Search of human proteins with 194248072

Search of human proteins with 194248072

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]
         (641 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]              1261   0.0  
gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]              1261   0.0  
gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]          1130   0.0  
gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]       1103   0.0  
gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]                1070   0.0  
gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]      1064   0.0  
gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]       831   0.0  
gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]                 786   0.0  
gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]       567   e-162
gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens]      316   4e-86
gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]                 294   2e-79
gi|48928056 heat shock protein 70kDa family member 13 precursor ...   278   1e-74
gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens]            275   9e-74
gi|42544159 heat shock 105kD [Homo sapiens]                           269   7e-72
gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]          222   9e-58
gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]            222   9e-58
gi|38348298 ankyrin repeat domain 45 [Homo sapiens]                    44   6e-04
gi|9910266 kinesin family member 15 [Homo sapiens]                     41   0.003
gi|31317303 heat shock 70kD protein 12B [Homo sapiens]                 38   0.033
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    37   0.056
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    37   0.056
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    37   0.056
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    37   0.056
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    37   0.056
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     37   0.073
gi|148839339 nexilin (F actin binding protein) [Homo sapiens]          37   0.073
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    36   0.096
gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ...    35   0.16 
gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens]        35   0.21 
gi|130980075 centromere protein J [Homo sapiens]                       34   0.36 

>gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]
          Length = 641

 Score = 1261 bits (3263), Expect = 0.0
 Identities = 641/641 (100%), Positives = 641/641 (100%)

Query: 1   MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60
           MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
Sbjct: 1   MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60

Query: 61  LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEIS 120
           LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEIS
Sbjct: 61  LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEIS 120

Query: 121 SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA 180
           SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA
Sbjct: 121 SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA 180

Query: 181 IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH 240
           IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH
Sbjct: 181 IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH 240

Query: 241 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA 300
           FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA
Sbjct: 241 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA 300

Query: 301 RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN 360
           RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN
Sbjct: 301 RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN 360

Query: 361 KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI 420
           KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI
Sbjct: 361 KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI 420

Query: 421 PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDI 480
           PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDI
Sbjct: 421 PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDI 480

Query: 481 DANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKN 540
           DANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKN
Sbjct: 481 DANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKN 540

Query: 541 ALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELE 600
           ALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELE
Sbjct: 541 ALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELE 600

Query: 601 QVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD 641
           QVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD
Sbjct: 601 QVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD 641


>gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]
          Length = 641

 Score = 1261 bits (3263), Expect = 0.0
 Identities = 641/641 (100%), Positives = 641/641 (100%)

Query: 1   MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60
           MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
Sbjct: 1   MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60

Query: 61  LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEIS 120
           LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEIS
Sbjct: 61  LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEIS 120

Query: 121 SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA 180
           SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA
Sbjct: 121 SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA 180

Query: 181 IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH 240
           IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH
Sbjct: 181 IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH 240

Query: 241 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA 300
           FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA
Sbjct: 241 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA 300

Query: 301 RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN 360
           RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN
Sbjct: 301 RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN 360

Query: 361 KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI 420
           KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI
Sbjct: 361 KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI 420

Query: 421 PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDI 480
           PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDI
Sbjct: 421 PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDI 480

Query: 481 DANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKN 540
           DANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKN
Sbjct: 481 DANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKN 540

Query: 541 ALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELE 600
           ALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELE
Sbjct: 541 ALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELE 600

Query: 601 QVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD 641
           QVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD
Sbjct: 601 QVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD 641


>gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]
          Length = 641

 Score = 1130 bits (2922), Expect = 0.0
 Identities = 573/640 (89%), Positives = 606/640 (94%), Gaps = 2/640 (0%)

Query: 2   AKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAL 61
           AK  AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA+
Sbjct: 4   AKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 63

Query: 62  NPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISS 121
           NPQNTVFDAKRLIGRKF DPVVQ+DMK WPFQVIN+G KPKV VSYKGE KAFYPEEISS
Sbjct: 64  NPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEISS 123

Query: 122 MVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 181
           MVLTK+KE AEA+LG+PVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI
Sbjct: 124 MVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 183

Query: 182 AYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHF 241
           AYGLD+ G+GER+VLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV+HF
Sbjct: 184 AYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHF 243

Query: 242 VEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRAR 301
           VEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQA+LEIDSL+EGIDFYTSITRAR
Sbjct: 244 VEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRAR 303

Query: 302 FEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNK 361
           FEELC+DLFR TLEPVEKALRDAK+DKA+IHD+VLVGGSTRIPKVQ+LLQD+FNGRDLNK
Sbjct: 304 FEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDLNK 363

Query: 362 SINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIP 421
           SINPDEAVAYGAAVQAAILMGDKSE VQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIP
Sbjct: 364 SINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIP 423

Query: 422 TKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDID 481
           TKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRF+L+GIPPAPRGVPQIEVTFDID
Sbjct: 424 TKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTFDID 483

Query: 482 ANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNA 541
           ANGILNVTATDKSTGK NKITITNDKGRLSKEEIERMV +AEKYKAEDEVQRE+++AKNA
Sbjct: 484 ANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAAKNA 543

Query: 542 LESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQ 601
           LESYAFNMKS V DEGLKGKISE+DK K+LDKC E++SWL+ N LAEKDEF+HKRKELEQ
Sbjct: 544 LESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKELEQ 603

Query: 602 VCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD 641
           +CNPII+ LYQG G  GP   G     G   +GPTIEEVD
Sbjct: 604 MCNPIITKLYQG-GCTGP-ACGTGYVPGRPATGPTIEEVD 641


>gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]
          Length = 646

 Score = 1103 bits (2854), Expect = 0.0
 Identities = 553/646 (85%), Positives = 601/646 (93%), Gaps = 5/646 (0%)

Query: 1   MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60
           M+K  A+GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
Sbjct: 1   MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60

Query: 61  LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEIS 120
           +NP NTVFDAKRLIGR+F D VVQSDMKHWPF V+ND  +PKVQV YKGETK+FYPEE+S
Sbjct: 61  MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS 120

Query: 121 SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA 180
           SMVLTKMKEIAEAYLG  VTNAV+TVPAYFNDSQRQATKDAG IAGLNVLRIINEPTAAA
Sbjct: 121 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA 180

Query: 181 IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH 240
           IAYGLD+    ERNVLIFDLGGGTFDVSILTI+DGIFEVK+TAGDTHLGGEDFDNR+VNH
Sbjct: 181 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240

Query: 241 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA 300
           F+ EFKRKHKKDIS+NKRAVRRLRTACERAKRTLSSSTQAS+EIDSL+EGIDFYTSITRA
Sbjct: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA 300

Query: 301 RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN 360
           RFEEL +DLFR TL+PVEKALRDAKLDK+QIHD+VLVGGSTRIPK+QKLLQDFFNG++LN
Sbjct: 301 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN 360

Query: 361 KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI 420
           KSINPDEAVAYGAAVQAAIL GDKSENVQDLLLLDV PLSLG+ETAGGVMT LIKRN+TI
Sbjct: 361 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI 420

Query: 421 PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDI 480
           PTKQTQ FTTYSDNQPGVLIQVYEGERAMTKDNNLLG+FEL+GIPPAPRGVPQIEVTFDI
Sbjct: 421 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI 480

Query: 481 DANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKN 540
           DANGILNV+A DKSTGK NKITITNDKGRLSKE+IERMVQEAEKYKAEDE QR++VS+KN
Sbjct: 481 DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN 540

Query: 541 ALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELE 600
           +LESYAFNMK+ VEDE L+GKI++ DK+K+LDKC E+I+WLD N  AEK+EFEH++KELE
Sbjct: 541 SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE 600

Query: 601 QVCNPIISGLYQGAGG-PG--PGGF--GAQGPKGGSGSGPTIEEVD 641
           +VCNPII+ LYQ AGG PG  PGGF  G   P GG+ SGPTIEEVD
Sbjct: 601 KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 646


>gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]
          Length = 639

 Score = 1070 bits (2767), Expect = 0.0
 Identities = 537/642 (83%), Positives = 586/642 (91%), Gaps = 7/642 (1%)

Query: 2   AKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAL 61
           A+  AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA+
Sbjct: 3   ARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 62

Query: 62  NPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISS 121
           NP NT+FDAKRLIGRKF D  VQSDMKHWPF+V+++G KPKVQV YKGETK F+PEEISS
Sbjct: 63  NPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISS 122

Query: 122 MVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 181
           MVLTKMKEIAEAYLG  V +AVITVPAYFNDSQRQATKDAG I GLNVLRIINEPTAAAI
Sbjct: 123 MVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAI 182

Query: 182 AYGLDRTG--KGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVN 239
           AYGLD+ G   GE+NVLIFDLGGGTFDVSILTI+DGIFEVK+TAGDTHLGGEDFDNR+V+
Sbjct: 183 AYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVS 242

Query: 240 HFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITR 299
           H  EEFKRKHKKDI  NKRAVRRLRTACERAKRTLSSSTQAS+EIDSL+EG+DFYTSITR
Sbjct: 243 HLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITR 302

Query: 300 ARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDL 359
           ARFEEL +DLFR TLEPVEKALRDAKLDK QI ++VLVGGSTRIPK+QKLLQDFFNG++L
Sbjct: 303 ARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKEL 362

Query: 360 NKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNST 419
           NKSINPDEAVAYGAAVQAAIL+GDKSENVQDLLLLDV PLSLG+ETAGGVMT LIKRN+T
Sbjct: 363 NKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTT 422

Query: 420 IPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFD 479
           IPTKQTQ FTTYSDNQ  VL+QVYEGERAMTKDNNLLG+F+L+GIPPAPRGVPQIEVTFD
Sbjct: 423 IPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFD 482

Query: 480 IDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAK 539
           IDANGILNVTA DKSTGK NKITITNDKGRLSK++I+RMVQEAE+YK+EDE  R+RV+AK
Sbjct: 483 IDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAK 542

Query: 540 NALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKEL 599
           NALESY +N+K  VEDE L+GKISE DK K+LDKCQEVI+WLD N +AEKDE+EHK+KEL
Sbjct: 543 NALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKEL 602

Query: 600 EQVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD 641
           E+VCNPIIS LYQG  G G GG G+     G+  GPTIEEVD
Sbjct: 603 ERVCNPIISKLYQGGPGGGSGGGGS-----GASGGPTIEEVD 639


>gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]
          Length = 643

 Score = 1064 bits (2751), Expect = 0.0
 Identities = 525/636 (82%), Positives = 584/636 (91%)

Query: 6   AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQN 65
           A+GIDLGTTYSCVGVFQ G+VEI+ANDQGNRTTPSYVAFTDTERL+GDAAK+Q ALNP N
Sbjct: 8   AVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHN 67

Query: 66  TVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISSMVLT 125
           TVFDAKRLIGRKF D  VQSDMKHWPF+V+++G KPKV+V Y+GE K FYPEEISSMVL+
Sbjct: 68  TVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLS 127

Query: 126 KMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGL 185
           KMKE AEAYLG PV +AVITVPAYFNDSQRQATKDAG IAGLNVLRIINEPTAAAIAYGL
Sbjct: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187

Query: 186 DRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEEF 245
           DR G GERNVLIFDLGGGTFDVS+L+ID G+FEVKATAGDTHLGGEDFDNRLVNHF+EEF
Sbjct: 188 DRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNHFMEEF 247

Query: 246 KRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEEL 305
           +RKH KD+S NKRA+RRLRTACERAKRTLSSSTQA+LEIDSLFEG+DFYTSITRARFEEL
Sbjct: 248 RRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEEL 307

Query: 306 CSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINP 365
           CSDLFRSTLEPVEKALRDAKLDKAQIHD+VLVGGSTRIPKVQKLLQDFFNG++LNKSINP
Sbjct: 308 CSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSINP 367

Query: 366 DEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQT 425
           DEAVAYGAAVQAA+LMGDK E VQDLLLLDVAPLSLGLETAGGVMT LI+RN+TIPTKQT
Sbjct: 368 DEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQT 427

Query: 426 QIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGI 485
           Q FTTYSDNQPGV IQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGI
Sbjct: 428 QTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGI 487

Query: 486 LNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESY 545
           L+VTATD+STGKANKITITNDKGRLSKEE+ERMV EAE+YKAEDE QR+RV+AKN+LE++
Sbjct: 488 LSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAH 547

Query: 546 AFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQVCNP 605
            F++K ++++E L+ KI E D++K+ DKC+EV++WL+ N LAEK+E+EH+++ELEQ+C P
Sbjct: 548 VFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQICRP 607

Query: 606 IISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD 641
           I S LY G G PG    G Q  +G   +GP IEEVD
Sbjct: 608 IFSRLYGGPGVPGGSSCGTQARQGDPSTGPIIEEVD 643


>gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]
          Length = 493

 Score =  831 bits (2147), Expect = 0.0
 Identities = 416/473 (87%), Positives = 445/473 (94%), Gaps = 1/473 (0%)

Query: 1   MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60
           M+K  A+GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
Sbjct: 1   MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60

Query: 61  LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEIS 120
           +NP NTVFDAKRLIGR+F D VVQSDMKHWPF V+ND  +PKVQV YKGETK+FYPEE+S
Sbjct: 61  MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS 120

Query: 121 SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA 180
           SMVLTKMKEIAEAYLG  VTNAV+TVPAYFNDSQRQATKDAG IAGLNVLRIINEPTAAA
Sbjct: 121 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA 180

Query: 181 IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH 240
           IAYGLD+    ERNVLIFDLGGGTFDVSILTI+DGIFEVK+TAGDTHLGGEDFDNR+VNH
Sbjct: 181 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240

Query: 241 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA 300
           F+ EFKRKHKKDIS+NKRAVRRLRTACERAKRTLSSSTQAS+EIDSL+EGIDFYTSITRA
Sbjct: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA 300

Query: 301 RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN 360
           RFEEL +DLFR TL+PVEKALRDAKLDK+QIHD+VLVGGSTRIPK+QKLLQDFFNG++LN
Sbjct: 301 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN 360

Query: 361 KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI 420
           KSINPDEAVAYGAAVQAAIL GDKSENVQDLLLLDV PLSLG+ETAGGVMT LIKRN+TI
Sbjct: 361 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI 420

Query: 421 PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPA-PRGVP 472
           PTKQTQ FTTYSDNQPGVLIQVYEGERAMTKDNNLLG+FEL+G+P   P G P
Sbjct: 421 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFP 473



 Score = 38.9 bits (89), Expect = 0.015
 Identities = 21/37 (56%), Positives = 24/37 (64%), Gaps = 4/37 (10%)

Query: 609 GLYQGAGGPG--PGGF--GAQGPKGGSGSGPTIEEVD 641
           G ++  G PG  PGGF  G   P GG+ SGPTIEEVD
Sbjct: 457 GKFELTGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 493


>gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]
          Length = 654

 Score =  786 bits (2030), Expect = 0.0
 Identities = 398/618 (64%), Positives = 503/618 (81%), Gaps = 7/618 (1%)

Query: 7   IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVALNPQN 65
           +GIDLGTTYSCVGVF++G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP+N
Sbjct: 31  VGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPEN 90

Query: 66  TVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKG-ETKAFYPEEISSMVL 124
           TVFDAKRLIGR + DP VQ D+K  PF+V+    KP +QV   G +TK F PEEIS+MVL
Sbjct: 91  TVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVL 150

Query: 125 TKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYG 184
           TKMKE AEAYLG  VT+AV+TVPAYFND+QRQATKDAG IAGLNV+RIINEPTAAAIAYG
Sbjct: 151 TKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYG 210

Query: 185 LDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEE 244
           LD+  +GE+N+L+FDLGGGTFDVS+LTID+G+FEV AT GDTHLGGEDFD R++ HF++ 
Sbjct: 211 LDKR-EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKL 269

Query: 245 FKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEE 304
           +K+K  KD+ ++ RAV++LR   E+AKR LSS  QA +EI+S +EG DF  ++TRA+FEE
Sbjct: 270 YKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFEE 329

Query: 305 LCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSIN 364
           L  DLFRST++PV+K L D+ L K+ I ++VLVGGSTRIPK+Q+L+++FFNG++ ++ IN
Sbjct: 330 LNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGIN 389

Query: 365 PDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQ 424
           PDEAVAYGAAVQA +L GD  ++  DL+LLDV PL+LG+ET GGVMT LI RN+ +PTK+
Sbjct: 390 PDEAVAYGAAVQAGVLSGD--QDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKK 447

Query: 425 TQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANG 484
           +QIF+T SDNQP V I+VYEGER +TKDN+LLG F+L+GIPPAPRGVPQIEVTF+ID NG
Sbjct: 448 SQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNG 507

Query: 485 ILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALES 544
           IL VTA DK TG  NKITITND+ RL+ EEIERMV +AEK+  ED+  +ER+  +N LES
Sbjct: 508 ILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELES 567

Query: 545 YAFNMKSAVED-EGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQVC 603
           YA+++K+ + D E L GK+S  DK+ +    +E I WL+++  A+ ++F+ K+KELE++ 
Sbjct: 568 YAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIV 627

Query: 604 NPIISGLYQGAGGPGPGG 621
            PIIS LY G+ GP P G
Sbjct: 628 QPIISKLY-GSAGPPPTG 644


>gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]
          Length = 679

 Score =  567 bits (1462), Expect = e-162
 Identities = 315/633 (49%), Positives = 426/633 (67%), Gaps = 31/633 (4%)

Query: 3   KAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAL 61
           K A +GIDLGTT SCV V +  + +++ N +G RTTPS VAFT D ERL+G  AK Q   
Sbjct: 52  KGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVT 111

Query: 62  NPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVI--NDGDKPKVQVSYKGETKAFYPEEI 119
           NP NT +  KRLIGR++ DP VQ D+K+ PF+++  ++GD        +   K + P +I
Sbjct: 112 NPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGD-----AWVEAHGKLYSPSQI 166

Query: 120 SSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAA 179
            + VL KMKE AE YLG+   NAVITVPAYFNDSQRQATKDAG I+GLNVLR+INEPTAA
Sbjct: 167 GAFVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAA 226

Query: 180 AIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVN 239
           A+AYGLD++   ++ + ++DLGGGTFD+SIL I  G+FEVK+T GDT LGGEDFD  L+ 
Sbjct: 227 ALAYGLDKSE--DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLR 284

Query: 240 HFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGID----FYT 295
           H V+EFKR+   D++++  A++R+R A E+AK  LSSS Q  + +  L            
Sbjct: 285 HIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNM 344

Query: 296 SITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFN 355
            +TRA+FE + +DL R T+ P +KA++DA++ K+ I +++LVGG TR+PKVQ+ +QD F 
Sbjct: 345 KLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLF- 403

Query: 356 GRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIK 415
           GR  +K++NPDEAVA GAA+Q  +L GD    V D+LLLDV PLSLG+ET GGV T LI 
Sbjct: 404 GRAPSKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKLIN 459

Query: 416 RNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIE 475
           RN+TIPTK++Q+F+T +D Q  V I+V +GER M  DN LLG+F L GIPPAPRGVPQIE
Sbjct: 460 RNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIE 519

Query: 476 VTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRER 535
           VTFDIDANGI++V+A DK TG+  +I I    G LSK++IE MV+ AEKY  ED  ++ER
Sbjct: 520 VTFDIDANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIENMVKNAEKYAEEDRRKKER 578

Query: 536 VSAKNALESYAFNMKSAVEDEGLKGKISEADK-KKVLDKCQEVISWLDANTLAEKDEFEH 594
           V A N  E    + ++ +E+   +    E +K K+ + K +E+++  D+ T    +    
Sbjct: 579 VEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSET---GENIRQ 635

Query: 595 KRKELEQVCNPIISGLY-------QGAGGPGPG 620
               L+Q    +    Y       +G+G  G G
Sbjct: 636 AASSLQQASLKLFEMAYKKMASEREGSGSSGTG 668


>gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens]
          Length = 509

 Score =  316 bits (810), Expect = 4e-86
 Identities = 178/505 (35%), Positives = 286/505 (56%), Gaps = 7/505 (1%)

Query: 5   AAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQ 64
           AAIG+ LG T +CV V++ G+  ++AND G+R TP+ VA+++ E ++G AAK     N  
Sbjct: 2   AAIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNIS 61

Query: 65  NTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISSMVL 124
           NTV   K+++GR   DP  Q  +      VI    K + ++    ETK   PE+++ ++ 
Sbjct: 62  NTVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARLIF 121

Query: 125 TKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYG 184
           +KMKE A + LG    + VITVP  F + Q+ A  +A   AG NVLR+I+EP+AA +AYG
Sbjct: 122 SKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYG 181

Query: 185 LDRTGK-GERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVE 243
           + +    G+ N+L+F LGG +  +S++ ++ GI+ V +T  D ++GG  F   L  +   
Sbjct: 182 IGQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLAS 241

Query: 244 EFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFE 303
           EF+R  K D+  N RA+ +L  + E AK +LS+   A+  +DSL+EG DF  +++RARFE
Sbjct: 242 EFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFE 301

Query: 304 ELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSI 363
            LCS LF   +E +   L         I+ +VL GGS+RIPK+Q+L++D F   +L  SI
Sbjct: 302 LLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNSI 361

Query: 364 NPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAP---LSLGLETAGGV-MTALIKRNST 419
            PDE +  GAA++A IL+G ++  V+D L+++ +    L  G++ +G    T L    + 
Sbjct: 362 PPDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVLFPSGTP 421

Query: 420 IPTKQTQIFTTYSDNQPGVLIQVYEGE-RAMTKDNNLLGRFELSGIPPAPRGVPQIEVTF 478
           +P ++         +   V +++YE + +   K+     +  L  +     G+  I    
Sbjct: 422 LPARRQHTLQA-PGSISSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVL 480

Query: 479 DIDANGILNVTATDKSTGKANKITI 503
            +  +G L+VT TD+ TGK   I+I
Sbjct: 481 TMKRDGSLHVTCTDQETGKCEAISI 505


>gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]
          Length = 840

 Score =  294 bits (752), Expect = 2e-79
 Identities = 188/582 (32%), Positives = 309/582 (53%), Gaps = 27/582 (4%)

Query: 5   AAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQ 64
           + +GIDLG     V V + G +E IAN+  +R TP+ ++F    R IG AAK+QV  N +
Sbjct: 2   SVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAK 61

Query: 65  NTVFDAKRLIGRKFGDPVVQSDMKHWPFQVIN-DGDKPKVQVSYKGETKAFYPEEISSMV 123
           NTV   KR  GR F DP V+++  +  + ++        ++V+Y  E + F  E++++M+
Sbjct: 62  NTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAML 121

Query: 124 LTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAY 183
           L+K+KE AE+ L  PV + V++VP ++ D++R++  DA  IAGLN LR++NE TA A+AY
Sbjct: 122 LSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAY 181

Query: 184 G-----LDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV 238
           G     L    +  RNV+  D+G   + VS+   + G  +V ATA DT LGG  FD  LV
Sbjct: 182 GIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLV 241

Query: 239 NHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLS-SSTQASLEIDSLFEGIDFYTSI 297
           NHF EEF +K+K DI    RA+ RL   CE+ K+ +S +++   L I+     +D   ++
Sbjct: 242 NHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTM 301

Query: 298 TRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGR 357
            R +F E+C+DL      P+   L   KL K  I+ + +VGG+TRIP V++ +  FF G+
Sbjct: 302 NRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GK 360

Query: 358 DLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLE-----TAGGVMTA 412
           +L+ ++N DEAV  G A+Q AIL    +  V++  + DV P  + L        G     
Sbjct: 361 ELSTTLNADEAVTRGCALQCAIL--SPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCE 418

Query: 413 LIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRG-V 471
           +  +N   P  +     T+   +P  L   Y   + +   +  + +F +  + P   G  
Sbjct: 419 VFSKNHAAPFSKV---LTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSS 475

Query: 472 PQIEVTFDIDANGILNVTA---TDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAE 528
            +++V   ++ +GI +V++    +    + N+  +  D+   +KEE +  V + E +  E
Sbjct: 476 SKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEEEKMQVDQEEPHVEE 533

Query: 529 DEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKV 570
              Q+++  A+N  ES       A   +    +  +A K KV
Sbjct: 534 ---QQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKV 572



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 26/99 (26%), Positives = 50/99 (50%), Gaps = 2/99 (2%)

Query: 509 RLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKK 568
           ++ +E +   ++   K   +D++++ER  AKNA+E Y + M+  +  E  K  +SE D+ 
Sbjct: 588 QIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEK-FVSEDDRN 646

Query: 569 KVLDKCQEVISWL-DANTLAEKDEFEHKRKELEQVCNPI 606
               K ++  +WL +      K  +  K  EL+ +  PI
Sbjct: 647 SFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPI 685



 Score = 31.6 bits (70), Expect = 2.4
 Identities = 31/133 (23%), Positives = 49/133 (36%), Gaps = 21/133 (15%)

Query: 517 RMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQE 576
           R  +  E+ K  +E+ ++       ++ Y   + S    E     +  AD  KV     E
Sbjct: 688 RFQESEERPKLFEELGKQ-------IQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740

Query: 577 VISWLD------------ANTLAEKDEFEHKRKELEQVCNPIISGLYQGAGGPGPGGFGA 624
            + W++             + + +  E E K KEL   C+PIIS        P      A
Sbjct: 741 AMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNA 800

Query: 625 Q--GPKGGSGSGP 635
           +  GP  G G  P
Sbjct: 801 EQNGPVDGQGDNP 813


>gi|48928056 heat shock protein 70kDa family member 13 precursor
           [Homo sapiens]
          Length = 471

 Score =  278 bits (710), Expect = 1e-74
 Identities = 165/418 (39%), Positives = 243/418 (58%), Gaps = 50/418 (11%)

Query: 7   IGIDLGTTYSCVGVF--QHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQ 64
           IGIDLGTTY  VGVF    GKV++I ++ G+ + PS V+FTD +  +G  +      NPQ
Sbjct: 34  IGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQ 93

Query: 65  NTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISSMVL 124
           NT++DAKR IG+ F    +++++  +PF+V+N     +  V+   ET    PE + S +L
Sbjct: 94  NTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVT-SNETITVSPEYVGSRLL 152

Query: 125 TKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYG 184
            K+KE+AEAYLG PV NAVI+VPA F+  QR +T +A  +AGL +LR+INEPTAAA+AYG
Sbjct: 153 LKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYG 212

Query: 185 LDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEE 244
           L +      +VL+ DLGGGT DVS+L    G+F  +A +G+  LGG+DF+ RL+ +  ++
Sbjct: 213 LHKA--DVFHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQ 270

Query: 245 FKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEI-------------------- 284
             + +   +   K  + RLR A E  K  L+    A L +                    
Sbjct: 271 IYQTY-GFVPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELP 329

Query: 285 -DSLFEGID----------------------FYTSITRARFEELCSDLFRSTLEPVEKAL 321
            D L    D                      F T I+R  F+ L  DLF+  L P+++ L
Sbjct: 330 KDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVL 389

Query: 322 RDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAI 379
           ++  L+K +I ++VLVGGSTRIP++++++Q+FF G+D N S++PD AV  G A+QA I
Sbjct: 390 KEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFF-GKDPNTSVDPDLAVVTGVAIQAGI 446


>gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens]
          Length = 839

 Score =  275 bits (703), Expect = 9e-74
 Identities = 178/603 (29%), Positives = 313/603 (51%), Gaps = 42/603 (6%)

Query: 5   AAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQ 64
           + +GIDLG     + V + G +E IAN+  +R TP+ ++     R IG+AAK+Q+  N +
Sbjct: 2   SVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVR 61

Query: 65  NTVFDAKRLIGRKFGDPVVQSDMKHWPFQVIN-DGDKPKVQVSYKGETKAFYPEEISSMV 123
           NT+   K+L GR F DP+VQ++    P+++         V+V Y  E + F  E+++ M+
Sbjct: 62  NTIHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGML 121

Query: 124 LTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAY 183
           L K+KE +E  L  PV + VI++P++F D++R++   A  +AGLN LR++NE TA A+AY
Sbjct: 122 LAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAY 181

Query: 184 G-----LDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV 238
           G     L    +  RNV+  D+G   + V +   + G  +V AT  D +LGG +FD  LV
Sbjct: 182 GIYKQDLPPLDEKPRNVVFIDMGHSAYQVLVCAFNKGKLKVLATTFDPYLGGRNFDEALV 241

Query: 239 NHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLS-SSTQASLEIDSLFEGIDFYTSI 297
           ++F +EFK K+K ++ +N RA+ RL   CE+ K+ +S +++   L I+     +D  + +
Sbjct: 242 DYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKM 301

Query: 298 TRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGR 357
            RA+FE+LC+ L      P++  +  A L +  I  + +VGG+TRIP V++ +  FF  +
Sbjct: 302 NRAQFEQLCASLLARVEPPLKAVMEQANLQREDISSIEIVGGATRIPAVKEQITKFFL-K 360

Query: 358 DLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGL------ETAGGVMT 411
           D++ ++N DEAVA G A+Q AIL    +  V++  + D+ P S+ L      E   G   
Sbjct: 361 DISTTLNADEAVARGCALQCAIL--SPAFKVREFSITDLVPYSITLRWKTSFEDGSGECE 418

Query: 412 ALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRG- 470
              K +   P   +++  T+   +P  L   Y     +   +  +G F +  + P   G 
Sbjct: 419 VFCKNH---PAPFSKVI-TFHKKEPFELEAFYTNLHEVPYPDARIGSFTIQNVFPQSDGD 474

Query: 471 VPQIEVTFDIDANGILNVTAT--------DKSTGKANKITITNDKGRLSKEEIERMVQEA 522
             +++V   ++ +GI +V +         +     A   T T+ K   +K+ +++M  + 
Sbjct: 475 SSKVKVKVRVNIHGIFSVASASVIEKQNLEGDHSDAPMETETSFKNE-NKDNMDKMQVDQ 533

Query: 523 E--------KYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKC 574
           E        ++  E+E+       K+A+      +   ++    KGK+   D       C
Sbjct: 534 EEGHQKCHAEHTPEEEIDHTGAKTKSAVSDKQDRLNQTLK----KGKVKSIDLPIQSSLC 589

Query: 575 QEV 577
           +++
Sbjct: 590 RQL 592



 Score = 33.1 bits (74), Expect = 0.81
 Identities = 23/99 (23%), Positives = 49/99 (49%), Gaps = 2/99 (2%)

Query: 509 RLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKK 568
           +L ++ +   ++   K   +D++++ER  AKNA+E Y ++ +  +     K  I+  D  
Sbjct: 591 QLGQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDRLGTVYEK-FITPEDLS 649

Query: 569 KVLDKCQEVISWL-DANTLAEKDEFEHKRKELEQVCNPI 606
           K+    ++  +WL +      K  +  K +EL++   PI
Sbjct: 650 KLSAVLEDTENWLYEDGEDQPKQVYVDKLQELKKYGQPI 688


>gi|42544159 heat shock 105kD [Homo sapiens]
          Length = 858

 Score =  269 bits (687), Expect = 7e-72
 Identities = 182/551 (33%), Positives = 285/551 (51%), Gaps = 31/551 (5%)

Query: 5   AAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQ 64
           + +G+D+G+    + V + G +E IAN+  +R TPS ++F    R IG AAKNQ   +  
Sbjct: 2   SVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHAN 61

Query: 65  NTVFDAKRLIGRKFGDPVVQSDMKHWPFQVI---NDGDKPKVQVSYKGETKAFYPEEISS 121
           NTV + KR  GR F DP +Q + ++  + ++   N G    ++V Y GE   F  E+I++
Sbjct: 62  NTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGG--VGIKVMYMGEEHLFSVEQITA 119

Query: 122 MVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 181
           M+LTK+KE AE  L  PVT+ VI+VP++F D++R++  DA  I GLN LR++N+ TA A+
Sbjct: 120 MLLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVAL 179

Query: 182 AYG-----LDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNR 236
            YG     L    +  R V+  D+G   F VS    + G  +V  TA D  LGG++FD +
Sbjct: 180 NYGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEK 239

Query: 237 LVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSS-STQASLEIDSLFEGIDFYT 295
           LV HF  EFK K+K D     RA+ RL   CE+ K+ +SS ST   L I+      D   
Sbjct: 240 LVEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSG 299

Query: 296 SITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFN 355
            + R++FEELC++L +    P+   L    L    +  + +VGG+TRIP V++ +  FF 
Sbjct: 300 KMNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFF- 358

Query: 356 GRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGL------ETAGGV 409
           G+D++ ++N DEAVA G A+Q AIL    +  V++  + D  P  + L      E   GV
Sbjct: 359 GKDISTTLNADEAVARGCALQCAIL--SPAFKVREFSVTDAVPFPISLIWNHDSEDTEGV 416

Query: 410 MTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPR 469
              +  RN   P  +     T+    P  L   Y   + +      +GRF +  +     
Sbjct: 417 -HEVFSRNHAAPFSKV---LTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKD 472

Query: 470 G-VPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQE-AEKYKA 527
           G   +++V   ++ +GI  +     ST    +   T +    S+ ++E + Q   E    
Sbjct: 473 GEKSRVKVKVRVNTHGIFTI-----STASMVEKVPTEENEMSSEADMECLNQRPPENPDT 527

Query: 528 EDEVQRERVSA 538
           +  VQ++   A
Sbjct: 528 DKNVQQDNSEA 538



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 2/99 (2%)

Query: 509 RLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKK 568
           +L K+ +   ++   K   +D++++ER  AKNA+E Y +  +  +     K  I E D +
Sbjct: 605 QLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEK-FICEQDHQ 663

Query: 569 KVLDKCQEVISWL-DANTLAEKDEFEHKRKELEQVCNPI 606
             L    E   WL +      K  +  K +EL ++  P+
Sbjct: 664 NFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPV 702



 Score = 31.6 bits (70), Expect = 2.4
 Identities = 17/59 (28%), Positives = 26/59 (44%), Gaps = 12/59 (20%)

Query: 562 ISEADKKKVLDKCQEVISW------------LDANTLAEKDEFEHKRKELEQVCNPIIS 608
           I E++ KKV     EV+ W            LD + +    E + K KEL   C P+++
Sbjct: 743 IDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTKIKELNNTCEPVVT 801


>gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]
          Length = 999

 Score =  222 bits (565), Expect = 9e-58
 Identities = 157/525 (29%), Positives = 264/525 (50%), Gaps = 46/525 (8%)

Query: 5   AAIGIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNP 63
           A + +DLG+    V + + G  +EI+ N +  R TP  V   + ER  GD+A +    NP
Sbjct: 34  AVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNP 93

Query: 64  QNTVFDAKRLIGRKFGDPVVQSDMKHWP-FQVINDGDKPKVQVSYKGETKAFYPEEISSM 122
           + T+   + L+G++  +P V      +P  ++  D  +  V      + + F PEE+  M
Sbjct: 94  KATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQ-FSPEEVLGM 152

Query: 123 VLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIA 182
           VL   + +AE +   P+ +AVITVP +FN ++R+A   A  +AGL VL++IN+ TA A++
Sbjct: 153 VLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALS 212

Query: 183 YGLDRT---GKGERNVLIFDLGGGTFDVSILTI------DDGI---FEVKATAGDTHLGG 230
           YG+ R        +N++ +D+G G+   +I+T       + G+    +++    D  LGG
Sbjct: 213 YGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGG 272

Query: 231 EDFD----NRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDS 286
            + +     RL   F E+ K +  KD+ +N RA+ +L     R K  LS++     +I+ 
Sbjct: 273 LEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEG 332

Query: 287 LFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKV 346
           L + +DF   +TR  FEELC+DLF     PV++AL+ A++   +I  ++LVGG+TR+P+V
Sbjct: 333 LMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRV 392

Query: 347 QKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLD--VAPLSL--- 401
           Q++L       +L K+IN DEA A GA  QAA L   K+  V+  ++ D  V P+ +   
Sbjct: 393 QEVLLKAVGKEELGKNINADEAAAMGAVYQAAAL--SKAFKVKPFVVRDAVVYPILVEFT 450

Query: 402 -------GLETAGGVMTALIKRNSTIPTKQTQIFTTYSD------NQPGVLIQVYEGERA 448
                  G+ +       L  R    P ++   F  YS       N   +     E  R 
Sbjct: 451 REVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRV 510

Query: 449 MTKDNNLLGRFELSGIPPAPRGVPQ-----IEVTFDIDANGILNV 488
               N  L   +L G+  + +  P      I+  F++D +G+L++
Sbjct: 511 FGSQN--LTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSL 553



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 51/266 (19%), Positives = 102/266 (38%), Gaps = 45/266 (16%)

Query: 376 QAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQIFTTY---- 431
           ++ +L  D+ E+V + L+ D A     L   G  +++L    +T   K+    T      
Sbjct: 547 ESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEE 606

Query: 432 -----SDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRG--VPQIEVTFDID--- 481
                S ++PG  +++ E   A  +D +          PP P+G   P+ E   + +   
Sbjct: 607 SPAEGSKDEPGEQVELKEEAEAPVEDGS-------QPPPPEPKGDATPEGEKATEKENGD 659

Query: 482 --------------ANGILNVTATDKSTGKANKITITNDKG---------RLSKEEIERM 518
                           G+      +K    A K  +  + G          L ++++ + 
Sbjct: 660 KSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQS 719

Query: 519 VQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVI 578
           VQ+ +     D  ++ER  A N+LE++ F  +  +     +   +E  ++++  K     
Sbjct: 720 VQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAS 779

Query: 579 SWL-DANTLAEKDEFEHKRKELEQVC 603
           +WL D    A     + K  EL ++C
Sbjct: 780 TWLEDEGVGATTVMLKEKLAELRKLC 805


>gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]
          Length = 999

 Score =  222 bits (565), Expect = 9e-58
 Identities = 157/525 (29%), Positives = 264/525 (50%), Gaps = 46/525 (8%)

Query: 5   AAIGIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNP 63
           A + +DLG+    V + + G  +EI+ N +  R TP  V   + ER  GD+A +    NP
Sbjct: 34  AVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNP 93

Query: 64  QNTVFDAKRLIGRKFGDPVVQSDMKHWP-FQVINDGDKPKVQVSYKGETKAFYPEEISSM 122
           + T+   + L+G++  +P V      +P  ++  D  +  V      + + F PEE+  M
Sbjct: 94  KATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQ-FSPEEVLGM 152

Query: 123 VLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIA 182
           VL   + +AE +   P+ +AVITVP +FN ++R+A   A  +AGL VL++IN+ TA A++
Sbjct: 153 VLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALS 212

Query: 183 YGLDRT---GKGERNVLIFDLGGGTFDVSILTI------DDGI---FEVKATAGDTHLGG 230
           YG+ R        +N++ +D+G G+   +I+T       + G+    +++    D  LGG
Sbjct: 213 YGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGG 272

Query: 231 EDFD----NRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDS 286
            + +     RL   F E+ K +  KD+ +N RA+ +L     R K  LS++     +I+ 
Sbjct: 273 LEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEG 332

Query: 287 LFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKV 346
           L + +DF   +TR  FEELC+DLF     PV++AL+ A++   +I  ++LVGG+TR+P+V
Sbjct: 333 LMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRV 392

Query: 347 QKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLD--VAPLSL--- 401
           Q++L       +L K+IN DEA A GA  QAA L   K+  V+  ++ D  V P+ +   
Sbjct: 393 QEVLLKAVGKEELGKNINADEAAAMGAVYQAAAL--SKAFKVKPFVVRDAVVYPILVEFT 450

Query: 402 -------GLETAGGVMTALIKRNSTIPTKQTQIFTTYSD------NQPGVLIQVYEGERA 448
                  G+ +       L  R    P ++   F  YS       N   +     E  R 
Sbjct: 451 REVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRV 510

Query: 449 MTKDNNLLGRFELSGIPPAPRGVPQ-----IEVTFDIDANGILNV 488
               N  L   +L G+  + +  P      I+  F++D +G+L++
Sbjct: 511 FGSQN--LTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSL 553



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 51/266 (19%), Positives = 102/266 (38%), Gaps = 45/266 (16%)

Query: 376 QAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQIFTTY---- 431
           ++ +L  D+ E+V + L+ D A     L   G  +++L    +T   K+    T      
Sbjct: 547 ESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEE 606

Query: 432 -----SDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRG--VPQIEVTFDID--- 481
                S ++PG  +++ E   A  +D +          PP P+G   P+ E   + +   
Sbjct: 607 SPAEGSKDEPGEQVELKEEAEAPVEDGS-------QPPPPEPKGDATPEGEKATEKENGD 659

Query: 482 --------------ANGILNVTATDKSTGKANKITITNDKG---------RLSKEEIERM 518
                           G+      +K    A K  +  + G          L ++++ + 
Sbjct: 660 KSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQS 719

Query: 519 VQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVI 578
           VQ+ +     D  ++ER  A N+LE++ F  +  +     +   +E  ++++  K     
Sbjct: 720 VQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAS 779

Query: 579 SWL-DANTLAEKDEFEHKRKELEQVC 603
           +WL D    A     + K  EL ++C
Sbjct: 780 TWLEDEGVGATTVMLKEKLAELRKLC 805


>gi|38348298 ankyrin repeat domain 45 [Homo sapiens]
          Length = 266

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 2/95 (2%)

Query: 516 ERMVQEAEKYKAEDEVQ-RERVSAKNALESYAFNMKSAVED-EGLKGKISEADKKKVLDK 573
           ER    A +Y   + V+  +   A+  L+ Y   +  AV D E   GK+ + DK  +L  
Sbjct: 144 ERARDVAARYSQTECVEFLDWADARLTLKKYIAKVSLAVTDTEKGSGKLLKEDKNTILSA 203

Query: 574 CQEVISWLDANTLAEKDEFEHKRKELEQVCNPIIS 608
           C+    WL+ +T A  +E   +R++LE +  PI +
Sbjct: 204 CRAKNEWLETHTEASINELFEQRQQLEDIVTPIFT 238


>gi|9910266 kinesin family member 15 [Homo sapiens]
          Length = 1388

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 68/346 (19%), Positives = 144/346 (41%), Gaps = 31/346 (8%)

Query: 273  TLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIH 332
            +L +   + L+ D L E +     +    FE +  +L   T++    AL+ AKLD+ +  
Sbjct: 685  SLYTQNSSILDNDILNEPVP--PEMNEQAFEAISEEL--RTVQEQMSALQ-AKLDEEEHK 739

Query: 333  DLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLL 392
            +L L     ++      +Q+ F+   ++ +   +E ++    ++  +    +++   D L
Sbjct: 740  NLKLQQHVDKLEHHSTQMQELFSSERIDWTKQQEELLSQLNVLEKQL---QETQTKNDFL 796

Query: 393  LLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQV----YEGERA 448
              +V  L + L +A   ++++    S+  T Q + F   S+    V +Q+     E E+ 
Sbjct: 797  KSEVHDLRVVLHSADKELSSVKLEYSSFKTNQEKEFNKLSERHMHVQLQLDNLRLENEKL 856

Query: 449  MTKD-------NNL--LGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKAN 499
            +          +NL  + +FE+  +    +   +   T   D N ++ +   +K      
Sbjct: 857  LESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKL 916

Query: 500  KITITNDKGRLSKE---EIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDE 556
             +    DK   SKE    +E + QE +K  A+ E Q  +V            + S++E  
Sbjct: 917  SLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVISSLE-- 974

Query: 557  GLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQV 602
                K  ++DKK V D   + I  L  +   + +  +  ++EL+ +
Sbjct: 975  ----KSRDSDKKVVADLMNQ-IQELRTSVCEKTETIDTLKQELKDI 1015


>gi|31317303 heat shock 70kD protein 12B [Homo sapiens]
          Length = 686

 Score = 37.7 bits (86), Expect = 0.033
 Identities = 57/224 (25%), Positives = 91/224 (40%), Gaps = 40/224 (17%)

Query: 191 GERNVLIFDLGGGTFDVSILTIDD--GIFE--VKATAGDTHLGGED--FDNRLVNHFVEE 244
           G+R V + D GGGT D+++  ++   G  +   KA+ G     G D  F+  L   F E+
Sbjct: 313 GDRYV-VADCGGGTVDLTVHQLEQPHGTLKELYKASGGPYGAVGVDLAFEQLLCRIFGED 371

Query: 245 FKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFY---------T 295
           F    K+   Q   A   L  A E  KRT       +L I   F  IDFY         T
Sbjct: 372 FIATFKR---QRPAAWVDLTIAFEARKRTAGPHRAGALNISLPFSFIDFYRKQRGHNVET 428

Query: 296 SITRARFE--------------ELCSDLFRSTLEPVEKALRDAKLDKAQIHD---LVLVG 338
           ++ R+                 E  ++LF+ T+  + + + +A L + ++     L LVG
Sbjct: 429 ALRRSSVNFVKWSSQGMLRMSCEAMNELFQPTVSGIIQHI-EALLARPEVQGVKLLFLVG 487

Query: 339 GSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMG 382
           G      +Q  +Q     R L   +  D  +     ++ A+L G
Sbjct: 488 GFAESAVLQHAVQAALGARGLRVVVPHDVGL---TILKGAVLFG 528


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
           sapiens]
          Length = 1972

 Score = 37.0 bits (84), Expect = 0.056
 Identities = 25/100 (25%), Positives = 50/100 (50%), Gaps = 10/100 (10%)

Query: 503 ITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKI 562
           +T +K  L     E++  E E Y   +E++    + K  LE     M++ +E+E  +G+ 
Sbjct: 885 LTEEKNLLQ----EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQ 940

Query: 563 SEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQV 602
            +A++KK+  +       LD     E++E   ++ +LE+V
Sbjct: 941 LQAERKKMAQQ------MLDLEEQLEEEEAARQKLQLEKV 974


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
           sapiens]
          Length = 1979

 Score = 37.0 bits (84), Expect = 0.056
 Identities = 25/100 (25%), Positives = 50/100 (50%), Gaps = 10/100 (10%)

Query: 503 ITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKI 562
           +T +K  L     E++  E E Y   +E++    + K  LE     M++ +E+E  +G+ 
Sbjct: 892 LTEEKNLLQ----EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQ 947

Query: 563 SEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQV 602
            +A++KK+  +       LD     E++E   ++ +LE+V
Sbjct: 948 LQAERKKMAQQ------MLDLEEQLEEEEAARQKLQLEKV 981


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
           sapiens]
          Length = 1945

 Score = 37.0 bits (84), Expect = 0.056
 Identities = 25/100 (25%), Positives = 50/100 (50%), Gaps = 10/100 (10%)

Query: 503 ITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKI 562
           +T +K  L     E++  E E Y   +E++    + K  LE     M++ +E+E  +G+ 
Sbjct: 892 LTEEKNLLQ----EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQ 947

Query: 563 SEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQV 602
            +A++KK+  +       LD     E++E   ++ +LE+V
Sbjct: 948 LQAERKKMAQQ------MLDLEEQLEEEEAARQKLQLEKV 981


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
           sapiens]
          Length = 1938

 Score = 37.0 bits (84), Expect = 0.056
 Identities = 25/100 (25%), Positives = 50/100 (50%), Gaps = 10/100 (10%)

Query: 503 ITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKI 562
           +T +K  L     E++  E E Y   +E++    + K  LE     M++ +E+E  +G+ 
Sbjct: 885 LTEEKNLLQ----EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQ 940

Query: 563 SEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQV 602
            +A++KK+  +       LD     E++E   ++ +LE+V
Sbjct: 941 LQAERKKMAQQ------MLDLEEQLEEEEAARQKLQLEKV 974


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 37.0 bits (84), Expect = 0.056
 Identities = 35/131 (26%), Positives = 62/131 (47%), Gaps = 27/131 (20%)

Query: 494  STGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAK-----------NAL 542
            S+G        +  G++SKEE++    E +  K E+E ++ ++ A            + L
Sbjct: 956  SSGLKQNYDEMSPAGQISKEELQH---EFDLLKKENEQRKRKLQAALINRKELLQRVSRL 1012

Query: 543  ESYAFNMKSAVE-----DEGLKGKISEADKKK------VLDKCQEVISWLDANTLAEKD- 590
            E    N+K   +      E  +G++ E  + K      V  KCQE+  +L   T++EK+ 
Sbjct: 1013 EEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLK-QTISEKEV 1071

Query: 591  EFEHKRKELEQ 601
            E +H RK+LE+
Sbjct: 1072 ELQHIRKDLEE 1082


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 36.6 bits (83), Expect = 0.073
 Identities = 29/97 (29%), Positives = 50/97 (51%), Gaps = 7/97 (7%)

Query: 512 KEEIERMVQEAEKYKAEDEVQRERVSAKNA-LESYAFNMKSAVEDEGLKGKISEADKKKV 570
           K +++  +Q   +  AE E  R R++AK   LE    ++++ VE+E  + +  +A+KKK+
Sbjct: 882 KLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKM 941

Query: 571 LDKCQEVISWLDANTLA------EKDEFEHKRKELEQ 601
               QE+   L+    A      EK   E K K+LE+
Sbjct: 942 QQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEE 978


>gi|148839339 nexilin (F actin binding protein) [Homo sapiens]
          Length = 675

 Score = 36.6 bits (83), Expect = 0.073
 Identities = 23/77 (29%), Positives = 39/77 (50%)

Query: 486 LNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESY 545
           L++   D+   +A K +++  K +L+ EE+ER  QE  K +AE+E ++     K A E  
Sbjct: 225 LSLVMDDEIESEAKKESLSPGKLKLTFEELERQRQENRKKQAEEEARKRLEEEKRAFEEA 284

Query: 546 AFNMKSAVEDEGLKGKI 562
              M +  E+     KI
Sbjct: 285 RRQMVNEDEENQDTAKI 301



 Score = 34.7 bits (78), Expect = 0.28
 Identities = 32/109 (29%), Positives = 47/109 (43%), Gaps = 18/109 (16%)

Query: 507 KGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEG--------- 557
           K +LS EE+ER  +E EK KAE+E +R     K A      NM   V+D+          
Sbjct: 309 KLKLSFEEMERQRREDEKRKAEEEARRRIEEEKKAFAEARRNM--VVDDDSPEMYKTISQ 366

Query: 558 -------LKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKEL 599
                  L+    E  K+K+ ++ +            EK EFE  R+E+
Sbjct: 367 EFLTPGKLEINFEELLKQKMEEEKRRTEEERKHKLEMEKQEFEQLRQEM 415


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 36.2 bits (82), Expect = 0.096
 Identities = 25/92 (27%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 516 ERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQ 575
           E++  E E +   +E++    + K  LE    +++S VE+E  + +I + +KKK+    Q
Sbjct: 894 EQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQ 953

Query: 576 EVISWLDANTLA------EKDEFEHKRKELEQ 601
           ++   LD    A      EK   E K K++E+
Sbjct: 954 DLEEQLDEEEGARQKLQLEKVTAEAKIKKMEE 985


>gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo
           sapiens]
          Length = 482

 Score = 35.4 bits (80), Expect = 0.16
 Identities = 26/110 (23%), Positives = 53/110 (48%), Gaps = 3/110 (2%)

Query: 492 DKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKS 551
           +K   +  ++    D G   KEE E    E ++ + E  ++RER   +   E +    + 
Sbjct: 25  EKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERER---QRLHEEWLLREQK 81

Query: 552 AVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQ 601
           A E+  +K +  EA KK+  ++ +++    +     E++E E KR+E ++
Sbjct: 82  AQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKE 131


>gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens]
          Length = 282

 Score = 35.0 bits (79), Expect = 0.21
 Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 5/89 (5%)

Query: 513 EEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLD 572
           EE  R  +E  + KAEDE  R++ +  N +    +  K+  E +  K +     KKK+L 
Sbjct: 149 EERARREEEENRRKAEDEA-RKKKALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKILA 207

Query: 573 KCQEVISWLDANTLAEKDEFEHKRKELEQ 601
           + ++V++    N    +D+   K KEL Q
Sbjct: 208 ERRKVLAIDHLN----EDQLREKAKELWQ 232


>gi|130980075 centromere protein J [Homo sapiens]
          Length = 1338

 Score = 34.3 bits (77), Expect = 0.36
 Identities = 45/206 (21%), Positives = 86/206 (41%), Gaps = 19/206 (9%)

Query: 413  LIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVP 472
            ++   ST  T QT     Y +N+ G+L +  + + A  K    L +   S  PP      
Sbjct: 812  VLGNESTYGTPQT----CYPNNEIGILDKTIKRKIAPVKRGEDLSKSRRSRSPPTS---- 863

Query: 473  QIEVTFDIDANGILNVTATDKSTGKANKITITND-------KGRLSKEEIERMVQEAEKY 525
            ++ + F      +     +D   G   K+ I+ D       + ++ +E+I  +  E EK+
Sbjct: 864  ELMMKF---FPSLKPKPKSDSHLGNELKLNISQDQPPGDNARSQVLREKIIELETEIEKF 920

Query: 526  KAED-EVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDAN 584
            KAE+  + + R+  ++ALE     +    + +  +    E  KK+ + K Q+     +  
Sbjct: 921  KAENASLAKLRIERESALEKLRKEIADFEQQKAKELARIEEFKKEEMRKLQKERKVFEKY 980

Query: 585  TLAEKDEFEHKRKELEQVCNPIISGL 610
            T A +   + K +E  Q     I+ L
Sbjct: 981  TTAARTFPDKKEREEIQTLKQQIADL 1006


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.133    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,001,680
Number of Sequences: 37866
Number of extensions: 1047946
Number of successful extensions: 5674
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 88
Number of HSP's that attempted gapping in prelim test: 5241
Number of HSP's gapped (non-prelim): 438
length of query: 641
length of database: 18,247,518
effective HSP length: 109
effective length of query: 532
effective length of database: 14,120,124
effective search space: 7511905968
effective search space used: 7511905968
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.