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Search of human proteins with 193788653
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|193788653 hypothetical protein LOC100131897 [Homo sapiens]
(535 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|193788653 hypothetical protein LOC100131897 [Homo sapiens] 1077 0.0
gi|89886201 hypothetical protein LOC642938 [Homo sapiens] 120 3e-27
gi|83779010 SECIS binding protein 2 [Homo sapiens] 45 2e-04
gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens] 44 5e-04
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 43 8e-04
gi|226442791 runt-related transcription factor 2 isoform b [Homo... 42 0.001
gi|226442783 runt-related transcription factor 2 isoform a [Homo... 42 0.001
gi|66934969 runt-related transcription factor 2 isoform c [Homo ... 42 0.001
gi|33598950 podocalyxin-like isoform 2 precursor [Homo sapiens] 42 0.001
gi|66277202 podocalyxin-like isoform 1 precursor [Homo sapiens] 42 0.001
gi|4758024 coilin [Homo sapiens] 42 0.001
gi|75750472 spectrin domain with coiled-coils 1 NSP5b3b [Homo sa... 40 0.004
gi|75750466 spectrin domain with coiled-coils 1 NSP5b3a [Homo sa... 40 0.004
gi|49472835 bridging integrator 2 [Homo sapiens] 38 0.020
gi|157738639 tensin 4 [Homo sapiens] 38 0.027
gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo sa... 38 0.027
gi|75750468 spectrin domain with coiled-coils 1 NSP5a3a [Homo sa... 38 0.027
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 38 0.027
gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo s... 37 0.059
gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo sa... 37 0.059
gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo sa... 37 0.059
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 36 0.077
gi|229577185 epidermal growth factor receptor pathway substrate ... 36 0.077
gi|4503593 epidermal growth factor receptor pathway substrate 15... 36 0.077
gi|46195763 metastasis suppressor 1-like [Homo sapiens] 36 0.077
gi|42518068 trans-golgi network protein 2 [Homo sapiens] 36 0.10
gi|216547801 SH2 domain containing 3C isoform e [Homo sapiens] 36 0.10
gi|216547790 SH2 domain containing 3C isoform d [Homo sapiens] 36 0.10
gi|216547779 SH2 domain containing 3C isoform c [Homo sapiens] 36 0.10
gi|216547769 SH2 domain containing 3C isoform c [Homo sapiens] 36 0.10
>gi|193788653 hypothetical protein LOC100131897 [Homo sapiens]
Length = 535
Score = 1077 bits (2786), Expect = 0.0
Identities = 535/535 (100%), Positives = 535/535 (100%)
Query: 1 MAQQNMKVRPVLLKRNSLESVEFVKQPHHRRSKSQQVRFKEDGTTKNPTGLAEVDVQTPE 60
MAQQNMKVRPVLLKRNSLESVEFVKQPHHRRSKSQQVRFKEDGTTKNPTGLAEVDVQTPE
Sbjct: 1 MAQQNMKVRPVLLKRNSLESVEFVKQPHHRRSKSQQVRFKEDGTTKNPTGLAEVDVQTPE 60
Query: 61 DPAVMGKTQATRHHLPPTYSLSFPRSQKAGGFRNIAIQTSPSLRKHFPVFKRKRLTASKS 120
DPAVMGKTQATRHHLPPTYSLSFPRSQKAGGFRNIAIQTSPSLRKHFPVFKRKRLTASKS
Sbjct: 61 DPAVMGKTQATRHHLPPTYSLSFPRSQKAGGFRNIAIQTSPSLRKHFPVFKRKRLTASKS 120
Query: 121 LVEMPTASQSAIQVNGNLSEQDIVSSDLAYLRLAQHLEDGPRRVKVSHAFLPRVPKVQSN 180
LVEMPTASQSAIQVNGNLSEQDIVSSDLAYLRLAQHLEDGPRRVKVSHAFLPRVPKVQSN
Sbjct: 121 LVEMPTASQSAIQVNGNLSEQDIVSSDLAYLRLAQHLEDGPRRVKVSHAFLPRVPKVQSN 180
Query: 181 GPVSICLEAGTWRSLEKATAAIQVPDDIYHSPSWEARESALSPDRSAEVSNSIHPLDDTR 240
GPVSICLEAGTWRSLEKATAAIQVPDDIYHSPSWEARESALSPDRSAEVSNSIHPLDDTR
Sbjct: 181 GPVSICLEAGTWRSLEKATAAIQVPDDIYHSPSWEARESALSPDRSAEVSNSIHPLDDTR 240
Query: 241 PGDGRRVTPLDSEKSTSCLNATSVASHTPGTEELKPELLLPKDNSDDKDLGSLSSQSKET 300
PGDGRRVTPLDSEKSTSCLNATSVASHTPGTEELKPELLLPKDNSDDKDLGSLSSQSKET
Sbjct: 241 PGDGRRVTPLDSEKSTSCLNATSVASHTPGTEELKPELLLPKDNSDDKDLGSLSSQSKET 300
Query: 301 CVPSSPRTHSSPSQGSHSQPAHPGRASDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTAN 360
CVPSSPRTHSSPSQGSHSQPAHPGRASDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTAN
Sbjct: 301 CVPSSPRTHSSPSQGSHSQPAHPGRASDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTAN 360
Query: 361 NPTESDTLEFPNCPGSNHLPSSLSRSETKLQSNREISDINQIHLARGELCDLQGRLQSVE 420
NPTESDTLEFPNCPGSNHLPSSLSRSETKLQSNREISDINQIHLARGELCDLQGRLQSVE
Sbjct: 361 NPTESDTLEFPNCPGSNHLPSSLSRSETKLQSNREISDINQIHLARGELCDLQGRLQSVE 420
Query: 421 ESLHSNQEKIKVLLNVIQDLEKARALTEGRNFYRTGQDLNNCSTCQNTACIIYSVEYDFR 480
ESLHSNQEKIKVLLNVIQDLEKARALTEGRNFYRTGQDLNNCSTCQNTACIIYSVEYDFR
Sbjct: 421 ESLHSNQEKIKVLLNVIQDLEKARALTEGRNFYRTGQDLNNCSTCQNTACIIYSVEYDFR 480
Query: 481 QQEGRFHEVLQSLEEAEPVEEASPPPKSPAEPPAPEKQDLRRKTKKVKKKCFWWI 535
QQEGRFHEVLQSLEEAEPVEEASPPPKSPAEPPAPEKQDLRRKTKKVKKKCFWWI
Sbjct: 481 QQEGRFHEVLQSLEEAEPVEEASPPPKSPAEPPAPEKQDLRRKTKKVKKKCFWWI 535
>gi|89886201 hypothetical protein LOC642938 [Homo sapiens]
Length = 479
Score = 120 bits (301), Expect = 3e-27
Identities = 133/513 (25%), Positives = 196/513 (38%), Gaps = 80/513 (15%)
Query: 30 RRSKSQQVRFKEDGTTKNP---TGLAEVDVQTPEDPAVMGKTQATRHHLPPTYSLSFPRS 86
+R+K+ QVRFK+ +N T L+ + + + A R ++ S P
Sbjct: 40 KRNKALQVRFKDICEAQNEQRDTQLSSGQLGEKREAKPVSCRAAYRKYMTVPARRSIPNV 99
Query: 87 QKAGGFRNIAIQTSPSLRKHFPVFKRKRLTASKSLVEMPTASQSAIQVNGNLSEQDIVSS 146
K+ G +QTSP L+K + F R + L +P A Q NG
Sbjct: 100 TKSTG-----VQTSPDLKKCYQTFPLDRKKGN--LKSLPAADPFKSQNNG---------- 142
Query: 147 DLAYLRLAQHLEDGPRRVKVSHAFLPRVPKVQSNGPVSICLEAGTWRSLEKATAAIQVPD 206
FL + GP+ G R + K TA + +
Sbjct: 143 -----------------------FLTDAKEKNEAGPMEEARPCGAGR-VHKTTALVFHSN 178
Query: 207 DIYHSPSWEARESALSPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVAS 266
++ + P +S E PL P E L
Sbjct: 179 QHMNTVDQPLGVNCTEPCKSPE------PLSYGEAALQNSTRPPSEEPDYQLLGRAKQDR 232
Query: 267 HTPGTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRA 326
P +EE P L + E +P + + S A +
Sbjct: 233 GRPNSEEPAPPALRRVFKT-------------EVATVYAPALSARAPEPGLSDSAAASQW 279
Query: 327 SDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSR- 385
S CP+ + + S++A C P + + E P H P L
Sbjct: 280 SLCPADDERRRATHLNGLQAPSETALACSP-----PMQCLSPECSEQPSQTHTPPGLGNQ 334
Query: 386 -SETKLQSNREISDINQIHLARGELCDLQGRLQSVEESLHSNQEKIKVLLNVIQDLEKAR 444
S T + + E I + E+ DL+ +LQ +E + S+QE IKVLL VIQ+LEK
Sbjct: 335 PSPTAVAAGEECQRI----VPHTEVVDLKAQLQMMENLISSSQETIKVLLGVIQELEKGE 390
Query: 445 ALTEGRNFYRTGQDLNNCSTCQNTACIIYSVEYDFRQQEGRFHEVLQSLEEAEPVEEAS- 503
A EG + YRTGQD NC TC+N+ACIIYSVE DF+QQE + VL+ L P+EE
Sbjct: 391 AHREGLS-YRTGQDTANCDTCRNSACIIYSVELDFKQQEDKLQPVLRKL---HPIEETQV 446
Query: 504 -PPPKSPAEPPAPEKQDLRRKTKKVKKKCFWWI 535
P P S + KQ + ++KK + W++
Sbjct: 447 IPSPYSQETYSSTPKQKSKTESKKHGRWKLWFL 479
>gi|83779010 SECIS binding protein 2 [Homo sapiens]
Length = 854
Score = 44.7 bits (104), Expect = 2e-04
Identities = 41/142 (28%), Positives = 58/142 (40%), Gaps = 9/142 (6%)
Query: 294 SSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRASDCPSSSNNHQNLVSLKT-NSASKSAP 352
S+ K +PSS S PS HP + S S+ QN S K KS
Sbjct: 331 SADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKSTS 390
Query: 353 GCQEQTANNPTE-SDTLEFPNCPGSNHLPSSLSRSET-KLQSNREISDINQIHLARGEL- 409
+ T P D EFPN ++ R ET K QS ++ D + ++ + +L
Sbjct: 391 KYEVLTVQEPPRIEDAEEFPNLAVAS---ERRDRIETPKFQSKQQPQDNFKNNVKKSQLP 447
Query: 410 --CDLQGRLQSVEESLHSNQEK 429
DL G L ++E+ HS K
Sbjct: 448 VQLDLGGMLTALEKKQHSQHAK 469
>gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]
Length = 1243
Score = 43.5 bits (101), Expect = 5e-04
Identities = 56/197 (28%), Positives = 75/197 (38%), Gaps = 43/197 (21%)
Query: 215 EARESALSP-DRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVASHTPGTEE 273
EA E LSP + A + PL D + + T L+ T A S +S +PGT
Sbjct: 756 EAAEDTLSPQEEPAPLPALPVPLPDPSNEELQSSTSLEHRSWT----AFSTSSSSPGTP- 810
Query: 274 LKP----------------ELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTH--SSPSQG 315
L P + P + +SSQ V S+P H SSP
Sbjct: 811 LSPGNPFSPGTPISPGPIFPITSPPCHPSPSPFSPISSQ-----VSSNPSPHPTSSPLPF 865
Query: 316 SHSQPAHPGRASDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPG 375
S S P P S CP S SL T S +P C + T ++P FP CP
Sbjct: 866 SSSTPEFPVPLSQCPWS--------SLPTTSPPTFSPTCSQVTLSSPF------FPPCPS 911
Query: 376 SNHLPSSLSRSETKLQS 392
++ PS+ + L S
Sbjct: 912 TSSFPSTTAAPLLSLAS 928
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 42.7 bits (99), Expect = 8e-04
Identities = 42/187 (22%), Positives = 78/187 (41%), Gaps = 13/187 (6%)
Query: 211 SPSWEARESALSPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVASHTPG 270
S S ++ +S+ S D S++ SNS D + D DS S+ N++ + +
Sbjct: 762 SNSSDSSDSSDSSD-SSDSSNSSDSNDSSNSSDSS-----DSSNSSDSSNSSDSSDSSDS 815
Query: 271 TEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRASDCP 330
++ NS D S SS S + S S S S + +SD
Sbjct: 816 SDS-------DSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS 868
Query: 331 SSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSRSETKL 390
SS++ + S ++ +++S+ ++N ++SD+ + N S+ +S SE+
Sbjct: 869 DSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSN 928
Query: 391 QSNREIS 397
S+ S
Sbjct: 929 SSDNSNS 935
Score = 41.6 bits (96), Expect = 0.002
Identities = 44/193 (22%), Positives = 85/193 (44%), Gaps = 13/193 (6%)
Query: 206 DDIYHSPSWEARESALSPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVA 265
DD S S + + + D S++ SNS D + DS+ S S ++ S +
Sbjct: 535 DDNDKSDSGKGKSDSSDSD-SSDSSNSSDSSDSS-----------DSDSSDSNSSSDSDS 582
Query: 266 SHTPGTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGR 325
S + ++ + ++SD D S SS S ++ S ++ SS S+ S
Sbjct: 583 SDSDSSDSSDSDSSDSSNSSDSSD-SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSD 641
Query: 326 ASDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSR 385
+SD SS ++ + S +NS++ S ++++ + SD+ + S+ +S
Sbjct: 642 SSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSES 701
Query: 386 SETKLQSNREISD 398
S++ S+ + SD
Sbjct: 702 SDSSDSSDSDSSD 714
Score = 40.8 bits (94), Expect = 0.003
Identities = 43/195 (22%), Positives = 82/195 (42%), Gaps = 13/195 (6%)
Query: 207 DIYHSPSWEARESALSPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVAS 266
D S S ++ +S+ S ++ SNS D + D + DS S+ +++ ++
Sbjct: 706 DSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS--DSSNSSDSSDSSDSSN 763
Query: 267 HTPGTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRA 326
+ ++ D+SD D S SS S ++ S S+ S S+S +
Sbjct: 764 SSDSSDS--------SDSSDSSD-SSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSD 814
Query: 327 SDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSRS 386
S SSN+ + S ++ +S S+ +++ ++SD+ SN SS S
Sbjct: 815 SSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSN--RSDSSNSSDSSDSSD 872
Query: 387 ETKLQSNREISDINQ 401
+ + + SD N+
Sbjct: 873 SSNSSDSSDSSDSNE 887
Score = 40.8 bits (94), Expect = 0.003
Identities = 40/188 (21%), Positives = 82/188 (43%), Gaps = 9/188 (4%)
Query: 211 SPSWEARESALSPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVASHTPG 270
S S ++ +S+ S D S++ S+S + D + D + DS S+ +++ ++ +
Sbjct: 729 SNSSDSSDSSNSSD-SSDSSDSSNSSDSSDSSDSSNSS--DSSDSSDSSDSSDSSNSSDS 785
Query: 271 TEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRASDCP 330
+ NS D S SS S ++ S + S + S ++ +SD
Sbjct: 786 NDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845
Query: 331 SSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSRSETKL 390
SS+ + S +++S++ S ++N+ SD+ + SN +S S++
Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD------SNESSNSSDSSDSSN 899
Query: 391 QSNREISD 398
S+ + SD
Sbjct: 900 SSDSDSSD 907
Score = 40.4 bits (93), Expect = 0.004
Identities = 41/190 (21%), Positives = 79/190 (41%), Gaps = 8/190 (4%)
Query: 211 SPSWEARESALSPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVASHTPG 270
S S ++ +S+ S D S S+S D+ D + + + +S + +S +S++
Sbjct: 605 SDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSN 664
Query: 271 TEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRASDCP 330
+ + D+SD D S SS S + S S+ S+ S S + +SD
Sbjct: 665 SSD-------SSDSSDSSDSSS-SSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSS 716
Query: 331 SSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSRSETKL 390
SSN++ + +S S + + + ++ + + + + SN SS S +
Sbjct: 717 DSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDS 776
Query: 391 QSNREISDIN 400
+ SD N
Sbjct: 777 SDSSNSSDSN 786
Score = 40.0 bits (92), Expect = 0.005
Identities = 46/196 (23%), Positives = 78/196 (39%), Gaps = 16/196 (8%)
Query: 207 DIYHSPSWEARESALSPDRSAEVSNSIHPLDDTRPGDGR---------RVTPLDSEKSTS 257
D S S + +S+ S D S++ SNS D + DG DS S+
Sbjct: 814 DSSDSDSSNSSDSSNSSD-SSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD 872
Query: 258 CLNATSVASHTPGTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSH 317
N++ + + E NS D D S+ S SS ++SS S S
Sbjct: 873 SSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS-----DSSDSSNSSDSSES- 926
Query: 318 SQPAHPGRASDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSN 377
S + +SD +SS++ + S ++ +S S+ +++ SD+ + N S+
Sbjct: 927 SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSS 986
Query: 378 HLPSSLSRSETKLQSN 393
S S++ SN
Sbjct: 987 DSSDSSDSSDSSDSSN 1002
Score = 39.3 bits (90), Expect = 0.009
Identities = 43/195 (22%), Positives = 85/195 (43%), Gaps = 12/195 (6%)
Query: 211 SPSWEARESALSPD--RSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVASHT 268
S S ++ +S+ S D S++ S+S D DS S++ +++ + +
Sbjct: 789 SNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSS 848
Query: 269 PGTEE---LKPELLLPKDNSDDKDL--GSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHP 323
G++ + + D+SD D S SS S ++ S+ S S S S +
Sbjct: 849 DGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDS 908
Query: 324 GRASDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSL 383
+SD SSN+ + S ++ S S+ ++N+ SD+ + N S++ S
Sbjct: 909 SNSSDSSDSSNSSDSSESSNSSDNSNSS-----DSSNSSDSSDSSDSSNSSDSSNSSDSS 963
Query: 384 SRSETKLQSNREISD 398
+ S++ ++ + SD
Sbjct: 964 NSSDSSDSNSSDSSD 978
Score = 38.5 bits (88), Expect = 0.016
Identities = 45/183 (24%), Positives = 82/183 (44%), Gaps = 13/183 (7%)
Query: 211 SPSWEARESALSPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVASHTPG 270
S S ++ +S+ S D S + SNS D + D + S+ S S + +S +S +
Sbjct: 771 SDSSDSSDSSNSSD-SNDSSNSSDSSDSSNSSDSSNSSD-SSDSSDSSDSDSSNSSDSSN 828
Query: 271 TEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRASDCP 330
+ + D+S+ D S S + SS R+ SS S S S + +SD
Sbjct: 829 SSD-------SSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDS-SDSSDSSNSSDSS 880
Query: 331 SSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSRSETKL 390
SS+++++ S ++ +S S+ ++N+ SD+ + N S+ +S S +
Sbjct: 881 DSSDSNESSNSSDSSDSSNSSDSDSSDSSNS---SDSSDSSNSSDSSESSNSSDNSNSSD 937
Query: 391 QSN 393
SN
Sbjct: 938 SSN 940
Score = 38.5 bits (88), Expect = 0.016
Identities = 42/188 (22%), Positives = 73/188 (38%), Gaps = 14/188 (7%)
Query: 211 SPSWEARESALSPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVASHTPG 270
S S ++ +S+ S D S++ SNS + + D + DS S+ N++ + +
Sbjct: 780 SNSSDSNDSSNSSD-SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNS 838
Query: 271 TEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSH-----SQPAHPGR 325
++ D+SD D S ++ SS + SS S S S
Sbjct: 839 SDS--------SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSN 890
Query: 326 ASDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSR 385
+SD SSN+ + S +NS+ S ++ + SD + S+ S
Sbjct: 891 SSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDS 950
Query: 386 SETKLQSN 393
S + SN
Sbjct: 951 SNSSDSSN 958
Score = 37.4 bits (85), Expect = 0.035
Identities = 38/164 (23%), Positives = 69/164 (42%), Gaps = 3/164 (1%)
Query: 222 SPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVASHTPGTEEL-KPELLL 280
S R NS D+ D + DS+ ++ N+ S + G ++ K +
Sbjct: 485 SSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGK 544
Query: 281 PKDNSDDKDL--GSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRASDCPSSSNNHQN 338
K +S D D S SS S ++ S ++SS S + SD SSN+ +
Sbjct: 545 GKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDS 604
Query: 339 LVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSS 382
S ++ +S S+ ++ ++ +ESD+ + + S+ SS
Sbjct: 605 SDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSS 648
Score = 37.4 bits (85), Expect = 0.035
Identities = 42/193 (21%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 206 DDIYHSPSWEARESALSPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVA 265
D S S ++ +S+ S D S++ S+S D + D DS S+ ++++ +
Sbjct: 748 DSSNSSDSSDSSDSSNSSD-SSDSSDSSDSSDSSNSSDSN-----DSSNSSDSSDSSNSS 801
Query: 266 SHTPGTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGR 325
+ ++ D+S+ D S SS S ++ S S S GS S ++
Sbjct: 802 DSSNSSDSSDSSDSSDSDSSNSSD-SSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSD 860
Query: 326 ASDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSR 385
+S+ SS++ + +NS+ S +++N+ SD+ + S+ SS S
Sbjct: 861 SSNSSDSSDSSDS-----SNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSS 915
Query: 386 SETKLQSNREISD 398
+ + E S+
Sbjct: 916 DSSNSSDSSESSN 928
Score = 37.0 bits (84), Expect = 0.045
Identities = 40/189 (21%), Positives = 75/189 (39%), Gaps = 4/189 (2%)
Query: 211 SPSWEARESALSPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVASHTPG 270
S S + ES+ S D S S+ ++ D DS S++ +++ + +
Sbjct: 693 SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNS 752
Query: 271 TEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQ-PAHPGRASDC 329
++ NS D S SS S ++ S S+ S S S + +SD
Sbjct: 753 SDSSDSS---DSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDS 809
Query: 330 PSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSRSETK 389
SS++ + S ++S++ S ++++ SD+ + + SN SS S +
Sbjct: 810 SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSD 869
Query: 390 LQSNREISD 398
+ SD
Sbjct: 870 SSDSSNSSD 878
Score = 36.6 bits (83), Expect = 0.059
Identities = 45/192 (23%), Positives = 82/192 (42%), Gaps = 18/192 (9%)
Query: 206 DDIYHSPSWEARESALSPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVA 265
D S S ++ +S+ S D S++ SNS D + D + DS S+ N++ +
Sbjct: 978 DSSNSSDSSDSSDSSDSSD-SSDSSNSSDSSDSSDSSDSSNSS--DSSNSSDSSNSSDSS 1034
Query: 266 SHTPGTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGR 325
+ ++ D+SD D S+ S + SS + SS S S S +
Sbjct: 1035 DSSDSSDS--------SDSSDSSDSSDSSNSSDSS--DSSDSSDSSDSSDS-SDSSDSSE 1083
Query: 326 ASDCPSSSNNHQNLVSLKTNSASKSAPGC----QEQTANNPTESDTLEFPNCPGSNHLPS 381
+SD SSN+ + S ++ +S S+ ++N+ SD+ + + S++
Sbjct: 1084 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143
Query: 382 SLSRSETKLQSN 393
S SE+ S+
Sbjct: 1144 SSDSSESSDSSD 1155
Score = 35.8 bits (81), Expect = 0.10
Identities = 38/188 (20%), Positives = 78/188 (41%), Gaps = 5/188 (2%)
Query: 206 DDIYHSPSWEARESALSPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVA 265
D+ S S + +S+ S D S+ S+S + D + D DS S++ +++ +
Sbjct: 931 DNSNSSDSSNSSDSSDSSD-SSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS 989
Query: 266 SHTPGTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGR 325
+ ++ + D+SD D S+ S + S + S S +
Sbjct: 990 DSSDSSDS--SDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047
Query: 326 ASDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSR 385
+SD SSN+ + S ++ +S S+ ++++ SD+ + N S+ S
Sbjct: 1048 SSDSSDSSNSSDSSDSSDSSDSSDSSD--SSDSSDSSESSDSSDSSNSSDSSDSSDSSDS 1105
Query: 386 SETKLQSN 393
S++ S+
Sbjct: 1106 SDSSDSSD 1113
Score = 35.0 bits (79), Expect = 0.17
Identities = 49/222 (22%), Positives = 86/222 (38%), Gaps = 7/222 (3%)
Query: 211 SPSWEARESALSPDRS-AEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVASHTP 269
S S ++ +S+ S D S ++ SN + + D + +S N +S +S +
Sbjct: 836 SNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSS 895
Query: 270 GTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSH-----SQPAHPG 324
+ NS D S SS S E+ SS ++SS S S S ++
Sbjct: 896 DSSNSSDSDSSDSSNSSDSSDSSNSSDSSESS-NSSDNSNSSDSSNSSDSSDSSDSSNSS 954
Query: 325 RASDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLS 384
+S+ SSN+ + S ++S+ S ++++ SD+ + N S+ S
Sbjct: 955 DSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1014
Query: 385 RSETKLQSNREISDINQIHLARGELCDLQGRLQSVEESLHSN 426
S + SN S + + D S + S SN
Sbjct: 1015 SSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSN 1056
Score = 35.0 bits (79), Expect = 0.17
Identities = 37/187 (19%), Positives = 76/187 (40%), Gaps = 5/187 (2%)
Query: 207 DIYHSPSWEARESALSPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVAS 266
D +S ++ +S+ S D S++ SNS + + D + + +S + +S +S
Sbjct: 896 DSSNSSDSDSSDSSNSSD-SSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS 954
Query: 267 HTPGTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRA 326
+ + + D+SD S S + SS + SS S S + +
Sbjct: 955 DSSNSSDSSNS----SDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1010
Query: 327 SDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSRS 386
SS+++ + S +NS+ S ++++ SD+ + N S+ S S
Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070
Query: 387 ETKLQSN 393
++ S+
Sbjct: 1071 DSSDSSD 1077
Score = 33.5 bits (75), Expect = 0.50
Identities = 38/184 (20%), Positives = 72/184 (39%), Gaps = 2/184 (1%)
Query: 211 SPSWEARESALSPDR-SAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVASHTP 269
S S ++ +S+ S D S++ SNS D + D + S+ S S ++ S S
Sbjct: 889 SNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSN-SSDNSNSSDSSNSSDSSDS 947
Query: 270 GTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRASDC 329
+ D+S+ D +S SS + SS S S +
Sbjct: 948 SDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSS 1007
Query: 330 PSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSRSETK 389
SS ++ + S +NS+ S ++++ SD+ + + S++ S S++
Sbjct: 1008 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1067
Query: 390 LQSN 393
S+
Sbjct: 1068 DSSD 1071
Score = 32.7 bits (73), Expect = 0.85
Identities = 35/179 (19%), Positives = 68/179 (37%), Gaps = 3/179 (1%)
Query: 218 ESALSPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVASHTPGTEELKPE 277
+S + S N + DD D + S+ +S + +S +S + ++
Sbjct: 516 DSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSN 575
Query: 278 LLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRASDCPS---SSN 334
D+SD S S S ++ S S S S S + ++ S SS+
Sbjct: 576 SSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSD 635
Query: 335 NHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSRSETKLQSN 393
+ S +NS+ S ++N+ SD+ + + S+ S + S++ S+
Sbjct: 636 SDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSD 694
Score = 32.3 bits (72), Expect = 1.1
Identities = 29/133 (21%), Positives = 57/133 (42%), Gaps = 5/133 (3%)
Query: 266 SHTPGTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGR 325
S + G E+ + +NSD G+ + + ++ SS S S S ++
Sbjct: 505 SDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDS--SNSSD 562
Query: 326 ASDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSR 385
+SD S ++ N S +S S S+ ++++ SD+ + + S+ S
Sbjct: 563 SSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSS---DSSDS 619
Query: 386 SETKLQSNREISD 398
S++K S++ SD
Sbjct: 620 SDSKSDSSKSESD 632
Score = 32.0 bits (71), Expect = 1.5
Identities = 43/193 (22%), Positives = 81/193 (41%), Gaps = 27/193 (13%)
Query: 211 SPSWEARESALSPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVASHTPG 270
S S ++ +S+ S D S++ SNS D + D DS S+ +++ ++ +
Sbjct: 1073 SDSSDSSDSSESSD-SSDSSNSSDSSDSSDSSDSS-----DSSDSSDSSDSSDSSNSSDS 1126
Query: 271 TEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRASDCP 330
++ D+SD D + S S + SS + SS S S S + +SD
Sbjct: 1127 SDS--------SDSSDSSDSSNSSDSSDSS--ESSDSSDSSDSSDS-SDSSDSSDSSDSS 1175
Query: 331 SSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTE----------SDTLEFPNCPGSNHLP 380
SSN+ + S ++ +S S+ +++ ++ SD+ + + SN
Sbjct: 1176 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESS 1235
Query: 381 SSLSRSETKLQSN 393
S S++ SN
Sbjct: 1236 DSSDSSDSSDSSN 1248
Score = 31.6 bits (70), Expect = 1.9
Identities = 41/188 (21%), Positives = 79/188 (42%), Gaps = 11/188 (5%)
Query: 211 SPSWEARESALSPDRS--AEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVASHT 268
S S ++ +S+ S D S ++ S+S + D + D + +S + +S +S +
Sbjct: 992 SDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1051
Query: 269 PGTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGS--HSQPAHPGRA 326
+ D+SD D S S + SS + SS S S S + +
Sbjct: 1052 SDSSNSSDS----SDSSDSSDSSDSSDSSDSS--DSSESSDSSDSSNSSDSSDSSDSSDS 1105
Query: 327 SDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTE-SDTLEFPNCPGSNHLPSSLSR 385
SD SS++ + S ++ +S S+ ++N ++ SD+ E + S+ S
Sbjct: 1106 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDS 1165
Query: 386 SETKLQSN 393
S++ S+
Sbjct: 1166 SDSSDSSD 1173
Score = 30.8 bits (68), Expect = 3.2
Identities = 42/164 (25%), Positives = 69/164 (42%), Gaps = 11/164 (6%)
Query: 206 DDIYHSPSWEARESALSPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVA 265
D S S ++ +S+ S D S++ S+S D + D + +S + +S +
Sbjct: 1146 DSSESSDSSDSSDSSDSSD-SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1204
Query: 266 SHTPGTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGR 325
S + + + D+SD D S SS S E+ SS + SS S S S +
Sbjct: 1205 SDSSDSSDSSDS----SDSSDSSD-SSDSSDSNESS-DSSDSSDSSDSSNS-SDSSDSSD 1257
Query: 326 ASDCPSSSNNHQNLVSLK---TNSASKSAPGCQEQTANNPTESD 366
+SD S SN+ + S N+ S S + +N+ T D
Sbjct: 1258 SSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 30.4 bits (67), Expect = 4.2
Identities = 38/185 (20%), Positives = 77/185 (41%), Gaps = 5/185 (2%)
Query: 211 SPSWEARESALSPD--RSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVASHT 268
S S ++ +S+ S D S++ SNS D + D + DS S+ N++ + +
Sbjct: 1007 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSS--DSSDSSDSSNSSDSSDSS 1064
Query: 269 PGTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRASD 328
++ +S + S SS S ++ SS + SS S S ++
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS-DSSDSSDSSDSSDSSDSSDSSDSSNS 1123
Query: 329 CPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSRSET 388
SS ++ + S +NS+ S ++++ SD+ + + S+ S + S++
Sbjct: 1124 SDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1183
Query: 389 KLQSN 393
S+
Sbjct: 1184 SDSSD 1188
Score = 30.0 bits (66), Expect = 5.5
Identities = 42/191 (21%), Positives = 81/191 (42%), Gaps = 12/191 (6%)
Query: 211 SPSWEARESALSPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVASHTPG 270
S S ++ +S+ S D S++ S+S D + D DS S+ +++ + +
Sbjct: 1055 SNSSDSSDSSDSSD-SSDSSDSSDSSDSSESSDSS-----DSSNSSDSSDSSDSSDSSDS 1108
Query: 271 TEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRASDCP 330
++ NS D S SS S + SS + SS S S S + +SD
Sbjct: 1109 SDSSDSSDSSDSSNSSDSSDSSDSSDSSD----SSNSSDSSDSSES-SDSSDSSDSSDSS 1163
Query: 331 SSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSRSETKL 390
SS++ + S ++++S S+ +++ ++S + S+ SS S +
Sbjct: 1164 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD-SSDSSDSSDSSDSSDSSDSSDS 1222
Query: 391 QSNREISDINQ 401
+ + SD N+
Sbjct: 1223 SDSSDSSDSNE 1233
>gi|226442791 runt-related transcription factor 2 isoform b [Homo
sapiens]
Length = 499
Score = 42.0 bits (97), Expect = 0.001
Identities = 47/175 (26%), Positives = 75/175 (42%), Gaps = 20/175 (11%)
Query: 215 EARESALSPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVASHTPGTEEL 274
+ R++ SP S + S + T P TPL S + T T V G EL
Sbjct: 287 DPRQAQSSPPWSYDQSYPSYLSQMTSPSI-HSTTPLSSTRGTGLPAITDVPRRISGASEL 345
Query: 275 KPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRASDCPSSSN 334
P SD + S+SS ++ S+PR H P+ +++ P G + ++++
Sbjct: 346 GPF-------SDPRQFPSISSLTESRF--SNPRMHY-PATFTYTPPVTSGMSLGMSATTH 395
Query: 335 NHQNLVS-LKTNSASKSAPGCQEQTANNP-----TESDTLEFPNCPGSNHLPSSL 383
H L +S S+S P QT++ P T S + +FP PG + PS +
Sbjct: 396 YHTYLPPPYPGSSQSQSGPF---QTSSTPYLYYGTSSGSYQFPMVPGGDRSPSRM 447
>gi|226442783 runt-related transcription factor 2 isoform a [Homo
sapiens]
Length = 521
Score = 42.0 bits (97), Expect = 0.001
Identities = 56/197 (28%), Positives = 87/197 (44%), Gaps = 33/197 (16%)
Query: 205 PDDIYHSPSWEARESALSPDRSAEVSNSIH---PLDDTRPGDG--------RRVTPLDSE 253
P SP W +S S S S SIH PL TR G G RR++ D+
Sbjct: 288 PRQAQSSPPWSYDQSYPSY-LSQMTSPSIHSTTPLSSTR-GTGLPAITDVPRRISDDDTA 345
Query: 254 KSTSCLNATSVASHTP-GTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSP 312
S CL ++++ + G EL P SD + S+SS ++ S+PR H P
Sbjct: 346 TSDFCLWPSTLSKKSQAGASELGPF-------SDPRQFPSISSLTESRF--SNPRMHY-P 395
Query: 313 SQGSHSQPAHPGRASDCPSSSNNHQNLVS-LKTNSASKSAPGCQEQTANNP-----TESD 366
+ +++ P G + ++++ H L +S S+S P QT++ P T S
Sbjct: 396 ATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSGPF---QTSSTPYLYYGTSSG 452
Query: 367 TLEFPNCPGSNHLPSSL 383
+ +FP PG + PS +
Sbjct: 453 SYQFPMVPGGDRSPSRM 469
>gi|66934969 runt-related transcription factor 2 isoform c [Homo
sapiens]
Length = 507
Score = 42.0 bits (97), Expect = 0.001
Identities = 56/197 (28%), Positives = 87/197 (44%), Gaps = 33/197 (16%)
Query: 205 PDDIYHSPSWEARESALSPDRSAEVSNSIH---PLDDTRPGDG--------RRVTPLDSE 253
P SP W +S S S S SIH PL TR G G RR++ D+
Sbjct: 274 PRQAQSSPPWSYDQSYPSY-LSQMTSPSIHSTTPLSSTR-GTGLPAITDVPRRISDDDTA 331
Query: 254 KSTSCLNATSVASHTP-GTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSP 312
S CL ++++ + G EL P SD + S+SS ++ S+PR H P
Sbjct: 332 TSDFCLWPSTLSKKSQAGASELGPF-------SDPRQFPSISSLTESRF--SNPRMHY-P 381
Query: 313 SQGSHSQPAHPGRASDCPSSSNNHQNLVS-LKTNSASKSAPGCQEQTANNP-----TESD 366
+ +++ P G + ++++ H L +S S+S P QT++ P T S
Sbjct: 382 ATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSGPF---QTSSTPYLYYGTSSG 438
Query: 367 TLEFPNCPGSNHLPSSL 383
+ +FP PG + PS +
Sbjct: 439 SYQFPMVPGGDRSPSRM 455
>gi|33598950 podocalyxin-like isoform 2 precursor [Homo sapiens]
Length = 526
Score = 42.0 bits (97), Expect = 0.001
Identities = 37/144 (25%), Positives = 67/144 (46%), Gaps = 9/144 (6%)
Query: 228 EVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVASHTPGTEELKPELLLPKDNSDD 287
+VS ++ G G T ++S KST + T+VA+ T KP ++ ++D
Sbjct: 98 QVSGPVNTTVARGGGSGNPTTTIESPKSTKSADTTTVAT---STATAKPNTTSSQNGAED 154
Query: 288 -KDLGSLSSQSKETCVPSSPRTH-SSPSQGSHSQPAHPGRASDCPS-SSNNHQNLVSLKT 344
+ G SS S T + S+ H ++P S P P + +S+ H +L+ + +
Sbjct: 155 TTNSGGKSSHSVTTDLTSTKAEHLTTPHPTSPLSPRQPTSTHPVATPTSSGHDHLMKISS 214
Query: 345 NSASKSAPGCQEQTANNPTESDTL 368
+S++ + PG T +P + TL
Sbjct: 215 SSSTVAIPG---YTFTSPGMTTTL 235
Score = 29.3 bits (64), Expect = 9.4
Identities = 41/188 (21%), Positives = 71/188 (37%), Gaps = 12/188 (6%)
Query: 211 SPSWEARESAL-SPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATS--VASH 267
SPS A ++ S +++A S + T V + + + + AT+ V+S
Sbjct: 29 SPSQNATQTTTDSSNKTAPTPASSVTIMATDTAQQSTVPTSKANEILASVKATTLGVSSD 88
Query: 268 TPGTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRAS 327
+PGT L ++ P + + + GS + + P S ++ + + + + A P S
Sbjct: 89 SPGTTTLAQQVSGPVNTTVARGGGS-GNPTTTIESPKSTKSADTTTVATSTATAKPNTTS 147
Query: 328 DCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSRSE 387
QN TNS KS+ + E T P P S P+S
Sbjct: 148 S--------QNGAEDTTNSGGKSSHSVTTDLTSTKAEHLTTPHPTSPLSPRQPTSTHPVA 199
Query: 388 TKLQSNRE 395
T S +
Sbjct: 200 TPTSSGHD 207
>gi|66277202 podocalyxin-like isoform 1 precursor [Homo sapiens]
Length = 558
Score = 42.0 bits (97), Expect = 0.001
Identities = 37/144 (25%), Positives = 67/144 (46%), Gaps = 9/144 (6%)
Query: 228 EVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVASHTPGTEELKPELLLPKDNSDD 287
+VS ++ G G T ++S KST + T+VA+ T KP ++ ++D
Sbjct: 98 QVSGPVNTTVARGGGSGNPTTTIESPKSTKSADTTTVAT---STATAKPNTTSSQNGAED 154
Query: 288 -KDLGSLSSQSKETCVPSSPRTH-SSPSQGSHSQPAHPGRASDCPS-SSNNHQNLVSLKT 344
+ G SS S T + S+ H ++P S P P + +S+ H +L+ + +
Sbjct: 155 TTNSGGKSSHSVTTDLTSTKAEHLTTPHPTSPLSPRQPTSTHPVATPTSSGHDHLMKISS 214
Query: 345 NSASKSAPGCQEQTANNPTESDTL 368
+S++ + PG T +P + TL
Sbjct: 215 SSSTVAIPG---YTFTSPGMTTTL 235
Score = 29.3 bits (64), Expect = 9.4
Identities = 41/188 (21%), Positives = 71/188 (37%), Gaps = 12/188 (6%)
Query: 211 SPSWEARESAL-SPDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATS--VASH 267
SPS A ++ S +++A S + T V + + + + AT+ V+S
Sbjct: 29 SPSQNATQTTTDSSNKTAPTPASSVTIMATDTAQQSTVPTSKANEILASVKATTLGVSSD 88
Query: 268 TPGTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRAS 327
+PGT L ++ P + + + GS + + P S ++ + + + + A P S
Sbjct: 89 SPGTTTLAQQVSGPVNTTVARGGGS-GNPTTTIESPKSTKSADTTTVATSTATAKPNTTS 147
Query: 328 DCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSRSE 387
QN TNS KS+ + E T P P S P+S
Sbjct: 148 S--------QNGAEDTTNSGGKSSHSVTTDLTSTKAEHLTTPHPTSPLSPRQPTSTHPVA 199
Query: 388 TKLQSNRE 395
T S +
Sbjct: 200 TPTSSGHD 207
>gi|4758024 coilin [Homo sapiens]
Length = 576
Score = 42.0 bits (97), Expect = 0.001
Identities = 51/227 (22%), Positives = 87/227 (38%), Gaps = 27/227 (11%)
Query: 163 RVKVSHAFLPRVPKVQSNGPVSICLEAGTWRSLEKATAAIQVPDDIYHSPSWEARESALS 222
RVK+ + V SNG +++ L R+ + PD Y W++RE+
Sbjct: 82 RVKLEERGVAENSVVISNGDINLSLRKAKKRAFQLEEGEETEPDCKYSKKHWKSREN--- 138
Query: 223 PDRSAEVSNSIHPLDDTRPGDGRRVTPLDSEKSTSCLNATSVASHTPGTEELKPELLLPK 282
+N+ + D P + VT K N + + EE K + K
Sbjct: 139 -------NNNNEKVLDLEP---KAVTDQTVSKKNKRKNKATCGTVGDDNEEAKRKSPKKK 188
Query: 283 DNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSH--SQPAHPGRASDCPSSSNNHQNLV 340
+ + K K+ P SP+ + + S P R S + ++
Sbjct: 189 EKCEYK---------KKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVC 239
Query: 341 SLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSRSE 387
S ++ S+S + C E ++ P++ TLE N S LP+ LS+ E
Sbjct: 240 SKESPSSSSESESCDESISDGPSKV-TLEARN--SSEKLPTELSKEE 283
>gi|75750472 spectrin domain with coiled-coils 1 NSP5b3b [Homo
sapiens]
Length = 1068
Score = 40.4 bits (93), Expect = 0.004
Identities = 79/363 (21%), Positives = 133/363 (36%), Gaps = 60/363 (16%)
Query: 116 TASKSLVEMP-TASQSAIQVNGNLSEQDIVSSDLAYLRLAQHLEDGPRRVKVSHAFLPRV 174
TA+ +V + TA+ AI L+E + S A+ + PR V+ + V
Sbjct: 65 TAASGVVRLKKTATAGAIS---ELTESRLRSGTGAFTTTKRTGIPAPREFSVTVSRERSV 121
Query: 175 PKVQSNGPVSICLEAGTWRSLEKATAAIQVPDDIYHSPSWEARESALSPDRSAEVSNSIH 234
P+ SN S+ ++ P +PS + ++ +++A S
Sbjct: 122 PRGPSNPRKSVS---------SPTSSNTPTPTKHLRTPSTKPKQENEGGEKAALESQVRE 172
Query: 235 PLDDTRPGDG---RRVTPLDSEKSTSCLNATSV---------ASHTPGTEELKPELLLPK 282
L + + D R + L K LNA S +PG E L K
Sbjct: 173 LLAEAKAKDSEINRLRSELKKYKEKRTLNAEGTDALGPNVDGTSVSPGDTEPMIRALEEK 232
Query: 283 DNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRASDCPSSSNNHQNLVSL 342
+ + K+L L +++ HS S+G+ S H G +S CP+S + S
Sbjct: 233 NKNFQKELSDLEEENRVLKEKLIYLEHSPNSEGAAS---HTGDSS-CPTSITQESSFGSP 288
Query: 343 KTNSASKSAPGCQEQTANN------------------PTESD----TLEFPNCP-GSNHL 379
N S ++ N P SD T E P+ P S
Sbjct: 289 TGNQMSSDIDEYKKNIHGNALRTSGSSSSDVTKASLSPDASDFEHITAETPSRPLSSTSN 348
Query: 380 PSSLSRSETKLQSNREISDINQIHLARGELCDLQGRLQSVEESLHSNQEKIKVLLNVIQD 439
P S+ T S +S+++ L L ++Q +EE+ HS E+++ L + D
Sbjct: 349 PFKSSKCSTAGSSPNSVSELS--------LASLTEKIQKMEENHHSTAEELQATLQELSD 400
Query: 440 LEK 442
++
Sbjct: 401 QQQ 403
>gi|75750466 spectrin domain with coiled-coils 1 NSP5b3a [Homo
sapiens]
Length = 790
Score = 40.4 bits (93), Expect = 0.004
Identities = 79/363 (21%), Positives = 133/363 (36%), Gaps = 60/363 (16%)
Query: 116 TASKSLVEMP-TASQSAIQVNGNLSEQDIVSSDLAYLRLAQHLEDGPRRVKVSHAFLPRV 174
TA+ +V + TA+ AI L+E + S A+ + PR V+ + V
Sbjct: 65 TAASGVVRLKKTATAGAIS---ELTESRLRSGTGAFTTTKRTGIPAPREFSVTVSRERSV 121
Query: 175 PKVQSNGPVSICLEAGTWRSLEKATAAIQVPDDIYHSPSWEARESALSPDRSAEVSNSIH 234
P+ SN S+ ++ P +PS + ++ +++A S
Sbjct: 122 PRGPSNPRKSVS---------SPTSSNTPTPTKHLRTPSTKPKQENEGGEKAALESQVRE 172
Query: 235 PLDDTRPGDG---RRVTPLDSEKSTSCLNATSV---------ASHTPGTEELKPELLLPK 282
L + + D R + L K LNA S +PG E L K
Sbjct: 173 LLAEAKAKDSEINRLRSELKKYKEKRTLNAEGTDALGPNVDGTSVSPGDTEPMIRALEEK 232
Query: 283 DNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRASDCPSSSNNHQNLVSL 342
+ + K+L L +++ HS S+G+ S H G +S CP+S + S
Sbjct: 233 NKNFQKELSDLEEENRVLKEKLIYLEHSPNSEGAAS---HTGDSS-CPTSITQESSFGSP 288
Query: 343 KTNSASKSAPGCQEQTANN------------------PTESD----TLEFPNCP-GSNHL 379
N S ++ N P SD T E P+ P S
Sbjct: 289 TGNQMSSDIDEYKKNIHGNALRTSGSSSSDVTKASLSPDASDFEHITAETPSRPLSSTSN 348
Query: 380 PSSLSRSETKLQSNREISDINQIHLARGELCDLQGRLQSVEESLHSNQEKIKVLLNVIQD 439
P S+ T S +S+++ L L ++Q +EE+ HS E+++ L + D
Sbjct: 349 PFKSSKCSTAGSSPNSVSELS--------LASLTEKIQKMEENHHSTAEELQATLQELSD 400
Query: 440 LEK 442
++
Sbjct: 401 QQQ 403
>gi|49472835 bridging integrator 2 [Homo sapiens]
Length = 565
Score = 38.1 bits (87), Expect = 0.020
Identities = 32/120 (26%), Positives = 49/120 (40%), Gaps = 7/120 (5%)
Query: 248 TPLDSEKSTSCLNATSVASHTPGTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPR 307
+PL S S S L+ S + TE+L P+ +DNS+ K+L KE
Sbjct: 273 SPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE-------G 325
Query: 308 THSSPSQGSHSQPAHPGRASDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDT 367
+ +S S+ PA G A PS + S++ +PG + P+ S T
Sbjct: 326 SEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSAT 385
>gi|157738639 tensin 4 [Homo sapiens]
Length = 715
Score = 37.7 bits (86), Expect = 0.027
Identities = 51/207 (24%), Positives = 76/207 (36%), Gaps = 46/207 (22%)
Query: 197 KATAAIQVPDDIYHSPSWEARESALSPDRSAEVSN-SIHPLDDTRPGDGRRVTPLDSEKS 255
KA++ + + SP E R L+P R + +S S P+ D G + L S S
Sbjct: 239 KASSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNS 298
Query: 256 TSCLNATSVASHTPGTEELKPELLLPKDNSDDKDLGSLS--SQSKETCVPSSPRTHSSPS 313
+ ++ S+ S + L LGS+S ++ + P +P
Sbjct: 299 SHQSSSRSLESPANSSSSLH-------------SLGSVSLCTRPSDFQAPRNPTLTMGQP 345
Query: 314 QGSHSQPAHPGRASDCPSSSNN--------------------------HQNLVSLKTNSA 347
+ HS P AS CP S N HQN S++ +A
Sbjct: 346 RTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEPGSSPPQRTPGHQN--SVQPGAA 403
Query: 348 SKSAPGCQEQTANNPTESDTLEFPNCP 374
S S P C +N+ T SD F CP
Sbjct: 404 SPSNP-CPATRSNSQTLSDA-PFTTCP 428
>gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo
sapiens]
Length = 987
Score = 37.7 bits (86), Expect = 0.027
Identities = 47/200 (23%), Positives = 77/200 (38%), Gaps = 35/200 (17%)
Query: 266 SHTPGTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGR 325
S +PG E L K+ + K+L L +++ HS S+G+ S H G
Sbjct: 135 SVSPGDTEPMIRALEEKNKNFQKELSDLEEENRVLKEKLIYLEHSPNSEGAAS---HTGD 191
Query: 326 ASDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANN------------------PTESD- 366
+S CP+S + S N S ++ N P SD
Sbjct: 192 SS-CPTSITQESSFGSPTGNQMSSDIDEYKKNIHGNALRTSGSSSSDVTKASLSPDASDF 250
Query: 367 ---TLEFPNCP-GSNHLPSSLSRSETKLQSNREISDINQIHLARGELCDLQGRLQSVEES 422
T E P+ P S P S+ T S +S+++ L L ++Q +EE+
Sbjct: 251 EHITAETPSRPLSSTSNPFKSSKCSTAGSSPNSVSELS--------LASLTEKIQKMEEN 302
Query: 423 LHSNQEKIKVLLNVIQDLEK 442
HS E+++ L + D ++
Sbjct: 303 HHSTAEELQATLQELSDQQQ 322
>gi|75750468 spectrin domain with coiled-coils 1 NSP5a3a [Homo
sapiens]
Length = 709
Score = 37.7 bits (86), Expect = 0.027
Identities = 47/200 (23%), Positives = 77/200 (38%), Gaps = 35/200 (17%)
Query: 266 SHTPGTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGR 325
S +PG E L K+ + K+L L +++ HS S+G+ S H G
Sbjct: 135 SVSPGDTEPMIRALEEKNKNFQKELSDLEEENRVLKEKLIYLEHSPNSEGAAS---HTGD 191
Query: 326 ASDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANN------------------PTESD- 366
+S CP+S + S N S ++ N P SD
Sbjct: 192 SS-CPTSITQESSFGSPTGNQMSSDIDEYKKNIHGNALRTSGSSSSDVTKASLSPDASDF 250
Query: 367 ---TLEFPNCP-GSNHLPSSLSRSETKLQSNREISDINQIHLARGELCDLQGRLQSVEES 422
T E P+ P S P S+ T S +S+++ L L ++Q +EE+
Sbjct: 251 EHITAETPSRPLSSTSNPFKSSKCSTAGSSPNSVSELS--------LASLTEKIQKMEEN 302
Query: 423 LHSNQEKIKVLLNVIQDLEK 442
HS E+++ L + D ++
Sbjct: 303 HHSTAEELQATLQELSDQQQ 322
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 37.7 bits (86), Expect = 0.027
Identities = 58/272 (21%), Positives = 102/272 (37%), Gaps = 31/272 (11%)
Query: 178 QSNGPVSICLEAGTWRSLEKATAAIQVPDDIYHSPSWEARESALSPDRSAEVSNSIHPLD 237
Q GP ++G +S +KA A ++ S S + S+ S S+ S + +
Sbjct: 2527 QEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEE 2586
Query: 238 DTRPGDG--------------RRVTPLDSEKSTSCLNATSVASHTPGTEELKPELLLPKD 283
+ GDG R +P S S+S +++S +S + +
Sbjct: 2587 GDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSS----SS 2642
Query: 284 NSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGSHSQPAHPGRASDCPSSSNNHQNLVSLK 343
+S S SS S + SS + SS + S + A+ P++ + Q + K
Sbjct: 2643 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTK 2702
Query: 344 -TNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPSSLSRSETKLQSNREISDINQI 402
T A K+ P +A++P + P P P+ + + + + +
Sbjct: 2703 ATKQAGKARP-----SAHSPGKKTPAPQPQAPPPQ--PTQPLQPKAQAGAKSRPKKREGV 2755
Query: 403 HLARGELCDLQGRLQSVEESLHSNQEKIKVLL 434
HL + + RL SVE N+ KI L
Sbjct: 2756 HLPTTKELAKRQRLPSVE-----NRPKIAAFL 2782
>gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1662
Score = 36.6 bits (83), Expect = 0.059
Identities = 45/204 (22%), Positives = 85/204 (41%), Gaps = 27/204 (13%)
Query: 220 ALSPDRSAEVSNSI-HPL-DDTRPGDGRRVTPLDSEKSTSCLNATSVAS---HTPGTEEL 274
ALSP S + + S+ P+ +D PG R + +TS L+ V+ + P L
Sbjct: 765 ALSPQLSEQKNLSLLSPVPEDKGPGHTRAGLEMSLRAATSSLSEEQVSELRDNLPKEVRL 824
Query: 275 KPELLLPKDNSDDKDLGSLSSQS---KETCVPSSPRTHSSPSQGSHSQPAHPGR------ 325
P+L+L +S + S + Q ++ V + + PS+G A GR
Sbjct: 825 SPKLILDPKSSVTPAIISAALQQVVHNKSLVTAGGALGNPPSRGERRLEASMGRPEVSMM 884
Query: 326 ------------ASDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNC 373
+ P +S N Q+ + + +S+ ++ G + + + + D+L N
Sbjct: 885 SSSASKNLKFKISPSAPETSWNSQHQLGAEVSSSPRAPTGSRADSLHLSQQEDSLPVQNF 944
Query: 374 PGSNHLPSSLSRSETKLQSNREIS 397
P ++L + SR Q+ E++
Sbjct: 945 PPKSYLLRT-SRESVGKQATGEVA 967
>gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1810
Score = 36.6 bits (83), Expect = 0.059
Identities = 45/204 (22%), Positives = 85/204 (41%), Gaps = 27/204 (13%)
Query: 220 ALSPDRSAEVSNSI-HPL-DDTRPGDGRRVTPLDSEKSTSCLNATSVAS---HTPGTEEL 274
ALSP S + + S+ P+ +D PG R + +TS L+ V+ + P L
Sbjct: 913 ALSPQLSEQKNLSLLSPVPEDKGPGHTRAGLEMSLRAATSSLSEEQVSELRDNLPKEVRL 972
Query: 275 KPELLLPKDNSDDKDLGSLSSQS---KETCVPSSPRTHSSPSQGSHSQPAHPGR------ 325
P+L+L +S + S + Q ++ V + + PS+G A GR
Sbjct: 973 SPKLILDPKSSVTPAIISAALQQVVHNKSLVTAGGALGNPPSRGERRLEASMGRPEVSMM 1032
Query: 326 ------------ASDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNC 373
+ P +S N Q+ + + +S+ ++ G + + + + D+L N
Sbjct: 1033 SSSASKNLKFKISPSAPETSWNSQHQLGAEVSSSPRAPTGSRADSLHLSQQEDSLPVQNF 1092
Query: 374 PGSNHLPSSLSRSETKLQSNREIS 397
P ++L + SR Q+ E++
Sbjct: 1093 PPKSYLLRT-SRESVGKQATGEVA 1115
>gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1810
Score = 36.6 bits (83), Expect = 0.059
Identities = 45/204 (22%), Positives = 85/204 (41%), Gaps = 27/204 (13%)
Query: 220 ALSPDRSAEVSNSI-HPL-DDTRPGDGRRVTPLDSEKSTSCLNATSVAS---HTPGTEEL 274
ALSP S + + S+ P+ +D PG R + +TS L+ V+ + P L
Sbjct: 913 ALSPQLSEQKNLSLLSPVPEDKGPGHTRAGLEMSLRAATSSLSEEQVSELRDNLPKEVRL 972
Query: 275 KPELLLPKDNSDDKDLGSLSSQS---KETCVPSSPRTHSSPSQGSHSQPAHPGR------ 325
P+L+L +S + S + Q ++ V + + PS+G A GR
Sbjct: 973 SPKLILDPKSSVTPAIISAALQQVVHNKSLVTAGGALGNPPSRGERRLEASMGRPEVSMM 1032
Query: 326 ------------ASDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNC 373
+ P +S N Q+ + + +S+ ++ G + + + + D+L N
Sbjct: 1033 SSSASKNLKFKISPSAPETSWNSQHQLGAEVSSSPRAPTGSRADSLHLSQQEDSLPVQNF 1092
Query: 374 PGSNHLPSSLSRSETKLQSNREIS 397
P ++L + SR Q+ E++
Sbjct: 1093 PPKSYLLRT-SRESVGKQATGEVA 1115
>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
sapiens]
Length = 1393
Score = 36.2 bits (82), Expect = 0.077
Identities = 37/168 (22%), Positives = 61/168 (36%), Gaps = 13/168 (7%)
Query: 205 PDDIYHSPSWEARESA-LSPDRSAE------VSNSIHPLDDTRPGDGRRVTPLDSEKST- 256
P + + W A E+ LSP E ++N L P + TP +EK+T
Sbjct: 857 PAEPTENREWTANENTTLSPAEPTEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKTTP 916
Query: 257 SCLNATSVASHTPGTEELKPELLLPKDNSDDKDLGSLSSQSKETCVPSSPRTHSSPSQGS 316
S T TP L E+ P ++ + G + K T P+ P H +
Sbjct: 917 SSAEPTEHGERTP----LANEITTPS-RAEPTEHGERIANEKATPSPAKPTEHGETTVNE 971
Query: 317 HSQPAHPGRASDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTE 364
+ P+ + + ++N + T S E+T +P E
Sbjct: 972 DTTPSSAEPTENGERTPLANENTTTSPTESTEHGERTANEKTTPSPAE 1019
>gi|229577185 epidermal growth factor receptor pathway substrate 15
isoform B [Homo sapiens]
Length = 582
Score = 36.2 bits (82), Expect = 0.077
Identities = 43/169 (25%), Positives = 67/169 (39%), Gaps = 11/169 (6%)
Query: 373 CPGSNHLPSSLSRSETKLQSNREISDINQIHLARGELCDLQGRLQSVEESLHSNQEKIKV 432
C L SSL T +S + ++ AR EL LQ +EES+ S + +++
Sbjct: 105 CAEEAQLISSLKAELTSQESQISTYE-EELAKAREELSRLQQETAELEESVESGKAQLEP 163
Query: 433 LLNVIQDLEK-----ARALTEGRNFYRTGQDLNNCST----CQNTACIIYSVEYDFRQQE 483
L +QD ++ L E ++ LN CS+ N A S+ +
Sbjct: 164 LQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNWCSSPHSILVNGATDYCSLSTSSSETA 223
Query: 484 G-RFHEVLQSLEEAEPVEEASPPPKSPAEPPAPEKQDLRRKTKKVKKKC 531
H QS E+EP+ + SP SP P+ + T +K C
Sbjct: 224 NLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDENEVTTAVTEKVC 272
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 36.2 bits (82), Expect = 0.077
Identities = 43/169 (25%), Positives = 67/169 (39%), Gaps = 11/169 (6%)
Query: 373 CPGSNHLPSSLSRSETKLQSNREISDINQIHLARGELCDLQGRLQSVEESLHSNQEKIKV 432
C L SSL T +S + ++ AR EL LQ +EES+ S + +++
Sbjct: 419 CAEEAQLISSLKAELTSQESQISTYE-EELAKAREELSRLQQETAELEESVESGKAQLEP 477
Query: 433 LLNVIQDLEK-----ARALTEGRNFYRTGQDLNNCST----CQNTACIIYSVEYDFRQQE 483
L +QD ++ L E ++ LN CS+ N A S+ +
Sbjct: 478 LQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNWCSSPHSILVNGATDYCSLSTSSSETA 537
Query: 484 G-RFHEVLQSLEEAEPVEEASPPPKSPAEPPAPEKQDLRRKTKKVKKKC 531
H QS E+EP+ + SP SP P+ + T +K C
Sbjct: 538 NLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDENEVTTAVTEKVC 586
Score = 31.6 bits (70), Expect = 1.9
Identities = 34/168 (20%), Positives = 62/168 (36%), Gaps = 32/168 (19%)
Query: 395 EISDINQIHLARGELCDLQGRLQSVEESLHSNQEKIKVLLNVIQDL--EKARALTEGRNF 452
+ S I ++ E+ DLQ +VE+ L ++ IK + +QDL E R T +
Sbjct: 328 DFSAIKELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKL 387
Query: 453 YRTGQDLNNC-------------------STCQNTACIIYSVEYDFRQQEGRF------- 486
Q + C A +I S++ + QE +
Sbjct: 388 QAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEEL 447
Query: 487 ----HEVLQSLEEAEPVEEASPPPKSPAEPPAPEKQDLRRKTKKVKKK 530
E+ + +E +EE+ K+ EP QD +++ ++ K
Sbjct: 448 AKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMK 495
>gi|46195763 metastasis suppressor 1-like [Homo sapiens]
Length = 747
Score = 36.2 bits (82), Expect = 0.077
Identities = 40/150 (26%), Positives = 61/150 (40%), Gaps = 30/150 (20%)
Query: 200 AAIQVPDDIYHSP-SWEARESALSPDRSAEVSNSIHPLDDTR----------PGDGRRVT 248
A+ QV D+ S SW + SP S+ +S+ + PG + +
Sbjct: 241 ASEQVIKDLKGSDYSWSYQTPPSSPSSSSSRKSSMCSAPSSSSSAKGGGAPWPGGAQTYS 300
Query: 249 PLDS-------EKSTSCLNATSVASHTPG-----TEELKPELLLPKDNSDDKDLGSLSSQ 296
P + + +T+ +SV+SH G KP +P D + K S SS+
Sbjct: 301 PSSTCRYRSLAQPATTTARLSSVSSHDSGFVSQDATYSKPPSPMPSDITSQKSSSSASSE 360
Query: 297 SKETCVPSSPRTHSSPSQ-----GSHSQPA 321
+ ETC S SSP+ GSH QP+
Sbjct: 361 ASETC--QSVSECSSPTSDWSKVGSHEQPS 388
Score = 29.3 bits (64), Expect = 9.4
Identities = 38/172 (22%), Positives = 71/172 (41%), Gaps = 16/172 (9%)
Query: 275 KPELLLPKDNSDDKDL-GSLSSQSKETCVPSSPRTHSS--------PSQGSHSQ----PA 321
+P L P KDL GS S S +T PSSP + SS PS S ++ P
Sbjct: 234 EPHKLPPASEQVIKDLKGSDYSWSYQT-PPSSPSSSSSRKSSMCSAPSSSSSAKGGGAPW 292
Query: 322 HPGRASDCPSSSNNHQNLVSLKTNSASKSAPGCQEQTANNPTESDTLEFPNCPGSNHLPS 381
G + PSS+ +++L T +A S+ + + ++ T P P + + S
Sbjct: 293 PGGAQTYSPSSTCRYRSLAQPATTTARLSSVSSHD--SGFVSQDATYSKPPSPMPSDITS 350
Query: 382 SLSRSETKLQSNREISDINQIHLARGELCDLQGRLQSVEESLHSNQEKIKVL 433
S S +++ +++ + + Q +L ++++++L
Sbjct: 351 QKSSSSASSEASETCQSVSECSSPTSDWSKVGSHEQPSGATLQRRKDRVELL 402
>gi|42518068 trans-golgi network protein 2 [Homo sapiens]
Length = 437
Score = 35.8 bits (81), Expect = 0.10
Identities = 44/186 (23%), Positives = 78/186 (41%), Gaps = 17/186 (9%)
Query: 194 SLEKATAAIQVPDDIYHSPSWEARESALSPDRSAEVSNSIHPLDDTRPGDGRRVTPLD-S 252
S K+ A Q P+D + EA+ SP +S + + + + DG+ TP D S
Sbjct: 136 STGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQ--TPKDGS 193
Query: 253 EKSTSCLNATSVASHTPGTEELKPELLLPKDNSDDKDL--GSLSSQSKETCVPSSPR--T 308
KS + + G E+ P+ K ++++ G S ++E SP
Sbjct: 194 SKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVV 253
Query: 309 HSSPSQGSHSQP-AHPGRASDCPSSSNNH------QNLVSLKTNSASKS---APGCQEQT 358
PS+ HS+P ++P + P + N + + KT S ++ +P +E
Sbjct: 254 PEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVK 313
Query: 359 ANNPTE 364
++ PTE
Sbjct: 314 SSEPTE 319
>gi|216547801 SH2 domain containing 3C isoform e [Homo sapiens]
Length = 700
Score = 35.8 bits (81), Expect = 0.10
Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 1/41 (2%)
Query: 295 SQSKETCVPSSPRTHSSPSQGSHSQPAHP-GRASDCPSSSN 334
S + C S+P+TH +G H+ P+H G+AS PS S+
Sbjct: 286 SSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPSLSS 326
>gi|216547790 SH2 domain containing 3C isoform d [Homo sapiens]
Length = 702
Score = 35.8 bits (81), Expect = 0.10
Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 1/41 (2%)
Query: 295 SQSKETCVPSSPRTHSSPSQGSHSQPAHP-GRASDCPSSSN 334
S + C S+P+TH +G H+ P+H G+AS PS S+
Sbjct: 288 SSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPSLSS 328
>gi|216547779 SH2 domain containing 3C isoform c [Homo sapiens]
Length = 506
Score = 35.8 bits (81), Expect = 0.10
Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 1/41 (2%)
Query: 295 SQSKETCVPSSPRTHSSPSQGSHSQPAHP-GRASDCPSSSN 334
S + C S+P+TH +G H+ P+H G+AS PS S+
Sbjct: 92 SSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPSLSS 132
>gi|216547769 SH2 domain containing 3C isoform c [Homo sapiens]
Length = 506
Score = 35.8 bits (81), Expect = 0.10
Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 1/41 (2%)
Query: 295 SQSKETCVPSSPRTHSSPSQGSHSQPAHP-GRASDCPSSSN 334
S + C S+P+TH +G H+ P+H G+AS PS S+
Sbjct: 92 SSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPSLSS 132
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.125 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,781,598
Number of Sequences: 37866
Number of extensions: 1127605
Number of successful extensions: 7661
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 214
Number of HSP's that attempted gapping in prelim test: 7073
Number of HSP's gapped (non-prelim): 749
length of query: 535
length of database: 18,247,518
effective HSP length: 107
effective length of query: 428
effective length of database: 14,195,856
effective search space: 6075826368
effective search space used: 6075826368
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.