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Search of human proteins with 194306623
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194306623 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
(745 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194306623 immunoglobulin superfamily containing leucine-rich ... 1512 0.0
gi|194306621 immunoglobulin superfamily containing leucine-rich ... 1512 0.0
gi|39930401 immunoglobulin superfamily containing leucine-rich r... 1512 0.0
gi|194306618 immunoglobulin superfamily containing leucine-rich ... 1512 0.0
gi|41582239 immunoglobulin superfamily containing leucine-rich r... 383 e-106
gi|5031809 immunoglobulin superfamily containing leucine-rich re... 383 e-106
gi|13375646 leucine rich repeat and fibronectin type III domain ... 123 7e-28
gi|27363458 leucine rich repeat and fibronectin type III domain ... 122 2e-27
gi|229089140 leucine rich repeat containing 24 [Homo sapiens] 118 2e-26
gi|188528675 slit homolog 1 [Homo sapiens] 116 7e-26
gi|4759146 slit homolog 2 [Homo sapiens] 115 2e-25
gi|61966761 leucine rich repeat containing 26 [Homo sapiens] 115 2e-25
gi|11321571 slit homolog 3 [Homo sapiens] 114 4e-25
gi|193083136 leucine-rich repeat, immunoglobulin-like and transm... 114 4e-25
gi|109150416 peroxidasin [Homo sapiens] 110 6e-24
gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens] 107 3e-23
gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens] 107 3e-23
gi|139948432 adlican [Homo sapiens] 107 5e-23
gi|14149694 retina specific protein PAL [Homo sapiens] 105 2e-22
gi|10190722 leucine-rich repeats and transmembrane domains 1 [Ho... 104 3e-22
gi|31542244 leucine rich repeat and fibronectin type III domain ... 99 1e-20
gi|51317373 netrin-G1 ligand [Homo sapiens] 98 3e-20
gi|194440719 chondroadherin-like [Homo sapiens] 95 2e-19
gi|84781739 leucine-rich repeats and transmembrane domains 2 [Ho... 95 3e-19
gi|113423021 PREDICTED: similar to hCG1820409 [Homo sapiens] 93 8e-19
gi|113422497 PREDICTED: similar to hCG1820409 [Homo sapiens] 93 8e-19
gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens] 93 8e-19
gi|59823631 G protein-coupled receptor 125 [Homo sapiens] 93 8e-19
gi|157694513 leucine-rich repeat-containing G protein-coupled re... 93 1e-18
gi|62988340 leucine rich repeat containing 22 [Homo sapiens] 92 2e-18
>gi|194306623 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 1512 bits (3915), Expect = 0.0
Identities = 745/745 (100%), Positives = 745/745 (100%)
Query: 1 MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA 60
MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA
Sbjct: 1 MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA 60
Query: 61 NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR 120
NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR
Sbjct: 61 NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR 120
Query: 121 NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH 180
NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH
Sbjct: 121 NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH 180
Query: 181 NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE 240
NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE
Sbjct: 181 NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE 240
Query: 241 PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG 300
PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG
Sbjct: 241 PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG 300
Query: 301 EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE 360
EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE
Sbjct: 301 EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE 360
Query: 361 LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ 420
LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ
Sbjct: 361 LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ 420
Query: 421 GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK 480
GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK
Sbjct: 421 GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK 480
Query: 481 PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA 540
PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA
Sbjct: 481 PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA 540
Query: 541 VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL 600
VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL
Sbjct: 541 VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL 600
Query: 601 LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA 660
LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA
Sbjct: 601 LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA 660
Query: 661 GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS 720
GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS
Sbjct: 661 GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS 720
Query: 721 DRLPLGAEAVNIAQEINGNYRQTAG 745
DRLPLGAEAVNIAQEINGNYRQTAG
Sbjct: 721 DRLPLGAEAVNIAQEINGNYRQTAG 745
>gi|194306621 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 1512 bits (3915), Expect = 0.0
Identities = 745/745 (100%), Positives = 745/745 (100%)
Query: 1 MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA 60
MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA
Sbjct: 1 MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA 60
Query: 61 NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR 120
NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR
Sbjct: 61 NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR 120
Query: 121 NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH 180
NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH
Sbjct: 121 NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH 180
Query: 181 NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE 240
NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE
Sbjct: 181 NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE 240
Query: 241 PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG 300
PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG
Sbjct: 241 PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG 300
Query: 301 EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE 360
EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE
Sbjct: 301 EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE 360
Query: 361 LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ 420
LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ
Sbjct: 361 LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ 420
Query: 421 GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK 480
GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK
Sbjct: 421 GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK 480
Query: 481 PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA 540
PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA
Sbjct: 481 PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA 540
Query: 541 VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL 600
VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL
Sbjct: 541 VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL 600
Query: 601 LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA 660
LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA
Sbjct: 601 LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA 660
Query: 661 GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS 720
GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS
Sbjct: 661 GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS 720
Query: 721 DRLPLGAEAVNIAQEINGNYRQTAG 745
DRLPLGAEAVNIAQEINGNYRQTAG
Sbjct: 721 DRLPLGAEAVNIAQEINGNYRQTAG 745
>gi|39930401 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 1512 bits (3915), Expect = 0.0
Identities = 745/745 (100%), Positives = 745/745 (100%)
Query: 1 MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA 60
MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA
Sbjct: 1 MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA 60
Query: 61 NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR 120
NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR
Sbjct: 61 NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR 120
Query: 121 NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH 180
NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH
Sbjct: 121 NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH 180
Query: 181 NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE 240
NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE
Sbjct: 181 NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE 240
Query: 241 PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG 300
PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG
Sbjct: 241 PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG 300
Query: 301 EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE 360
EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE
Sbjct: 301 EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE 360
Query: 361 LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ 420
LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ
Sbjct: 361 LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ 420
Query: 421 GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK 480
GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK
Sbjct: 421 GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK 480
Query: 481 PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA 540
PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA
Sbjct: 481 PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA 540
Query: 541 VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL 600
VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL
Sbjct: 541 VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL 600
Query: 601 LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA 660
LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA
Sbjct: 601 LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA 660
Query: 661 GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS 720
GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS
Sbjct: 661 GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS 720
Query: 721 DRLPLGAEAVNIAQEINGNYRQTAG 745
DRLPLGAEAVNIAQEINGNYRQTAG
Sbjct: 721 DRLPLGAEAVNIAQEINGNYRQTAG 745
>gi|194306618 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 1512 bits (3915), Expect = 0.0
Identities = 745/745 (100%), Positives = 745/745 (100%)
Query: 1 MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA 60
MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA
Sbjct: 1 MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA 60
Query: 61 NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR 120
NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR
Sbjct: 61 NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR 120
Query: 121 NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH 180
NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH
Sbjct: 121 NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH 180
Query: 181 NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE 240
NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE
Sbjct: 181 NPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAE 240
Query: 241 PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG 300
PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG
Sbjct: 241 PPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEG 300
Query: 301 EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE 360
EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE
Sbjct: 301 EGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNE 360
Query: 361 LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ 420
LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ
Sbjct: 361 LGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQ 420
Query: 421 GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK 480
GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK
Sbjct: 421 GLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELK 480
Query: 481 PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA 540
PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA
Sbjct: 481 PHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAA 540
Query: 541 VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL 600
VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL
Sbjct: 541 VQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFL 600
Query: 601 LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA 660
LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA
Sbjct: 601 LVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPA 660
Query: 661 GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS 720
GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS
Sbjct: 661 GGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYS 720
Query: 721 DRLPLGAEAVNIAQEINGNYRQTAG 745
DRLPLGAEAVNIAQEINGNYRQTAG
Sbjct: 721 DRLPLGAEAVNIAQEINGNYRQTAG 745
>gi|41582239 immunoglobulin superfamily containing leucine-rich
repeat [Homo sapiens]
Length = 428
Score = 383 bits (983), Expect = e-106
Identities = 217/426 (50%), Positives = 260/426 (61%), Gaps = 50/426 (11%)
Query: 1 MFPLRALWLVWALL-GVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLS 59
M L LW WALL G+A +CPEPC C +KY Q ADCAY++L VP G PANVTTLSLS
Sbjct: 1 MQELHLLW--WALLLGLAQACPEPCDCGEKYGFQIADCAYRDLESVPPGFPANVTTLSLS 58
Query: 60 ANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDL 119
AN++ L GAF +V + SLWLAHNE+RTV GALA LS LK+LDLSHN IS F WSDL
Sbjct: 59 ANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFAWSDL 118
Query: 120 RNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLY 179
NLSALQLLKM+ N L +PRDA +L LRSL++N+NRL TLA GTF L+ALSHLQ+
Sbjct: 119 HNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQIN 178
Query: 180 HNPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSA 239
NPF C CG+VWL+ WA +T VS+PE D+IAC SP L+G P+ RLP LPC+ PSV LS
Sbjct: 179 ENPFDCTCGIVWLKTWALTTAVSIPEQDNIACTSPHVLKGTPLSRLPPLPCSAPSVQLSY 238
Query: 240 EPPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEE 299
+P + G LR G LHC DG P P+L W +QIP G V + P VG
Sbjct: 239 QPSQD--GAELRPGFVLALHCDVDGQPAPQLHWHIQIPSGIVEITSP-------NVGT-- 287
Query: 300 GEGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHN 359
DG L P P + PRF A ANGSLL+P E G Y+C A N
Sbjct: 288 -----DGRAL-----------PGTPVASSQPRFQAFANGSLLIPDFGKLEEGTYSCLATN 331
Query: 360 ELGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERK---STAKGRG-----NSVLPS 411
ELG+ +S+ VA+A PG GGE T R+ +G+G N V PS
Sbjct: 332 ELGSAESSVDVALA-------TPGEGGE-----DTLGRRFHGKAVEGKGCYTVDNEVQPS 379
Query: 412 KPEGKI 417
PE +
Sbjct: 380 GPEDNV 385
>gi|5031809 immunoglobulin superfamily containing leucine-rich
repeat [Homo sapiens]
Length = 428
Score = 383 bits (983), Expect = e-106
Identities = 217/426 (50%), Positives = 260/426 (61%), Gaps = 50/426 (11%)
Query: 1 MFPLRALWLVWALL-GVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLS 59
M L LW WALL G+A +CPEPC C +KY Q ADCAY++L VP G PANVTTLSLS
Sbjct: 1 MQELHLLW--WALLLGLAQACPEPCDCGEKYGFQIADCAYRDLESVPPGFPANVTTLSLS 58
Query: 60 ANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDL 119
AN++ L GAF +V + SLWLAHNE+RTV GALA LS LK+LDLSHN IS F WSDL
Sbjct: 59 ANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFAWSDL 118
Query: 120 RNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLY 179
NLSALQLLKM+ N L +PRDA +L LRSL++N+NRL TLA GTF L+ALSHLQ+
Sbjct: 119 HNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQIN 178
Query: 180 HNPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSA 239
NPF C CG+VWL+ WA +T VS+PE D+IAC SP L+G P+ RLP LPC+ PSV LS
Sbjct: 179 ENPFDCTCGIVWLKTWALTTAVSIPEQDNIACTSPHVLKGTPLSRLPPLPCSAPSVQLSY 238
Query: 240 EPPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEE 299
+P + G LR G LHC DG P P+L W +QIP G V + P VG
Sbjct: 239 QPSQD--GAELRPGFVLALHCDVDGQPAPQLHWHIQIPSGIVEITSP-------NVGT-- 287
Query: 300 GEGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHN 359
DG L P P + PRF A ANGSLL+P E G Y+C A N
Sbjct: 288 -----DGRAL-----------PGTPVASSQPRFQAFANGSLLIPDFGKLEEGTYSCLATN 331
Query: 360 ELGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERK---STAKGRG-----NSVLPS 411
ELG+ +S+ VA+A PG GGE T R+ +G+G N V PS
Sbjct: 332 ELGSAESSVDVALA-------TPGEGGE-----DTLGRRFHGKAVEGKGCYTVDNEVQPS 379
Query: 412 KPEGKI 417
PE +
Sbjct: 380 GPEDNV 385
>gi|13375646 leucine rich repeat and fibronectin type III domain
containing 3 [Homo sapiens]
Length = 628
Score = 123 bits (308), Expect = 7e-28
Identities = 111/384 (28%), Positives = 158/384 (41%), Gaps = 82/384 (21%)
Query: 42 LREVPEGLPANVTTLS---LSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVL 98
+R V G A++ L L N++T L G + + L L++N++ + GAL
Sbjct: 95 IRHVAAGAFADLRALRALHLDGNRLTSLGEGQLRGLVNLRHLILSNNQLAALAAGALDDC 154
Query: 99 SQ-LKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNN 157
++ L++LDLS+N + PW L L + L ++HN L S+P A L L L + +N
Sbjct: 155 AETLEDLDLSYNNLEQLPWEALGRLGNVNTLGLDHNLLASVPAGAFSRLHKLARLDMTSN 214
Query: 158 RLRTLAPG-TFDALSALSH----------LQLYHNPFHCGCGLVWLQAWAASTRVSLPEP 206
RL T+ P F L L+ L NP HC C LVWL+ A E
Sbjct: 215 RLTTIPPDPLFSRLPLLARPRGSPASALVLAFGGNPLHCNCELVWLRRLAR-------ED 267
Query: 207 DSIACASPPALQGVPVYRL--PALPCAPPSVHLSAEPPLEAPGTPLRAGLAFVLHCIADG 264
D ACASPPAL G + + C PP V PPL P AG L C A G
Sbjct: 268 DLEACASPPALGGRYFWAVGEEEFVCEPPVV-THRSPPLAVP-----AGRPAALRCRAVG 321
Query: 265 HPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEGEGEGDGDLLTQTQAQTPTPAPAWP 324
P PR++W + P G LL +
Sbjct: 322 DPEPRVRW----------VSP-------------------QGRLLGNSS----------- 341
Query: 325 APPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNELGANSTSIRVAVAATGPPKHA--- 381
R A NG+L + + + G++TC A N G + ++ + V PP+ A
Sbjct: 342 ------RARAFPNGTLELLVTEPGDGGIFTCIAANAAGEATAAVELTVGPPPPPQLANST 395
Query: 382 ---PGAGGEPDGQAPTSERKSTAK 402
P G+PD P S ++AK
Sbjct: 396 SCDPPRDGDPDALTPPSAASASAK 419
>gi|27363458 leucine rich repeat and fibronectin type III domain
containing 4 [Homo sapiens]
Length = 635
Score = 122 bits (305), Expect = 2e-27
Identities = 122/464 (26%), Positives = 175/464 (37%), Gaps = 121/464 (26%)
Query: 9 LVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLP------------------ 50
L+ L A +CP PC C + CA++ L VP +
Sbjct: 6 LLLLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALGP 65
Query: 51 ------ANVTTLSLSANKITVLRRGAFADVTQVTSLWL---------------------- 82
+ L+LS N IT + AF D+ + SL L
Sbjct: 66 PDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHL 125
Query: 83 --AHNEVRTVEPGALA-VLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLP 139
+ N++ + PGA L L++LDLS+N + PW+ + + AL L ++HN + +LP
Sbjct: 126 ILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALP 185
Query: 140 RDALGALPDLRSLRINNNRLRTLAPGTF-------DALSALSHLQLYHNPFHCGCGLVWL 192
A L L L + +NRL TLAP +A A L NP HC C L+WL
Sbjct: 186 PGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLVLSFSGNPLHCNCELLWL 245
Query: 193 QAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAEPPLEAPGTP--- 249
+ R++ P+ D CASPP L G + A P S EPPL A T
Sbjct: 246 R------RLARPD-DLETCASPPGLAGRYFW-------AVPEGEFSCEPPLIARHTQRLW 291
Query: 250 LRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEGEGEGDGDLL 309
+ G L C A G P P + W G DD +
Sbjct: 292 VLEGQRATLRCRALGDPAPTMHW----------------VGPDDRLVGN----------- 324
Query: 310 TQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNELGANSTSIR 369
+ R A NG+L + + A +AG YTC A N G + +
Sbjct: 325 -------------------SSRARAFPNGTLEIGVTGAGDAGGYTCIATNPAGEATARVE 365
Query: 370 VAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKP 413
+ V A ++ GG P + ++ A+G G L S+P
Sbjct: 366 LRVLALPHGGNSSAEGGRPGPSDIAASARTAAEGEG--TLESEP 407
>gi|229089140 leucine rich repeat containing 24 [Homo sapiens]
Length = 513
Score = 118 bits (296), Expect = 2e-26
Identities = 116/418 (27%), Positives = 156/418 (37%), Gaps = 75/418 (17%)
Query: 17 AGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRGAFADVTQ 76
A CP C C +C LR VP G+P TL L N I L GA A +
Sbjct: 20 AAGCPAACRCYSATV----ECGALRLRVVPLGIPPGTQTLFLQDNNIARLEPGALAPLAA 75
Query: 77 VTSLWLAHNEVRTVEPGALAV------------------------LSQLKNLDLSHNFIS 112
+ L+L +N +R +E GA L+QL+ L L+ N ++
Sbjct: 76 LRRLYLHNNSLRALEAGAFRAQPRLLELALTSNRLRGLRSGAFVGLAQLRVLYLAGNQLA 135
Query: 113 SFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSA 172
+L LQ L + N + L AL L L L ++ N+L T++ L++
Sbjct: 136 RLLDFTFLHLPRLQELHLQENSIELLEDQALAGLSSLALLDLSRNQLGTISREALQPLAS 195
Query: 173 LSHLQLYHNPFHCGCGLVWLQAW--AASTRVSLPEPDSIACASPP--ALQGVPVYRLPAL 228
L L+L NP+ C C L WL AW R+ I CA PP ALQ + +L
Sbjct: 196 LQVLRLTENPWRCDCALHWLGAWIKEGGQRLLTSRDRKIMCAEPPRLALQSLLDVSHSSL 255
Query: 229 PCAPPSVHLSAEPPLEAPGTPLRAGLAFVLHCIADGHPTPRLQW-QLQIPGGTVVLEPPV 287
C PPSVH+ PLE G + C A G+P P + W ++ P
Sbjct: 256 ICIPPSVHVQ---PLELTA---NLGEDLRVACQASGYPQPLVTWRKVPQPREGRPRAQAQ 309
Query: 288 LSGEDDGVGAEEGEGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSA 347
L G G+G G G L L+N ++
Sbjct: 310 LEGGLLGLGGHSASDTGSG-------------------------MLFLSN-------ITL 337
Query: 348 KEAGVYTCRAHNELGANSTSIRVAVAAT----GPPKHAPGAGGEPDGQAPTSERKSTA 401
AG Y C A N GA R+ V A+ P P P G P E S A
Sbjct: 338 AHAGKYECEASNAGGAARVPFRLLVNASRQQPQQPAQPPPPAARPAGSEPRPEAGSMA 395
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 116 bits (291), Expect = 7e-26
Identities = 62/204 (30%), Positives = 106/204 (51%), Gaps = 8/204 (3%)
Query: 20 CPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRR-GAFADVTQVT 78
CP C C +C+ +L ++PE +P + L L+ N+I++L G F +T +
Sbjct: 513 CPHKCRC----EANVVECSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLK 568
Query: 79 SLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSL 138
+ L++N+V +E GA + + L L+ N + S R L L+ L + +NR+ +
Sbjct: 569 KINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCI 628
Query: 139 PRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAAS 198
D+ L ++R L + +N++ T++PG FD L +LS L L NPF+C C L WL W
Sbjct: 629 HNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWLRK 688
Query: 199 TRVSLPEPDSIACASPPALQGVPV 222
++ P C +P L+ +P+
Sbjct: 689 RKIVTGNP---RCQNPDFLRQIPL 709
Score = 114 bits (286), Expect = 3e-25
Identities = 73/224 (32%), Positives = 108/224 (48%), Gaps = 35/224 (15%)
Query: 20 CPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRGAFADVTQVTS 79
CP+ CAC+D C+ K LR +P+G+P NVT L L N+ T++
Sbjct: 734 CPQECACLDTVVR----CSNKHLRALPKGIPKNVTELYLDGNQFTLV------------- 776
Query: 80 LWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLP 139
PG L+ L+ +DLS+N ISS S N+S L L +++N L +P
Sbjct: 777 ------------PGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIP 824
Query: 140 RDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAAST 199
A L LR L ++ N + TL G F +++LSHL + NP +C C L WL +W
Sbjct: 825 PLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLRWLSSW---V 881
Query: 200 RVSLPEPDSIACASPPALQGVPVYRLPA--LPC-APPSVHLSAE 240
+ EP CA P ++G + PA C PP++ + A+
Sbjct: 882 KTGYKEPGIARCAGPQDMEGKLLLTTPAKKFECQGPPTLAVQAK 925
Score = 112 bits (281), Expect = 1e-24
Identities = 69/201 (34%), Positives = 101/201 (50%), Gaps = 7/201 (3%)
Query: 17 AGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRGAFADVTQ 76
+GSCP C C ++ DC K L +P LP +T + L N I + GAF+ +
Sbjct: 279 SGSCPAMCTC----SNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRK 334
Query: 77 VTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLG 136
+ + L++N++ + P A L L +L L N I+ P L LQLL +N N++
Sbjct: 335 LRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKIN 394
Query: 137 SLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWA 196
+ DA L +L L + +N++++LA GTF +L A+ L L NPF C C L WL A
Sbjct: 395 CIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWL---A 451
Query: 197 ASTRVSLPEPDSIACASPPAL 217
R + E CASP L
Sbjct: 452 DFLRTNPIETSGARCASPRRL 472
Score = 97.8 bits (242), Expect = 3e-20
Identities = 71/248 (28%), Positives = 114/248 (45%), Gaps = 44/248 (17%)
Query: 7 LWLV-WAL---LGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANK 62
LWL+ WA LG A +CP C C DC L+ +P+ +P N L L+ N
Sbjct: 18 LWLLLWAAAWRLG-ASACPALCTCTGTTV----DCHGTGLQAIPKNIPRNTERLELNGNN 72
Query: 63 ITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNL 122
IT + + FA + Q+ L L N++ VE GA + +L+ L L+ N + P +N
Sbjct: 73 ITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNN 132
Query: 123 SALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDAL------------ 170
AL L ++ N + ++PR A DL++L+++ N++ + G F AL
Sbjct: 133 QALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNN 192
Query: 171 ------SALSHL------QLYHNPFHCGCGLVWLQAWAASTRVSLPEPDSIA----CASP 214
S+ +H+ +L+ N C C L WL W L + +I C+ P
Sbjct: 193 ITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQW-------LRQRPTIGLFTQCSGP 245
Query: 215 PALQGVPV 222
+L+G+ V
Sbjct: 246 ASLRGLNV 253
>gi|4759146 slit homolog 2 [Homo sapiens]
Length = 1529
Score = 115 bits (287), Expect = 2e-25
Identities = 68/198 (34%), Positives = 100/198 (50%), Gaps = 7/198 (3%)
Query: 20 CPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRGAFADVTQVTS 79
CP C C ++ DC K L E+P LP +T + L N I V+ GAF+ ++
Sbjct: 273 CPAACTC----SNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRR 328
Query: 80 LWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLP 139
+ L++N++ + P A L L +L L N I+ P S L +LQLL +N N++ L
Sbjct: 329 IDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLR 388
Query: 140 RDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAAST 199
DA L +L L + +N+L+T+A GTF L A+ + L NPF C C L WL + +
Sbjct: 389 VDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTN 448
Query: 200 RVSLPEPDSIACASPPAL 217
+ E C SP L
Sbjct: 449 PI---ETSGARCTSPRRL 463
Score = 113 bits (283), Expect = 6e-25
Identities = 63/205 (30%), Positives = 104/205 (50%), Gaps = 8/205 (3%)
Query: 19 SCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRR-GAFADVTQV 77
+CPE C C DC+ ++L ++PE +P L L+ N+ TVL G F + Q+
Sbjct: 505 ACPEKCRCEGTTV----DCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQL 560
Query: 78 TSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGS 137
+ ++N++ +E GA S + + L+ N + + + L +L+ L + NR+
Sbjct: 561 RKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITC 620
Query: 138 LPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAA 197
+ D+ L +R L + +N++ T+APG FD L +LS L L NPF+C C L WL W
Sbjct: 621 VGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLR 680
Query: 198 STRVSLPEPDSIACASPPALQGVPV 222
R+ P C P L+ +P+
Sbjct: 681 KKRIVTGNP---RCQKPYFLKEIPI 702
Score = 98.2 bits (243), Expect = 2e-20
Identities = 70/241 (29%), Positives = 106/241 (43%), Gaps = 35/241 (14%)
Query: 6 ALWLVWALLGVAG--SCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKI 63
+L LV A+L +CP C+C + DC LR VP +P N L L+ N I
Sbjct: 12 SLGLVLAILNKVAPQACPAQCSC----SGSTVDCHGLALRSVPRNIPRNTERLDLNGNNI 67
Query: 64 TVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLK--------------------- 102
T + + FA + + L L N++ T+E GA L +L+
Sbjct: 68 TRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTA 127
Query: 103 ---NLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRL 159
LDLS N I + P R ++ L++++N++ + A AL DL L +NNN +
Sbjct: 128 KLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNI 187
Query: 160 RTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAAS-TRVSLPEPDSIACASPPALQ 218
L+ +F+ + L +L+ N +C C L WL W RV L C P L+
Sbjct: 188 TRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLRQRPRVGL----YTQCMGPSHLR 243
Query: 219 G 219
G
Sbjct: 244 G 244
Score = 97.4 bits (241), Expect = 4e-20
Identities = 60/195 (30%), Positives = 88/195 (45%), Gaps = 32/195 (16%)
Query: 20 CPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRGAFADVTQVTS 79
CP C C+D C+ K L+ +P+G+P +VT L L N+ T++
Sbjct: 727 CPTECTCLDTVVR----CSNKGLKVLPKGIPRDVTELYLDGNQFTLV------------- 769
Query: 80 LWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLP 139
P L+ L +DLS+N IS+ N++ L L +++NRL +P
Sbjct: 770 ------------PKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIP 817
Query: 140 RDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAAST 199
L LR L ++ N + + G F+ LSALSHL + NP +C C + WL W S
Sbjct: 818 PRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSDWVKS- 876
Query: 200 RVSLPEPDSIACASP 214
EP CA P
Sbjct: 877 --EYKEPGIARCAGP 889
>gi|61966761 leucine rich repeat containing 26 [Homo sapiens]
Length = 334
Score = 115 bits (287), Expect = 2e-25
Identities = 81/224 (36%), Positives = 102/224 (45%), Gaps = 12/224 (5%)
Query: 8 WLVWALLGVAGS---------CPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSL 58
W VWA + S CPE C CV A C+ L VP GL + L L
Sbjct: 22 WPVWAQVSATASPSGSLGAPDCPEVCTCVPG---GLASCSALSLPAVPPGLSLRLRALLL 78
Query: 59 SANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSD 118
N++ L GAFA + L L N + +V A L L+ LDLS N + +
Sbjct: 79 DHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGT 138
Query: 119 LRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQL 178
L AL+ L + NRL L ALGALP LRSL + +N L LAPG L AL L L
Sbjct: 139 FAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHL 198
Query: 179 YHNPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPV 222
NP+ CGC L L AW + E +++ C P L P+
Sbjct: 199 RGNPWGCGCALRPLCAWLRRHPLPASEAETVLCVWPGRLTLSPL 242
>gi|11321571 slit homolog 3 [Homo sapiens]
Length = 1523
Score = 114 bits (284), Expect = 4e-25
Identities = 64/204 (31%), Positives = 102/204 (50%), Gaps = 8/204 (3%)
Query: 20 CPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRR-GAFADVTQVT 78
CPE C C DC+ ++L +P LP VT L L+ N+++VL G F + +
Sbjct: 505 CPEKCRCEGT----IVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLR 560
Query: 79 SLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSL 138
+ L++N+++ V GA + ++ L L+ N + + R LS L+ L + N +G +
Sbjct: 561 KINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCV 620
Query: 139 PRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAAS 198
D L +R L + +NR+ T+ PG F L +LS + L NPF+C C L WL W
Sbjct: 621 SNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRK 680
Query: 199 TRVSLPEPDSIACASPPALQGVPV 222
R+ P C P L+ +P+
Sbjct: 681 RRIVSGNP---RCQKPFFLKEIPI 701
Score = 105 bits (262), Expect = 2e-22
Identities = 64/195 (32%), Positives = 91/195 (46%), Gaps = 32/195 (16%)
Query: 20 CPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRGAFADVTQVTS 79
CPE C C++ C+ K LR +P G+P +VT L L N +T +
Sbjct: 725 CPEQCTCMETVVR----CSNKGLRALPRGMPKDVTELYLEGNHLTAV------------- 767
Query: 80 LWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLP 139
P L+ L L +DLS+N IS N+S L L +++NRL +P
Sbjct: 768 ------------PRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIP 815
Query: 140 RDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAAST 199
A L LR L ++ N + ++ G+F+ L++LSHL L NP HC C L WL W
Sbjct: 816 VHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEW---V 872
Query: 200 RVSLPEPDSIACASP 214
+ EP C+SP
Sbjct: 873 KAGYKEPGIARCSSP 887
Score = 104 bits (259), Expect = 3e-22
Identities = 61/199 (30%), Positives = 94/199 (47%), Gaps = 7/199 (3%)
Query: 19 SCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRGAFADVTQVT 78
SCP PC C ++ DC K L E+P LP + + L N I + GAF ++
Sbjct: 279 SCPSPCTC----SNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLK 334
Query: 79 SLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSL 138
+ ++ N++ + P A L L +L L N I+ L +LQLL +N N++ L
Sbjct: 335 RIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCL 394
Query: 139 PRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAAS 198
+ L +L L + +N+L+T++ G F L ++ L L NPF C C L WL +
Sbjct: 395 RVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQD 454
Query: 199 TRVSLPEPDSIACASPPAL 217
+ E C+SP L
Sbjct: 455 NPI---ETSGARCSSPRRL 470
Score = 99.4 bits (246), Expect = 1e-20
Identities = 72/254 (28%), Positives = 107/254 (42%), Gaps = 38/254 (14%)
Query: 17 AGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRGAFADVTQ 76
A +CP C C + DC LR VP G+P N L L N IT + + FA +
Sbjct: 31 AVACPTKCTC----SAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKN 86
Query: 77 VTSLWLAHNEVRTVEPGALAVLSQLKNL------------------------DLSHNFIS 112
+ L L N+V +E GA L QL+ L DLS N I
Sbjct: 87 LRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQ 146
Query: 113 SFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSA 172
P R ++ ++ L++++N + + A AL DL L +NNN + + +F+ +
Sbjct: 147 GIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPK 206
Query: 173 LSHLQLYHNPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPV-------YRL 225
+ L+L+ N +C C L WL W R C +P L+G V Y
Sbjct: 207 IRTLRLHSNHLYCDCHLAWLSDWLRQRRT---VGQFTLCMAPVHLRGFNVADVQKKEYVC 263
Query: 226 PALPCAPPSVHLSA 239
PA PPS + ++
Sbjct: 264 PAPHSEPPSCNANS 277
>gi|193083136 leucine-rich repeat, immunoglobulin-like and
transmembrane domains 3 [Homo sapiens]
Length = 634
Score = 114 bits (284), Expect = 4e-25
Identities = 95/390 (24%), Positives = 157/390 (40%), Gaps = 71/390 (18%)
Query: 41 ELREVPEGLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQ 100
++ E+P LP + L + I + AF + ++ LW+ +N V +++P + L Q
Sbjct: 2 DMNELPTNLPVDTVKLRIEKTVIRRISAEAFYYLVELQYLWVTYNSVASIDPSSFYNLKQ 61
Query: 101 LKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLR 160
L L L N +++FPW+ L ++ L+ L +++N++ S+P +AL L +L L +++NRL
Sbjct: 62 LHELRLDGNSLAAFPWASLLDMPLLRTLDLHNNKITSVPNEALRYLKNLAYLDLSSNRLT 121
Query: 161 TLAP--------------GTFDALSALSHLQLYHNPFHCGCGLVWL--QAWAASTRVSLP 204
TL P G D + L L NP+ C C + + + + L
Sbjct: 122 TLPPDFLESWTHLVSTPSGVLDLSPSRIILGLQDNPWFCDCHISKMIELSKVVDPAIVLL 181
Query: 205 EPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAEPPLEAPGTPLRAGLAFVLHCIADG 264
+P + C+ P L G+ R C PSV SA + A G+ + +L C A G
Sbjct: 182 DP-LMTCSEPERLTGILFQRAELEHCLKPSVMTSATKIMSALGSNV------LLRCDATG 234
Query: 265 HPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEGEGEGDGDLLTQTQAQ-TPTPAPAW 323
PTP++ W D + T Q +P W
Sbjct: 235 FPTPQITWT-----------------------------RSDSSPVNYTVIQESPEEGVRW 265
Query: 324 PAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNELGANSTSIRVAVAATG----PPK 379
T +S+K+AG Y C+A N G + + V V PP
Sbjct: 266 SIMSLTG--------------ISSKDAGDYKCKAKNLAGMSEAVVTVTVLGITTTPIPPD 311
Query: 380 HAPGAGGEPDGQAPTSERKSTAKGRGNSVL 409
+ G P+ +ST+ +S L
Sbjct: 312 TSERTGDHPEWDVQPGSGRSTSVSSASSYL 341
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 110 bits (274), Expect = 6e-24
Identities = 78/273 (28%), Positives = 123/273 (45%), Gaps = 18/273 (6%)
Query: 7 LWLVWALLGVAGS-----CPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSAN 61
L+ W L V CP C C C + L VP P + L L N
Sbjct: 18 LFCAWGTLAVVAQKPGAGCPSRCLCFRTTVR----CMHLLLEAVPAVAP-QTSILDLRFN 72
Query: 62 KITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRN 121
+I ++ GAF + + +L L +N+++ + GA L LK L L N I S +
Sbjct: 73 RIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKG 132
Query: 122 LSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHN 181
L++L+ L ++ N++ +L D+ LP L L ++NNR+ L PGTF+ L ++ L+L N
Sbjct: 133 LASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSN 192
Query: 182 PFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRL--PALPCAPPSVHLSA 239
HC C ++WL + S + C P +QG V + L C P +++
Sbjct: 193 TLHCDCEILWLADLLKTYAESGNAQAAAICEYPRRIQGRSVATITPEELNCERP--RITS 250
Query: 240 EPPLEAPGTPLRAGLAFVLHCIADGHPTPRLQW 272
EP + +G C A+G+P P + W
Sbjct: 251 EP----QDADVTSGNTVYFTCRAEGNPKPEIIW 279
Score = 30.4 bits (67), Expect = 6.2
Identities = 11/30 (36%), Positives = 16/30 (53%)
Query: 243 LEAPGTPLRAGLAFVLHCIADGHPTPRLQW 272
++ T + G + L C A GHP PR+ W
Sbjct: 346 IQPQNTEVLVGESVTLECSATGHPPPRISW 375
>gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens]
Length = 713
Score = 107 bits (268), Expect = 3e-23
Identities = 99/339 (29%), Positives = 144/339 (42%), Gaps = 57/339 (16%)
Query: 42 LREVP----EGLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAV 97
LRE+ EGL + + +LS N++ + R A V + L L N ++ V PG A
Sbjct: 225 LREISDYALEGLQS-LESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFAN 283
Query: 98 LSQLKNLDLSHN----FISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLR 153
+ LK L L++ I F +L L+ L + N+ RL + A LP + +L
Sbjct: 284 MLHLKELGLNNMEELVSIDKFALVNLPELTKLDIT--NNPRLSFIHPRAFHHLPQMETLM 341
Query: 154 INNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAASTRVSLPEPDSIACAS 213
+NNN L L T ++L L + L+ NP C C + W A A TRV EP S CA
Sbjct: 342 LNNNALSALHQQTVESLPNLQEVGLHGNPIRCDCVIRW--ANATGTRVRFIEPQSTLCAE 399
Query: 214 PPALQGVPVYRLPALPCAPPSVHLSAEPPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQ 273
PP LQ +PV +P + L P P + +G + VLHC A P P + W
Sbjct: 400 PPDLQRLPVREVPFREMTDHCLPL-ISPRSFPPSLQVASGESMVLHCRALAEPEPEIYW- 457
Query: 274 LQIPGGTVVLEPPVLSGEDDGVGAEEGEGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFL 333
TP PA A R+
Sbjct: 458 -----------------------------------------VTPAGLRLTPA-HAGRRYR 475
Query: 334 ALANGSLLVPLLSAKEAGVYTCRAHNELGANSTSIRVAV 372
G+L + ++A+EAG+YTC A N +GA++ ++ V V
Sbjct: 476 VYPEGTLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVV 514
Score = 66.2 bits (160), Expect = 1e-10
Identities = 55/193 (28%), Positives = 80/193 (41%), Gaps = 14/193 (7%)
Query: 3 PLRALWLVWALLGVAG-----SCPEPCAC------VDKYAHQFA---DCAYKELREVPEG 48
PL W+ A V CP CAC + +++ A DC L VP
Sbjct: 7 PLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAVPPA 66
Query: 49 LPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSH 108
LPA TL L +N I + + + +T L L+ N L QL +L L
Sbjct: 67 LPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEE 126
Query: 109 NFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFD 168
N ++ L++LQ L +NHN+L + A L +L L +N+N LR + F+
Sbjct: 127 NQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFE 186
Query: 169 ALSALSHLQLYHN 181
L L L + N
Sbjct: 187 MLPNLEILMIGGN 199
Score = 57.0 bits (136), Expect = 6e-08
Identities = 40/155 (25%), Positives = 73/155 (47%), Gaps = 5/155 (3%)
Query: 27 VDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNE 86
+D + F+D + +P+ L +L L N++T L +FA + + L+L HN+
Sbjct: 98 LDLSQNSFSDARDCDFHALPQLL-----SLHLEENQLTRLEDHSFAGLASLQELYLNHNQ 152
Query: 87 VRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGAL 146
+ + P A + LS L L L+ N + + L L++L + N++ ++ L
Sbjct: 153 LYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPL 212
Query: 147 PDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHN 181
+LRSL + LR ++ + L +L L Y N
Sbjct: 213 ANLRSLVLAGMNLREISDYALEGLQSLESLSFYDN 247
Score = 32.7 bits (73), Expect = 1.3
Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 12/86 (13%)
Query: 537 GGAAVQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQV--VFSTKKEL------- 587
G A +R+ G ++Y L T Y CL +A H Q+ V++ KE
Sbjct: 566 GQGATALARLPRGTHSYNITRLLQATEYWACLQVAFADAHTQLACVWARTKEATSCHRAL 625
Query: 588 ---PSLLVIVAVSVFLLVLATVPLLG 610
P L+ I+A++V LL LG
Sbjct: 626 GDRPGLIAILALAVLLLAAGLAAHLG 651
>gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens]
Length = 713
Score = 107 bits (268), Expect = 3e-23
Identities = 99/339 (29%), Positives = 144/339 (42%), Gaps = 57/339 (16%)
Query: 42 LREVP----EGLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAV 97
LRE+ EGL + + +LS N++ + R A V + L L N ++ V PG A
Sbjct: 225 LREISDYALEGLQS-LESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFAN 283
Query: 98 LSQLKNLDLSHN----FISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLR 153
+ LK L L++ I F +L L+ L + N+ RL + A LP + +L
Sbjct: 284 MLHLKELGLNNMEELVSIDKFALVNLPELTKLDIT--NNPRLSFIHPRAFHHLPQMETLM 341
Query: 154 INNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAASTRVSLPEPDSIACAS 213
+NNN L L T ++L L + L+ NP C C + W A A TRV EP S CA
Sbjct: 342 LNNNALSALHQQTVESLPNLQEVGLHGNPIRCDCVIRW--ANATGTRVRFIEPQSTLCAE 399
Query: 214 PPALQGVPVYRLPALPCAPPSVHLSAEPPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQ 273
PP LQ +PV +P + L P P + +G + VLHC A P P + W
Sbjct: 400 PPDLQRLPVREVPFREMTDHCLPL-ISPRSFPPSLQVASGESMVLHCRALAEPEPEIYW- 457
Query: 274 LQIPGGTVVLEPPVLSGEDDGVGAEEGEGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFL 333
TP PA A R+
Sbjct: 458 -----------------------------------------VTPAGLRLTPA-HAGRRYR 475
Query: 334 ALANGSLLVPLLSAKEAGVYTCRAHNELGANSTSIRVAV 372
G+L + ++A+EAG+YTC A N +GA++ ++ V V
Sbjct: 476 VYPEGTLELRRVTAEEAGLYTCVAQNLVGADTKTVSVVV 514
Score = 66.2 bits (160), Expect = 1e-10
Identities = 55/193 (28%), Positives = 80/193 (41%), Gaps = 14/193 (7%)
Query: 3 PLRALWLVWALLGVAG-----SCPEPCAC------VDKYAHQFA---DCAYKELREVPEG 48
PL W+ A V CP CAC + +++ A DC L VP
Sbjct: 7 PLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAVPPA 66
Query: 49 LPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSH 108
LPA TL L +N I + + + +T L L+ N L QL +L L
Sbjct: 67 LPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEE 126
Query: 109 NFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFD 168
N ++ L++LQ L +NHN+L + A L +L L +N+N LR + F+
Sbjct: 127 NQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFE 186
Query: 169 ALSALSHLQLYHN 181
L L L + N
Sbjct: 187 MLPNLEILMIGGN 199
Score = 57.0 bits (136), Expect = 6e-08
Identities = 40/155 (25%), Positives = 73/155 (47%), Gaps = 5/155 (3%)
Query: 27 VDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNE 86
+D + F+D + +P+ L +L L N++T L +FA + + L+L HN+
Sbjct: 98 LDLSQNSFSDARDCDFHALPQLL-----SLHLEENQLTRLEDHSFAGLASLQELYLNHNQ 152
Query: 87 VRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGAL 146
+ + P A + LS L L L+ N + + L L++L + N++ ++ L
Sbjct: 153 LYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPL 212
Query: 147 PDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHN 181
+LRSL + LR ++ + L +L L Y N
Sbjct: 213 ANLRSLVLAGMNLREISDYALEGLQSLESLSFYDN 247
Score = 32.7 bits (73), Expect = 1.3
Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 12/86 (13%)
Query: 537 GGAAVQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQV--VFSTKKEL------- 587
G A +R+ G ++Y L T Y CL +A H Q+ V++ KE
Sbjct: 566 GQGATALARLPRGTHSYNITRLLQATEYWACLQVAFADAHTQLACVWARTKEATSCHRAL 625
Query: 588 ---PSLLVIVAVSVFLLVLATVPLLG 610
P L+ I+A++V LL LG
Sbjct: 626 GDRPGLIAILALAVLLLAAGLAAHLG 651
>gi|139948432 adlican [Homo sapiens]
Length = 2828
Score = 107 bits (266), Expect = 5e-23
Identities = 80/282 (28%), Positives = 115/282 (40%), Gaps = 52/282 (18%)
Query: 3 PLRALW--------LVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVT 54
P RA W L+W VA +CP PCAC Y C ++ L VP G+ +V
Sbjct: 2 PKRAHWGALSVVLILLWGHPRVALACPHPCAC---YVPSEVHCTFRSLASVPAGIAKHVE 58
Query: 55 TLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSF 114
++L N I L +FA +T++ L + NE+ ++ GAL LS L+ S+N +
Sbjct: 59 RINLGFNSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRDLSSLQVFKFSYNKLRVI 118
Query: 115 PWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDA----- 169
L+ LS L L ++HN++ + A L LR L + N L L P TF
Sbjct: 119 TGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGNLLHQLHPSTFSTFTFLD 178
Query: 170 ---LSALSHLQLYH------------------------NPFHCGCGLVWLQAWAASTRVS 202
LS + HL L NP+ C C + W W A +R
Sbjct: 179 YFRLSTIRHLYLAENMVRTLPASMLRNMPLLENLYLQGNPWTCDCEMRWFLEWDAKSRGI 238
Query: 203 LPEPDSIA---------CASPPALQGVPVYRLPALPCAPPSV 235
L A C SP L +++L + C PS+
Sbjct: 239 LKCKKDKAYEGGQLCAMCFSPKKLYKHEIHKLKDMTCLKPSI 280
Score = 41.2 bits (95), Expect = 0.004
Identities = 45/193 (23%), Positives = 74/193 (38%), Gaps = 33/193 (17%)
Query: 281 VVLEPPVLSGEDDGVGAEEGEGEGDGDLLTQTQAQTPTPAPAWPAPPA--------TPRF 332
+V P E D V G+ G+ L P +W P T
Sbjct: 571 LVQSPSTQPAEKDTVTI--GKNPGESVTLPCNALAIPEAHLSWILPNRRIINDLANTSHV 628
Query: 333 LALANGSLLVPLLSAKEAGVYTCRAHNELGANSTSIRVAVAATG---PPKHA--PGAGG- 386
L NG+L +P + ++G Y C A N+ GA+ ++ + V G P K PGA
Sbjct: 629 YMLPNGTLSIPKVQVSDSGYYRCVAVNQQGADHFTVGITVTKKGSGLPSKRGRRPGAKAL 688
Query: 387 --------EPDGQAPTSERKSTAK----GRGNSVLPSKPEGKIKG-----QGLAKVSILG 429
E +G + + ++T++ + V + I G +G K+ +
Sbjct: 689 SRVREDIVEDEGGSGMGDEENTSRRLLHPKDQEVFLKTKDDAINGDKKAKKGRRKLKLWK 748
Query: 430 ETETEPEEDTSEG 442
+E EPE + +EG
Sbjct: 749 HSEKEPETNVAEG 761
Score = 39.7 bits (91), Expect = 0.010
Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 9/74 (12%)
Query: 316 TPTPAPAWPAP---------PATPRFLALANGSLLVPLLSAKEAGVYTCRAHNELGANST 366
TP P +W P P R N +L + S + GVY C A N GA+S
Sbjct: 1977 TPAPQISWIFPDRRVWQTVSPVEGRITLHENRTLSIKEASFSDRGVYKCVASNAAGADSL 2036
Query: 367 SIRVAVAATGPPKH 380
+IR+ VAA P H
Sbjct: 2037 AIRLHVAALPPVIH 2050
Score = 38.1 bits (87), Expect = 0.030
Identities = 28/113 (24%), Positives = 43/113 (38%), Gaps = 36/113 (31%)
Query: 260 CIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEGEGEGDGDLLTQTQAQTPTP 319
C+A G P P + W L P G++V + +D G
Sbjct: 2265 CVATGLPNPEISWSL--PDGSLVNS--FMQSDDSG------------------------- 2295
Query: 320 APAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNELGANSTSIRVAV 372
T R++ NG+L + +E G YTC A N++G + +RV V
Sbjct: 2296 -------GRTKRYVVFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMRVRVKV 2341
Score = 37.0 bits (84), Expect = 0.067
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 8/72 (11%)
Query: 309 LTQTQAQTPTPAPAWPAPPATP--------RFLALANGSLLVPLLSAKEAGVYTCRAHNE 360
L + A TPTP+ W P T RF A+G L + LS+ +AG Y C A N
Sbjct: 2562 LNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVDAGAYRCVARNA 2621
Query: 361 LGANSTSIRVAV 372
G + + V
Sbjct: 2622 AGHTERLVSLKV 2633
Score = 36.2 bits (82), Expect = 0.11
Identities = 46/199 (23%), Positives = 68/199 (34%), Gaps = 61/199 (30%)
Query: 235 VHLSAEPPL----EAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQ--------------- 275
+H++A PP+ + L GL+ +HC A P P ++W L
Sbjct: 2040 LHVAALPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNL 2099
Query: 276 --IPGGTVVLE--PPVLSGEDDGVGAE-EGEGEGDGDLLTQTQAQT-------------- 316
P GT+ + P SG + V A G L Q A
Sbjct: 2100 FVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRTVQLNVQRAAANARITGTSPRRTDVR 2159
Query: 317 --------------PTPAPAWPAPPAT---------PRFLALANGSLLVPLLSAKEAGVY 353
P P W P R ANG+L+V ++ K+AG Y
Sbjct: 2160 YGGTLKLDCSASGDPWPRILWRLPSKRMIDALFSFDSRIKVFANGTLVVKSVTDKDAGDY 2219
Query: 354 TCRAHNELGANSTSIRVAV 372
C A N++G + ++V V
Sbjct: 2220 LCVARNKVGDDYVVLKVDV 2238
Score = 35.4 bits (80), Expect = 0.19
Identities = 21/52 (40%), Positives = 24/52 (46%)
Query: 326 PPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNELGANSTSIRVAVAATGP 377
P R L NG+L V S + G Y CR E G + TSI V V A P
Sbjct: 2682 PQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPVIVIAYPP 2733
Score = 34.7 bits (78), Expect = 0.33
Identities = 25/105 (23%), Positives = 44/105 (41%), Gaps = 14/105 (13%)
Query: 317 PTPAPAWPAPP------ATPRFLALANGSLLVPLLSAKEAGVYTCRAHNELGANSTSIRV 370
P P W +P ++ ++ +G+LL+ ++G YTC N G + ++ +
Sbjct: 2374 PMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQRSDSGNYTCLVRNSAGEDRKTVWI 2433
Query: 371 AVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEG 415
V PPK G P+ P + + A G ++ K EG
Sbjct: 2434 HVNVQ-PPK----INGNPN---PITTVREIAAGGSRKLIDCKAEG 2470
Score = 31.6 bits (70), Expect = 2.8
Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 9/101 (8%)
Query: 281 VVLEPPVLSGEDDGVGAEEGEGEGDGDLLTQTQAQ-TPTPAPAW--------PAPPATPR 331
V ++PP ++G + + G L +A+ PTP W PAP R
Sbjct: 2435 VNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNR 2494
Query: 332 FLALANGSLLVPLLSAKEAGVYTCRAHNELGANSTSIRVAV 372
NGSL + L ++ C A NE G +++ V
Sbjct: 2495 ITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLILQLTV 2535
>gi|14149694 retina specific protein PAL [Homo sapiens]
Length = 623
Score = 105 bits (262), Expect = 2e-22
Identities = 155/655 (23%), Positives = 244/655 (37%), Gaps = 145/655 (22%)
Query: 6 ALWLVWALLGVA------GSCPEPCACV-----DKYAHQFADCAYKELREVPEGLPANVT 54
AL ++W LL +A G CP C+C D + C ++ P +P + +
Sbjct: 4 ALGMLW-LLALAWPPQARGFCPSQCSCSLHIMGDGSKARTVVCNDPDMTLPPASIPPDTS 62
Query: 55 TLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSF 114
L L I + AF + ++ LWL +N + + L L +L+ L L N +++F
Sbjct: 63 RLRLERTAIRRVPGEAFRPLGRLEQLWLPYNALSELNALMLRGLRRLRELRLPGNRLAAF 122
Query: 115 PWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALS 174
PW+ LR+ L+LL + NRL ++P +A L +L L +++N+L L + + + +
Sbjct: 123 PWAALRDAPKLRLLDLQANRLSAVPAEAARFLENLTFLDLSSNQLMRLPQ---ELIVSWA 179
Query: 175 HLQ---------------LYHNPFHCGCGLV----WLQAWAASTRVSLPEPDSIACASPP 215
HL+ L NP+ C C L L WA + E + CASP
Sbjct: 180 HLETGIFPPGHHPRRVLGLQDNPWACDCRLYDLVHLLDGWAPNLAFIETE---LRCASPR 236
Query: 216 ALQGVPVYRLPALPCAPPSVHLSAEPPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQ 275
+L GV +L C P +H P A L G A +L C A G P P + W+
Sbjct: 237 SLAGVAFSQLELRKCQGPELH-----PGVASIRSLLGGTA-LLRCGATGVPGPEMSWR-- 288
Query: 276 IPGGTVVLEPPVLSGEDDGVGAEEGEGEGDGDLLTQT-QAQTPTPAPAWPAPPATPRFLA 334
+G L T + + +W
Sbjct: 289 ---------------------------RANGRPLNGTVHQEVSSDGTSWTL--------- 312
Query: 335 LANGSLLVPLLSAKEAGVYTCRAHNELGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPT 394
L +P +S ++G Y C+A N LGA+ T I + V T PP +G A T
Sbjct: 313 -----LGLPAVSHLDSGDYICQAKNFLGASETVISLIV--TEPPTSTEHSGSPGALWART 365
Query: 395 SERKSTAKGRGNSVLPSKPEGKIKGQGLAKVSILGETETEPEEDTSEGEEAEDQILADPA 454
A V P+ + K ++L T P +++ E + D
Sbjct: 366 GGGGEAAAYNNKLVARHVPQ-------IPKPAVLA---TGPSVPSTKEELTLEHFQMDAL 415
Query: 455 EEQRCGNGDPSRYVSNHAFNQSAELKPHVFELGVIALDVAEREARVQLTPLAARWGPGPG 514
E G PS A + V +G D + V P A
Sbjct: 416 GELSDGRAGPS----------EARMVRSVKVVG----DTYHSVSLVWKAPQA-------- 453
Query: 515 GAGGAPRPGRRPLRLLYLCPAGGGAAVQWSRVEEGVNAYWFRGLRPGTNYSVCLALAG-- 572
+ L G +++ V+ G GL P T Y C+ + G
Sbjct: 454 ---------KNTTAFSVLYAVFGQHSMRRVIVQPGKTRVTITGLLPKTKYVACVCVQGLV 504
Query: 573 ---EACHVQVVFSTKKELPS-----LLVIVAVSVFLLVLATVPLLGAACCHLLAK 619
E C V+FST + + + L+ +V +SV +++ +PL CC L K
Sbjct: 505 PRKEQC---VIFSTNEVVDAENTQQLINVVVISVAIVI--ALPLTLLVCCSALQK 554
>gi|10190722 leucine-rich repeats and transmembrane domains 1 [Homo
sapiens]
Length = 345
Score = 104 bits (260), Expect = 3e-22
Identities = 82/271 (30%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 10 VWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRG 69
V LL V SCP+ C C + + F DC+ + L E+P LP TL L N+I L
Sbjct: 11 VIVLLQVVCSCPDKCYC--QSSTNFVDCSQQGLAEIPSHLPPQTRTLHLQDNQIHHLPAF 68
Query: 70 AFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLK 129
AF V + +L L++N + + PGA L L+ L+L+ N + S +L L+ L
Sbjct: 69 AFRSVPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLTQNSLLSLESRLFHSLPQLRELD 128
Query: 130 MNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGL 189
++ N + LP +L L + N+L+ L +++ ++ L L N + C C L
Sbjct: 129 LSSNNISHLPTSLGETWENLTILAVQQNQLQQLDRALLESMPSVRLLLLKDNLWKCNCHL 188
Query: 190 VWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLP---ALPC---APPSVHLSAEPPL 243
+ L+ W D I C SP +G + R+P PC AP V A+ P
Sbjct: 189 LGLKLWLEKFVYKGGLTDGIICESPDTWKGKDLLRIPHELYQPCPLPAPDPVSSQAQWPG 248
Query: 244 EAPGTPLR------AGLAFVLHCIADGHPTP 268
A G LR AG +L C P P
Sbjct: 249 SAHGVVLRPPENHNAGERELLECELKPKPRP 279
>gi|31542244 leucine rich repeat and fibronectin type III domain
containing 5 [Homo sapiens]
Length = 719
Score = 99.4 bits (246), Expect = 1e-20
Identities = 109/471 (23%), Positives = 171/471 (36%), Gaps = 130/471 (27%)
Query: 13 LLGVAGS---CPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRG 69
L+G+A CP+ C C + CA K L VP + L L+ N +T ++R
Sbjct: 10 LIGIAVKAQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRK 69
Query: 70 AFADVTQVTSLWLAHNEVRTVEPGALAVLSQLK--------------------------- 102
FA++T + L L+ N + + P A A L L+
Sbjct: 70 DFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLI 129
Query: 103 ---------------------NLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRD 141
LDLS+N + + PW + + +L L ++HN + ++P+
Sbjct: 130 LNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKG 189
Query: 142 ALGALPDLRSLRINNNRLRTLAPG-TFDALSALS----------HLQLYHNPFHCGCGLV 190
L + L + +N+L+ L P F L+ L NP HC C L+
Sbjct: 190 TFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELL 249
Query: 191 WLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLP--ALPCAPPSV--HLSAEPPLEAP 246
WL+ R+S E D CASPP L G + +P C PP + H LE
Sbjct: 250 WLR------RLS-REDDLETCASPPLLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLE-- 300
Query: 247 GTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEGEGEGDG 306
G L C A G P P + W + P +G
Sbjct: 301 ------GQRATLRCKARGDPEPAIHW----------ISP-------------------EG 325
Query: 307 DLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNELGANST 366
L++ R L NG+L + + + K+ G +TC A N G +
Sbjct: 326 KLISN-----------------ATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQ 368
Query: 367 SIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKI 417
+ + + ++ EPD P S ST+ G++ S + K+
Sbjct: 369 IVDLHIIKLPHLLNSTNHIHEPD---PGSSDISTSTKSGSNTSSSNGDTKL 416
>gi|51317373 netrin-G1 ligand [Homo sapiens]
Length = 640
Score = 97.8 bits (242), Expect = 3e-20
Identities = 61/182 (33%), Positives = 97/182 (53%), Gaps = 8/182 (4%)
Query: 3 PLRALWLVWALLGVAG-----SCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLS 57
PL + L LL VAG +CP C+C ++++ C K LREVP+G+ N L+
Sbjct: 25 PLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKVI--CVRKNLREVPDGISTNTRLLN 82
Query: 58 LSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWS 117
L N+I +++ +F + + L L+ N +RT+E GA L+ L L+L N +++ P
Sbjct: 83 LHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNG 142
Query: 118 DLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINN-NRLRTLAPGTFDALSALSHL 176
LS L+ L + +N + S+P A +P LR L + RL ++ G F+ LS L +L
Sbjct: 143 AFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYL 202
Query: 177 QL 178
L
Sbjct: 203 NL 204
Score = 62.0 bits (149), Expect = 2e-09
Identities = 75/354 (21%), Positives = 127/354 (35%), Gaps = 112/354 (31%)
Query: 33 QFADCAYKELREVPEGLPA-NVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVE 91
++ + A LRE+P P + L LS N ++ +R G+F + + LW+ ++++ +E
Sbjct: 200 RYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIE 259
Query: 92 PGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRS 151
A L L ++L+HN ++ P L L+ + ++HN
Sbjct: 260 RNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN------------------ 301
Query: 152 LRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAASTRVSLPEPDSIAC 211
P++C C ++WL W + P + AC
Sbjct: 302 ------------------------------PWNCNCDILWLSWW-----IKDMAPSNTAC 326
Query: 212 A----SPPALQGVPVYRLPA--LPCAPPSVHLSAEPPLEAPGTPLRAGLAFVLHCIADGH 265
+PP L+G + L C P + EPP + T G+A L C A
Sbjct: 327 CARCNTPPNLKGRYIGELDQNYFTCYAPVI---VEPPADLNVT---EGMAAELKCRASTS 380
Query: 266 PTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEGEGEGDGDLLTQTQAQTPTPAPAWPA 325
T + W P GTV+ GA +
Sbjct: 381 LT-SVSW--ITPNGTVMTH-----------GAYK-------------------------- 400
Query: 326 PPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNELG--ANSTSIRVAVAATGP 377
R L++G+L ++ ++ G+YTC N +G S ++ V A T P
Sbjct: 401 ----VRIAVLSDGTLNFTNVTVQDTGMYTCMVSNSVGNTTASATLNVTAATTTP 450
>gi|194440719 chondroadherin-like [Homo sapiens]
Length = 762
Score = 95.1 bits (235), Expect = 2e-19
Identities = 74/222 (33%), Positives = 94/222 (42%), Gaps = 36/222 (16%)
Query: 7 LWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVL 66
L L A A CP+ C C + H C Y+ L EVP+ +P L L N + V+
Sbjct: 20 LLLAPARQAAAQRCPQACICDNSRRH--VACRYQNLTEVPDAIPELTQRLDLQGNLLKVI 77
Query: 67 RRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQ 126
AF V +T L L H EV V GA R L L
Sbjct: 78 PAAAFQGVPHLTHLDLRHCEVELVAEGA------------------------FRGLGRLL 113
Query: 127 LLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCG 186
LL + N L LP++AL L LR L + N L L PGTF AL AL+ L L HN
Sbjct: 114 LLNLASNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHN----- 168
Query: 187 CGLVWLQAWA----ASTRVSLPEPDSIACASPPALQGVPVYR 224
LV+L A A R ++++ +P AL G+P R
Sbjct: 169 -ALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALR 209
Score = 83.2 bits (204), Expect = 8e-16
Identities = 56/162 (34%), Positives = 76/162 (46%), Gaps = 2/162 (1%)
Query: 20 CPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRGAFADVTQVTS 79
CP C CV + H + C L+ VP G P++ L L N + R AF + + S
Sbjct: 396 CPRACVCVPESRH--SSCEGCGLQAVPRGFPSDTQLLDLRRNHFPSVPRAAFPGLGHLVS 453
Query: 80 LWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLP 139
L L H + +E GALA L +L L LS N ++ + L L L + NR +P
Sbjct: 454 LHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNRFLQVP 513
Query: 140 RDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHN 181
AL ALP L SL + +N + LAPG AL + L N
Sbjct: 514 GAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGN 555
Score = 76.3 bits (186), Expect = 1e-13
Identities = 64/204 (31%), Positives = 85/204 (41%), Gaps = 26/204 (12%)
Query: 38 AYKELREVPEGLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAV 97
A +ELR G + TL+L+ N + L AF + +V L L+HN + + P ALA
Sbjct: 145 ALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAG 204
Query: 98 LSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNN 157
L L+ L L HN + + P L L L++ HN L + ALP LR L ++
Sbjct: 205 LPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGG 264
Query: 158 RLRTLAPGTF----------------DAL------SALSHLQLYHNPFHCGCGLVWLQAW 195
L+ L P F D L L L+L NP CGC L W
Sbjct: 265 ALQALGPRAFAHCPRLHTLDLRGNQLDTLPPLQGPGQLRRLRLQGNPLWCGCQARPLLEW 324
Query: 196 AASTRVSLPEPDSIACASPPALQG 219
A RV AC P L+G
Sbjct: 325 LARARVR----SDGACQGPRRLRG 344
Score = 72.4 bits (176), Expect = 1e-12
Identities = 54/164 (32%), Positives = 78/164 (47%), Gaps = 8/164 (4%)
Query: 58 LSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWS 117
LS N+IT + GA ++ L L N++R V GAL L L L LS N + +
Sbjct: 552 LSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDG 611
Query: 118 DLRNLS-ALQLLKMNHNRLGSLPRDALGAL-PDLRSLRINNNRLRTLAPGTFDALSALSH 175
+ + +LQ L +N + L + A L P L+SL + N+LR L +LS L
Sbjct: 612 AFQPVGRSLQHLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALP--ALPSLSQLEL 669
Query: 176 LQLYHNPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQG 219
+ L NPFHC C L+ L W + + CA+PP +G
Sbjct: 670 IDLSSNPFHCDCQLLPLHRWLTGLNLRV----GATCATPPNARG 709
>gi|84781739 leucine-rich repeats and transmembrane domains 2 [Homo
sapiens]
Length = 370
Score = 94.7 bits (234), Expect = 3e-19
Identities = 66/219 (30%), Positives = 101/219 (46%), Gaps = 2/219 (0%)
Query: 8 WLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLR 67
W+ + +CP C C + DC+ L VP +PA TL L NK++ L
Sbjct: 27 WIALYAVEALPTCPFSCKCDSRSLE--VDCSGLGLTTVPPDVPAATRTLLLLNNKLSALP 84
Query: 68 RGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQL 127
AFA+++ + L L++N + + L+ L L L +N I + LR+ L+
Sbjct: 85 SWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTLDRDLLRHSPLLRH 144
Query: 128 LKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGC 187
L ++ N L LP L LRSL + +NRL+ L TF+ L+ L LQ+ NP+ C C
Sbjct: 145 LDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLANLQLLQVGDNPWECDC 204
Query: 188 GLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLP 226
L + W D +AC P L+G + +P
Sbjct: 205 NLREFKHWMEWFSYRGGRLDQLACTLPKELRGKDMRMVP 243
>gi|113423021 PREDICTED: similar to hCG1820409 [Homo sapiens]
Length = 578
Score = 93.2 bits (230), Expect = 8e-19
Identities = 90/302 (29%), Positives = 117/302 (38%), Gaps = 50/302 (16%)
Query: 4 LRALWLVWALLGV-AGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANK 62
L+ L LV A L A CP C C + ELR+ P +P + L++
Sbjct: 206 LQGLLLVAAALSQPAAPCPFQCYCFGGPKLLLRCASGAELRQPPRDVPPDARNLTIVGAN 265
Query: 63 ITVLRRGAFAD------------VTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNF 110
+TVLR AFA + +++L L HN + VE GA L L LDLSHN
Sbjct: 266 LTVLRAAAFAGGDGDGDQAAGVRLPLLSALRLTHNHIEVVEDGAFDGLPSLAALDLSHNP 325
Query: 111 ISSFPWSDLRNLSALQLLKMNHNRLGSLPR------DALGALPDLRSLRINNNRLRTLAP 164
+ + R L AL+ L++NH + P AL L +LR L + N L L P
Sbjct: 326 LRALGGGAFRGLPALRSLQLNHALVRGGPALLAALDAALAPLAELRLLGLAGNALSRLPP 385
Query: 165 GTF--------------------DALSALS--------HLQLYHNPFHCGCGLVWLQAWA 196
D L AL L L NP CGC L AW
Sbjct: 386 AALRLARLEQLDVRLNALAGLDPDELRALERDGGLPGPRLLLADNPLRCGCAARPLLAWL 445
Query: 197 ASTRVSLPEPDSIACASPPALQGVPVYRLPA--LPCAPPSVHLSAEPPLEAPGTPLRAGL 254
+ +P+ + CA+P AL P+ L L CA E EA G L A
Sbjct: 446 RNATERVPDSRRLRCAAPRALLDRPLLDLDGARLRCADSGADARGE-EAEAAGPELEASY 504
Query: 255 AF 256
F
Sbjct: 505 VF 506
>gi|113422497 PREDICTED: similar to hCG1820409 [Homo sapiens]
Length = 578
Score = 93.2 bits (230), Expect = 8e-19
Identities = 90/302 (29%), Positives = 117/302 (38%), Gaps = 50/302 (16%)
Query: 4 LRALWLVWALLGV-AGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANK 62
L+ L LV A L A CP C C + ELR+ P +P + L++
Sbjct: 206 LQGLLLVAAALSQPAAPCPFQCYCFGGPKLLLRCASGAELRQPPRDVPPDARNLTIVGAN 265
Query: 63 ITVLRRGAFAD------------VTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNF 110
+TVLR AFA + +++L L HN + VE GA L L LDLSHN
Sbjct: 266 LTVLRAAAFAGGDGDGDQAAGVRLPLLSALRLTHNHIEVVEDGAFDGLPSLAALDLSHNP 325
Query: 111 ISSFPWSDLRNLSALQLLKMNHNRLGSLPR------DALGALPDLRSLRINNNRLRTLAP 164
+ + R L AL+ L++NH + P AL L +LR L + N L L P
Sbjct: 326 LRALGGGAFRGLPALRSLQLNHALVRGGPALLAALDAALAPLAELRLLGLAGNALSRLPP 385
Query: 165 GTF--------------------DALSALS--------HLQLYHNPFHCGCGLVWLQAWA 196
D L AL L L NP CGC L AW
Sbjct: 386 AALRLARLEQLDVRLNALAGLDPDELRALERDGGLPGPRLLLADNPLRCGCAARPLLAWL 445
Query: 197 ASTRVSLPEPDSIACASPPALQGVPVYRLPA--LPCAPPSVHLSAEPPLEAPGTPLRAGL 254
+ +P+ + CA+P AL P+ L L CA E EA G L A
Sbjct: 446 RNATERVPDSRRLRCAAPRALLDRPLLDLDGARLRCADSGADARGE-EAEAAGPELEASY 504
Query: 255 AF 256
F
Sbjct: 505 VF 506
>gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens]
Length = 545
Score = 93.2 bits (230), Expect = 8e-19
Identities = 67/188 (35%), Positives = 88/188 (46%), Gaps = 3/188 (1%)
Query: 52 NVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFI 111
N+T LSL N + VL G FA + L L HN++ TV G A LS L++L LS+N I
Sbjct: 266 NLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAI 325
Query: 112 SSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALS 171
+ P R+L L L + N L +L L L L ++ N+L TL G FD
Sbjct: 326 THLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNY 385
Query: 172 ALSHLQLYHNPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQG--VPVYRLPALP 229
L +L L+ NP+ C C L +L W L + CA P L+G VP L
Sbjct: 386 NLFNLALHGNPWQCDCHLAYLFNWLQQYTDRLLNIQTY-CAGPAYLKGQVVPALNEKQLV 444
Query: 230 CAPPSVHL 237
C HL
Sbjct: 445 CPVTRDHL 452
Score = 68.2 bits (165), Expect = 3e-11
Identities = 39/126 (30%), Positives = 64/126 (50%)
Query: 56 LSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFP 115
L+L+ N + L G F + + SL L N+++ + L+ LK L+L+ N ++ P
Sbjct: 126 LTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLP 185
Query: 116 WSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSH 175
L++LQ LK+++N L LP+ G L L+ L +++N + L P F L L
Sbjct: 186 EELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLER 245
Query: 176 LQLYHN 181
L L N
Sbjct: 246 LWLQRN 251
Score = 66.6 bits (161), Expect = 8e-11
Identities = 48/143 (33%), Positives = 69/143 (48%), Gaps = 3/143 (2%)
Query: 42 LREVPEGLPANVT---TLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVL 98
L ++PE L +T TL LS N ++ L +G F + + L+L N + + P + L
Sbjct: 181 LAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQL 240
Query: 99 SQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNR 158
L+ L L N I+ P S +L L L + N L LP P L L + +N+
Sbjct: 241 FCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQ 300
Query: 159 LRTLAPGTFDALSALSHLQLYHN 181
L T+A GTF LS L L L +N
Sbjct: 301 LETVAEGTFAHLSNLRSLMLSYN 323
Score = 65.1 bits (157), Expect = 2e-10
Identities = 46/178 (25%), Positives = 75/178 (42%)
Query: 4 LRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKI 63
L WL+W L + +PC Q C+ +EL VP +P +
Sbjct: 2 LPGAWLLWTSLLLLARPAQPCPMGCDCFVQEVFCSDEELATVPLDIPPYTKNIIFVETSF 61
Query: 64 TVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLS 123
T L AF +T + + ++ P A L +L++L+++ + + + NL+
Sbjct: 62 TTLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLT 121
Query: 124 ALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHN 181
+L L +N N L +LP L L SL + N+L+ L F L+ L L L N
Sbjct: 122 SLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQN 179
Score = 56.6 bits (135), Expect = 8e-08
Identities = 43/146 (29%), Positives = 66/146 (45%), Gaps = 3/146 (2%)
Query: 39 YKELREVPEGL---PANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGAL 95
+ L +PEGL A + +L L N++ L R F +T + +L LA N + +
Sbjct: 130 FNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELF 189
Query: 96 AVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRIN 155
L+ L+ L LS+N +S P L +LQ L ++ N + LP L L L +
Sbjct: 190 HPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQ 249
Query: 156 NNRLRTLAPGTFDALSALSHLQLYHN 181
N + L F +L L+ L L N
Sbjct: 250 RNAITHLPLSIFASLGNLTFLSLQWN 275
Score = 56.2 bits (134), Expect = 1e-07
Identities = 38/134 (28%), Positives = 64/134 (47%), Gaps = 1/134 (0%)
Query: 48 GLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLS 107
GLP + L ++ + L F+++T + L L N + + G L+ L++L L
Sbjct: 95 GLP-RLEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQ 153
Query: 108 HNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTF 167
N + + P + L+ L+ L + N L LP + L L++L+++NN L L G F
Sbjct: 154 GNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVF 213
Query: 168 DALSALSHLQLYHN 181
L +L L L N
Sbjct: 214 GKLGSLQELFLDSN 227
Score = 55.5 bits (132), Expect = 2e-07
Identities = 39/130 (30%), Positives = 58/130 (44%)
Query: 52 NVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFI 111
++ TL+L+ N + L F +T + +L L++N + + G L L+ L L N I
Sbjct: 170 HLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNI 229
Query: 112 SSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALS 171
S P L L+ L + N + LP +L +L L + N LR L G F
Sbjct: 230 SELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTP 289
Query: 172 ALSHLQLYHN 181
L L L HN
Sbjct: 290 CLVGLSLTHN 299
>gi|59823631 G protein-coupled receptor 125 [Homo sapiens]
Length = 1321
Score = 93.2 bits (230), Expect = 8e-19
Identities = 63/212 (29%), Positives = 99/212 (46%), Gaps = 36/212 (16%)
Query: 37 CAYKELREV--PEGLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGA 94
C+ EL +V P+ LP TL LS NKI+ L+ G+F+ ++ + L L +N + +++PGA
Sbjct: 65 CSSLELAQVLPPDTLPNRTVTLILSNNKISELKNGSFSGLSLLERLDLRNNLISSIDPGA 124
Query: 95 LAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRI 154
LS LK LDL++N R+G L D L +L L +
Sbjct: 125 FWGLSSLKRLDLTNN------------------------RIGCLNADIFRGLTNLVRLNL 160
Query: 155 NNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAASTRVSLPEPDSIACASP 214
+ N +L+ GTFD L++L L+ C C ++W+ W +++ + C P
Sbjct: 161 SGNLFSSLSQGTFDYLASLRSLEFQTEYLLCDCNILWMHRWVKEKNITVRD---TRCVYP 217
Query: 215 PALQGVPVYRLPALPCAPPSVHLSAEPPLEAP 246
+LQ PV L+ +PPLE P
Sbjct: 218 KSLQAQPV-------TGVKQELLTCDPPLELP 242
>gi|157694513 leucine-rich repeat-containing G protein-coupled
receptor 4 [Homo sapiens]
Length = 951
Score = 92.8 bits (229), Expect = 1e-18
Identities = 64/181 (35%), Positives = 90/181 (49%), Gaps = 10/181 (5%)
Query: 8 WLVWALLGVAGS-------CPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSA 60
+L LLG AG C PC+C + DC+ K L VPEGL A L +S
Sbjct: 10 FLALGLLGSAGPSGAAPPLCAAPCSCD---GDRRVDCSGKGLTAVPEGLSAFTQALDISM 66
Query: 61 NKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLR 120
N IT L AF + + L LA N++ + P AL+ L +LK L L +N + + P +R
Sbjct: 67 NNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIR 126
Query: 121 NLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYH 180
LSALQ L+++ N + S+P D+ L LR L +++N L + L L L L
Sbjct: 127 GLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLAL 186
Query: 181 N 181
N
Sbjct: 187 N 187
Score = 67.8 bits (164), Expect = 4e-11
Identities = 54/170 (31%), Positives = 78/170 (45%), Gaps = 30/170 (17%)
Query: 41 ELREVPE----GLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALA 96
+L+ VP GL A + +L L AN IT + +F + Q+ LWL N + V L+
Sbjct: 116 QLKTVPSEAIRGLSA-LQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLS 174
Query: 97 VLSQLKNLDLSHNFISSFPWSDLRNLSA------------------------LQLLKMNH 132
L L+ L L+ N ISS P NLS+ L+ L +N+
Sbjct: 175 NLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNY 234
Query: 133 NRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNP 182
N LG P+ A+ ALP L+ L ++N + + G FD L + LY NP
Sbjct: 235 NNLGEFPQ-AIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNP 283
Score = 51.2 bits (121), Expect = 3e-06
Identities = 31/105 (29%), Positives = 55/105 (52%), Gaps = 3/105 (2%)
Query: 26 CVDKYAHQFADCAYKELREVPE--GLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLA 83
C ++ + D +Y +R++P G A + +SL N+I ++ G F + + L L+
Sbjct: 339 CQEQKMLRTLDLSYNNIRDLPSFNGCHA-LEEISLQRNQIYQIKEGTFQGLISLRILDLS 397
Query: 84 HNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLL 128
N + + A A L + NLD+S N ++SFP L L+ L+L+
Sbjct: 398 RNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQLKLV 442
Score = 42.7 bits (99), Expect = 0.001
Identities = 42/174 (24%), Positives = 70/174 (40%), Gaps = 27/174 (15%)
Query: 36 DCAYKELREVPEGLPA--NVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPG 93
D Y L E P+ + A ++ L +N I+V+ GAF + ++ L N + V
Sbjct: 231 DLNYNNLGEFPQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNS 290
Query: 94 ALAVLSQL-----------------------KNLDLSHNFISSFPWSDLRNLSALQLLKM 130
A LS L ++L L+ ISS P + + L+ L +
Sbjct: 291 AFHNLSDLHSLVIRGASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDL 350
Query: 131 NHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFH 184
++N + LP + L + + N++ + GTF L +L L L N H
Sbjct: 351 SYNNIRDLP--SFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIH 402
Score = 40.0 bits (92), Expect = 0.008
Identities = 39/134 (29%), Positives = 56/134 (41%), Gaps = 5/134 (3%)
Query: 55 TLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSF 114
TL LS N I L +F + + L N++ ++ G L L+ LDLS N I
Sbjct: 347 TLDLSYNNIRDLP--SFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEI 404
Query: 115 PWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLR-TLAPGTFDALSAL 173
L + L ++ N L S P + L L L+ + N +L+ LA F L +L
Sbjct: 405 HSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQLK--LVGNFKLKEALAAKDFVNLRSL 462
Query: 174 SHLQLYHNPFHCGC 187
S Y GC
Sbjct: 463 SVPYAYQCCAFWGC 476
>gi|62988340 leucine rich repeat containing 22 [Homo sapiens]
Length = 550
Score = 92.0 bits (227), Expect = 2e-18
Identities = 85/380 (22%), Positives = 146/380 (38%), Gaps = 67/380 (17%)
Query: 20 CPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRGAFADVTQVTS 79
C C C ++ + C L ++P L + + + + + +G+F +++ +
Sbjct: 24 CLPGCTCSEESFGRTLQCTSVSLGKIPGNLSEEFKQVRIENSPLFEMPQGSFINMSTLEY 83
Query: 80 LWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLP 139
LWL N + + GAL L +L+ L L N + S PW+ R L++L + N++ +LP
Sbjct: 84 LWLNFNNISVIHLGALEHLPELRELRLEGNKLCSVPWTAFRATPLLRVLDLKRNKIDALP 143
Query: 140 RDALGALPDLRSLRINNNRLRTLAPGTF----------------DALSALSHLQLYHNPF 183
AL L L L +++NRL ++ F + LS+L + L+ NP+
Sbjct: 144 ELALQFLVSLTYLDLSSNRLTVVSKSVFLNWPAYQKCRQPDCGAEILSSLV-VALHDNPW 202
Query: 184 HCGCGLVWLQAWAASTRVSLPEPDS-IACASPPALQGVPVYRLPALPCAPPSVHLSAEPP 242
C C L L + S + + +S + C P + G + C P +
Sbjct: 203 VCDCRLRGLVQFVKSITLPVILVNSYLICQGPLSKAGQLFHETELSACMKPQI------S 256
Query: 243 LEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEGEG 302
+ +RAG L C+A P+P + W P + E D + + GE
Sbjct: 257 TPSANITIRAGQNVTLRCLAQASPSPSIAWTY----------PLSMWREFDVLTSSTGED 306
Query: 303 EGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNELG 362
A L +P ++G YTC A N +G
Sbjct: 307 --------------------------------TALSELAIPAAHLVDSGNYTCMASNSIG 334
Query: 363 ANSTSIRVAVAATGPPKHAP 382
++ I + V HAP
Sbjct: 335 KSNLVISLHV-QPAQALHAP 353
Score = 33.5 bits (75), Expect = 0.74
Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 8/67 (11%)
Query: 549 GVNAYWFRGLRPGTNYSVCLALAGEACHVQ--VVFSTKKELPSL-----LVIVAVSVFLL 601
G+N Y L PGT Y CL+L G+ H V F T ++ L L+ V V V +
Sbjct: 414 GINTYAVDDLLPGTKYEACLSLEGQPPHQGQCVAFVTGRDAGGLEAREHLLHVTV-VLCV 472
Query: 602 VLATVPL 608
VL VP+
Sbjct: 473 VLLAVPV 479
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,170,658
Number of Sequences: 37866
Number of extensions: 2019025
Number of successful extensions: 13500
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 269
Number of HSP's successfully gapped in prelim test: 369
Number of HSP's that attempted gapping in prelim test: 10165
Number of HSP's gapped (non-prelim): 2777
length of query: 745
length of database: 18,247,518
effective HSP length: 110
effective length of query: 635
effective length of database: 14,082,258
effective search space: 8942233830
effective search space used: 8942233830
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.