BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|195947374 claudin 5 [Homo sapiens] (303 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|195947374 claudin 5 [Homo sapiens] 623 e-179 gi|195947372 claudin 5 [Homo sapiens] 623 e-179 gi|11141861 claudin 9 [Homo sapiens] 243 2e-64 gi|153792768 claudin 6 [Homo sapiens] 240 1e-63 gi|4502875 claudin 3 [Homo sapiens] 238 5e-63 gi|4502877 claudin 4 [Homo sapiens] 227 1e-59 gi|10863887 claudin 1 [Homo sapiens] 198 4e-51 gi|153792186 claudin 7 [Homo sapiens] 194 6e-50 gi|183979973 claudin 19 isoform a [Homo sapiens] 187 1e-47 gi|183979975 claudin 19 isoform b [Homo sapiens] 187 1e-47 gi|40788011 claudin 8 [Homo sapiens] 186 3e-47 gi|6912316 claudin 17 [Homo sapiens] 167 1e-41 gi|225703142 claudin 14 [Homo sapiens] 166 2e-41 gi|21536294 claudin 14 [Homo sapiens] 166 2e-41 gi|225703138 claudin 14 [Homo sapiens] 166 2e-41 gi|6912314 claudin 14 [Homo sapiens] 166 2e-41 gi|225703140 claudin 14 [Homo sapiens] 166 2e-41 gi|9966781 claudin 2 [Homo sapiens] 149 2e-36 gi|5921465 claudin 10 isoform b [Homo sapiens] 137 1e-32 gi|47716519 claudin 20 [Homo sapiens] 133 2e-31 gi|7656981 claudin 15 [Homo sapiens] 133 2e-31 gi|33598916 claudin 10 isoform a [Homo sapiens] 122 3e-28 gi|169166402 PREDICTED: claudin-24-like [Homo sapiens] 119 4e-27 gi|7705961 claudin 18 isoform 1 [Homo sapiens] 118 7e-27 gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] 117 1e-26 gi|169166931 PREDICTED: claudin-24-like [Homo sapiens] 117 1e-26 gi|50345279 claudin 18 isoform 2 [Homo sapiens] 115 4e-26 gi|162417973 claudin 22 [Homo sapiens] 113 2e-25 gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] 105 4e-23 gi|157820127 claudin-like [Homo sapiens] 103 1e-22 >gi|195947374 claudin 5 [Homo sapiens] Length = 303 Score = 623 bits (1606), Expect = e-179 Identities = 303/303 (100%), Positives = 303/303 (100%) Query: 1 MTRARIGCFGPGGRARGTESAPEPSKRVPPGRSWQTQEVRQTRGANGLGPRAGSAGAKAP 60 MTRARIGCFGPGGRARGTESAPEPSKRVPPGRSWQTQEVRQTRGANGLGPRAGSAGAKAP Sbjct: 1 MTRARIGCFGPGGRARGTESAPEPSKRVPPGRSWQTQEVRQTRGANGLGPRAGSAGAKAP 60 Query: 61 GPAQGAAQHGLGGSAGLRVRVSPLAMGSAALEILGLVLCLVGWGGLILACGLPMWQVTAF 120 GPAQGAAQHGLGGSAGLRVRVSPLAMGSAALEILGLVLCLVGWGGLILACGLPMWQVTAF Sbjct: 61 GPAQGAAQHGLGGSAGLRVRVSPLAMGSAALEILGLVLCLVGWGGLILACGLPMWQVTAF 120 Query: 121 LDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVAL 180 LDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVAL Sbjct: 121 LDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVAL 180 Query: 181 FVTLAGAQCTTCVAPGPAKARVALTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVS 240 FVTLAGAQCTTCVAPGPAKARVALTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVS Sbjct: 181 FVTLAGAQCTTCVAPGPAKARVALTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVS 240 Query: 241 QKYELGAALYIGWAATALLMVGGCLLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKK 300 QKYELGAALYIGWAATALLMVGGCLLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKK Sbjct: 241 QKYELGAALYIGWAATALLMVGGCLLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKK 300 Query: 301 NYV 303 NYV Sbjct: 301 NYV 303 >gi|195947372 claudin 5 [Homo sapiens] Length = 303 Score = 623 bits (1606), Expect = e-179 Identities = 303/303 (100%), Positives = 303/303 (100%) Query: 1 MTRARIGCFGPGGRARGTESAPEPSKRVPPGRSWQTQEVRQTRGANGLGPRAGSAGAKAP 60 MTRARIGCFGPGGRARGTESAPEPSKRVPPGRSWQTQEVRQTRGANGLGPRAGSAGAKAP Sbjct: 1 MTRARIGCFGPGGRARGTESAPEPSKRVPPGRSWQTQEVRQTRGANGLGPRAGSAGAKAP 60 Query: 61 GPAQGAAQHGLGGSAGLRVRVSPLAMGSAALEILGLVLCLVGWGGLILACGLPMWQVTAF 120 GPAQGAAQHGLGGSAGLRVRVSPLAMGSAALEILGLVLCLVGWGGLILACGLPMWQVTAF Sbjct: 61 GPAQGAAQHGLGGSAGLRVRVSPLAMGSAALEILGLVLCLVGWGGLILACGLPMWQVTAF 120 Query: 121 LDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVAL 180 LDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVAL Sbjct: 121 LDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVAL 180 Query: 181 FVTLAGAQCTTCVAPGPAKARVALTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVS 240 FVTLAGAQCTTCVAPGPAKARVALTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVS Sbjct: 181 FVTLAGAQCTTCVAPGPAKARVALTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVS 240 Query: 241 QKYELGAALYIGWAATALLMVGGCLLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKK 300 QKYELGAALYIGWAATALLMVGGCLLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKK Sbjct: 241 QKYELGAALYIGWAATALLMVGGCLLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKK 300 Query: 301 NYV 303 NYV Sbjct: 301 NYV 303 >gi|11141861 claudin 9 [Homo sapiens] Length = 217 Score = 243 bits (620), Expect = 2e-64 Identities = 121/222 (54%), Positives = 160/222 (72%), Gaps = 9/222 (4%) Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145 M S LE+LG+ L ++GW G +++C LP+W+VTAF+ ++IV AQ W+GLWMSCVVQSTG Sbjct: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60 Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205 MQCKVYDS+LAL ++QAARAL V A+LLA + L V + GAQCTTCV AKAR+ LT Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT 120 Query: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265 GV+ L G+L L+P+CW A+ ++++FY+P V + K ELGA+LY+GWAA ALLM+GG L Sbjct: 121 AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL 180 Query: 266 LCCGAWVCTGRPDLSFP----VKYSAPRRPTATGDYDKKNYV 303 LCC C P + P + YS P R A+G DK++YV Sbjct: 181 LCC---TCP-PPQVERPRGPRLGYSIPSRSGASG-LDKRDYV 217 >gi|153792768 claudin 6 [Homo sapiens] Length = 220 Score = 240 bits (613), Expect = 1e-63 Identities = 116/220 (52%), Positives = 158/220 (71%), Gaps = 2/220 (0%) Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145 M SA ++ILG+VL L+GW +++C LPMW+VTAF+ ++IV AQ W+GLWMSCVVQSTG Sbjct: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60 Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205 MQCKVYDS+LAL ++QAARAL V A+L+A L V LAGA+CTTCV +KAR+ LT Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT 120 Query: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265 G++++ G+L L+P+CW A+ ++R+FY+P V +QK ELGA+LY+GWAA+ LL++GG L Sbjct: 121 SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL 180 Query: 266 LCCGAWVCTGRPDLSFPVKY--SAPRRPTATGDYDKKNYV 303 LCC + + +Y SAP +Y KNYV Sbjct: 181 LCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKNYV 220 >gi|4502875 claudin 3 [Homo sapiens] Length = 220 Score = 238 bits (607), Expect = 5e-63 Identities = 121/222 (54%), Positives = 153/222 (68%), Gaps = 9/222 (4%) Query: 88 SAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHM 147 S LEI G L ++GW G I+ C LPMW+V+AF+ NI+T+Q W+GLWM+CVVQSTG M Sbjct: 2 SMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQM 61 Query: 148 QCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALTGG 207 QCKVYDS+LAL ++QAARAL V A+LLA L V L GAQCT CV AKA++ + G Sbjct: 62 QCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAG 121 Query: 208 VLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCLLC 267 VL+L LL LVP+ W AN ++R+FY+P VP +QK E+GA LY+GWAA AL ++GG LLC Sbjct: 122 VLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC 181 Query: 268 CGAWVCTGRPD--LSFPVKYSAPRR--PTAT--GDYDKKNYV 303 C C R + V YSAPR P A+ YD+K+YV Sbjct: 182 CS---CPPREKKYTATKVVYSAPRSTGPGASLGTGYDRKDYV 220 >gi|4502877 claudin 4 [Homo sapiens] Length = 209 Score = 227 bits (578), Expect = 1e-59 Identities = 101/209 (48%), Positives = 150/209 (71%), Gaps = 3/209 (1%) Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145 M S L+++G+ L ++GW ++L C LPMW+VTAF+ NIVT+QT W+GLWM+CVVQSTG Sbjct: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60 Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205 MQCKVYDS+LAL ++QAARAL + ++++A + + +++ G +CT C+ AKA+ + Sbjct: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120 Query: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265 GV++L GL+ +VP+ W A+ ++++FY+P V QK E+GA+LY+GWAA+ LL++GG L Sbjct: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180 Query: 266 LCCGAWVCTGRPDLSFPVKYSAPRRPTAT 294 LCC C R D + KYSA R A+ Sbjct: 181 LCCN---CPPRTDKPYSAKYSAARSAAAS 206 >gi|10863887 claudin 1 [Homo sapiens] Length = 211 Score = 198 bits (504), Expect = 4e-51 Identities = 97/219 (44%), Positives = 138/219 (63%), Gaps = 9/219 (4%) Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145 M +A L++LG +L +GW G I++ LP W++ ++ NIVTAQ ++GLWMSCV QSTG Sbjct: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60 Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPA-KARVAL 204 +QCKV+DS+L LS+ +QA RAL V +LL +A+FV G +C C+ K R+A+ Sbjct: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120 Query: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264 GG ++L GL LV W+ N +V+EFYDP PV+ +YE G AL+ GWAA +L ++GG Sbjct: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180 Query: 265 LLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKKNYV 303 LLCC R S+P P+ ++G K+YV Sbjct: 181 LLCCSC----PRKTTSYPTPRPYPKPAPSSG----KDYV 211 >gi|153792186 claudin 7 [Homo sapiens] Length = 211 Score = 194 bits (494), Expect = 6e-50 Identities = 87/184 (47%), Positives = 128/184 (69%), Gaps = 1/184 (0%) Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145 M ++ L++LG + L+GW GL+ +P WQ++++ NI+TAQ +KGLWM CV QSTG Sbjct: 1 MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60 Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPA-KARVAL 204 M CK+YDSVLALS +QA RAL V +++L F+A+FV G +CT C KAR+A+ Sbjct: 61 MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120 Query: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264 GG++++ GL ALV W+ + +V +FY+P +P + KYE G A++IGWA +AL+++GG Sbjct: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180 Query: 265 LLCC 268 LL C Sbjct: 181 LLSC 184 >gi|183979973 claudin 19 isoform a [Homo sapiens] Length = 224 Score = 187 bits (475), Expect = 1e-47 Identities = 91/207 (43%), Positives = 131/207 (63%), Gaps = 7/207 (3%) Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145 M ++ L++LG L L GW G+I + LP W+ +++ I+TA ++GLWMSC QSTG Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGP-AKARVAL 204 +QCK+YDS+LAL +Q+ARAL V AVLL FVA+ +++ G +CT P AK RVA+ Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 Query: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264 GG L++ GL L + W+A +V +EF++PS PV+ +YE G AL++GWA+ L ++GG Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 Query: 265 LLCCGAWVCTGRPDLSFPVKYSAPRRP 291 LCC P+ P P RP Sbjct: 181 FLCCTC------PEPERPNSSPQPYRP 201 >gi|183979975 claudin 19 isoform b [Homo sapiens] Length = 211 Score = 187 bits (475), Expect = 1e-47 Identities = 91/207 (43%), Positives = 131/207 (63%), Gaps = 7/207 (3%) Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145 M ++ L++LG L L GW G+I + LP W+ +++ I+TA ++GLWMSC QSTG Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGP-AKARVAL 204 +QCK+YDS+LAL +Q+ARAL V AVLL FVA+ +++ G +CT P AK RVA+ Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 Query: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264 GG L++ GL L + W+A +V +EF++PS PV+ +YE G AL++GWA+ L ++GG Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 Query: 265 LLCCGAWVCTGRPDLSFPVKYSAPRRP 291 LCC P+ P P RP Sbjct: 181 FLCCTC------PEPERPNSSPQPYRP 201 >gi|40788011 claudin 8 [Homo sapiens] Length = 225 Score = 186 bits (471), Expect = 3e-47 Identities = 90/213 (42%), Positives = 134/213 (62%), Gaps = 5/213 (2%) Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145 M + ALEI GL L VG G + +P W+V+AF+++NIV + W+GLWM+CV Q+ Sbjct: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60 Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPG-PAKARVAL 204 MQCK+YDS+LALS ++QAAR L +A +++F+A + + G +CT C KA + L Sbjct: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120 Query: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264 T G++++ G++ L+P+ W AN ++R+FY+ V V+QK ELG ALY+GW +L+VGG Sbjct: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180 Query: 265 LLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDY 297 L CC + C + S +YS P T Y Sbjct: 181 LFCC-VFCCN---EKSSSYRYSIPSHRTTQKSY 209 >gi|6912316 claudin 17 [Homo sapiens] Length = 224 Score = 167 bits (423), Expect = 1e-41 Identities = 87/221 (39%), Positives = 131/221 (59%), Gaps = 10/221 (4%) Query: 91 LEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCK 150 L+I GLVL +G G + LP W+V+AF+ NI+ + W+GLWM+C+ Q+ +QCK Sbjct: 6 LQIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARVRLQCK 65 Query: 151 VYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGP-AKARVALTGGVL 209 Y S+LAL ++ ARAL AV L+ +AL + + G + C AKA + T GVL Sbjct: 66 FYSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLGTSGVL 125 Query: 210 YLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCLLCCG 269 ++ G+ L+P+ W ANI++R+FY+P++ + QK ELGAAL++GWA+ A+L +GG LLC Sbjct: 126 FILTGIFVLIPVSWTANIIIRDFYNPAIHIGQKRELGAALFLGWASAAVLFIGGGLLC-- 183 Query: 270 AWVCTGR-------PDLSFPVKYSAPRRPTATGDYDKKNYV 303 + C R P + V ++ RR T +YV Sbjct: 184 GFCCCNRKKQGYRYPVPGYRVPHTDKRRNTTMLSKTSTSYV 224 >gi|225703142 claudin 14 [Homo sapiens] Length = 239 Score = 166 bits (420), Expect = 2e-41 Identities = 87/209 (41%), Positives = 126/209 (60%), Gaps = 6/209 (2%) Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145 M S A+++LG +L +G G ++ LP W+ TA + NI+TA + KGLWM CV STG Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60 Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205 QC++Y S+LAL ++QAARAL V + LL+ +A + G +CT C PAK A+ Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120 Query: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265 GG L++ GLL +V + W N VV+ FY+P +P K+E+G ALY+G+ +++L ++GG L Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180 Query: 266 LCCGAWVCTGRPDLSFPVKYSAPRRPTAT 294 LC D + Y AP R T T Sbjct: 181 LCLSC------QDEAPYRPYQAPPRATTT 203 >gi|21536294 claudin 14 [Homo sapiens] Length = 239 Score = 166 bits (420), Expect = 2e-41 Identities = 87/209 (41%), Positives = 126/209 (60%), Gaps = 6/209 (2%) Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145 M S A+++LG +L +G G ++ LP W+ TA + NI+TA + KGLWM CV STG Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60 Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205 QC++Y S+LAL ++QAARAL V + LL+ +A + G +CT C PAK A+ Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120 Query: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265 GG L++ GLL +V + W N VV+ FY+P +P K+E+G ALY+G+ +++L ++GG L Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180 Query: 266 LCCGAWVCTGRPDLSFPVKYSAPRRPTAT 294 LC D + Y AP R T T Sbjct: 181 LCLSC------QDEAPYRPYQAPPRATTT 203 >gi|225703138 claudin 14 [Homo sapiens] Length = 239 Score = 166 bits (420), Expect = 2e-41 Identities = 87/209 (41%), Positives = 126/209 (60%), Gaps = 6/209 (2%) Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145 M S A+++LG +L +G G ++ LP W+ TA + NI+TA + KGLWM CV STG Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60 Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205 QC++Y S+LAL ++QAARAL V + LL+ +A + G +CT C PAK A+ Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120 Query: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265 GG L++ GLL +V + W N VV+ FY+P +P K+E+G ALY+G+ +++L ++GG L Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180 Query: 266 LCCGAWVCTGRPDLSFPVKYSAPRRPTAT 294 LC D + Y AP R T T Sbjct: 181 LCLSC------QDEAPYRPYQAPPRATTT 203 >gi|6912314 claudin 14 [Homo sapiens] Length = 239 Score = 166 bits (420), Expect = 2e-41 Identities = 87/209 (41%), Positives = 126/209 (60%), Gaps = 6/209 (2%) Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145 M S A+++LG +L +G G ++ LP W+ TA + NI+TA + KGLWM CV STG Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60 Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205 QC++Y S+LAL ++QAARAL V + LL+ +A + G +CT C PAK A+ Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120 Query: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265 GG L++ GLL +V + W N VV+ FY+P +P K+E+G ALY+G+ +++L ++GG L Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180 Query: 266 LCCGAWVCTGRPDLSFPVKYSAPRRPTAT 294 LC D + Y AP R T T Sbjct: 181 LCLSC------QDEAPYRPYQAPPRATTT 203 >gi|225703140 claudin 14 [Homo sapiens] Length = 239 Score = 166 bits (420), Expect = 2e-41 Identities = 87/209 (41%), Positives = 126/209 (60%), Gaps = 6/209 (2%) Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145 M S A+++LG +L +G G ++ LP W+ TA + NI+TA + KGLWM CV STG Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60 Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205 QC++Y S+LAL ++QAARAL V + LL+ +A + G +CT C PAK A+ Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120 Query: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265 GG L++ GLL +V + W N VV+ FY+P +P K+E+G ALY+G+ +++L ++GG L Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180 Query: 266 LCCGAWVCTGRPDLSFPVKYSAPRRPTAT 294 LC D + Y AP R T T Sbjct: 181 LCLSC------QDEAPYRPYQAPPRATTT 203 >gi|9966781 claudin 2 [Homo sapiens] Length = 230 Score = 149 bits (377), Expect = 2e-36 Identities = 69/182 (37%), Positives = 115/182 (63%) Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145 M S L+++G +L L+G G ++A LP W+ ++++ +IVTA KGLWM C STG Sbjct: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60 Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205 QC +Y ++L L ++QAA+A+ V++ ++ +A +++ G +CT AK RVA+ Sbjct: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA 120 Query: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265 GGV ++ GLL +P+ W + ++R+FY P VP S K+E+G ALY+G ++ ++ G + Sbjct: 121 GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII 180 Query: 266 LC 267 LC Sbjct: 181 LC 182 >gi|5921465 claudin 10 isoform b [Homo sapiens] Length = 228 Score = 137 bits (345), Expect = 1e-32 Identities = 71/184 (38%), Positives = 108/184 (58%), Gaps = 6/184 (3%) Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPM--WQVTAFLDHNIVTAQTTWKGLWMSCVVQS 143 M S A EI+ ++ + GW ++++ LP W+V+ +D ++T T W LW +CV S Sbjct: 1 MASTASEIIAFMVSISGW--VLVSSTLPTDYWKVST-IDGTVITTATYWANLWKACVTDS 57 Query: 144 TGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVA 203 TG CK + S+LAL +QA R L ++AV L F L G +CT AKA++A Sbjct: 58 TGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIA 117 Query: 204 LTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGG 263 G++++ GL ++ +AN + EF+DP + V QKYELGAAL+IGWA +L ++GG Sbjct: 118 CLAGIVFILSGLCSMTGCSLYANKITTEFFDP-LFVEQKYELGAALFIGWAGASLCIIGG 176 Query: 264 CLLC 267 + C Sbjct: 177 VIFC 180 >gi|47716519 claudin 20 [Homo sapiens] Length = 219 Score = 133 bits (335), Expect = 2e-31 Identities = 66/182 (36%), Positives = 100/182 (54%) Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145 M SA L++L +L L G G++ A LP W+V +D NI+TA GLWM C STG Sbjct: 1 MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60 Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205 C + S+L+L VQAARA V A +L+ + + + G +CT K+ + Sbjct: 61 MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA 120 Query: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265 GGV ++ G+ +L+ W+ ++ F D +VP S K+E G A+YIG+ + LL + G + Sbjct: 121 GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI 180 Query: 266 LC 267 C Sbjct: 181 FC 182 >gi|7656981 claudin 15 [Homo sapiens] Length = 228 Score = 133 bits (335), Expect = 2e-31 Identities = 82/219 (37%), Positives = 120/219 (54%), Gaps = 14/219 (6%) Query: 88 SAALEILGLVLCLVGWGGLILACGLP--MWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145 S A+E G + VG L+L LP W+V+ + N++T T ++ LW SC S G Sbjct: 2 SMAVETFGFFMATVGL--LMLGVTLPNSYWRVST-VHGNVITTNTIFENLWFSCATDSLG 58 Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVA-PGPAKARVAL 204 C + S+LALS +QA RAL ++A+LL F+ L + +AG +CT KA++A Sbjct: 59 VYNCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAA 118 Query: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264 T G L++ G+ +V + W+A + R+F+DP P KYELG ALY+GW+A+ + ++GG Sbjct: 119 TAGALHILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGL 177 Query: 265 LLCCGAWVCTGR---PDLSFPVKYSAP--RRPTATGDYD 298 LC C G P S Y AP P AT D + Sbjct: 178 CLCSAC--CCGSDEDPAASARRPYQAPVSVMPVATSDQE 214 >gi|33598916 claudin 10 isoform a [Homo sapiens] Length = 226 Score = 122 bits (307), Expect = 3e-28 Identities = 62/176 (35%), Positives = 101/176 (57%), Gaps = 2/176 (1%) Query: 92 EILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKV 151 +I LV + G+G L+ A W+VT +++TA ++GLWM+C + G C+ Sbjct: 5 QIWALVSGVGGFGALVAATTSNEWKVTTRAS-SVITATWVYQGLWMNCAGNALGSFHCRP 63 Query: 152 YDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALTGGVLYL 211 + ++ ++ +QA R L ++AV L F L G +CT AKA++A G++++ Sbjct: 64 HFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFI 123 Query: 212 FCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCLLC 267 GL ++ +AN + EF+DP + V QKYELGAAL+IGWA +L ++GG + C Sbjct: 124 LSGLCSMTGCSLYANKITTEFFDP-LFVEQKYELGAALFIGWAGASLCIIGGVIFC 178 >gi|169166402 PREDICTED: claudin-24-like [Homo sapiens] Length = 220 Score = 119 bits (297), Expect = 4e-27 Identities = 72/183 (39%), Positives = 105/183 (57%), Gaps = 5/183 (2%) Query: 90 ALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQC 149 A++ +GL+L L+GW I+ LP W+ LD N + T GLW +CV+Q MQC Sbjct: 8 AMQSVGLLLSLLGWILSIITTYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64 Query: 150 KVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTC-VAPGPAKARVALTGGV 208 K +DS LAL E++ +R L + L F+ L V+ G C + K R+ + GG+ Sbjct: 65 KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124 Query: 209 LYLFCGLLALVPLCWFANIVVREFYDPSVP-VSQKYELGAALYIGWAATALLMVGGCLLC 267 L G+ ALVP+ W A+ V+EF+D +VP ++E G AL++GW A L++GGCLL Sbjct: 125 LSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLN 184 Query: 268 CGA 270 C A Sbjct: 185 CAA 187 >gi|7705961 claudin 18 isoform 1 [Homo sapiens] Length = 261 Score = 118 bits (295), Expect = 7e-27 Identities = 62/194 (31%), Positives = 105/194 (54%), Gaps = 13/194 (6%) Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145 M + +++ +L ++G G I A G+ MW D N VT+ ++GLW SCV QS+G Sbjct: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYD-NPVTSVFQYEGLWRSCVRQSSG 59 Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVA-PGPAKARVAL 204 +C+ Y ++L L +QA RAL + ++L + L V++ +C + AKA + L Sbjct: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119 Query: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSV-----------PVSQKYELGAALYIGW 253 T G++++ GL A+ + FAN++V F+ + V +Y GAAL++GW Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179 Query: 254 AATALLMVGGCLLC 267 A L ++GG ++C Sbjct: 180 VAGGLTLIGGVMMC 193 >gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] Length = 220 Score = 117 bits (293), Expect = 1e-26 Identities = 71/183 (38%), Positives = 104/183 (56%), Gaps = 5/183 (2%) Query: 90 ALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQC 149 A++ +GL+L +GW I+ LP W+ LD N + T GLW +CV+Q MQC Sbjct: 8 AMQSVGLLLSFLGWILSIITTYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64 Query: 150 KVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTC-VAPGPAKARVALTGGV 208 K +DS LAL E++ +R L + L F+ L V+ G C + K R+ + GG+ Sbjct: 65 KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124 Query: 209 LYLFCGLLALVPLCWFANIVVREFYDPSVP-VSQKYELGAALYIGWAATALLMVGGCLLC 267 L G+ ALVP+ W A+ V+EF+D +VP ++E G AL++GW A L++GGCLL Sbjct: 125 LSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLN 184 Query: 268 CGA 270 C A Sbjct: 185 CAA 187 >gi|169166931 PREDICTED: claudin-24-like [Homo sapiens] Length = 220 Score = 117 bits (293), Expect = 1e-26 Identities = 71/183 (38%), Positives = 104/183 (56%), Gaps = 5/183 (2%) Query: 90 ALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQC 149 A++ +GL+L +GW I+ LP W+ LD N + T GLW +CV+Q MQC Sbjct: 8 AMQSVGLLLSFLGWILSIITTYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64 Query: 150 KVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTC-VAPGPAKARVALTGGV 208 K +DS LAL E++ +R L + L F+ L V+ G C + K R+ + GG+ Sbjct: 65 KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124 Query: 209 LYLFCGLLALVPLCWFANIVVREFYDPSVP-VSQKYELGAALYIGWAATALLMVGGCLLC 267 L G+ ALVP+ W A+ V+EF+D +VP ++E G AL++GW A L++GGCLL Sbjct: 125 LSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLN 184 Query: 268 CGA 270 C A Sbjct: 185 CAA 187 >gi|50345279 claudin 18 isoform 2 [Homo sapiens] Length = 261 Score = 115 bits (289), Expect = 4e-26 Identities = 65/194 (33%), Positives = 106/194 (54%), Gaps = 13/194 (6%) Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145 M A + LG V+ L+G G+I A + W T L +N VTA ++GLW SCV +S+G Sbjct: 1 MAVTACQGLGFVVSLIGIAGIIAATCMDQWS-TQDLYNNPVTAVFNYQGLWRSCVRESSG 59 Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVA-PGPAKARVAL 204 +C+ Y ++L L +QA RAL + ++L + L V++ +C + AKA + L Sbjct: 60 FTECRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119 Query: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSV-----------PVSQKYELGAALYIGW 253 T G++++ GL A+ + FAN++V F+ + V +Y GAAL++GW Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179 Query: 254 AATALLMVGGCLLC 267 A L ++GG ++C Sbjct: 180 VAGGLTLIGGVMMC 193 >gi|162417973 claudin 22 [Homo sapiens] Length = 220 Score = 113 bits (282), Expect = 2e-25 Identities = 70/181 (38%), Positives = 101/181 (55%), Gaps = 5/181 (2%) Query: 92 EILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKV 151 ++ G+ L L+GW L LP W+ LD N + T GLW +CV+Q MQCK Sbjct: 10 QLAGVSLSLLGWVLSCLTNYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQCKD 66 Query: 152 YDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTC-VAPGPAKARVALTGGVLY 210 +DS LAL E++ +R L + L F+ L V+ G C + K R+ + GG+L Sbjct: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126 Query: 211 LFCGLLALVPLCWFANIVVREFYDPSVP-VSQKYELGAALYIGWAATALLMVGGCLLCCG 269 G+ ALVP+ W A+ V+EF+D +VP ++E G AL++GW A L++GGCLL C Sbjct: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186 Query: 270 A 270 A Sbjct: 187 A 187 >gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] Length = 207 Score = 105 bits (263), Expect = 4e-23 Identities = 61/176 (34%), Positives = 94/176 (53%), Gaps = 21/176 (11%) Query: 92 EILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKV 151 +I LV + G+G L+ A W+VT +++TA ++GLWM+C G+ Sbjct: 5 QIWALVSGVGGFGALVAATTSNEWKVTTRAS-SVITATWVYQGLWMNCA----GY----- 54 Query: 152 YDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALTGGVLYL 211 +QA R L ++AV L F L G +CT AKA++A G++++ Sbjct: 55 ----------IQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFI 104 Query: 212 FCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCLLC 267 GL ++ +AN + EF+DP + V QKYELGAAL+IGWA +L ++GG + C Sbjct: 105 LSGLCSMTGCSLYANKITTEFFDP-LFVEQKYELGAALFIGWAGASLCIIGGVIFC 159 >gi|157820127 claudin-like [Homo sapiens] Length = 229 Score = 103 bits (258), Expect = 1e-22 Identities = 64/197 (32%), Positives = 103/197 (52%), Gaps = 7/197 (3%) Query: 89 AALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQ 148 A +++ GL+L L+GW + LP W+ L+ + +T G+W CV + Sbjct: 7 AKVQLGGLLLSLLGWVCSCVTTILPQWKT---LNLELNEMETWIMGIWEVCVDREEVATV 63 Query: 149 CKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTC-VAPGPAKARVALTGG 207 CK ++S L+L E+Q AR L V++ L + L + G++C K R+ L G Sbjct: 64 CKAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGR 123 Query: 208 VLYLFCGLLALVPLCWFANIVVREFYDPSVP-VSQKYELGAALYIGWAATALLMVGGCLL 266 L L+P+ W A+ +++F+D S+P + ++E G ALY+GWAA L +GG LL Sbjct: 124 TLEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLL 183 Query: 267 CCGAWVCTGRPDLSFPV 283 A C G+ D+ FP+ Sbjct: 184 IFSA--CLGKEDVPFPL 198 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.323 0.137 0.445 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,172,423 Number of Sequences: 37866 Number of extensions: 632321 Number of successful extensions: 3697 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 50 Number of HSP's successfully gapped in prelim test: 130 Number of HSP's that attempted gapping in prelim test: 3452 Number of HSP's gapped (non-prelim): 316 length of query: 303 length of database: 18,247,518 effective HSP length: 102 effective length of query: 201 effective length of database: 14,385,186 effective search space: 2891422386 effective search space used: 2891422386 T: 11 A: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.