Sbjct: 1495 ATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT 1532



 Score = 70.9 bits (172), Expect = 5e-12
 Identities = 117/493 (23%), Positives = 166/493 (33%), Gaps = 57/493 (11%)

Query: 213  PVNEEKETKEGSVAVQIP--DLLEDKAQ-KLSFCEDQNAQDRNSKGSDSLNKKVDLTLLS 269
            P  +   TK+GS     P  +L    +  + SF  + +   + SK S +       T  S
Sbjct: 803  PQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSP--TPPS 860

Query: 270  PKSENDKLKEISLACKITELESVSLPTPEIQSDFLHSKVEAPPSEVADTLVIMTAS---K 326
            PK          L+ K   L     PTP + +     +  A P+      + MT+S   K
Sbjct: 861  PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK 920

Query: 327  GVRLPEPKD-------KILETPQKMTEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRG 379
                P PK        K   TP   T  S    P  G      + A        P+   G
Sbjct: 921  ARATPAPKGIPASPSPKGAPTPPAATPPS----PKGGPATPSPKWAPTPPAATPPSPKGG 976

Query: 380  LTPLLPKSTIQEQERHKQLKSAGIARPE---------------EGRPVVSGTGNDITTPP 424
                 PK               G A P                +G P  +      +TPP
Sbjct: 977  PATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPP 1036

Query: 425  NKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQ-PAPTTIGGLNKKPMSLASGLV 483
                PPSP  K  P AT  P    T+ A T P+  PK  PA  ++ G    P +      
Sbjct: 1037 -AATPPSP--KGSPAATPLPKGAPTTPAATLPS--PKGGPATPSLKGAPTPPAA-----T 1086

Query: 484  PAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTV- 542
            P +P   PA  S + + +P     P P      P  + +P+ PA+ P S  G  +T    
Sbjct: 1087 PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPK 1146

Query: 543  -AKTTTAAAVAS------TGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSR 595
             A TT AA   S      T P   +P+T     P+       P+     T  +      +
Sbjct: 1147 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1206

Query: 596  PKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRL 655
                + S     TT + T P+    P    ATP P    TTP          P++  P+ 
Sbjct: 1207 GGLATPSPKGAPTTPAATPPS----PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKG 1262

Query: 656  SRLATNTSAPDLK 668
            +      + P LK
Sbjct: 1263 APTPPAATPPSLK 1275



 Score = 70.9 bits (172), Expect = 5e-12
 Identities = 117/497 (23%), Positives = 164/497 (32%), Gaps = 53/497 (10%)

Query: 331  PEPKDKILETPQKMTEKSESKTPGEGKKEDKSRMAEP-MKGYMRPTKSRGLTPL------ 383
            P PK     TP     K    TP       K   A P +KG   P  +   +P       
Sbjct: 1041 PSPKGSPAATP---LPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097

Query: 384  LPKSTIQEQERHKQLKSAGIARP-EEGRPVVSGTG-----NDITTPPNKELPPSPEKKTK 437
             PK               G+A P  +G P             + TPP K  P +P   T 
Sbjct: 1098 SPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA-TP 1156

Query: 438  P-----LATTQPAKTSTSKAKTQPT-----------SLPKQPA---PTTIGGLNKKPMSL 478
            P     LAT  P    T+ A T P+             P  PA   P+  GGL   P   
Sbjct: 1157 PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL-ATPSPK 1215

Query: 479  ASGLVPAAPPKRP--AVASARPSILPSKDVK--PKPIADAKAPEKRASPSKPASAPASRS 534
             +   PAA P  P   +A+  P   P+      P P      P  + +P+ PA+ P S  
Sbjct: 1216 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLK 1275

Query: 535  GSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLS 594
            G  +T         A V  T PS +      P K         P   K       P    
Sbjct: 1276 GGLATPPHKGAPNPAVV--TPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAP 1333

Query: 595  RPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPS-STTP 653
             P + +  S K T TL  T P++   P+   +   P+ P+ TP     P    PS    P
Sbjct: 1334 TPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGP 1393

Query: 654  RLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSKANIKH 713
             +     + ++P +  +  K      +  +      +       ++ VS K   KA    
Sbjct: 1394 AIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLK---KAPATS 1450

Query: 714  KPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGP-PAGEE 772
             P GG     S     K        +  +    PA   V T     +AP  P P  A   
Sbjct: 1451 APKGGPATPSS-----KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTL 1505

Query: 773  PAISEAAPEAGAPTSAS 789
            PA+  ++P+    T +S
Sbjct: 1506 PAVIPSSPKEVPATPSS 1522



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 97/417 (23%), Positives = 147/417 (35%), Gaps = 72/417 (17%)

Query: 326  KGVRLPEPKDKILETPQKMTEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLP 385
            +G  +P PK     T   +   S  K P      + +  A P KG + P     +TP+  
Sbjct: 1391 RGPAIPSPKGD--PTSPAVIPLSPKKAPATPVTREGA--ATPSKGDLTPP---AVTPV-- 1441

Query: 386  KSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDIT----TPPNKELPPSPEK-KTKPLA 440
                        LK A      +G P    +  D T    TPP+ + PP+P++  T    
Sbjct: 1442 -----------SLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP 1490

Query: 441  TTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSI 500
               PA  +   A T P  +P  P         + P + +S   P AP     ++   P+ 
Sbjct: 1491 KKAPATPAPMGAPTLPAVIPSSP--------KEVPATPSSRRDPIAPTAT-LLSKKTPAT 1541

Query: 501  LPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAST------ 554
            L  K+    P     +P+K  +   P  APA+ S  +++   A T +    A +      
Sbjct: 1542 LAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLI 1601

Query: 555  GPSSRSPSTLLPKKPTAI----KTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTL 610
             P+  SPS      P A+      +G      K T  S P   S  K + TS    T  +
Sbjct: 1602 PPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKM 1661

Query: 611  SGTAPAAG------VVPSRVKATPMPSRPSTTPFID----KKPTSAKPSSTTPRLSRLAT 660
              T P A         P+ +K   +   P +TP I     K P + K S+T+P +     
Sbjct: 1662 GATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPI----- 1716

Query: 661  NTSAPDLKNVRSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSKANIKHKPGG 717
                PD        G    +   P           + + K SSK     +  H P G
Sbjct: 1717 ---CPDPSAKNGSKGPLSTVAPAP----------LLPVQKDSSKTAKGKDASHSPKG 1760



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 69/242 (28%), Positives = 94/242 (38%), Gaps = 20/242 (8%)

Query: 429 PPSPEKKT-KPLATTQPAKTSTSK-AKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAA 486
           PP P+ +  K L ++   K  T K  +T P SL   P      GL  K       LV AA
Sbjct: 507 PPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAA 566

Query: 487 PPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTT 546
           P   P+  S   S  P   + P+     K+  +     KPAS+  S  G  S+ +V KT 
Sbjct: 567 PKNSPSFQSTSSS--PEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTD 624

Query: 547 TAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAK--SVPADLSRPKSTSTSSM 604
           + A   S GP  +S S + P           PA V   TAK  S     + P    T S+
Sbjct: 625 SYAGPDSAGPLLKS-SLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSL 683

Query: 605 --KKTTTLSGTAPAAGVVPSRVKATPMPSRPSTT----------PFIDKK-PTSAKPSST 651
             K      GT     +VP+  +  P+   P  T          P I K  P+ + P + 
Sbjct: 684 APKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAG 743

Query: 652 TP 653
           TP
Sbjct: 744 TP 745



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 92/418 (22%), Positives = 148/418 (35%), Gaps = 65/418 (15%)

Query: 293  SLPTPEIQSDFLHSK-VEAPPSEVADTLVIMTASKGVRLP----EPKDKILETPQKMTEK 347
            ++PTP+       SK   +PP+    T     + K + +P     P  K   TP  +T  
Sbjct: 1563 AIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPP 1622

Query: 348  SESKTPGEG--KKEDKSRMAEPMKGYMRPTKSRGLT----PLLPKST--IQEQERHKQLK 399
            S  K P     K    S    P      PT    +T      +P+++  +  ++    LK
Sbjct: 1623 SPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALK 1682

Query: 400  SAGIARPEEGRPVVSGTG--------NDITTPPNKELPPSPEKKTKPLATTQPA------ 445
               +A   E  P+++           +  T+PP    P +      PL+T  PA      
Sbjct: 1683 EVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQ 1742

Query: 446  KTSTSKAKTQPTS-LPKQP---------APTTIGGLNK---KPMSLASGLVPAAPPKRPA 492
            K S+  AK +  S  PK P          P T     K   KP S +    P+ P   P 
Sbjct: 1743 KDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPL 1802

Query: 493  VASARPSILPSKDVKP-KPIADAKAPEKRASPSK-----PASAPASRSGSKSTQTV---A 543
              S  P++ P +   P  P    ++P K  +P+      P   P   SG    Q+V    
Sbjct: 1803 APSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNM 1862

Query: 544  KTTTAAAVASTGPSSRSPST--------------LLPKKPTAIKTEGKPAEVKKMTAKSV 589
             T  +A +    PS++ P T               +P+      T+    + +   A  +
Sbjct: 1863 PTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEI 1922

Query: 590  PAD-LSRPK-STSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTS 645
              + +S+ K S S    +K  +  G     GV    ++ +       T P + K P S
Sbjct: 1923 DEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPAS 1980



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 68/266 (25%), Positives = 109/266 (40%), Gaps = 32/266 (12%)

Query: 436 TKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVAS 495
           T PL  T P   + +   T   +    P  ++    N +P S A+ ++    PK P+   
Sbjct: 438 TTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQV 497

Query: 496 A-------RPSILPSKDVKPKPIAD-AKAPEKRASPSKPAS---APASRS----GSKSTQ 540
           A        P +   +D+K  P +   K P ++   + PAS   AP S +     +K   
Sbjct: 498 ATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDP 557

Query: 541 TVAKTTTAAAVASTGPSSRSPSTLLPKKPTAI---KTEGKPAEVKKMTAKSVPADLSRPK 597
           TV     AA   S    S S S  +P  P A    K+ G+P  + K  A S+ + L    
Sbjct: 558 TVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGK-PASSMTSPLG--- 613

Query: 598 STSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRP--STTPFIDKKPTSAKPSSTTPRL 655
             S++S+ KT + +G   A  ++ S +    + + P  S  P     PT+AK +ST    
Sbjct: 614 VNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADP-AGVAPTTAKGTST---- 668

Query: 656 SRLATNTSAPDLKNVRSKVGSTENIK 681
               T T++P L+   S       +K
Sbjct: 669 ---YTTTASPFLEGTVSLAPKNHPVK 691



 Score = 38.1 bits (87), Expect = 0.033
 Identities = 89/404 (22%), Positives = 144/404 (35%), Gaps = 55/404 (13%)

Query: 427 ELPPSPEKKTKP--LATTQPAKTSTSKAKTQP--TSLPKQPAPTT---IGGLNKKPMSLA 479
           E+ P+P+    P  + +T P    T  A  Q    SLP Q  PTT   I     K  +++
Sbjct: 194 EVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLP-QTTPTTTLAIASPQVKDTTIS 252

Query: 480 SGLVPAAPPKRPAVASARPSILP--SKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK 537
           S L+    P+ P   S +  + P  +  +  + +    + +K A P+ P   P S     
Sbjct: 253 SVLIS---PQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHL 309

Query: 538 STQTVAKTTTAAAVASTGPSSRS------------------PSTLLPKKPTAIKTEGKPA 579
           +    +   +   +  TGPS+ S                  PS      P   + E  PA
Sbjct: 310 APLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPA 369

Query: 580 EVK--KMTAKSV---PADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKAT------- 627
            V    + A SV   P+ +S    + + S+   T+ S +   + ++ S   AT       
Sbjct: 370 TVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVA 429

Query: 628 PMP-SRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGG 686
            MP S   TTP +   P +   + TT     +AT  S P      S +  T         
Sbjct: 430 QMPVSSVGTTPLVVTNPCTIAAAPTT--TFEVATCVSPPMSSGPISNIEPTSPAALVMAP 487

Query: 687 GRVQIQNKKVDIS---KVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNV 743
              +  + +V  +    VS       ++K+ P    VK  +QK       Q    SL+  
Sbjct: 488 VAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQK-----DLQTVPASLEGA 542

Query: 744 GHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTS 787
              PA   + T+   +  PL    P    P+    +     P S
Sbjct: 543 PFSPAQAGLTTKKDPTVLPLVQAAPK-NSPSFQSTSSSPEIPLS 585


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 104/481 (21%), Positives = 172/481 (35%), Gaps = 37/481 (7%)

Query: 326 KGVRLPEPKDKILETPQKMTEKSESKTPGEGKKEDKSRM-AEPMKGYMRPTKSRGLTPLL 384
           K  ++PE K +      K  +K  S +  E   E++  +   P K    P K  GL P  
Sbjct: 59  KSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGK 118

Query: 385 PKSTIQEQERHKQLKSAGIARPEEGRPVVSGT---GNDITTPPNK----ELPPSPEKKTK 437
             +   E    ++         ++ +PV  G          PP K    +       + +
Sbjct: 119 AAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDE 178

Query: 438 PLATTQPAKTS-TSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASA 496
           P    +P  T  T KA+T+    P + AP    G      S +S    +   +    A+ 
Sbjct: 179 PPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAAT 238

Query: 497 RPSILPSKDVKPK-PIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTG 555
               +P K V  K P+  A  P +++S S+ +S+       K  +              G
Sbjct: 239 PKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKN-----------KPG 287

Query: 556 PSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAP 615
           P S  P    P    ++ T+     V+K        D S    +S+   KK  T +  + 
Sbjct: 288 PYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSK 347

Query: 616 AAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLS-RLATNTSAPDLKNVRSKV 674
           A    P   KA    S  S +   +     +KP+ TT   S + A  T +P +K   +  
Sbjct: 348 ATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAA-- 405

Query: 675 GSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIES---QKLNFKE 731
                   QP GG  ++  +K D S    +  S    K K      K ++     L+   
Sbjct: 406 ------PKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPA 459

Query: 732 KAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGP---PAGEEPAISEAAPEAGAPTSA 788
           K QA  GS D+     +  + + E   S++ +   P     G  P+   +A +  A +S 
Sbjct: 460 K-QAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSN 518

Query: 789 S 789
           S
Sbjct: 519 S 519



 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 91/422 (21%), Positives = 155/422 (36%), Gaps = 30/422 (7%)

Query: 194 PGEARALEGYADRGNFPAHPVNEEKETKEGSVAVQIPDLLEDKAQKLSFCEDQNAQDRNS 253
           PG+A A    +      +   +EE + K+       P     KA         +  D +S
Sbjct: 116 PGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSS 175

Query: 254 KGSDSLNKKVDLTLLSPKSENDKL-KEISLACKITELESVSLPTPEIQS----DFLHSKV 308
           +     N+K  +T ++ K++     K    A KI   ++ S  +    S    D    K 
Sbjct: 176 EDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKA 235

Query: 309 EAPPSEVADTLVIMTAS--KGVRLPEPKDKILETPQKMTEKSESKTPGEGKKEDKSRMAE 366
            A P +      ++  +  K    P  K    E      E+ E K P + K    S +  
Sbjct: 236 AATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSS-DEEEEQKKPMKNKPGPYSSVPP 294

Query: 367 PMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAG----IARPEEGRPVVSGTGNDITT 422
           P      P KS G  P  PK  +++Q+  +  + +      +  EE +P      +  TT
Sbjct: 295 PSAP--PPKKSLGTQP--PKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATT 350

Query: 423 PPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGL 482
            P       P KK       + +  S+    ++    P +PA TT    NK  ++  S  
Sbjct: 351 KP------PPAKKA-----AESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPA 399

Query: 483 V-PAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQT 541
           V PAA PK+P     +  +L  K        ++ + E+  +    A+     +   +   
Sbjct: 400 VKPAAAPKQPVGGGQK--LLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSL 457

Query: 542 VAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTST 601
            AK     +  S+  S  S S    +K +    + KP +V    A S PA   + K+ S+
Sbjct: 458 PAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESS 517

Query: 602 SS 603
           +S
Sbjct: 518 NS 519



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 79/376 (21%), Positives = 133/376 (35%), Gaps = 49/376 (13%)

Query: 479 ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRAS-PSKPASAPASRSGS- 536
           A+G V     K+ + + +  S    ++V+  P   A  P KR   P   A+A AS S S 
Sbjct: 70  ANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSS 129

Query: 537 ------------------KSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP 578
                             K  +  AK   A    +    S S S+   + P   K +  P
Sbjct: 130 EESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITP 189

Query: 579 AEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPF 638
             VK  T        + PK  +  +   +++ S ++ +      +  ATP  + P     
Sbjct: 190 VTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPK-KQV 248

Query: 639 IDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGG-GRVQIQNKKVD 697
           + K P  A   +TTP     ++  S+ D +  + K      +K++PG    V   +    
Sbjct: 249 VAKAPVKA---ATTPTRKSSSSEDSSSDEEEEQKK-----PMKNKPGPYSSVPPPSAPPP 300

Query: 698 ISKVSSKCGSKANIKHKP--GGGDVKIESQKLNFKEKAQAKVGSLDNVGHLP-------A 748
              + ++   KA  K +P     D   ES   + +EK       +      P        
Sbjct: 301 KKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAE 360

Query: 749 GGAVKTEGGGSEAPLCPGPPAG------EEPAISEAAP---EAGAPTSASGLNGHPTLSG 799
             +  ++   SE    P  PAG       +PA++  +P    A AP    G  G   L+ 
Sbjct: 361 SSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVG-GGQKLLTR 419

Query: 800 GGDQREAQTLDSQIQE 815
             D   ++   S  +E
Sbjct: 420 KADSSSSEEESSSSEE 435


>gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo
           sapiens]
          Length = 834

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 115/486 (23%), Positives = 187/486 (38%), Gaps = 58/486 (11%)

Query: 340 TPQKMTEKSESKTPGE-GKKEDKSRMAEPMKGY---MRPTKSRGLT------PLLPKSTI 389
           TP+K    +   TPG  G+++ K ++    +G    + P    G +       L  K+++
Sbjct: 69  TPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASL 128

Query: 390 QEQERHKQLKSAGIARPEEGRPVVSGTGNDIT-------TPPNKELPPSPE------KKT 436
           Q   +  + KS   +      P ++      T       +PP   L PS        KK 
Sbjct: 129 QWFNQALEDKSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKM 188

Query: 437 KPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKK--PMSLASGLVPAAPPKRPAVA 494
           +   +  P   S   A T+  S PK P      GL++   P  L S    + PP      
Sbjct: 189 QTPPSLPPCPESAGAATTEALSPPKTPNLLPPLGLSQSGPPGLLPSPSFDSNPPTTLLGL 248

Query: 495 SARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAST 554
              PS++P+ D K  P   A+   K  + S P+ AP  +S    TQ  + ++ AA  AS+
Sbjct: 249 IPAPSMVPATDTKAPPTLQAETTTKPQATSAPSPAP-KQSFLFGTQNTSPSSPAAPAASS 307

Query: 555 GPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTA 614
                 P    P K    + EG P       + + P+  S P +TST++       S   
Sbjct: 308 ASPMFKPIFTAPPKS---EKEG-PTPPGPSVSATAPSSSSLPTTTSTTAPTFQPVFSSMG 363

Query: 615 PAAGVVPSRVKATPMPSRPSTTPFIDKKPTSA-KPSSTTPRLSRLATNTSAPDLKNVRSK 673
           P A V        P+P+     PF  +  T A  P++T P  + LA+ TSA  +  + S 
Sbjct: 364 PPASV--------PLPA-----PFFKQTTTPATAPTTTAPLFTGLASATSA--VAPITSA 408

Query: 674 VGSTENI-KHQPGGGRVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEK 732
             ST++  K   G G   + +  V  +  ++   S+  +   P       ++   +F   
Sbjct: 409 SPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAP-------QASAASF--- 458

Query: 733 AQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLN 792
               +GS+   G  PA     T    S++     P A    A   +   +   TSA   +
Sbjct: 459 -TPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATS 517

Query: 793 GHPTLS 798
             PTL+
Sbjct: 518 SQPTLT 523



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 76/289 (26%), Positives = 106/289 (36%), Gaps = 62/289 (21%)

Query: 421 TTPPNKE----LPPSPE-KKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKP 475
           T PP  E     PP P    T P +++ P  TST+    QP      P            
Sbjct: 317 TAPPKSEKEGPTPPGPSVSATAPSSSSLPTTTSTTAPTFQPVFSSMGPP----------- 365

Query: 476 MSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP-ASAPASRS 534
              AS  +PA   K+    +  P+              A AP   ASPS   AS PA   
Sbjct: 366 ---ASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGF 422

Query: 535 G--SKSTQTVAKTTTAAAVAST----GPSSRSPSTLLPK--------KPTAIKT------ 574
           G  S S+ +V+ TT+ A  AS     G    S ++  P         KP A+ T      
Sbjct: 423 GINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTT 482

Query: 575 --EGKPAEVKKMT--------------AKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAG 618
             +  P  V   T              A S PA  S+P  T +++   T  +   + A  
Sbjct: 483 FSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKS 542

Query: 619 VVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLAT--NTSAP 665
            +PS   A P P+  +      + P +AKP + TP      T  N++AP
Sbjct: 543 PLPSYPGANPQPAFGAAE---GQPPGAAKP-ALTPSFGSSFTFGNSAAP 587


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 76/275 (27%), Positives = 98/275 (35%), Gaps = 31/275 (11%)

Query: 417 GNDITTPPNKELPPSPEKKTKPLATT--------QPAKTSTSKAKTQPTSLPKQPAPTTI 468
           G D+   P+    P P+ KT P+ TT        QP +TS  K       L K P P   
Sbjct: 647 GGDLAPVPSS---PQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKP 703

Query: 469 GGLNKKPM------------SLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKA 516
             L K+P               A  L   APPK P+V S +    P  D KPK     K 
Sbjct: 704 PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKA-PVADDKPKQPKMVKP 762

Query: 517 PEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEG 576
                S S   + P   S    +Q   KTT      S  PS   P T     P   K   
Sbjct: 763 TTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP 822

Query: 577 KPAEVKKMTAKSVPADLSRPKS-----TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPS 631
           +PA   K+ +   P+  S+ +            KK  T     P A  +P +   TP   
Sbjct: 823 RPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP-KGSPTPPGP 881

Query: 632 RPSTTPFIDKKPTSAKPSSTTPRLS-RLATNTSAP 665
           RP+    +     S KP   + R S  L + T AP
Sbjct: 882 RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAP 916



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 88/345 (25%), Positives = 129/345 (37%), Gaps = 44/345 (12%)

Query: 346 EKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLP--KSTIQEQERHKQLKSAGI 403
           EK +S+ PG GK         P++G   PT+    TP     K  +Q      Q K A I
Sbjct: 245 EKIKSQPPGTGK---------PIQG---PTQ----TPQTDHAKLPLQRDASRPQTKQADI 288

Query: 404 ARPEEGRPVVSGTGNDITTPPNKELPPSPE---KKTKPLATTQPAKTS--TSKAKTQPTS 458
            R E  +P +          P    PP+ +   +K++P     PA+ S  T     QP +
Sbjct: 289 VRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGT 348

Query: 459 L--PKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKA 516
           +  P QP  TT     K P   A  L PA PP +   +    S  P      +P    K 
Sbjct: 349 VKPPVQPPGTT-----KPP---AQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKT 400

Query: 517 PEKRASPSKPASA------PASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPT 570
           P ++  P+KP +       P ++     +   A   T   V   GP         P K +
Sbjct: 401 PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTS 460

Query: 571 AIKT-EGKPAEVKKMTAKSVPADL--SRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKAT 627
           A +T   KP       AK  P     ++P      S K  +   G+       P   K  
Sbjct: 461 AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAK-- 518

Query: 628 PMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRS 672
           P P +P +T    ++P SAKPS+  P  ++ +   S   +    S
Sbjct: 519 PSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGS 563



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 180/809 (22%), Positives = 279/809 (34%), Gaps = 113/809 (13%)

Query: 30  SELINKSSPLEVL-ESAACEKLPTPTPQVVKEGDSFPDTLAKNG-QEIAPAQISKSLMV- 86
           S ++NK +P +++ +S A ++  T   +VV++    P+ + K   Q+  P  I K     
Sbjct: 167 SSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPG 226

Query: 87  -DNYTKDGVPGQERPKGPSAVVPSTSTGGVALPITTAIETVNIHGDHS-LKNKAELADSM 144
            D   +DG P     + P  +   +   G   PI    +T     DH+ L  + + +   
Sbjct: 227 RDPLQQDGTPKSISSQQPEKI--KSQPPGTGKPIQGPTQTPQT--DHAKLPLQRDASRPQ 282

Query: 145 KNEAGIDEGHVIGESESVHSGASKHSVEKVTELAKGHLLPGVPVEDQSLPGEARALEGYA 204
             +A I  G      ESV       S   + +   G      P  ++S PG A+      
Sbjct: 283 TKQADIVRG------ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP----- 331

Query: 205 DRGNFPAHPVNEEKETKE--GSVA--VQIPDLLEDKAQKLSFCEDQNAQDRNSKGSDSLN 260
                PA P    K   +  G+V   VQ P   +  AQ L   +    Q  + K S    
Sbjct: 332 -----PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE-- 384

Query: 261 KKVDLTLLSPKSENDKLKEISLACKITELESVSLPTPEIQSDFLHSKVEAP-PSEVADTL 319
           +     L  P        +     K    + V  P P  Q   L S  +AP P++     
Sbjct: 385 QPGPKALAQPPGVGKTPAQQPGPAK-PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP--- 440

Query: 320 VIMTASKGVRLPEPKDKILETPQKMTEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRG 379
                   V+ P P     + P +     ++     G  +  S++  P K   +      
Sbjct: 441 --------VQQPGPG----KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK 488

Query: 380 LTPLLPKSTIQEQERHKQLK----SAGIARPEEGRPVVSGTGNDITTPPNKELP----PS 431
             P  P S     ++    K      G A+P   +P   G+    +  P    P    PS
Sbjct: 489 PPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQP---GSTKPPSQQPGSAKPSAQQPS 545

Query: 432 PEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKK--PMSLASGLVPAAPPK 489
           P K +   +T   ++T + K    PT  P    P +  GL K   P+   + L+   P K
Sbjct: 546 PAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPS-QGLPKTICPLCNTTELLLHVPEK 604

Query: 490 RP--AVASARPSILPSKDVKPKP-IADAK------APEKRASPSKPASAPASRSGSKSTQ 540
                    + ++       P P + + K         KRA     A  P+S      T 
Sbjct: 605 ANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT- 663

Query: 541 TVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE-GKPAEVKKMTAKSVPADLSRPKST 599
             A  TT +AV+ + P  +  S   PKK  A K +  K  E KK         L    S 
Sbjct: 664 --APVTTTSAVSKSSPQPQQTS---PKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718

Query: 600 STSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLA 659
                 +  +LS  AP         K   +PS     P  D KP   K    T  L   +
Sbjct: 719 KAKQPPEADSLSKPAPP--------KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSS 770

Query: 660 TNTSAPDLKNVRSKVGS-----------TENIK----HQPGGGRVQ-IQNKKVDISKVSS 703
           + T+ PD+ +  SKV S           T++ K      P G +V    +K +      S
Sbjct: 771 SATTKPDIPS--SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDS 828

Query: 704 KCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPL 763
           K  S      +  G       QK    +KAQ K+    +   +P          GS  P 
Sbjct: 829 KIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK---------GSPTPP 879

Query: 764 CPGPPAGEEPAISEAAPEAGAPTSASGLN 792
            P P AG+     + +P+    +    LN
Sbjct: 880 GPRPTAGQTVPTPQQSPKPQEQSRRFSLN 908



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 114/504 (22%), Positives = 169/504 (33%), Gaps = 106/504 (21%)

Query: 250  DRNSKGSDSLNKKVDLTLLSPKSENDKLKEISLACKIT-------ELESVSLPTPEIQSD 302
            D  +K  DS  +++  +   P S  D  +EIS++   T         + + +   ++ S 
Sbjct: 2215 DMITKFEDS--EEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASS 2272

Query: 303  FLHSKVEAPPSEVADTLV--IMTASKGVRLPEPKDK----ILETPQKMTEKSESKTPGEG 356
             + S V  P   VADT+   ++ + K       K+     ILE  +   +K E +     
Sbjct: 2273 IIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEA---- 2328

Query: 357  KKEDKSRMAE------PMKGYMRPTKSR-GLTPLLPKSTIQEQERHKQLKSAG---IARP 406
             +  KS ++E      P      P K +   T      T  +++   QL S      + P
Sbjct: 2329 -ERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLP 2387

Query: 407  EEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPT 466
             + RP    +  DI+  P    PP P     P     P           P   P  P PT
Sbjct: 2388 AKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPP-----------PLPPPTSPKPT 2436

Query: 467  TIGGLNKKPMSLASGLVPAAP-------------------PKRPAVASARPSILPSKDVK 507
                L KK +++AS +  A P                   P      +A P + P    K
Sbjct: 2437 I---LPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPP----K 2489

Query: 508  PKPIADAKAPEKRASPSKPASAP------ASRSGSKSTQTVAKTTTAAAVAS------TG 555
            P  I        R  PSKP  AP         +  K T    K T  +  +S      T 
Sbjct: 2490 PSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTS 2549

Query: 556  PSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADL-SRPKSTSTSSMKKTTT----- 609
               + PS   P  P + K+   P   K +T   V   L S P + + SS  +  T     
Sbjct: 2550 ADYKLPSPTSPLSPHSNKS--SPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLG 2607

Query: 610  -----LSGTAPAAGVVPSRVKATPMPSRP-------------STTPFIDKKPTSAKPSST 651
                 L    P   VVP  V A  +P                S TP        A P+S 
Sbjct: 2608 SPSKDLVSVEPVFSVVPP-VTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSV 2666

Query: 652  TPRLSRLATNTSAPDLKNVRSKVG 675
            T  L+   + T     ++    VG
Sbjct: 2667 TQFLTTEVSKTEVSATRSTAPSVG 2690



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 140/685 (20%), Positives = 231/685 (33%), Gaps = 112/685 (16%)

Query: 63   SFPDTLAKNGQEIAPAQISKSLMVDNYT---KDGVPGQERPKGPSAVVPSTSTGGVALPI 119
            S P    K       + +SKS      T   KD  P Q+  K P    P           
Sbjct: 655  SSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPP--------- 705

Query: 120  TTAIETVNIHGDHSLKNKAEL-ADSMKNEAGIDEGHVIGESESVHSGASKHS----VEKV 174
               ++   +HG  S K K    ADS+   A   E  V  E +       K      V+  
Sbjct: 706  --LVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPT 763

Query: 175  TELAKGHLL---PGVPVEDQSLPGEARALEGYADRGNFPAH--PVNEEKETKEGSVAVQI 229
            T+L         P +P        E +           P+   P   EK +   S A+  
Sbjct: 764  TDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPR 823

Query: 230  PDLLEDKAQKLSFCEDQNAQDRNSKGSDSLNKKVD----LTLLSPKSENDKLKEISLAC- 284
            P        K+      +++ +  K  D + KK +     T +SPK +   + + S    
Sbjct: 824  PA----SDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP 879

Query: 285  --KITELESVSLPT----PEIQSDF----LHSKVEAP---PSEVADTLVIMTASKGVRLP 331
              + T  ++V  P     P+ QS      L S  +AP   P+   +T+       G  + 
Sbjct: 880  GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIF 939

Query: 332  EPKDKILETPQKMTEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQE 391
                 ++ T  +    S+S  PG   K+  +    P      P KS G  P  P  +I  
Sbjct: 940  SQASNLISTAGQPGPHSQSG-PGAPMKQAPAPSQPPTS--QGPPKSTGQAPPAPAKSIPV 996

Query: 392  QERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSK 451
            ++  K   +  +    E  P V  T          E  P P K +K L T +P K     
Sbjct: 997  KKETKAPAAEKLEPKAEQAPTVKRT--------ETEKKPPPIKDSKSL-TAEPQKA---- 1043

Query: 452  AKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPI 511
                PT L K P P +   L K  +++ S      PP        +  +       P P 
Sbjct: 1044 --VLPTKLEKSPKPESTCPLCKTELNIGS----KDPPNFNTCTECKNQVCNLCGFNPTPH 1097

Query: 512  AD-------AKAPEKRASPSKPA---SAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSP 561
                          +RA   +       P + SG K++     T +++   +  P  +  
Sbjct: 1098 LTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVK-- 1155

Query: 562  STLLPKKPTAIKTEGKPAEVKK----MTAKSVPADLSRPKSTSTSSMK--KTTTLSGTAP 615
              L+ K+   +KTE +   ++K    ++ + +P  ++  +    S ++  K + L    P
Sbjct: 1156 --LVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKP 1213

Query: 616  AAGVVPSRVKATPMPSR---PSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRS 672
                +P   K  P   +       P +++K  + +     P        TSAP       
Sbjct: 1214 ----LPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPE-----AKTSAP------- 1257

Query: 673  KVGSTENIKHQPGGGRVQIQNKKVD 697
                 E  KH     +VQI  +K++
Sbjct: 1258 -----EEQKHDLLKSQVQIAEEKLE 1277



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 41/162 (25%), Positives = 64/162 (39%), Gaps = 13/162 (8%)

Query: 454  TQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSIL-PSKDVKP---- 508
            T P    K+P P  IG  +         L P+ PPK P V  +  S L P K ++     
Sbjct: 3584 TSPPKDKKRPTPLEIGYSSHLRADSTVQLAPS-PPKSPKVLYSPISPLSPGKALESAFVP 3642

Query: 509  --KPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSP----S 562
              KP+ D  +P+K   P      PAS   +K  Q  + +       +   SSR+P     
Sbjct: 3643 YEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQR-SMSDPKPLSPTADESSRAPFQYTE 3701

Query: 563  TLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSM 604
                K    + + G   +VK+      P ++S    ++ S+M
Sbjct: 3702 GYTTKGSQTMTSSGAQKKVKRTLPNPPPEEISTGTQSTFSTM 3743



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 93/442 (21%), Positives = 167/442 (37%), Gaps = 82/442 (18%)

Query: 334  KDKILETPQKMTEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLP--KSTIQE 391
            KDK     +K     E K   E +K  +S   +P+    +PT       LLP  K++  E
Sbjct: 1202 KDKASALQEKKPLPEEKKLIPEEEKI-RSEEKKPLLEEKKPTPED--KKLLPEAKTSAPE 1258

Query: 392  QERHKQLKSA---------GIARP---EEGR-PVVSGTGNDITTPPNKELPPSPEKKTK- 437
            +++H  LKS          G   P   +EG+ P     G    TP  + LP   +K TK 
Sbjct: 1259 EQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTP--QSLPKEDDKTTKT 1316

Query: 438  ------PLATTQPAKTSTSKAKTQP---------TSLPKQPAPTTIGGLNKKPMSLASGL 482
                  P  T +P +    K KT+          +  PK P   +  G +   +S + G 
Sbjct: 1317 IKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGE 1376

Query: 483  VPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTV 542
            +P+  P               KD+      D+ + E  +SPS P+      S   +  ++
Sbjct: 1377 IPSLIP------------TDEKDILKGLKKDSFSQE--SSPSSPSDLAKLES---TVLSI 1419

Query: 543  AKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTS 602
             +   +            P  + P++P       K  E  +  ++++   +S  +   + 
Sbjct: 1420 LEAQASTLADEKSEKKTQPHEVSPEQP-------KDQEKTQSLSETLEITISEEEIKESQ 1472

Query: 603  SMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNT 662
              +K T    +      +PS             + F+D   T  +P  +    S  + N+
Sbjct: 1473 EERKDTFKKDSQQD---IPS------SKDHKEKSEFVDDITTRREPYDSVEESSE-SENS 1522

Query: 663  SAPDLKNVRSKVGSTENIKHQ----PGGGRVQ--IQNKKVDISKVSSKCGSKAN--IKHK 714
              P  K  R+ VGS+ + +++     G G  +  I+ + +++S      GS+ +  I+++
Sbjct: 1523 PVPQRKR-RTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQ 1581

Query: 715  PGGGDVKIESQKLNFKEKAQAK 736
                    ESQK   KE+ + K
Sbjct: 1582 LKEISSSTESQK---KEETKGK 1600


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 76/275 (27%), Positives = 98/275 (35%), Gaps = 31/275 (11%)

Query: 417 GNDITTPPNKELPPSPEKKTKPLATT--------QPAKTSTSKAKTQPTSLPKQPAPTTI 468
           G D+   P+    P P+ KT P+ TT        QP +TS  K       L K P P   
Sbjct: 647 GGDLAPVPSS---PQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKP 703

Query: 469 GGLNKKPM------------SLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKA 516
             L K+P               A  L   APPK P+V S +    P  D KPK     K 
Sbjct: 704 PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKA-PVADDKPKQPKMVKP 762

Query: 517 PEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEG 576
                S S   + P   S    +Q   KTT      S  PS   P T     P   K   
Sbjct: 763 TTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP 822

Query: 577 KPAEVKKMTAKSVPADLSRPKS-----TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPS 631
           +PA   K+ +   P+  S+ +            KK  T     P A  +P +   TP   
Sbjct: 823 RPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP-KGSPTPPGP 881

Query: 632 RPSTTPFIDKKPTSAKPSSTTPRLS-RLATNTSAP 665
           RP+    +     S KP   + R S  L + T AP
Sbjct: 882 RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAP 916



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 88/345 (25%), Positives = 129/345 (37%), Gaps = 44/345 (12%)

Query: 346 EKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLP--KSTIQEQERHKQLKSAGI 403
           EK +S+ PG GK         P++G   PT+    TP     K  +Q      Q K A I
Sbjct: 245 EKIKSQPPGTGK---------PIQG---PTQ----TPQTDHAKLPLQRDASRPQTKQADI 288

Query: 404 ARPEEGRPVVSGTGNDITTPPNKELPPSPE---KKTKPLATTQPAKTS--TSKAKTQPTS 458
            R E  +P +          P    PP+ +   +K++P     PA+ S  T     QP +
Sbjct: 289 VRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGT 348

Query: 459 L--PKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKA 516
           +  P QP  TT     K P   A  L PA PP +   +    S  P      +P    K 
Sbjct: 349 VKPPVQPPGTT-----KPP---AQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKT 400

Query: 517 PEKRASPSKPASA------PASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPT 570
           P ++  P+KP +       P ++     +   A   T   V   GP         P K +
Sbjct: 401 PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTS 460

Query: 571 AIKT-EGKPAEVKKMTAKSVPADL--SRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKAT 627
           A +T   KP       AK  P     ++P      S K  +   G+       P   K  
Sbjct: 461 AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAK-- 518

Query: 628 PMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRS 672
           P P +P +T    ++P SAKPS+  P  ++ +   S   +    S
Sbjct: 519 PSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGS 563



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 180/809 (22%), Positives = 279/809 (34%), Gaps = 113/809 (13%)

Query: 30  SELINKSSPLEVL-ESAACEKLPTPTPQVVKEGDSFPDTLAKNG-QEIAPAQISKSLMV- 86
           S ++NK +P +++ +S A ++  T   +VV++    P+ + K   Q+  P  I K     
Sbjct: 167 SSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPG 226

Query: 87  -DNYTKDGVPGQERPKGPSAVVPSTSTGGVALPITTAIETVNIHGDHS-LKNKAELADSM 144
            D   +DG P     + P  +   +   G   PI    +T     DH+ L  + + +   
Sbjct: 227 RDPLQQDGTPKSISSQQPEKI--KSQPPGTGKPIQGPTQTPQT--DHAKLPLQRDASRPQ 282

Query: 145 KNEAGIDEGHVIGESESVHSGASKHSVEKVTELAKGHLLPGVPVEDQSLPGEARALEGYA 204
             +A I  G      ESV       S   + +   G      P  ++S PG A+      
Sbjct: 283 TKQADIVRG------ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP----- 331

Query: 205 DRGNFPAHPVNEEKETKE--GSVA--VQIPDLLEDKAQKLSFCEDQNAQDRNSKGSDSLN 260
                PA P    K   +  G+V   VQ P   +  AQ L   +    Q  + K S    
Sbjct: 332 -----PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE-- 384

Query: 261 KKVDLTLLSPKSENDKLKEISLACKITELESVSLPTPEIQSDFLHSKVEAP-PSEVADTL 319
           +     L  P        +     K    + V  P P  Q   L S  +AP P++     
Sbjct: 385 QPGPKALAQPPGVGKTPAQQPGPAK-PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP--- 440

Query: 320 VIMTASKGVRLPEPKDKILETPQKMTEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRG 379
                   V+ P P     + P +     ++     G  +  S++  P K   +      
Sbjct: 441 --------VQQPGPG----KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK 488

Query: 380 LTPLLPKSTIQEQERHKQLK----SAGIARPEEGRPVVSGTGNDITTPPNKELP----PS 431
             P  P S     ++    K      G A+P   +P   G+    +  P    P    PS
Sbjct: 489 PPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQP---GSTKPPSQQPGSAKPSAQQPS 545

Query: 432 PEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKK--PMSLASGLVPAAPPK 489
           P K +   +T   ++T + K    PT  P    P +  GL K   P+   + L+   P K
Sbjct: 546 PAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPS-QGLPKTICPLCNTTELLLHVPEK 604

Query: 490 RP--AVASARPSILPSKDVKPKP-IADAK------APEKRASPSKPASAPASRSGSKSTQ 540
                    + ++       P P + + K         KRA     A  P+S      T 
Sbjct: 605 ANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT- 663

Query: 541 TVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE-GKPAEVKKMTAKSVPADLSRPKST 599
             A  TT +AV+ + P  +  S   PKK  A K +  K  E KK         L    S 
Sbjct: 664 --APVTTTSAVSKSSPQPQQTS---PKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718

Query: 600 STSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLA 659
                 +  +LS  AP         K   +PS     P  D KP   K    T  L   +
Sbjct: 719 KAKQPPEADSLSKPAPP--------KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSS 770

Query: 660 TNTSAPDLKNVRSKVGS-----------TENIK----HQPGGGRVQ-IQNKKVDISKVSS 703
           + T+ PD+ +  SKV S           T++ K      P G +V    +K +      S
Sbjct: 771 SATTKPDIPS--SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDS 828

Query: 704 KCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPL 763
           K  S      +  G       QK    +KAQ K+    +   +P          GS  P 
Sbjct: 829 KIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK---------GSPTPP 879

Query: 764 CPGPPAGEEPAISEAAPEAGAPTSASGLN 792
            P P AG+     + +P+    +    LN
Sbjct: 880 GPRPTAGQTVPTPQQSPKPQEQSRRFSLN 908



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 114/504 (22%), Positives = 169/504 (33%), Gaps = 106/504 (21%)

Query: 250  DRNSKGSDSLNKKVDLTLLSPKSENDKLKEISLACKIT-------ELESVSLPTPEIQSD 302
            D  +K  DS  +++  +   P S  D  +EIS++   T         + + +   ++ S 
Sbjct: 2215 DMITKFEDS--EEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASS 2272

Query: 303  FLHSKVEAPPSEVADTLV--IMTASKGVRLPEPKDK----ILETPQKMTEKSESKTPGEG 356
             + S V  P   VADT+   ++ + K       K+     ILE  +   +K E +     
Sbjct: 2273 IIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEA---- 2328

Query: 357  KKEDKSRMAE------PMKGYMRPTKSR-GLTPLLPKSTIQEQERHKQLKSAG---IARP 406
             +  KS ++E      P      P K +   T      T  +++   QL S      + P
Sbjct: 2329 -ERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLP 2387

Query: 407  EEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPT 466
             + RP    +  DI+  P    PP P     P     P           P   P  P PT
Sbjct: 2388 AKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPP-----------PLPPPTSPKPT 2436

Query: 467  TIGGLNKKPMSLASGLVPAAP-------------------PKRPAVASARPSILPSKDVK 507
                L KK +++AS +  A P                   P      +A P + P    K
Sbjct: 2437 I---LPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPP----K 2489

Query: 508  PKPIADAKAPEKRASPSKPASAP------ASRSGSKSTQTVAKTTTAAAVAS------TG 555
            P  I        R  PSKP  AP         +  K T    K T  +  +S      T 
Sbjct: 2490 PSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTS 2549

Query: 556  PSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADL-SRPKSTSTSSMKKTTT----- 609
               + PS   P  P + K+   P   K +T   V   L S P + + SS  +  T     
Sbjct: 2550 ADYKLPSPTSPLSPHSNKS--SPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLG 2607

Query: 610  -----LSGTAPAAGVVPSRVKATPMPSRP-------------STTPFIDKKPTSAKPSST 651
                 L    P   VVP  V A  +P                S TP        A P+S 
Sbjct: 2608 SPSKDLVSVEPVFSVVPP-VTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSV 2666

Query: 652  TPRLSRLATNTSAPDLKNVRSKVG 675
            T  L+   + T     ++    VG
Sbjct: 2667 TQFLTTEVSKTEVSATRSTAPSVG 2690



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 140/685 (20%), Positives = 231/685 (33%), Gaps = 112/685 (16%)

Query: 63   SFPDTLAKNGQEIAPAQISKSLMVDNYT---KDGVPGQERPKGPSAVVPSTSTGGVALPI 119
            S P    K       + +SKS      T   KD  P Q+  K P    P           
Sbjct: 655  SSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPP--------- 705

Query: 120  TTAIETVNIHGDHSLKNKAEL-ADSMKNEAGIDEGHVIGESESVHSGASKHS----VEKV 174
               ++   +HG  S K K    ADS+   A   E  V  E +       K      V+  
Sbjct: 706  --LVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPT 763

Query: 175  TELAKGHLL---PGVPVEDQSLPGEARALEGYADRGNFPAH--PVNEEKETKEGSVAVQI 229
            T+L         P +P        E +           P+   P   EK +   S A+  
Sbjct: 764  TDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPR 823

Query: 230  PDLLEDKAQKLSFCEDQNAQDRNSKGSDSLNKKVD----LTLLSPKSENDKLKEISLAC- 284
            P        K+      +++ +  K  D + KK +     T +SPK +   + + S    
Sbjct: 824  PA----SDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP 879

Query: 285  --KITELESVSLPT----PEIQSDF----LHSKVEAP---PSEVADTLVIMTASKGVRLP 331
              + T  ++V  P     P+ QS      L S  +AP   P+   +T+       G  + 
Sbjct: 880  GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIF 939

Query: 332  EPKDKILETPQKMTEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQE 391
                 ++ T  +    S+S  PG   K+  +    P      P KS G  P  P  +I  
Sbjct: 940  SQASNLISTAGQPGPHSQSG-PGAPMKQAPAPSQPPTS--QGPPKSTGQAPPAPAKSIPV 996

Query: 392  QERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSK 451
            ++  K   +  +    E  P V  T          E  P P K +K L T +P K     
Sbjct: 997  KKETKAPAAEKLEPKAEQAPTVKRT--------ETEKKPPPIKDSKSL-TAEPQKA---- 1043

Query: 452  AKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPI 511
                PT L K P P +   L K  +++ S      PP        +  +       P P 
Sbjct: 1044 --VLPTKLEKSPKPESTCPLCKTELNIGS----KDPPNFNTCTECKNQVCNLCGFNPTPH 1097

Query: 512  AD-------AKAPEKRASPSKPA---SAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSP 561
                          +RA   +       P + SG K++     T +++   +  P  +  
Sbjct: 1098 LTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVK-- 1155

Query: 562  STLLPKKPTAIKTEGKPAEVKK----MTAKSVPADLSRPKSTSTSSMK--KTTTLSGTAP 615
              L+ K+   +KTE +   ++K    ++ + +P  ++  +    S ++  K + L    P
Sbjct: 1156 --LVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKP 1213

Query: 616  AAGVVPSRVKATPMPSR---PSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRS 672
                +P   K  P   +       P +++K  + +     P        TSAP       
Sbjct: 1214 ----LPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPE-----AKTSAP------- 1257

Query: 673  KVGSTENIKHQPGGGRVQIQNKKVD 697
                 E  KH     +VQI  +K++
Sbjct: 1258 -----EEQKHDLLKSQVQIAEEKLE 1277



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 41/162 (25%), Positives = 64/162 (39%), Gaps = 13/162 (8%)

Query: 454  TQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSIL-PSKDVKP---- 508
            T P    K+P P  IG  +         L P+ PPK P V  +  S L P K ++     
Sbjct: 3584 TSPPKDKKRPTPLEIGYSSHLRADSTVQLAPS-PPKSPKVLYSPISPLSPGKALESAFVP 3642

Query: 509  --KPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSP----S 562
              KP+ D  +P+K   P      PAS   +K  Q  + +       +   SSR+P     
Sbjct: 3643 YEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQR-SMSDPKPLSPTADESSRAPFQYTE 3701

Query: 563  TLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSM 604
                K    + + G   +VK+      P ++S    ++ S+M
Sbjct: 3702 GYTTKGSQTMTSSGAQKKVKRTLPNPPPEEISTGTQSTFSTM 3743



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 93/442 (21%), Positives = 167/442 (37%), Gaps = 82/442 (18%)

Query: 334  KDKILETPQKMTEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLP--KSTIQE 391
            KDK     +K     E K   E +K  +S   +P+    +PT       LLP  K++  E
Sbjct: 1202 KDKASALQEKKPLPEEKKLIPEEEKI-RSEEKKPLLEEKKPTPED--KKLLPEAKTSAPE 1258

Query: 392  QERHKQLKSA---------GIARP---EEGR-PVVSGTGNDITTPPNKELPPSPEKKTK- 437
            +++H  LKS          G   P   +EG+ P     G    TP  + LP   +K TK 
Sbjct: 1259 EQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTP--QSLPKEDDKTTKT 1316

Query: 438  ------PLATTQPAKTSTSKAKTQP---------TSLPKQPAPTTIGGLNKKPMSLASGL 482
                  P  T +P +    K KT+          +  PK P   +  G +   +S + G 
Sbjct: 1317 IKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGE 1376

Query: 483  VPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTV 542
            +P+  P               KD+      D+ + E  +SPS P+      S   +  ++
Sbjct: 1377 IPSLIP------------TDEKDILKGLKKDSFSQE--SSPSSPSDLAKLES---TVLSI 1419

Query: 543  AKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTS 602
             +   +            P  + P++P       K  E  +  ++++   +S  +   + 
Sbjct: 1420 LEAQASTLADEKSEKKTQPHEVSPEQP-------KDQEKTQSLSETLEITISEEEIKESQ 1472

Query: 603  SMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNT 662
              +K T    +      +PS             + F+D   T  +P  +    S  + N+
Sbjct: 1473 EERKDTFKKDSQQD---IPS------SKDHKEKSEFVDDITTRREPYDSVEESSE-SENS 1522

Query: 663  SAPDLKNVRSKVGSTENIKHQ----PGGGRVQ--IQNKKVDISKVSSKCGSKAN--IKHK 714
              P  K  R+ VGS+ + +++     G G  +  I+ + +++S      GS+ +  I+++
Sbjct: 1523 PVPQRKR-RTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQ 1581

Query: 715  PGGGDVKIESQKLNFKEKAQAK 736
                    ESQK   KE+ + K
Sbjct: 1582 LKEISSSTESQK---KEETKGK 1600



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 17/107 (15%)

Query: 495  SARPSILPSKD--VKPKPIADAKAPEKRASPSKPASAPA-----------SRSGSKSTQT 541
            S +PS++ S+   + P P  D + P    S S P S+ +           SRS SK++ T
Sbjct: 4846 SPKPSVIKSRSHGIFPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVT 4905

Query: 542  VAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKS 588
                  A A  +   ++     + P KP       +PAE    T  S
Sbjct: 4906 QTHLEDAGAAIAAAEAAVQQLRIQPTKP----PNHRPAESSVSTGSS 4948


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 108/493 (21%), Positives = 171/493 (34%), Gaps = 37/493 (7%)

Query: 293 SLPT--PEIQSDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEKSES 350
           SLP   P+I S   H KV++         V+  + K   + E + +  +  +++TE+ E 
Sbjct: 421 SLPEGLPKIPSVSTHIKVKSEEK----IKVVEKSEKETVIVEEQTEETQVTEEVTEEEEK 476

Query: 351 KTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGR 410
           +   E  KE++    E  +G    TKS    P   ++   E+E    +K    +  E   
Sbjct: 477 EAKEEEGKEEEGGEEEEAEGGEEETKS----PPAEEAASPEKEAKSPVKEEAKSPAEAKS 532

Query: 411 PVVSGTGN--DITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTI 468
           P      +  ++ +P   + P   E K+ P A +   + + S A+ +     K PA    
Sbjct: 533 PEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA 592

Query: 469 GGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPAS 528
               K P    S     +P K  A + A     P K+    P A+ K+PEK  SP+K  +
Sbjct: 593 ----KSPAEAKSPEKAKSPVKEEAKSPAEAK-SPVKEEAKSP-AEVKSPEKAKSPTKEEA 646

Query: 529 APASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKS 588
              S   +KS +     +   A +     ++SP     K  + +K E K  E  K   K 
Sbjct: 647 --KSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPE----KAKSPVKAEAKSPEKAKSPVKE 700

Query: 589 VPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKP 648
                 + KS      K               P + K +P+           K P  AK 
Sbjct: 701 EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAK-SPVKEEA-------KSPEKAKS 752

Query: 649 SSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSK 708
                 L   +     P  +  RS           P    V+   K     K  +K   K
Sbjct: 753 PEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEK 812

Query: 709 ANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLP----AGGAVKTEGGGSEAPLC 764
              K +     VK E +    K K   K    +     P       + K E    EAP  
Sbjct: 813 EIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPK- 871

Query: 765 PGPPAGEEPAISE 777
           P     +EPA+ +
Sbjct: 872 PKVEEKKEPAVEK 884



 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 115/535 (21%), Positives = 184/535 (34%), Gaps = 65/535 (12%)

Query: 135  KNKAELADSMKNEAGIDEGHVIGESESVHSGAS------KHSVEKVTELAKGHLLPGVPV 188
            + +A+  +  + E G +E    GE E+    A       K +   V E AK       P 
Sbjct: 475  EKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPE 534

Query: 189  EDQSL-PGEARALEGYA----DRGNFPAHPVNEEKETKEGSVAVQIPDLLEDKAQKLSFC 243
            ++++  P E ++ E       +    P    + EKE  +    V+ P+  +  A+     
Sbjct: 535  KEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAK----- 589

Query: 244  EDQNAQDRNSKGSDSLNKKVDLTLLSPKSENDKLKEISLA-CKITELESVSLPTPEI--- 299
             ++      +K  +     V     SP      +KE + +  ++   E    PT E    
Sbjct: 590  -EEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKS 648

Query: 300  -QSDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTE--KSESKTPGEG 356
             +      K EA   E A + V   A    +   P     ++P+K     K E+K+P + 
Sbjct: 649  PEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKA 708

Query: 357  KKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERH-------KQLKSAGIARPEEG 409
            K   K     P K    P K    TP   KS ++E+ +        ++ K+  +  PE  
Sbjct: 709  KSPVKEEAKSPEKA-KSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAK 767

Query: 410  RPVVSGTGN------DITTPPNKELPPSPEKKTKPLATTQPA------------------ 445
             P      +      +    P KE   SPEK   PL     A                  
Sbjct: 768  TPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEE 827

Query: 446  -KTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAP------PKRPAVASARP 498
             K    K K  P    ++ AP T     KK           AP       K PAV   + 
Sbjct: 828  EKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKE 887

Query: 499  SILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSS 558
            S + +K  + +       PEK A P+K      ++   K+     +   A A   + P+ 
Sbjct: 888  SKVEAKKEEAEDKKKVPTPEKEA-PAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAE 946

Query: 559  RSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGT 613
            +  +    KK T  +   KP E  K  AK+   D +  K  S    +K    S T
Sbjct: 947  KKEAA-PEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSST 1000



 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 108/482 (22%), Positives = 169/482 (35%), Gaps = 59/482 (12%)

Query: 330 LPEPKDKILETPQKMTEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTI 389
           LPE   KI      +  KSE K     K E ++ + E      + T+             
Sbjct: 422 LPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEE------------ 469

Query: 390 QEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTST 449
             +E  K+ K       E G    +  G + T  P  E   SPEK+ K  +  +    S 
Sbjct: 470 VTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAK--SPVKEEAKSP 527

Query: 450 SKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPK 509
           ++AK+      K PA        K P    S       P +    S   +  P K+    
Sbjct: 528 AEAKSPEKEEAKSPAEV------KSPEKAKS-------PAKEEAKSPPEAKSPEKEEAKS 574

Query: 510 PIADAKAPEKRASPSKP-ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKK 568
           P A+ K+PEK  SP+K  A +PA     +  ++  K       A +   ++SP     K 
Sbjct: 575 P-AEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEE-----AKSPAEAKSPVKEEAKS 628

Query: 569 PTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATP 628
           P  +K+  K     K  AKS     S  K  + S  K  + +   A +     S VKA  
Sbjct: 629 PAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEA 688

Query: 629 MPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQ---PG 685
                + +P  ++  +  K  S     ++      +P  +  ++   +   +K +   P 
Sbjct: 689 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPE 748

Query: 686 GGRVQIQNKKVDISKVSSKCGSKANIK----------HKPGGGDVKI-ESQKLNFKEKAQ 734
             +   + K +D+    +K  +K   +            P   +VK  E  K   KE A+
Sbjct: 749 KAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAK 808

Query: 735 A---------KVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAIS--EAAPEAG 783
           A         +V S       P    VK     +E    P  P  EE   S  E AP+  
Sbjct: 809 APEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKE 868

Query: 784 AP 785
           AP
Sbjct: 869 AP 870



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 114/507 (22%), Positives = 175/507 (34%), Gaps = 87/507 (17%)

Query: 35   KSSPLEVLESAACEKLPTPTPQVVKEGDSFPDTLAKNGQEIA--PAQISKSLMVDNYTKD 92
            KS   E  +S A  K P      VKE    P       +E A  PA++       + TK+
Sbjct: 585  KSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKE 644

Query: 93   GVPGQERPKGPSAVVPSTSTGGVALPITTAIETVNIHGDHSLKNKAELADSMKNEAGIDE 152
                 E+ K P     + S      P+    ++           KAE     K ++ + E
Sbjct: 645  EAKSPEKAKSPEKE-EAKSPEKAKSPVKAEAKSPE---KAKSPVKAEAKSPEKAKSPVKE 700

Query: 153  GHVIGESESVHSGASKHSVEKVTELAKGHLLPGVPVEDQS-LPGEARALEGYADRGNFPA 211
                 E++S     S      V E AK       PV++++  P +A++            
Sbjct: 701  -----EAKSPEKAKSP-----VKEEAKSPEKAKSPVKEEAKTPEKAKS------------ 738

Query: 212  HPVNEEKETKEGSVAVQIPDLLEDKAQKLSFCEDQNAQDRNSKGSDSLNKKVDLTLLSPK 271
             PV EE ++ E + + +    L+ K+ +      + A+    K  +     V   + SP+
Sbjct: 739  -PVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPE 797

Query: 272  SENDKLKEISLACK--ITELESVSLPTPEIQSDFLHSKVEAPPSEVADTLVIMTASKGVR 329
                 LKE + A +  I + E V  P  E          E  P EV              
Sbjct: 798  KAKSPLKEDAKAPEKEIPKKEEVKSPVKE----------EEKPQEV-------------- 833

Query: 330  LPEPKDKILETPQKMTEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTI 389
                  K+ E P+K  E+    TP   +K+D  +   P K   +P       P + K   
Sbjct: 834  ------KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKE 887

Query: 390  QEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKK--TKPLATTQPAKT 447
             + E  K+         E+ + V +         P KE P   E K   KP   T+ AK 
Sbjct: 888  SKVEAKKE-------EAEDKKKVPT---------PEKEAPAKVEVKEDAKPKEKTEVAKK 931

Query: 448  STSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVK 507
                AK +    P +PA        KK         P   PK  A A      L  +  K
Sbjct: 932  EPDDAKAKE---PSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSK 988

Query: 508  PKPIADAKAPEKRASPSKPASAPASRS 534
            PK    A+  EK +S  +  S P  ++
Sbjct: 989  PK----AEKAEKSSSTDQKDSKPPEKA 1011



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 101/451 (22%), Positives = 163/451 (36%), Gaps = 48/451 (10%)

Query: 160  ESVHSGASKHSVEK----VTELAKGHLLPGVPVEDQSL-PGEARALEGYA----DRGNFP 210
            E   S A   S EK    V E AK       PV++++  P E ++ E       +    P
Sbjct: 590  EEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSP 649

Query: 211  AHPVNEEKETKEGSVAVQIPDLLEDKAQKLSFCEDQNAQDRNSKGSDSLNKKVDLTLLSP 270
                + EKE  +     + P   E K+ + +    ++     +K  +     V     SP
Sbjct: 650  EKAKSPEKEEAKSPEKAKSPVKAEAKSPEKA----KSPVKAEAKSPEKAKSPVKEEAKSP 705

Query: 271  KSENDKLKEISLAC-KITELESVSLPTPEIQSDFLHSKVEAPPS----EVADTLVIMTAS 325
            +     +KE + +  K          TPE     +  + ++P      E A TL      
Sbjct: 706  EKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTL------ 759

Query: 326  KGVRLPEPKDKILETPQKMTEKSESKTPGEGKKEDKS--RMAEPMKGYMRPTKSRGLTPL 383
              V+ PE K    E  +   +K   K     K+E KS  +   P+K   +  +       
Sbjct: 760  -DVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKE 818

Query: 384  LPKSTIQEQERHKQLKSAGIARP--EEGRPVVSGTGNDITTP----PNKELP-PSPEKKT 436
              KS ++E+E+ +++K     +   EE  P    T     +     P KE P P  E+K 
Sbjct: 819  EVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKK 878

Query: 437  KPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASA 496
            +P A  +P ++     K +     K P P       K+  +       A P ++  VA  
Sbjct: 879  EP-AVEKPKESKVEAKKEEAEDKKKVPTP------EKEAPAKVEVKEDAKPKEKTEVAKK 931

Query: 497  RPSIL----PSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK-STQTVAKTTTAAAV 551
             P       PSK  + K  A  K   K     KP   P + + +K   +T++K  +    
Sbjct: 932  EPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKA 991

Query: 552  ASTGPSSRSPSTLLPKKPTAIKTEGKPAEVK 582
                 SS +       KP    TE K A+ K
Sbjct: 992  EKAEKSSSTDQK--DSKPPEKATEDKAAKGK 1020


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 72/315 (22%), Positives = 127/315 (40%), Gaps = 40/315 (12%)

Query: 382  PLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELP----PSPEKKTK 437
            P+ P +T+   E      +  ++ PEE     +     + TP     P    P+PE+ T 
Sbjct: 974  PVTPATTVHAPEE-PDTAAVRVSTPEEPASPAAA----VPTPEEPTSPAAAVPTPEEPTS 1028

Query: 438  PLATTQPAKTSTSKAKTQPTSLPKQP-APTTIGGLNKKPMSLASGLVPAAPPKRPAVASA 496
            P A   P +  TS A   PT  P++P +P       ++P S A+ +     P  PA A  
Sbjct: 1029 PAAAVPPPEEPTSPAAAVPT--PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1086

Query: 497  RP-------SILPSKDVKPKPIADAKAPEKRASPS-------KPASAPAS-------RSG 535
             P       + +P+ +    P A    PE+ ASP+       +PAS  A+          
Sbjct: 1087 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFP 1146

Query: 536  SKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSR 595
            + +  T  ++ +AA    T   S SP+  +   PT  ++    A V  +   + PA    
Sbjct: 1147 APAVPTPEESASAAVAVPTPEESASPAAAV---PTPAESASFAAVVATLEEPTSPAASVP 1203

Query: 596  PKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST----TPFIDKKPTSAKPSST 651
              +   +++++ T+ + + P +    S   A   P  P++     P +++  +SA    T
Sbjct: 1204 TPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLT 1263

Query: 652  TPRLSRLATNTSAPD 666
               LS  A +   P+
Sbjct: 1264 PEELSSPAASVPTPE 1278



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 56/246 (22%), Positives = 88/246 (35%), Gaps = 23/246 (9%)

Query: 431  SPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKR 490
            +PE+ T P  T    + + + A     S P++ AP     + ++ MS  +G  P      
Sbjct: 903  APERATVPAVTVSVPEGTAAVAAV---SSPEETAPAVAAAITQEGMSAVAGFSPEWAALA 959

Query: 491  PAVASARPSILPSKDVKPKPIADA-----------KAPEKRASPSKPASAPAS-RSGSKS 538
              V        P   V P     A             PE+ ASP+     P    S + +
Sbjct: 960  ITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAA 1019

Query: 539  TQTVAKTTTAAAVASTGPSSRSPSTLL--PKKPTAIKTEGKPAEVKKMTAKSVPADLSRP 596
              T  + T+ AA         SP+  +  P++PT+        E     A +VP     P
Sbjct: 1020 VPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT----P 1075

Query: 597  KSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLS 656
            +  ++ +    T    T+PAA V       +P  + P  TP     P +A P+   P   
Sbjct: 1076 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP--TPEEPASPAAAVPTPEEPASP 1133

Query: 657  RLATNT 662
              A  T
Sbjct: 1134 AAAVPT 1139



 Score = 38.1 bits (87), Expect = 0.033
 Identities = 57/253 (22%), Positives = 96/253 (37%), Gaps = 21/253 (8%)

Query: 413  VSGTGNDITTPPNKELPPSPEK--KTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGG 470
            V+  GN  T P  +E  P  ++  +T  + T + A  +   +  + TS+   PAP     
Sbjct: 814  VTKAGN--TEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAP----- 866

Query: 471  LNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAP 530
               +  ++ + LVP  P +   VAS     + S + +    A   APE+   P+   S P
Sbjct: 867  ---EGTAVVAALVPF-PHEDILVAS-----IVSLEEEDVTAAAVSAPERATVPAVTVSVP 917

Query: 531  ASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVP 590
               +   +  +  +T  A A A T     + +   P+      T     E         P
Sbjct: 918  EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTP 977

Query: 591  A-DLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPS 649
            A  +  P+   T++++ +T     +PAA V       +P  + P  TP     P +A P 
Sbjct: 978  ATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVP--TPEEPTSPAAAVPP 1035

Query: 650  STTPRLSRLATNT 662
               P     A  T
Sbjct: 1036 PEEPTSPAAAVPT 1048


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 90/390 (23%), Positives = 155/390 (39%), Gaps = 52/390 (13%)

Query: 311  PPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEKSESKTPGEGKKEDKSRMAEPMKG 370
            P +  A+     T ++G+ +P        TP      SE KTP +      + +A     
Sbjct: 1426 PGTTSAEATSSPTTAEGISIPT------STP------SEGKTPLKSIPVSNTPVANSEAS 1473

Query: 371  YMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPP 430
             +  T     +P++  + +       +  S  I+ P EG   ++      TT  + E+  
Sbjct: 1474 TLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEI-- 1531

Query: 431  SPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVP--AAPP 488
                    L+TT PA TST        S     +PTT  G + +  + + G  P  + P 
Sbjct: 1532 ------NSLSTT-PAVTSTPVTTYSQAS----SSPTTADGTSMQTSTYSEGSTPLTSLPV 1580

Query: 489  KRPAVASARPSILPSK--DVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTT 546
                V S+  + L +   D K +  A  +A     +     +      GS    ++  +T
Sbjct: 1581 STMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVST 1640

Query: 547  T------AAAVASTGPSSRSP--------STLLPKK----PTAIKTEGKPAEVKKMTAKS 588
            T      A+ +++T   S SP        S+  P +    PT+  TEG+   +  +T ++
Sbjct: 1641 TPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGR-TPLTSITVRT 1699

Query: 589  VPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKP 648
             P   S   + ST+ +  +T ++ T+  A   P+  + T MP+   +TP     P ++ P
Sbjct: 1700 TPVASSAISTLSTTPVDNSTPVT-TSTEARSSPTTSEGTSMPN---STPSEGTTPLTSIP 1755

Query: 649  SSTTPRLSRLATNTSAPDLKNVRSKVGSTE 678
             STTP LS  A+  SA  +        STE
Sbjct: 1756 VSTTPVLSSEASTLSATPIDTSTPVTTSTE 1785



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 99/409 (24%), Positives = 152/409 (37%), Gaps = 47/409 (11%)

Query: 287  TELESVSLPTPEIQSDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETP-QKMT 345
            T  E  S+PT    S +   +       V+ TLV  +A   +    P D    TP    T
Sbjct: 848  TPAEGTSMPT----STYSEGRTPLTSMPVSTTLVATSAISTLSTT-PVDT--STPVTNST 900

Query: 346  EKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPL--LPKSTIQEQERHKQLKSAGI 403
            E   S T  EG     S            T   G TPL  +P ST        +  SA  
Sbjct: 901  EARSSPTTSEGTSMPTS------------TPGEGSTPLTSMPDSTTPVVSSEARTLSA-- 946

Query: 404  ARPEEGRPVVSGTG--NDITTPPNKELPPS-PEKKTKPLATTQPAKT--STSKAKTQPTS 458
               +   PV + T   +  TT     +P S P + T PL +T  + T  + S+A T  T+
Sbjct: 947  TPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTT 1006

Query: 459  LPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPE 518
                  P T       P   A G   + P   P+  S   + +P   V    +A ++   
Sbjct: 1007 PVDSNTPLTTSTEASSPPPTAEGT--SMPTSTPSEGSTPLTRMP---VSTTMVASSETST 1061

Query: 519  KRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP 578
               +P+  ++   + S + S+ T A  T+     ST     +P T +P     + +    
Sbjct: 1062 LSTTPADTSTPVTTYSQASSSSTTADGTSMPT--STYSEGSTPLTSVPVSTRLVVSS--- 1116

Query: 579  AEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPF 638
               +  T  + P D S P +TST +    TT  GT+      P     TP+ S P +T  
Sbjct: 1117 ---EASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTS--PPSEGTTPLASMPVSTTL 1171

Query: 639  IDKKPTSAKPSSTTPRLSRLATNTSA---PDLKNVRSKVGSTENIKHQP 684
            +     +   ++     +++AT+T A   P    V S   ST   +  P
Sbjct: 1172 VVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTP 1220



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 96/399 (24%), Positives = 143/399 (35%), Gaps = 57/399 (14%)

Query: 287 TELESVSLPTPEIQSDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETP-QKMT 345
           T  E  S+PT    S +           V+ TLV  + +  +    P D    TP    T
Sbjct: 612 TTAEGTSMPT----STYSERGTTITSMSVSTTLVASSEASTLSTT-PVDS--NTPVTTST 664

Query: 346 EKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIAR 405
           E + S T  EG     S            T + G TPL             +  +     
Sbjct: 665 EATSSSTTAEGTSMPTS------------TYTEGSTPLTSMPVNTTLVASSEASTLSTTP 712

Query: 406 PEEGRPVVSGT--GNDITTPPNKELPPS-PEKKTKPLATTQPAKT--STSKAKTQPTS-L 459
            +   PV + T   +  TT     +P S P + + PL +   +KT  ++S+A T  T+ L
Sbjct: 713 VDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPL 772

Query: 460 PKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEK 519
                 TT    +  P +     +P + P      S    +L S  V   P+   +A   
Sbjct: 773 DTSTHITTSTEASCSPTTTEGTSMPISTP------SEGSPLLTSIPVSITPVTSPEASTL 826

Query: 520 RASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPA 579
             +P    S   + +   S+ T A+ T+     ST    R+P T +P   T + T     
Sbjct: 827 STTPVDSNSPVTTSTEVSSSPTPAEGTSMPT--STYSEGRTPLTSMPVSTTLVATSAIS- 883

Query: 580 EVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFI 639
                T  + P D S P + ST +    TT  GT                 S P++TP  
Sbjct: 884 -----TLSTTPVDTSTPVTNSTEARSSPTTSEGT-----------------SMPTSTPGE 921

Query: 640 DKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTE 678
              P ++ P STTP +S  A   SA  +        STE
Sbjct: 922 GSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTE 960



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 99/430 (23%), Positives = 155/430 (36%), Gaps = 41/430 (9%)

Query: 285  KITELESVSLPTPEI-QSDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQK 343
            ++T  E  +L TP +  S  + +  EA  S        M+ S  + +      IL +   
Sbjct: 3705 RVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTP 3764

Query: 344  MTEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGI 403
            +T   ES TP          M    +G   PT   G T + P ST  E  R   L +  I
Sbjct: 3765 VTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTM-PMSTTSE--RSTLLTTVLI 3821

Query: 404  ARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAK-TQPTSLPKQ 462
            +      P  + T   ++TPP     P     TK  + + PA+ +T +   T   S P  
Sbjct: 3822 SPISVMSPSEAST---LSTPPGDTSTPLLTS-TKAGSFSIPAEVTTIRISITSERSTPL- 3876

Query: 463  PAPTTIGGLNKKPMSLASGLVPAAPPKRPAVA-------SARPSILPSKDVKPKPIADAK 515
               TT+      P S     + + PP   +         ++ P+I  +  +    I +  
Sbjct: 3877 ---TTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGS 3933

Query: 516  APEKRAS-PSKPASAPAS-----RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKP 569
             P      PS P ++  +      +G+ ST  +  T       S+  ++ S ST      
Sbjct: 3934 TPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTT 3993

Query: 570  TAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTT--LSGTAPAAGVVPSRVKAT 627
             A+ T      V   TA S P   SR  +TS S++  T+T   S +     V PS   + 
Sbjct: 3994 PAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSR 4053

Query: 628  PM------------PSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNV-RSKV 674
            P             P+  ST P      T+  P + T   +R   +T       V  + V
Sbjct: 4054 PSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAV 4113

Query: 675  GSTENIKHQP 684
             +   IK  P
Sbjct: 4114 PTNTTIKSNP 4123



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 97/372 (26%), Positives = 135/372 (36%), Gaps = 72/372 (19%)

Query: 345  TEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIA 404
            TE S S TP EG     S            T S G TPL              + +    
Sbjct: 3081 TEVSSSPTPAEGTSMPIS------------TYSEGSTPLTGVPVSTTPVTSSAISTLSTT 3128

Query: 405  RPEEGRPVVSGTG--NDITTPPNKELPPS-PEKKTKPLATTQPAKT--------STSKAK 453
              +   PV + T   +  TT     +P S P + + PL T  P  T        ST  A 
Sbjct: 3129 PVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPL-TYMPVSTMLVVSSEDSTLSAT 3187

Query: 454  TQPTSLP-----KQPAPTTIGGLNKKPMSLASGLVP--AAPPKRPAVASARPSILPSKDV 506
               TS P     +  + TT  G +    + + G+ P  + P     VAS+  SIL +  V
Sbjct: 3188 PVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPV 3247

Query: 507  KPK-PIADA----KAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAST------- 554
                P+  +     +P      S P S P+  S   ++  V+ TT A++  ST       
Sbjct: 3248 DSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPAD 3307

Query: 555  ---------GPSSRSPSTLLPKKPTAIKTEGKP------------AEVKKMTAKSVPADL 593
                       SS  P       PT+  +EG                 +  T  + P D 
Sbjct: 3308 TSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDT 3367

Query: 594  SRPKSTSTSSMKKTTTLSGTA-PAAGVVPSRVKATPMPSRP-STTPFIDKKPTSAKPSST 651
            S P +TST +    TT  GT+ P +   PS    TP+ S P STTP +  +  +    ST
Sbjct: 3368 STPVTTSTEASLSPTTAEGTSIPTSS--PSE-GTTPLASMPVSTTPVVSSEVNTL---ST 3421

Query: 652  TPRLSRLATNTS 663
            TP  S     TS
Sbjct: 3422 TPVDSNTLVTTS 3433



 Score = 60.1 bits (144), Expect = 8e-09
 Identities = 88/383 (22%), Positives = 137/383 (35%), Gaps = 61/383 (15%)

Query: 323  TASKGVRLPEPKDKILETP-------QKMTEKSESKTPGEGKKEDKSRMAEPMKGYMRPT 375
            T + G  +P P      TP         +   SE+ T      +  +      +G   PT
Sbjct: 1968 TTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPT 2027

Query: 376  KSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKK 435
             + G +      T    ER   L  AG+  P     VVS  GN ++T P        + K
Sbjct: 2028 TAGGTSI----QTSTPSERTTPL--AGM--PVSTTLVVSSEGNTLSTTP-------VDSK 2072

Query: 436  TKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVAS 495
            T+   +T+ + ++T++  +   S P + +P     L   P+S      P A         
Sbjct: 2073 TQVTNSTEASSSATAEGSSMTISAPSEGSPL----LTSIPLSTTPVASPEASTLSTTPVD 2128

Query: 496  ARPSILPSKDVKPKPIA------DAKAPEKRASP--SKPASAPASRSGSKSTQTVAKTTT 547
            +   ++ S +V   PI              R +P  S P S     S + ST +     T
Sbjct: 2129 SNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDT 2188

Query: 548  AAAVASTGPSSRSPSTLL-PKKPTAIKTEGKP------------AEVKKMTAKSVPADLS 594
            +  V ++  +  SP+T      PT+  +EG                 +  T  + P D S
Sbjct: 2189 STPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTS 2248

Query: 595  RPKSTSTSSMKKTTTLSGTA-PAAGVVPSRVKATPMP-----------SRPSTTPFIDKK 642
             P +TST +    TT  GT+ P + +       T +P           S  STTP     
Sbjct: 2249 TPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNT 2308

Query: 643  P--TSAKPSSTTPRLSRLATNTS 663
            P  TS + SS  P     +  TS
Sbjct: 2309 PFTTSTEASSPPPTAEGTSMPTS 2331



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 92/376 (24%), Positives = 135/376 (35%), Gaps = 58/376 (15%)

Query: 345  TEKSESKTPGEGKK---EDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSA 401
            TE S S T  EG        S ++ P+   +  T     +     ST     R     SA
Sbjct: 2904 TEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSA 2963

Query: 402  GIARPEEGRPVVSGTGNDITTPPNKELP-PSPEKKTKPLATTQPAKTSTSKAKTQP---T 457
                         GT   I+TP  +  P  S    T P+A+++ +  S + A T     T
Sbjct: 2964 ---EASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTT 3020

Query: 458  SLPKQPAPTTIGGLNKKPMSLASGLVP--AAPPKRPAVASARPSILPSKDVKPK-PIADA 514
            S     +PTT  G      + + G  P  + P     VA    S L +  V    P+  +
Sbjct: 3021 STEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTS 3080

Query: 515  KAPEKRASPSKPASAPASRSGSKST-------QTVAKTTTAAAVASTGP----------- 556
                   +P++  S P S     ST        T   T++A +  ST P           
Sbjct: 3081 TEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTST 3140

Query: 557  -SSRSPSTLL-PKKPTAIKTEGKP------------AEVKKMTAKSVPADLSRPKSTSTS 602
             +  SP+T      PT+  +EG                 +  T  + P D S P +TST 
Sbjct: 3141 EAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTE 3200

Query: 603  SMKKT----TTLSGTAPAAGVVPSR---VKATPMPSRP----STTPFIDKKP--TSAKPS 649
            +   T    T++  + P+ G+ P     V  TP+ S      STTP     P  TS + S
Sbjct: 3201 ATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEAS 3260

Query: 650  STTPRLSRLATNTSAP 665
            S+ P     +  TS P
Sbjct: 3261 SSPPTAEGTSMPTSTP 3276



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 91/395 (23%), Positives = 142/395 (35%), Gaps = 57/395 (14%)

Query: 287  TELESVSLPTPEIQSDFLHSKVEAPPSEV-ADTLVIMTASKGVRLPEPKDKILETPQKMT 345
            T  +  S+PT        +S+   P + V   T +++++        P D  +      T
Sbjct: 1084 TTADGTSMPTST------YSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTS-T 1136

Query: 346  EKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIAR 405
            E S S T  EG     S  +E          S  L      +T+       + + A    
Sbjct: 1137 EASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTE 1196

Query: 406  PEEGRPVVSGTGNDITTPPNKELP-PSPEKKTKPLATTQPAKTSTSKAKTQP---TSLPK 461
                 P    T    +TP  +  P  S   +  P+A+++ +  STS   T     TS   
Sbjct: 1197 ASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAET 1256

Query: 462  QPAPTTIGGLNKKPMSLASG--LVPAAPPKRPAVASARPSILPSKDVKPK-PIADAKAPE 518
              +PTT  G +    + + G  L+ + P     V S   S L +  V  K P+  +    
Sbjct: 1257 SSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVS 1316

Query: 519  KRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP 578
               +P++  S P S                     T    R+P T +P   T +      
Sbjct: 1317 SSPTPAEGTSMPTS---------------------TYSEGRTPLTSIPVNTTLV------ 1349

Query: 579  AEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTA-----PAAGVVPSRVKATPMPSRP 633
            A        + P D S P +TST +    TT  GT+     P+ G        TP+ S P
Sbjct: 1350 ASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEG-------TTPLTSIP 1402

Query: 634  -STTPFIDKKPT--SAKPSSTTPRLSRLATNTSAP 665
             STTP +  + +  SA P  T+   +  A  TS+P
Sbjct: 1403 VSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSP 1437



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 69/283 (24%), Positives = 106/283 (37%), Gaps = 57/283 (20%)

Query: 400  SAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSL 459
            S  I+ P EG P+++     IT   +   P +    T P+ +  P  TST +  + PT  
Sbjct: 795  SMPISTPSEGSPLLTSIPVSITPVTS---PEASTLSTTPVDSNSPVTTST-EVSSSPTPA 850

Query: 460  PKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPK-PIADAKAPE 518
                 PT+     + P++       + P     VA++  S L +  V    P+ ++    
Sbjct: 851  EGTSMPTSTYSEGRTPLT-------SMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEAR 903

Query: 519  KRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKP 578
               + S+  S P S  G  ST                     P T +P   T + +    
Sbjct: 904  SSPTTSEGTSMPTSTPGEGST---------------------PLTSMPDSTTPVVSS--- 939

Query: 579  AEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTA-----PAAGVVPSRVKATPM---- 629
               +  T  + P D S P +TST +    TT  GT+     P+ G  P  + +TP+    
Sbjct: 940  ---EARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTP--LTSTPVSHTL 994

Query: 630  -----PSRPSTTPFIDKKP--TSAKPSSTTPRLSRLATNTSAP 665
                  S  STTP     P  TS + SS  P     +  TS P
Sbjct: 995  VANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTP 1037



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 88/352 (25%), Positives = 125/352 (35%), Gaps = 51/352 (14%)

Query: 345  TEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIA 404
            TE S S  P EG     S  ++          S   T ++  S I          S  + 
Sbjct: 2137 TEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVS---TTVVASSAISTLSTTPVDTSTPVT 2193

Query: 405  RPEEGR--PVVS-GTGNDITTPPNKELP-PSPEKKTKPLATTQPAKTSTSKAKTQP---T 457
               E R  P  S GT    +TP     P  S    T P+ T++ +  S +   T     T
Sbjct: 2194 NSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTT 2253

Query: 458  SLPKQPAPTTIGGLNKKPMSLASGLVP--AAPPKRPAVASARPSILPSKDV--------- 506
            S     +PTT  G +    +L+ G  P  + P     VA++  S L +  V         
Sbjct: 2254 STEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTS 2313

Query: 507  ----KPKPIADAKA-PEKRASPSK------PASAPASRSGSKSTQTVAKTTTAAAVASTG 555
                 P P A+  + P   +S         P S     S   ST +     T+  V +  
Sbjct: 2314 TEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYS 2373

Query: 556  PSSRSPSTLLPKK-PTAIKTEGKP------------AEVKKMTAKSVPADLSRPKSTSTS 602
             +  SP+T      PT+  +EG                 +  T  + P D S P +TST 
Sbjct: 2374 QAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTE 2433

Query: 603  SMKKTTTLSGTAPAAGVVPSRVKATPMPSRP-STTPFIDKKPTSAKPSSTTP 653
            +    TT  GT+      P     TP+ S P STTP +    + A   STTP
Sbjct: 2434 ASSSPTTAEGTSIPTS--PPSEGTTPLASMPVSTTPVVS---SEAGTLSTTP 2480



 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 74/304 (24%), Positives = 109/304 (35%), Gaps = 24/304 (7%)

Query: 375 TKSRGLTPL--LPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSP 432
           T S G TPL  +P STI          S      +      S   +  TT  +  +  S 
Sbjct: 387 TLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATST 446

Query: 433 EKK------TKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAA 486
             +      + P++TT  A +  S   T P     Q   TT    +  P +     +P +
Sbjct: 447 PSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQV--TTSTEASSSPPTAEVNSMPTS 504

Query: 487 PPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASP---SKPASAPASRSGSKSTQTVA 543
            P   +        L S  V   P+A ++A     +P   S P +  +  S S +T    
Sbjct: 505 TPSEGSTP------LTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGT 558

Query: 544 KTTTAAAVASTGPSSRSP-STLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTS 602
              T+     + P +  P ST L     A  T   PA+       S  A  S   +  TS
Sbjct: 559 SIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTS 618

Query: 603 SMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKP----TSAKPSSTTPRLSRL 658
               T +  GT   +  V + + A+   S  STTP     P    T A  SSTT   + +
Sbjct: 619 MPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSM 678

Query: 659 ATNT 662
            T+T
Sbjct: 679 PTST 682



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 91/396 (22%), Positives = 141/396 (35%), Gaps = 59/396 (14%)

Query: 287  TELESVSLPTPEIQSDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETP----- 341
            T  E+ S PT    +   +S     PSE    L  +  S    L      +  TP     
Sbjct: 1723 TSTEARSSPTTSEGTSMPNST----PSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTST 1778

Query: 342  --QKMTEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLK 399
                 TE + S T  EG     S ++E            G+TPL           + +  
Sbjct: 1779 PVTTSTEATSSPTTAEGTSIPTSTLSE------------GMTPLTSTPVSHTLVANSEAS 1826

Query: 400  SAGIARPEEGRPVVSGT----------GNDITTPPNKELPPSPEKKTKPLATTQPAKTST 449
            +      +   PVV+ T          G  I T    E   S    + P++TT  A + T
Sbjct: 1827 TLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSE--GSTALTSIPVSTTTVASSET 1884

Query: 450  SKAKTQP--TSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVK 507
            +   T P  TS P     TT   ++  P +     +P + P+       RP  L S  V 
Sbjct: 1885 NTLSTTPAVTSTPV----TTYAQVSSSPTTADGSSMPTSTPRE-----GRPP-LTSIPVS 1934

Query: 508  PKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPK 567
               +A ++      + +   +   + S + S+ T A  T+    A +  S+  P T +P 
Sbjct: 1935 TTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGST--PLTSMPL 1992

Query: 568  KPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKAT 627
              T + +       +  T  + P D S P +TST      TT  GT+      PS  + T
Sbjct: 1993 STTLVVSS------EASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTS-TPSE-RTT 2044

Query: 628  PMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTS 663
            P+   P +T  +    +     STTP  S+     S
Sbjct: 2045 PLAGMPVSTTLV--VSSEGNTLSTTPVDSKTQVTNS 2078



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 85/396 (21%), Positives = 139/396 (35%), Gaps = 53/396 (13%)

Query: 287  TELESVSLPTPEIQSDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTE 346
            T L S+S+ T  + S    +    P            AS      E     + TP     
Sbjct: 2987 TPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTP----- 3041

Query: 347  KSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARP 406
             SE  TP        + +A P    +  T     +P++  + +       +  S  I+  
Sbjct: 3042 -SEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTY 3100

Query: 407  EEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPT 466
             EG   +  TG  ++T P      S    T P+ T+ P  TST +A + PT+      PT
Sbjct: 3101 SEGSTPL--TGVPVSTTPVTSSAIST-LSTTPVDTSTPVTTST-EAHSSPTTSEGTSMPT 3156

Query: 467  TIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP 526
            +       P++         P     V S+  S L +  V                    
Sbjct: 3157 STPSEGSTPLTYM-------PVSTMLVVSSEDSTLSATPVD------------------- 3190

Query: 527  ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTA 586
             S P + S   ++ T A+ T+     ST     +P T +P   T +      A  +    
Sbjct: 3191 TSTPVTTSTEATSSTTAEGTSIPT--STPSEGMTPLTSVPVSNTPV------ASSEASIL 3242

Query: 587  KSVPADLSRPKSTSTSSMKKTTTLSGTA-----PAAGVVPSRVKATPMPSRPSTTPFIDK 641
             + P D + P +TST +     T  GT+     P+ G  P     T MP   +T    + 
Sbjct: 3243 STTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTP----LTSMPVSTTTVASSET 3298

Query: 642  KPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGST 677
               S  P+ T+  ++  +  +S+P + +  S   ST
Sbjct: 3299 STLSTTPADTSTPVTTYSQASSSPPIADGTSMPTST 3334



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 75/292 (25%), Positives = 113/292 (38%), Gaps = 37/292 (12%)

Query: 417  GNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQP--------TSLPKQPAPTTI 468
            G  + TP   E   S    + PL+TT    +  S   T P        TS     +PTT 
Sbjct: 1972 GTSMPTPAYSE--GSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTA 2029

Query: 469  GGLNKKPMSLASGLVPAA--PPKRPAVASARPSILPSKDVKPKP----IADAKAPEKRAS 522
            GG + +  + +    P A  P     V S+  + L +  V  K       +A +      
Sbjct: 2030 GGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEG 2089

Query: 523  PSKPASAPASRSGSKSTQTVAKTTT------AAAVASTGPSSRSP---STLLPKKPTAIK 573
             S   SAP+   GS    ++  +TT      A+ +++T   S SP   ST +   P  I 
Sbjct: 2090 SSMTISAPSE--GSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSP--IP 2145

Query: 574  TEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGT-----APAAGVVPSRVKATP 628
            TEG   +    + +  P   S P ST+  +    +TLS T      P      +R   T 
Sbjct: 2146 TEGTSMQTSTYSDRRTPLT-SMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTT 2204

Query: 629  MP--SRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTE 678
                S P++TP     P ++ P ST P ++  A+  SA  +        STE
Sbjct: 2205 SEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTE 2256



 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 81/304 (26%), Positives = 114/304 (37%), Gaps = 65/304 (21%)

Query: 414  SGTGNDITTPPNKELPPSPEK----KTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIG 469
            S T   +T+ P    P +  +     T P+ T+ P  TST KA + PT+      P +  
Sbjct: 2806 SETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTST-KASSSPTTAEGIVVPISTA 2864

Query: 470  GLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPK-PIADA----KAPEKRASPS 524
                   S  S L+ + P     VAS+  S L +  V    P+  +     +P      S
Sbjct: 2865 -------SEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTS 2917

Query: 525  KPASAPA------------------SRSGSKSTQTVAKTT--TAAAVASTGPSSRSPSTL 564
             P S P+                  S + + ST  V   T  T +A AS+ P++   +++
Sbjct: 2918 MPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSM 2977

Query: 565  LPKKPTAIKTEGKPAEVKKM--------TAKSVPADLSRPKSTSTSSMKKTTTLSGT--- 613
                P   +T      V  M        T    PAD S P +TST +    TT  GT   
Sbjct: 2978 PISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIP 3037

Query: 614  --APAAGVVP-------SRVKATPMPSRPSTTPFIDKKP--TSAKPSST-TPRLSRLATN 661
               P+ G  P       +   A P  S  STTP     P  TS + SS+ TP     A  
Sbjct: 3038 ISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTP-----AEG 3092

Query: 662  TSAP 665
            TS P
Sbjct: 3093 TSMP 3096



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 95/440 (21%), Positives = 152/440 (34%), Gaps = 75/440 (17%)

Query: 287  TELESVSLPTPEIQSDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTE 346
            T  E  S+PT             +PPSE    L  M  S    +      +  TP   + 
Sbjct: 2439 TTAEGTSIPT-------------SPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTST 2485

Query: 347  KSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARP 406
               + T           +  P+      T S G T L             +  +      
Sbjct: 2486 PMTTSTEASSSPTTAEDIVVPIS-----TASEGSTLLTSIPVSTTPVASPEASTLSTTPV 2540

Query: 407  EEGRPVVSGT--GNDITTPPNKELPPSPEKK-----------TKPLATTQPAKTSTSKAK 453
            +   PVV+ T   +  T+     +P S   +           TKPLA+++ +  ST+   
Sbjct: 2541 DSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVD 2600

Query: 454  TQ---PTSLPKQPAPTT-------IGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPS 503
            T     TS     +PTT       I   ++   SL S LV   P     VAS+  S L +
Sbjct: 2601 TSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMP-----VASSEASTLST 2655

Query: 504  KDVKPKPIAD-----AKAPEKRASPSKPASAPASRS------------------GSKSTQ 540
              V  + +       + +P      S P S P  RS                   + ST 
Sbjct: 2656 TPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTT 2715

Query: 541  TVAKTT--TAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKS 598
             V  +T  T +A AS+ P++   +++    P+   T      V  +   S  A      +
Sbjct: 2716 PVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTA 2775

Query: 599  TSTSSMKKTTTLSGTAPAAGVVPSRVKATPM-PSRPSTTPFIDKKPTSAKPSSTTPRLSR 657
              TS    T+T + ++P    V S   +TP   S P T+  ++  P ++  + T   LS 
Sbjct: 2776 VDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGT---LST 2832

Query: 658  LATNTSAPDLKNVRSKVGST 677
               +TS P   + ++    T
Sbjct: 2833 TPVDTSTPVTTSTKASSSPT 2852



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 86/386 (22%), Positives = 140/386 (36%), Gaps = 53/386 (13%)

Query: 348 SESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIA--- 404
           +ES+T  E   +  +      +    PT   G    +P ST  E+     +     A   
Sbjct: 113 TESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTD--VPMSTPSEESISSTMAFVSTAPLP 170

Query: 405 ----------RPEEGRPVVSGT--GNDITTPPNKELPPSPEKKTKPLATTQPAKT---ST 449
                     + +   P+ + T   +  TTP +  +P S   +     T+ PA T   ++
Sbjct: 171 SFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVAS 230

Query: 450 SKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILP------- 502
           S+A T  T+  +   P TI        + A G  P+     P+  S   + +P       
Sbjct: 231 SEAITLLTTPVEISTPVTISAQASSSPTTAEG--PSLSNSAPSGGSTPLTRMPLSVMLVV 288

Query: 503 SKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK---STQTVAKTTTAAAVASTGPSSR 559
           S +        A       + ++ +S+P +  G+    ST T   T   +  AST P + 
Sbjct: 289 SSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVAT 348

Query: 560 SPSTLLPKKP----TAIKTEGKPAEVKKMT-AKSVPADLSRPKSTSTSSMKKTTTL--SG 612
           S  + L   P    T + T  +P+ +     A S+        ST  ++M  +T L  S 
Sbjct: 349 SEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASS 408

Query: 613 TAPAAGVVPSRVK-----ATPMPSRPST---------TPFIDKKPTSAKPSSTTPRLSRL 658
            A     +P   K     A+   S P+T         TP     P ++ P STTP  S  
Sbjct: 409 EASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSE 468

Query: 659 ATNTSAPDLKNVRSKVGSTENIKHQP 684
           A+N S   + +      STE     P
Sbjct: 469 ASNLSTTPVDSKTQVTTSTEASSSPP 494



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 75/313 (23%), Positives = 114/313 (36%), Gaps = 42/313 (13%)

Query: 375  TKSRGLTPL--LPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSP 432
            T S G TPL  +P ST           S   A         S   +  TT     +P S 
Sbjct: 1036 TPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTST 1095

Query: 433  EKKTKPLATTQPAKTS---TSKAKTQPTSLPKQPAP-TTIGGLNKKPMSLASGLVPAAPP 488
              +     T+ P  T    +S+A T  T+      P TT    +  P +     +P +PP
Sbjct: 1096 YSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPP 1155

Query: 489  KRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTA 548
                  S   + L S  V    +  ++A     +P    +  A+ + + S    A+ T+ 
Sbjct: 1156 ------SEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTS- 1208

Query: 549  AAVASTGPSSRS-PSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKT 607
              + ++ P  RS P T +P + T +      A  +  T  + P D S P +TS  +    
Sbjct: 1209 --MPTSTPGERSTPLTSMPVRHTPV------ASSEASTLSTSPVDTSTPVTTSAETSSSP 1260

Query: 608  TTLSGTAPAAGV------------VPSRVKATPMPSRPSTTPFIDKKP---TSAKPSSTT 652
            TT  GT+                 V + +  +P  S   TTP   K P   ++   SS T
Sbjct: 1261 TTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPT 1320

Query: 653  PRLSRLATNTSAP 665
            P     A  TS P
Sbjct: 1321 P-----AEGTSMP 1328



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 97/409 (23%), Positives = 136/409 (33%), Gaps = 73/409 (17%)

Query: 287  TELESVSLPTPEIQSDFLHSKVEAPPSEVADTLVIMTASKGVRLPEPKDKILETP----- 341
            T  E  S+PT             + PSE    L  M  S    +    + +  TP     
Sbjct: 3382 TTAEGTSIPT-------------SSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNT 3428

Query: 342  --QKMTEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPL--LPKSTIQEQERHKQ 397
                 TE S S T  EG     S            T S G TPL  +P ST         
Sbjct: 3429 LVTTSTEASSSPTIAEGTSLPTS------------TTSEGSTPLSIMPLSTTPVASSEAS 3476

Query: 398  LKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPT 457
              S             S T +  TT     +P S   +     T  P  T T  A ++ +
Sbjct: 3477 TLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVST-TPVASSEAS 3535

Query: 458  SLPKQPAP-----TTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIA 512
            +L   P       T+    +  P +L    +  + P   + +S    +L S  V     +
Sbjct: 3536 TLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGS-SSLTTMLLSSTYVTS---S 3591

Query: 513  DAKAPEKRASPSKPASAPASRSG-SKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTA 571
            +A  P   ++PS   S P + S  S ST T  +  T     ST     +P T++P   T+
Sbjct: 3592 EASTP---STPSVDRSTPVTTSTQSNSTPTPPEVITLPM--STPSEVSTPLTIMPVSTTS 3646

Query: 572  IKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPS 631
            +         +  TA ++P D S P  TST       T  GT                 +
Sbjct: 3647 VTIS------EAGTASTLPVDTSTPVITSTQVSSSPVTPEGT-----------------T 3683

Query: 632  RPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENI 680
             P  TP     P +  P STT   S   +  S P +        STE I
Sbjct: 3684 MPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAI 3732



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 60/262 (22%), Positives = 99/262 (37%), Gaps = 25/262 (9%)

Query: 436 TKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPM-SLASGLVPAAPPKRPAVA 494
           T P AT  P  TST +A + PT+      PT+       P+ S  +  +P A  +   ++
Sbjct: 297 TTPAATNIPVITST-EASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLS 355

Query: 495 ------------SARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTV 542
                       S  PS LP+       +    +       + P S     S   ST + 
Sbjct: 356 ITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTST 415

Query: 543 AKTTTAAAVASTGPSSRSPSTLLPKK-PTAIKTEGKPAEVKKMTAKSVPADLSRPKSTST 601
               +   V +   +S SP+T       T+  +EG    +  M   + P   S   + ST
Sbjct: 416 IPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGS-TPLTSMPVSTTPVASSEASNLST 474

Query: 602 SSMKK-----TTTLSGTAPAAGVVPSRVKATPMP-SRPSTTPFIDKKPTSAKPSSTTPRL 655
           + +       T+T + ++P    V S   +TP   S P T+  +   P ++  +ST   L
Sbjct: 475 TPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEAST---L 531

Query: 656 SRLATNTSAPDLKNVRSKVGST 677
           S    +TS P   +  +   ST
Sbjct: 532 STTPVDTSTPVTTSSEASSSST 553



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 94/445 (21%), Positives = 147/445 (33%), Gaps = 69/445 (15%)

Query: 253 SKGSDSLNKKVDLTLLSPKSENDKLKEISLACKI---TELESVSLPTPEIQSDFLHSKVE 309
           S+GS  L      T+L   SE      I +  K    T  E+ S PT    +    S   
Sbjct: 389 SEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATST-- 446

Query: 310 APPSEVADTLVIMTASKGVRLPEPKDKILETPQKMTEKSESKTPGEGKKEDKSRMAEPMK 369
             PSE +  L  M  S           +  TP  +  K++  T  E      +     M 
Sbjct: 447 --PSEGSTPLTSMPVSTTPVASSEASNLSTTP--VDSKTQVTTSTEASSSPPTAEVNSMP 502

Query: 370 GYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELP 429
                T S G TPL   S                       PV S   + ++T P     
Sbjct: 503 ---TSTPSEGSTPLTSMSV-------------------STMPVASSEASTLSTTPVDTST 540

Query: 430 PSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPK 489
           P         ++T P  TS       PTS P +      G      M +++ LV ++   
Sbjct: 541 PVTTSSEASSSSTTPEGTSI------PTSTPSE------GSTPLTNMPVSTRLVVSSEAS 588

Query: 490 RPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAA 549
             +   A  +           +  +      ++ ++  S P S    + T   + + +  
Sbjct: 589 TTSTTPADSNTF---------VTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTT 639

Query: 550 AVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTT 609
            VAS+  S+ S + +    P    TE   +        S+P       ST  +SM   TT
Sbjct: 640 LVASSEASTLSTTPVDSNTPVTTSTEATSSST-TAEGTSMPTSTYTEGSTPLTSMPVNTT 698

Query: 610 LSGTAPAAGV----------VPSRVKATPMP------SRPSTTPFIDKKPTSAKPSSTTP 653
           L  ++ A+ +          V +  +A+  P      S P++TP     P ++ P S T 
Sbjct: 699 LVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTL 758

Query: 654 RLSRLATNTSAPDLKNVRSKVGSTE 678
             S  A+  S   L        STE
Sbjct: 759 LTSSEASTLSTTPLDTSTHITTSTE 783



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 99/454 (21%), Positives = 163/454 (35%), Gaps = 69/454 (15%)

Query: 311  PPSEVADTLVIMTASKG----VRLPEPKDKI--LETPQKMTEKSESKTPGEGKKEDKSRM 364
            PP+    ++   T+S+G     R+P     +   ET    T  +++ TP     +  S  
Sbjct: 2320 PPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSP 2379

Query: 365  AEPMKGYM-RPTKSRGLTPL--LPKSTIQEQERHKQLKSAGIARPEEGRPVVSGT--GND 419
                   M   T S G TPL  +P ST+          S      +   PV + T   + 
Sbjct: 2380 TTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHST--TPVDTSTPVTTSTEASSS 2437

Query: 420  ITTPPNKELPPSPEKK------TKPLATTQPAKTSTSKAKTQP--------TSLPKQPAP 465
             TT     +P SP  +      + P++TT    +      T P        TS     +P
Sbjct: 2438 PTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSP 2497

Query: 466  TTIGGLNKKPMSLASG---LVPAAPPKRPAVASARPSILPSKDVKPK-PIADAKAPEKRA 521
            TT   +   P+S AS    L+ + P     VAS   S L +  V    P+  +      A
Sbjct: 2498 TTAEDI-VVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSA 2556

Query: 522  SPSKPASAPAS---------RSGSKSTQTVAKT---------------TTAAAVASTGPS 557
            + ++  S P S         RS   ST+ +A +                T +   S+ P+
Sbjct: 2557 TSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPT 2616

Query: 558  SRSPSTLLPKKPTAIKTEGKPAEVKKM--------TAKSVPADLSRPKSTSTSSMKKTTT 609
            +   +++    P+ + T      V  M        T  + P D     +TST +    TT
Sbjct: 2617 TAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTT 2676

Query: 610  LSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKN 669
              G++        R  +TP+ +   +T  +    + A   STTP  +     TSA    +
Sbjct: 2677 AEGSSMPTSTPGER--STPLTNILVSTTLLAN--SEASTLSTTPVDTSTPVTTSAEASSS 2732

Query: 670  VRSKVGSTENIKHQPGGGRVQIQNKKVDISKVSS 703
              +  G++  I   P  G   + +  V    V+S
Sbjct: 2733 PTTAEGTSMRIS-TPSDGSTPLTSILVSTLPVAS 2765



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 53/242 (21%), Positives = 86/242 (35%), Gaps = 15/242 (6%)

Query: 374  PTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPE 433
            P+     TP +P +T        +  + G        PV S T +           P   
Sbjct: 3908 PSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVIT 3967

Query: 434  KKTKPLATTQPAKTSTSKAKTQPTSLPKQP--APTTIGGLNKKPMSLASGLVPAAPPKRP 491
                   +T  + T+TS + T+  + P     AP T   ++  P +  +           
Sbjct: 3968 STELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSAST 4027

Query: 492  AVASARPSILPSKDVKP-KPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAA 550
              A++ P    S   +P  P +++  P    S + P + P + S +  T + + TT    
Sbjct: 4028 LSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPE 4087

Query: 551  VASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTL 610
              +T  +   PST     PT   T    A     T KS P        TST ++ +TTT 
Sbjct: 4088 AVTTMTTRTKPSTRTTSFPTVTTT----AVPTNTTIKSNP--------TSTPTVPRTTTC 4135

Query: 611  SG 612
             G
Sbjct: 4136 FG 4137



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 67/333 (20%), Positives = 117/333 (35%), Gaps = 32/333 (9%)

Query: 344  MTEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGI 403
            +T  S++ +     +    RM+ P +G      S  LT +L  ST           +  +
Sbjct: 3548 VTSSSQASSSPATLQVTTMRMSTPSEG------SSSLTTMLLSSTYVTSSEASTPSTPSV 3601

Query: 404  ARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQP 463
             R     PV + T ++ T  P       PE  T P++T     T  +      TS+    
Sbjct: 3602 DR---STPVTTSTQSNSTPTP-------PEVITLPMSTPSEVSTPLTIMPVSTTSVTISE 3651

Query: 464  APTTIGGLNKKPMSLASGLVPAAPPKRPAVA---SARPSILPSKDVKPKPIADAKAPEKR 520
            A T     +  P+  ++ ++ +       V    +  P   PS+   P            
Sbjct: 3652 AGTA----STLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVT 3707

Query: 521  ASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAE 580
            +S     S P+  + +  T +    +++A + ST  S   P  +     T + +      
Sbjct: 3708 SSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTR 3767

Query: 581  VKKMTAKSVPA-DLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFI 639
              + +  S+P+   S   +T++      TTL GT          +  T   S   TT  I
Sbjct: 3768 FPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMP------MSTTSERSTLLTTVLI 3821

Query: 640  DKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRS 672
               P S    S    LS    +TS P L + ++
Sbjct: 3822 --SPISVMSPSEASTLSTPPGDTSTPLLTSTKA 3852


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.303    0.123    0.338 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,611,381
Number of Sequences: 37866
Number of extensions: 2082947
Number of successful extensions: 17647
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 197
Number of HSP's successfully gapped in prelim test: 1367
Number of HSP's that attempted gapping in prelim test: 9255
Number of HSP's gapped (non-prelim): 5438
length of query: 817
length of database: 18,247,518
effective HSP length: 111
effective length of query: 706
effective length of database: 14,044,392
effective search space: 9915340752
effective search space used: 9915340752
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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