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Search of human proteins with 194272207
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194272207 actin binding LIM protein family, member 2 isoform
7 [Homo sapiens]
(470 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194272207 actin binding LIM protein family, member 2 isoform ... 989 0.0
gi|194272204 actin binding LIM protein family, member 2 isoform ... 971 0.0
gi|153792514 actin binding LIM protein family, member 2 isoform ... 947 0.0
gi|194272202 actin binding LIM protein family, member 2 isoform ... 942 0.0
gi|194272198 actin binding LIM protein family, member 2 isoform ... 917 0.0
gi|194272200 actin binding LIM protein family, member 2 isoform ... 916 0.0
gi|194272196 actin binding LIM protein family, member 2 isoform ... 830 0.0
gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens] 546 e-155
gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens] 546 e-155
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens] 531 e-151
gi|7662330 actin binding LIM protein family, member 3 [Homo sapi... 471 e-133
gi|51173717 actin-binding LIM protein 1 isoform s [Homo sapiens] 164 2e-40
gi|170932518 paxillin isoform 3 [Homo sapiens] 139 6e-33
gi|170932516 paxillin isoform 2 [Homo sapiens] 139 6e-33
gi|170932514 paxillin isoform 1 [Homo sapiens] 139 6e-33
gi|221316659 leupaxin isoform 1 [Homo sapiens] 115 1e-25
gi|4758670 leupaxin isoform 2 [Homo sapiens] 115 1e-25
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor... 111 2e-24
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo... 110 2e-24
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo... 110 2e-24
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo... 110 2e-24
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ... 109 6e-24
gi|109638745 transforming growth factor beta 1 induced transcrip... 108 8e-24
gi|21361591 transforming growth factor beta 1 induced transcript... 108 8e-24
gi|4505001 LIM domain kinase 1 [Homo sapiens] 99 8e-21
gi|54112385 four and a half LIM domains 3 [Homo sapiens] 97 2e-20
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 92 1e-18
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 92 1e-18
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 92 1e-18
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 92 1e-18
>gi|194272207 actin binding LIM protein family, member 2 isoform 7
[Homo sapiens]
Length = 470
Score = 989 bits (2558), Expect = 0.0
Identities = 470/470 (100%), Positives = 470/470 (100%)
Query: 1 MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1 MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
Query: 61 GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61 GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGESPQLLSPTPTE 360
AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGESPQLLSPTPTE
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGESPQLLSPTPTE 360
Query: 361 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRKQK 420
GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRKQK
Sbjct: 361 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRKQK 420
Query: 421 SSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSREWFF 470
SSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSREWFF
Sbjct: 421 SSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSREWFF 470
>gi|194272204 actin binding LIM protein family, member 2 isoform 5
[Homo sapiens]
Length = 531
Score = 971 bits (2509), Expect = 0.0
Identities = 464/466 (99%), Positives = 465/466 (99%), Gaps = 1/466 (0%)
Query: 1 MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1 MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
Query: 61 GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61 GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGESPQLLSPTPTE 360
AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGESPQLLSPTPTE
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGESPQLLSPTPTE 360
Query: 361 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRKQK 420
GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRK K
Sbjct: 361 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRK-K 419
Query: 421 SSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSR 466
SSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS+
Sbjct: 420 SSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSQ 465
>gi|153792514 actin binding LIM protein family, member 2 isoform 6
[Homo sapiens]
Length = 521
Score = 947 bits (2447), Expect = 0.0
Identities = 454/466 (97%), Positives = 455/466 (97%), Gaps = 11/466 (2%)
Query: 1 MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1 MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
Query: 61 GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61 GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGESPQLLSPTPTE 360
AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYG E
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYG-----------E 349
Query: 361 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRKQK 420
GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRKQK
Sbjct: 350 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRKQK 409
Query: 421 SSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSR 466
SSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS+
Sbjct: 410 SSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSQ 455
>gi|194272202 actin binding LIM protein family, member 2 isoform 4
[Homo sapiens]
Length = 559
Score = 942 bits (2434), Expect = 0.0
Identities = 454/466 (97%), Positives = 454/466 (97%), Gaps = 12/466 (2%)
Query: 1 MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1 MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
Query: 61 GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61 GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGESPQLLSPTPTE 360
AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYG E
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYG-----------E 349
Query: 361 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRKQK 420
GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRK K
Sbjct: 350 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRK-K 408
Query: 421 SSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSR 466
SSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSR
Sbjct: 409 SSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSR 454
>gi|194272198 actin binding LIM protein family, member 2 isoform 2
[Homo sapiens]
Length = 611
Score = 917 bits (2371), Expect = 0.0
Identities = 454/518 (87%), Positives = 454/518 (87%), Gaps = 64/518 (12%)
Query: 1 MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1 MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
Query: 61 GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61 GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGESPQLLSPTPTE 360
AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGE
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGE----------- 349
Query: 361 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRP-------------------- 400
GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRP
Sbjct: 350 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPGSESGRSTPSLSVLSDSKPP 409
Query: 401 --------------------------------AARRSDGEDGSLDQDNRKQKSSWLMLKG 428
AARRSDGEDGSLDQDNRK KSSWLMLKG
Sbjct: 410 PSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHAARRSDGEDGSLDQDNRK-KSSWLMLKG 468
Query: 429 DADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSR 466
DADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSR
Sbjct: 469 DADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSR 506
>gi|194272200 actin binding LIM protein family, member 2 isoform 3
[Homo sapiens]
Length = 572
Score = 916 bits (2367), Expect = 0.0
Identities = 453/518 (87%), Positives = 454/518 (87%), Gaps = 64/518 (12%)
Query: 1 MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1 MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
Query: 61 GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61 GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGESPQLLSPTPTE 360
AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGE
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGE----------- 349
Query: 361 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRP-------------------- 400
GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRP
Sbjct: 350 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPGSESGRSTPSLSVLSDSKPP 409
Query: 401 --------------------------------AARRSDGEDGSLDQDNRKQKSSWLMLKG 428
AARRSDGEDGSLDQDNRK KSSWLMLKG
Sbjct: 410 PSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHAARRSDGEDGSLDQDNRK-KSSWLMLKG 468
Query: 429 DADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSR 466
DADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS+
Sbjct: 469 DADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSQ 506
>gi|194272196 actin binding LIM protein family, member 2 isoform 1
[Homo sapiens]
Length = 645
Score = 830 bits (2144), Expect = 0.0
Identities = 425/541 (78%), Positives = 438/541 (80%), Gaps = 76/541 (14%)
Query: 1 MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1 MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
Query: 61 GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61 GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYI--------SHSAGDR--QSYGES 350
AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYI S+ GD+ +SY +
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQC 360
Query: 351 PQLLSPTPTEGDQDDRSYKQCRT----SSPSSTGSVSL---------------------- 384
+ SP+ T R R+ S P+ T SV
Sbjct: 361 -RTSSPSSTGSVSLGRYTPTSRSPQHYSRPAGTVSVGTSSCLSLSQHPSPTSVFRHHYIP 419
Query: 385 -------GRYTPT--------------SRSPQHYSRP------------------AARRS 405
GR TP+ ++P+H+ P AARRS
Sbjct: 420 YFRGSESGRSTPSLSVLSDSKPPPSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHAARRS 479
Query: 406 DGEDGSLDQDNRKQKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS 465
DGEDGSLDQDNRKQKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS
Sbjct: 480 DGEDGSLDQDNRKQKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS 539
Query: 466 R 466
R
Sbjct: 540 R 540
>gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]
Length = 718
Score = 546 bits (1407), Expect = e-155
Identities = 257/416 (61%), Positives = 311/416 (74%), Gaps = 12/416 (2%)
Query: 4 VSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFF 63
V+ PQ P EK I C+ CG CKGEVLRVQ K+FHIKCF CK CGCDLA+GGFF
Sbjct: 22 VAHPQDPHHPSEKP---VIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFF 78
Query: 64 VRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVT 123
++ GEY+CTLDYQR+YGTRC C +F+EGEVV+ALGKTYHP+CF C +C+ PFPPGDRVT
Sbjct: 79 IKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVT 138
Query: 124 FNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC 183
FNG++C+CQ C+ P+S SS + +C GCG +IKNGQAL+ALDK WHLGCFKCKSC
Sbjct: 139 FNGRDCLCQLCAQPMS--SSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSC 196
Query: 184 GKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQ 243
GK+L EYISKDG PYCE DY FG++C++C ++ITG+VLEAG+KHYHPSCA C RC Q
Sbjct: 197 GKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQ 256
Query: 244 MFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKL 303
MF EGEEMYLQGS++WHP C+Q+ +TE++ + TRTSSESI S P SS GSP IYAK+
Sbjct: 257 MFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKV 316
Query: 304 GGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGD---RQSYGESPQLLSPTPT- 359
EILDY+DLAA+PK KAIYDI+RPD+I+Y P+ + D RQS GESP+ LSPTP+
Sbjct: 317 DNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQERQSLGESPRTLSPTPSA 376
Query: 360 EGDQDDRSYKQCRTSSPSSTGSVSLGR--YTP-TSRSPQHYSRPAARRSDGEDGSL 412
EG QD R R++S S S R YTP TSRSPQH+ RP S G + L
Sbjct: 377 EGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPGNEPSSGRNSPL 432
>gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens]
Length = 778
Score = 546 bits (1407), Expect = e-155
Identities = 257/416 (61%), Positives = 311/416 (74%), Gaps = 12/416 (2%)
Query: 4 VSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFF 63
V+ PQ P EK I C+ CG CKGEVLRVQ K+FHIKCF CK CGCDLA+GGFF
Sbjct: 82 VAHPQDPHHPSEKP---VIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFF 138
Query: 64 VRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVT 123
++ GEY+CTLDYQR+YGTRC C +F+EGEVV+ALGKTYHP+CF C +C+ PFPPGDRVT
Sbjct: 139 IKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVT 198
Query: 124 FNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC 183
FNG++C+CQ C+ P+S SS + +C GCG +IKNGQAL+ALDK WHLGCFKCKSC
Sbjct: 199 FNGRDCLCQLCAQPMS--SSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSC 256
Query: 184 GKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQ 243
GK+L EYISKDG PYCE DY FG++C++C ++ITG+VLEAG+KHYHPSCA C RC Q
Sbjct: 257 GKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQ 316
Query: 244 MFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKL 303
MF EGEEMYLQGS++WHP C+Q+ +TE++ + TRTSSESI S P SS GSP IYAK+
Sbjct: 317 MFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKV 376
Query: 304 GGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGD---RQSYGESPQLLSPTPT- 359
EILDY+DLAA+PK KAIYDI+RPD+I+Y P+ + D RQS GESP+ LSPTP+
Sbjct: 377 DNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQERQSLGESPRTLSPTPSA 436
Query: 360 EGDQDDRSYKQCRTSSPSSTGSVSLGR--YTP-TSRSPQHYSRPAARRSDGEDGSL 412
EG QD R R++S S S R YTP TSRSPQH+ RP S G + L
Sbjct: 437 EGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPGNEPSSGRNSPL 492
>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
Length = 746
Score = 531 bits (1368), Expect = e-151
Identities = 257/444 (57%), Positives = 311/444 (70%), Gaps = 40/444 (9%)
Query: 4 VSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFF 63
V+ PQ P EK I C+ CG CKGEVLRVQ K+FHIKCF CK CGCDLA+GGFF
Sbjct: 22 VAHPQDPHHPSEKP---VIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFF 78
Query: 64 VRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVT 123
++ GEY+CTLDYQR+YGTRC C +F+EGEVV+ALGKTYHP+CF C +C+ PFPPGDRVT
Sbjct: 79 IKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVT 138
Query: 124 FNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC 183
FNG++C+CQ C+ P+S SS + +C GCG +IKNGQAL+ALDK WHLGCFKCKSC
Sbjct: 139 FNGRDCLCQLCAQPMS--SSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSC 196
Query: 184 GKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQ 243
GK+L EYISKDG PYCE DY FG++C++C ++ITG+VLEAG+KHYHPSCA C RC Q
Sbjct: 197 GKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQ 256
Query: 244 MFAEGEEMYLQGSSIWHPACRQAARTEDRNK----------------------------E 275
MF EGEEMYLQGS++WHP C+Q+ +TE++ +
Sbjct: 257 MFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRLPNIRRSSSDFFYSKSLIRRTGRSPSLQP 316
Query: 276 TRTSSESIISVPASSTSGSPSRVIYAKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSP 335
TRTSSESI S P SS GSP IYAK+ EILDY+DLAA+PK KAIYDI+RPD+I+Y P
Sbjct: 317 TRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEP 376
Query: 336 YISHSAGD---RQSYGESPQLLSPTPT-EGDQDDRSYKQCRTSSPSSTGSVSLGR--YTP 389
+ + D RQS GESP+ LSPTP+ EG QD R R++S S S R YTP
Sbjct: 377 FYTSGYDDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTP 436
Query: 390 -TSRSPQHYSRPAARRSDGEDGSL 412
TSRSPQH+ RP S G + L
Sbjct: 437 TTSRSPQHFHRPGNEPSSGRNSPL 460
>gi|7662330 actin binding LIM protein family, member 3 [Homo
sapiens]
Length = 683
Score = 471 bits (1213), Expect = e-133
Identities = 231/407 (56%), Positives = 290/407 (71%), Gaps = 14/407 (3%)
Query: 16 KSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDY 75
+ S I C CG+ CKGEV+RV + +FHI+CF C+ CGC LA+ GFF + EYICT DY
Sbjct: 15 RGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDY 74
Query: 76 QRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCS 135
Q+LYGTRC SC FI GEV+SALG+TYHP CFVC++CR PFP GD+VTF+GKEC+CQ CS
Sbjct: 75 QQLYGTRCDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCS 134
Query: 136 LPVSVGSSAHLS-QGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISK 194
S+ SS + +G C GC EIK+GQ+L+ALDK WH+ CFKC++C +L EYISK
Sbjct: 135 Q--SMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQTCSVILTGEYISK 192
Query: 195 DGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQ 254
DG+PYCE+DYHA+FGI+C++C++YI+GRVLEAG KHYHP+CA CVRC QMF EGEEMYL
Sbjct: 193 DGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLT 252
Query: 255 GSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEILDYRDLA 314
GS +WHP C+QAAR E + K RTS SI P S+ GSP+RVI AK+ EIL+Y+DLA
Sbjct: 253 GSEVWHPICKQAARAEKKLKHRRTSETSI--SPPGSSIGSPNRVICAKVDNEILNYKDLA 310
Query: 315 ALPKSKAIYDIDRPDMISYSP---YISHSAGDRQSYGESPQLLSPTPTEGDQDDRSYKQC 371
ALPK K+IY++ RPD+ISY P Y+S +R YGES LSP ++ ++ +Q
Sbjct: 311 ALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPY-SQDIYENLDLRQR 369
Query: 372 RTSSPSSTGSVSLGR--YTPT-SRSPQHYSR--PAARRSDGEDGSLD 413
R SSP S + R +PT SRSP HY R P + RS LD
Sbjct: 370 RASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGPESGRSSPYHSQLD 416
>gi|51173717 actin-binding LIM protein 1 isoform s [Homo sapiens]
Length = 455
Score = 164 bits (415), Expect = 2e-40
Identities = 96/192 (50%), Positives = 117/192 (60%), Gaps = 35/192 (18%)
Query: 244 MFAEGEEMYLQGSSIWHPACRQAARTEDRNK----------------------------E 275
MF EGEEMYLQGS++WHP C+Q+ +TE++ +
Sbjct: 1 MFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRLPNIRRSSSDFFYSKSLIRRTGRSPSLQP 60
Query: 276 TRTSSESIISVPASSTSGSPSRVIYAKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSP 335
TRTSSESI S P SS GSP IYAK+ EILDY+DLAA+PK KAIYDI+RPD+I+Y P
Sbjct: 61 TRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEP 120
Query: 336 YISHSAGD---RQSYGESPQLLSPTPT-EGDQDDRSYKQCRTSSPSSTGSVSLGR--YTP 389
+ + D RQS GESP+ LSPTP+ EG QD R R++S S S R YTP
Sbjct: 121 FYTSGYDDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTP 180
Query: 390 -TSRSPQHYSRP 400
TSRSPQH+ RP
Sbjct: 181 TTSRSPQHFHRP 192
>gi|170932518 paxillin isoform 3 [Homo sapiens]
Length = 424
Score = 139 bits (350), Expect = 6e-33
Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
+C C G+V+ K +H + FVC C ++ FF R G+ C DY L+ R
Sbjct: 190 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249
Query: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
C+ C+ I +VV+AL +T+HP+ F CA C F P +GK C+K
Sbjct: 250 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 299
Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201
+ CGGC I + AL+ WH CF C+ C +N + DG PYCE
Sbjct: 300 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 357
Query: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
YH + G C C+K ITGR + A K +HP +C C + +G
Sbjct: 358 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 404
Score = 30.0 bits (66), Expect = 4.7
Identities = 16/57 (28%), Positives = 25/57 (43%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
LC+ C G + K FH + FVC C L +G F + + C + +L+
Sbjct: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
>gi|170932516 paxillin isoform 2 [Homo sapiens]
Length = 557
Score = 139 bits (350), Expect = 6e-33
Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
+C C G+V+ K +H + FVC C ++ FF R G+ C DY L+ R
Sbjct: 323 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382
Query: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
C+ C+ I +VV+AL +T+HP+ F CA C F P +GK C+K
Sbjct: 383 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 432
Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201
+ CGGC I + AL+ WH CF C+ C +N + DG PYCE
Sbjct: 433 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 490
Query: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
YH + G C C+K ITGR + A K +HP +C C + +G
Sbjct: 491 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 537
Score = 30.0 bits (66), Expect = 4.7
Identities = 16/57 (28%), Positives = 25/57 (43%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
LC+ C G + K FH + FVC C L +G F + + C + +L+
Sbjct: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
>gi|170932514 paxillin isoform 1 [Homo sapiens]
Length = 591
Score = 139 bits (350), Expect = 6e-33
Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
+C C G+V+ K +H + FVC C ++ FF R G+ C DY L+ R
Sbjct: 357 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 416
Query: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
C+ C+ I +VV+AL +T+HP+ F CA C F P +GK C+K
Sbjct: 417 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 466
Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201
+ CGGC I + AL+ WH CF C+ C +N + DG PYCE
Sbjct: 467 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 524
Query: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
YH + G C C+K ITGR + A K +HP +C C + +G
Sbjct: 525 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 571
Score = 30.0 bits (66), Expect = 4.7
Identities = 16/57 (28%), Positives = 25/57 (43%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
LC+ C G + K FH + FVC C L +G F + + C + +L+
Sbjct: 534 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590
>gi|221316659 leupaxin isoform 1 [Homo sapiens]
Length = 391
Score = 115 bits (287), Expect = 1e-25
Identities = 68/226 (30%), Positives = 99/226 (43%), Gaps = 13/226 (5%)
Query: 24 CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRC 83
C +C G+V+ + +H + FVC C ++ FF R G C DY +L+ RC
Sbjct: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRC 216
Query: 84 FSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSS 143
C I +V++A+ +T+HP+ F C+ C F G E +K P
Sbjct: 217 AYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVF---------GAEGFHEKDKKPYC--RK 265
Query: 144 AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCEA 202
L+ CGGC + L A+D WH CF C C + DG P+CE
Sbjct: 266 DFLAMFSPKCGGCNRPVLENY-LSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCEL 324
Query: 203 DYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
YH + G C C + ITGR + A +HP +C C ++G
Sbjct: 325 HYHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKG 370
Score = 87.8 bits (216), Expect = 2e-17
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
C SC + I G+V+ ALG+++HP+ FVC C+ G ++ L
Sbjct: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEI---------GSSPFFERSGLAYCPND 207
Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAE-YISKDGLPYCE 201
L C C I + + L A+++ WH F C CG++ AE + KD PYC
Sbjct: 208 YHQLFSP--RCAYCAAPILD-KVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCR 264
Query: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQG 255
D+ A F +C C + + L A + +HP C +C C F+ G L G
Sbjct: 265 KDFLAMFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDG 318
Score = 75.9 bits (185), Expect = 8e-14
Identities = 40/111 (36%), Positives = 47/111 (42%), Gaps = 1/111 (0%)
Query: 24 CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRC 83
C C L D +H +CFVC C + G FF G C L Y GT C
Sbjct: 275 CGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLC 334
Query: 84 FSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKC 134
C Q I G +SA+G +HP+ FVCA C G N K CQ C
Sbjct: 335 HGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDK-TYCQPC 384
Score = 33.1 bits (74), Expect = 0.56
Identities = 16/57 (28%), Positives = 26/57 (45%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
LC+ CG G + FH + FVC C L++G F + + C + +L+
Sbjct: 333 LCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
>gi|4758670 leupaxin isoform 2 [Homo sapiens]
Length = 386
Score = 115 bits (287), Expect = 1e-25
Identities = 68/226 (30%), Positives = 99/226 (43%), Gaps = 13/226 (5%)
Query: 24 CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRC 83
C +C G+V+ + +H + FVC C ++ FF R G C DY +L+ RC
Sbjct: 152 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRC 211
Query: 84 FSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSS 143
C I +V++A+ +T+HP+ F C+ C F G E +K P
Sbjct: 212 AYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVF---------GAEGFHEKDKKPYC--RK 260
Query: 144 AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCEA 202
L+ CGGC + L A+D WH CF C C + DG P+CE
Sbjct: 261 DFLAMFSPKCGGCNRPVLENY-LSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCEL 319
Query: 203 DYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
YH + G C C + ITGR + A +HP +C C ++G
Sbjct: 320 HYHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKG 365
Score = 87.8 bits (216), Expect = 2e-17
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
C SC + I G+V+ ALG+++HP+ FVC C+ G ++ L
Sbjct: 152 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEI---------GSSPFFERSGLAYCPND 202
Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAE-YISKDGLPYCE 201
L C C I + + L A+++ WH F C CG++ AE + KD PYC
Sbjct: 203 YHQLFSP--RCAYCAAPILD-KVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCR 259
Query: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQG 255
D+ A F +C C + + L A + +HP C +C C F+ G L G
Sbjct: 260 KDFLAMFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDG 313
Score = 75.9 bits (185), Expect = 8e-14
Identities = 40/111 (36%), Positives = 47/111 (42%), Gaps = 1/111 (0%)
Query: 24 CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRC 83
C C L D +H +CFVC C + G FF G C L Y GT C
Sbjct: 270 CGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLC 329
Query: 84 FSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKC 134
C Q I G +SA+G +HP+ FVCA C G N K CQ C
Sbjct: 330 HGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDK-TYCQPC 379
Score = 33.1 bits (74), Expect = 0.56
Identities = 16/57 (28%), Positives = 26/57 (45%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
LC+ CG G + FH + FVC C L++G F + + C + +L+
Sbjct: 328 LCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 384
>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
[Homo sapiens]
Length = 365
Score = 111 bits (277), Expect = 2e-24
Identities = 83/295 (28%), Positives = 116/295 (39%), Gaps = 61/295 (20%)
Query: 6 QPQAAPSPLEKSPSTAILCNTCGNVCKGE------VLRVQDKYFHIKCFVCKACGCDLAE 59
Q + +P P + S A+ C C+ ++ + +H CFVC C E
Sbjct: 18 QHRQSPPPATGNMSDALANAVCQR-CQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPE 76
Query: 60 GGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVC------- 112
G F+ +G C D+Q L+ C SC +FI G V+ A+ +HP CF C +C
Sbjct: 77 GLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADL 136
Query: 113 --------RLPFPPGDRVTFNG-KECMCQKCSL-----PVSVGSSA-------------- 144
L P +R G + +CQ+C L P+ S A
Sbjct: 137 GFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKE 196
Query: 145 -----------------HLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-L 186
H G+ CG C I+ G+ + AL K WH+ F C C K
Sbjct: 197 LTAEARELKGELYCLPCHDKMGVPICGACRRPIE-GRVVNALGKQWHVEHFVCAKCEKPF 255
Query: 187 LNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241
L + K GL YCE Y+ FG C +C I G V+ A K + SC C C
Sbjct: 256 LGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTC 310
Score = 71.6 bits (174), Expect = 1e-12
Identities = 32/112 (28%), Positives = 54/112 (48%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
+C C +G V+ K +H++ FVC C + ++G C Y +L+G
Sbjct: 221 ICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDV 280
Query: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKC 134
C++C IEG+VVSAL K + CF C+ C ++ + +C++C
Sbjct: 281 CYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRC 332
Score = 53.9 bits (128), Expect = 3e-07
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Query: 173 WHLGCFKCKSCGKLL-NAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHY 231
+H CF C C + + +G YCE D+ F C SC ++I GRV++A ++
Sbjct: 60 YHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNW 119
Query: 232 HPSCALCVRCGQMFAE 247
HP C C C A+
Sbjct: 120 HPGCFRCELCDVELAD 135
>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
1 [Homo sapiens]
Length = 363
Score = 110 bits (276), Expect = 2e-24
Identities = 70/224 (31%), Positives = 97/224 (43%), Gaps = 19/224 (8%)
Query: 24 CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQR-----L 78
C +CG G V++ + +H CF C+ C +LA+ GF G ++C + R L
Sbjct: 98 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 157
Query: 79 YGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPV 138
C C I+ + + YHPD F C C G +T +E + LP
Sbjct: 158 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHC------GKELTAEARELKGELYCLP- 210
Query: 139 SVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGL 197
H G+ CG C I+ G+ + AL K WH+ F C C K L + K GL
Sbjct: 211 -----CHDKMGVPICGACRRPIE-GRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGL 264
Query: 198 PYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241
YCE Y+ FG C +C I G V+ A K + SC C C
Sbjct: 265 AYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTC 308
Score = 71.6 bits (174), Expect = 1e-12
Identities = 53/185 (28%), Positives = 80/185 (43%), Gaps = 17/185 (9%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
+C C V + L + +H F C CG +L ++ GE C + ++
Sbjct: 161 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPI 219
Query: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
C +C + IEG VV+ALGK +H + FVCA C PF G R C+
Sbjct: 220 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPF-LGHRHYEKKGLAYCE---------- 268
Query: 143 SAHLSQGLRS-CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK--LLNAEYISKDGLPY 199
H +Q C C + + G + AL+K W + CF C +C L +++ D P
Sbjct: 269 -THYNQLFGDVCYNC-SHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPV 326
Query: 200 CEADY 204
C+ Y
Sbjct: 327 CKRCY 331
Score = 56.2 bits (134), Expect = 6e-08
Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 25/168 (14%)
Query: 108 VCAVCRLPFPPGDRVTFNGKEC------MCQKCSLPVSVG---------SSAHLSQGLRS 152
VC C+ F P +R+ + E +C +C P G H Q L +
Sbjct: 36 VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFA 95
Query: 153 --CGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYHAKFG 209
CG CG E G+ + A++ +WH GCF+C+ C +L + ++ G C ++ +
Sbjct: 96 PCCGSCG-EFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 154
Query: 210 -----IRCDSCEKYITGRVLEAGEKHYHPSCALCVRCG-QMFAEGEEM 251
C C I + L YHP C CG ++ AE E+
Sbjct: 155 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAREL 202
>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
5 [Homo sapiens]
Length = 336
Score = 110 bits (276), Expect = 2e-24
Identities = 70/224 (31%), Positives = 97/224 (43%), Gaps = 19/224 (8%)
Query: 24 CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQR-----L 78
C +CG G V++ + +H CF C+ C +LA+ GF G ++C + R L
Sbjct: 71 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 130
Query: 79 YGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPV 138
C C I+ + + YHPD F C C G +T +E + LP
Sbjct: 131 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHC------GKELTAEARELKGELYCLP- 183
Query: 139 SVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGL 197
H G+ CG C I+ G+ + AL K WH+ F C C K L + K GL
Sbjct: 184 -----CHDKMGVPICGACRRPIE-GRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGL 237
Query: 198 PYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241
YCE Y+ FG C +C I G V+ A K + SC C C
Sbjct: 238 AYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTC 281
Score = 71.6 bits (174), Expect = 1e-12
Identities = 53/185 (28%), Positives = 80/185 (43%), Gaps = 17/185 (9%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
+C C V + L + +H F C CG +L ++ GE C + ++
Sbjct: 134 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPI 192
Query: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
C +C + IEG VV+ALGK +H + FVCA C PF G R C+
Sbjct: 193 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPF-LGHRHYEKKGLAYCE---------- 241
Query: 143 SAHLSQGLRS-CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK--LLNAEYISKDGLPY 199
H +Q C C + + G + AL+K W + CF C +C L +++ D P
Sbjct: 242 -THYNQLFGDVCYNC-SHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPV 299
Query: 200 CEADY 204
C+ Y
Sbjct: 300 CKRCY 304
Score = 56.2 bits (134), Expect = 6e-08
Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 25/168 (14%)
Query: 108 VCAVCRLPFPPGDRVTFNGKEC------MCQKCSLPVSVG---------SSAHLSQGLRS 152
VC C+ F P +R+ + E +C +C P G H Q L +
Sbjct: 9 VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFA 68
Query: 153 --CGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYHAKFG 209
CG CG E G+ + A++ +WH GCF+C+ C +L + ++ G C ++ +
Sbjct: 69 PCCGSCG-EFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 127
Query: 210 -----IRCDSCEKYITGRVLEAGEKHYHPSCALCVRCG-QMFAEGEEM 251
C C I + L YHP C CG ++ AE E+
Sbjct: 128 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAREL 175
>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
3 [Homo sapiens]
Length = 341
Score = 110 bits (276), Expect = 2e-24
Identities = 70/224 (31%), Positives = 97/224 (43%), Gaps = 19/224 (8%)
Query: 24 CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQR-----L 78
C +CG G V++ + +H CF C+ C +LA+ GF G ++C + R L
Sbjct: 76 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 135
Query: 79 YGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPV 138
C C I+ + + YHPD F C C G +T +E + LP
Sbjct: 136 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHC------GKELTAEARELKGELYCLP- 188
Query: 139 SVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGL 197
H G+ CG C I+ G+ + AL K WH+ F C C K L + K GL
Sbjct: 189 -----CHDKMGVPICGACRRPIE-GRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGL 242
Query: 198 PYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241
YCE Y+ FG C +C I G V+ A K + SC C C
Sbjct: 243 AYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTC 286
Score = 71.6 bits (174), Expect = 1e-12
Identities = 53/185 (28%), Positives = 80/185 (43%), Gaps = 17/185 (9%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
+C C V + L + +H F C CG +L ++ GE C + ++
Sbjct: 139 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPI 197
Query: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
C +C + IEG VV+ALGK +H + FVCA C PF G R C+
Sbjct: 198 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPF-LGHRHYEKKGLAYCE---------- 246
Query: 143 SAHLSQGLRS-CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK--LLNAEYISKDGLPY 199
H +Q C C + + G + AL+K W + CF C +C L +++ D P
Sbjct: 247 -THYNQLFGDVCYNC-SHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPV 304
Query: 200 CEADY 204
C+ Y
Sbjct: 305 CKRCY 309
Score = 56.2 bits (134), Expect = 6e-08
Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 25/168 (14%)
Query: 108 VCAVCRLPFPPGDRVTFNGKEC------MCQKCSLPVSVG---------SSAHLSQGLRS 152
VC C+ F P +R+ + E +C +C P G H Q L +
Sbjct: 14 VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFA 73
Query: 153 --CGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYHAKFG 209
CG CG E G+ + A++ +WH GCF+C+ C +L + ++ G C ++ +
Sbjct: 74 PCCGSCG-EFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 132
Query: 210 -----IRCDSCEKYITGRVLEAGEKHYHPSCALCVRCG-QMFAEGEEM 251
C C I + L YHP C CG ++ AE E+
Sbjct: 133 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAREL 180
>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
sapiens]
Length = 325
Score = 109 bits (272), Expect = 6e-24
Identities = 76/282 (26%), Positives = 114/282 (40%), Gaps = 61/282 (21%)
Query: 19 STAILCNTCGNVCKG------EVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICT 72
+ A+ TC CKG +++ + +H +CFVC C EG F+ +G C
Sbjct: 2 ANALASATCER-CKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 60
Query: 73 LDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCR---------------LPFP 117
D+Q L+ C C +FI G V+ A+ ++HP+CF C +C+ L P
Sbjct: 61 HDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP 120
Query: 118 PGDRVTFNG-KECMCQKCSLPV--------------------SVGSS------------- 143
+R G + +CQKC + + G
Sbjct: 121 CHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGELY 180
Query: 144 ---AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGLPY 199
H G+ CG C I+ G+ + A+ K WH+ F C C K L + + GL Y
Sbjct: 181 CLPCHDKMGVPICGACRRPIE-GRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAY 239
Query: 200 CEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241
CE Y+ FG C C + I G V+ A K + +C C C
Sbjct: 240 CETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTC 281
Score = 77.4 bits (189), Expect = 3e-14
Identities = 35/112 (31%), Positives = 56/112 (50%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
+C C +G V+ K +H++ FVC C + R+G C Y +L+G
Sbjct: 192 ICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDV 251
Query: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKC 134
CF C++ IEG+VVSAL K + +CF C+ C ++ + +C+KC
Sbjct: 252 CFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKC 303
Score = 53.5 bits (127), Expect = 4e-07
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Query: 173 WHLGCFKCKSCGKLL-NAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHY 231
+H CF C C + + +G YCE D+ F C C ++I GRV++A +
Sbjct: 31 YHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSW 90
Query: 232 HPSCALCVRCGQMFAE 247
HP C C C ++ A+
Sbjct: 91 HPECFRCDLCQEVLAD 106
>gi|109638745 transforming growth factor beta 1 induced transcript 1
isoform 1 [Homo sapiens]
Length = 461
Score = 108 bits (271), Expect = 8e-24
Identities = 70/242 (28%), Positives = 103/242 (42%), Gaps = 17/242 (7%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
LC +C G+V+ + +H + FVC C L FF + G C Y + R
Sbjct: 227 LCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR 286
Query: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKE--CMCQKCSLPVSV 140
C C+Q I ++V+ALG +HP+ F C C PF GD F+ +E C++ L +
Sbjct: 287 CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPF--GDE-GFHEREGRPYCRRDFLQLFA 343
Query: 141 GSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPY 199
C GC I + + AL WH CF C+ C + +G P
Sbjct: 344 ----------PRCQGCQGPILDNY-ISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPL 392
Query: 200 CEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIW 259
CE +HA+ G C +C +TGR + A + +HP C C + +G G
Sbjct: 393 CENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYC 452
Query: 260 HP 261
P
Sbjct: 453 QP 454
Score = 90.1 bits (222), Expect = 4e-18
Identities = 53/187 (28%), Positives = 83/187 (44%), Gaps = 13/187 (6%)
Query: 24 CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRC 83
C C + +++ ++H + F C +CG + GF R+G C D+ +L+ RC
Sbjct: 287 CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRC 346
Query: 84 FSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSS 143
C I +SAL +HPDCFVC C PF G G+ +C+ +
Sbjct: 347 QGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRP-LCE---------NH 396
Query: 144 AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGLPYCEA 202
H +G C CG + G+ + AL + +H F C C + L + + G PYC+
Sbjct: 397 FHARRG-SLCATCGLPV-TGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQP 454
Query: 203 DYHAKFG 209
+ FG
Sbjct: 455 CFLKLFG 461
Score = 36.6 bits (83), Expect = 0.050
Identities = 19/58 (32%), Positives = 26/58 (44%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYG 80
LC TCG G + + FH F C C L +G F R G+ C + +L+G
Sbjct: 404 LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLFG 461
>gi|21361591 transforming growth factor beta 1 induced transcript 1
isoform 2 [Homo sapiens]
Length = 444
Score = 108 bits (271), Expect = 8e-24
Identities = 70/242 (28%), Positives = 103/242 (42%), Gaps = 17/242 (7%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
LC +C G+V+ + +H + FVC C L FF + G C Y + R
Sbjct: 210 LCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR 269
Query: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKE--CMCQKCSLPVSV 140
C C+Q I ++V+ALG +HP+ F C C PF GD F+ +E C++ L +
Sbjct: 270 CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPF--GDE-GFHEREGRPYCRRDFLQLFA 326
Query: 141 GSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPY 199
C GC I + + AL WH CF C+ C + +G P
Sbjct: 327 ----------PRCQGCQGPILDNY-ISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPL 375
Query: 200 CEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIW 259
CE +HA+ G C +C +TGR + A + +HP C C + +G G
Sbjct: 376 CENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYC 435
Query: 260 HP 261
P
Sbjct: 436 QP 437
Score = 90.1 bits (222), Expect = 4e-18
Identities = 53/187 (28%), Positives = 83/187 (44%), Gaps = 13/187 (6%)
Query: 24 CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRC 83
C C + +++ ++H + F C +CG + GF R+G C D+ +L+ RC
Sbjct: 270 CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRC 329
Query: 84 FSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSS 143
C I +SAL +HPDCFVC C PF G G+ +C+ +
Sbjct: 330 QGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRP-LCE---------NH 379
Query: 144 AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGLPYCEA 202
H +G C CG + G+ + AL + +H F C C + L + + G PYC+
Sbjct: 380 FHARRG-SLCATCGLPV-TGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQP 437
Query: 203 DYHAKFG 209
+ FG
Sbjct: 438 CFLKLFG 444
Score = 36.6 bits (83), Expect = 0.050
Identities = 19/58 (32%), Positives = 26/58 (44%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYG 80
LC TCG G + + FH F C C L +G F R G+ C + +L+G
Sbjct: 387 LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLFG 444
>gi|4505001 LIM domain kinase 1 [Homo sapiens]
Length = 647
Score = 99.0 bits (245), Expect = 8e-21
Identities = 42/98 (42%), Positives = 57/98 (58%), Gaps = 1/98 (1%)
Query: 153 CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRC 212
C CG I +GQ L AL+ WH CF+C C L+ +Y KDG +C+ DY A++G C
Sbjct: 25 CASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQYYEKDGQLFCKKDYWARYGESC 84
Query: 213 DSCEKYIT-GRVLEAGEKHYHPSCALCVRCGQMFAEGE 249
C + IT G V+ AGE YHP C +C+ CG +G+
Sbjct: 85 HGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGDGD 122
Score = 65.5 bits (158), Expect = 1e-10
Identities = 48/172 (27%), Positives = 70/172 (40%), Gaps = 36/172 (20%)
Query: 23 LCNTCGN-VCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGT 81
+C +CG + G+ L+ + +H CF C C L+ ++ + G+ C DY YG
Sbjct: 24 VCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQ-YYEKDGQLFCKKDYWARYGE 82
Query: 82 RCFSC-DQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTF-NGKECMCQKC----- 134
C C +Q +G V+ A YHP+CF+C C GD T + C C
Sbjct: 83 SCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYCGHCYYQTV 142
Query: 135 ---------------SLP-----VSVGSSAHLSQGL-------RSCGGCGTE 159
LP VS+ +S+H +GL GCGTE
Sbjct: 143 VTPVIEQILPDSPGSHLPHTVTLVSIPASSHGKRGLSVSIDPPHGPPGCGTE 194
Score = 48.5 bits (114), Expect = 1e-05
Identities = 30/106 (28%), Positives = 46/106 (43%), Gaps = 13/106 (12%)
Query: 83 CFSCDQFI-EGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVG 141
C SC Q I +G+ + AL +H DCF C C + + C+K
Sbjct: 25 CASCGQRIYDGQYLQALNADWHADCFRCCDCSASL--SHQYYEKDGQLFCKK-------- 74
Query: 142 SSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLL 187
+ ++ SC GC +I G +VA + +H CF C +CG +
Sbjct: 75 --DYWARYGESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFI 118
>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
Length = 280
Score = 97.4 bits (241), Expect = 2e-20
Identities = 67/255 (26%), Positives = 107/255 (41%), Gaps = 34/255 (13%)
Query: 25 NTCGNVCK---------GEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDY 75
NT N C L +D++FH CF C C LA+ F + E +C Y
Sbjct: 34 NTFANTCAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCY 93
Query: 76 QRLYGTRCFSCDQFI--EGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQK 133
+ ++C +C + + + G+T+H CF+C+ C P V G C
Sbjct: 94 CSAFSSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAH-YCVP 152
Query: 134 CSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYI 192
C + ++ C C + G + D+ WH C C C L ++
Sbjct: 153 C----------YENKFAPRCARCSKTLTQG-GVTYRDQPWHRECLVCTGCQTPLAGQQFT 201
Query: 193 SKDGLPYCEADYHAKFGIRCDSCEKYIT----GRVLEAGEKHYHPSCALCVRC-----GQ 243
S+D PYC A + F +C SC++ I G+ + ++H+H +C C RC GQ
Sbjct: 202 SRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQ 261
Query: 244 MFA-EGEEMYLQGSS 257
F +G+++ QG S
Sbjct: 262 GFVPDGDQVLCQGCS 276
Score = 72.4 bits (176), Expect = 8e-13
Identities = 54/212 (25%), Positives = 77/212 (36%), Gaps = 20/212 (9%)
Query: 48 FVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFI--EGEVVSALGKTYHPD 105
F C C L + C Y + C C Q I + + + +H
Sbjct: 5 FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEG 64
Query: 106 CFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNG-Q 164
CF C C+ + T E +C C SA SQ C CG + G +
Sbjct: 65 CFRCCRCQRSL-ADEPFTCQDSELLCNDCY------CSAFSSQ----CSACGETVMPGSR 113
Query: 165 ALVALDKHWHLGCFKCKSCGKLLNA-EYISKDGLPYCEADYHAKFGIRCDSCEKYITGRV 223
L + WH CF C C + L + ++ G YC Y KF RC C K +T
Sbjct: 114 KLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGG 173
Query: 224 LEAGEKHYHPSCALCVRC-----GQMFAEGEE 250
+ ++ +H C +C C GQ F +E
Sbjct: 174 VTYRDQPWHRECLVCTGCQTPLAGQQFTSRDE 205
Score = 72.4 bits (176), Expect = 8e-13
Identities = 42/175 (24%), Positives = 68/175 (38%), Gaps = 10/175 (5%)
Query: 24 CNTCGNVCK--GEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGT 81
C+ CG L + +H CF+C C L F +G + C Y+ +
Sbjct: 101 CSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAP 160
Query: 82 RCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVG 141
RC C + + V+ + +H +C VC C+ P G + T ++ C C +
Sbjct: 161 RCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPL-AGQQFTSRDEDPYCVACFGELFAP 219
Query: 142 SSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDG 196
+ + + GG G+ + D+HWH CF C C L + DG
Sbjct: 220 KCSSCKRPIVGLGG-------GKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDG 267
Score = 41.2 bits (95), Expect = 0.002
Identities = 29/122 (23%), Positives = 38/122 (31%), Gaps = 36/122 (29%)
Query: 178 FKCKSCGK-LLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYI--TGRVLEAGEKHYHPS 234
F C C + L +YI D PYC Y F C C++ I R L ++H+H
Sbjct: 5 FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEG 64
Query: 235 CALCVRCGQMFAE---------------------------------GEEMYLQGSSIWHP 261
C C RC + A+ G G WH
Sbjct: 65 CFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWHE 124
Query: 262 AC 263
C
Sbjct: 125 HC 126
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 92.0 bits (227), Expect = 1e-18
Identities = 62/190 (32%), Positives = 90/190 (47%), Gaps = 19/190 (10%)
Query: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
C C+Q I G + ALGK++HP+ F CA C+ V G C+ C
Sbjct: 311 CAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGA-LYCELC-------- 361
Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGLPYCE 201
+ CG C +I G+ + AL + WH+ CF C +CGK + N + +DG PYCE
Sbjct: 362 --YEKFFAPECGRCQRKIL-GEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCE 418
Query: 202 ADYHAKFGIRCDSCEKYITG--RVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIW 259
DY+A FG C CE I LEA +H +C +C C + EG+ + +
Sbjct: 419 TDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESL-EGQTFFSKKDK-- 475
Query: 260 HPACRQAART 269
P C++ A +
Sbjct: 476 -PLCKKHAHS 484
Score = 85.1 bits (209), Expect = 1e-16
Identities = 57/187 (30%), Positives = 81/187 (43%), Gaps = 15/187 (8%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
+C C V +G L K +H + F C C +A GF +G C L Y++ +
Sbjct: 310 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPE 369
Query: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKE-CMCQKCSLPVSVG 141
C C + I GEV+SAL +T+H CFVC C P +G+ C +L ++
Sbjct: 370 CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTI- 428
Query: 142 SSAHLSQGLRSCGGCGTEIKNGQA-LVALDKHWHLGCFKCKSCGKLLNAE-YISKDGLPY 199
C GC I+ G L AL WH CF C C + L + + SK P
Sbjct: 429 -----------CHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPL 477
Query: 200 CEADYHA 206
C+ H+
Sbjct: 478 CKKHAHS 484
Score = 67.0 bits (162), Expect = 3e-11
Identities = 37/107 (34%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Query: 140 VGSSAHLSQGLRS--CGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDG 196
V + H+ G R+ C C I+ G LVAL K WH F C C + ++ + G
Sbjct: 296 VQRAEHIPAGKRTPMCAHCNQVIR-GPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKG 354
Query: 197 LPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQ 243
YCE Y F C C++ I G V+ A ++ +H SC +CV CG+
Sbjct: 355 ALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGK 401
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 92.0 bits (227), Expect = 1e-18
Identities = 62/190 (32%), Positives = 90/190 (47%), Gaps = 19/190 (10%)
Query: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
C C+Q I G + ALGK++HP+ F CA C+ V G C+ C
Sbjct: 420 CAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGA-LYCELC-------- 470
Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGLPYCE 201
+ CG C +I G+ + AL + WH+ CF C +CGK + N + +DG PYCE
Sbjct: 471 --YEKFFAPECGRCQRKIL-GEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCE 527
Query: 202 ADYHAKFGIRCDSCEKYITG--RVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIW 259
DY+A FG C CE I LEA +H +C +C C + EG+ + +
Sbjct: 528 TDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESL-EGQTFFSKKDK-- 584
Query: 260 HPACRQAART 269
P C++ A +
Sbjct: 585 -PLCKKHAHS 593
Score = 85.1 bits (209), Expect = 1e-16
Identities = 57/187 (30%), Positives = 81/187 (43%), Gaps = 15/187 (8%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
+C C V +G L K +H + F C C +A GF +G C L Y++ +
Sbjct: 419 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPE 478
Query: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKE-CMCQKCSLPVSVG 141
C C + I GEV+SAL +T+H CFVC C P +G+ C +L ++
Sbjct: 479 CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTI- 537
Query: 142 SSAHLSQGLRSCGGCGTEIKNGQA-LVALDKHWHLGCFKCKSCGKLLNAE-YISKDGLPY 199
C GC I+ G L AL WH CF C C + L + + SK P
Sbjct: 538 -----------CHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPL 586
Query: 200 CEADYHA 206
C+ H+
Sbjct: 587 CKKHAHS 593
Score = 67.0 bits (162), Expect = 3e-11
Identities = 37/107 (34%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Query: 140 VGSSAHLSQGLRS--CGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDG 196
V + H+ G R+ C C I+ G LVAL K WH F C C + ++ + G
Sbjct: 405 VQRAEHIPAGKRTPMCAHCNQVIR-GPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKG 463
Query: 197 LPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQ 243
YCE Y F C C++ I G V+ A ++ +H SC +CV CG+
Sbjct: 464 ALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGK 510
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 91.7 bits (226), Expect = 1e-18
Identities = 56/185 (30%), Positives = 79/185 (42%), Gaps = 13/185 (7%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
LC C NV +G L + +H + F C C LA+ F Q C Y++ +
Sbjct: 440 LCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPL 499
Query: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
C C+ I GEV+ AL +T+H CFVCA C+ PF E C+K
Sbjct: 500 CAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPF-GNSLFHMEDGEPYCEK--------- 549
Query: 143 SAHLSQGLRSCGGCGTEIKNGQALV-ALDKHWHLGCFKCKSCGKLLNAE-YISKDGLPYC 200
+++ C GC ++ G + AL WH CF C C L + + SK P C
Sbjct: 550 -DYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
Query: 201 EADYH 205
+ H
Sbjct: 609 KKHAH 613
Score = 84.3 bits (207), Expect = 2e-16
Identities = 55/190 (28%), Positives = 86/190 (45%), Gaps = 19/190 (10%)
Query: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
C C+ I G + A+G+++HP+ F CA C+ V C++C
Sbjct: 441 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVE-EQNNVYCERC-------- 491
Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLL-NAEYISKDGLPYCE 201
+ C C T+I G+ + AL + WH CF C +C K N+ + +DG PYCE
Sbjct: 492 --YEQFFAPLCAKCNTKIM-GEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCE 548
Query: 202 ADYHAKFGIRCDSCEKYITG--RVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIW 259
DY F +C C+ + + +EA +H +C +C C + EG+ Y S
Sbjct: 549 KDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVC-HVNLEGQPFY---SKKD 604
Query: 260 HPACRQAART 269
P C++ A T
Sbjct: 605 RPLCKKHAHT 614
Score = 79.0 bits (193), Expect = 9e-15
Identities = 37/96 (38%), Positives = 49/96 (51%), Gaps = 2/96 (2%)
Query: 21 AILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYG 80
A LC C GEV+ + +H CFVC AC F + GE C DY L+
Sbjct: 497 APLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFS 556
Query: 81 TRCFSCDQFIEG--EVVSALGKTYHPDCFVCAVCRL 114
T+C CD +E + + ALG T+H CF+CAVC +
Sbjct: 557 TKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHV 592
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 91.7 bits (226), Expect = 1e-18
Identities = 56/185 (30%), Positives = 79/185 (42%), Gaps = 13/185 (7%)
Query: 23 LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
LC C NV +G L + +H + F C C LA+ F Q C Y++ +
Sbjct: 550 LCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPL 609
Query: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
C C+ I GEV+ AL +T+H CFVCA C+ PF E C+K
Sbjct: 610 CAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPF-GNSLFHMEDGEPYCEK--------- 659
Query: 143 SAHLSQGLRSCGGCGTEIKNGQALV-ALDKHWHLGCFKCKSCGKLLNAE-YISKDGLPYC 200
+++ C GC ++ G + AL WH CF C C L + + SK P C
Sbjct: 660 -DYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 718
Query: 201 EADYH 205
+ H
Sbjct: 719 KKHAH 723
Score = 84.3 bits (207), Expect = 2e-16
Identities = 55/190 (28%), Positives = 86/190 (45%), Gaps = 19/190 (10%)
Query: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
C C+ I G + A+G+++HP+ F CA C+ V C++C
Sbjct: 551 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVE-EQNNVYCERC-------- 601
Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLL-NAEYISKDGLPYCE 201
+ C C T+I G+ + AL + WH CF C +C K N+ + +DG PYCE
Sbjct: 602 --YEQFFAPLCAKCNTKIM-GEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCE 658
Query: 202 ADYHAKFGIRCDSCEKYITG--RVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIW 259
DY F +C C+ + + +EA +H +C +C C + EG+ Y S
Sbjct: 659 KDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVC-HVNLEGQPFY---SKKD 714
Query: 260 HPACRQAART 269
P C++ A T
Sbjct: 715 RPLCKKHAHT 724
Score = 79.0 bits (193), Expect = 9e-15
Identities = 37/96 (38%), Positives = 49/96 (51%), Gaps = 2/96 (2%)
Query: 21 AILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYG 80
A LC C GEV+ + +H CFVC AC F + GE C DY L+
Sbjct: 607 APLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFS 666
Query: 81 TRCFSCDQFIEG--EVVSALGKTYHPDCFVCAVCRL 114
T+C CD +E + + ALG T+H CF+CAVC +
Sbjct: 667 TKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHV 702
Score = 30.4 bits (67), Expect = 3.6
Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 8/85 (9%)
Query: 324 DIDRPDMISYSPYISHSA--GDRQSYGESPQLLSPTP---TEGDQDDRSYK--QCRTSSP 376
D RP SYSP ++ S+ SY E P +P P T Y+ T SP
Sbjct: 359 DSPRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSP 418
Query: 377 SSTGSVSLGRYTPTSRSPQHYSRPA 401
S + S YTP S +P + PA
Sbjct: 419 SPGANYSPTPYTP-SPAPAYTPSPA 442
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,301,373
Number of Sequences: 37866
Number of extensions: 1092576
Number of successful extensions: 5598
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 132
Number of HSP's successfully gapped in prelim test: 389
Number of HSP's that attempted gapping in prelim test: 3715
Number of HSP's gapped (non-prelim): 1440
length of query: 470
length of database: 18,247,518
effective HSP length: 106
effective length of query: 364
effective length of database: 14,233,722
effective search space: 5181074808
effective search space used: 5181074808
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.