Guide to the Human Genome
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Name: HSD17B8 Sequence: fasta or formatted (261aa) NCBI GI: 15277342
Description:

estradiol 17 beta-dehydrogenase 8

Referenced in:

Alcohol and Aldehyde Dehydrogenases
Steroid Hormones

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            13.0         34           3
 C cysteine            2.3          6           1
 D aspartate           4.6         12           2
 E glutamate           4.6         12           1
 F phenylalanine       2.7          7           1
 G glycine            11.1         29           2
 H histidine           1.5          4           1
 I isoleucine          5.0         13           2
 K lysine              3.1          8           1
 L leucine             8.0         21           2
 M methionine          2.3          6           1
 N asparagine          3.1          8           1
 P proline             3.8         10           2
 Q glutamine           5.0         13           1
 R arginine            5.4         14           1
 S serine              7.3         19           2
 T threonine           5.7         15           1
 V valine             10.3         27           3
 W tryptophan          0.4          1           1
 Y tyrosine            0.8          2           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   estradiol 17 beta-dehydrogenase 8 
CBR4                  0.214   carbonic reductase 4 
HSD17B10              0.204   hydroxysteroid (17-beta) dehydrogenase 10 isoform 1 [...
DHRS4                 0.175   peroxisomal short-chain alcohol dehydrogenase 
HSD17B10              0.173   hydroxysteroid (17-beta) dehydrogenase 10 isoform 2 ...
BDH2                  0.171   3-hydroxybutyrate dehydrogenase, type 2 
HSD17B4               0.159   hydroxysteroid (17-beta) dehydrogenase 4 
HSD17B14              0.155   dehydrogenase/reductase (SDR family) member 10 [Homo...
DCXR                  0.155   dicarbonyl/L-xylulose reductase 
DHRS2                 0.140   dehydrogenase/reductase member 2 isoform 2 
DHRS4L1               0.138   dehydrogenase/reductase (SDR family) member 4 like ...
PECR                  0.130   peroxisomal trans-2-enoyl-CoA reductase 
DECR1                 0.128   2,4-dienoyl CoA reductase 1 precursor 
HPGD                  0.126   hydroxyprostaglandin dehydrogenase 15-(NAD) isoform ...
DHRS11                0.107   short-chain dehydrogenase/reductase 
DECR2                 0.103   2,4-dienoyl CoA reductase 2 
DHRS2                 0.097   dehydrogenase/reductase member 2 isoform 1 
SDR16C5               0.093   epidermal retinal dehydrogenase 2 
RDH10                 0.087   retinol dehydrogenase 10 
HPGD                  0.082   hydroxyprostaglandin dehydrogenase 15-(NAD) isoform...
DHRS1                 0.082   dehydrogenase/reductase (SDR family) member 1 [Homo...
DHRS1                 0.082   dehydrogenase/reductase (SDR family) member 1 
HSD17B13              0.082   hydroxysteroid (17-beta) dehydrogenase 13 isoform A...
DHRS7B                0.080   dehydrogenase/reductase (SDR family) member 7B [Homo...
HSD17B11              0.078   estradiol 17-beta-dehydrogenase 11 
RDH16                 0.078   retinol dehydrogenase 16 
DHRS4L2               0.078   dehydrogenase/reductase (SDR family) member 4 like ...
SDR16C6               0.070   short chain dehydrogenase/reductase family 16C, mem...
RDH5                  0.070   retinol dehydrogenase 5 (11-cis and 9-cis) 
RDH14                 0.066   retinol dehydrogenase 14 (all-trans and 9-cis) [Homo...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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