Search of human proteins with 194097487

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194097487 RAN binding protein 3 isoform RANBP3-a [Homo
sapiens]
         (562 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194097487 RAN binding protein 3 isoform RANBP3-a [Homo sapiens]   1111   0.0  
gi|6466466 RAN binding protein 3 isoform RANBP3-d [Homo sapiens]     1105   0.0  
gi|194097489 RAN binding protein 3 isoform RANBP3-b [Homo sapiens]    910   0.0  
gi|239582743 RAN binding protein 3-like isoform 2 [Homo sapiens]      233   3e-61
gi|239582745 RAN binding protein 3-like isoform 1 [Homo sapiens]      231   2e-60
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    58   2e-08
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    57   6e-08
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        52   2e-06
gi|83267877 RANBP2-like and GRIP domain containing 5 isoform 1 [...    51   2e-06
gi|182765478 RANBP2-like and GRIP domain containing 6 [Homo sapi...    51   2e-06
gi|24308394 hypothetical protein LOC140893 [Homo sapiens]              51   2e-06
gi|169162953 PREDICTED: RANBP2-like and GRIP domain containing 8...    50   4e-06
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora...    50   7e-06
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo...    50   7e-06
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    50   7e-06
gi|211059431 RANBP2-like and GRIP domain containing 4 [Homo sapi...    49   9e-06
gi|221307607 RANBP2-like and GRIP domain containing 3 [Homo sapi...    49   1e-05
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             49   1e-05
gi|150418007 RAN binding protein 2 [Homo sapiens]                      49   1e-05
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     48   2e-05
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       48   2e-05
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   47   4e-05
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   47   4e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   47   4e-05
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    47   4e-05
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     47   5e-05
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    47   5e-05
gi|239747210 PREDICTED: hypothetical protein XP_002346689 [Homo ...    47   6e-05
gi|157266273 RANBP2-like and GRIP domain containing 1 [Homo sapi...    47   6e-05
gi|118200331 RANBP2-like and GRIP domain containing 2 [Homo sapi...    47   6e-05

>gi|194097487 RAN binding protein 3 isoform RANBP3-a [Homo sapiens]
          Length = 562

 Score = 1111 bits (2873), Expect = 0.0
 Identities = 562/562 (100%), Positives = 562/562 (100%)

Query: 1   MADLANEEKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGE 60
           MADLANEEKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGE
Sbjct: 1   MADLANEEKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGE 60

Query: 61  HALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVK 120
           HALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVK
Sbjct: 61  HALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVK 120

Query: 121 RERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAP 180
           RERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAP
Sbjct: 121 RERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAP 180

Query: 181 QPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEEKEPQKNESSNASE 240
           QPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEEKEPQKNESSNASE
Sbjct: 181 QPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEEKEPQKNESSNASE 240

Query: 241 EEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFLQYISS 300
           EEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFLQYISS
Sbjct: 241 EEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFLQYISS 300

Query: 301 SLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATPE 360
           SLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATPE
Sbjct: 301 SLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATPE 360

Query: 361 KESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGL 420
           KESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGL
Sbjct: 361 KESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGL 420

Query: 421 LRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDTEDQGV 480
           LRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDTEDQGV
Sbjct: 421 LRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDTEDQGV 480

Query: 481 KVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPGAAPSNEEDDSDDDDVL 540
           KVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPGAAPSNEEDDSDDDDVL
Sbjct: 481 KVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPGAAPSNEEDDSDDDDVL 540

Query: 541 APSGATAAGAGDEGDGQTTGST 562
           APSGATAAGAGDEGDGQTTGST
Sbjct: 541 APSGATAAGAGDEGDGQTTGST 562


>gi|6466466 RAN binding protein 3 isoform RANBP3-d [Homo sapiens]
          Length = 567

 Score = 1105 bits (2857), Expect = 0.0
 Identities = 562/567 (99%), Positives = 562/567 (99%), Gaps = 5/567 (0%)

Query: 1   MADLANEEKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGE 60
           MADLANEEKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGE
Sbjct: 1   MADLANEEKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGE 60

Query: 61  HALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVK 120
           HALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVK
Sbjct: 61  HALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVK 120

Query: 121 RERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAP 180
           RERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAP
Sbjct: 121 RERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAP 180

Query: 181 QPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADE-----EKEPQKNES 235
           QPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADE     EKEPQKNES
Sbjct: 181 QPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQKNES 240

Query: 236 SNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFL 295
           SNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFL
Sbjct: 241 SNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFL 300

Query: 296 QYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQ 355
           QYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQ
Sbjct: 301 QYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQ 360

Query: 356 EATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVE 415
           EATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVE
Sbjct: 361 EATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVE 420

Query: 416 RGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDT 475
           RGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDT
Sbjct: 421 RGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDT 480

Query: 476 EDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPGAAPSNEEDDSD 535
           EDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPGAAPSNEEDDSD
Sbjct: 481 EDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPGAAPSNEEDDSD 540

Query: 536 DDDVLAPSGATAAGAGDEGDGQTTGST 562
           DDDVLAPSGATAAGAGDEGDGQTTGST
Sbjct: 541 DDDVLAPSGATAAGAGDEGDGQTTGST 567


>gi|194097489 RAN binding protein 3 isoform RANBP3-b [Homo sapiens]
          Length = 499

 Score =  910 bits (2353), Expect = 0.0
 Identities = 468/473 (98%), Positives = 468/473 (98%), Gaps = 5/473 (1%)

Query: 95  RSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQA 154
           RSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQA
Sbjct: 27  RSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQA 86

Query: 155 PSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDT 214
           PSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDT
Sbjct: 87  PSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDT 146

Query: 215 AAWRSPSEAADE-----EKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLIN 269
           AAWRSPSEAADE     EKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLIN
Sbjct: 147 AAWRSPSEAADEVCALEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLIN 206

Query: 270 ESVDEADMENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSP 329
           ESVDEADMENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSP
Sbjct: 207 ESVDEADMENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSP 266

Query: 330 PKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITG 389
           PKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITG
Sbjct: 267 PKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITG 326

Query: 390 EEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLI 449
           EEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLI
Sbjct: 327 EEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLI 386

Query: 450 LNTKLWAQMQIDKASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSR 509
           LNTKLWAQMQIDKASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSR
Sbjct: 387 LNTKLWAQMQIDKASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSR 446

Query: 510 VEQEQEAKMPAPEPGAAPSNEEDDSDDDDVLAPSGATAAGAGDEGDGQTTGST 562
           VEQEQEAKMPAPEPGAAPSNEEDDSDDDDVLAPSGATAAGAGDEGDGQTTGST
Sbjct: 447 VEQEQEAKMPAPEPGAAPSNEEDDSDDDDVLAPSGATAAGAGDEGDGQTTGST 499


>gi|239582743 RAN binding protein 3-like isoform 2 [Homo sapiens]
          Length = 465

 Score =  233 bits (595), Expect = 3e-61
 Identities = 160/437 (36%), Positives = 225/437 (51%), Gaps = 75/437 (17%)

Query: 118 PVKRERTSSLT-QFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAV 176
           P KR R+SS T     SQS+            L+           Q P +  + V+RPA+
Sbjct: 69  PTKRVRSSSFTFHITDSQSQGVRKNNVFMTSALVQSSVDIKSA-EQGPVKHSKHVIRPAI 127

Query: 177 LQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEEKEPQKNESS 236
           LQ PQ ++ ++   + G   +                                       
Sbjct: 128 LQLPQARSCAKVRKTFGHKAL--------------------------------------- 148

Query: 237 NASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNY-FL 295
                E+C+ K+    +              I+E       EN          +TN  FL
Sbjct: 149 -----ESCKTKEKTNNK--------------ISEGNSYLLSENLSRARISVQLSTNQDFL 189

Query: 296 QYISSSLENSTN--SADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSES- 352
              S   + + +  S  + S+ FVFG+NM ERVL   KL +   +   ++ A E   +S 
Sbjct: 190 GATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQPQLE--NDSYAKEKPFKSI 247

Query: 353 --------SSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLF 404
                   SS+  + +  SL ESAAA++   +RKCLLEK++VITGEE E NVL++ CKLF
Sbjct: 248 PKFPVNFLSSRTDSIKNTSLIESAAAFSSQPSRKCLLEKIDVITGEETEHNVLKINCKLF 307

Query: 405 VFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKAS 464
           +F+KT+QSW+ERGRG LRLND ASTD GTLQSRL+MR QGSLRLILN+KLWAQM+I +A+
Sbjct: 308 IFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLWAQMKIQRAN 367

Query: 465 EKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPG 524
            K++RITA D ED  +K+FLI AS++DT  LYAA+HHR++AL+S  +Q    +  +    
Sbjct: 368 HKNVRITATDLEDYSIKIFLIQASAQDTAYLYAAIHHRLVALQSFNKQRDVNQAESLSET 427

Query: 525 AAPSN-EEDDSDDDDVL 540
           A   N E  D ++DD +
Sbjct: 428 AQQLNCESCDENEDDFI 444


>gi|239582745 RAN binding protein 3-like isoform 1 [Homo sapiens]
          Length = 490

 Score =  231 bits (588), Expect = 2e-60
 Identities = 126/243 (51%), Positives = 169/243 (69%), Gaps = 12/243 (4%)

Query: 308 SADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSES---------SSQEAT 358
           S  + S+ FVFG+NM ERVL   KL +   +   ++ A E   +S         SS+  +
Sbjct: 229 SFKSCSSNFVFGENMVERVLGTQKLTQPQLE--NDSYAKEKPFKSIPKFPVNFLSSRTDS 286

Query: 359 PEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGR 418
            +  SL ESAAA++   +RKCLLEK++VITGEE E NVL++ CKLF+F+KT+QSW+ERGR
Sbjct: 287 IKNTSLIESAAAFSSQPSRKCLLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGR 346

Query: 419 GLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDTEDQ 478
           G LRLND ASTD GTLQSRL+MR QGSLRLILN+KLWAQM+I +A+ K++RITA D ED 
Sbjct: 347 GTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLWAQMKIQRANHKNVRITATDLEDY 406

Query: 479 GVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPGAAPSN-EEDDSDDD 537
            +K+FLI AS++DT  LYAA+HHR++AL+S  +Q    +  +    A   N E  D ++D
Sbjct: 407 SIKIFLIQASAQDTAYLYAAIHHRLVALQSFNKQRDVNQAESLSETAQQLNCESCDENED 466

Query: 538 DVL 540
           D +
Sbjct: 467 DFI 469


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 80/387 (20%), Positives = 141/387 (36%), Gaps = 58/387 (14%)

Query: 23  KGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPPPAPE 82
           K  K+P ++   SDS  +   E E P           ++      P    A T  PP P 
Sbjct: 155 KAAKAPPKKAKSSDSDSDSSSEDEPP-----------KNQKPKITPVTVKAQTKAPPKPA 203

Query: 83  AQLPPFPR-ELAGRSAGGSSPEGGEDSDREDGNYCP-------------PVKRERT---- 124
              P     + A  S+  SS    +DS+ E     P             PVK   T    
Sbjct: 204 RAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRK 263

Query: 125 -SSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLP-----SQKPKE--QQRSVLRPAV 176
            SS       + EE+    + KP        PSA  P     +Q PK+  +++  +  + 
Sbjct: 264 SSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSE 323

Query: 177 LQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEEKEPQK--NE 234
             + +  + S+      T  V   A         + ++++  S S+++++++ P K    
Sbjct: 324 DSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGT 383

Query: 235 SSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAG------------- 281
           + N+S + A   K PA + A    Q +    KL+    D +  E                
Sbjct: 384 TKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVA 443

Query: 282 --HPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKL----NEV 335
              P A    A +   +       +S++ +D+SS++    +     V   P+        
Sbjct: 444 TTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAP 503

Query: 336 SSDANRENAAAESGSESSSQEATPEKE 362
           S  A+ +   AES + SSS +++ E+E
Sbjct: 504 SKPASAKKGKAESSNSSSSDDSSEEEE 530



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 57/261 (21%), Positives = 96/261 (36%), Gaps = 45/261 (17%)

Query: 10  PAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPA 69
           P  APP       +  K   E++   +S E+   E++          S+ E   +PP  A
Sbjct: 294 PPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESD----------SSSEEEKKPPTKA 343

Query: 70  GAS-ASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLT 128
             S A+T PPPA +A             A  SS     DS  +D     P    + SS  
Sbjct: 344 VVSKATTKPPPAKKA-------------AESSSDSSDSDSSEDDEAPSKPAGTTKNSSNK 390

Query: 129 QFPPSQSEERSSGFRLKPPT-----LIHGQAPSAG----------------LPSQKPKEQ 167
               ++S         K P      L+  +A S+                 + + KPK  
Sbjct: 391 PAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKAT 450

Query: 168 QRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEE 227
            ++ L     QAPQ    S +   S ++          AV       A   +PS+ A  +
Sbjct: 451 AKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAK 510

Query: 228 KEPQKNESSNASEEEACEKKD 248
           K   ++ +S++S++ + E+++
Sbjct: 511 KGKAESSNSSSSDDSSEEEEE 531



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 75/343 (21%), Positives = 130/343 (37%), Gaps = 60/343 (17%)

Query: 56  ESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNY 115
           E + E   E   P    A+ P   A    LPP   + A +++  SS E   D D E+   
Sbjct: 88  EDSSEEEEEVQGPPAKKAAVP---AKRVGLPP--GKAAAKASESSSSEESSDDDDEEDQK 142

Query: 116 CPPVKR--ERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLR 173
             PV++  +  +   + PP +++   S               S      +P + Q+  + 
Sbjct: 143 KQPVQKGVKPQAKAAKAPPKKAKSSDS--------------DSDSSSEDEPPKNQKPKIT 188

Query: 174 PAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEEKEPQKN 233
           P  ++A Q KA               P     A P  +   AA  S S ++    +  + 
Sbjct: 189 PVTVKA-QTKA---------------PPKPARAAPKIANGKAASSSSSSSSSSSSDDSEE 232

Query: 234 ESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINE--SVDEAD-----MENAGHPSAD 286
           E + A+ ++   KK     +A V       R    +E  S DE +     M+N   P + 
Sbjct: 233 EKAAATPKKTVPKKQ-VVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSS 291

Query: 287 TPTAT------NYFLQYISSSLENS--TNSADASSNKFVFGQNMSERVLSPPKLNEVSSD 338
            P  +      +   Q    ++E      S++ SS++     + SE    PP    VS  
Sbjct: 292 VPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDE---SDSSSEEEKKPPTKAVVSKA 348

Query: 339 ANR---ENAAAESGSESSSQEATPEKESLAESAAAYTKATARK 378
             +      AAES S+SS  +++ + E+ ++ A   TK ++ K
Sbjct: 349 TTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGT-TKNSSNK 390


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 57/229 (24%), Positives = 78/229 (34%), Gaps = 30/229 (13%)

Query: 10   PAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGH---PESAGEHALEPP 66
            PA +P  F        +  + +K+L  SG  P      PHH   H   P+    HA  P 
Sbjct: 963  PASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPH 1022

Query: 67   APAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGN------------ 114
             P   +  +P  P P   L P P  L G   GG SP  G  S    G+            
Sbjct: 1023 PPEMETGGSPDDPPPRLALGPQP-SLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPA 1081

Query: 115  ----YCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRS 170
                  PP    R +S   + P++S     G  +K   +        GLP         S
Sbjct: 1082 LRYFQLPP----RAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPAS 1137

Query: 171  VLRPAVLQAPQPK------ALSQTVPSSGTNGVSLPADCTGAVPAASPD 213
               P  + AP  K       +    PS+ ++G S     T A P   P+
Sbjct: 1138 PQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPE 1186



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 60/202 (29%), Positives = 76/202 (37%), Gaps = 29/202 (14%)

Query: 41   PRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGS 100
            P G A A         S G  A +PP    +     PPP P    P    E   R  G S
Sbjct: 1352 PLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGAS 1411

Query: 101  SPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKP------PTLIH-GQ 153
             P   + + RE G       +E+  SL   PP  +  RS   RL P      P L+  G 
Sbjct: 1412 PP---DPARRELGYRAGLGSQEK--SLPASPP--AARRSLLHRLPPTAPGVGPLLLQLGT 1464

Query: 154  APSAGLP-------SQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGA 206
             P A  P       S  P+E +R  L    L+  QP+A         T+G   P++    
Sbjct: 1465 EPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRA-------PVTSGRGPPSEDGPG 1517

Query: 207  VPAASPDTAAWRSP-SEAADEE 227
            VP  SP  +   SP S  A EE
Sbjct: 1518 VPPPSPRRSVPPSPTSPRASEE 1539



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 42/164 (25%), Positives = 55/164 (33%), Gaps = 17/164 (10%)

Query: 64   EPPAPAGASASTPPPPAPEA--QLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKR 121
            EPPAP    +      APE   +LP   R L       +    G     EDG   PP   
Sbjct: 1465 EPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPR-APVTSGRGPPSEDGPGVPPPSP 1523

Query: 122  ERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGL---------PSQKPKEQQRSVL 172
             R+      PPS +  R+S     P  ++   APS  +         P   P E   S  
Sbjct: 1524 RRS-----VPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFE 1578

Query: 173  RPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAA 216
            +P     P P       P+  T    +P     A P     TA+
Sbjct: 1579 KPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTAS 1622



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 24/101 (23%), Positives = 35/101 (34%), Gaps = 1/101 (0%)

Query: 5    ANEEKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALE 64
            A  EK +I  P  + +      S    +  S   E P         G G    +   A+ 
Sbjct: 1146 APSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMS 1205

Query: 65   PPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGG 105
            P  P+ +   TP  P+  A L  F  +      G +  EGG
Sbjct: 1206 PVPPSPSPVPTPASPSGPATL-DFTSQFGAALVGAARREGG 1245


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 91/379 (24%), Positives = 143/379 (37%), Gaps = 79/379 (20%)

Query: 24   GQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGA--SASTPPPPAP 81
            G  +P    N   S   P+  A A   G   P SA  HA  P   AG+  +A+  P    
Sbjct: 2313 GSGTPPTAANYPSSSRTPQAPASANLVG---PRSA--HATAPVNIAGSRTAAALAPASLT 2367

Query: 82   EAQLPPFPRELAGRSAGGSSPEGGEDS-DREDGNYCPPVKRERTSSLTQFPPSQSEERSS 140
             A++ P     A   A  +SP     + +R  G   PP+     S      PSQS  R +
Sbjct: 2368 SARMAP-----ALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQS--RMT 2420

Query: 141  GFRLKPPTLIHGQAPSAGL--PSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVS 198
              R   P+   GQAPS  L  P+Q   +Q RS + P+         ++QT P +G+  +S
Sbjct: 2421 SERAPSPSSRMGQAPSQSLLPPAQ---DQPRSPV-PSAFSDQSRCLIAQTTPVAGSQSLS 2476

Query: 199  LPA---------DCTGAVPAASP------------DTAAWRSPSEAADEEKEPQKNESSN 237
              A         D  G +   +P             T A +  + AA +  + +++ SS+
Sbjct: 2477 SGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSS 2536

Query: 238  ASEEEACEKKDPATQQAFVFGQNLRD---------------RVKLINESVDEADMENAGH 282
            +S   +      ++  +   G +  D               RV     +  EA  E  G 
Sbjct: 2537 SSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVRE--GR 2594

Query: 283  PSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRE 342
            P   TP          SSS  +S++S+ +SS+                     SS ++  
Sbjct: 2595 PPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSS--------------------SSSSSSS 2634

Query: 343  NAAAESGSESSSQEATPEK 361
            ++++ S S SSS   +P K
Sbjct: 2635 SSSSSSSSSSSSSSPSPAK 2653



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 50/172 (29%), Positives = 69/172 (40%), Gaps = 23/172 (13%)

Query: 21   KDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPPPA 80
            KDK + +P  Q   SDS  EP+  A AP        S        P+P G+S++   P  
Sbjct: 1605 KDKPRAAPRAQSG-SDSSPEPK--APAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEH 1661

Query: 81   PEAQLPPFPRELAGRSAGGSSPEGGEDS----DREDGNYCPPVKRE-RTSSLTQFPPSQS 135
            P       P+    R    SSPE    S     R      P + R+ R S  ++   S  
Sbjct: 1662 P-------PKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSP 1714

Query: 136  EERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQ 187
            E RS      PP   H ++PS   P  +P E+ RS  R     +P+ K  S+
Sbjct: 1715 ETRSR----TPPR--HRRSPSVSSP--EPAEKSRSSRRRRSASSPRTKTTSR 1758



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 64/294 (21%), Positives = 99/294 (33%), Gaps = 23/294 (7%)

Query: 95   RSAGGSSPEGGEDSD----REDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLI 150
            R   GSS E    S     R   N  P +K+ R SS      S    ++   RL     +
Sbjct: 721  RGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKS-RLSLRRSL 779

Query: 151  HGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVP-- 208
             G +P     SQ P  + RS        + QPKA S+T P    +  S P       P  
Sbjct: 780  SGSSPCPKQKSQTPPRRSRS-------GSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSR 832

Query: 209  ----AASPDTAAWRSPSEAADEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDR 264
                ++SP                 PQ NE S   +  +C +  P  +           R
Sbjct: 833  QSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPE----LKSRTPSR 888

Query: 265  VKLINESVDEADMENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSE 324
                  S            S    ++    ++ I S  + S + + + S   V  +    
Sbjct: 889  HSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPR 948

Query: 325  RVLS-PPKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATAR 377
            R  S  P  N  S    R + +  S  ++  +  TP ++S + S + Y K  A+
Sbjct: 949  RSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQ 1002



 Score = 36.6 bits (83), Expect = 0.063
 Identities = 59/265 (22%), Positives = 96/265 (36%), Gaps = 42/265 (15%)

Query: 21   KDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPP-- 78
            + K +   + +++LS S   P+ +++ P   +    S  +     P     S+S+PPP  
Sbjct: 766  RSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQ 825

Query: 79   --PAPEAQ----LPPFPRELAG---RSAGGSSPEGGEDSDREDGNYC-----PPVKRERT 124
                P  Q      P P+  +G   R    +SP+  E S       C      P  + RT
Sbjct: 826  KSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRT 885

Query: 125  SS------------LTQFPPSQSEERSSGFRLKPPTLIH-GQAPSAGLPSQKP-KEQQRS 170
             S             +  PP QS  RSS  + K   +I   Q   +G  S  P +   R+
Sbjct: 886  PSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRT 945

Query: 171  VLRPAVLQAPQPKALSQTVPSSGTNGVSLP-----------ADCTGAVPAASPDTAAWRS 219
              R +   +P     S+ +P    +G S P              +G++ +  P   A   
Sbjct: 946  TPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSI-SPYPKVKAQTP 1004

Query: 220  PSEAADEEKEPQKNESSNASEEEAC 244
            P  +    K P   E S  S  ++C
Sbjct: 1005 PGPSLSGSKSPCPQEKSKDSLVQSC 1029



 Score = 36.2 bits (82), Expect = 0.082
 Identities = 84/400 (21%), Positives = 148/400 (37%), Gaps = 48/400 (12%)

Query: 27   SPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPPPAPEAQLP 86
            S  + K  S +  + R +  +P     H ES    +    +P G  + +  P    A   
Sbjct: 1053 SSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRS 1112

Query: 87   PFPRELAGRSA-----GGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSG 141
            P  ++    SA      G SPE  +   + D +  P V        ++   ++S+E+ + 
Sbjct: 1113 PIRQDRGEFSASPMLKSGMSPE--QSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMA- 1169

Query: 142  FRLKPPTLIHGQAPSAGLPSQKPKEQQRSVL-RPAVLQAPQPKALSQTVPSSGTNGVSLP 200
                PP     +  +A  P QK K     V  RP      +    +     SG       
Sbjct: 1170 ---LPPQ----EDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPET 1222

Query: 201  ADCTGAVPAASPDTAAWRSPSEAADEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQN 260
             +   A+P +S D        E  ++ +EP     S+ S     E K+ +T   F     
Sbjct: 1223 KEQNSALPTSSQD----EELMEVVEKSEEPAGQILSHLSS----ELKEMSTSN-FESSPE 1273

Query: 261  LRDRVKL---INESVDEADMENAGHPSADTPTATNYFL---QYISSS--LENSTNSADAS 312
            + +R  +   +++S  +A +E    PS  +     +F    + +S+S   ENS  S    
Sbjct: 1274 VEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEF 1333

Query: 313  SNKFVFGQNMS-------ERVLSPPKLNEVSSDAN---RENAAAESGSESSSQEATPEKE 362
             N    G  M+       +  L+ P LN++ +D +   +E +   SG   SS E +P+  
Sbjct: 1334 RNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSG--HSSSELSPD-- 1389

Query: 363  SLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCK 402
               E A   +  +    +L+ V      E  S+    + K
Sbjct: 1390 -AVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMK 1428



 Score = 33.1 bits (74), Expect = 0.70
 Identities = 52/232 (22%), Positives = 74/232 (31%), Gaps = 42/232 (18%)

Query: 21  KDKGQKSPAEQKNLSDSGEEP------RGEAEAPHHGTG-----HPESAGEHALEPPAP- 68
           + + + + A+    + +G  P      RGE +AP    G      P S      +P +P 
Sbjct: 276 RSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPY 335

Query: 69  ------AGASASTPPPPAPEAQL----PPFPRELAGRSAGGSSPEGGEDSDREDGNYCPP 118
                     ++T P P+PE       PP P  L     GGS                 P
Sbjct: 336 EDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQ---------------P 380

Query: 119 VKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQ 178
           +    T+ L+Q P +   E S      PP        S+   S  P  Q   V R A   
Sbjct: 381 LA---TTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSS 437

Query: 179 APQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEEKEP 230
              PK      P S     S P     +   A  D +   +PS      + P
Sbjct: 438 PESPK--PAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSP 487



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 34/152 (22%), Positives = 51/152 (33%), Gaps = 15/152 (9%)

Query: 20   QKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPPP 79
            +K +   S +   + S S       + +    +    S+   +   P+PA       P P
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKP 2662

Query: 80   APEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYC-PPVKRERTSSLTQFPPSQSEER 138
            A   + PP  R          SP    DS R+  +    PV+R R S        QS   
Sbjct: 2663 ASPKKPPPGERR-------SRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSS 2715

Query: 139  SSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRS 170
              G R        GQ   +  PS K + +  S
Sbjct: 2716 ERGSR-------RGQRGDSRSPSHKRRRETPS 2740



 Score = 30.4 bits (67), Expect = 4.5
 Identities = 38/170 (22%), Positives = 66/170 (38%), Gaps = 20/170 (11%)

Query: 95   RSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQA 154
            RS+  SSPE       +DG    P +R R+ S     P   +   +  R        G  
Sbjct: 1418 RSSSASSPE------MKDGLPRTPSRRSRSGS----SPGLRDGSGTPSRHSLSGSSPGMK 1467

Query: 155  PSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDT 214
                 PS+   E   S    A+ Q P+P++ S + P      ++   + +G+  +    T
Sbjct: 1468 DIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKT 1527

Query: 215  AA-----WRSPSEAADE-----EKEPQKNESSNASEEEACEKKDPATQQA 254
             A      RS S ++ E        PQ+   S++S +   + + P  Q++
Sbjct: 1528 VARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRS 1577


>gi|83267877 RANBP2-like and GRIP domain containing 5 isoform 1 [Homo
            sapiens]
          Length = 1765

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 69/332 (20%), Positives = 123/332 (37%), Gaps = 60/332 (18%)

Query: 161  SQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSP 220
            SQ P    + +LRPA    P  K  S T   S   G S+P    G     S        P
Sbjct: 878  SQSPAYNSQYLLRPAANVTPT-KGSSNTEFKSTKEGFSIPVSADGFKFGIS-------EP 929

Query: 221  SEAADEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENA 280
                 + ++P +N++   +++ +  KK     +  +FGQ                     
Sbjct: 930  GNQEKKREKPLENDTGFQAQDISGRKKG----RGVIFGQ--------------------- 964

Query: 281  GHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDAN 340
                    T++ +    ++ S              F       E++ S    +     AN
Sbjct: 965  --------TSSTFTFADVAKSTSGEGFQFGKKDLNFKGFSGAGEKLFS----SRYGKMAN 1012

Query: 341  RENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQ 400
            + N + +   +  + +     +   E             + EKVE++TGEE E  +    
Sbjct: 1013 KANTSGDFEKDDDAYKTEDSDDIHFEPVVQ---------MPEKVELVTGEEGEKVLYSQG 1063

Query: 401  CKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQI 460
             KLF FD   + W ERG G L++  + +  +G L  R++MR +  L++  N  +   M +
Sbjct: 1064 VKLFRFDAEVRQWKERGLGNLKI--LKNEVNGKL--RMLMRREQVLKVCANHWITTTMNL 1119

Query: 461  D--KASEKSIRITAMDTEDQGVKVFLISASSK 490
                 S+++   +A D  D   K+  ++A  K
Sbjct: 1120 KPLSGSDRAWMWSASDFSDGDAKLERLAAKFK 1151



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 56/224 (25%), Positives = 96/224 (42%), Gaps = 36/224 (16%)

Query: 263  DRVKLINESVDEADMENAGH--PSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQ 320
            D   L  +++D++   ++ H  P A +P   N F        + ST  ++ S   F    
Sbjct: 1249 DNYDLREDALDDSVSSSSVHASPLASSPVRKNLF------RFDESTTGSNFS---FKSAL 1299

Query: 321  NMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCL 380
            ++S+   SP KLN+  +    +  +  +  E              E    Y +      L
Sbjct: 1300 SLSK---SPAKLNQSGTSVGTDEESVVTQEE--------------ERDGQYFEPVVP--L 1340

Query: 381  LEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVM 440
             + VEV +GEE E  V   + +++ +DK    W ERG G +++  + + D+   Q R+VM
Sbjct: 1341 PDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGDIKI--LQNYDN--KQVRIVM 1396

Query: 441  RTQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKV 482
            R    L+L  N ++   M +   K +E+    TA D  D   KV
Sbjct: 1397 RRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKV 1440


>gi|182765478 RANBP2-like and GRIP domain containing 6 [Homo sapiens]
          Length = 1765

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 69/332 (20%), Positives = 123/332 (37%), Gaps = 60/332 (18%)

Query: 161  SQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSP 220
            SQ P    + +LRPA    P  K  S T   S   G S+P    G     S        P
Sbjct: 878  SQSPAYNSQYLLRPAANVTPT-KGSSNTEFKSTKEGFSIPVSADGFKFGIS-------EP 929

Query: 221  SEAADEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENA 280
                 + ++P +N++   +++ +  KK     +  +FGQ                     
Sbjct: 930  GNQEKKREKPLENDTGFQAQDISGRKKG----RGVIFGQ--------------------- 964

Query: 281  GHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDAN 340
                    T++ +    ++ S              F       E++ S    +     AN
Sbjct: 965  --------TSSTFTFADVAKSTSGEGFQFGKKDLNFKGFSGAGEKLFS----SRYGKMAN 1012

Query: 341  RENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQ 400
            + N + +   +  + +     +   E             + EKVE++TGEE E  +    
Sbjct: 1013 KANTSGDFEKDDDAYKTEDSDDIHFEPVVQ---------MPEKVELVTGEEGEKVLYSQG 1063

Query: 401  CKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQI 460
             KLF FD   + W ERG G L++  + +  +G L  R++MR +  L++  N  +   M +
Sbjct: 1064 VKLFRFDAEVRQWKERGLGNLKI--LKNEVNGKL--RMLMRREQVLKVCANHWITTTMNL 1119

Query: 461  D--KASEKSIRITAMDTEDQGVKVFLISASSK 490
                 S+++   +A D  D   K+  ++A  K
Sbjct: 1120 KPLSGSDRAWMWSASDFSDGDAKLERLAAKFK 1151



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 56/224 (25%), Positives = 96/224 (42%), Gaps = 36/224 (16%)

Query: 263  DRVKLINESVDEADMENAGH--PSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQ 320
            D   L  +++D++   ++ H  P A +P   N F        + ST  ++ S   F    
Sbjct: 1249 DNYDLREDALDDSVSSSSVHASPLASSPVRKNLF------RFDESTTGSNFS---FKSAL 1299

Query: 321  NMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCL 380
            ++S+   SP KLN+  +    +  +  +  E              E    Y +      L
Sbjct: 1300 SLSK---SPAKLNQSGTSVGTDEESVVTQEE--------------ERDGQYFEPVVP--L 1340

Query: 381  LEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVM 440
             + VEV +GEE E  V   + +++ +DK    W ERG G +++  + + D+   Q R+VM
Sbjct: 1341 PDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGDIKI--LQNYDN--KQVRIVM 1396

Query: 441  RTQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKV 482
            R    L+L  N ++   M +   K +E+    TA D  D   KV
Sbjct: 1397 RRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKV 1440


>gi|24308394 hypothetical protein LOC140893 [Homo sapiens]
          Length = 664

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 47/194 (24%), Positives = 75/194 (38%), Gaps = 19/194 (9%)

Query: 51  GTGHPESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDR 110
           G   P+ AG+H     +PA A  ++P PP     L   P+ L+  + G   PE  E S  
Sbjct: 452 GQDTPKPAGQHG--SLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTP 509

Query: 111 EDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQ---KPKEQ 167
            D     P +    S L+   P  +E+  +G  L PP   H Q P    P      P+  
Sbjct: 510 MD-----PSRPLPGSQLSLSSPGSTEDEDTGRPLPPP---HPQPPPHPQPPDLDGHPEPS 561

Query: 168 QRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEE 227
           +  VLR      P+   L +T       G+S  A+ T +     P+    +   +    +
Sbjct: 562 KAEVLR------PESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRK 615

Query: 228 KEPQKNESSNASEE 241
           ++        AS++
Sbjct: 616 RKRASEPGDKASKK 629


>gi|169162953 PREDICTED: RANBP2-like and GRIP domain containing 8
            [Homo sapiens]
          Length = 1765

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 69/332 (20%), Positives = 122/332 (36%), Gaps = 60/332 (18%)

Query: 161  SQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSP 220
            SQ P    + +LRPA    P  K  S T   S   G S+P    G     S        P
Sbjct: 878  SQSPAYNSQYLLRPAANVTPT-KGSSNTEFKSTKEGFSIPVSADGFKFGIS-------EP 929

Query: 221  SEAADEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENA 280
                 + ++P +N++   +++    KK     +  +FGQ                     
Sbjct: 930  GNQEKKREKPLENDTGLQAQDIRGRKKG----RGVIFGQ--------------------- 964

Query: 281  GHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDAN 340
                    T++ +    ++ S              F       E++ S    +     AN
Sbjct: 965  --------TSSTFTFADVAKSTSGEGFQFGKKDLNFKGFSGAGEKLFS----SRYGKMAN 1012

Query: 341  RENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQ 400
            + N + +   +  + +     +   E             + EKVE++TGEE E  +    
Sbjct: 1013 KANTSGDFEKDDDAYKTEDSDDIHFEPVVQ---------MPEKVELVTGEEGEKVLYSQG 1063

Query: 401  CKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQI 460
             KLF FD   + W ERG G L++  + +  +G L  R++MR +  L++  N  +   M +
Sbjct: 1064 VKLFRFDAEVRQWKERGLGNLKI--LKNEVNGKL--RMLMRREQVLKVCANHWITTTMNL 1119

Query: 461  D--KASEKSIRITAMDTEDQGVKVFLISASSK 490
                 S+++   +A D  D   K+  ++A  K
Sbjct: 1120 KPLSGSDRAWMWSASDFSDGDAKLERLAAKFK 1151



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 56/224 (25%), Positives = 96/224 (42%), Gaps = 36/224 (16%)

Query: 263  DRVKLINESVDEADMENAGH--PSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQ 320
            D   L  +++D++   ++ H  P A +P   N F        + ST  ++ S   F    
Sbjct: 1249 DNYDLREDALDDSVSSSSVHASPLASSPVRKNLF------RFDESTTGSNFS---FKSAL 1299

Query: 321  NMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCL 380
            ++S+   SP KLN+  +    +  +  +  E              E    Y +      L
Sbjct: 1300 SLSK---SPAKLNQSGTSVGTDEESVVTQEE--------------ERDGQYFEPVVP--L 1340

Query: 381  LEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVM 440
             + VEV +GEE E  V   + +++ +DK    W ERG G +++  + + D+   Q R+VM
Sbjct: 1341 PDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGDIKI--LQNYDN--KQVRIVM 1396

Query: 441  RTQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKV 482
            R    L+L  N ++   M +   K +E+    TA D  D   KV
Sbjct: 1397 RRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKV 1440


>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 1 [Homo sapiens]
          Length = 559

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 70/317 (22%), Positives = 128/317 (40%), Gaps = 59/317 (18%)

Query: 48  PHHGTGHPESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGED 107
           P HG+   + A + + +   P   +      P  +++     +EL    A  S     +D
Sbjct: 177 PSHGS---KDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSS-----KD 228

Query: 108 SDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQ 167
           + R+ G    P K E+       PP ++  +     LK  T +   +P  G P   P   
Sbjct: 229 TSRKLGEGRLP-KEEKA------PPPKAAFKEPKMALKE-TKLESTSPKGGPPPPPPPPP 280

Query: 168 QRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEE 227
           + S  RPA   +P+P A  Q   SS           + + P  SP     R+ S ++  +
Sbjct: 281 RASSKRPATADSPKPSAKKQKKSSS---------KGSRSAPGTSP-----RTSSSSSFSD 326

Query: 228 KEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADT 287
           K+P K++SS   E+   E +    ++A    +         + S DEA  ++        
Sbjct: 327 KKPAKDKSSTRGEKVKAESEPREAKKALEVEE---------SNSEDEASFKS-------- 369

Query: 288 PTATNYFLQYISSSLENSTNSADASSNK-FVFGQNMSERVLSPPKLNEVSSDANRENAAA 346
                   +   SS  NS++S+D+SS+  F   QN S+  L     +  S +++ +++  
Sbjct: 370 --------ESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDS-- 419

Query: 347 ESGSESSSQEATPEKES 363
            S  E ++ +  P ++S
Sbjct: 420 -SSGEEAAGKTNPGRDS 435


>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
           sapiens]
          Length = 1158

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 60/248 (24%), Positives = 91/248 (36%), Gaps = 35/248 (14%)

Query: 8   EKPAIAPPVFVFQKDKGQKSPAEQ--KNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEP 65
           +KP   PP       K  K P E+  K      E+P    + P  G   P  A    LE 
Sbjct: 129 KKPKEKPP-------KATKKPKEKPPKATKKPKEKPPKATKKPPSGKRPPILAPSETLEW 181

Query: 66  PAPAGASASTPPPPAPEAQLPPF-----------PRELAGRSAGGSSPEGGEDSDREDGN 114
           P P       PP P PE +LP             P E     A    PE  E++++   +
Sbjct: 182 PLPP------PPSPGPE-ELPQEGGAPLSNNWQNPGEETHVEAREHQPEPEEETEQPTLD 234

Query: 115 YCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRP 174
           Y   ++RE      ++   Q + R    R + P  +  + P    P+  P+E+    ++P
Sbjct: 235 YNDQIEREDYEDF-EYIRRQKQPRPPPSRRRRPERVWPEPPEEKAPAPAPEERIEPPVKP 293

Query: 175 AVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEEKEPQKNE 234
            +   P        +P+             G  P   PD  A R   E  +E K+P+K +
Sbjct: 294 LLPPLPPDYGDGYVIPNYDDMDYYF-----GPPPPQKPD--AERQTDEEKEELKKPKKED 346

Query: 235 SSNASEEE 242
           SS   E +
Sbjct: 347 SSPKEETD 354



 Score = 29.6 bits (65), Expect = 7.7
 Identities = 44/218 (20%), Positives = 71/218 (32%), Gaps = 49/218 (22%)

Query: 38  GEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSA 97
           G+ P   AE P   T      G+    P  P  +   +P PP    + PP     A +  
Sbjct: 76  GKRPGTAAEVPPEKTKDKGKKGKKDKGPKVPKESLEGSPRPPKKGKEKPP----KATKKP 131

Query: 98  GGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSA 157
               P+  +    +     PP   + T    + PP  +++  SG R  PP L    APS 
Sbjct: 132 KEKPPKATKKPKEK-----PP---KATKKPKEKPPKATKKPPSGKR--PPIL----APSE 177

Query: 158 GLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAW 217
            L    P               P P    + +P  G                 +P +  W
Sbjct: 178 TLEWPLP---------------PPPSPGPEELPQEG----------------GAPLSNNW 206

Query: 218 RSPSEAADEEKEPQKNESSNASEEEACEKKDPATQQAF 255
           ++P E    E    + E    +E+   +  D   ++ +
Sbjct: 207 QNPGEETHVEAREHQPEPEEETEQPTLDYNDQIEREDY 244


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 45/160 (28%), Positives = 54/160 (33%), Gaps = 24/160 (15%)

Query: 14  PPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASA 73
           PP    +K +G   P + +     G++ R     P    G P   G     PP P G   
Sbjct: 182 PPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 241

Query: 74  STPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPS 133
             PP    + Q PP P +  G  A G S      S        PP K        Q PP 
Sbjct: 242 GPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARS--------PPGK-------PQGPPQ 286

Query: 134 QSEERSSGFRLKPPTLIHG-----QAPSAGLPSQKPKEQQ 168
           Q      G    PP    G     QAP AG P   P+  Q
Sbjct: 287 QEGNNPQG----PPPPAGGNPQQPQAPPAGQPQGPPRPPQ 322



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 52/218 (23%), Positives = 67/218 (30%), Gaps = 23/218 (10%)

Query: 14  PPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASA 73
           PP     + +G   P + +     G++ R     P    G P   G     PP P G   
Sbjct: 121 PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 180

Query: 74  STPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPS 133
             PP    + Q PP P +       G  P+G    D+   +  PP K        Q PP 
Sbjct: 181 GPPPQGGKKPQGPPPPGK-----PQGPPPQG----DKSRSSQSPPGK-------PQGPPP 224

Query: 134 QSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSG 193
           Q   +  G    PP    G  P  G   Q P    +    PA   +    A S      G
Sbjct: 225 QGGNQPQG-PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQG 283

Query: 194 TNGVSLPADCTGAVPAASPDTAAWRSPSEAADEEKEPQ 231
                 P    G  P   P  A        A    +PQ
Sbjct: 284 ------PPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQ 315



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 44/170 (25%), Positives = 54/170 (31%), Gaps = 24/170 (14%)

Query: 14  PPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASA 73
           PP     K +G   P + +     G++ R     P    G P   G     PP P G   
Sbjct: 60  PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 119

Query: 74  STPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPS 133
             PP      Q PP P +       G  P+G    D+      PP K        Q PP 
Sbjct: 120 GPPPQGGNRPQGPPPPGK-----PQGPPPQG----DKSRSPRSPPGK-------PQGPPP 163

Query: 134 QSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPK 183
           Q   +  G    PP    G  P  G   Q P         P   Q P P+
Sbjct: 164 QGGNQPQG-PPPPPGKPQGPPPQGGKKPQGPPP-------PGKPQGPPPQ 205



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 55/230 (23%), Positives = 75/230 (32%), Gaps = 39/230 (16%)

Query: 3   DLANEEKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHA 62
           D++ EE P++             + P+ Q      G +P+G    P    G P   G   
Sbjct: 22  DVSQEESPSLIAG--------NPQGPSPQ-----GGNKPQGPPPPPGKPQGPPPQGGNKP 68

Query: 63  LEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRE 122
             PP P       P  P P+      PR   G+   G  P+GG   ++  G   PP K  
Sbjct: 69  QGPPPP-----GKPQGPPPQGDKSRSPRSPPGKPQ-GPPPQGG---NQPQGPPPPPGK-- 117

Query: 123 RTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQP 182
                 Q PP Q   R  G    PP       P  G  S+ P+        P   Q P P
Sbjct: 118 -----PQGPPPQGGNRPQG---PPPPGKPQGPPPQGDKSRSPRSP------PGKPQGPPP 163

Query: 183 KALSQTV-PSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEEKEPQ 231
           +  +Q   P         P    G  P   P     + P    D+ +  Q
Sbjct: 164 QGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQ 213



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 26/86 (30%), Positives = 35/86 (40%), Gaps = 11/86 (12%)

Query: 9   KPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAP-----HHGTGHPESAGEHAL 63
           KP   PP       K Q  PA+  + S S   P G+ + P     ++  G P  AG +  
Sbjct: 250 KPQGPPP-----PGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQ 304

Query: 64  EPPAPAGASASTPPPPAPEAQLPPFP 89
           +P AP       PP P P+   P  P
Sbjct: 305 QPQAPPAGQPQGPPRP-PQGGRPSRP 329


>gi|211059431 RANBP2-like and GRIP domain containing 4 [Homo sapiens]
          Length = 1758

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 67/332 (20%), Positives = 123/332 (37%), Gaps = 60/332 (18%)

Query: 161  SQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSP 220
            SQ P    + +LRPA    P  K  S T   S   G S+P    G     S        P
Sbjct: 879  SQSPAYNSQYLLRPAANVTPT-KGSSNTEFKSTKEGFSIPVSADGFKFGIS-------EP 930

Query: 221  SEAADEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENA 280
                 E ++P +N++   +++ + +K      +  +FGQ                     
Sbjct: 931  GNQEKESEKPLENDTGFQAQDISGQKNG----RGVIFGQ--------------------- 965

Query: 281  GHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDAN 340
                    T++ +    ++ S              F       E++ S    ++    AN
Sbjct: 966  --------TSSTFTFADVAKSTSGEGFQFGKKDPNFKGFSGAGEKLFS----SQCGKMAN 1013

Query: 341  RENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQ 400
            + N + +   +  + +     +   E             + EKVE++ GEE E  +    
Sbjct: 1014 KANTSGDFEKDDDAYKTEDSDDIHFEPVVQ---------MPEKVELVIGEEGEKVLYSQG 1064

Query: 401  CKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQI 460
             KLF FD   + W ERG G L++  + +  +G  + R++MR +  L++  N  +   M +
Sbjct: 1065 VKLFRFDAEVRQWKERGLGNLKI--LKNEVNG--KPRMLMRREQVLKVCANHWITTTMNL 1120

Query: 461  D--KASEKSIRITAMDTEDQGVKVFLISASSK 490
                 S+++   +A D  D   K+  ++A  K
Sbjct: 1121 KPLSGSDRAWMWSASDFSDGDAKLERLAAKFK 1152



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 63/258 (24%), Positives = 107/258 (41%), Gaps = 36/258 (13%)

Query: 227  EKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSAD 286
            E+E + + +  A   +   K +P      +   N   R   +++SV  + +  +  P A 
Sbjct: 1218 EEENKGSGTGAAGASDTTIKPNPENTGPTLEWDNCDLREDALDDSVSSSSVHAS--PLAS 1275

Query: 287  TPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAA 346
            +P   N F    S++  N +  +  S +K            SP KLN+  +         
Sbjct: 1276 SPVRKNLFHFGESTTGSNFSFKSALSPSK------------SPAKLNQSGTSV------- 1316

Query: 347  ESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVF 406
              G++  S + T E+E   +             L + VEV +GEE E  V   + +L+ +
Sbjct: 1317 --GTDEES-DVTQEEERDGQYFEPVVP------LPDLVEVSSGEENEKVVFSHRAELYRY 1367

Query: 407  DKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQID--KAS 464
            DK    W ERG G +++  + + D+   Q R+VMR    L+L  N  +   M +   K +
Sbjct: 1368 DKDVGQWKERGIGDIKI--LQNYDN--KQVRIVMRRDQVLKLCANHTITPDMSLQNMKGT 1423

Query: 465  EKSIRITAMDTEDQGVKV 482
            E+    TA D  D   KV
Sbjct: 1424 ERVWVWTACDFADGERKV 1441



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 21/84 (25%), Positives = 36/84 (42%)

Query: 300  SSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATP 359
            SS   +T  A  S  KFVFG    +R+ S  K    +   +    +    S ++S ++  
Sbjct: 1523 SSTSETTTKAVVSPPKFVFGSESVKRIFSSEKSKPFAFGNSSATGSLFGFSFNASLKSNN 1582

Query: 360  EKESLAESAAAYTKATARKCLLEK 383
             + S    + + +K   +KC L K
Sbjct: 1583 SETSSVAQSGSESKVEPKKCELSK 1606


>gi|221307607 RANBP2-like and GRIP domain containing 3 [Homo sapiens]
          Length = 1758

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 67/332 (20%), Positives = 123/332 (37%), Gaps = 60/332 (18%)

Query: 161  SQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSP 220
            SQ P    + +LRPA    P  K  S T   S   G S+P    G     S        P
Sbjct: 879  SQSPAYNSQYLLRPAANVTPT-KGSSNTEFKSTKEGFSIPVSADGFKFGIS-------EP 930

Query: 221  SEAADEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENA 280
                 + ++P +N++   +++ +  KK     +  +FGQ                     
Sbjct: 931  GNQEKKSEKPLENDTGLQAQDISGRKKG----RGVIFGQ--------------------- 965

Query: 281  GHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDAN 340
                    T++ +    ++ S              F       E++ S    ++    AN
Sbjct: 966  --------TSSTFTFADVAKSTSGEGFQFGKKDLNFKGFSGAGEKLFS----SQYGKMAN 1013

Query: 341  RENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQ 400
            + N + +   +  + +     +   E             + EKVE++TGEE E  +    
Sbjct: 1014 KANTSGDFEKDDDAYKTEDSDDIHFEPVVQ---------MPEKVELVTGEEGEKVLYSQG 1064

Query: 401  CKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQI 460
             KLF FD     W ERG G L++  + +  +G +  R++M+ +  L++  N  +   M +
Sbjct: 1065 VKLFRFDAEVSQWKERGLGNLKI--LKNEVNGKV--RMLMQREQVLKVCANHWITTTMNL 1120

Query: 461  D--KASEKSIRITAMDTEDQGVKVFLISASSK 490
                 S+++   +A D  D   K+  ++A  K
Sbjct: 1121 KPLSGSDRAWMWSASDFSDGDAKLERLAAKFK 1152



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 55/224 (24%), Positives = 96/224 (42%), Gaps = 36/224 (16%)

Query: 263  DRVKLINESVDEADMENAGH--PSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQ 320
            D   L  +++D++   ++ H  P A +P   N F         +   S   S+  F    
Sbjct: 1250 DNYDLREDALDDSVSSSSVHASPLASSPVRKNLF---------HFDESTTGSNFSFKSAL 1300

Query: 321  NMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCL 380
            ++S+   SP KLN+  +           G++  S + T E+E   +             L
Sbjct: 1301 SLSK---SPAKLNQSGTSV---------GTDEES-DVTQEEERDGQYFEPVVP------L 1341

Query: 381  LEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVM 440
             + VEV +GEE E  V   + + + +DK    W ERG G +++  + + D+  +  R++M
Sbjct: 1342 PDLVEVSSGEENEQVVFSHRAEFYRYDKDVGQWKERGIGDIKI--LQNYDNKHV--RILM 1397

Query: 441  RTQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKV 482
            R    L+L  N ++   M +   K +E+    TA D  D   KV
Sbjct: 1398 RRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKV 1441



 Score = 30.4 bits (67), Expect = 4.5
 Identities = 20/84 (23%), Positives = 35/84 (41%)

Query: 300  SSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATP 359
            SS   +T  A  S  KFVFG    +R+ S  K    +   +    +    S ++  ++  
Sbjct: 1523 SSTSETTTKAVVSPPKFVFGSESVKRIFSSEKSKPFAFGNSSATGSLFGFSFNAPLKSNN 1582

Query: 360  EKESLAESAAAYTKATARKCLLEK 383
             + S    + + +K   +KC L K
Sbjct: 1583 SETSSVAQSGSESKVEPKKCELSK 1606


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 77/314 (24%), Positives = 113/314 (35%), Gaps = 39/314 (12%)

Query: 61   HALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVK 120
            HA E P  A    STP  PA  A   P P E    +A   +PE                 
Sbjct: 982  HAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPE----------------- 1024

Query: 121  RERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPS-QKPKEQQRSVLRPAVLQA 179
             E TS     PP    E  +      PT     +P+A +P+ ++P     +V  P    +
Sbjct: 1025 -EPTSPAAAVPP---PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1080

Query: 180  PQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEEKEPQKNESSNAS 239
            P     +   P+S    V  P + T    AA P      SP+ A    +EP    ++  +
Sbjct: 1081 PAAAVPTPEEPTSPAAAVPTPEEPTSPA-AAVPTPEEPASPAAAVPTPEEPASPAAAVPT 1139

Query: 240  EEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPT-ATNYFLQYI 298
             EE      PA     V         +  + +V     E +  P+A  PT A +     +
Sbjct: 1140 PEE------PAFPAPAV-----PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAV 1188

Query: 299  SSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSE--SSSQE 356
             ++LE  T+ A +          + E   + P  +  +S+     AAA S  E  +S   
Sbjct: 1189 VATLEEPTSPAASVPTPAAMVATLEE--FTSPAASVPTSEEPASLAAAVSNPEEPTSPAA 1246

Query: 357  ATPEKESLAESAAA 370
            A P  E    SAAA
Sbjct: 1247 AVPTLEEPTSSAAA 1260



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 76/334 (22%), Positives = 118/334 (35%), Gaps = 42/334 (12%)

Query: 50   HGTGHPESAGEHALEPPAPAGASASTPPP--PAPEAQLPPFPRELAGRSAGGSSPEGGED 107
            H    P++A      P  PA  +A+ P P  P   A   P P E    +A    PE    
Sbjct: 982  HAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPE---- 1037

Query: 108  SDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPS-QKPKE 166
             +        P   E TS     P   + E  +      PT     +P+A +P+ ++P  
Sbjct: 1038 -EPTSPAAAVPTPEEPTSPAAAVP---TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1093

Query: 167  QQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPAD-CTGAVPAASPDTAAWRSPSEAAD 225
               +V  P    +P     +   P+S    V  P +  + A    +P+  A+ +P+    
Sbjct: 1094 PAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTP 1153

Query: 226  EEK--------EPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADM 277
            EE          P+++ S  A+     E    A   A    +       +   +   A +
Sbjct: 1154 EESASAAVAVPTPEESASPAAAVPTPAESASFAAVVA-TLEEPTSPAASVPTPAAMVATL 1212

Query: 278  ENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSS 337
            E    P+A  PT+            E   + A A SN     +  +    + P L E +S
Sbjct: 1213 EEFTSPAASVPTS------------EEPASLAAAVSNP----EEPTSPAAAVPTLEEPTS 1256

Query: 338  DANRENAAAESGSESSSQEAT-PEKESLAESAAA 370
             A    AA  +  E SS  A+ P  E  A  AAA
Sbjct: 1257 SA----AAVLTPEELSSPAASVPTPEEPASPAAA 1286



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 55/250 (22%), Positives = 83/250 (33%), Gaps = 27/250 (10%)

Query: 10   PAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAE-APHHGTGHPESAGEHALEPPAP 68
            PA A P            P  ++  S +   P  E   +P      PE     A   P P
Sbjct: 1068 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTP 1127

Query: 69   AGASASTPPPPAPEAQ-----LPPFPRELAGRSAG------GSSPEGGEDSDREDGNYCP 117
               ++     P PE         P P E A  +         +SP     +  E  ++  
Sbjct: 1128 EEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAA 1187

Query: 118  PVK--RERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLP-SQKPKEQQRSVLRP 174
             V    E TS     P   +            TL    +P+A +P S++P     +V  P
Sbjct: 1188 VVATLEEPTSPAASVPTPAA---------MVATLEEFTSPAASVPTSEEPASLAAAVSNP 1238

Query: 175  AVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAAS-PDTAAWRSPSEAADEEKEPQKN 233
                +P     +   P+S    V  P + +   PAAS P      SP+ A    +EP   
Sbjct: 1239 EEPTSPAAAVPTLEEPTSSAAAVLTPEELSS--PAASVPTPEEPASPAAAVSNLEEPASP 1296

Query: 234  ESSNASEEEA 243
             ++  + E A
Sbjct: 1297 AAAVPTPEVA 1306


>gi|150418007 RAN binding protein 2 [Homo sapiens]
          Length = 3224

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 35/111 (31%), Positives = 57/111 (51%), Gaps = 6/111 (5%)

Query: 382  EKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMR 441
            EKVE++TGEE E  +   + KLF FD     W ERG G L++  + +  +G L  R++MR
Sbjct: 2021 EKVELVTGEEDEKVLYSQRVKLFRFDAEVSQWKERGLGNLKI--LKNEVNGKL--RMLMR 2076

Query: 442  TQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKVFLISASSK 490
             +  L++  N  +   M +     S+++    A D  D   K+  ++A  K
Sbjct: 2077 REQVLKVCANHWITTTMNLKPLSGSDRAWMWLASDFSDGDAKLEQLAAKFK 2127



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 52/183 (28%), Positives = 81/183 (44%), Gaps = 24/183 (13%)

Query: 308  SADASSNKFVFGQNMS------ERVLSPPKLNEVSSDANRENAAAESGSESSSQEATPEK 361
            S+    N F FG++ +      +  LSP K     S A    +    G++  S + T E+
Sbjct: 2250 SSPVRKNLFRFGESTTGFNFSFKSALSPSK-----SPAKLNQSGTSVGTDEES-DVTQEE 2303

Query: 362  ESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLL 421
            E   +             L + VEV +GEE E  V   + KL+ +DK    W ERG G +
Sbjct: 2304 ERDGQYFEPVVP------LPDLVEVSSGEENEQVVFSHRAKLYRYDKDVGQWKERGIGDI 2357

Query: 422  RLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQG 479
            ++  + + D+   Q R+VMR    L+L  N ++   M +   K +E+    TA D  D  
Sbjct: 2358 KI--LQNYDN--KQVRIVMRRDQVLKLCANHRITPDMTLQNMKGTERVWLWTACDFADGE 2413

Query: 480  VKV 482
             KV
Sbjct: 2414 RKV 2416



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 33/101 (32%), Positives = 54/101 (53%), Gaps = 6/101 (5%)

Query: 380  LLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLV 439
            L +K+EV TGEE E      + KLF FD  S+ W ERG G +++  +     G +  RL+
Sbjct: 1178 LPDKIEVKTGEEDEEEFFCNRAKLFRFDVESKEWKERGIGNVKI--LRHKTSGKI--RLL 1233

Query: 440  MRTQGSLRLILNTKLWAQMQI--DKASEKSIRITAMDTEDQ 478
            MR +  L++  N  +   M++  +  S++S    A+D  D+
Sbjct: 1234 MRREQVLKICANHYISPDMKLTPNAGSDRSFVWHALDYADE 1274



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 29/106 (27%), Positives = 51/106 (48%), Gaps = 10/106 (9%)

Query: 381  LEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRL--NDMASTDDGTLQSRL 438
            L +VEV +GEE E  + + + KL+ +D+    W ERG G +++  + M +        R+
Sbjct: 2918 LPEVEVKSGEEDEEILFKERAKLYRWDRDVSQWKERGVGDIKILWHTMKN------YYRI 2971

Query: 439  VMRTQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKV 482
            +MR     ++  N  +   M++     S  ++  TA D  D   KV
Sbjct: 2972 LMRRDQVFKVCANHVITKTMELKPLNVSNNALVWTASDYADGEAKV 3017


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 93/433 (21%), Positives = 153/433 (35%), Gaps = 77/433 (17%)

Query: 20  QKDKGQKSPAEQKNLSDSGEE-----PRGEAEAPHHGTGHP-----------ESAGEHAL 63
           ++++G++    ++  ++ GEE     P  EA +P      P           +S  +   
Sbjct: 479 KEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEA 538

Query: 64  EPPAPAGASASTPPPPAPEAQLPPF----PRELAGRSAGGSSPEGGEDSDREDG------ 113
           + PA   +      P   EA+ PP      +E A   A   SPE  +   +E+       
Sbjct: 539 KSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEA 598

Query: 114 ----NYCPPVKRERTSSLTQFPPSQSEERS-----SGFRLKPPTLIHGQAP-SAGLPSQK 163
                   PVK E  S      P + E +S     S  + K PT    ++P  A  P ++
Sbjct: 599 KSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKE 658

Query: 164 PKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEA 223
             +       P   +A  P+     V           A+      A SP     +SP +A
Sbjct: 659 EAKSPEKAKSPVKAEAKSPEKAKSPV----------KAEAKSPEKAKSPVKEEAKSPEKA 708

Query: 224 ----ADEEKEPQKNESSNASEEEACEK-KDPATQQAFVFGQNLRDRVKLINESVDEADME 278
                +E K P+K +S    E +  EK K P  ++A        ++ K    S ++A   
Sbjct: 709 KSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA-----KSPEKAK----SPEKAKTL 759

Query: 279 NAGHPSADTP------TATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKL 332
           +   P A TP      +  + F +   S ++    S + + +         E+ +  PK 
Sbjct: 760 DVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEI--PKK 817

Query: 333 NEVSSDANRENAAAE-------SGSESSSQEATPEKESLAES--AAAYTKATARKCLLEK 383
            EV S    E    E         +E     ATP+ E   +S    A  K   +  + EK
Sbjct: 818 EEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEK 877

Query: 384 VEVITGEEAESNV 396
            E    +  ES V
Sbjct: 878 KEPAVEKPKESKV 890



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 76/378 (20%), Positives = 138/378 (36%), Gaps = 38/378 (10%)

Query: 8   EKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPA 67
           ++ A +PP     + +  KSPAE K+   +    + EA++P       ++      E  +
Sbjct: 555 KEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS 614

Query: 68  PAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDG----NYCPPVKRER 123
           PA A +         A++    +  +       SPE  +  ++E+         PVK E 
Sbjct: 615 PAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA 674

Query: 124 TSSLTQFPPSQSEERS-------------SGFRLKPPTLIHGQAP-SAGLPSQKPKEQQR 169
            S      P ++E +S             S  + K P     ++P  A  P ++  +   
Sbjct: 675 KSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPE 734

Query: 170 SVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASP-DTAAWRSPSEAADEEK 228
               P   +A  P+       +   +  S  A       A SP D    ++ S   +E K
Sbjct: 735 KAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVK 794

Query: 229 EPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTP 288
            P+K +S    + +A EK+ P  ++       +++  K     V E   +     +  TP
Sbjct: 795 SPEKAKSPLKEDAKAPEKEIPKKEEV---KSPVKEEEKPQEVKVKEPPKKAEEEKAPATP 851

Query: 289 TATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAES 348
                  +    S +      +A   K    +   E  +  PK ++V  +A +E A    
Sbjct: 852 KT-----EEKKDSKKEEAPKKEAPKPKV---EEKKEPAVEKPKESKV--EAKKEEA---- 897

Query: 349 GSESSSQEATPEKESLAE 366
             E   +  TPEKE+ A+
Sbjct: 898 --EDKKKVPTPEKEAPAK 913



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 75/366 (20%), Positives = 130/366 (35%), Gaps = 52/366 (14%)

Query: 26  KSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPP----PPAP 81
           KSPAE K+   +    + EA++P       +   +   +  +P  A A +P     P   
Sbjct: 627 KSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKA 686

Query: 82  EAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCP----PVKRE-RTSSLTQFP----- 131
           EA+ P   +      A   SPE  +   +E+         PVK E +T    + P     
Sbjct: 687 EAKSPEKAKSPVKEEA--KSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA 744

Query: 132 ----PSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQ 187
                ++S E++    +K P         A  P+ K  E+ +S ++  V    + K+  +
Sbjct: 745 KSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLK 804

Query: 188 TVPSSGTNGVSLPADCTGAVPAAS-PDTAAWRSPSEAADEEKEP---QKNESSNASEEEA 243
               +    +    +    V     P     + P + A+EEK P   +  E  ++ +EEA
Sbjct: 805 EDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEA 864

Query: 244 CEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFLQYISSSLE 303
            +K+ P  +      +     V+   ES  EA  E A                      +
Sbjct: 865 PKKEAPKPKVE----EKKEPAVEKPKESKVEAKKEEA------------------EDKKK 902

Query: 304 NSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATPEKES 363
             T   +A +   V      +    P +  EV+     +  A E    +  +EA PEK+ 
Sbjct: 903 VPTPEKEAPAKVEV------KEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKD 956

Query: 364 LAESAA 369
             E  A
Sbjct: 957 TKEEKA 962



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 71/309 (22%), Positives = 115/309 (37%), Gaps = 56/309 (18%)

Query: 91  ELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLI 150
           E   +   G   EGGE+ + E G        E T S    PP++ E  S     K P   
Sbjct: 475 EKEAKEEEGKEEEGGEEEEAEGGE-------EETKS----PPAE-EAASPEKEAKSPV-- 520

Query: 151 HGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAA 210
                         KE+ +S   PA  ++P+ +                PA+      A 
Sbjct: 521 --------------KEEAKS---PAEAKSPEKEEAKS------------PAEVKSPEKAK 551

Query: 211 SPDTAAWRSPSEAADEEKEPQKNESSNASEEEACEKKDPATQQA-----FVFGQNLRDRV 265
           SP     +SP EA   EKE  K+ +   S E+A   K PA ++A         +  +  V
Sbjct: 552 SPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKA---KSPAKEEAKSPAEAKSPEKAKSPV 608

Query: 266 KLINESVDEADMENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSER 325
           K   E+   A+ ++     A +P       +  S + E + +   A S +    ++  E+
Sbjct: 609 K--EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKS-PEK 665

Query: 326 VLSPPKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVE 385
             SP K    S +  +    AE+ S   ++    E+    E A +  K  A+    EK +
Sbjct: 666 AKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKS--PEKAK 723

Query: 386 VITGEEAES 394
               EEA++
Sbjct: 724 SPVKEEAKT 732



 Score = 33.5 bits (75), Expect = 0.53
 Identities = 64/271 (23%), Positives = 96/271 (35%), Gaps = 57/271 (21%)

Query: 26  KSPA-EQKNLSDSGEEP-RGEAEAPHHGTGHPESAGEHALEPP---APAGASASTPPPPA 80
           KSP  E+    +  + P + EA++P      PE A    ++ P    PA   A +P    
Sbjct: 723 KSPVKEEAKTPEKAKSPVKEEAKSPEKAKS-PEKAKTLDVKSPEAKTPAKEEARSPADKF 781

Query: 81  PEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGN-----------YCPPVKRERTSSLTQ 129
           PE    P   E+        SPE  +   +ED                PVK E      +
Sbjct: 782 PEKAKSPVKEEV-------KSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVK 834

Query: 130 F--PPSQSEERSSGFRLKPPTLIHG---QAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKA 184
              PP ++EE  +    K          +AP    P  K +E++     PAV +  + K 
Sbjct: 835 VKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKE----PAVEKPKESKV 890

Query: 185 LSQTVPSSGTNGVSLPADCTGA---------------VPAASPDTAAWRSPSEAADE--- 226
            ++   +     V  P     A               V    PD A  + PS+ A++   
Sbjct: 891 EAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEA 950

Query: 227 --EKEPQKNESSNASEE----EACEKKDPAT 251
             EK+  K E +   EE    EA  K+D  T
Sbjct: 951 APEKKDTKEEKAKKPEEKPKTEAKAKEDDKT 981


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 95/427 (22%), Positives = 158/427 (37%), Gaps = 76/427 (17%)

Query: 5   ANEEKPA-IAPPVFVFQKDKGQKSPAEQKNLS---DSGEEPRGEAEAPHHGTGHPESAGE 60
           + E+ PA I PP+      K +  PAE+ ++     + E P  EA               
Sbjct: 261 STEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAAT------------- 307

Query: 61  HALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSS---------PEGGEDSDRE 111
                 A A  S    PPPA EA L  FP E+   SA  S          P   E+S  E
Sbjct: 308 ------AVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSE 361

Query: 112 D--GNYCPPVKRE----------RTSSLTQFP------PSQSEERSSGFRLKPPTLIHGQ 153
           +      PP   +          R+ S  + P      P++     +  +++PPT+    
Sbjct: 362 EPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETL 421

Query: 154 AP-SAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASP 212
           A     LP + P+E+ R +     ++ P  +A ++           LP + T    +A  
Sbjct: 422 ADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQS-------PLPKETTAEEASAEI 474

Query: 213 DTAAWRSP--SEAADEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINE 270
              A   P   E   E + P   E+S  +EE   E + P  ++     +     ++L+  
Sbjct: 475 QLLAATEPPADETPAEARSPLSEETS--AEEAHAEVQSPLAEE--TTAEEASAEIQLL-- 528

Query: 271 SVDEADMENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPP 330
           +  EA       P+ +TP      L   +S+ E        S+      +   E  L PP
Sbjct: 529 AAIEA-------PADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLE--LQPP 579

Query: 331 KLNEVSSDANRENAAAESGSESSSQEATPE-KESLAESAAAYTKATARKCLLEKVEVITG 389
              E +++         + +E+S++EA  E +   AE A A  +    +    +V+    
Sbjct: 580 SGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPA 639

Query: 390 EEAESNV 396
           EEA + V
Sbjct: 640 EEAPAEV 646



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 45/188 (23%), Positives = 68/188 (36%), Gaps = 24/188 (12%)

Query: 8   EKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPA 67
           E+ + A  +    +   +++PAE         +P    EAP      P       ++PP 
Sbjct: 587 EEASAAIQLLAATEASAEEAPAEV--------QPPPAEEAPAEVQPPPAEEAPAEVQPPP 638

Query: 68  PAGASASTPPPPAPE--AQLPPFPRELAGRSAGGSSPEGGEDSDREDGNY-CPPVKRERT 124
              A A   PPPA E  A++ P P E A        P   E++  E  +        E T
Sbjct: 639 AEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEV---QPPPAEEAPAEVQSLPAEETPIEET 695

Query: 125 SSLTQFPPSQ---SEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQ 181
            +    PP+    +EE S      P  L+  +    G       E    V  P   Q P+
Sbjct: 696 LAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIG-------EASAEVSPPPSEQTPE 748

Query: 182 PKALSQTV 189
            +AL + V
Sbjct: 749 DEALVENV 756



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 45/173 (26%), Positives = 62/173 (35%), Gaps = 20/173 (11%)

Query: 7   EEKPAIA-PPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEP 65
           EE PA   PP       + Q  PAE+   + +  +P    EAP      P       ++P
Sbjct: 604 EEAPAEVQPPPAEEAPAEVQPPPAEE---APAEVQPPPAEEAPAEVQPPPAEEAPAEVQP 660

Query: 66  PAPAGASASTPPPPAPEA-----QLPPFPRELAGRSAGGSSPEGGEDSDREDGN---YCP 117
           P    A A   PPPA EA      LP     +    A   SP   +D   E+ +   + P
Sbjct: 661 PPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPP-ADDVPAEEASVDKHSP 719

Query: 118 PVKRERTSSL------TQFPPSQSEERSSGFRLKPPTLIHGQAPS-AGLPSQK 163
           P     T          +  P  SE+      L        Q+P  AG+P+ K
Sbjct: 720 PADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQVAGIPAVK 772


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 74/361 (20%), Positives = 137/361 (37%), Gaps = 51/361 (14%)

Query: 55  PESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGN 114
           P++A  +  + PAP   +   P P  P+   P  P+E A  +  G++P     + +E   
Sbjct: 535 PKAAAPNTPKEPAPT--TPKEPAPTTPKEPAPTTPKETAPTTPKGTAP----TTLKEPAP 588

Query: 115 YCP--PVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQ----KPKEQQ 168
             P  P  +E   + T+ P S + ++ +    K       + P+   P +     PK   
Sbjct: 589 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 648

Query: 169 RSVLR---PAVLQAPQPKALSQTV---PSSGTNGVSLPADCTGAVPAA--SPDTAAWRSP 220
            + L+   P   + P PK L+ T    P+S T+    P       P     P     + P
Sbjct: 649 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 708

Query: 221 SEAADEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENA 280
           +    E   P  +E S  +       K+P T    +         +L  E   +A +EN+
Sbjct: 709 APTTPETPPPTTSEVSTPT-----TTKEPTT----IHKSPDESTPELSAEPTPKA-LENS 758

Query: 281 ----GHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVS 336
               G P+  TP AT           E +T + D ++ + +  +   E   + PK+ + +
Sbjct: 759 PKEPGVPTTKTPAAT---------KPEMTTTAKDKTTERDL--RTTPETTTAAPKMTKET 807

Query: 337 SDANRE------NAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGE 390
           +    +       A     + +++Q+ TP K +  ++     K T  K  +   E++   
Sbjct: 808 ATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP 867

Query: 391 E 391
           E
Sbjct: 868 E 868



 Score = 37.0 bits (84), Expect = 0.048
 Identities = 43/199 (21%), Positives = 68/199 (34%), Gaps = 14/199 (7%)

Query: 65  PPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERT 124
           P  PA  +   P P  P+   P  P+E A  +    SP   ++         P   +E  
Sbjct: 345 PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA 404

Query: 125 SSLTQFPPSQSEERSSGFRLKP-PTLIHGQAPS-----AGLPSQKPKEQQRSVLRPAVLQ 178
            + T+  P+  +E S     +P PT     AP+     A    ++P         P   +
Sbjct: 405 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 464

Query: 179 APQPKALSQTVPSS-GTNGVSLPADCTGAVP----AASPDTAAWRSPSEAA---DEEKEP 230
            P P    +  P++      + P   T   P      +P+  A  +P E A    EE  P
Sbjct: 465 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 524

Query: 231 QKNESSNASEEEACEKKDP 249
              E    +  +A     P
Sbjct: 525 TTPEEPAPTTPKAAAPNTP 543



 Score = 36.6 bits (83), Expect = 0.063
 Identities = 70/341 (20%), Positives = 116/341 (34%), Gaps = 62/341 (18%)

Query: 52  TGHPESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDRE 111
           T  P S       P  P G + +TP  PAP       P+E A  +  G++P     + +E
Sbjct: 604 TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT-----PKEPAPTTPKGTAP----TTLKE 654

Query: 112 DGNYCP--PVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQR 169
                P  P  +E   + T+ P S + ++ +      PT     AP+       PKE   
Sbjct: 655 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPA------PTTPKETAPTT------PKE--- 699

Query: 170 SVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADE-EK 228
               PA     +P   +   P   T+ VS P             T   +SP E+  E   
Sbjct: 700 ----PAPTTPKKPAPTTPETPPPTTSEVSTPT-------TTKEPTTIHKSPDESTPELSA 748

Query: 229 EPQKNESSNASEEEAC-EKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADT 287
           EP      N+ +E      K PA  +         +      +   E D+      +   
Sbjct: 749 EPTPKALENSPKEPGVPTTKTPAATKP--------EMTTTAKDKTTERDLRTTPETTTAA 800

Query: 288 PTATNYFLQYISSSLEN----------STNSADASSNKF--VFGQNMSERVLSPPKLNEV 335
           P  T         + E+          ST + D +  K   +    ++ +V +  K    
Sbjct: 801 PKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITT 860

Query: 336 SSDANRENAAAESGSESSSQEAT---PEKESLAESAAAYTK 373
           +   N+    A+    +++ +AT   P+K + A      TK
Sbjct: 861 TEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTK 901



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 48/234 (20%), Positives = 77/234 (32%), Gaps = 12/234 (5%)

Query: 25  QKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPP----PPA 80
           + +P   K+   + +EP          T   E A     EP      SA T P    P  
Sbjct: 246 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 305

Query: 81  PEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSS 140
           P+   P  P+E A  +    +P   ++         P   +E   +  + P   + +  +
Sbjct: 306 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 365

Query: 141 GFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQP---KALSQTVPSSGTNGV 197
               K P     + PS   P +      +S   P   + P P   K+   T         
Sbjct: 366 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA--PTTTKEPAPTTTKSAPTTPKEPSPTTT 423

Query: 198 SLPADCTGAVPA-ASPDTAAWRSPSEAADEEKEPQKNESSNASEEEACEKKDPA 250
             PA  T   PA  +P   A  +P E A     P++   +   +      K+PA
Sbjct: 424 KEPAPTTPKEPAPTTPKKPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPA 475


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 74/361 (20%), Positives = 137/361 (37%), Gaps = 51/361 (14%)

Query: 55  PESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGN 114
           P++A  +  + PAP   +   P P  P+   P  P+E A  +  G++P     + +E   
Sbjct: 576 PKAAAPNTPKEPAPT--TPKEPAPTTPKEPAPTTPKETAPTTPKGTAP----TTLKEPAP 629

Query: 115 YCP--PVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQ----KPKEQQ 168
             P  P  +E   + T+ P S + ++ +    K       + P+   P +     PK   
Sbjct: 630 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 689

Query: 169 RSVLR---PAVLQAPQPKALSQTV---PSSGTNGVSLPADCTGAVPAA--SPDTAAWRSP 220
            + L+   P   + P PK L+ T    P+S T+    P       P     P     + P
Sbjct: 690 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 749

Query: 221 SEAADEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENA 280
           +    E   P  +E S  +       K+P T    +         +L  E   +A +EN+
Sbjct: 750 APTTPETPPPTTSEVSTPT-----TTKEPTT----IHKSPDESTPELSAEPTPKA-LENS 799

Query: 281 ----GHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVS 336
               G P+  TP AT           E +T + D ++ + +  +   E   + PK+ + +
Sbjct: 800 PKEPGVPTTKTPAAT---------KPEMTTTAKDKTTERDL--RTTPETTTAAPKMTKET 848

Query: 337 SDANRE------NAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGE 390
           +    +       A     + +++Q+ TP K +  ++     K T  K  +   E++   
Sbjct: 849 ATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP 908

Query: 391 E 391
           E
Sbjct: 909 E 909



 Score = 37.0 bits (84), Expect = 0.048
 Identities = 43/199 (21%), Positives = 68/199 (34%), Gaps = 14/199 (7%)

Query: 65  PPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERT 124
           P  PA  +   P P  P+   P  P+E A  +    SP   ++         P   +E  
Sbjct: 386 PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA 445

Query: 125 SSLTQFPPSQSEERSSGFRLKP-PTLIHGQAPS-----AGLPSQKPKEQQRSVLRPAVLQ 178
            + T+  P+  +E S     +P PT     AP+     A    ++P         P   +
Sbjct: 446 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 505

Query: 179 APQPKALSQTVPSS-GTNGVSLPADCTGAVP----AASPDTAAWRSPSEAA---DEEKEP 230
            P P    +  P++      + P   T   P      +P+  A  +P E A    EE  P
Sbjct: 506 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 565

Query: 231 QKNESSNASEEEACEKKDP 249
              E    +  +A     P
Sbjct: 566 TTPEEPAPTTPKAAAPNTP 584



 Score = 36.6 bits (83), Expect = 0.063
 Identities = 70/341 (20%), Positives = 116/341 (34%), Gaps = 62/341 (18%)

Query: 52  TGHPESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDRE 111
           T  P S       P  P G + +TP  PAP       P+E A  +  G++P     + +E
Sbjct: 645 TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT-----PKEPAPTTPKGTAP----TTLKE 695

Query: 112 DGNYCP--PVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQR 169
                P  P  +E   + T+ P S + ++ +      PT     AP+       PKE   
Sbjct: 696 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPA------PTTPKETAPTT------PKE--- 740

Query: 170 SVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADE-EK 228
               PA     +P   +   P   T+ VS P             T   +SP E+  E   
Sbjct: 741 ----PAPTTPKKPAPTTPETPPPTTSEVSTPT-------TTKEPTTIHKSPDESTPELSA 789

Query: 229 EPQKNESSNASEEEAC-EKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADT 287
           EP      N+ +E      K PA  +         +      +   E D+      +   
Sbjct: 790 EPTPKALENSPKEPGVPTTKTPAATKP--------EMTTTAKDKTTERDLRTTPETTTAA 841

Query: 288 PTATNYFLQYISSSLEN----------STNSADASSNKF--VFGQNMSERVLSPPKLNEV 335
           P  T         + E+          ST + D +  K   +    ++ +V +  K    
Sbjct: 842 PKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITT 901

Query: 336 SSDANRENAAAESGSESSSQEAT---PEKESLAESAAAYTK 373
           +   N+    A+    +++ +AT   P+K + A      TK
Sbjct: 902 TEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTK 942



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 48/234 (20%), Positives = 77/234 (32%), Gaps = 12/234 (5%)

Query: 25  QKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPP----PPA 80
           + +P   K+   + +EP          T   E A     EP      SA T P    P  
Sbjct: 287 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 346

Query: 81  PEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSS 140
           P+   P  P+E A  +    +P   ++         P   +E   +  + P   + +  +
Sbjct: 347 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 406

Query: 141 GFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQP---KALSQTVPSSGTNGV 197
               K P     + PS   P +      +S   P   + P P   K+   T         
Sbjct: 407 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA--PTTTKEPAPTTTKSAPTTPKEPSPTTT 464

Query: 198 SLPADCTGAVPA-ASPDTAAWRSPSEAADEEKEPQKNESSNASEEEACEKKDPA 250
             PA  T   PA  +P   A  +P E A     P++   +   +      K+PA
Sbjct: 465 KEPAPTTPKEPAPTTPKKPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPA 516


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 74/361 (20%), Positives = 137/361 (37%), Gaps = 51/361 (14%)

Query: 55  PESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGN 114
           P++A  +  + PAP   +   P P  P+   P  P+E A  +  G++P     + +E   
Sbjct: 628 PKAAAPNTPKEPAPT--TPKEPAPTTPKEPAPTTPKETAPTTPKGTAP----TTLKEPAP 681

Query: 115 YCP--PVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQ----KPKEQQ 168
             P  P  +E   + T+ P S + ++ +    K       + P+   P +     PK   
Sbjct: 682 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 741

Query: 169 RSVLR---PAVLQAPQPKALSQTV---PSSGTNGVSLPADCTGAVPAA--SPDTAAWRSP 220
            + L+   P   + P PK L+ T    P+S T+    P       P     P     + P
Sbjct: 742 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 801

Query: 221 SEAADEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENA 280
           +    E   P  +E S  +       K+P T    +         +L  E   +A +EN+
Sbjct: 802 APTTPETPPPTTSEVSTPT-----TTKEPTT----IHKSPDESTPELSAEPTPKA-LENS 851

Query: 281 ----GHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVS 336
               G P+  TP AT           E +T + D ++ + +  +   E   + PK+ + +
Sbjct: 852 PKEPGVPTTKTPAAT---------KPEMTTTAKDKTTERDL--RTTPETTTAAPKMTKET 900

Query: 337 SDANRE------NAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGE 390
           +    +       A     + +++Q+ TP K +  ++     K T  K  +   E++   
Sbjct: 901 ATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP 960

Query: 391 E 391
           E
Sbjct: 961 E 961



 Score = 37.0 bits (84), Expect = 0.048
 Identities = 43/199 (21%), Positives = 68/199 (34%), Gaps = 14/199 (7%)

Query: 65  PPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERT 124
           P  PA  +   P P  P+   P  P+E A  +    SP   ++         P   +E  
Sbjct: 438 PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA 497

Query: 125 SSLTQFPPSQSEERSSGFRLKP-PTLIHGQAPS-----AGLPSQKPKEQQRSVLRPAVLQ 178
            + T+  P+  +E S     +P PT     AP+     A    ++P         P   +
Sbjct: 498 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 557

Query: 179 APQPKALSQTVPSS-GTNGVSLPADCTGAVP----AASPDTAAWRSPSEAA---DEEKEP 230
            P P    +  P++      + P   T   P      +P+  A  +P E A    EE  P
Sbjct: 558 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 617

Query: 231 QKNESSNASEEEACEKKDP 249
              E    +  +A     P
Sbjct: 618 TTPEEPAPTTPKAAAPNTP 636



 Score = 36.6 bits (83), Expect = 0.063
 Identities = 70/341 (20%), Positives = 116/341 (34%), Gaps = 62/341 (18%)

Query: 52  TGHPESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDRE 111
           T  P S       P  P G + +TP  PAP       P+E A  +  G++P     + +E
Sbjct: 697 TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT-----PKEPAPTTPKGTAP----TTLKE 747

Query: 112 DGNYCP--PVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQR 169
                P  P  +E   + T+ P S + ++ +      PT     AP+       PKE   
Sbjct: 748 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPA------PTTPKETAPTT------PKE--- 792

Query: 170 SVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADE-EK 228
               PA     +P   +   P   T+ VS P             T   +SP E+  E   
Sbjct: 793 ----PAPTTPKKPAPTTPETPPPTTSEVSTPT-------TTKEPTTIHKSPDESTPELSA 841

Query: 229 EPQKNESSNASEEEAC-EKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADT 287
           EP      N+ +E      K PA  +         +      +   E D+      +   
Sbjct: 842 EPTPKALENSPKEPGVPTTKTPAATKP--------EMTTTAKDKTTERDLRTTPETTTAA 893

Query: 288 PTATNYFLQYISSSLEN----------STNSADASSNKF--VFGQNMSERVLSPPKLNEV 335
           P  T         + E+          ST + D +  K   +    ++ +V +  K    
Sbjct: 894 PKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITT 953

Query: 336 SSDANRENAAAESGSESSSQEAT---PEKESLAESAAAYTK 373
           +   N+    A+    +++ +AT   P+K + A      TK
Sbjct: 954 TEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTK 994



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 48/234 (20%), Positives = 77/234 (32%), Gaps = 12/234 (5%)

Query: 25  QKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPP----PPA 80
           + +P   K+   + +EP          T   E A     EP      SA T P    P  
Sbjct: 339 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 398

Query: 81  PEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSS 140
           P+   P  P+E A  +    +P   ++         P   +E   +  + P   + +  +
Sbjct: 399 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 458

Query: 141 GFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQP---KALSQTVPSSGTNGV 197
               K P     + PS   P +      +S   P   + P P   K+   T         
Sbjct: 459 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA--PTTTKEPAPTTTKSAPTTPKEPSPTTT 516

Query: 198 SLPADCTGAVPA-ASPDTAAWRSPSEAADEEKEPQKNESSNASEEEACEKKDPA 250
             PA  T   PA  +P   A  +P E A     P++   +   +      K+PA
Sbjct: 517 KEPAPTTPKEPAPTTPKKPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPA 568


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 74/361 (20%), Positives = 137/361 (37%), Gaps = 51/361 (14%)

Query: 55   PESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGN 114
            P++A  +  + PAP   +   P P  P+   P  P+E A  +  G++P     + +E   
Sbjct: 669  PKAAAPNTPKEPAPT--TPKEPAPTTPKEPAPTTPKETAPTTPKGTAP----TTLKEPAP 722

Query: 115  YCP--PVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQ----KPKEQQ 168
              P  P  +E   + T+ P S + ++ +    K       + P+   P +     PK   
Sbjct: 723  TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 782

Query: 169  RSVLR---PAVLQAPQPKALSQTV---PSSGTNGVSLPADCTGAVPAA--SPDTAAWRSP 220
             + L+   P   + P PK L+ T    P+S T+    P       P     P     + P
Sbjct: 783  PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 842

Query: 221  SEAADEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENA 280
            +    E   P  +E S  +       K+P T    +         +L  E   +A +EN+
Sbjct: 843  APTTPETPPPTTSEVSTPT-----TTKEPTT----IHKSPDESTPELSAEPTPKA-LENS 892

Query: 281  ----GHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVS 336
                G P+  TP AT           E +T + D ++ + +  +   E   + PK+ + +
Sbjct: 893  PKEPGVPTTKTPAAT---------KPEMTTTAKDKTTERDL--RTTPETTTAAPKMTKET 941

Query: 337  SDANRE------NAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGE 390
            +    +       A     + +++Q+ TP K +  ++     K T  K  +   E++   
Sbjct: 942  ATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP 1001

Query: 391  E 391
            E
Sbjct: 1002 E 1002



 Score = 37.0 bits (84), Expect = 0.048
 Identities = 43/199 (21%), Positives = 68/199 (34%), Gaps = 14/199 (7%)

Query: 65  PPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERT 124
           P  PA  +   P P  P+   P  P+E A  +    SP   ++         P   +E  
Sbjct: 479 PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA 538

Query: 125 SSLTQFPPSQSEERSSGFRLKP-PTLIHGQAPS-----AGLPSQKPKEQQRSVLRPAVLQ 178
            + T+  P+  +E S     +P PT     AP+     A    ++P         P   +
Sbjct: 539 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 598

Query: 179 APQPKALSQTVPSS-GTNGVSLPADCTGAVP----AASPDTAAWRSPSEAA---DEEKEP 230
            P P    +  P++      + P   T   P      +P+  A  +P E A    EE  P
Sbjct: 599 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 658

Query: 231 QKNESSNASEEEACEKKDP 249
              E    +  +A     P
Sbjct: 659 TTPEEPAPTTPKAAAPNTP 677



 Score = 36.6 bits (83), Expect = 0.063
 Identities = 70/341 (20%), Positives = 116/341 (34%), Gaps = 62/341 (18%)

Query: 52   TGHPESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDRE 111
            T  P S       P  P G + +TP  PAP       P+E A  +  G++P     + +E
Sbjct: 738  TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT-----PKEPAPTTPKGTAP----TTLKE 788

Query: 112  DGNYCP--PVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQR 169
                 P  P  +E   + T+ P S + ++ +      PT     AP+       PKE   
Sbjct: 789  PAPTTPKKPAPKELAPTTTKGPTSTTSDKPA------PTTPKETAPTT------PKE--- 833

Query: 170  SVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADE-EK 228
                PA     +P   +   P   T+ VS P             T   +SP E+  E   
Sbjct: 834  ----PAPTTPKKPAPTTPETPPPTTSEVSTPT-------TTKEPTTIHKSPDESTPELSA 882

Query: 229  EPQKNESSNASEEEAC-EKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADT 287
            EP      N+ +E      K PA  +         +      +   E D+      +   
Sbjct: 883  EPTPKALENSPKEPGVPTTKTPAATKP--------EMTTTAKDKTTERDLRTTPETTTAA 934

Query: 288  PTATNYFLQYISSSLEN----------STNSADASSNKF--VFGQNMSERVLSPPKLNEV 335
            P  T         + E+          ST + D +  K   +    ++ +V +  K    
Sbjct: 935  PKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITT 994

Query: 336  SSDANRENAAAESGSESSSQEAT---PEKESLAESAAAYTK 373
            +   N+    A+    +++ +AT   P+K + A      TK
Sbjct: 995  TEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTK 1035



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 48/234 (20%), Positives = 77/234 (32%), Gaps = 12/234 (5%)

Query: 25  QKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPP----PPA 80
           + +P   K+   + +EP          T   E A     EP      SA T P    P  
Sbjct: 380 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 439

Query: 81  PEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSS 140
           P+   P  P+E A  +    +P   ++         P   +E   +  + P   + +  +
Sbjct: 440 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 499

Query: 141 GFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQP---KALSQTVPSSGTNGV 197
               K P     + PS   P +      +S   P   + P P   K+   T         
Sbjct: 500 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA--PTTTKEPAPTTTKSAPTTPKEPSPTTT 557

Query: 198 SLPADCTGAVPA-ASPDTAAWRSPSEAADEEKEPQKNESSNASEEEACEKKDPA 250
             PA  T   PA  +P   A  +P E A     P++   +   +      K+PA
Sbjct: 558 KEPAPTTPKEPAPTTPKKPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPA 609


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 56/236 (23%), Positives = 72/236 (30%), Gaps = 45/236 (19%)

Query: 14  PPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASA 73
           PP     K +G   P + +     G++ R     P    G P   G     PP P G   
Sbjct: 81  PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 140

Query: 74  STPPPPAPEAQLPPFPRELAG-------RSAGGSSPEG------GEDSDREDGNYCPPVK 120
             PP    + Q PP P +  G       +S    SP G       +  ++  G   PP K
Sbjct: 141 GPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGK 200

Query: 121 RE-------------RTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQ 167
            +                   Q PP Q + +S   R  PP    G  P  G   Q P   
Sbjct: 201 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSAR-SPPGKPQGPPPQGGNQPQGP--- 256

Query: 168 QRSVLRPAVLQAPQPKALSQTVPSSGTN---GVSLPADCTGAVPAASPDTAAWRSP 220
                       P P    Q  P  G N   G   P    G  P     + + RSP
Sbjct: 257 ------------PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 48/165 (29%), Positives = 56/165 (33%), Gaps = 35/165 (21%)

Query: 9   KPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAP 68
           KP   PP       K Q  P +  + S S   P G+ + P      P   G     PP P
Sbjct: 273 KPQGPPP-----PGKPQGPPPQGGSKSRSSRSPPGKPQGP------PPQGGNQPQGPPPP 321

Query: 69  AGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLT 128
            G     PP    + Q PP P +       G  P+GG  S        PP K        
Sbjct: 322 PGKPQGPPPQGGNKPQGPPPPGK-----PQGPPPQGGSKSRSARS---PPGK-------P 366

Query: 129 QFPPSQSEERSSGFRLKPPTLIHG-----QAPSAGLPSQKPKEQQ 168
           Q PP Q      G    PP    G     QAP AG P   P+  Q
Sbjct: 367 QGPPQQEGNNPQG----PPPPAGGNPQQPQAPPAGQPQGPPRPPQ 407



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 55/215 (25%), Positives = 67/215 (31%), Gaps = 52/215 (24%)

Query: 38  GEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTP---------PPPAPEAQLPP- 87
           G +P+G    P    G P   G     PP P G     P         PPP  + Q PP 
Sbjct: 44  GNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 103

Query: 88  ------FPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRE-------------RTSSLT 128
                  PR   G+   G  P+GG   ++  G   PP K +                   
Sbjct: 104 QGDKSRSPRSPPGKPQ-GPPPQGG---NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 159

Query: 129 QFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQT 188
           Q PP Q + +S   R  PP    G  P  G   Q P               P P    Q 
Sbjct: 160 QGPPPQGDNKSRSSR-SPPGKPQGPPPQGGNQPQGP---------------PPPPGKPQG 203

Query: 189 VPSSGTN---GVSLPADCTGAVPAASPDTAAWRSP 220
            P  G N   G   P    G  P     + + RSP
Sbjct: 204 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP 238



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 62/267 (23%), Positives = 84/267 (31%), Gaps = 33/267 (12%)

Query: 9   KPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAP-----HHGTGHPESAGEHAL 63
           KP   PP       K Q  P +  N S S   P G+ + P     +   G P   G+   
Sbjct: 149 KPQGPPP-----PGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 203

Query: 64  EPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEG--GEDSDREDGNYCPPVKR 121
            PP         PPP  P+   P    +     +    P+G   +  ++  G   PP K 
Sbjct: 204 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGK- 262

Query: 122 ERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQA-- 179
                  Q PP Q   +  G    PP    G  P  G  S+  +        P       
Sbjct: 263 ------PQGPPPQGGNKPQG--PPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQ 314

Query: 180 ----PQPKALSQTVPSSGTN---GVSLPADCTGAVPAASPDTAAWRSPSEAADEEKEPQK 232
               P P    Q  P  G N   G   P    G  P     + + RSP     + + P +
Sbjct: 315 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSP---PGKPQGPPQ 371

Query: 233 NESSNASEEEACEKKDPATQQAFVFGQ 259
            E +N          +P   QA   GQ
Sbjct: 372 QEGNNPQGPPPPAGGNPQQPQAPPAGQ 398



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 41/173 (23%), Positives = 62/173 (35%), Gaps = 19/173 (10%)

Query: 32  KNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPPPAPEAQLPPFP-- 89
           +NL++   +    +    +  G P   G     PP+P G     PP    + Q PP P  
Sbjct: 17  QNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPG 76

Query: 90  RELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSS------LTQFPPSQSEERSSGFR 143
           +       GG+ P+G     +  G   PP + +++ S        Q PP Q   +  G  
Sbjct: 77  KPQGPPPQGGNKPQGPPPPGKPQG---PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG-P 132

Query: 144 LKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNG 196
             PP    G  P  G   Q P         P   Q P P+  +++  S    G
Sbjct: 133 PPPPGKPQGPPPQGGNKPQGPPP-------PGKPQGPPPQGDNKSRSSRSPPG 178


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 55/211 (26%), Positives = 70/211 (33%), Gaps = 31/211 (14%)

Query: 38  GEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPP-------PAPEAQLPPFPR 90
           G +P+     P    G P   G  +  PP P G     PP        P P    P  P 
Sbjct: 44  GNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPP 103

Query: 91  ELAGRSAGGSSPEGG--EDSDREDGNYC-----PPVKRERTSSLTQFPPSQSEERSS--- 140
              G  + G+ P  G  E    + GN       PP K ER       PP Q   +S    
Sbjct: 104 PQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPER-------PPPQGGNQSQGPP 156

Query: 141 ---GFRLKPPTLIHGQAPSAGLPSQKPK-EQQRSVLRPAVLQAPQPKALSQTVPSSGTNG 196
              G    PP     ++ SA  P  KP+   Q+   +P   Q P P    Q  P +G N 
Sbjct: 157 PHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKP---QGPPPPGKPQGPPPAGGNP 213

Query: 197 VSLPADCTGAVPAASPDTAAWRSPSEAADEE 227
               A   G      P     R P  A  ++
Sbjct: 214 QQPQAPPAGKPQGPPPPPQGGRPPRPAQGQQ 244



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 56/219 (25%), Positives = 74/219 (33%), Gaps = 39/219 (17%)

Query: 35  SDSGEEPRGEAEAPHHGTGHPES----AGEHALEPPAPAGASASTPPPPAPEAQLPPFPR 90
           ++S  E   + E+    +G PE      G     PP P G     PP    ++Q PP P 
Sbjct: 16  AESSSEDVSQEESLFLISGKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPP- 74

Query: 91  ELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGF------RL 144
              G+   G  P+GG  S    G    P K ER       PP Q   +S G         
Sbjct: 75  --PGKPE-GRPPQGGNQS---QGPPPHPGKPER-------PPPQGGNQSQGTPPPPGKPE 121

Query: 145 KPP----TLIHGQAPSAGLPSQKP----KEQQRSVLRPAVLQAPQP----KALSQTVPSS 192
           +PP       H   P  G P + P     + Q     P   + P P    K+ S   P  
Sbjct: 122 RPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPG 181

Query: 193 GTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEEKEPQ 231
              G   P    G  P   P     + P  A    ++PQ
Sbjct: 182 KPQG---PPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQ 217



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 15/86 (17%)

Query: 6   NEEKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEP 65
           N+ + A +PP     K +G   P +Q+     G  P G+ + P    G+P+       +P
Sbjct: 171 NKSRSARSPP----GKPQG---PPQQEGNKPQGPPPPGKPQGPPPAGGNPQ-------QP 216

Query: 66  PAPAGASASTPPPPAPEAQLPPFPRE 91
            AP       PPPP    + PP P +
Sbjct: 217 QAPPAGKPQGPPPPPQGGR-PPRPAQ 241


>gi|239747210 PREDICTED: hypothetical protein XP_002346689 [Homo
           sapiens]
          Length = 275

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 45/177 (25%), Positives = 69/177 (38%), Gaps = 13/177 (7%)

Query: 8   EKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALE--- 64
           +K +  P     Q D+G   PAE     D G  P  E +       HP +  +  ++   
Sbjct: 32  DKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGS 91

Query: 65  -PPAPAGA--SASTPPPPAPEAQLPPF---PRELAGRSAGGSSPEGGEDSDREDGNYCPP 118
            PPA         + PP   + Q+      P EL G+  GGS P    D  + DG   PP
Sbjct: 92  RPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDGQMDGGSRPPAELDG-QMDGGSRPP 150

Query: 119 VKRERTSSLTQFPPSQSE-ERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRP 174
            + +        PP++ + +  +G R  PP  + GQ  +   P  +   Q  +  RP
Sbjct: 151 AELDGQMDTGSRPPAELDGQMDTGSR--PPAELDGQMDTGSRPPAELDGQTDTGSRP 205



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 45/175 (25%), Positives = 69/175 (39%), Gaps = 20/175 (11%)

Query: 20  QKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALE----PPAPAGA--SA 73
           Q D G + PAE     D G  P GE +    G   P +  +  ++    PPA        
Sbjct: 86  QMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDG 145

Query: 74  STPPPPAPEAQLPPF---PRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQF 130
            + PP   + Q+      P EL G+   GS P    D   + G+  PP + +  +     
Sbjct: 146 GSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQMDTGSR-PPAELDGQTDTGSR 204

Query: 131 PPSQSE---ERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQP 182
           PP++ +   +R S    +PP  + GQ  +   P   P E    +  P +LQ   P
Sbjct: 205 PPAELDGQMDRGS----RPPAELDGQMDTGSRP---PAELALPMPPPEMLQLGAP 252



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 41/165 (24%), Positives = 64/165 (38%), Gaps = 13/165 (7%)

Query: 20  QKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALE----PPAPAGA--SA 73
           Q D+G + PAE     D G  P  E +    G   P +  +  ++    PP         
Sbjct: 58  QMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMDG 117

Query: 74  STPPPPAPEAQLPPF---PRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQF 130
            + PP   + Q+      P EL G+  GGS P    D   + G+  PP + +        
Sbjct: 118 GSRPPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSR-PPAELDGQMDTGSR 176

Query: 131 PPSQSE-ERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRP 174
           PP++ + +  +G R  PP  + GQ  +   P  +   Q     RP
Sbjct: 177 PPAELDGQMDTGSR--PPAELDGQTDTGSRPPAELDGQMDRGSRP 219


>gi|157266273 RANBP2-like and GRIP domain containing 1 [Homo sapiens]
          Length = 1756

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 6/111 (5%)

Query: 382  EKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMR 441
            EKVE++TGEE E  +     KLF FD     W ERG G L++  + +  +G  + R++MR
Sbjct: 1038 EKVELVTGEEGEKVLYSQGVKLFRFDAEISQWKERGLGNLKI--LKNEVNG--KPRMLMR 1093

Query: 442  TQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKVFLISASSK 490
                L++  N  +   M +     S+++    A D  D   K+  ++A  K
Sbjct: 1094 RDQVLKVCANHWITTTMNLKPLSGSDRAWMWLASDFSDGDAKLERLAAQFK 1144



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 63/258 (24%), Positives = 110/258 (42%), Gaps = 36/258 (13%)

Query: 227  EKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSAD 286
            E+E + + +  A   +   K +P      +   N   R   ++++V  + + ++  P A 
Sbjct: 1210 EEENKGSGTGAAGASDTTIKPNPENTGPTLEWDNYDLREDALDDNVSSSSVHDS--PLAS 1267

Query: 287  TPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAA 346
            +P   N F        + ST   + S   F    ++S+   SP KLN+  +         
Sbjct: 1268 SPVRKNIF------RFDESTTGFNFS---FKSALSLSK---SPAKLNQSGTSV------- 1308

Query: 347  ESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVF 406
              G++  S + T E+E   +             L + VEV +GEE E  V   + +L+ +
Sbjct: 1309 --GTDEES-DVTQEEERDGQYFEPVVP------LPDLVEVSSGEENEQVVFSHRAELYRY 1359

Query: 407  DKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQID--KAS 464
            DK    W ERG G +++  + + D+   Q R+VMR    L+L  N ++   M +   K +
Sbjct: 1360 DKDVGQWKERGIGDIKI--LQNYDN--KQVRIVMRRDQVLKLCANHRITPDMSLQNMKGT 1415

Query: 465  EKSIRITAMDTEDQGVKV 482
            E+    TA D  D   KV
Sbjct: 1416 ERVWVWTACDFADGERKV 1433



 Score = 33.1 bits (74), Expect = 0.70
 Identities = 21/84 (25%), Positives = 36/84 (42%)

Query: 300  SSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATP 359
            SS   +T  A  S  KFVFG    +R+ S  K N  +   +    +    S ++  ++  
Sbjct: 1515 SSTSETTTKAVVSPPKFVFGSESVKRIFSSEKSNPFAFGNSSATGSLFGFSFNAPLKSND 1574

Query: 360  EKESLAESAAAYTKATARKCLLEK 383
             + S    + + +K   +KC L K
Sbjct: 1575 SETSSVAQSGSESKVEPKKCELSK 1598


>gi|118200331 RANBP2-like and GRIP domain containing 2 [Homo
           sapiens]
          Length = 1013

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 6/111 (5%)

Query: 382 EKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMR 441
           EKVE++TGEE E  +     KLF FD     W ERG G L++  + +  +G  + R++MR
Sbjct: 295 EKVELVTGEEGEKVLYSQGVKLFRFDAEISQWKERGLGNLKI--LKNEVNG--KPRMLMR 350

Query: 442 TQGSLRLILNTKLWAQMQID--KASEKSIRITAMDTEDQGVKVFLISASSK 490
               L++  N  +   M +     S+++    A D  D   K+  ++A  K
Sbjct: 351 RDQVLKVCANHWITTTMNLKPLSGSDRAWMWLASDFSDGDAKLERLAAQFK 401



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 63/258 (24%), Positives = 109/258 (42%), Gaps = 36/258 (13%)

Query: 227 EKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSAD 286
           E+E + + +  A   +   K +P      +   N   R   ++++V  + + ++  P A 
Sbjct: 467 EEENKGSGTGAAGASDTTIKPNPENTGPTLEWDNYDLREDALDDNVSSSSVHDS--PLAS 524

Query: 287 TPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAA 346
           +P   N F        + ST   + S   F    ++S+   SP KLN+  +         
Sbjct: 525 SPVRKNIF------RFDESTTGFNFS---FKSALSLSK---SPAKLNQSGTSV------- 565

Query: 347 ESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVF 406
             G++  S + T E+E   +             L + VEV +GEE E  V     +L+ +
Sbjct: 566 --GTDEES-DVTQEEERDGQYFEPVVP------LPDLVEVSSGEENEQVVFSHMAELYRY 616

Query: 407 DKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQID--KAS 464
           DK    W ERG G +++  + + D+   Q R+VMR    L+L  N ++   M +   K +
Sbjct: 617 DKDVGQWKERGIGDIKI--LQNYDN--KQVRIVMRRDQVLKLCANHRITPDMSLQNMKGT 672

Query: 465 EKSIRITAMDTEDQGVKV 482
           E+    TA D  D   KV
Sbjct: 673 ERVWVWTACDFADGERKV 690



 Score = 33.1 bits (74), Expect = 0.70
 Identities = 21/84 (25%), Positives = 36/84 (42%)

Query: 300 SSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATP 359
           SS   +T  A  S  KFVFG    +R+ S  K N  +   +    +    S ++  ++  
Sbjct: 772 SSTSETTTKAVVSPPKFVFGSESVKRIFSSEKSNPFAFGNSSATGSLFGFSFNAPLKSND 831

Query: 360 EKESLAESAAAYTKATARKCLLEK 383
            + S    + + +K   +KC L K
Sbjct: 832 SETSSVAQSGSESKVEPKKCELSK 855


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.305    0.122    0.339 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,403,443
Number of Sequences: 37866
Number of extensions: 1496122
Number of successful extensions: 15587
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 208
Number of HSP's successfully gapped in prelim test: 1020
Number of HSP's that attempted gapping in prelim test: 10374
Number of HSP's gapped (non-prelim): 4545
length of query: 562
length of database: 18,247,518
effective HSP length: 107
effective length of query: 455
effective length of database: 14,195,856
effective search space: 6459114480
effective search space used: 6459114480
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.