Guide to the Human Genome
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Search of human proteins with 194239676

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194239676 crystallin, zeta isoform b [Homo sapiens]
         (295 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194239676 crystallin, zeta isoform b [Homo sapiens]                583   e-167
gi|194239674 crystallin, zeta isoform a [Homo sapiens]                566   e-162
gi|13236495 crystallin, zeta isoform a [Homo sapiens]                 566   e-162
gi|197927207 crystallin, zeta isoform c [Homo sapiens]                286   1e-77
gi|18379349 vesicle amine transport protein 1 [Homo sapiens]          130   1e-30
gi|24308257 vesicle amine transport protein 1 homolog (T. califo...   120   1e-27
gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]       90   3e-18
gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]       90   3e-18
gi|47519420 reticulon 4 interacting protein 1 precursor [Homo sa...    89   6e-18
gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a...    79   6e-15
gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b...    74   2e-13
gi|90669511 crystallin, zeta-like 1 [Homo sapiens]                     65   5e-11
gi|28557745 zinc binding alcohol dehydrogenase domain containing...    62   8e-10
gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]        60   2e-09
gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]        60   2e-09
gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]        60   2e-09
gi|41872631 fatty acid synthase [Homo sapiens]                         58   9e-09
gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo sa...    54   2e-07
gi|71743840 class IV alcohol dehydrogenase, mu or sigma subunit ...    51   1e-06
gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo sa...    51   1e-06
gi|156523966 class V alcohol dehydrogenase isoform 1 [Homo sapiens]    51   1e-06
gi|4501939 class V alcohol dehydrogenase isoform 2 [Homo sapiens]      51   1e-06
gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo s...    51   1e-06
gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo sa...    49   5e-06
gi|156627571 sorbitol dehydrogenase [Homo sapiens]                     48   1e-05
gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo sap...    41   0.001
gi|40807363 epidermal retinal dehydrogenase 2 [Homo sapiens]           31   1.1  
gi|109715829 short-chain dehydrogenase/reductase [Homo sapiens]        31   1.1  
gi|4557701 keratin 17 [Homo sapiens]                                   29   4.3  
gi|15277342 estradiol 17 beta-dehydrogenase 8 [Homo sapiens]           28   7.4  

>gi|194239676 crystallin, zeta isoform b [Homo sapiens]
          Length = 295

 Score =  583 bits (1504), Expect = e-167
 Identities = 295/295 (100%), Positives = 295/295 (100%)

Query: 1   MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS 60
           MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS
Sbjct: 1   MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS 60

Query: 61  RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK 120
           RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK
Sbjct: 61  RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK 120

Query: 121 LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTA 180
           LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTA
Sbjct: 121 LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTA 180

Query: 181 GTEEGQKIVLQNGAHEVFNHREVNYIDKIKVVGSRGTIEINPRDTMAKESSIIGVTLFSS 240
           GTEEGQKIVLQNGAHEVFNHREVNYIDKIKVVGSRGTIEINPRDTMAKESSIIGVTLFSS
Sbjct: 181 GTEEGQKIVLQNGAHEVFNHREVNYIDKIKVVGSRGTIEINPRDTMAKESSIIGVTLFSS 240

Query: 241 TKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMILLL 295
           TKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMILLL
Sbjct: 241 TKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMILLL 295


>gi|194239674 crystallin, zeta isoform a [Homo sapiens]
          Length = 329

 Score =  566 bits (1459), Expect = e-162
 Identities = 295/329 (89%), Positives = 295/329 (89%), Gaps = 34/329 (10%)

Query: 1   MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS 60
           MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS
Sbjct: 1   MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS 60

Query: 61  RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK 120
           RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK
Sbjct: 61  RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK 120

Query: 121 LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTA 180
           LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTA
Sbjct: 121 LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTA 180

Query: 181 GTEEGQKIVLQNGAHEVFNHREVNYIDKIK------------------------------ 210
           GTEEGQKIVLQNGAHEVFNHREVNYIDKIK                              
Sbjct: 181 GTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHG 240

Query: 211 ----VVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIG 266
               VVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIG
Sbjct: 241 GRVIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIG 300

Query: 267 SQYPLEKVAEAHENIIHGSGATGKMILLL 295
           SQYPLEKVAEAHENIIHGSGATGKMILLL
Sbjct: 301 SQYPLEKVAEAHENIIHGSGATGKMILLL 329


>gi|13236495 crystallin, zeta isoform a [Homo sapiens]
          Length = 329

 Score =  566 bits (1459), Expect = e-162
 Identities = 295/329 (89%), Positives = 295/329 (89%), Gaps = 34/329 (10%)

Query: 1   MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS 60
           MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS
Sbjct: 1   MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS 60

Query: 61  RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK 120
           RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK
Sbjct: 61  RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK 120

Query: 121 LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTA 180
           LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTA
Sbjct: 121 LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTA 180

Query: 181 GTEEGQKIVLQNGAHEVFNHREVNYIDKIK------------------------------ 210
           GTEEGQKIVLQNGAHEVFNHREVNYIDKIK                              
Sbjct: 181 GTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHG 240

Query: 211 ----VVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIG 266
               VVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIG
Sbjct: 241 GRVIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIG 300

Query: 267 SQYPLEKVAEAHENIIHGSGATGKMILLL 295
           SQYPLEKVAEAHENIIHGSGATGKMILLL
Sbjct: 301 SQYPLEKVAEAHENIIHGSGATGKMILLL 329


>gi|197927207 crystallin, zeta isoform c [Homo sapiens]
          Length = 192

 Score =  286 bits (732), Expect = 1e-77
 Identities = 154/190 (81%), Positives = 155/190 (81%), Gaps = 34/190 (17%)

Query: 140 LIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFN 199
           L+ SACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFN
Sbjct: 3   LLSSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFN 62

Query: 200 HREVNYIDKIK----------------------------------VVGSRGTIEINPRDT 225
           HREVNYIDKIK                                  VVGSRGTIEINPRDT
Sbjct: 63  HREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDT 122

Query: 226 MAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGS 285
           MAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGS
Sbjct: 123 MAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGS 182

Query: 286 GATGKMILLL 295
           GATGKMILLL
Sbjct: 183 GATGKMILLL 192


>gi|18379349 vesicle amine transport protein 1 [Homo sapiens]
          Length = 393

 Score =  130 bits (327), Expect = 1e-30
 Identities = 77/217 (35%), Positives = 119/217 (54%), Gaps = 4/217 (1%)

Query: 2   ATGQKLMRAVRVFEFGGPEVLKLRS-DIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS 60
           A    L+R + +  FGG + +KL+S   A P P   Q+ +++ ACG+N  +   R G Y 
Sbjct: 42  AASPPLLRCLVLTGFGGYDKVKLQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYD 101

Query: 61  RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK 120
           R P LP TPG + AGV+ AVG+  S  K GDRV   +  SG + E         + +PE 
Sbjct: 102 RLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLNR-SGMWQEEVTVPSVQTFLIPEA 160

Query: 121 LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAY-GLKILGT 179
           + F++ AA+ + Y TAY  L     ++ G SVLVH A+GGVG+AA Q+ R    + + GT
Sbjct: 161 MTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGT 220

Query: 180 AGTEEGQKIVLQNGAHEVFNHREVNYIDKIKVVGSRG 216
           A   +  + + +NG     ++   +Y+D+IK +  +G
Sbjct: 221 ASASK-HEALKENGVTHPIDYHTTDYVDEIKKISPKG 256


>gi|24308257 vesicle amine transport protein 1 homolog (T.
           californica)-like [Homo sapiens]
          Length = 419

 Score =  120 bits (301), Expect = 1e-27
 Identities = 71/210 (33%), Positives = 115/210 (54%), Gaps = 6/210 (2%)

Query: 8   MRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPY 67
           MRAV +  FGG   L+L    A+P P+D ++ I+V ACG+N ++  +R G     P  P 
Sbjct: 42  MRAVVLAGFGGLNKLRLFRK-AMPEPQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPL 100

Query: 68  TPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQGA 127
            PG + +G++EA+GD+   ++ GDRV      +  +AE        VYK+P+ + F + A
Sbjct: 101 VPGFECSGIVEALGDSVKGYEIGDRVMAFVNYN-AWAEVVCTPVEFVYKIPDDMSFSEAA 159

Query: 128 AIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAY-GLKILGTAGTEEGQ 186
           A  + + TAY  L   A ++ G SVLVH A GGVG A  Q+      + + GTA T + +
Sbjct: 160 AFPMNFVTAYVMLFEVANLREGMSVLVHSAGGGVGQAVAQLCSTVPNVTVFGTASTFKHE 219

Query: 187 KIVLQNGAHEVFNHREVNYIDKIKVVGSRG 216
            I  ++    +F+ R  +Y+ ++K + + G
Sbjct: 220 AI--KDSVTHLFD-RNADYVQEVKRISAEG 246


>gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]
          Length = 332

 Score = 89.7 bits (221), Expect = 3e-18
 Identities = 61/198 (30%), Positives = 98/198 (49%), Gaps = 1/198 (0%)

Query: 8   MRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPY 67
           M AV   + GGPE L ++ ++A P P + +VL+KV A  +N  +   R G Y   P    
Sbjct: 1   MLAVHFDKPGGPENLYVK-EVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASN 59

Query: 68  TPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQGA 127
             G + +G +  +G       K      +    GG A+Y    +  +  +PE L   Q A
Sbjct: 60  ILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAA 119

Query: 128 AIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQK 187
           AI   + TA++ L     V+AG+ VL+H    GVG AA Q+ R  G   L TAG+++  +
Sbjct: 120 AIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQ 179

Query: 188 IVLQNGAHEVFNHREVNY 205
           +  + GA   FN+++ ++
Sbjct: 180 MAEKLGAAAGFNYKKEDF 197


>gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]
          Length = 332

 Score = 89.7 bits (221), Expect = 3e-18
 Identities = 61/198 (30%), Positives = 98/198 (49%), Gaps = 1/198 (0%)

Query: 8   MRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPY 67
           M AV   + GGPE L ++ ++A P P + +VL+KV A  +N  +   R G Y   P    
Sbjct: 1   MLAVHFDKPGGPENLYVK-EVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASN 59

Query: 68  TPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQGA 127
             G + +G +  +G       K      +    GG A+Y    +  +  +PE L   Q A
Sbjct: 60  ILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAA 119

Query: 128 AIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQK 187
           AI   + TA++ L     V+AG+ VL+H    GVG AA Q+ R  G   L TAG+++  +
Sbjct: 120 AIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQ 179

Query: 188 IVLQNGAHEVFNHREVNY 205
           +  + GA   FN+++ ++
Sbjct: 180 MAEKLGAAAGFNYKKEDF 197


>gi|47519420 reticulon 4 interacting protein 1 precursor [Homo
           sapiens]
          Length = 396

 Score = 88.6 bits (218), Expect = 6e-18
 Identities = 89/354 (25%), Positives = 153/354 (43%), Gaps = 69/354 (19%)

Query: 7   LMRAVRVFEFGGPEVLKLRSDIAVPIPK-DHQVLIKVHACGVNPVETYIRSG------TY 59
           +M A  + ++G  EVL+   ++ +PI    ++V++KVHA  VNP++  +RSG        
Sbjct: 42  VMPAWVIDKYGKNEVLRFTQNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSGYGATALNM 101

Query: 60  SRKPL--------LPYTPGSDVAGVIEAVGDNASAFKKGDRVFTS--STISGGYAEYALA 109
            R PL         P T G DV+GV+   G +   FK GD V+ +      G  +E+ + 
Sbjct: 102 KRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQGTLSEFVVV 161

Query: 110 ADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVK----AGESVLVHGASGGVGLAA 165
           + + V   P+ L   Q A++     TA+ A+     +      G+ VL+ GASGGVG  A
Sbjct: 162 SGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFA 221

Query: 166 CQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKVV--------GSRGT 217
            Q+ +A+   +     +++  ++V + GA +V +++  +  +++K +           G+
Sbjct: 222 IQVMKAWDAHVTAVC-SQDASELVRKLGADDVIDYKSGSVEEQLKSLKPFDFILDNVGGS 280

Query: 218 IEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAA---LQAGMEIG-------W------- 260
            E    D + K S    VTL +       +   A   LQ G+ +G       W       
Sbjct: 281 TETWAPDFLKKWSGATYVTLVTPFLLNMDRLGIADGMLQTGVTVGSKALKHFWKGVHYRW 340

Query: 261 ---------------------LKPVIGSQYPLEKVAEAHENIIHGSGATGKMIL 293
                                ++PVI   +P  KV EA   +  G  A GK ++
Sbjct: 341 AFFMASGPCLDDIAELVDAGKIRPVIEQTFPFSKVPEAFLKVERGH-ARGKTVI 393


>gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a
           [Homo sapiens]
          Length = 373

 Score = 78.6 bits (192), Expect = 6e-15
 Identities = 46/170 (27%), Positives = 85/170 (50%)

Query: 8   MRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPY 67
           +RA+     G P  +    ++ +   +   V +K+ A  +NP +  +  G Y   P LP 
Sbjct: 43  VRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPA 102

Query: 68  TPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQGA 127
             G++    + AVG N +  K GD V  ++   G +   A+ ++  + ++P  +  +  A
Sbjct: 103 VGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAA 162

Query: 128 AIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKIL 177
            +G+   TAYR L+    ++ G+SV+ + ++ GVG A  QIA A GL+ +
Sbjct: 163 TLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTI 212


>gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b
           [Homo sapiens]
          Length = 297

 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 40/134 (29%), Positives = 70/134 (52%)

Query: 44  ACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGY 103
           A  +NP +  +  G Y   P LP   G++    + AVG N +  K GD V  ++   G +
Sbjct: 3   AAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLGTW 62

Query: 104 AEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGL 163
              A+ ++  + ++P  +  +  A +G+   TAYR L+    ++ G+SV+ + ++ GVG 
Sbjct: 63  RTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQ 122

Query: 164 AACQIARAYGLKIL 177
           A  QIA A GL+ +
Sbjct: 123 AVIQIAAALGLRTI 136


>gi|90669511 crystallin, zeta-like 1 [Homo sapiens]
          Length = 349

 Score = 65.5 bits (158), Expect = 5e-11
 Identities = 43/161 (26%), Positives = 78/161 (48%), Gaps = 5/161 (3%)

Query: 30  VPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASAFKK 89
           +P+ +D+ V ++V AC ++ + T + +    +K L P   G ++AG++  VG   S F+ 
Sbjct: 25  LPVTEDNFVKLQVKACALSQINTKLLAEMKMKKDLFPV--GREIAGIVLDVGSKVSFFQP 82

Query: 90  GDRVFTSSTISG---GYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACV 146
            D V     +     G  E     +H +   PEK+ + + A        AY AL + + +
Sbjct: 83  DDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTEAAGSIRDGVRAYTALHYLSHL 142

Query: 147 KAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQK 187
             G+SVL+   +   G  A Q+A   G K++ TA + E ++
Sbjct: 143 SPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLEDKQ 183


>gi|28557745 zinc binding alcohol dehydrogenase domain containing 2
           [Homo sapiens]
          Length = 377

 Score = 61.6 bits (148), Expect = 8e-10
 Identities = 49/184 (26%), Positives = 82/184 (44%), Gaps = 7/184 (3%)

Query: 20  EVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEA 79
           E + L  D  VP+P D  +L++    GVN  +    +G Y      P+  G +  G + A
Sbjct: 47  EAVTLSRDCPVPLPGDGDLLVRNRFVGVNASDINYSAGRYDPSVKPPFDIGFEGIGEVVA 106

Query: 80  VGDNASA-FKKGDRVFTSSTISGGYAEYALAADHTVYKLPE-KLDFKQGAAIGIPYFTAY 137
           +G +ASA +  G  V  +    G +AEY +        +P  K ++      G    TAY
Sbjct: 107 LGLSASARYTVGQAV--AYMAPGSFAEYTVVPASIATPVPSVKPEYLTLLVSGT---TAY 161

Query: 138 RALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEV 197
            +L     +  G+ VLV  A+GG G  A Q+++     ++GT  ++E    +   G    
Sbjct: 162 ISLKELGGLSEGKKVLVTAAAGGTGQFAMQLSKKAKCHVIGTCSSDEKSAFLKSLGCDRP 221

Query: 198 FNHR 201
            N++
Sbjct: 222 INYK 225


>gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]
          Length = 329

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 43/144 (29%), Positives = 72/144 (50%), Gaps = 12/144 (8%)

Query: 70  GSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKL----PEKLDFKQ 125
           G  VA V+E+      A  KG  V  S     G+  ++++    + KL    P+ +    
Sbjct: 65  GQQVAKVVESKN---VALPKGTIVLASP----GWTTHSISDGKDLEKLLTEWPDTIPLSL 117

Query: 126 G-AAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEE 184
               +G+P  TAY  L+    VK GE+V+V+ A+G VG    QIA+  G K++G  G++E
Sbjct: 118 ALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDE 177

Query: 185 GQKIVLQNGAHEVFNHREVNYIDK 208
               + + G   VFN++ V  +++
Sbjct: 178 KVAYLQKLGFDVVFNYKTVESLEE 201


>gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]
          Length = 329

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 43/144 (29%), Positives = 72/144 (50%), Gaps = 12/144 (8%)

Query: 70  GSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKL----PEKLDFKQ 125
           G  VA V+E+      A  KG  V  S     G+  ++++    + KL    P+ +    
Sbjct: 65  GQQVAKVVESKN---VALPKGTIVLASP----GWTTHSISDGKDLEKLLTEWPDTIPLSL 117

Query: 126 G-AAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEE 184
               +G+P  TAY  L+    VK GE+V+V+ A+G VG    QIA+  G K++G  G++E
Sbjct: 118 ALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDE 177

Query: 185 GQKIVLQNGAHEVFNHREVNYIDK 208
               + + G   VFN++ V  +++
Sbjct: 178 KVAYLQKLGFDVVFNYKTVESLEE 201


>gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]
          Length = 301

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 43/144 (29%), Positives = 72/144 (50%), Gaps = 12/144 (8%)

Query: 70  GSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKL----PEKLDFKQ 125
           G  VA V+E+      A  KG  V  S     G+  ++++    + KL    P+ +    
Sbjct: 65  GQQVAKVVESKN---VALPKGTIVLASP----GWTTHSISDGKDLEKLLTEWPDTIPLSL 117

Query: 126 G-AAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEE 184
               +G+P  TAY  L+    VK GE+V+V+ A+G VG    QIA+  G K++G  G++E
Sbjct: 118 ALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDE 177

Query: 185 GQKIVLQNGAHEVFNHREVNYIDK 208
               + + G   VFN++ V  +++
Sbjct: 178 KVAYLQKLGFDVVFNYKTVESLEE 201


>gi|41872631 fatty acid synthase [Homo sapiens]
          Length = 2511

 Score = 58.2 bits (139), Expect = 9e-09
 Identities = 29/83 (34%), Positives = 47/83 (56%)

Query: 102  GYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGV 161
            G A   L +   ++ +P     ++ A++ + Y TAY AL+    V+ GE++L+H  SGGV
Sbjct: 1621 GLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGV 1680

Query: 162  GLAACQIARAYGLKILGTAGTEE 184
            G AA  IA + G ++  T G+ E
Sbjct: 1681 GQAAIAIALSLGCRVFTTVGSAE 1703


>gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo
           sapiens]
          Length = 375

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 46/194 (23%), Positives = 78/194 (40%), Gaps = 50/194 (25%)

Query: 27  DIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASA 86
           ++ V  PK H+V IK+ A G+   + ++ SGT      LP   G + AG++E+VG+  + 
Sbjct: 26  EVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP--LPVILGHEAAGIVESVGEGVTT 83

Query: 87  FKKGDRVF----------------------------TSSTISGG---------------- 102
            K GD+V                                T+  G                
Sbjct: 84  VKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLG 143

Query: 103 ---YAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASG 159
              +++Y +  ++ V K+      ++   IG  + T Y + ++ A V  G +  V G  G
Sbjct: 144 ISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGL-G 202

Query: 160 GVGLAACQIARAYG 173
           GVGL+A    +A G
Sbjct: 203 GVGLSAIMGCKAAG 216


>gi|71743840 class IV alcohol dehydrogenase, mu or sigma subunit
           [Homo sapiens]
          Length = 386

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 49/223 (21%), Positives = 90/223 (40%), Gaps = 50/223 (22%)

Query: 27  DIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASA 86
           +I V  PK  +V IK+ A G+   + ++  GT   K   P   G +  G++E++G+  + 
Sbjct: 38  EIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK--FPVIVGHEATGIVESIGEGVTT 95

Query: 87  FKKGDRVF---------------------TSSTISG------------------------ 101
            K GD+V                        S I+G                        
Sbjct: 96  VKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNT 155

Query: 102 -GYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGG 160
             + EY +  + +V K+ +    ++   IG  + T Y A + +  VK G + +V G  GG
Sbjct: 156 STFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGL-GG 214

Query: 161 VGLAACQIARAYGL-KILGTAGTEEGQKIVLQNGAHEVFNHRE 202
           VGL+     ++ G  +I+G    ++  +  +  GA E  + ++
Sbjct: 215 VGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKD 257


>gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo
           sapiens]
          Length = 375

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 45/194 (23%), Positives = 76/194 (39%), Gaps = 50/194 (25%)

Query: 27  DIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASA 86
           D+ V  PK ++V IK+ A G+   + ++ SG       LP   G + AG++E+VG+  + 
Sbjct: 26  DVEVAPPKAYEVRIKMVAVGICHTDDHVVSGNLVTP--LPVILGHEAAGIVESVGEGVTT 83

Query: 87  FKKGDRVFTSSTISGG-------------------------------------------- 102
            K GD+V    T   G                                            
Sbjct: 84  VKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLG 143

Query: 103 ---YAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASG 159
              +++Y +  ++ V K+      ++   IG  + T Y + ++ A V  G +  V G  G
Sbjct: 144 TSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGL-G 202

Query: 160 GVGLAACQIARAYG 173
           GVGL+A    +A G
Sbjct: 203 GVGLSAVMGCKAAG 216


>gi|156523966 class V alcohol dehydrogenase isoform 1 [Homo sapiens]
          Length = 375

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 60/249 (24%), Positives = 103/249 (41%), Gaps = 53/249 (21%)

Query: 3   TGQKLM-RAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSR 61
           TGQ +  +A  +++ G P  ++   ++ V  PK  +V IKV A G+   E  +  G+   
Sbjct: 4   TGQVIRCKAAILWKPGAPFSIE---EVEVAPPKAKEVRIKVVATGLCGTEMKVL-GSKHL 59

Query: 62  KPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFT-------------------------- 95
             L P   G + AG++E++G+  S  K GD+V T                          
Sbjct: 60  DLLYPTILGHEGAGIVESIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQS 119

Query: 96  -SSTISGG-------------------YAEYALAADHTVYKLPEKLDFKQGAAIGIPYFT 135
            +  +S G                   + EY +  + +V K+      ++   I   + T
Sbjct: 120 KTQLMSDGTSRFTCKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFST 179

Query: 136 AYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYG-LKILGTAGTEEGQKIVLQNGA 194
            + A I++A V  G +  V G  GGVGL+     +A G  +I+G    +E  K   + GA
Sbjct: 180 GFGAAINTAKVTPGSTCAVFGL-GGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGA 238

Query: 195 HEVFNHREV 203
            E  N +++
Sbjct: 239 TECLNPQDL 247


>gi|4501939 class V alcohol dehydrogenase isoform 2 [Homo sapiens]
          Length = 368

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 60/249 (24%), Positives = 103/249 (41%), Gaps = 53/249 (21%)

Query: 3   TGQKLM-RAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSR 61
           TGQ +  +A  +++ G P  ++   ++ V  PK  +V IKV A G+   E  +  G+   
Sbjct: 4   TGQVIRCKAAILWKPGAPFSIE---EVEVAPPKAKEVRIKVVATGLCGTEMKVL-GSKHL 59

Query: 62  KPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFT-------------------------- 95
             L P   G + AG++E++G+  S  K GD+V T                          
Sbjct: 60  DLLYPTILGHEGAGIVESIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQS 119

Query: 96  -SSTISGG-------------------YAEYALAADHTVYKLPEKLDFKQGAAIGIPYFT 135
            +  +S G                   + EY +  + +V K+      ++   I   + T
Sbjct: 120 KTQLMSDGTSRFTCKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFST 179

Query: 136 AYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYG-LKILGTAGTEEGQKIVLQNGA 194
            + A I++A V  G +  V G  GGVGL+     +A G  +I+G    +E  K   + GA
Sbjct: 180 GFGAAINTAKVTPGSTCAVFGL-GGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGA 238

Query: 195 HEVFNHREV 203
            E  N +++
Sbjct: 239 TECLNPQDL 247


>gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo
           sapiens]
          Length = 374

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 61/244 (25%), Positives = 98/244 (40%), Gaps = 57/244 (23%)

Query: 9   RAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYT 68
           +A   +E G P  ++   +I V  PK H+V IK+ A  V   + Y  SG    +   P  
Sbjct: 9   KAAVAWEAGKPLSIE---EIEVAPPKAHEVRIKIIATAVCHTDAYTLSGA-DPEGCFPVI 64

Query: 69  PGSDVAGVIEAVGDNASAFKKGDRV----------------------------------- 93
            G + AG++E+VG+  +  K GD V                                   
Sbjct: 65  LGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKGLMP 124

Query: 94  -----FT--SSTI-----SGGYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALI 141
                FT    TI     +  ++EY + AD +V K+       +   +G    T Y A +
Sbjct: 125 DGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYGAAV 184

Query: 142 HSACVKAGESVLVHGASGGVGLA---ACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVF 198
           ++A ++ G    V G  GGVGLA    C++A A   +I+G    ++      + GA E  
Sbjct: 185 NTAKLEPGSVCAVFGL-GGVGLAVIMGCKVAGA--SRIIGVDINKDKFARAKEFGATECI 241

Query: 199 NHRE 202
           N ++
Sbjct: 242 NPQD 245


>gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo
           sapiens]
          Length = 375

 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 47/194 (24%), Positives = 77/194 (39%), Gaps = 50/194 (25%)

Query: 27  DIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASA 86
           ++ V  PK H+V IK+ A G+   + ++ SG       LP   G + AG++E+VG+  + 
Sbjct: 26  EVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP--LPVILGHEAAGIVESVGEGVTT 83

Query: 87  FKKGDRV---FTSS----------------------------------TISG-------- 101
            K GD+V   FT                                    T SG        
Sbjct: 84  VKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVG 143

Query: 102 --GYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASG 159
              +++Y +  ++ V K+      ++   IG  + T Y + +  A V  G +  V G  G
Sbjct: 144 VSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGL-G 202

Query: 160 GVGLAACQIARAYG 173
           GVGL+     +A G
Sbjct: 203 GVGLSVVMGCKAAG 216


>gi|156627571 sorbitol dehydrogenase [Homo sapiens]
          Length = 357

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 79/339 (23%), Positives = 127/339 (37%), Gaps = 81/339 (23%)

Query: 18  GPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVET----YIRSGTYSRKPLLPYTPGSDV 73
           GP  L+L +   +P P  ++VL+++H+ G+   +     Y R G +  K   P   G + 
Sbjct: 16  GPGDLRLEN-YPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKK--PMVLGHEA 72

Query: 74  AGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTV------------------- 114
           +G +E VG +    K GDRV           E+     + +                   
Sbjct: 73  SGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRF 132

Query: 115 --------YKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAAC 166
                   YKLP+ + F++GA I  P      A      V  G  VLV GA G +G+   
Sbjct: 133 YKHNAAFCYKLPDNVTFEEGALIE-PLSVGIHACRRGG-VTLGHKVLVCGA-GPIGMVTL 189

Query: 167 QIARAYG---LKILGTAGT------EEGQKIVLQ---NGAHEVFNHREVNYIDK----IK 210
            +A+A G   + +   + T      E G  +VLQ       E+    E     K    I+
Sbjct: 190 LVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIE 249

Query: 211 VVGSRGTIEINPRDTMA-----------------------KESSIIGVTLFSSTKEEFQQ 247
             G+  +I+     T +                       +E  I GV  + +T      
Sbjct: 250 CTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNT----WP 305

Query: 248 YAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGSG 286
            A ++ A   +  +KP++  ++PLEK  EA E    G G
Sbjct: 306 VAISMLASKSVN-VKPLVTHRFPLEKALEAFETFKKGLG 343


>gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo
           sapiens]
          Length = 380

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 52/248 (20%), Positives = 93/248 (37%), Gaps = 57/248 (22%)

Query: 9   RAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYT 68
           +A   +E G P  ++   ++ V  PK H+V I++ A  +   +  +    +      P  
Sbjct: 11  KAAIAWEAGKPLCIE---EVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAF-PVI 66

Query: 69  PGSDVAGVIEAVGDNASAFKKGDRVF---------------------------------- 94
            G + AG++E++G   +  K GD+V                                   
Sbjct: 67  VGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQ 126

Query: 95  ------TSSTISGGYAEY-----------ALAADHTVYKLPEKLDFKQGAAIGIPYFTAY 137
                 TS     G   Y            + +D  + K+ +  + ++   +G  + T Y
Sbjct: 127 QLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGY 186

Query: 138 RALIHSACVKAGESVLVHGASGGVGLAACQIARAYGL-KILGTAGTEEGQKIVLQNGAHE 196
            A I++A V  G +  V G  GGVGL+A    +A G  +I+G     E        GA +
Sbjct: 187 GAAINNAKVTPGSTCAVFGL-GGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATD 245

Query: 197 VFNHREVN 204
             N R+++
Sbjct: 246 CLNPRDLH 253


>gi|40807363 epidermal retinal dehydrogenase 2 [Homo sapiens]
          Length = 309

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 9/78 (11%)

Query: 129 IGIPYFTAYRALIHSACVK-----AGESVLVHGASGGVG-LAACQIARAYGLKIL---GT 179
           +G   F+   A+I +   K     AGE VL+ GA  G+G L A Q AR   + +L     
Sbjct: 15  LGKSLFSLLEAMIFALLPKPRKNVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINK 74

Query: 180 AGTEEGQKIVLQNGAHEV 197
            G EE  K+  + GA  V
Sbjct: 75  EGNEETCKMAREAGATRV 92


>gi|109715829 short-chain dehydrogenase/reductase [Homo sapiens]
          Length = 260

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 15/30 (50%), Positives = 19/30 (63%)

Query: 153 LVHGASGGVGLAACQIARAYGLKILGTAGT 182
           LV GASGG+G A  +     GLK++G A T
Sbjct: 15  LVTGASGGIGAAVARALVQQGLKVVGCART 44


>gi|4557701 keratin 17 [Homo sapiens]
          Length = 432

 Score = 29.3 bits (64), Expect = 4.3
 Identities = 29/125 (23%), Positives = 50/125 (40%), Gaps = 30/125 (24%)

Query: 131 IPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARA------------------- 171
           I  FT+  ++  S+ +  G S      SGG+G  +C++  A                   
Sbjct: 5   IRQFTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFG 64

Query: 172 ----YGLKILGTAG-TEEGQKIVLQNGAHEVFNHREVNYIDKIKVVGSRGT-IEINPRDT 225
               YG    G  G    G+K  +QN      N R  +Y+DK++ +    T +E+  RD 
Sbjct: 65  SGGGYGSSFGGVDGLLAGGEKATMQN-----LNDRLASYLDKVRALEEANTELEVKIRDW 119

Query: 226 MAKES 230
             +++
Sbjct: 120 YQRQA 124


>gi|15277342 estradiol 17 beta-dehydrogenase 8 [Homo sapiens]
          Length = 261

 Score = 28.5 bits (62), Expect = 7.4
 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 3/50 (6%)

Query: 139 ALIHSACVKAGESVLVHGASGGVGLAACQIARAYG---LKILGTAGTEEG 185
           AL+  A    G +V V  A  G  +AAC + RA     +++LG  G++EG
Sbjct: 14  ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEG 63


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,494,972
Number of Sequences: 37866
Number of extensions: 440095
Number of successful extensions: 820
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 772
Number of HSP's gapped (non-prelim): 45
length of query: 295
length of database: 18,247,518
effective HSP length: 102
effective length of query: 193
effective length of database: 14,385,186
effective search space: 2776340898
effective search space used: 2776340898
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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