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Search of human proteins with 195947372
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|195947372 claudin 5 [Homo sapiens]
(303 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|195947374 claudin 5 [Homo sapiens] 623 e-179
gi|195947372 claudin 5 [Homo sapiens] 623 e-179
gi|11141861 claudin 9 [Homo sapiens] 243 2e-64
gi|153792768 claudin 6 [Homo sapiens] 240 1e-63
gi|4502875 claudin 3 [Homo sapiens] 238 5e-63
gi|4502877 claudin 4 [Homo sapiens] 227 1e-59
gi|10863887 claudin 1 [Homo sapiens] 198 4e-51
gi|153792186 claudin 7 [Homo sapiens] 194 6e-50
gi|183979973 claudin 19 isoform a [Homo sapiens] 187 1e-47
gi|183979975 claudin 19 isoform b [Homo sapiens] 187 1e-47
gi|40788011 claudin 8 [Homo sapiens] 186 3e-47
gi|6912316 claudin 17 [Homo sapiens] 167 1e-41
gi|225703142 claudin 14 [Homo sapiens] 166 2e-41
gi|21536294 claudin 14 [Homo sapiens] 166 2e-41
gi|225703138 claudin 14 [Homo sapiens] 166 2e-41
gi|6912314 claudin 14 [Homo sapiens] 166 2e-41
gi|225703140 claudin 14 [Homo sapiens] 166 2e-41
gi|9966781 claudin 2 [Homo sapiens] 149 2e-36
gi|5921465 claudin 10 isoform b [Homo sapiens] 137 1e-32
gi|47716519 claudin 20 [Homo sapiens] 133 2e-31
gi|7656981 claudin 15 [Homo sapiens] 133 2e-31
gi|33598916 claudin 10 isoform a [Homo sapiens] 122 3e-28
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens] 119 4e-27
gi|7705961 claudin 18 isoform 1 [Homo sapiens] 118 7e-27
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] 117 1e-26
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens] 117 1e-26
gi|50345279 claudin 18 isoform 2 [Homo sapiens] 115 4e-26
gi|162417973 claudin 22 [Homo sapiens] 113 2e-25
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] 105 4e-23
gi|157820127 claudin-like [Homo sapiens] 103 1e-22
>gi|195947374 claudin 5 [Homo sapiens]
Length = 303
Score = 623 bits (1606), Expect = e-179
Identities = 303/303 (100%), Positives = 303/303 (100%)
Query: 1 MTRARIGCFGPGGRARGTESAPEPSKRVPPGRSWQTQEVRQTRGANGLGPRAGSAGAKAP 60
MTRARIGCFGPGGRARGTESAPEPSKRVPPGRSWQTQEVRQTRGANGLGPRAGSAGAKAP
Sbjct: 1 MTRARIGCFGPGGRARGTESAPEPSKRVPPGRSWQTQEVRQTRGANGLGPRAGSAGAKAP 60
Query: 61 GPAQGAAQHGLGGSAGLRVRVSPLAMGSAALEILGLVLCLVGWGGLILACGLPMWQVTAF 120
GPAQGAAQHGLGGSAGLRVRVSPLAMGSAALEILGLVLCLVGWGGLILACGLPMWQVTAF
Sbjct: 61 GPAQGAAQHGLGGSAGLRVRVSPLAMGSAALEILGLVLCLVGWGGLILACGLPMWQVTAF 120
Query: 121 LDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVAL 180
LDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVAL
Sbjct: 121 LDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVAL 180
Query: 181 FVTLAGAQCTTCVAPGPAKARVALTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVS 240
FVTLAGAQCTTCVAPGPAKARVALTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVS
Sbjct: 181 FVTLAGAQCTTCVAPGPAKARVALTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVS 240
Query: 241 QKYELGAALYIGWAATALLMVGGCLLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKK 300
QKYELGAALYIGWAATALLMVGGCLLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKK
Sbjct: 241 QKYELGAALYIGWAATALLMVGGCLLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKK 300
Query: 301 NYV 303
NYV
Sbjct: 301 NYV 303
>gi|195947372 claudin 5 [Homo sapiens]
Length = 303
Score = 623 bits (1606), Expect = e-179
Identities = 303/303 (100%), Positives = 303/303 (100%)
Query: 1 MTRARIGCFGPGGRARGTESAPEPSKRVPPGRSWQTQEVRQTRGANGLGPRAGSAGAKAP 60
MTRARIGCFGPGGRARGTESAPEPSKRVPPGRSWQTQEVRQTRGANGLGPRAGSAGAKAP
Sbjct: 1 MTRARIGCFGPGGRARGTESAPEPSKRVPPGRSWQTQEVRQTRGANGLGPRAGSAGAKAP 60
Query: 61 GPAQGAAQHGLGGSAGLRVRVSPLAMGSAALEILGLVLCLVGWGGLILACGLPMWQVTAF 120
GPAQGAAQHGLGGSAGLRVRVSPLAMGSAALEILGLVLCLVGWGGLILACGLPMWQVTAF
Sbjct: 61 GPAQGAAQHGLGGSAGLRVRVSPLAMGSAALEILGLVLCLVGWGGLILACGLPMWQVTAF 120
Query: 121 LDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVAL 180
LDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVAL
Sbjct: 121 LDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVAL 180
Query: 181 FVTLAGAQCTTCVAPGPAKARVALTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVS 240
FVTLAGAQCTTCVAPGPAKARVALTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVS
Sbjct: 181 FVTLAGAQCTTCVAPGPAKARVALTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVS 240
Query: 241 QKYELGAALYIGWAATALLMVGGCLLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKK 300
QKYELGAALYIGWAATALLMVGGCLLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKK
Sbjct: 241 QKYELGAALYIGWAATALLMVGGCLLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKK 300
Query: 301 NYV 303
NYV
Sbjct: 301 NYV 303
>gi|11141861 claudin 9 [Homo sapiens]
Length = 217
Score = 243 bits (620), Expect = 2e-64
Identities = 121/222 (54%), Positives = 160/222 (72%), Gaps = 9/222 (4%)
Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
M S LE+LG+ L ++GW G +++C LP+W+VTAF+ ++IV AQ W+GLWMSCVVQSTG
Sbjct: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205
MQCKVYDS+LAL ++QAARAL V A+LLA + L V + GAQCTTCV AKAR+ LT
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT 120
Query: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265
GV+ L G+L L+P+CW A+ ++++FY+P V + K ELGA+LY+GWAA ALLM+GG L
Sbjct: 121 AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL 180
Query: 266 LCCGAWVCTGRPDLSFP----VKYSAPRRPTATGDYDKKNYV 303
LCC C P + P + YS P R A+G DK++YV
Sbjct: 181 LCC---TCP-PPQVERPRGPRLGYSIPSRSGASG-LDKRDYV 217
>gi|153792768 claudin 6 [Homo sapiens]
Length = 220
Score = 240 bits (613), Expect = 1e-63
Identities = 116/220 (52%), Positives = 158/220 (71%), Gaps = 2/220 (0%)
Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
M SA ++ILG+VL L+GW +++C LPMW+VTAF+ ++IV AQ W+GLWMSCVVQSTG
Sbjct: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205
MQCKVYDS+LAL ++QAARAL V A+L+A L V LAGA+CTTCV +KAR+ LT
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT 120
Query: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265
G++++ G+L L+P+CW A+ ++R+FY+P V +QK ELGA+LY+GWAA+ LL++GG L
Sbjct: 121 SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL 180
Query: 266 LCCGAWVCTGRPDLSFPVKY--SAPRRPTATGDYDKKNYV 303
LCC + + +Y SAP +Y KNYV
Sbjct: 181 LCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKNYV 220
>gi|4502875 claudin 3 [Homo sapiens]
Length = 220
Score = 238 bits (607), Expect = 5e-63
Identities = 121/222 (54%), Positives = 153/222 (68%), Gaps = 9/222 (4%)
Query: 88 SAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHM 147
S LEI G L ++GW G I+ C LPMW+V+AF+ NI+T+Q W+GLWM+CVVQSTG M
Sbjct: 2 SMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQM 61
Query: 148 QCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALTGG 207
QCKVYDS+LAL ++QAARAL V A+LLA L V L GAQCT CV AKA++ + G
Sbjct: 62 QCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAG 121
Query: 208 VLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCLLC 267
VL+L LL LVP+ W AN ++R+FY+P VP +QK E+GA LY+GWAA AL ++GG LLC
Sbjct: 122 VLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC 181
Query: 268 CGAWVCTGRPD--LSFPVKYSAPRR--PTAT--GDYDKKNYV 303
C C R + V YSAPR P A+ YD+K+YV
Sbjct: 182 CS---CPPREKKYTATKVVYSAPRSTGPGASLGTGYDRKDYV 220
>gi|4502877 claudin 4 [Homo sapiens]
Length = 209
Score = 227 bits (578), Expect = 1e-59
Identities = 101/209 (48%), Positives = 150/209 (71%), Gaps = 3/209 (1%)
Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
M S L+++G+ L ++GW ++L C LPMW+VTAF+ NIVT+QT W+GLWM+CVVQSTG
Sbjct: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205
MQCKVYDS+LAL ++QAARAL + ++++A + + +++ G +CT C+ AKA+ +
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120
Query: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265
GV++L GL+ +VP+ W A+ ++++FY+P V QK E+GA+LY+GWAA+ LL++GG L
Sbjct: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180
Query: 266 LCCGAWVCTGRPDLSFPVKYSAPRRPTAT 294
LCC C R D + KYSA R A+
Sbjct: 181 LCCN---CPPRTDKPYSAKYSAARSAAAS 206
>gi|10863887 claudin 1 [Homo sapiens]
Length = 211
Score = 198 bits (504), Expect = 4e-51
Identities = 97/219 (44%), Positives = 138/219 (63%), Gaps = 9/219 (4%)
Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
M +A L++LG +L +GW G I++ LP W++ ++ NIVTAQ ++GLWMSCV QSTG
Sbjct: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPA-KARVAL 204
+QCKV+DS+L LS+ +QA RAL V +LL +A+FV G +C C+ K R+A+
Sbjct: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
Query: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264
GG ++L GL LV W+ N +V+EFYDP PV+ +YE G AL+ GWAA +L ++GG
Sbjct: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
Query: 265 LLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKKNYV 303
LLCC R S+P P+ ++G K+YV
Sbjct: 181 LLCCSC----PRKTTSYPTPRPYPKPAPSSG----KDYV 211
>gi|153792186 claudin 7 [Homo sapiens]
Length = 211
Score = 194 bits (494), Expect = 6e-50
Identities = 87/184 (47%), Positives = 128/184 (69%), Gaps = 1/184 (0%)
Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
M ++ L++LG + L+GW GL+ +P WQ++++ NI+TAQ +KGLWM CV QSTG
Sbjct: 1 MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPA-KARVAL 204
M CK+YDSVLALS +QA RAL V +++L F+A+FV G +CT C KAR+A+
Sbjct: 61 MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
Query: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264
GG++++ GL ALV W+ + +V +FY+P +P + KYE G A++IGWA +AL+++GG
Sbjct: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
Query: 265 LLCC 268
LL C
Sbjct: 181 LLSC 184
>gi|183979973 claudin 19 isoform a [Homo sapiens]
Length = 224
Score = 187 bits (475), Expect = 1e-47
Identities = 91/207 (43%), Positives = 131/207 (63%), Gaps = 7/207 (3%)
Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
M ++ L++LG L L GW G+I + LP W+ +++ I+TA ++GLWMSC QSTG
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGP-AKARVAL 204
+QCK+YDS+LAL +Q+ARAL V AVLL FVA+ +++ G +CT P AK RVA+
Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Query: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264
GG L++ GL L + W+A +V +EF++PS PV+ +YE G AL++GWA+ L ++GG
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
Query: 265 LLCCGAWVCTGRPDLSFPVKYSAPRRP 291
LCC P+ P P RP
Sbjct: 181 FLCCTC------PEPERPNSSPQPYRP 201
>gi|183979975 claudin 19 isoform b [Homo sapiens]
Length = 211
Score = 187 bits (475), Expect = 1e-47
Identities = 91/207 (43%), Positives = 131/207 (63%), Gaps = 7/207 (3%)
Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
M ++ L++LG L L GW G+I + LP W+ +++ I+TA ++GLWMSC QSTG
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGP-AKARVAL 204
+QCK+YDS+LAL +Q+ARAL V AVLL FVA+ +++ G +CT P AK RVA+
Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Query: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264
GG L++ GL L + W+A +V +EF++PS PV+ +YE G AL++GWA+ L ++GG
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
Query: 265 LLCCGAWVCTGRPDLSFPVKYSAPRRP 291
LCC P+ P P RP
Sbjct: 181 FLCCTC------PEPERPNSSPQPYRP 201
>gi|40788011 claudin 8 [Homo sapiens]
Length = 225
Score = 186 bits (471), Expect = 3e-47
Identities = 90/213 (42%), Positives = 134/213 (62%), Gaps = 5/213 (2%)
Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
M + ALEI GL L VG G + +P W+V+AF+++NIV + W+GLWM+CV Q+
Sbjct: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPG-PAKARVAL 204
MQCK+YDS+LALS ++QAAR L +A +++F+A + + G +CT C KA + L
Sbjct: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
Query: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264
T G++++ G++ L+P+ W AN ++R+FY+ V V+QK ELG ALY+GW +L+VGG
Sbjct: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
Query: 265 LLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDY 297
L CC + C + S +YS P T Y
Sbjct: 181 LFCC-VFCCN---EKSSSYRYSIPSHRTTQKSY 209
>gi|6912316 claudin 17 [Homo sapiens]
Length = 224
Score = 167 bits (423), Expect = 1e-41
Identities = 87/221 (39%), Positives = 131/221 (59%), Gaps = 10/221 (4%)
Query: 91 LEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCK 150
L+I GLVL +G G + LP W+V+AF+ NI+ + W+GLWM+C+ Q+ +QCK
Sbjct: 6 LQIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARVRLQCK 65
Query: 151 VYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGP-AKARVALTGGVL 209
Y S+LAL ++ ARAL AV L+ +AL + + G + C AKA + T GVL
Sbjct: 66 FYSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLGTSGVL 125
Query: 210 YLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCLLCCG 269
++ G+ L+P+ W ANI++R+FY+P++ + QK ELGAAL++GWA+ A+L +GG LLC
Sbjct: 126 FILTGIFVLIPVSWTANIIIRDFYNPAIHIGQKRELGAALFLGWASAAVLFIGGGLLC-- 183
Query: 270 AWVCTGR-------PDLSFPVKYSAPRRPTATGDYDKKNYV 303
+ C R P + V ++ RR T +YV
Sbjct: 184 GFCCCNRKKQGYRYPVPGYRVPHTDKRRNTTMLSKTSTSYV 224
>gi|225703142 claudin 14 [Homo sapiens]
Length = 239
Score = 166 bits (420), Expect = 2e-41
Identities = 87/209 (41%), Positives = 126/209 (60%), Gaps = 6/209 (2%)
Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
M S A+++LG +L +G G ++ LP W+ TA + NI+TA + KGLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205
QC++Y S+LAL ++QAARAL V + LL+ +A + G +CT C PAK A+
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265
GG L++ GLL +V + W N VV+ FY+P +P K+E+G ALY+G+ +++L ++GG L
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 266 LCCGAWVCTGRPDLSFPVKYSAPRRPTAT 294
LC D + Y AP R T T
Sbjct: 181 LCLSC------QDEAPYRPYQAPPRATTT 203
>gi|21536294 claudin 14 [Homo sapiens]
Length = 239
Score = 166 bits (420), Expect = 2e-41
Identities = 87/209 (41%), Positives = 126/209 (60%), Gaps = 6/209 (2%)
Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
M S A+++LG +L +G G ++ LP W+ TA + NI+TA + KGLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205
QC++Y S+LAL ++QAARAL V + LL+ +A + G +CT C PAK A+
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265
GG L++ GLL +V + W N VV+ FY+P +P K+E+G ALY+G+ +++L ++GG L
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 266 LCCGAWVCTGRPDLSFPVKYSAPRRPTAT 294
LC D + Y AP R T T
Sbjct: 181 LCLSC------QDEAPYRPYQAPPRATTT 203
>gi|225703138 claudin 14 [Homo sapiens]
Length = 239
Score = 166 bits (420), Expect = 2e-41
Identities = 87/209 (41%), Positives = 126/209 (60%), Gaps = 6/209 (2%)
Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
M S A+++LG +L +G G ++ LP W+ TA + NI+TA + KGLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205
QC++Y S+LAL ++QAARAL V + LL+ +A + G +CT C PAK A+
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265
GG L++ GLL +V + W N VV+ FY+P +P K+E+G ALY+G+ +++L ++GG L
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 266 LCCGAWVCTGRPDLSFPVKYSAPRRPTAT 294
LC D + Y AP R T T
Sbjct: 181 LCLSC------QDEAPYRPYQAPPRATTT 203
>gi|6912314 claudin 14 [Homo sapiens]
Length = 239
Score = 166 bits (420), Expect = 2e-41
Identities = 87/209 (41%), Positives = 126/209 (60%), Gaps = 6/209 (2%)
Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
M S A+++LG +L +G G ++ LP W+ TA + NI+TA + KGLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205
QC++Y S+LAL ++QAARAL V + LL+ +A + G +CT C PAK A+
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265
GG L++ GLL +V + W N VV+ FY+P +P K+E+G ALY+G+ +++L ++GG L
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 266 LCCGAWVCTGRPDLSFPVKYSAPRRPTAT 294
LC D + Y AP R T T
Sbjct: 181 LCLSC------QDEAPYRPYQAPPRATTT 203
>gi|225703140 claudin 14 [Homo sapiens]
Length = 239
Score = 166 bits (420), Expect = 2e-41
Identities = 87/209 (41%), Positives = 126/209 (60%), Gaps = 6/209 (2%)
Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
M S A+++LG +L +G G ++ LP W+ TA + NI+TA + KGLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205
QC++Y S+LAL ++QAARAL V + LL+ +A + G +CT C PAK A+
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265
GG L++ GLL +V + W N VV+ FY+P +P K+E+G ALY+G+ +++L ++GG L
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 266 LCCGAWVCTGRPDLSFPVKYSAPRRPTAT 294
LC D + Y AP R T T
Sbjct: 181 LCLSC------QDEAPYRPYQAPPRATTT 203
>gi|9966781 claudin 2 [Homo sapiens]
Length = 230
Score = 149 bits (377), Expect = 2e-36
Identities = 69/182 (37%), Positives = 115/182 (63%)
Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
M S L+++G +L L+G G ++A LP W+ ++++ +IVTA KGLWM C STG
Sbjct: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205
QC +Y ++L L ++QAA+A+ V++ ++ +A +++ G +CT AK RVA+
Sbjct: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA 120
Query: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265
GGV ++ GLL +P+ W + ++R+FY P VP S K+E+G ALY+G ++ ++ G +
Sbjct: 121 GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII 180
Query: 266 LC 267
LC
Sbjct: 181 LC 182
>gi|5921465 claudin 10 isoform b [Homo sapiens]
Length = 228
Score = 137 bits (345), Expect = 1e-32
Identities = 71/184 (38%), Positives = 108/184 (58%), Gaps = 6/184 (3%)
Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPM--WQVTAFLDHNIVTAQTTWKGLWMSCVVQS 143
M S A EI+ ++ + GW ++++ LP W+V+ +D ++T T W LW +CV S
Sbjct: 1 MASTASEIIAFMVSISGW--VLVSSTLPTDYWKVST-IDGTVITTATYWANLWKACVTDS 57
Query: 144 TGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVA 203
TG CK + S+LAL +QA R L ++AV L F L G +CT AKA++A
Sbjct: 58 TGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIA 117
Query: 204 LTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGG 263
G++++ GL ++ +AN + EF+DP + V QKYELGAAL+IGWA +L ++GG
Sbjct: 118 CLAGIVFILSGLCSMTGCSLYANKITTEFFDP-LFVEQKYELGAALFIGWAGASLCIIGG 176
Query: 264 CLLC 267
+ C
Sbjct: 177 VIFC 180
>gi|47716519 claudin 20 [Homo sapiens]
Length = 219
Score = 133 bits (335), Expect = 2e-31
Identities = 66/182 (36%), Positives = 100/182 (54%)
Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
M SA L++L +L L G G++ A LP W+V +D NI+TA GLWM C STG
Sbjct: 1 MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205
C + S+L+L VQAARA V A +L+ + + + G +CT K+ +
Sbjct: 61 MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA 120
Query: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265
GGV ++ G+ +L+ W+ ++ F D +VP S K+E G A+YIG+ + LL + G +
Sbjct: 121 GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI 180
Query: 266 LC 267
C
Sbjct: 181 FC 182
>gi|7656981 claudin 15 [Homo sapiens]
Length = 228
Score = 133 bits (335), Expect = 2e-31
Identities = 82/219 (37%), Positives = 120/219 (54%), Gaps = 14/219 (6%)
Query: 88 SAALEILGLVLCLVGWGGLILACGLP--MWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
S A+E G + VG L+L LP W+V+ + N++T T ++ LW SC S G
Sbjct: 2 SMAVETFGFFMATVGL--LMLGVTLPNSYWRVST-VHGNVITTNTIFENLWFSCATDSLG 58
Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVA-PGPAKARVAL 204
C + S+LALS +QA RAL ++A+LL F+ L + +AG +CT KA++A
Sbjct: 59 VYNCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAA 118
Query: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264
T G L++ G+ +V + W+A + R+F+DP P KYELG ALY+GW+A+ + ++GG
Sbjct: 119 TAGALHILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGL 177
Query: 265 LLCCGAWVCTGR---PDLSFPVKYSAP--RRPTATGDYD 298
LC C G P S Y AP P AT D +
Sbjct: 178 CLCSAC--CCGSDEDPAASARRPYQAPVSVMPVATSDQE 214
>gi|33598916 claudin 10 isoform a [Homo sapiens]
Length = 226
Score = 122 bits (307), Expect = 3e-28
Identities = 62/176 (35%), Positives = 101/176 (57%), Gaps = 2/176 (1%)
Query: 92 EILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKV 151
+I LV + G+G L+ A W+VT +++TA ++GLWM+C + G C+
Sbjct: 5 QIWALVSGVGGFGALVAATTSNEWKVTTRAS-SVITATWVYQGLWMNCAGNALGSFHCRP 63
Query: 152 YDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALTGGVLYL 211
+ ++ ++ +QA R L ++AV L F L G +CT AKA++A G++++
Sbjct: 64 HFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFI 123
Query: 212 FCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCLLC 267
GL ++ +AN + EF+DP + V QKYELGAAL+IGWA +L ++GG + C
Sbjct: 124 LSGLCSMTGCSLYANKITTEFFDP-LFVEQKYELGAALFIGWAGASLCIIGGVIFC 178
>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 119 bits (297), Expect = 4e-27
Identities = 72/183 (39%), Positives = 105/183 (57%), Gaps = 5/183 (2%)
Query: 90 ALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQC 149
A++ +GL+L L+GW I+ LP W+ LD N + T GLW +CV+Q MQC
Sbjct: 8 AMQSVGLLLSLLGWILSIITTYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64
Query: 150 KVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTC-VAPGPAKARVALTGGV 208
K +DS LAL E++ +R L + L F+ L V+ G C + K R+ + GG+
Sbjct: 65 KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
Query: 209 LYLFCGLLALVPLCWFANIVVREFYDPSVP-VSQKYELGAALYIGWAATALLMVGGCLLC 267
L G+ ALVP+ W A+ V+EF+D +VP ++E G AL++GW A L++GGCLL
Sbjct: 125 LSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLN 184
Query: 268 CGA 270
C A
Sbjct: 185 CAA 187
>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
Length = 261
Score = 118 bits (295), Expect = 7e-27
Identities = 62/194 (31%), Positives = 105/194 (54%), Gaps = 13/194 (6%)
Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
M + +++ +L ++G G I A G+ MW D N VT+ ++GLW SCV QS+G
Sbjct: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYD-NPVTSVFQYEGLWRSCVRQSSG 59
Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVA-PGPAKARVAL 204
+C+ Y ++L L +QA RAL + ++L + L V++ +C + AKA + L
Sbjct: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
Query: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSV-----------PVSQKYELGAALYIGW 253
T G++++ GL A+ + FAN++V F+ + V +Y GAAL++GW
Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
Query: 254 AATALLMVGGCLLC 267
A L ++GG ++C
Sbjct: 180 VAGGLTLIGGVMMC 193
>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 117 bits (293), Expect = 1e-26
Identities = 71/183 (38%), Positives = 104/183 (56%), Gaps = 5/183 (2%)
Query: 90 ALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQC 149
A++ +GL+L +GW I+ LP W+ LD N + T GLW +CV+Q MQC
Sbjct: 8 AMQSVGLLLSFLGWILSIITTYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64
Query: 150 KVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTC-VAPGPAKARVALTGGV 208
K +DS LAL E++ +R L + L F+ L V+ G C + K R+ + GG+
Sbjct: 65 KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
Query: 209 LYLFCGLLALVPLCWFANIVVREFYDPSVP-VSQKYELGAALYIGWAATALLMVGGCLLC 267
L G+ ALVP+ W A+ V+EF+D +VP ++E G AL++GW A L++GGCLL
Sbjct: 125 LSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLN 184
Query: 268 CGA 270
C A
Sbjct: 185 CAA 187
>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 117 bits (293), Expect = 1e-26
Identities = 71/183 (38%), Positives = 104/183 (56%), Gaps = 5/183 (2%)
Query: 90 ALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQC 149
A++ +GL+L +GW I+ LP W+ LD N + T GLW +CV+Q MQC
Sbjct: 8 AMQSVGLLLSFLGWILSIITTYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64
Query: 150 KVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTC-VAPGPAKARVALTGGV 208
K +DS LAL E++ +R L + L F+ L V+ G C + K R+ + GG+
Sbjct: 65 KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
Query: 209 LYLFCGLLALVPLCWFANIVVREFYDPSVP-VSQKYELGAALYIGWAATALLMVGGCLLC 267
L G+ ALVP+ W A+ V+EF+D +VP ++E G AL++GW A L++GGCLL
Sbjct: 125 LSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLN 184
Query: 268 CGA 270
C A
Sbjct: 185 CAA 187
>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
Length = 261
Score = 115 bits (289), Expect = 4e-26
Identities = 65/194 (33%), Positives = 106/194 (54%), Gaps = 13/194 (6%)
Query: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
M A + LG V+ L+G G+I A + W T L +N VTA ++GLW SCV +S+G
Sbjct: 1 MAVTACQGLGFVVSLIGIAGIIAATCMDQWS-TQDLYNNPVTAVFNYQGLWRSCVRESSG 59
Query: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVA-PGPAKARVAL 204
+C+ Y ++L L +QA RAL + ++L + L V++ +C + AKA + L
Sbjct: 60 FTECRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
Query: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSV-----------PVSQKYELGAALYIGW 253
T G++++ GL A+ + FAN++V F+ + V +Y GAAL++GW
Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
Query: 254 AATALLMVGGCLLC 267
A L ++GG ++C
Sbjct: 180 VAGGLTLIGGVMMC 193
>gi|162417973 claudin 22 [Homo sapiens]
Length = 220
Score = 113 bits (282), Expect = 2e-25
Identities = 70/181 (38%), Positives = 101/181 (55%), Gaps = 5/181 (2%)
Query: 92 EILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKV 151
++ G+ L L+GW L LP W+ LD N + T GLW +CV+Q MQCK
Sbjct: 10 QLAGVSLSLLGWVLSCLTNYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQCKD 66
Query: 152 YDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTC-VAPGPAKARVALTGGVLY 210
+DS LAL E++ +R L + L F+ L V+ G C + K R+ + GG+L
Sbjct: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126
Query: 211 LFCGLLALVPLCWFANIVVREFYDPSVP-VSQKYELGAALYIGWAATALLMVGGCLLCCG 269
G+ ALVP+ W A+ V+EF+D +VP ++E G AL++GW A L++GGCLL C
Sbjct: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186
Query: 270 A 270
A
Sbjct: 187 A 187
>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
Length = 207
Score = 105 bits (263), Expect = 4e-23
Identities = 61/176 (34%), Positives = 94/176 (53%), Gaps = 21/176 (11%)
Query: 92 EILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKV 151
+I LV + G+G L+ A W+VT +++TA ++GLWM+C G+
Sbjct: 5 QIWALVSGVGGFGALVAATTSNEWKVTTRAS-SVITATWVYQGLWMNCA----GY----- 54
Query: 152 YDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALTGGVLYL 211
+QA R L ++AV L F L G +CT AKA++A G++++
Sbjct: 55 ----------IQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFI 104
Query: 212 FCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCLLC 267
GL ++ +AN + EF+DP + V QKYELGAAL+IGWA +L ++GG + C
Sbjct: 105 LSGLCSMTGCSLYANKITTEFFDP-LFVEQKYELGAALFIGWAGASLCIIGGVIFC 159
>gi|157820127 claudin-like [Homo sapiens]
Length = 229
Score = 103 bits (258), Expect = 1e-22
Identities = 64/197 (32%), Positives = 103/197 (52%), Gaps = 7/197 (3%)
Query: 89 AALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQ 148
A +++ GL+L L+GW + LP W+ L+ + +T G+W CV +
Sbjct: 7 AKVQLGGLLLSLLGWVCSCVTTILPQWKT---LNLELNEMETWIMGIWEVCVDREEVATV 63
Query: 149 CKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTC-VAPGPAKARVALTGG 207
CK ++S L+L E+Q AR L V++ L + L + G++C K R+ L G
Sbjct: 64 CKAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGR 123
Query: 208 VLYLFCGLLALVPLCWFANIVVREFYDPSVP-VSQKYELGAALYIGWAATALLMVGGCLL 266
L L+P+ W A+ +++F+D S+P + ++E G ALY+GWAA L +GG LL
Sbjct: 124 TLEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLL 183
Query: 267 CCGAWVCTGRPDLSFPV 283
A C G+ D+ FP+
Sbjct: 184 IFSA--CLGKEDVPFPL 198
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.137 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,172,423
Number of Sequences: 37866
Number of extensions: 632321
Number of successful extensions: 3697
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 130
Number of HSP's that attempted gapping in prelim test: 3452
Number of HSP's gapped (non-prelim): 316
length of query: 303
length of database: 18,247,518
effective HSP length: 102
effective length of query: 201
effective length of database: 14,385,186
effective search space: 2891422386
effective search space used: 2891422386
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.