Guide to the Human Genome
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Search of human proteins with 195963418

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|195963418 tubulin tyrosine ligase-like family, member 6
isoform 1 [Homo sapiens]
         (891 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|195963418 tubulin tyrosine ligase-like family, member 6 isofo...  1808   0.0  
gi|195963416 tubulin tyrosine ligase-like family, member 6 isofo...  1122   0.0  
gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo...   550   e-156
gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo ...   372   e-103
gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo...   221   2e-57
gi|212720861 tubulin tyrosine ligase-like family, member 11 a [H...   218   3e-56
gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo ...   213   8e-55
gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo ...   194   3e-49
gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo ...   186   1e-46
gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Ho...   182   1e-45
gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo ...   158   2e-38
gi|194239681 tubulin tyrosine ligase-like family, member 10 isof...    98   4e-20
gi|24308516 tubulin tyrosine ligase [Homo sapiens]                     97   9e-20
gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo...    84   4e-16
gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo...    70   7e-12
gi|194239678 tubulin tyrosine ligase-like family, member 10 isof...    64   6e-10
gi|11056036 tubulin tyrosine ligase-like family, member 12 [Homo...    52   2e-06
gi|31542634 filamin A interacting protein 1 [Homo sapiens]             41   0.006
gi|117190342 PHD finger protein 2 [Homo sapiens]                       40   0.010
gi|46399200 testis-specific bromodomain protein [Homo sapiens]         37   0.063
gi|46399198 testis-specific bromodomain protein [Homo sapiens]         37   0.063
gi|149773468 RAD51 associated protein 2 [Homo sapiens]                 37   0.082
gi|53829376 plakophilin 4 isoform b [Homo sapiens]                     36   0.14 
gi|53829374 plakophilin 4 isoform a [Homo sapiens]                     36   0.14 
gi|151301053 RNA binding motif protein 33 [Homo sapiens]               36   0.14 
gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo sap...    36   0.14 
gi|120587019 zinc finger protein 318 [Homo sapiens]                    36   0.14 
gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]              36   0.18 
gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]             36   0.18 
gi|148746195 trichohyalin [Homo sapiens]                               36   0.18 

>gi|195963418 tubulin tyrosine ligase-like family, member 6 isoform
           1 [Homo sapiens]
          Length = 891

 Score = 1808 bits (4684), Expect = 0.0
 Identities = 891/891 (100%), Positives = 891/891 (100%)

Query: 1   MGALLLHPSRRGPAGVVASWTSSPAGRDGGVGIAGAWYFPRASSQAREMPQCPTLESQEG 60
           MGALLLHPSRRGPAGVVASWTSSPAGRDGGVGIAGAWYFPRASSQAREMPQCPTLESQEG
Sbjct: 1   MGALLLHPSRRGPAGVVASWTSSPAGRDGGVGIAGAWYFPRASSQAREMPQCPTLESQEG 60

Query: 61  ENSEEKGDSSKEDPKETVALAFVRENPGAQNGLQNAQQQGKKKRKKKRLVINLSSCRYES 120
           ENSEEKGDSSKEDPKETVALAFVRENPGAQNGLQNAQQQGKKKRKKKRLVINLSSCRYES
Sbjct: 61  ENSEEKGDSSKEDPKETVALAFVRENPGAQNGLQNAQQQGKKKRKKKRLVINLSSCRYES 120

Query: 121 VRRAAQQYGFREGGEDDDWTLYWTDYSVSLERVMEMKSYQKINHFPGMSEICRKDLLARN 180
           VRRAAQQYGFREGGEDDDWTLYWTDYSVSLERVMEMKSYQKINHFPGMSEICRKDLLARN
Sbjct: 121 VRRAAQQYGFREGGEDDDWTLYWTDYSVSLERVMEMKSYQKINHFPGMSEICRKDLLARN 180

Query: 181 MSRMLKMFPKDFRFFPRTWCLPADWGDLQTYSRSRKNKTYICKPDSGCQGKGIFITRTVK 240
           MSRMLKMFPKDFRFFPRTWCLPADWGDLQTYSRSRKNKTYICKPDSGCQGKGIFITRTVK
Sbjct: 181 MSRMLKMFPKDFRFFPRTWCLPADWGDLQTYSRSRKNKTYICKPDSGCQGKGIFITRTVK 240

Query: 241 EIKPGEDMICQLYISKPFIIDGFKFDLRIYVLVTSCDPLRIFVYNEGLARFATTSYSRPC 300
           EIKPGEDMICQLYISKPFIIDGFKFDLRIYVLVTSCDPLRIFVYNEGLARFATTSYSRPC
Sbjct: 241 EIKPGEDMICQLYISKPFIIDGFKFDLRIYVLVTSCDPLRIFVYNEGLARFATTSYSRPC 300

Query: 301 TDNLDDICMHLTNYSINKHSSNFSRDAHSGSKRKLSTFSAYLEDHSYNVEQIWRDIEDVI 360
           TDNLDDICMHLTNYSINKHSSNFSRDAHSGSKRKLSTFSAYLEDHSYNVEQIWRDIEDVI
Sbjct: 301 TDNLDDICMHLTNYSINKHSSNFSRDAHSGSKRKLSTFSAYLEDHSYNVEQIWRDIEDVI 360

Query: 361 IKTLISAHPIIRHNYHTCFPNHTLNSACFEILGFDILLDHKLKPWLLEVNHSPSFSTDSR 420
           IKTLISAHPIIRHNYHTCFPNHTLNSACFEILGFDILLDHKLKPWLLEVNHSPSFSTDSR
Sbjct: 361 IKTLISAHPIIRHNYHTCFPNHTLNSACFEILGFDILLDHKLKPWLLEVNHSPSFSTDSR 420

Query: 421 LDKEVKDGLLYDTLVLINLESCDKKKVLEEERQRGQFLQQCCSREMRIEEAKGFRAVQLK 480
           LDKEVKDGLLYDTLVLINLESCDKKKVLEEERQRGQFLQQCCSREMRIEEAKGFRAVQLK
Sbjct: 421 LDKEVKDGLLYDTLVLINLESCDKKKVLEEERQRGQFLQQCCSREMRIEEAKGFRAVQLK 480

Query: 481 KTETYEKENCGGFRLIYPSLNSEKYEKFFQDNNSLFQNTVASRAREEYARQLIQELRLKR 540
           KTETYEKENCGGFRLIYPSLNSEKYEKFFQDNNSLFQNTVASRAREEYARQLIQELRLKR
Sbjct: 481 KTETYEKENCGGFRLIYPSLNSEKYEKFFQDNNSLFQNTVASRAREEYARQLIQELRLKR 540

Query: 541 EKKPFQMKKKVEMQGESAGEQVRKKGMRGWQQKQQQKDKAATQASKQYIQPLTLVSYTPD 600
           EKKPFQMKKKVEMQGESAGEQVRKKGMRGWQQKQQQKDKAATQASKQYIQPLTLVSYTPD
Sbjct: 541 EKKPFQMKKKVEMQGESAGEQVRKKGMRGWQQKQQQKDKAATQASKQYIQPLTLVSYTPD 600

Query: 601 LLLSVRGERKNETDSSLNQEAPTEEASSVFPKLTSAKPFSSLPDLRNINLSSSKLEPSKP 660
           LLLSVRGERKNETDSSLNQEAPTEEASSVFPKLTSAKPFSSLPDLRNINLSSSKLEPSKP
Sbjct: 601 LLLSVRGERKNETDSSLNQEAPTEEASSVFPKLTSAKPFSSLPDLRNINLSSSKLEPSKP 660

Query: 661 NFSIKEAKSASAVNVFTGTVHLTSVETTPESTTQLSISPKSPPTLAVTASSEYSGPETDR 720
           NFSIKEAKSASAVNVFTGTVHLTSVETTPESTTQLSISPKSPPTLAVTASSEYSGPETDR
Sbjct: 661 NFSIKEAKSASAVNVFTGTVHLTSVETTPESTTQLSISPKSPPTLAVTASSEYSGPETDR 720

Query: 721 VVSFKCKKQQTPPHLTQKKMLKSFLPTKSKSFWESPNTNWTLLKSDMNKPHLISELLTKL 780
           VVSFKCKKQQTPPHLTQKKMLKSFLPTKSKSFWESPNTNWTLLKSDMNKPHLISELLTKL
Sbjct: 721 VVSFKCKKQQTPPHLTQKKMLKSFLPTKSKSFWESPNTNWTLLKSDMNKPHLISELLTKL 780

Query: 781 QLSGKLSFFPAHYNPKLGMNNLSQNPSLPGECHSRSDSSGEKRQLDVSSLLLQSPQSYNV 840
           QLSGKLSFFPAHYNPKLGMNNLSQNPSLPGECHSRSDSSGEKRQLDVSSLLLQSPQSYNV
Sbjct: 781 QLSGKLSFFPAHYNPKLGMNNLSQNPSLPGECHSRSDSSGEKRQLDVSSLLLQSPQSYNV 840

Query: 841 TLRDLLVIATPAQLDPRPCRSHASAMRDPCMQDQEAYSHCLISGQKGCERS 891
           TLRDLLVIATPAQLDPRPCRSHASAMRDPCMQDQEAYSHCLISGQKGCERS
Sbjct: 841 TLRDLLVIATPAQLDPRPCRSHASAMRDPCMQDQEAYSHCLISGQKGCERS 891


>gi|195963416 tubulin tyrosine ligase-like family, member 6 isoform
           2 [Homo sapiens]
          Length = 584

 Score = 1122 bits (2901), Expect = 0.0
 Identities = 559/559 (100%), Positives = 559/559 (100%)

Query: 333 RKLSTFSAYLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNSACFEIL 392
           RKLSTFSAYLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNSACFEIL
Sbjct: 26  RKLSTFSAYLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNSACFEIL 85

Query: 393 GFDILLDHKLKPWLLEVNHSPSFSTDSRLDKEVKDGLLYDTLVLINLESCDKKKVLEEER 452
           GFDILLDHKLKPWLLEVNHSPSFSTDSRLDKEVKDGLLYDTLVLINLESCDKKKVLEEER
Sbjct: 86  GFDILLDHKLKPWLLEVNHSPSFSTDSRLDKEVKDGLLYDTLVLINLESCDKKKVLEEER 145

Query: 453 QRGQFLQQCCSREMRIEEAKGFRAVQLKKTETYEKENCGGFRLIYPSLNSEKYEKFFQDN 512
           QRGQFLQQCCSREMRIEEAKGFRAVQLKKTETYEKENCGGFRLIYPSLNSEKYEKFFQDN
Sbjct: 146 QRGQFLQQCCSREMRIEEAKGFRAVQLKKTETYEKENCGGFRLIYPSLNSEKYEKFFQDN 205

Query: 513 NSLFQNTVASRAREEYARQLIQELRLKREKKPFQMKKKVEMQGESAGEQVRKKGMRGWQQ 572
           NSLFQNTVASRAREEYARQLIQELRLKREKKPFQMKKKVEMQGESAGEQVRKKGMRGWQQ
Sbjct: 206 NSLFQNTVASRAREEYARQLIQELRLKREKKPFQMKKKVEMQGESAGEQVRKKGMRGWQQ 265

Query: 573 KQQQKDKAATQASKQYIQPLTLVSYTPDLLLSVRGERKNETDSSLNQEAPTEEASSVFPK 632
           KQQQKDKAATQASKQYIQPLTLVSYTPDLLLSVRGERKNETDSSLNQEAPTEEASSVFPK
Sbjct: 266 KQQQKDKAATQASKQYIQPLTLVSYTPDLLLSVRGERKNETDSSLNQEAPTEEASSVFPK 325

Query: 633 LTSAKPFSSLPDLRNINLSSSKLEPSKPNFSIKEAKSASAVNVFTGTVHLTSVETTPEST 692
           LTSAKPFSSLPDLRNINLSSSKLEPSKPNFSIKEAKSASAVNVFTGTVHLTSVETTPEST
Sbjct: 326 LTSAKPFSSLPDLRNINLSSSKLEPSKPNFSIKEAKSASAVNVFTGTVHLTSVETTPEST 385

Query: 693 TQLSISPKSPPTLAVTASSEYSGPETDRVVSFKCKKQQTPPHLTQKKMLKSFLPTKSKSF 752
           TQLSISPKSPPTLAVTASSEYSGPETDRVVSFKCKKQQTPPHLTQKKMLKSFLPTKSKSF
Sbjct: 386 TQLSISPKSPPTLAVTASSEYSGPETDRVVSFKCKKQQTPPHLTQKKMLKSFLPTKSKSF 445

Query: 753 WESPNTNWTLLKSDMNKPHLISELLTKLQLSGKLSFFPAHYNPKLGMNNLSQNPSLPGEC 812
           WESPNTNWTLLKSDMNKPHLISELLTKLQLSGKLSFFPAHYNPKLGMNNLSQNPSLPGEC
Sbjct: 446 WESPNTNWTLLKSDMNKPHLISELLTKLQLSGKLSFFPAHYNPKLGMNNLSQNPSLPGEC 505

Query: 813 HSRSDSSGEKRQLDVSSLLLQSPQSYNVTLRDLLVIATPAQLDPRPCRSHASAMRDPCMQ 872
           HSRSDSSGEKRQLDVSSLLLQSPQSYNVTLRDLLVIATPAQLDPRPCRSHASAMRDPCMQ
Sbjct: 506 HSRSDSSGEKRQLDVSSLLLQSPQSYNVTLRDLLVIATPAQLDPRPCRSHASAMRDPCMQ 565

Query: 873 DQEAYSHCLISGQKGCERS 891
           DQEAYSHCLISGQKGCERS
Sbjct: 566 DQEAYSHCLISGQKGCERS 584


>gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo
           sapiens]
          Length = 459

 Score =  550 bits (1417), Expect = e-156
 Identities = 253/370 (68%), Positives = 309/370 (83%), Gaps = 4/370 (1%)

Query: 101 KKKRKKKRLVINLSSCRYESVRRAAQQYGFREGGEDDDWTLYWTDYSVSLERVMEMKSYQ 160
           K++RK++ L INL++C+YESVRRAAQ  G +E GED++WTLYWTD +VSLERVM+MK +Q
Sbjct: 80  KRRRKRRSLAINLTNCKYESVRRAAQMCGLKEVGEDEEWTLYWTDCAVSLERVMDMKRFQ 139

Query: 161 KINHFPGMSEICRKDLLARNMSRMLKMFPKDFRFFPRTWCLPADWGDLQTYSRSRKNKTY 220
           KINHFPGM+EICRKDLLARN++RM K++P ++  FPRTWCLPAD+GD Q+Y R RK +TY
Sbjct: 140 KINHFPGMTEICRKDLLARNLNRMYKLYPSEYNIFPRTWCLPADYGDFQSYGRQRKARTY 199

Query: 221 ICKPDSGCQGKGIFITRTVKEIKPGEDMICQLYISKPFIIDGFKFDLRIYVLVTSCDPLR 280
           ICKPDSGCQG+GIFITR  +EIKPGE MICQ YISKP +IDGFKFD+R+YVL+TSCDPLR
Sbjct: 200 ICKPDSGCQGRGIFITRNPREIKPGEHMICQQYISKPLLIDGFKFDMRVYVLITSCDPLR 259

Query: 281 IFVYNEGLARFATTSYSRPCTDNLDDICMHLTNYSINKHSSNFSRDAHSGSKRKLSTFSA 340
           IF Y EGLARFATT Y  P  +NLD++CMHLTNY+INKH+ NF RD   GSKRKLST + 
Sbjct: 260 IFTYEEGLARFATTPYMEPSHNNLDNVCMHLTNYAINKHNENFVRDGAVGSKRKLSTLNI 319

Query: 341 YLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNS---ACFEILGFDIL 397
           +L++HSYN  ++W DIED+IIKT+ISAH ++RHNY TCFP + LN    ACFEILGFDIL
Sbjct: 320 WLQEHSYNPGELWGDIEDIIIKTIISAHSVLRHNYRTCFPQY-LNGGTCACFEILGFDIL 378

Query: 398 LDHKLKPWLLEVNHSPSFSTDSRLDKEVKDGLLYDTLVLINLESCDKKKVLEEERQRGQF 457
           LDHKLKPWLLEVNHSPSF+TDS LD+EVKD LL D + L+NL  CDK+KV+EE+++R + 
Sbjct: 379 LDHKLKPWLLEVNHSPSFTTDSCLDQEVKDALLCDAMTLVNLRGCDKRKVMEEDKRRVKE 438

Query: 458 LQQCCSREMR 467
               C R+ R
Sbjct: 439 RLFQCYRQPR 448


>gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo
           sapiens]
          Length = 887

 Score =  372 bits (955), Expect = e-103
 Identities = 198/497 (39%), Positives = 297/497 (59%), Gaps = 33/497 (6%)

Query: 101 KKKRKKKRLVINLSSCRYESVRRAAQQYGFREGGEDDDWT-LYWTDYSVSLERVMEMKSY 159
           +KK+KK  +  N++  ++E VR    + GF +  ++D+ + L W D +V  E++ E+++Y
Sbjct: 33  RKKKKKGTITANVAGTKFEIVRLVIDEMGFMKTPDEDETSNLIWCDSAVQQEKISELQNY 92

Query: 160 QKINHFPGMSEICRKDLLARNMSRMLKMFPKDFRFFPRTWCLPADWGDLQTY----SRSR 215
           Q+INHFPGM EICRKD LARNM++M+K  P D+ F PRTW  PA++   Q Y     + R
Sbjct: 93  QRINHFPGMGEICRKDFLARNMTKMIKSRPLDYTFVPRTWIFPAEYTQFQNYVKELKKKR 152

Query: 216 KNKTYICKPDSGCQGKGIFITRTVKEIKPGEDMICQLYISKPFIIDGFKFDLRIYVLVTS 275
           K KT+I KP +G  G GI + R   ++   + +I Q YI KPF+++G+KFDLRIY+LVTS
Sbjct: 153 KQKTFIVKPANGAMGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTS 212

Query: 276 CDPLRIFVYNEGLARFATTSYSRPCTDNLDDICMHLTNYSINKHSSNFSRD--AHSGSKR 333
           CDPL+IF+Y++GL R  T  Y  P   NL  + MHLTNYS+NKH+ +F RD   + GSKR
Sbjct: 213 CDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKR 272

Query: 334 KLSTFSAYLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHT--LNSACFEI 391
            +  F+ +L+ + ++V + W DI ++++KTLI A P + H Y  C P       S CFE+
Sbjct: 273 SIKWFTEFLQANQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEV 332

Query: 392 LGFDILLDHKLKPWLLEVNHSPSFSTDSRLDKEVKDGLLYDTLVLINLESCDKKKVLEEE 451
           LGFDILLD KLKPWLLE+N +PSF TD ++D +VK G+L + L L+N+ + DK++ L ++
Sbjct: 333 LGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIRTSDKRRNLAKQ 392

Query: 452 RQRGQ------------------FLQQCCSREMRIEEAKGFRAVQLKK---TETYEKENC 490
           +   Q                  + QQ    E R EE K  R  Q++K    E +E  + 
Sbjct: 393 KAEAQRRLYGQNSIKRLLPGSSDWEQQRHQLERRKEELKE-RLAQVRKQISREEHENRHM 451

Query: 491 GGFRLIYPSLNSEKYEKFFQDNNSLFQNTVASRAREEYARQLIQELRLKREKKPFQMKKK 550
           G +R IYP  +    EK+       FQ  ++ RA   + R+L   L+  +E+    + ++
Sbjct: 452 GNYRRIYPPEDKALLEKYENLLAVAFQTFLSGRA-ASFQRELNNPLKRMKEEDILDLLEQ 510

Query: 551 VEMQGES-AGEQVRKKG 566
            E+  E   G+  + +G
Sbjct: 511 CEIDDEKLMGKTTKTRG 527


>gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo
           sapiens]
          Length = 1199

 Score =  221 bits (563), Expect = 2e-57
 Identities = 144/415 (34%), Positives = 212/415 (51%), Gaps = 46/415 (11%)

Query: 61  ENSEEKGDS-----SKEDPKETVALA---------------------------FVRENPG 88
           EN EE+GDS     S   P E+VA+                            F    P 
Sbjct: 527 ENEEEEGDSECSSLSAVSPSESVAMISRSCMEILTKPLSNHEKVVRPALIYSLFPNVPPT 586

Query: 89  AQNGLQNAQQQGKKKRKKKRLVINLSSCRYESVRRAAQQYGFREGGEDDDWTLYWTDYSV 148
              G ++ + +     ++K L   +S+     V++   +  F+    +DDW   W  +  
Sbjct: 587 IYFGTRDERVEKLPWEQRKLLRWKMSTVTPNIVKQTIGRSHFKISKRNDDWLGCWGHHMK 646

Query: 149 SLERVMEMKSYQKINHFPGMSEICRKDLLARNMSRMLKMF-PKDFRFFPRTWCLPADWGD 207
           S      ++ +QK+NHFPG  +I RKD L RN+SRM   F  K+F FFP+++ LP D   
Sbjct: 647 S-PSFRSIREHQKLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDAKL 705

Query: 208 LQTYSRSRKNKTYICKPDSGCQGKGIFITRTVKEIKPGEDMICQLYISKPFIIDGFKFDL 267
           L+    S   + +I KP +  +G GI +     ++     ++ Q Y+ KP++I G KFDL
Sbjct: 706 LRKAWESSSRQKWIVKPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDL 765

Query: 268 RIYVLVTSCDPLRIFVYNEGLARFATTSYSRPCTDNLDDICMHLTNYSINKHSSNFSRDA 327
           RIYV VTS DPLRI+++++GL RFA+  YS P   +L +  MHLTNYS+NK ++ +  +A
Sbjct: 766 RIYVYVTSYDPLRIYLFSDGLVRFASCKYS-PSMKSLGNKFMHLTNYSVNKKNAEYQANA 824

Query: 328 H----SGSKRKLSTFSAYLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHT 383
                 G K  L     YL     N + IW  I+DV++KT+IS+ P     Y T      
Sbjct: 825 DEMACQGHKWALKALWNYLSQKGVNSDAIWEKIKDVVVKTIISSEP-----YVTSLLKMY 879

Query: 384 LNS--ACFEILGFDILLDHKLKPWLLEVNHSPSFSTDSRLDKEVKDGLLYDTLVL 436
           +    +C E+ GFDI+LD  LKPW+LEVN SPS  + S LD  +K  ++ D L L
Sbjct: 880 VRRPYSCHELFGFDIMLDENLKPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNL 934


>gi|212720861 tubulin tyrosine ligase-like family, member 11 a [Homo
           sapiens]
          Length = 800

 Score =  218 bits (554), Expect = 3e-56
 Identities = 121/305 (39%), Positives = 175/305 (57%), Gaps = 27/305 (8%)

Query: 161 KINHFPGMSEICRKDLLARNMSRMLKMFPKDFRFFPRTWCLPADWGDLQTYSRSRKNK-- 218
           ++N FPGM+E+ RK  L+R +  M  +FP+++ F+PR+W LP ++       +  K+   
Sbjct: 271 QVNKFPGMTEMVRKITLSRAVRTMQNLFPEEYNFYPRSWILPDEFQLFVAQVQMVKDDDP 330

Query: 219 ----TYICKPDSGCQGKGIFITRTVKEIK-----PGEDMICQLYISKPFIIDGFKFDLRI 269
               T+I KPD GCQG GI++ +   +I+          + Q YI KP +ID  KFD+R+
Sbjct: 331 SWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLLIDKLKFDIRL 390

Query: 270 YVLVTSCDPLRIFVYNEGLARFATTSYSRPCTDNLDDICMHLTNYSINKHSSNF--SRDA 327
           YVL+ S DPL I++  +GL+RF T  Y  P   NL  I MHLTNYS+N HS NF  S  A
Sbjct: 391 YVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGNFIHSDSA 450

Query: 328 HSGSKRKLSTFSAYLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNSA 387
            +GSKR  S+    L     +++++W DI  V+IKT+I+  P ++  Y +  P       
Sbjct: 451 STGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGRPGPT 510

Query: 388 CFEILGFDILLDHKLKPWLLEVNHSPSF--------------STDSRLDKEVKDGLLYDT 433
           CF+ILGFDILL   LKP LLEVN +PS               +  S +D+EVK  ++ DT
Sbjct: 511 CFQILGFDILLMKNLKPILLEVNANPSMRIEHEHELSPGVFENVPSLVDEEVKVAVIRDT 570

Query: 434 LVLIN 438
           L L++
Sbjct: 571 LRLMD 575


>gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo
           sapiens]
          Length = 1281

 Score =  213 bits (541), Expect = 8e-55
 Identities = 124/325 (38%), Positives = 184/325 (56%), Gaps = 14/325 (4%)

Query: 121 VRRAAQQYGFRE-GGEDDDWTLYWTDYSVSLERVMEMKSYQKINHFPGMSEICRKDLLAR 179
           VR     +GF E      D+ L WT   +    +  +   QK+NHFP   E+ RKD L +
Sbjct: 77  VRSILTAHGFHEVHPSSTDYNLMWTGSHLKPFLLRTLSEAQKVNHFPRSYELTRKDRLYK 136

Query: 180 NMSRMLKMFP-KDFRFFPRTWCLPADWGDL-QTYSRSRKNKTYICKPDSGCQGKGIFITR 237
           N+ RM      K F   P+T+ LPA++ +   +YS+ R    +I KP +  +G+G+++  
Sbjct: 137 NIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYSKDRG--PWIVKPVASSRGRGVYLIN 194

Query: 238 TVKEIKPGEDMICQLYISKPFIIDGFKFDLRIYVLVTSCDPLRIFVYNEGLARFATTSYS 297
              +I   E+++   YI+ P +ID FKFD+R+YVLVTS DPL I++Y EGLARFAT  Y 
Sbjct: 195 NPNQISLEENILVSRYINNPLLIDDFKFDVRLYVLVTSYDPLVIYLYEEGLARFATVRYD 254

Query: 298 RPCTDNLDDICMHLTNYSINKHSSNF-----SRDAHSGSKRKLSTFSAYLEDHSYNVEQI 352
           +    N+ +  MHLTNYS+NK S ++           G+K  +S    YL+    +   +
Sbjct: 255 QG-AKNIRNQFMHLTNYSVNKKSGDYVSCDDPEVEDYGNKWSMSAMLRYLKQEGRDTTAL 313

Query: 353 WRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNSACFEILGFDILLDHKLKPWLLEVNHS 412
              +ED+IIKT+ISA   I     T  P+    S+CFE+ GFD+L+D  LKPWLLEVN S
Sbjct: 314 MAHVEDLIIKTIISAELAIATACKTFVPH---RSSCFELYGFDVLIDSTLKPWLLEVNLS 370

Query: 413 PSFSTDSRLDKEVKDGLLYDTLVLI 437
           PS + D+ LD ++K  ++ D   ++
Sbjct: 371 PSLACDAPLDLKIKASMISDMFTVV 395


>gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo
           sapiens]
          Length = 592

 Score =  194 bits (493), Expect = 3e-49
 Identities = 133/410 (32%), Positives = 202/410 (49%), Gaps = 46/410 (11%)

Query: 137 DDWTLYWTDYSVSLERVMEMKSYQKINHFPGMSEICRKDLLARNMSRMLKMFPKD-FRFF 195
           +DW LYW   S  +     +K +Q++NH PG +++ RKD LA+++  M +M+    ++F 
Sbjct: 119 EDWNLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFI 178

Query: 196 PRTWCLPADWGD-LQTYSRSR-----KNKTYICKPDSGCQGKGIFITRTVKEIKPGEDMI 249
           P T+ +P D+   +  Y + R     K+  +ICKP    +G+GI I    K+    +  I
Sbjct: 179 PLTFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELSRGRGILIFSDFKDFIFDDMYI 238

Query: 250 CQLYISKPFIIDGFKFDLRIYVLVTSCDPLRIFVYNEGLARFATTSYSRPCTDNLDDICM 309
            Q YIS P +I  +K DLRIYV VT   PL I+VY EGL RFAT  +      NL +   
Sbjct: 239 VQKYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFD---LSNLQNNYA 295

Query: 310 HLTNYSINKHSSNFSRDAH---SGSKRKLSTFSAYLEDHSYNVEQIWRDIEDVIIKTLIS 366
           HLTN SINK  +++ +       G K  LS F +YL     +   +W+ I  ++I T+++
Sbjct: 296 HLTNSSINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMVILTILA 355

Query: 367 AHPIIRHNYHTCFPNHTLNSACFEILGFDILLDHKLKPWLLEVNHSPSFSTDSRLDKEVK 426
             P +              + CFE+ GFDIL+D  LKPWLLEVN+SP+ + D   D  VK
Sbjct: 356 IAPSV-----------PFAANCFELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVK 404

Query: 427 DGLLYDTLVLINLESCDKKKVLEEERQRGQFLQQCCSREMRIEEAKGFRAVQLKKTETYE 486
             L++D + LI L            R  G+           I+ AK  R          +
Sbjct: 405 RKLVHDIIDLIYLNGL---------RNEGREASNATHGNSNIDAAKSDRG-------GLD 448

Query: 487 KENCGGFRLIYPSLNSEKYEKFFQDNNSLFQNTVASRAREEYARQLIQEL 536
             +C    L Y SL+     + + +++S+ +  V+ R     A QL  E+
Sbjct: 449 APDC----LPYDSLSFT--SRMYNEDDSVVEKAVSVRPEAAPASQLEGEM 492


>gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo
           sapiens]
          Length = 423

 Score =  186 bits (471), Expect = 1e-46
 Identities = 114/346 (32%), Positives = 175/346 (50%), Gaps = 51/346 (14%)

Query: 126 QQYGFREGGEDDDWTLYWTDYSV-----SLERVMEMKSYQKINHFPGMSEICRKDLLARN 180
           ++ G+ +  E++DW  YW          S+E    +   Q +NHFP   E+ RKDL+ +N
Sbjct: 21  EKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQIVNHFPNHYELTRKDLMVKN 80

Query: 181 MSRMLKMFPKD---------------FRFFPRTWCLPADWGDLQTYSRSRKNKTYICKPD 225
           + R  K   K+                 F P T+ LPAD+       R   + T+I KP 
Sbjct: 81  IKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPC 140

Query: 226 SGCQGKGIFITRTVKEIKPG---------------EDMICQLYISKPFIIDGFKFDLRIY 270
              QGKGIF+   + +IK                 E  +  LYI+ P +I G KFDLR+Y
Sbjct: 141 GKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLIGGRKFDLRLY 200

Query: 271 VLVTSCDPLRIFVYNEGLARFATTSYSRPCTDNLDDICMHLTNYSINKHSSNFSRDAHSG 330
           VLV++  PLR ++Y  G  RF T  Y+ P T  LD++ +HLTN +I KH  +++     G
Sbjct: 201 VLVSTYRPLRCYMYKLGFCRFCTVKYT-PSTSELDNMFVHLTNVAIQKHGEDYNHI--HG 257

Query: 331 SKRKLSTFSAYLEDHSYN--VEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNSAC 388
            K  +S    YLE         +++ +I  +I+++L +  P++ ++ H           C
Sbjct: 258 GKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKH-----------C 306

Query: 389 FEILGFDILLDHKLKPWLLEVNHSPSFSTDSRLDKEVKDGLLYDTL 434
           FE  G+DI++D KLKPWL+EVN SPS ++ +  D+ +K  L+ DTL
Sbjct: 307 FECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTL 352


>gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Homo
           sapiens]
          Length = 538

 Score =  182 bits (462), Expect = 1e-45
 Identities = 94/244 (38%), Positives = 141/244 (57%), Gaps = 13/244 (5%)

Query: 161 KINHFPGMSEICRKDLLARNMSRMLKMFPKDFRFFPRTWCLPADWGDLQTYSRSRKNK-- 218
           ++N FPGM+E+ RK  L+R +  M  +FP+++ F+PR+W LP ++       +  K+   
Sbjct: 271 QVNKFPGMTEMVRKITLSRAVRTMQNLFPEEYNFYPRSWILPDEFQLFVAQVQMVKDDDP 330

Query: 219 ----TYICKPDSGCQGKGIFITRTVKEIK-----PGEDMICQLYISKPFIIDGFKFDLRI 269
               T+I KPD GCQG GI++ +   +I+          + Q YI KP +ID  KFD+R+
Sbjct: 331 SWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLLIDKLKFDIRL 390

Query: 270 YVLVTSCDPLRIFVYNEGLARFATTSYSRPCTDNLDDICMHLTNYSINKHSSNF--SRDA 327
           YVL+ S DPL I++  +GL+RF T  Y  P   NL  I MHLTNYS+N HS NF  S  A
Sbjct: 391 YVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGNFIHSDSA 450

Query: 328 HSGSKRKLSTFSAYLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNSA 387
            +GSKR  S+    L     +++++W DI  V+IKT+I+  P ++  Y +  P       
Sbjct: 451 STGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGRPGPT 510

Query: 388 CFEI 391
           CF++
Sbjct: 511 CFQV 514


>gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo
           sapiens]
          Length = 439

 Score =  158 bits (399), Expect = 2e-38
 Identities = 120/382 (31%), Positives = 186/382 (48%), Gaps = 64/382 (16%)

Query: 93  LQNAQQQG----KKKRKKKRLVINLSSCRYESVRRAAQQY-GFREGGEDDDWTLYWTDYS 147
           LQN   +G    K K +++R  I   +    ++    +   G+ E  ++ +W  YW D S
Sbjct: 22  LQNQNYKGHGLSKGKEREQRASIRFKTTLMNTLMDVLRHRPGWVEVKDEGEWDFYWCDVS 81

Query: 148 VSLERVME--MKSYQKINHFPGMSEICRKDLLARNMSRMLKMFPKDFR--------FFPR 197
              E      M  + +I+HF    E+ RK+ + +N+ R  K   ++          FFP+
Sbjct: 82  WLRENFDHTYMDEHVRISHFRNHYELTRKNYMVKNLKRFRKQLEREAGKLEAAKCDFFPK 141

Query: 198 TWCLPADWGDLQTYSRSRKNKTYICKPDSGCQGKGIFITRTVKEIK-------------- 243
           T+ +P ++       R     T+I KP +  QGKGIF+ R +K+I               
Sbjct: 142 TFEMPCEYHLFVEEFRKNPGITWIMKPVARSQGKGIFLFRRLKDIVDWRKDTRSSDDQKD 201

Query: 244 --PGEDMICQLYISKPFIIDGFKFDLRIYVLVTSCDPLRIFVYNEGLARFATTSYSRPCT 301
             P E+ + Q YI  P++I G KFDLR+YVLV S       V+ E L     + + R   
Sbjct: 202 DIPVENYVAQRYIENPYLIGGRKFDLRVYVLVMS-------VFAECL---LWSGHRR--- 248

Query: 302 DNLDDICMHLTNYSINKHSSNFSRDAHSGSKRKLSTFSAYL--EDHSYNVEQIWRDIEDV 359
               D+  HLTN ++ K S ++      G K  L  F  YL  +     VE ++RDI+++
Sbjct: 249 ---QDV--HLTNVAVQKTSPDY--HPKKGCKWTLQRFRQYLASKHGPEAVETLFRDIDNI 301

Query: 360 IIKTLISAHPIIRHNYHTCFPNHTLNSACFEILGFDILLDHKLKPWLLEVNHSPSFSTDS 419
            +K+L S   +I  + H           CFE+ G+DIL+D  LKPWLLEVN SPS +  S
Sbjct: 302 FVKSLQSVQKVIISDKH-----------CFELYGYDILIDQDLKPWLLEVNASPSLTASS 350

Query: 420 RLDKEVKDGLLYDTLVLINLES 441
           + D E+K  LL DTL ++++E+
Sbjct: 351 QEDYELKTCLLEDTLHVVDMEA 372


>gi|194239681 tubulin tyrosine ligase-like family, member 10 isoform
           1 [Homo sapiens]
          Length = 673

 Score = 97.8 bits (242), Expect = 4e-20
 Identities = 70/265 (26%), Positives = 118/265 (44%), Gaps = 29/265 (10%)

Query: 194 FFPRTWCLPADWGDLQTYSRSRKNKTYICKPDSGCQGKGIFITRTVKEI----------- 242
           FFP T+ L         ++   + + +ICKP +  QGKGIF+ R  +E+           
Sbjct: 284 FFPETYRLDLKHEREAFFTLFDETQIWICKPTASNQGKGIFLLRNQEEVAALQAKTRSME 343

Query: 243 ----------KPGEDMICQLYISKPFIIDGFKFDLRIYVLVTSCDPLRIFVYNEGLARFA 292
                     +  +  + Q YI  P ++DG KFD+R Y+L+    P  IF +  G AR  
Sbjct: 344 DDPIHHKTPFRGPQARVVQRYIQNPLLVDGRKFDVRSYLLIACTTPYMIF-FGHGYARLT 402

Query: 293 TTSYSRPCTDNLDDICMHLTNYSINKHSSNFSRDAHSGSKRKLSTFSAYLEDHSYNVEQI 352
            + Y      +  D+  HLTN  + K S  +       +   +   + Y+ D  +    +
Sbjct: 403 LSLYD----PHSSDLGGHLTNQFMQKKSPLYML-LKEHTVWSMEHLNRYISDTFWKARGL 457

Query: 353 WRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNSACFEILGFDILLDHKLKPWLLEVNHS 412
            +D     +K  +    I+ H +    P        F+++G D L+D   K WLLE+N +
Sbjct: 458 AKDWVFTTLKKRMQQ--IMAHCFLAAKPKLDCKLGYFDLIGCDFLIDDNFKVWLLEMNSN 515

Query: 413 PSFSTDSRLDKEVKDGLLYDTLVLI 437
           P+  T+  + KEV  G++ +TL L+
Sbjct: 516 PALHTNCEVLKEVIPGVVIETLDLV 540


>gi|24308516 tubulin tyrosine ligase [Homo sapiens]
          Length = 377

 Score = 96.7 bits (239), Expect = 9e-20
 Identities = 79/292 (27%), Positives = 132/292 (45%), Gaps = 51/292 (17%)

Query: 160 QKINHFPGMSEICRKDLLAR------NMSRMLKMFPKDFRFFP---RTWCLPADWGD--- 207
           Q +N++ G  ++CRK  L +       ++     FP+ +  +P   +T   PA  G    
Sbjct: 60  QLVNYYRGADKLCRKASLVKLIKTSPELAESCTWFPESYVIYPTNLKTPVAPAQNGIQPP 119

Query: 208 ------------LQTYSRSRKN---KTYICKPDSGCQGKGIFITRTVKEI-----KPGED 247
                       L +Y+R +++     +I K  +G +G+GI I+    E+       G+ 
Sbjct: 120 ISNSRTDEREFFLASYNRKKEDGEGNVWIAKSSAGAKGEGILISSEASELLDFIDNQGQV 179

Query: 248 MICQLYISKPFIIDGF--KFDLRIYVLVTSCDPLRIFVYNEGLARFATTSYSRPCTDNLD 305
            + Q Y+  P +++    KFD+R +VLV       I++Y EG+ R A+  Y     DN  
Sbjct: 180 HVIQKYLEHPLLLEPGHRKFDIRSWVLVDH--QYNIYLYREGVLRTASEPYH---VDNFQ 234

Query: 306 DICMHLTNYSINKHSSNFSRDAHSGSKRKLSTFSAYLEDHSYNV---EQIWRDIEDVIIK 362
           D   HLTN+ I K  S        G++     F+ YL   + N+     I   I+ +I  
Sbjct: 235 DKTCHLTNHCIQKEYSKNYGKYEEGNEMFFKEFNQYLTS-ALNITLESSILLQIKHIIRN 293

Query: 363 TLISAHPIIRHNYHTCFPNHTLNSACFEILGFDILLDHKLKPWLLEVNHSPS 414
            L+S  P I   +        L    F++ GFD ++D +LK WL+EVN +P+
Sbjct: 294 CLLSVEPAISTKH--------LPYQSFQLFGFDFMVDEELKVWLIEVNGAPA 337


>gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo
           sapiens]
          Length = 772

 Score = 84.3 bits (207), Expect = 4e-16
 Identities = 67/236 (28%), Positives = 107/236 (45%), Gaps = 35/236 (14%)

Query: 220 YICKPDSGCQGKGIFITRTVKEI-----------KPGEDMICQLYISKPFIIDGFKFDLR 268
           +I KP +  +G+GI     ++E+           K G+  + Q YI +P +I G KFDLR
Sbjct: 280 WIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPVVMKDGK-WVVQKYIERPLLIFGTKFDLR 338

Query: 269 IYVLVTSCDPLRIFVYNEGLARFATTSYSRPCTDNLDDICMHLTNYSINKHSSN------ 322
            + LVT  +PL ++ Y +   RF+T  +S    DN     +HL N SI KH  N      
Sbjct: 339 QWFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNLDN----SVHLCNNSIQKHLENSCHRHP 394

Query: 323 -FSRDAHSGSKRKLSTFSAYLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPN 381
               D    S+R    F A+L++        W     +I+  +  A   + H   T    
Sbjct: 395 LLPPDNMWSSQR----FQAHLQE--MGAPNAW---STIIVPGMKDA---VIHALQTSQDT 442

Query: 382 HTLNSACFEILGFDILLDHKLKPWLLEVNHSPSFSTDSRLDKEVKDGLLYDTLVLI 437
                A FE+ G D +     +PWL+E+N SP+ +  + +   +  G+  DTL ++
Sbjct: 443 VQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVV 498


>gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo
           sapiens]
          Length = 834

 Score = 70.5 bits (171), Expect = 7e-12
 Identities = 56/198 (28%), Positives = 88/198 (44%), Gaps = 15/198 (7%)

Query: 249 ICQLYISKPFIIDGFKFDLRIYVLVTSCDPLRIFVYNEGLARFATTSYSRPCTDNLDDIC 308
           + Q YI  P +I   KFD+R + LVT  +PL I+ Y E   RF+T  +S    D LD   
Sbjct: 374 VVQKYIETPLLICDTKFDIRQWFLVTDWNPLTIWFYKESYLRFSTQRFS---LDKLDS-A 429

Query: 309 MHLTNYSINKHSSNFSRDAHSGSKRKLST---FSAYLEDHSYNVEQIWRDIEDVIIKTLI 365
           +HL N ++ K+  N    +       + T   F  YL+        +W     VI  ++ 
Sbjct: 430 IHLCNNAVQKYLKNDVGRSPLLPAHNMWTSTRFQEYLQRQGRGA--VW---GSVIYPSMK 484

Query: 366 SAHPIIRHNYHTCFPNHTLNSACFEILGFDILLDHKLKPWLLEVNHSPSFSTDSRLDKEV 425
            A   I H       +       FE+ G D +L    +PWL+E+N SP+    + +  ++
Sbjct: 485 KA---IAHAMKVAQDHVEPRKNSFELYGADFVLGRDFRPWLIEINSSPTMHPSTPVTAQL 541

Query: 426 KDGLLYDTLVLINLESCD 443
              +  DT+ +    SCD
Sbjct: 542 CAQVQEDTIKVAVDRSCD 559


>gi|194239678 tubulin tyrosine ligase-like family, member 10 isoform
           2 [Homo sapiens]
          Length = 404

 Score = 63.9 bits (154), Expect = 6e-10
 Identities = 43/148 (29%), Positives = 66/148 (44%), Gaps = 26/148 (17%)

Query: 194 FFPRTWCLPADWGDLQTYSRSRKNKTYICKPDSGCQGKGIFITRTVKEI----------- 242
           FFP T+ L         ++   + + +ICKP +  QGKGIF+ R  +E+           
Sbjct: 211 FFPETYRLDLKHEREAFFTLFDETQIWICKPTASNQGKGIFLLRNQEEVAALQAKTRSME 270

Query: 243 ----------KPGEDMICQLYISKPFIIDGFKFDLRIYVLVTSCDPLRIFVYNEGLARFA 292
                     +  +  + Q YI  P ++DG KFD+R Y+L+    P  IF +  G AR  
Sbjct: 271 DDPIHHKTPFRGPQARVVQRYIQNPLLVDGRKFDVRSYLLIACTTPYMIF-FGHGYARLT 329

Query: 293 TTSYSRPCTDNLDDICMHLTNYSINKHS 320
            + Y      +  D+  HLTN  + K S
Sbjct: 330 LSLYD----PHSSDLGGHLTNQFMQKKS 353


>gi|11056036 tubulin tyrosine ligase-like family, member 12 [Homo
           sapiens]
          Length = 644

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 44/163 (26%), Positives = 76/163 (46%), Gaps = 17/163 (10%)

Query: 162 INHFPGMSEICRKDLLARNMSRMLKMFPKDFRFFPRTWCLPADWGDLQTYSRSRK----N 217
           +N FP  + +  KD LA    R     P+   + PRT+ L  +     +Y + R+    +
Sbjct: 356 LNQFPCENLLTVKDCLASIARRAGG--PEGPPWLPRTFNLRTELPQFVSYFQQRERWGED 413

Query: 218 KTYICKPDSGCQGKGIFITRTVKEI---KPGEDMICQLYISKPFI-----IDGFKFDLRI 269
             +ICKP +  +     +T+++  I   +     +   YI  P +     +   KFD+R 
Sbjct: 414 NHWICKPWNLARSLDTHVTKSLHSIIRHRESTPKVVSKYIESPVLFLREDVGKVKFDIRY 473

Query: 270 YVLVTSCDPLRIFVYNEGLARFATTSYSRPCTDNLDDICMHLT 312
            VL+ S  PLR+FVY+    RF+  +++    ++LDD   H T
Sbjct: 474 IVLLRSVRPLRLFVYDVFWLRFSNRAFA---LNDLDDYEKHFT 513


>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
          Length = 1213

 Score = 40.8 bits (94), Expect = 0.006
 Identities = 76/358 (21%), Positives = 139/358 (38%), Gaps = 46/358 (12%)

Query: 440  ESCDKKKVLEEERQRGQFLQQCCSREMRIEEAKGFRAVQLKKTETYEKENCGGFRLIYPS 499
            E  +K+  L + +     LQQ    E    +  G   + L K     K      R + PS
Sbjct: 733  ELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKELELSKRYS---RALRPS 789

Query: 500  LNSEKYEKFFQDNNSLFQNTVASRAREE-----YARQLIQE-------LRLKREKKPFQM 547
            +N  +       +  +  + V+  A EE     + R+  QE       LR    KKP + 
Sbjct: 790  VNGRRMVDVPVTSTGVQTDAVSGEAAEEETPAVFIRKSFQEENHIMSNLRQVGLKKPVER 849

Query: 548  KKKVEMQGESAGEQVRKKGMRGWQQKQQ------QKDKAATQASKQYIQPLTL-VSYTPD 600
               ++    +A E   +K    W +K++      Q+    T +S  +   + L       
Sbjct: 850  SSVLDRYPPAANELTMRKSWIPWMRKRENGPSITQEKGPRTNSSPGHPGEVVLSPKQGQP 909

Query: 601  LLLSVRGERKNETDSSLNQEAPTEE----ASSVFPKLTSAKPFSSLPDLRNINLSSSKLE 656
            L + V  + +N T ++L   +PT E    +++V P L + KP  ++  + + N+   K +
Sbjct: 910  LHIRVTPDHENST-ATLEITSPTSEEFFSSTTVIPTLGNQKPRITI--IPSPNVMPQKQK 966

Query: 657  PSKPNFSIKEAKSASAVNVFTGTVHLTSVETTPESTTQLSISPKSPPTLAVTASSEYSGP 716
                    + A S   +  F       S E TPES         + P   +T S+  +  
Sbjct: 967  SGDTTLGPERAMSPVTITTF-------SREKTPESGRGAFADRPTSPIQIMTVSTSAAPA 1019

Query: 717  ETDRVVSFKCKKQQTPPHLTQKKML--KSFLPTKSKSFWESPNTNWTLLKSDMNKPHL 772
            E    ++   + Q+ P   T  K+   K  +PT  + +    N+N  ++ ++ NK H+
Sbjct: 1020 E----IAVSPESQEMPMGRTILKVTPEKQTVPTPVRKY----NSNANIITTEDNKIHI 1069


>gi|117190342 PHD finger protein 2 [Homo sapiens]
          Length = 1096

 Score = 40.0 bits (92), Expect = 0.010
 Identities = 46/182 (25%), Positives = 77/182 (42%), Gaps = 27/182 (14%)

Query: 555  GESAGEQVRKKGMRG------WQQKQQQKDKAATQASKQYIQPLTLVSYTPDLLLSVRGE 608
            G+SAG+++ K+  +       ++++Q   D  A      Y+ P +L S   + +   R +
Sbjct: 838  GKSAGKRLLKRAAKNSVDLDDYEEEQDHLD--ACFKDSDYVYP-SLESDEDNPIFKSRSK 894

Query: 609  RKNETDSSLNQEAPTEEASSVFPKLTSA-KPFSSLPDLRNIN---------LSSSKLEPS 658
            ++  +D     +AP    + V P +    +P      + +I          LS  + + S
Sbjct: 895  KRKGSD-----DAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKS 949

Query: 659  KPNFSIKEAKSASAVNVFTGT---VHLTSVETTPESTTQLSISPKSPPTLAVTASSEYSG 715
            K   S K   + +  +  T T      TS  TTP STT  S +P S  T +  AS E S 
Sbjct: 950  KKKKSAKRKLTPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSS 1009

Query: 716  PE 717
            PE
Sbjct: 1010 PE 1011


>gi|46399200 testis-specific bromodomain protein [Homo sapiens]
          Length = 947

 Score = 37.4 bits (85), Expect = 0.063
 Identities = 57/231 (24%), Positives = 101/231 (43%), Gaps = 39/231 (16%)

Query: 646 RNINLSSSKLEPSKPNFSIKEAKSASAVNVFTGT-------VHLTSVETTPESTTQLSIS 698
           +NI +SS+K E S P+ + K  K     +VF  T       V   SV ++ ++  Q++  
Sbjct: 152 QNIAVSSAK-EKSSPSATEKVFKQQEIPSVFPKTSISPLNVVQGASVNSSSQTAAQVTKG 210

Query: 699 PK------SPPTLAVTASSEYSGPETDRVVSFKCKKQQTPPHLTQKKMLKSFLPTKSKSF 752
            K      +P T AV ASSE+S   T++ V+        PP   ++ M K+ LP   + +
Sbjct: 211 VKRKADTTTPATSAVKASSEFSPTFTEKSVAL-------PP--IKENMPKNVLPDSQQQY 261

Query: 753 WESPNTNWTLLKSDMNKPHLISELLTKLQLSGKLSFFPAHYNP----KLGMNN---LSQN 805
               N   T+  ++  +    SE+L ++      S+    YNP     LG++N   + +N
Sbjct: 262 ----NVVKTVKVTEQLRH--CSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKN 315

Query: 806 PSLPGECHSRSDSSGEKRQLDVSS---LLLQSPQSYNVTLRDLLVIATPAQ 853
           P   G    + D+   K     ++   L+  +   YN    +++ +A   Q
Sbjct: 316 PMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQ 366



 Score = 34.3 bits (77), Expect = 0.53
 Identities = 34/155 (21%), Positives = 65/155 (41%), Gaps = 13/155 (8%)

Query: 498 PSLNSEKYEKFFQDNNSLFQNTVASRAREEYARQLIQELRLKREKKPFQMKKKVEMQGES 557
           PSL++   ++   D  +L  +T+  R  E+Y    +++  LK   K   M K+ E+  + 
Sbjct: 542 PSLSNSNPDEIEIDFETLKASTL--RELEKYVSACLRKRPLKPPAKKIMMSKE-ELHSQK 598

Query: 558 AGEQVRK----KGMRGWQQKQQQKDKAATQASKQYIQPLTLVSYTPDLLLSVRGERKNET 613
             E  ++          +++Q + DK     + + +  L+  S +     S        +
Sbjct: 599 KQELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSS-----SSSSSESESS 653

Query: 614 DSSLNQEAPTEEASSVFPKLTSAKPFSSLPDLRNI 648
            S L+    ++  S +FPK T  KP  S P   N+
Sbjct: 654 SSDLSSSDSSDSESEMFPKFTEVKPNDS-PSKENV 687


>gi|46399198 testis-specific bromodomain protein [Homo sapiens]
          Length = 947

 Score = 37.4 bits (85), Expect = 0.063
 Identities = 57/231 (24%), Positives = 101/231 (43%), Gaps = 39/231 (16%)

Query: 646 RNINLSSSKLEPSKPNFSIKEAKSASAVNVFTGT-------VHLTSVETTPESTTQLSIS 698
           +NI +SS+K E S P+ + K  K     +VF  T       V   SV ++ ++  Q++  
Sbjct: 152 QNIAVSSAK-EKSSPSATEKVFKQQEIPSVFPKTSISPLNVVQGASVNSSSQTAAQVTKG 210

Query: 699 PK------SPPTLAVTASSEYSGPETDRVVSFKCKKQQTPPHLTQKKMLKSFLPTKSKSF 752
            K      +P T AV ASSE+S   T++ V+        PP   ++ M K+ LP   + +
Sbjct: 211 VKRKADTTTPATSAVKASSEFSPTFTEKSVAL-------PP--IKENMPKNVLPDSQQQY 261

Query: 753 WESPNTNWTLLKSDMNKPHLISELLTKLQLSGKLSFFPAHYNP----KLGMNN---LSQN 805
               N   T+  ++  +    SE+L ++      S+    YNP     LG++N   + +N
Sbjct: 262 ----NVVKTVKVTEQLRH--CSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKN 315

Query: 806 PSLPGECHSRSDSSGEKRQLDVSS---LLLQSPQSYNVTLRDLLVIATPAQ 853
           P   G    + D+   K     ++   L+  +   YN    +++ +A   Q
Sbjct: 316 PMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQ 366



 Score = 34.3 bits (77), Expect = 0.53
 Identities = 34/155 (21%), Positives = 65/155 (41%), Gaps = 13/155 (8%)

Query: 498 PSLNSEKYEKFFQDNNSLFQNTVASRAREEYARQLIQELRLKREKKPFQMKKKVEMQGES 557
           PSL++   ++   D  +L  +T+  R  E+Y    +++  LK   K   M K+ E+  + 
Sbjct: 542 PSLSNSNPDEIEIDFETLKASTL--RELEKYVSACLRKRPLKPPAKKIMMSKE-ELHSQK 598

Query: 558 AGEQVRK----KGMRGWQQKQQQKDKAATQASKQYIQPLTLVSYTPDLLLSVRGERKNET 613
             E  ++          +++Q + DK     + + +  L+  S +     S        +
Sbjct: 599 KQELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSS-----SSSSSESESS 653

Query: 614 DSSLNQEAPTEEASSVFPKLTSAKPFSSLPDLRNI 648
            S L+    ++  S +FPK T  KP  S P   N+
Sbjct: 654 SSDLSSSDSSDSESEMFPKFTEVKPNDS-PSKENV 687


>gi|149773468 RAD51 associated protein 2 [Homo sapiens]
          Length = 1159

 Score = 37.0 bits (84), Expect = 0.082
 Identities = 55/254 (21%), Positives = 96/254 (37%), Gaps = 51/254 (20%)

Query: 314 YSINKHSSNFSRDAHSGSKRKLSTFSAYLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRH 373
           Y +N HS + + +   G   K+S F           E I+ D+ +V  + + ++H II +
Sbjct: 754 YEVNMHSQDLNMERKQGHN-KISNFDC---------EHIFEDLCNVRQQAIPASHNIIHN 803

Query: 374 NY-HTCFPNHTLNS----ACFEILGFDILLDHKLKPWLLEVNHSPSFSTDSRLDKEVKDG 428
              HT      LN     +  E   +D++L  ++K     + +S     D++++KE KD 
Sbjct: 804 EETHTTSITQVLNFWNLLSEIEEKKYDLILKEEVKVTAESLTNSCQVHKDTKIEKEEKDS 863

Query: 429 LL-YDTLVLINLESCDKKKVLEEERQRGQFLQQCCSREMRIEEAKGFRAVQLKKTETYEK 487
               D +  +   S                     S+E+ +EE K      +  T  YE 
Sbjct: 864 FFPMDDMFSVQSVS-------------------LISKEVNVEENKYVNQNYVTNTNEYES 904

Query: 488 ENCGGFRLIYPSLNSEKYEKFFQDNNS-LFQNTVASRAREEYARQLIQELRLKREK---- 542
                   I P       + F + N+S L+ N        E   +  Q+L  K       
Sbjct: 905 --------ILPEREIANSKDFHRKNDSALYINHQFETGLSEGNDECFQDLAAKYLSTEAL 956

Query: 543 ---KPFQMKKKVEM 553
              K F+MK+K ++
Sbjct: 957 TIVKDFEMKRKFDL 970


>gi|53829376 plakophilin 4 isoform b [Homo sapiens]
          Length = 1149

 Score = 36.2 bits (82), Expect = 0.14
 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 8/105 (7%)

Query: 622 PTEEASSVFPKLTSAKPFSSLPD----LRNINLSSSKLEPSKPNFSIKEAKSASAVNVFT 677
           P+  +S+  P   +A P+S  P     +R I   +S+ + S PN    + ++ + V    
Sbjct: 258 PSAYSSTTLPAARAASPYSQRPASPTAIRRIGSVTSR-QTSNPNGPTPQYQTTARVG--- 313

Query: 678 GTVHLTSVETTPESTTQLSISPKSPPTLAVTASSEYSGPETDRVV 722
             + LT  +T   S +Q  +   SP    +TA  ++ GP   R V
Sbjct: 314 SPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTV 358


>gi|53829374 plakophilin 4 isoform a [Homo sapiens]
          Length = 1192

 Score = 36.2 bits (82), Expect = 0.14
 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 8/105 (7%)

Query: 622 PTEEASSVFPKLTSAKPFSSLPD----LRNINLSSSKLEPSKPNFSIKEAKSASAVNVFT 677
           P+  +S+  P   +A P+S  P     +R I   +S+ + S PN    + ++ + V    
Sbjct: 258 PSAYSSTTLPAARAASPYSQRPASPTAIRRIGSVTSR-QTSNPNGPTPQYQTTARVG--- 313

Query: 678 GTVHLTSVETTPESTTQLSISPKSPPTLAVTASSEYSGPETDRVV 722
             + LT  +T   S +Q  +   SP    +TA  ++ GP   R V
Sbjct: 314 SPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTV 358


>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
          Length = 1170

 Score = 36.2 bits (82), Expect = 0.14
 Identities = 38/150 (25%), Positives = 56/150 (37%), Gaps = 28/150 (18%)

Query: 607 GERKNETDSSLNQE-----APT----EEASSVFPKLTSAKPFSSLPD------------L 645
           G RK E    L Q+     AP     +E  ++ P  T+  P    P             +
Sbjct: 817 GARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTNGNPLLPFPGAQVRQNVKNRLLV 876

Query: 646 RNINLSSSKLEPSKPNFSIKEAKSASAVNVFTGTVHLTSVETTPESTTQ--LSISPKSPP 703
           +N ++S S ++P   NF    A             HL    T P+S TQ    + P  P 
Sbjct: 877 KNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQPLHKVLPIKPA 936

Query: 704 TLAVTASSEYSGPETDRVVSFKCKKQQTPP 733
            +      E + P+T RV S + + Q T P
Sbjct: 937 DV-----EEPAVPQTPRVASIQGRPQDTKP 961


>gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo
           sapiens]
          Length = 373

 Score = 36.2 bits (82), Expect = 0.14
 Identities = 37/171 (21%), Positives = 75/171 (43%), Gaps = 10/171 (5%)

Query: 466 MRIEEAKGFRAVQLKKTETYEKENCGGFRLIYPSLNSEKYEKFFQDNNSLFQNTVASRAR 525
           +R  E +G  + Q++     E++     ++  P      +E +F       ++ +  +A 
Sbjct: 110 LRGMELQGCASTQVESENNQEEQK----QVRLPESRLTPWEVWFIGKEKEERDRLQLKAL 165

Query: 526 EEYARQLIQELRLK-REKKPFQMKKKVEMQGESAGEQVRKKGMRGWQQKQQQKDKAATQA 584
           EE  +QL +   ++ REK+    ++K +   +   EQ RK+  R  +  ++ ++KAA + 
Sbjct: 166 EELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKE--REQKINKEMEEKAAKEL 223

Query: 585 SKQYIQPLTLVSYTPDLLLSVRGE---RKNETDSSLNQEAPTEEASSVFPK 632
            K+Y+Q      Y   L      E   +K E +    Q+A  +E   +  K
Sbjct: 224 EKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEK 274


>gi|120587019 zinc finger protein 318 [Homo sapiens]
          Length = 2279

 Score = 36.2 bits (82), Expect = 0.14
 Identities = 50/221 (22%), Positives = 82/221 (37%), Gaps = 33/221 (14%)

Query: 498  PSLNSEKYEKFFQDNNSLFQNTVASRAREEYARQLIQELRLKREKKPFQMKKKVEMQGES 557
            PSL     EK   + N   Q       RE+     ++  R  R+KK + ++ ++E   + 
Sbjct: 868  PSLIRYNPEKISDEKNRASQKQKVIEEREK-----LKNDREARQKKMYYLRTELERLHKQ 922

Query: 558  AGEQVRKKGMRGWQQKQQQKDKAATQASKQYIQPLTLVSYTPDLLLSVRGERKNETDSSL 617
             GE +RKK     ++K   KD             L  VS   D ++    E + E + + 
Sbjct: 923  QGEMLRKKR----REKDGHKDPL-----------LVEVSRLQDNIMKDIAELRQEAEEAE 967

Query: 618  NQEAPTEEASSVFPKLTSAKPFSSLPDLRNINLSSSKLEPSK-----PNFSIKEAKSASA 672
             +++  ++ + +       K   SL D R       K E SK      +FS   +   S 
Sbjct: 968  KKQSELDKVAQILGINIFDKSQKSLSDSREPTEKPGKAEKSKSPEKVSSFSNSSSNKESK 1027

Query: 673  VNVFTGTVHLTSVETTPESTTQLSISPKSPPTLAVTASSEY 713
            VN             +P+S T+    P        TA+ EY
Sbjct: 1028 VNNEKFRTKSPKPAESPQSATKQLDQP--------TAAYEY 1060


>gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]
          Length = 910

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 53/264 (20%), Positives = 98/264 (37%), Gaps = 53/264 (20%)

Query: 515 LFQNTVASRAREEYARQLIQELRLKREKKP-----FQMKKKVEMQGESAGEQVRKKGMRG 569
           L ++    RA EE  R L ++++  ++ K      F   K    + +  G  + +  MR 
Sbjct: 19  LQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHRDKIHGADIIRASMRK 78

Query: 570 WQQK---QQQKDKAATQASKQYIQPLTLVSYTPDLLLSVRGERKNETDSSLNQEAPTEEA 626
            + +   +Q KD+    A + ++  +   ++ P  L  V              E P E+A
Sbjct: 79  KRPQIAAEQSKDRE-NGAKESWVNNVNKDAFLPPELAGV-------------VEEPEEDA 124

Query: 627 SSVFPKLTSAKPFSSLPDLRNINLSSSKLEPSK-----------PNFSIKEAKSASAVNV 675
           +   P  +   P SS+ D+   N     + P K              S ++ K+  + N 
Sbjct: 125 APASPSSSVVNPASSVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQSKNG 184

Query: 676 FTGTVHLTSVETTPESTTQLSISPKSPPTLAVTASSEYSGPETDRVVSFKCKKQQTPPHL 735
            TG    +  +   ES        K   T+A T+  +              K +QT P L
Sbjct: 185 RTGLFQTSKEDELSES--------KEKSTVADTSIQKLE------------KSKQTLPGL 224

Query: 736 TQKKMLKSFLPTKSKSFWESPNTN 759
           +    +K+ +P   K  ++S + N
Sbjct: 225 SNGSQIKAPIPKARKMIYKSTDLN 248


>gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]
          Length = 934

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 53/264 (20%), Positives = 98/264 (37%), Gaps = 53/264 (20%)

Query: 515 LFQNTVASRAREEYARQLIQELRLKREKKP-----FQMKKKVEMQGESAGEQVRKKGMRG 569
           L ++    RA EE  R L ++++  ++ K      F   K    + +  G  + +  MR 
Sbjct: 19  LQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHRDKIHGADIIRASMRK 78

Query: 570 WQQK---QQQKDKAATQASKQYIQPLTLVSYTPDLLLSVRGERKNETDSSLNQEAPTEEA 626
            + +   +Q KD+    A + ++  +   ++ P  L  V              E P E+A
Sbjct: 79  KRPQIAAEQSKDRE-NGAKESWVNNVNKDAFLPPELAGV-------------VEEPEEDA 124

Query: 627 SSVFPKLTSAKPFSSLPDLRNINLSSSKLEPSK-----------PNFSIKEAKSASAVNV 675
           +   P  +   P SS+ D+   N     + P K              S ++ K+  + N 
Sbjct: 125 APASPSSSVVNPASSVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQSKNG 184

Query: 676 FTGTVHLTSVETTPESTTQLSISPKSPPTLAVTASSEYSGPETDRVVSFKCKKQQTPPHL 735
            TG    +  +   ES        K   T+A T+  +              K +QT P L
Sbjct: 185 RTGLFQTSKEDELSES--------KEKSTVADTSIQKLE------------KSKQTLPGL 224

Query: 736 TQKKMLKSFLPTKSKSFWESPNTN 759
           +    +K+ +P   K  ++S + N
Sbjct: 225 SNGSQIKAPIPKARKMIYKSTDLN 248


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 41/190 (21%), Positives = 83/190 (43%), Gaps = 17/190 (8%)

Query: 444  KKKVLEEERQRGQFLQQCCSREMRIEEAKGFRAVQLKKTETYEKENCGGFRLIYPSLNSE 503
            +++ L +ER+  Q  +Q   R+ R+EE K  R  Q +K    E E     +     L  E
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERK--FMEDEQQLRRQEGQQQLRQE 1616

Query: 504  KYEKFFQDNNSLFQNTVASRAREEYARQLI-QELRLKREKKPFQMK-------KKVEMQG 555
            +  KF +D   L +       R+E  R+ + +E +L+R+++  Q++       ++ E   
Sbjct: 1617 RDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLL 1676

Query: 556  ESAGEQVRKKGMRGWQQKQQQKDKAATQASKQYIQPLTLVSYTPDLLLSVRGERKNETDS 615
            +   EQ  ++  R  + +++++     +  ++++Q           L     ERK   + 
Sbjct: 1677 QEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ-------EEQQLRRQELERKFREEE 1729

Query: 616  SLNQEAPTEE 625
             L QE   E+
Sbjct: 1730 QLRQETEQEQ 1739



 Score = 34.3 bits (77), Expect = 0.53
 Identities = 38/181 (20%), Positives = 79/181 (43%), Gaps = 27/181 (14%)

Query: 449 EEERQRGQFLQQCCSREMRIEEAKGFRAVQLKKTET-----YEKENCGGFRLIY--PSLN 501
           EE+ QR +  QQ    E  ++E +  R  Q ++ +       E+E       +Y  P+L 
Sbjct: 837 EEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQ 896

Query: 502 SE--KYEKFFQDNNSLFQNTVASRAREEYARQLIQELRLKREKKPFQMKKKVEMQGESAG 559
            +  K ++  Q+              EE  R+  ++ R + +++ ++ +++++ + E   
Sbjct: 897 EQLRKEQQLLQEEE------------EELQREEREKRRRQEQERQYREEEQLQQEEEQLL 944

Query: 560 EQVRKKGMRGWQQKQQQKDKAATQASKQYIQPLTLVSYTPDLLLSVRGERKNETDSSLNQ 619
            + R+K  R  +++Q +KDK   Q  +Q      L+   P+       E+K   +  L Q
Sbjct: 945 REEREKRRRQERERQYRKDKKLQQKEEQ------LLGEEPEKRRRQEREKKYREEEELQQ 998

Query: 620 E 620
           E
Sbjct: 999 E 999



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 38/142 (26%), Positives = 69/142 (48%), Gaps = 20/142 (14%)

Query: 442 CDKKKVLEEERQRGQFLQQCCSREMRIEEAKGFRAVQLKKTETYEKENCGGFRLIYPSLN 501
           CD K+ L ++R++ +  ++   R+ ++EE  G R  Q  K +  E+E   G         
Sbjct: 103 CDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQ--KRQEQERELAEG------EEQ 154

Query: 502 SEKYEKFFQDNNSLFQNTVASRAREEYARQLIQELRLKR-EKKPFQMKKKVEMQGESAGE 560
           SEK E+  Q +    ++    R R+E+     QE   +R E++  Q  K  E +     E
Sbjct: 155 SEKQERLEQRDRQR-RDEELWRQRQEW-----QEREERRAEEEQLQSCKGHETEEFPDEE 208

Query: 561 QVRKKGM-----RGWQQKQQQK 577
           Q+R++ +     +G ++KQQQ+
Sbjct: 209 QLRRRELLELRRKGREEKQQQR 230



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 31/163 (19%), Positives = 80/163 (49%), Gaps = 30/163 (18%)

Query: 443  DKKKVLEEERQRGQFLQQCCSREMRIEEA-KGFRAVQLKKTETYEKENCGGFRLIYPSLN 501
            +++++  +ER+R +FLQ+   +++R +E  + FR  +  + ET +++             
Sbjct: 1696 EEQQLRRQERER-KFLQE--EQQLRRQELERKFREEEQLRQETEQEQ----------LRR 1742

Query: 502  SEKYEKFFQDNNSLFQNTVASRAREEYARQLIQELRLKREKKPFQM---------KKKVE 552
             E+Y K  ++     +       R+E  R+  +E +L++E++  Q+         +++ +
Sbjct: 1743 QERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQ 1802

Query: 553  MQGESAGEQVR---KKGMRGWQQKQ----QQKDKAATQASKQY 588
            ++ E   +Q+R   + G   W+++Q    +Q+ +   +  +QY
Sbjct: 1803 LRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQY 1845



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 32/144 (22%), Positives = 68/144 (47%), Gaps = 10/144 (6%)

Query: 444  KKKVLEEERQ-----RGQFLQQCCSREMRIEEAKGFRAVQLKKTETYEK-----ENCGGF 493
            ++K L+EE+Q     R Q L+Q   R+ R EE +  R  + +K    E+     E    F
Sbjct: 1389 ERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKF 1448

Query: 494  RLIYPSLNSEKYEKFFQDNNSLFQNTVASRAREEYARQLIQELRLKREKKPFQMKKKVEM 553
                  L  E++ KF ++   L +       R+E  R+ ++E +  R ++  +  ++ E+
Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQEL 1508

Query: 554  QGESAGEQVRKKGMRGWQQKQQQK 577
            + +    +  ++  +  +Q++Q+K
Sbjct: 1509 RSQEPERKFLEEEQQLHRQQRQRK 1532



 Score = 30.4 bits (67), Expect = 7.6
 Identities = 37/193 (19%), Positives = 79/193 (40%), Gaps = 34/193 (17%)

Query: 443  DKKKVLEEERQRGQFLQQCCSREMRIEEAKGFRAVQL--KKTETYEKENCGGFRLIYPSL 500
            +++++L EER++ +  ++   R+ R EE       QL  ++ ET  ++            
Sbjct: 1029 EEEQLLREEREKRRLQER--ERQYREEEELQQEEEQLLGEERETRRRQEL--------ER 1078

Query: 501  NSEKYEKFFQDNNSLFQNTVASRAREEYARQ-------------LIQELRLKREKKPFQM 547
               K E+  Q+   L +     R R+E  RQ             L++E R KR ++  + 
Sbjct: 1079 QYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELER 1138

Query: 548  KKKVEMQGESAGEQVRKKGMRGWQQKQQQKDKAATQASKQYIQPLTLVSYTPDLLLSVRG 607
            + + E + +   EQ+          +++ + +   +  +QY +   L      LL   + 
Sbjct: 1139 QYREEEEVQQEEEQL---------LREEPEKRRRQELERQYREEEELQQEEEQLLREEQE 1189

Query: 608  ERKNETDSSLNQE 620
            +R+ E +    +E
Sbjct: 1190 KRRQERERQYREE 1202



 Score = 30.0 bits (66), Expect = 10.0
 Identities = 38/189 (20%), Positives = 84/189 (44%), Gaps = 27/189 (14%)

Query: 445 KKVLEEERQRGQFLQQCCSREMRIEEAKGFRAVQLKKTETYEKENCGGFRLIYPSLNSEK 504
           K+  E ER   +  +Q   R+   EE +  R ++L++ E  E++     +L        +
Sbjct: 459 KREEETERHEQERRKQQLKRDQ--EEERRERWLKLEEEERREQQERREQQLRREQEERRE 516

Query: 505 YEKFFQDNNSLFQNTVAS-----RAREEYARQLI---QELRLKREKKPFQMKKKVEMQGE 556
                Q+     Q  + S     R +EE   QL+   +E RL++E++  ++K++ E + +
Sbjct: 517 QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRD 576

Query: 557 SAGEQVRKKGMRGWQQKQQQKDKAATQASKQYIQPLTLVSYTPDLLLSVRGERKNETDSS 616
              +  R++  R  + K++Q+++   +  ++ ++ L               E++   +  
Sbjct: 577 QLLK--REEERRQQRLKREQEERLEQRLKREEVERL---------------EQEERREQR 619

Query: 617 LNQEAPTEE 625
           L +E P EE
Sbjct: 620 LKREEPEEE 628


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,482,669
Number of Sequences: 37866
Number of extensions: 1679553
Number of successful extensions: 7599
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 184
Number of HSP's that attempted gapping in prelim test: 6999
Number of HSP's gapped (non-prelim): 826
length of query: 891
length of database: 18,247,518
effective HSP length: 111
effective length of query: 780
effective length of database: 14,044,392
effective search space: 10954625760
effective search space used: 10954625760
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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