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Search of human proteins with 194688149
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194688149 protein phosphatase 3, catalytic subunit, alpha
isoform isoform 3 [Homo sapiens]
(469 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194688149 protein phosphatase 3, catalytic subunit, alpha iso... 952 0.0
gi|194688147 protein phosphatase 3, catalytic subunit, alpha iso... 931 0.0
gi|6715568 protein phosphatase 3, catalytic subunit, alpha isofo... 923 0.0
gi|215272354 protein phosphatase 3, catalytic subunit, beta isof... 765 0.0
gi|215272352 protein phosphatase 3, catalytic subunit, beta isof... 757 0.0
gi|11036640 protein phosphatase 3, catalytic subunit, beta isofo... 756 0.0
gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Hom... 724 0.0
gi|4506007 protein phosphatase 1, catalytic subunit, gamma isofo... 225 8e-59
gi|56790945 protein phosphatase 1, catalytic subunit, alpha isof... 224 1e-58
gi|4506003 protein phosphatase 1, catalytic subunit, alpha isofo... 224 1e-58
gi|46249376 protein phosphatase 1, catalytic subunit, beta isofo... 220 2e-57
gi|4506005 protein phosphatase 1, catalytic subunit, beta isofor... 220 2e-57
gi|57222565 protein phosphatase 2, catalytic subunit, beta isofo... 220 2e-57
gi|4758952 protein phosphatase 2, catalytic subunit, beta isofor... 220 2e-57
gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens] 219 4e-57
gi|4506017 protein phosphatase 2, catalytic subunit, alpha isofo... 218 1e-56
gi|4506029 protein phosphatase 6, catalytic subunit isoform b [H... 212 5e-55
gi|183603929 protein phosphatase 6, catalytic subunit isoform a ... 211 1e-54
gi|45827798 protein phosphatase 1, catalytic subunit, alpha isof... 208 7e-54
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 203 2e-52
gi|183603931 protein phosphatase 6, catalytic subunit isoform c ... 176 4e-44
gi|23312374 protein phosphatase with EF hand calcium-binding dom... 122 5e-28
gi|23312380 protein phosphatase with EF hand calcium-binding dom... 111 1e-24
gi|239752750 PREDICTED: similar to protein phosphatase 2, cataly... 107 2e-23
gi|239747318 PREDICTED: similar to protein phosphatase 2, cataly... 107 2e-23
gi|239741140 PREDICTED: similar to protein phosphatase 2, cataly... 107 2e-23
gi|23312386 serine/threonine protein phosphatase with EF-hand mo... 101 2e-21
gi|23312378 protein phosphatase with EF hand calcium-binding dom... 95 1e-19
gi|156104878 glutaminase [Homo sapiens] 33 0.73
gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens] 30 6.1
>gi|194688149 protein phosphatase 3, catalytic subunit, alpha
isoform isoform 3 [Homo sapiens]
Length = 469
Score = 952 bits (2460), Expect = 0.0
Identities = 469/469 (100%), Positives = 469/469 (100%)
Query: 1 MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV 60
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
Sbjct: 1 MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV 60
Query: 61 ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV 120
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
Sbjct: 61 ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV 120
Query: 121 DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD 180
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
Sbjct: 121 DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD 180
Query: 181 AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG 240
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
Sbjct: 181 AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG 240
Query: 241 NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP 300
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
Sbjct: 241 NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP 300
Query: 301 SLITIFSAPNYLDVYNNKVTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRA 360
SLITIFSAPNYLDVYNNKVTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRA
Sbjct: 301 SLITIFSAPNYLDVYNNKVTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRA 360
Query: 361 IGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSAIKGFSPQHKITSFEE 420
IGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSAIKGFSPQHKITSFEE
Sbjct: 361 IGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSAIKGFSPQHKITSFEE 420
Query: 421 AKGLDRINERMPPRRDAMPSDANLNSINKALTSETNGTDSNGSNSSNIQ 469
AKGLDRINERMPPRRDAMPSDANLNSINKALTSETNGTDSNGSNSSNIQ
Sbjct: 421 AKGLDRINERMPPRRDAMPSDANLNSINKALTSETNGTDSNGSNSSNIQ 469
>gi|194688147 protein phosphatase 3, catalytic subunit, alpha
isoform isoform 2 [Homo sapiens]
Length = 511
Score = 931 bits (2407), Expect = 0.0
Identities = 469/511 (91%), Positives = 469/511 (91%), Gaps = 42/511 (8%)
Query: 1 MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV 60
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
Sbjct: 1 MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV 60
Query: 61 ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV 120
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
Sbjct: 61 ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV 120
Query: 121 DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD 180
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
Sbjct: 121 DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD 180
Query: 181 AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG 240
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
Sbjct: 181 AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG 240
Query: 241 NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP 300
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
Sbjct: 241 NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP 300
Query: 301 SLITIFSAPNYLDVYNN------------------------------------------K 318
SLITIFSAPNYLDVYNN K
Sbjct: 301 SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK 360
Query: 319 VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV 378
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
Sbjct: 361 VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV 420
Query: 379 LTLKGLTPTGMLPSGVLSGGKQTLQSAIKGFSPQHKITSFEEAKGLDRINERMPPRRDAM 438
LTLKGLTPTGMLPSGVLSGGKQTLQSAIKGFSPQHKITSFEEAKGLDRINERMPPRRDAM
Sbjct: 421 LTLKGLTPTGMLPSGVLSGGKQTLQSAIKGFSPQHKITSFEEAKGLDRINERMPPRRDAM 480
Query: 439 PSDANLNSINKALTSETNGTDSNGSNSSNIQ 469
PSDANLNSINKALTSETNGTDSNGSNSSNIQ
Sbjct: 481 PSDANLNSINKALTSETNGTDSNGSNSSNIQ 511
>gi|6715568 protein phosphatase 3, catalytic subunit, alpha isoform
isoform 1 [Homo sapiens]
Length = 521
Score = 923 bits (2386), Expect = 0.0
Identities = 469/521 (90%), Positives = 469/521 (90%), Gaps = 52/521 (9%)
Query: 1 MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV 60
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
Sbjct: 1 MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV 60
Query: 61 ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV 120
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
Sbjct: 61 ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV 120
Query: 121 DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD 180
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
Sbjct: 121 DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD 180
Query: 181 AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG 240
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
Sbjct: 181 AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG 240
Query: 241 NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP 300
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
Sbjct: 241 NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP 300
Query: 301 SLITIFSAPNYLDVYNN------------------------------------------K 318
SLITIFSAPNYLDVYNN K
Sbjct: 301 SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK 360
Query: 319 VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV 378
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
Sbjct: 361 VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV 420
Query: 379 LTLKGLTPTGMLPSGVLSGGKQTLQS----------AIKGFSPQHKITSFEEAKGLDRIN 428
LTLKGLTPTGMLPSGVLSGGKQTLQS AIKGFSPQHKITSFEEAKGLDRIN
Sbjct: 421 LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN 480
Query: 429 ERMPPRRDAMPSDANLNSINKALTSETNGTDSNGSNSSNIQ 469
ERMPPRRDAMPSDANLNSINKALTSETNGTDSNGSNSSNIQ
Sbjct: 481 ERMPPRRDAMPSDANLNSINKALTSETNGTDSNGSNSSNIQ 521
>gi|215272354 protein phosphatase 3, catalytic subunit, beta isoform
c [Homo sapiens]
Length = 515
Score = 765 bits (1976), Expect = 0.0
Identities = 380/501 (75%), Positives = 423/501 (84%), Gaps = 44/501 (8%)
Query: 4 PKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALR 63
P P DRVVKAVPFPP+HRLT++EVFD DG PRVD+LK HL+KEGR++E +ALR
Sbjct: 13 PPPPPPPPPGADRVVKAVPFPPTHRLTSEEVFDLDGIPRVDVLKNHLVKEGRVDEEIALR 72
Query: 64 IITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRG 123
II EGA+ILR+EK +++++AP+TVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRG
Sbjct: 73 IINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRG 132
Query: 124 YFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFD 183
YFSIECVLYLW LKILYP TLFLLRGNHECRHLTEYFTFKQECKIKYSERVY+ACM+AFD
Sbjct: 133 YFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFD 192
Query: 184 CLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEK 243
LPLAAL+NQQFLCVHGGLSPEI+TLDDIR+LDRFKEPPA+GPMCD+LWSDP EDFGNEK
Sbjct: 193 SLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEK 252
Query: 244 TQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLI 303
+QEHF+HNTVRGCSYFY+YPAVCEFLQ+NNLLSI+RAHEAQDAGYRMYRKSQTTGFPSLI
Sbjct: 253 SQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLI 312
Query: 304 TIFSAPNYLDVYNN------------------------------------------KVTE 321
TIFSAPNYLDVYNN KVTE
Sbjct: 313 TIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTE 372
Query: 322 MLVNVLNICSDDELGSE-EDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESVLT 380
MLVNVL+ICSDDEL +E ED FD +AAARKE+IRNKIRAIGKMARVFSVLREESESVLT
Sbjct: 373 MLVNVLSICSDDELMTEGEDQFDVGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLT 432
Query: 381 LKGLTPTGMLPSGVLSGGKQTLQSAIKGFSPQHKITSFEEAKGLDRINERMPPRRDAMPS 440
LKGLTPTGMLPSGVL+GG+QTLQSAI+GFSP H+I SFEEAKGLDRINERMPPR+DA+
Sbjct: 433 LKGLTPTGMLPSGVLAGGRQTLQSAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQ 492
Query: 441 DANLNSINKALTSETNGTDSN 461
D NS+N A +E +GT ++
Sbjct: 493 D-GFNSLNTAHATENHGTGNH 512
>gi|215272352 protein phosphatase 3, catalytic subunit, beta isoform
a [Homo sapiens]
Length = 525
Score = 757 bits (1955), Expect = 0.0
Identities = 380/511 (74%), Positives = 423/511 (82%), Gaps = 54/511 (10%)
Query: 4 PKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALR 63
P P DRVVKAVPFPP+HRLT++EVFD DG PRVD+LK HL+KEGR++E +ALR
Sbjct: 13 PPPPPPPPPGADRVVKAVPFPPTHRLTSEEVFDLDGIPRVDVLKNHLVKEGRVDEEIALR 72
Query: 64 IITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRG 123
II EGA+ILR+EK +++++AP+TVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRG
Sbjct: 73 IINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRG 132
Query: 124 YFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFD 183
YFSIECVLYLW LKILYP TLFLLRGNHECRHLTEYFTFKQECKIKYSERVY+ACM+AFD
Sbjct: 133 YFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFD 192
Query: 184 CLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEK 243
LPLAAL+NQQFLCVHGGLSPEI+TLDDIR+LDRFKEPPA+GPMCD+LWSDP EDFGNEK
Sbjct: 193 SLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEK 252
Query: 244 TQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLI 303
+QEHF+HNTVRGCSYFY+YPAVCEFLQ+NNLLSI+RAHEAQDAGYRMYRKSQTTGFPSLI
Sbjct: 253 SQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLI 312
Query: 304 TIFSAPNYLDVYNN------------------------------------------KVTE 321
TIFSAPNYLDVYNN KVTE
Sbjct: 313 TIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTE 372
Query: 322 MLVNVLNICSDDELGSE-EDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESVLT 380
MLVNVL+ICSDDEL +E ED FD +AAARKE+IRNKIRAIGKMARVFSVLREESESVLT
Sbjct: 373 MLVNVLSICSDDELMTEGEDQFDVGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLT 432
Query: 381 LKGLTPTGMLPSGVLSGGKQTLQS----------AIKGFSPQHKITSFEEAKGLDRINER 430
LKGLTPTGMLPSGVL+GG+QTLQS AI+GFSP H+I SFEEAKGLDRINER
Sbjct: 433 LKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINER 492
Query: 431 MPPRRDAMPSDANLNSINKALTSETNGTDSN 461
MPPR+DA+ D NS+N A +E +GT ++
Sbjct: 493 MPPRKDAVQQD-GFNSLNTAHATENHGTGNH 522
>gi|11036640 protein phosphatase 3, catalytic subunit, beta isoform
b [Homo sapiens]
Length = 524
Score = 756 bits (1952), Expect = 0.0
Identities = 381/511 (74%), Positives = 424/511 (82%), Gaps = 55/511 (10%)
Query: 4 PKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALR 63
P P DRVVKAVPFPP+HRLT++EVFD DG PRVD+LK HL+KEGR++E +ALR
Sbjct: 13 PPPPPPPPPGADRVVKAVPFPPTHRLTSEEVFDLDGIPRVDVLKNHLVKEGRVDEEIALR 72
Query: 64 IITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRG 123
II EGA+ILR+EK +++++AP+TVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRG
Sbjct: 73 IINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRG 132
Query: 124 YFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFD 183
YFSIECVLYLW LKILYP TLFLLRGNHECRHLTEYFTFKQECKIKYSERVY+ACM+AFD
Sbjct: 133 YFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFD 192
Query: 184 CLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEK 243
LPLAAL+NQQFLCVHGGLSPEI+TLDDIR+LDRFKEPPA+GPMCD+LWSDP EDFGNEK
Sbjct: 193 SLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEK 252
Query: 244 TQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLI 303
+QEHF+HNTVRGCSYFY+YPAVCEFLQ+NNLLSI+RAHEAQDAGYRMYRKSQTTGFPSLI
Sbjct: 253 SQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLI 312
Query: 304 TIFSAPNYLDVYNN------------------------------------------KVTE 321
TIFSAPNYLDVYNN KVTE
Sbjct: 313 TIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTE 372
Query: 322 MLVNVLNICSDDELGSE-EDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESVLT 380
MLVNVL+ICSDDEL +E ED FDG +AAARKE+IRNKIRAIGKMARVFSVLREESESVLT
Sbjct: 373 MLVNVLSICSDDELMTEGEDQFDG-SAAARKEIIRNKIRAIGKMARVFSVLREESESVLT 431
Query: 381 LKGLTPTGMLPSGVLSGGKQTLQS----------AIKGFSPQHKITSFEEAKGLDRINER 430
LKGLTPTGMLPSGVL+GG+QTLQS AI+GFSP H+I SFEEAKGLDRINER
Sbjct: 432 LKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINER 491
Query: 431 MPPRRDAMPSDANLNSINKALTSETNGTDSN 461
MPPR+DA+ D NS+N A +E +GT ++
Sbjct: 492 MPPRKDAVQQD-GFNSLNTAHATENHGTGNH 521
>gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Homo
sapiens]
Length = 512
Score = 724 bits (1870), Expect = 0.0
Identities = 360/501 (71%), Positives = 413/501 (82%), Gaps = 55/501 (10%)
Query: 11 LSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALRIITEGAS 70
LSTTDRV+KAVPFPP+ RLT KEVF+N GKP+VD+LK HL+KEGRLEE VAL+II +GA+
Sbjct: 8 LSTTDRVIKAVPFPPTQRLTFKEVFEN-GKPKVDVLKNHLVKEGRLEEEVALKIINDGAA 66
Query: 71 ILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 130
ILRQEK ++++DAP+TVCGDIHGQFFDLMKLFEVGGSP+NTRYLFLGDYVDRGYFSIECV
Sbjct: 67 ILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126
Query: 131 LYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAAL 190
LYLW+LKI +PKTLFLLRGNHECRHLT+YFTFKQEC+IKYSE+VYDACM+ FDCLPLAAL
Sbjct: 127 LYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAAL 186
Query: 191 MNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTH 250
+NQQFLCVHGG+SPEI +LDDIRKLDRF EPPA+GP+CD+LWSDP ED+GNEKT EH+TH
Sbjct: 187 LNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTH 246
Query: 251 NTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPN 310
NTVRGCSYFYSYPAVCEFLQ+NNLLSI+RAHEAQDAGYRMYRKSQ TGFPSLITIFSAPN
Sbjct: 247 NTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPN 306
Query: 311 YLDVYNN------------------------------------------KVTEMLVNVLN 328
YLDVYNN KVTEMLVNVLN
Sbjct: 307 YLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLN 366
Query: 329 ICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTG 388
ICSDDEL S+++ +G+T RKE+IRNKIRAIGKMARVFS+LR+ESESVLTLKGLTPTG
Sbjct: 367 ICSDDELISDDEA-EGST-TVRKEIIRNKIRAIGKMARVFSILRQESESVLTLKGLTPTG 424
Query: 389 MLPSGVLSGGKQTLQS----------AIKGFSPQHKITSFEEAKGLDRINERMPPRRDAM 438
LP GVLSGGKQT+++ AI+GFS QHKI SFEEA+GLDRINERMPPR+D++
Sbjct: 425 TLPLGVLSGGKQTIETATVEAVEAREAIRGFSLQHKIRSFEEARGLDRINERMPPRKDSI 484
Query: 439 PSDANLNSINKALTSETNGTD 459
+ + S+ A + + +D
Sbjct: 485 HAGGPMKSVTSAHSHAAHRSD 505
>gi|4506007 protein phosphatase 1, catalytic subunit, gamma isoform
[Homo sapiens]
Length = 323
Score = 225 bits (573), Expect = 8e-59
Identities = 115/295 (38%), Positives = 174/295 (58%), Gaps = 13/295 (4%)
Query: 52 KEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANT 111
K +L+E+ + + I + LL+++AP+ +CGDIHGQ++DL++LFE GG P +
Sbjct: 26 KNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 85
Query: 112 RYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYS 171
YLFLGDYVDRG S+E + L A KI YP+ FLLRGNHEC + + F ECK +Y+
Sbjct: 86 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 145
Query: 172 ERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDIL 231
+++ D F+CLP+AA+++++ C HGGLSP++ +++ IR++ R + P G +CD+L
Sbjct: 146 IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 205
Query: 232 WSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMY 291
WSDP +D + RG S+ + V +FL ++L I RAH+ + GY +
Sbjct: 206 WSDPDKDVLGWGEND-------RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFF 258
Query: 292 RKSQTTGFPSLITIFSAPNYLDVYNNKVTEMLVNVLNICSDDELGSEEDGFDGAT 346
K Q L+T+FSAPNY ++N M V+ +CS L E AT
Sbjct: 259 AKRQ------LVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKPNAT 307
>gi|56790945 protein phosphatase 1, catalytic subunit, alpha isoform
3 [Homo sapiens]
Length = 341
Score = 224 bits (572), Expect = 1e-58
Identities = 112/280 (40%), Positives = 171/280 (61%), Gaps = 13/280 (4%)
Query: 52 KEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANT 111
K +L E+ + + I + LL+++AP+ +CGDIHGQ++DL++LFE GG P +
Sbjct: 37 KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 96
Query: 112 RYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYS 171
YLFLGDYVDRG S+E + L A KI YP+ FLLRGNHEC + + F ECK +Y+
Sbjct: 97 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 156
Query: 172 ERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDIL 231
+++ D F+CLP+AA+++++ C HGGLSP++ +++ IR++ R + P G +CD+L
Sbjct: 157 IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 216
Query: 232 WSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMY 291
WSDP +K + + N RG S+ + V +FL ++L I RAH+ + GY +
Sbjct: 217 WSDP------DKDVQGWGEND-RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFF 269
Query: 292 RKSQTTGFPSLITIFSAPNYLDVYNNKVTEMLVNVLNICS 331
K Q L+T+FSAPNY ++N M V+ +CS
Sbjct: 270 AKRQ------LVTLFSAPNYCGEFDNAGAMMSVDETLMCS 303
>gi|4506003 protein phosphatase 1, catalytic subunit, alpha isoform
1 [Homo sapiens]
Length = 330
Score = 224 bits (572), Expect = 1e-58
Identities = 112/280 (40%), Positives = 171/280 (61%), Gaps = 13/280 (4%)
Query: 52 KEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANT 111
K +L E+ + + I + LL+++AP+ +CGDIHGQ++DL++LFE GG P +
Sbjct: 26 KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 85
Query: 112 RYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYS 171
YLFLGDYVDRG S+E + L A KI YP+ FLLRGNHEC + + F ECK +Y+
Sbjct: 86 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 145
Query: 172 ERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDIL 231
+++ D F+CLP+AA+++++ C HGGLSP++ +++ IR++ R + P G +CD+L
Sbjct: 146 IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 205
Query: 232 WSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMY 291
WSDP +K + + N RG S+ + V +FL ++L I RAH+ + GY +
Sbjct: 206 WSDP------DKDVQGWGEND-RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFF 258
Query: 292 RKSQTTGFPSLITIFSAPNYLDVYNNKVTEMLVNVLNICS 331
K Q L+T+FSAPNY ++N M V+ +CS
Sbjct: 259 AKRQ------LVTLFSAPNYCGEFDNAGAMMSVDETLMCS 292
>gi|46249376 protein phosphatase 1, catalytic subunit, beta isoform
1 [Homo sapiens]
Length = 327
Score = 220 bits (561), Expect = 2e-57
Identities = 116/302 (38%), Positives = 177/302 (58%), Gaps = 21/302 (6%)
Query: 38 DGKPRVDILKAHLM--------KEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCG 89
DG+ VD L L+ K ++ E+ + + I + LL+++AP+ +CG
Sbjct: 3 DGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICG 62
Query: 90 DIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRG 149
DIHGQ+ DL++LFE GG P YLFLGDYVDRG S+E + L A KI YP+ FLLRG
Sbjct: 63 DIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRG 122
Query: 150 NHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTL 209
NHEC + + F ECK +++ +++ D F+CLP+AA+++++ C HGGLSP++ ++
Sbjct: 123 NHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSM 182
Query: 210 DDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFL 269
+ IR++ R + P G +CD+LWSDP +K + + N RG S+ + V +FL
Sbjct: 183 EQIRRIMRPTDVPDTGLLCDLLWSDP------DKDVQGWGEND-RGVSFTFGADVVSKFL 235
Query: 270 QHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVTEMLVNVLNI 329
++L I RAH+ + GY + K Q L+T+FSAPNY ++N M V+ +
Sbjct: 236 NRHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGGMMSVDETLM 289
Query: 330 CS 331
CS
Sbjct: 290 CS 291
>gi|4506005 protein phosphatase 1, catalytic subunit, beta isoform 1
[Homo sapiens]
Length = 327
Score = 220 bits (561), Expect = 2e-57
Identities = 116/302 (38%), Positives = 177/302 (58%), Gaps = 21/302 (6%)
Query: 38 DGKPRVDILKAHLM--------KEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCG 89
DG+ VD L L+ K ++ E+ + + I + LL+++AP+ +CG
Sbjct: 3 DGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICG 62
Query: 90 DIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRG 149
DIHGQ+ DL++LFE GG P YLFLGDYVDRG S+E + L A KI YP+ FLLRG
Sbjct: 63 DIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRG 122
Query: 150 NHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTL 209
NHEC + + F ECK +++ +++ D F+CLP+AA+++++ C HGGLSP++ ++
Sbjct: 123 NHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSM 182
Query: 210 DDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFL 269
+ IR++ R + P G +CD+LWSDP +K + + N RG S+ + V +FL
Sbjct: 183 EQIRRIMRPTDVPDTGLLCDLLWSDP------DKDVQGWGEND-RGVSFTFGADVVSKFL 235
Query: 270 QHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVTEMLVNVLNI 329
++L I RAH+ + GY + K Q L+T+FSAPNY ++N M V+ +
Sbjct: 236 NRHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGGMMSVDETLM 289
Query: 330 CS 331
CS
Sbjct: 290 CS 291
>gi|57222565 protein phosphatase 2, catalytic subunit, beta isoform
[Homo sapiens]
Length = 309
Score = 220 bits (560), Expect = 2e-57
Identities = 117/258 (45%), Positives = 155/258 (60%), Gaps = 15/258 (5%)
Query: 55 RLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYL 114
+L E+ + + IL +E N+ ++ PVTVCGD+HGQF DLM+LF +GG +T YL
Sbjct: 22 QLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 81
Query: 115 FLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKY-SER 173
F+GDYVDRGY+S+E V L ALK+ YP+ + +LRGNHE R +T+ + F EC KY +
Sbjct: 82 FMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNAN 141
Query: 174 VYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWS 233
V+ D FD LPL AL++ Q C+HGGLSP I+TLD IR LDR +E P GPMCD+LWS
Sbjct: 142 VWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWS 201
Query: 234 DPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRK 293
DP +D G + RG Y + F N L + RAH+ GY
Sbjct: 202 DP-DDRGGWGI-------SPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHD 253
Query: 294 SQTTGFPSLITIFSAPNY 311
+++TIFSAPNY
Sbjct: 254 R------NVVTIFSAPNY 265
>gi|4758952 protein phosphatase 2, catalytic subunit, beta isoform
[Homo sapiens]
Length = 309
Score = 220 bits (560), Expect = 2e-57
Identities = 117/258 (45%), Positives = 155/258 (60%), Gaps = 15/258 (5%)
Query: 55 RLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYL 114
+L E+ + + IL +E N+ ++ PVTVCGD+HGQF DLM+LF +GG +T YL
Sbjct: 22 QLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 81
Query: 115 FLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKY-SER 173
F+GDYVDRGY+S+E V L ALK+ YP+ + +LRGNHE R +T+ + F EC KY +
Sbjct: 82 FMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNAN 141
Query: 174 VYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWS 233
V+ D FD LPL AL++ Q C+HGGLSP I+TLD IR LDR +E P GPMCD+LWS
Sbjct: 142 VWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWS 201
Query: 234 DPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRK 293
DP +D G + RG Y + F N L + RAH+ GY
Sbjct: 202 DP-DDRGGWGI-------SPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHD 253
Query: 294 SQTTGFPSLITIFSAPNY 311
+++TIFSAPNY
Sbjct: 254 R------NVVTIFSAPNY 265
>gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens]
Length = 307
Score = 219 bits (558), Expect = 4e-57
Identities = 113/257 (43%), Positives = 158/257 (61%), Gaps = 15/257 (5%)
Query: 56 LEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLF 115
++ES + + IL +E N+ +D+PVTVCGDIHGQF+DL +LF VGG T YLF
Sbjct: 20 IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLF 79
Query: 116 LGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKY-SERV 174
+GD+VDRG++S+E L L ALK+ YP + L+RGNHE R +T+ + F EC KY S V
Sbjct: 80 MGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTV 139
Query: 175 YDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSD 234
+ C + FD L L+A+++ + CVHGGLSP I TLD IR +DR +E P GPMCD+LWSD
Sbjct: 140 WRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSD 199
Query: 235 PLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKS 294
P + G + RG Y + V +F N++ I RAH+ GY+ +
Sbjct: 200 PEDTTG--------WGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNE 251
Query: 295 QTTGFPSLITIFSAPNY 311
+++T++SAPNY
Sbjct: 252 ------TVLTVWSAPNY 262
>gi|4506017 protein phosphatase 2, catalytic subunit, alpha isoform
[Homo sapiens]
Length = 309
Score = 218 bits (554), Expect = 1e-56
Identities = 117/258 (45%), Positives = 154/258 (59%), Gaps = 15/258 (5%)
Query: 55 RLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYL 114
+L ES + + IL +E N+ ++ PVTVCGD+HGQF DLM+LF +GG +T YL
Sbjct: 22 QLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 81
Query: 115 FLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKY-SER 173
F+GDYVDRGY+S+E V L ALK+ Y + + +LRGNHE R +T+ + F EC KY +
Sbjct: 82 FMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNAN 141
Query: 174 VYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWS 233
V+ D FD LPL AL++ Q C+HGGLSP I+TLD IR LDR +E P GPMCD+LWS
Sbjct: 142 VWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWS 201
Query: 234 DPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRK 293
DP +D G + RG Y + F N L + RAH+ GY
Sbjct: 202 DP-DDRGGWGI-------SPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHD 253
Query: 294 SQTTGFPSLITIFSAPNY 311
+++TIFSAPNY
Sbjct: 254 R------NVVTIFSAPNY 265
>gi|4506029 protein phosphatase 6, catalytic subunit isoform b [Homo
sapiens]
Length = 305
Score = 212 bits (540), Expect = 5e-55
Identities = 114/274 (41%), Positives = 159/274 (58%), Gaps = 15/274 (5%)
Query: 56 LEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLF 115
L E+ R+ +L +E N+ + PVTVCGDIHGQF+DL +LF GG +T Y+F
Sbjct: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIF 78
Query: 116 LGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKY-SERV 174
+GD+VDRGY+S+E YL ALK +P + LLRGNHE R +T+ + F EC+ KY +
Sbjct: 79 MGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 138
Query: 175 YDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSD 234
+ C FD L +AAL+++Q LCVHGGLSP+I TLD IR ++R +E P G CD++WSD
Sbjct: 139 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 198
Query: 235 PLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKS 294
P ED + RG + + EF+ NNL I RAH+ GY+
Sbjct: 199 P-EDVDTWAI-------SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDE 250
Query: 295 QTTGFPSLITIFSAPNYLDVYNNKVTEMLVNVLN 328
+ L+T++SAPNY N + M+ +N
Sbjct: 251 K------LVTVWSAPNYCYRCGNIASIMVFKDVN 278
>gi|183603929 protein phosphatase 6, catalytic subunit isoform a
[Homo sapiens]
Length = 342
Score = 211 bits (537), Expect = 1e-54
Identities = 111/259 (42%), Positives = 154/259 (59%), Gaps = 15/259 (5%)
Query: 71 ILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 130
+L +E N+ + PVTVCGDIHGQF+DL +LF GG +T Y+F+GD+VDRGY+S+E
Sbjct: 71 LLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETF 130
Query: 131 LYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKY-SERVYDACMDAFDCLPLAA 189
YL ALK +P + LLRGNHE R +T+ + F EC+ KY + + C FD L +AA
Sbjct: 131 TYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAA 190
Query: 190 LMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFT 249
L+++Q LCVHGGLSP+I TLD IR ++R +E P G CD++WSDP ED
Sbjct: 191 LIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP-EDVDTWAI----- 244
Query: 250 HNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAP 309
+ RG + + EF+ NNL I RAH+ GY+ + L+T++SAP
Sbjct: 245 --SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK------LVTVWSAP 296
Query: 310 NYLDVYNNKVTEMLVNVLN 328
NY N + M+ +N
Sbjct: 297 NYCYRCGNIASIMVFKDVN 315
>gi|45827798 protein phosphatase 1, catalytic subunit, alpha isoform
2 [Homo sapiens]
Length = 286
Score = 208 bits (530), Expect = 7e-54
Identities = 103/243 (42%), Positives = 152/243 (62%), Gaps = 13/243 (5%)
Query: 89 GDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLR 148
GDIHGQ++DL++LFE GG P + YLFLGDYVDRG S+E + L A KI YP+ FLLR
Sbjct: 19 GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 78
Query: 149 GNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINT 208
GNHEC + + F ECK +Y+ +++ D F+CLP+AA+++++ C HGGLSP++ +
Sbjct: 79 GNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQS 138
Query: 209 LDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEF 268
++ IR++ R + P G +CD+LWSDP +K + + N RG S+ + V +F
Sbjct: 139 MEQIRRIMRPTDVPDQGLLCDLLWSDP------DKDVQGWGEND-RGVSFTFGAEVVAKF 191
Query: 269 LQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVTEMLVNVLN 328
L ++L I RAH+ + GY + K Q L+T+FSAPNY ++N M V+
Sbjct: 192 LHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGAMMSVDETL 245
Query: 329 ICS 331
+CS
Sbjct: 246 MCS 248
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 203 bits (517), Expect = 2e-52
Identities = 112/292 (38%), Positives = 167/292 (57%), Gaps = 23/292 (7%)
Query: 38 DGKPRVDILKAHLM---KEGRLEESVALRIITEGASILRQEKNLLDIDAP----VTVCGD 90
DGK + +K + + +L A +I+ + +L + L++ +TVCGD
Sbjct: 183 DGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGD 242
Query: 91 IHGQFFDLMKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRG 149
HGQF+DL+ +FE+ G P+ T Y+F GD+VDRG FS+E +L L+ K+LYP LLRG
Sbjct: 243 THGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRG 302
Query: 150 NHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEIN-T 208
NHE ++ + + F+ E K KY+ ++Y+ + F+ LPLA +N + L +HGGL E T
Sbjct: 303 NHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVT 362
Query: 209 LDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEF 268
LDDIRK++R ++PP GPMCD+LWSDP G ++ RG S + F
Sbjct: 363 LDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISK--------RGVSCQFGPDVTKAF 414
Query: 269 LQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVT 320
L+ NNL I+R+HE + GY + + +T+FSAPNY D NK +
Sbjct: 415 LEENNLDYIIRSHEVKAEGYEVAHGGR------CVTVFSAPNYCDQMGNKAS 460
>gi|183603931 protein phosphatase 6, catalytic subunit isoform c
[Homo sapiens]
Length = 283
Score = 176 bits (446), Expect = 4e-44
Identities = 104/274 (37%), Positives = 143/274 (52%), Gaps = 37/274 (13%)
Query: 56 LEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLF 115
L E+ R+ +L +E N+ + PVTVCGDIHGQ
Sbjct: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--------------------- 57
Query: 116 LGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSE-RV 174
GD+VDRGY+S+E YL ALK +P + LLRGNHE R +T+ + F EC+ KY
Sbjct: 58 -GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 116
Query: 175 YDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSD 234
+ C FD L +AAL+++Q LCVHGGLSP+I TLD IR ++R +E P G CD++WSD
Sbjct: 117 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 176
Query: 235 PLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKS 294
P ED + RG + + EF+ NNL I RAH+ GY+
Sbjct: 177 P-EDVDTWAI-------SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDE 228
Query: 295 QTTGFPSLITIFSAPNYLDVYNNKVTEMLVNVLN 328
+ L+T++SAPNY N + M+ +N
Sbjct: 229 K------LVTVWSAPNYCYRCGNIASIMVFKDVN 256
>gi|23312374 protein phosphatase with EF hand calcium-binding domain
1 isoform 1b [Homo sapiens]
Length = 625
Score = 122 bits (307), Expect = 5e-28
Identities = 86/300 (28%), Positives = 142/300 (47%), Gaps = 38/300 (12%)
Query: 43 VDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAP----VTVCGDIHGQFFDL 98
+D+L ++ L L ++ E +L+Q N I VT+CGD+HG+ DL
Sbjct: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
Query: 99 MKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLT 157
+F G P+ Y+F GD+VDRG SIE ++ L ++YP L L RGNHE +
Sbjct: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
Query: 158 EYFTFKQECKIKY---SERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRK 214
+ F +E KY +R+ + + LP+ +++ + L +HGG+S E L+ + +
Sbjct: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHR 299
Query: 215 LDRFKE-----PPA-----------YGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSY 258
++R K PP + + DILWSDP + + NT RG
Sbjct: 300 VERNKMKSVLIPPTETNRDHDTDSKHNKIIDILWSDP-------RGKNGCFPNTCRGGGC 352
Query: 259 FYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNK 318
++ + L L ++R+HE + GY + + ++TIFSA NY + +N+
Sbjct: 353 YFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGK------VVTIFSASNYYEEGSNR 406
>gi|23312380 protein phosphatase with EF hand calcium-binding domain
1 isoform 1 [Homo sapiens]
Length = 653
Score = 111 bits (278), Expect = 1e-24
Identities = 88/328 (26%), Positives = 144/328 (43%), Gaps = 66/328 (20%)
Query: 43 VDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAP----VTVCGDIHGQFFDL 98
+D+L ++ L L ++ E +L+Q N I VT+CGD+HG+ DL
Sbjct: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
Query: 99 MKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLT 157
+F G P+ Y+F GD+VDRG SIE ++ L ++YP L L RGNHE +
Sbjct: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
Query: 158 EYFTFKQECKIKY---SERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRK 214
+ F +E KY +R+ + + LP+ +++ + L +HGG+S E L+ + +
Sbjct: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHR 299
Query: 215 LDRFKE-----PP---------------------AYG------------------PMCDI 230
++R K PP A+G + DI
Sbjct: 300 VERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDI 359
Query: 231 LWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRM 290
LWSDP + + NT RG ++ + L L ++R+HE + GY +
Sbjct: 360 LWSDP-------RGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEI 412
Query: 291 YRKSQTTGFPSLITIFSAPNYLDVYNNK 318
+ ++TIFSA NY + +N+
Sbjct: 413 CHDGK------VVTIFSASNYYEEGSNR 434
>gi|239752750 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 384
Score = 107 bits (268), Expect = 2e-23
Identities = 76/245 (31%), Positives = 108/245 (44%), Gaps = 68/245 (27%)
Query: 67 EGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFS 126
E IL +E N ++ PVTV GD HGQ GDY+DRGY+S
Sbjct: 183 EAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRGYYS 220
Query: 127 IECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLP 186
IE V+ L A+K+ Y + + +L NHE R +T+ + +EC K+ D
Sbjct: 221 IEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGDG--------- 271
Query: 187 LAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQE 246
Q C+HGGLSP ++TL IR L+ ++ P GPM D+L+SDP + T E
Sbjct: 272 -------QLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP----DDHDTPE 320
Query: 247 HFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIF 306
F H + L + RAH+ G+ +++ IF
Sbjct: 321 TFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVVAIF 354
Query: 307 SAPNY 311
S PNY
Sbjct: 355 STPNY 359
>gi|239747318 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 254
Score = 107 bits (268), Expect = 2e-23
Identities = 76/245 (31%), Positives = 108/245 (44%), Gaps = 68/245 (27%)
Query: 67 EGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFS 126
E IL +E N ++ PVTV GD HGQ GDY+DRGY+S
Sbjct: 62 EAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRGYYS 99
Query: 127 IECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLP 186
IE V+ L A+K+ Y + + +L NHE R +T+ + +EC K+ D
Sbjct: 100 IEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGDG--------- 150
Query: 187 LAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQE 246
Q C+HGGLSP ++TL IR L+ ++ P GPM D+L+SDP + T E
Sbjct: 151 -------QLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP----DDHDTPE 199
Query: 247 HFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIF 306
F H + L + RAH+ G+ +++ IF
Sbjct: 200 TFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVVAIF 233
Query: 307 SAPNY 311
S PNY
Sbjct: 234 STPNY 238
>gi|239741140 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 254
Score = 107 bits (268), Expect = 2e-23
Identities = 76/245 (31%), Positives = 108/245 (44%), Gaps = 68/245 (27%)
Query: 67 EGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFS 126
E IL +E N ++ PVTV GD HGQ GDY+DRGY+S
Sbjct: 62 EAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRGYYS 99
Query: 127 IECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLP 186
IE V+ L A+K+ Y + + +L NHE R +T+ + +EC K+ D
Sbjct: 100 IEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGDG--------- 150
Query: 187 LAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQE 246
Q C+HGGLSP ++TL IR L+ ++ P GPM D+L+SDP + T E
Sbjct: 151 -------QLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP----DDHDTPE 199
Query: 247 HFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIF 306
F H + L + RAH+ G+ +++ IF
Sbjct: 200 TFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVVAIF 233
Query: 307 SAPNY 311
S PNY
Sbjct: 234 STPNY 238
>gi|23312386 serine/threonine protein phosphatase with EF-hand
motifs 2 [Homo sapiens]
Length = 753
Score = 101 bits (251), Expect = 2e-21
Identities = 64/183 (34%), Positives = 103/183 (56%), Gaps = 10/183 (5%)
Query: 45 ILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDA----PVTVCGDIHGQFFDLMK 100
+++A +K+ +L L ++ E L Q N+ + +TVCGD+HGQ DL+
Sbjct: 131 LVEAFRLKQ-QLHARYVLNLLYETKKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIF 189
Query: 101 LFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEY 159
+F G P+ R Y+F GD+VDRG S+E ++ L+A ++YPK L RGNHE +
Sbjct: 190 IFYKNGLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLR 249
Query: 160 FTFKQECKIKY---SERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLD 216
+ F +E KY + + D F LPLA L++++ L +HGG+S +I L+ + K++
Sbjct: 250 YGFTKEVMNKYKVHGKEILRTLQDVFCWLPLATLIDEKVLILHGGVS-DITDLELLDKIE 308
Query: 217 RFK 219
R K
Sbjct: 309 RSK 311
Score = 52.8 bits (125), Expect = 7e-07
Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 13/90 (14%)
Query: 229 DILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGY 288
DILWSDP+ QE NT+RG ++ + LQ N+ ++R+HE + GY
Sbjct: 443 DILWSDPM-------AQEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGY 495
Query: 289 RMYRKSQTTGFPSLITIFSAPNYLDVYNNK 318
+ ++TIFSA NY +V +N+
Sbjct: 496 EFCHNRK------VLTIFSASNYYEVGSNR 519
>gi|23312378 protein phosphatase with EF hand calcium-binding domain
1 isoform 3 [Homo sapiens]
Length = 591
Score = 95.1 bits (235), Expect = 1e-19
Identities = 74/284 (26%), Positives = 123/284 (43%), Gaps = 40/284 (14%)
Query: 43 VDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAP----VTVCGDIHGQFFDL 98
+D+L ++ L L ++ E +L+Q N I VT+CGD+HG+ DL
Sbjct: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
Query: 99 MKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLT 157
+F G P+ Y+F GD+VDRG SIE ++ L ++YP L L RGNHE +
Sbjct: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
Query: 158 EYFTFKQECKIKY---SERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRK 214
+ F +E KY +R+ + + LP+ +++ + L +HGG+S E L+ + +
Sbjct: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHR 299
Query: 215 LDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNL 274
++R K P E ++H T + +HN +
Sbjct: 300 VERNKMKSVLIP-------------PTETNRDHDTDS------------------KHNKV 328
Query: 275 LSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNK 318
AH + ++TIFSA NY + +N+
Sbjct: 329 GVTFNAHGRIKTNGSPTEHLTEHEWEQVVTIFSASNYYEEGSNR 372
>gi|156104878 glutaminase [Homo sapiens]
Length = 669
Score = 32.7 bits (73), Expect = 0.73
Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 4/48 (8%)
Query: 221 PPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEF 268
P G MC WS PL+ GN HF H+ V C+ F++Y + F
Sbjct: 493 PNVMGMMC---WSPPLDKMGNSVKGIHFCHDLVSLCN-FHNYDNLRHF 536
>gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens]
Length = 705
Score = 29.6 bits (65), Expect = 6.1
Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 8/97 (8%)
Query: 269 LQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVTEMLVNVLN 328
LQ L AHE D+G K+ +L+ S P+ + ++ E+L ++N
Sbjct: 220 LQEKADLQEKEAHELLDSG-----KNTAVTTKNLLETLSKPDQIPLFYAGGIEILTEMIN 274
Query: 329 ICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMA 365
C++ L +GF + + EVIR G A
Sbjct: 275 ECTEQTLFRMHNGF---SIISDNEVIRRCFSTAGNDA 308
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,308,768
Number of Sequences: 37866
Number of extensions: 817111
Number of successful extensions: 1992
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1871
Number of HSP's gapped (non-prelim): 59
length of query: 469
length of database: 18,247,518
effective HSP length: 106
effective length of query: 363
effective length of database: 14,233,722
effective search space: 5166841086
effective search space used: 5166841086
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.