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Search of human proteins with 193083114
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|193083114 poly(rC) binding protein 2 isoform g [Homo
sapiens]
(318 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 621 e-178
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 612 e-175
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] 606 e-173
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 595 e-170
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 594 e-170
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 590 e-169
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 588 e-168
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 498 e-141
gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 495 e-140
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 441 e-124
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] 370 e-102
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] 370 e-102
gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens] 286 2e-77
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ... 106 2e-23
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ... 106 2e-23
gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ... 106 2e-23
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ... 87 3e-17
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ... 87 3e-17
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ... 79 5e-15
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ... 77 2e-14
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 77 2e-14
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 77 2e-14
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 74 2e-13
gi|17402900 far upstream element-binding protein [Homo sapiens] 73 3e-13
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ... 73 4e-13
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 73 4e-13
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1... 70 2e-12
gi|122937472 bicaudal C homolog 1 [Homo sapiens] 64 1e-10
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 55 8e-08
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 55 8e-08
>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
Length = 318
Score = 621 bits (1601), Expect = e-178
Identities = 318/318 (100%), Positives = 318/318 (100%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
Query: 181 KPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDASAQT 240
KPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDASAQT
Sbjct: 181 KPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDASAQT 240
Query: 241 TSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLA 300
TSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLA
Sbjct: 241 TSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLA 300
Query: 301 QYLINVRLSSETGGMGSS 318
QYLINVRLSSETGGMGSS
Sbjct: 301 QYLINVRLSSETGGMGSS 318
>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
Length = 331
Score = 612 bits (1577), Expect = e-175
Identities = 318/331 (96%), Positives = 318/331 (96%), Gaps = 13/331 (3%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
Query: 181 KPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFS--------- 231
KPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFS
Sbjct: 181 KPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEV 240
Query: 232 ----AGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQ 287
AGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQ
Sbjct: 241 KGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQ 300
Query: 288 VTITGSAASISLAQYLINVRLSSETGGMGSS 318
VTITGSAASISLAQYLINVRLSSETGGMGSS
Sbjct: 301 VTITGSAASISLAQYLINVRLSSETGGMGSS 331
>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
Length = 335
Score = 606 bits (1562), Expect = e-173
Identities = 318/335 (94%), Positives = 318/335 (94%), Gaps = 17/335 (5%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE----SPPKGVTI 176
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE SPPKGVTI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
Query: 177 PYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFS----- 231
PYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFS
Sbjct: 181 PYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESS 240
Query: 232 --------AGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS 283
AGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS
Sbjct: 241 SPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS 300
Query: 284 TDRQVTITGSAASISLAQYLINVRLSSETGGMGSS 318
TDRQVTITGSAASISLAQYLINVRLSSETGGMGSS
Sbjct: 301 TDRQVTITGSAASISLAQYLINVRLSSETGGMGSS 335
>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
Length = 362
Score = 595 bits (1535), Expect = e-170
Identities = 318/362 (87%), Positives = 318/362 (87%), Gaps = 44/362 (12%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
Query: 181 KPSSSPVIFAGGQ-------------------------------AYTIQGQYAIPQPDLT 209
KPSSSPVIFAGGQ AYTIQGQYAIPQPDLT
Sbjct: 181 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 240
Query: 210 KLHQLAMQQSHFPMTHGNTGFS-------------AGLDASAQTTSHELTIPNDLIGCII 256
KLHQLAMQQSHFPMTHGNTGFS AGLDASAQTTSHELTIPNDLIGCII
Sbjct: 241 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCII 300
Query: 257 GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG 316
GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG
Sbjct: 301 GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG 360
Query: 317 SS 318
SS
Sbjct: 361 SS 362
>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
Length = 361
Score = 594 bits (1532), Expect = e-170
Identities = 317/361 (87%), Positives = 317/361 (87%), Gaps = 43/361 (11%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
Query: 181 KPSSSPVIFAGGQ-------------------------------AYTIQGQYAIPQPDLT 209
KPSSSPVIFAGGQ AYTIQGQYAIPQPDLT
Sbjct: 181 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 240
Query: 210 KLHQLAMQQSHFPMTHGNTGFSA------------GLDASAQTTSHELTIPNDLIGCIIG 257
KLHQLAMQQSHFPMTHGNTGFS GLDASAQTTSHELTIPNDLIGCIIG
Sbjct: 241 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIG 300
Query: 258 RQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGS 317
RQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGS
Sbjct: 301 RQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGS 360
Query: 318 S 318
S
Sbjct: 361 S 361
>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 590 bits (1520), Expect = e-169
Identities = 318/366 (86%), Positives = 318/366 (86%), Gaps = 48/366 (13%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE----SPPKGVTI 176
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE SPPKGVTI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
Query: 177 PYRPKPSSSPVIFAGGQ-------------------------------AYTIQGQYAIPQ 205
PYRPKPSSSPVIFAGGQ AYTIQGQYAIPQ
Sbjct: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
Query: 206 PDLTKLHQLAMQQSHFPMTHGNTGFS-------------AGLDASAQTTSHELTIPNDLI 252
PDLTKLHQLAMQQSHFPMTHGNTGFS AGLDASAQTTSHELTIPNDLI
Sbjct: 241 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLI 300
Query: 253 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 312
GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET
Sbjct: 301 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 360
Query: 313 GGMGSS 318
GGMGSS
Sbjct: 361 GGMGSS 366
>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
Length = 365
Score = 588 bits (1517), Expect = e-168
Identities = 317/365 (86%), Positives = 317/365 (86%), Gaps = 47/365 (12%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE----SPPKGVTI 176
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE SPPKGVTI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
Query: 177 PYRPKPSSSPVIFAGGQ-------------------------------AYTIQGQYAIPQ 205
PYRPKPSSSPVIFAGGQ AYTIQGQYAIPQ
Sbjct: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
Query: 206 PDLTKLHQLAMQQSHFPMTHGNTGFSA------------GLDASAQTTSHELTIPNDLIG 253
PDLTKLHQLAMQQSHFPMTHGNTGFS GLDASAQTTSHELTIPNDLIG
Sbjct: 241 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIG 300
Query: 254 CIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETG 313
CIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETG
Sbjct: 301 CIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETG 360
Query: 314 GMGSS 318
GMGSS
Sbjct: 361 GMGSS 365
>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
Length = 371
Score = 498 bits (1281), Expect = e-141
Identities = 261/339 (76%), Positives = 287/339 (84%), Gaps = 23/339 (6%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 33 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
+ GPT+AIFKAFAMI K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 93 ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLESPPKG TIPYRP
Sbjct: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRP 212
Query: 181 KPSSSPVIFAGGQAYTIQGQYAIPQPD-LTKLHQLAMQQSHFPMTHGNT----------- 228
KP+S+PVIFAGGQAYTIQGQYAIP PD LTKLHQLAMQQ+ FP G T
Sbjct: 213 KPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPL-GQTNPAFPGEKLPL 271
Query: 229 ----------GFSAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIAN 278
G S+GLDAS ++HELTIPNDLIGCIIGRQG KINEIRQMSGAQIKIAN
Sbjct: 272 HSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIAN 331
Query: 279 PVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGS 317
EGS++RQ+TITG+ A+ISLAQYLIN RL+SE GMG+
Sbjct: 332 ATEGSSERQITITGTPANISLAQYLINARLTSEVTGMGT 370
>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
Length = 356
Score = 495 bits (1274), Expect = e-140
Identities = 273/358 (76%), Positives = 292/358 (81%), Gaps = 42/358 (11%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MD GV E GLNVTLTIRLLMHGKEVGSIIGKKGESVK++REESGARINISEGNCPERIIT
Sbjct: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
L GPTNAIFKAFAMIIDKLEEDI+SSMTNSTAASRPPVTLRLVVPA+QCGSLIGKGGCKI
Sbjct: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLES---PPKG--VT 175
KEIRESTGAQVQVAGDMLPNSTERAITIAG+PQS+ ECVKQIC+VMLE+ P+G +T
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180
Query: 176 IPYRPKPSSSPVIFAGGQ----------------------AYTIQGQYAIPQPDLTKLHQ 213
IPY+P P+SSPVI AGGQ AY+IQGQ+ I DL KL+Q
Sbjct: 181 IPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQ 240
Query: 214 LAMQQSHFPMTHGNTGFS-------------AGLDASAQTTSHELTIPNDLIGCIIGRQG 260
+A QQSHF M HG TGF+ A LDAS QTT HELTIPN+LIGCIIGRQG
Sbjct: 241 VARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTT-HELTIPNNLIGCIIGRQG 299
Query: 261 AKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGSS 318
A INEIRQMSGAQIKIANPVEGS+ RQVTITGSAASISLAQYLIN RLSSE GMG S
Sbjct: 300 ANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSEK-GMGCS 356
>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
Length = 345
Score = 441 bits (1133), Expect = e-124
Identities = 239/338 (70%), Positives = 263/338 (77%), Gaps = 47/338 (13%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 33 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
+ GPT+AIFKAFAMI K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 93 ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLE
Sbjct: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLE------------ 200
Query: 181 KPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNT------------ 228
AYTIQGQYAIP PDLTKLHQLAMQQ+ FP G T
Sbjct: 201 -------------AYTIQGQYAIPHPDLTKLHQLAMQQTPFPPL-GQTNPAFPGEKLPLH 246
Query: 229 ---------GFSAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP 279
G S+GLDAS ++HELTIPNDLIGCIIGRQG KINEIRQMSGAQIKIAN
Sbjct: 247 SSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANA 306
Query: 280 VEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGS 317
EGS++RQ+TITG+ A+ISLAQYLIN RL+SE GMG+
Sbjct: 307 TEGSSERQITITGTPANISLAQYLINARLTSEVTGMGT 344
>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 370 bits (949), Expect = e-102
Identities = 192/316 (60%), Positives = 236/316 (74%), Gaps = 8/316 (2%)
Query: 7 EGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTN 66
E L++TLT+R+LMHGKEVGSIIGKKGE+VK++RE+S ARI ISEG+CPERI T+ G T
Sbjct: 11 EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70
Query: 67 AIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
A+F A +MI KL+ED+ ++ N SRPPVTLRLV+PASQCGSLIGK G KIKEIRE+
Sbjct: 71 AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130
Query: 127 TGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSP 186
TGAQVQVAGD+LPNSTERA+T++G+P +II CV+QIC V+LESPPKG TIPY P S
Sbjct: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGT 190
Query: 187 VIFAGGQAYTIQGQY-AIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDASAQTTSHEL 245
V+ + Q +++QGQY A+ ++TKL QL+ F GLD QT+S E
Sbjct: 191 VLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPF----ATPSVVPGLDPGTQTSSQEF 246
Query: 246 TIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLIN 305
+PNDLIGC+IGRQG+KI+EIRQMSGA IKI N EG+ +R VTITGS SI+LAQYLI
Sbjct: 247 LVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLIT 306
Query: 306 VRL---SSETGGMGSS 318
L S +GG SS
Sbjct: 307 ACLETAKSTSGGTPSS 322
>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 370 bits (949), Expect = e-102
Identities = 192/316 (60%), Positives = 236/316 (74%), Gaps = 8/316 (2%)
Query: 7 EGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTN 66
E L++TLT+R+LMHGKEVGSIIGKKGE+VK++RE+S ARI ISEG+CPERI T+ G T
Sbjct: 11 EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70
Query: 67 AIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
A+F A +MI KL+ED+ ++ N SRPPVTLRLV+PASQCGSLIGK G KIKEIRE+
Sbjct: 71 AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130
Query: 127 TGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSP 186
TGAQVQVAGD+LPNSTERA+T++G+P +II CV+QIC V+LESPPKG TIPY P S
Sbjct: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGT 190
Query: 187 VIFAGGQAYTIQGQY-AIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDASAQTTSHEL 245
V+ + Q +++QGQY A+ ++TKL QL+ F GLD QT+S E
Sbjct: 191 VLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPF----ATPSVVPGLDPGTQTSSQEF 246
Query: 246 TIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLIN 305
+PNDLIGC+IGRQG+KI+EIRQMSGA IKI N EG+ +R VTITGS SI+LAQYLI
Sbjct: 247 LVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLIT 306
Query: 306 VRL---SSETGGMGSS 318
L S +GG SS
Sbjct: 307 ACLETAKSTSGGTPSS 322
>gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens]
Length = 424
Score = 286 bits (731), Expect = 2e-77
Identities = 164/336 (48%), Positives = 203/336 (60%), Gaps = 63/336 (18%)
Query: 42 ESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLR 101
+S ARI ISEG+CPERI T+ G T A+F A +MI KL+ED+ ++ N SRPPVTLR
Sbjct: 12 QSSARITISEGSCPERITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLR 71
Query: 102 LVVPASQCGSLIGKGGCKIK---EIR---------------------------------- 124
LV+PASQCGSLIGK G KIK E+R
Sbjct: 72 LVIPASQCGSLIGKAGTKIKEIREVRGEIYHPQGIRGKGAVVRGVLGLWRPPHLESSEPG 131
Query: 125 ------------------ESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVM 166
++TGAQVQVAGD+LPNSTERA+T++G+P +II CV+QIC V+
Sbjct: 132 QPFSGLWEQPEVAPVLCLQTTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVI 191
Query: 167 LESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQY-AIPQPDLTKLHQLAMQQSHFPMTH 225
LESPPKG TIPY P S V+ + Q +++QGQY A+ ++TKL QL+ F
Sbjct: 192 LESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPF---- 247
Query: 226 GNTGFSAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTD 285
GLD QT+S E +PNDLIGC+IGRQG+KI+EIRQMSGA IKI N EG+ +
Sbjct: 248 ATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGE 307
Query: 286 RQVTITGSAASISLAQYLINVRL---SSETGGMGSS 318
R VTITGS SI+LAQYLI L S +GG SS
Sbjct: 308 RHVTITGSPVSIALAQYLITACLETAKSTSGGTPSS 343
Score = 45.1 bits (105), Expect = 9e-05
Identities = 33/107 (30%), Positives = 49/107 (45%), Gaps = 13/107 (12%)
Query: 103 VVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSI------- 155
+VP G +IG+ G KI EIR+ +GA +++ G+ + ER +TI G P SI
Sbjct: 268 LVPNDLIGCVIGRQGSKISEIRQMSGAHIKI-GNQAEGAGERHVTITGSPVSIALAQYLI 326
Query: 156 ---IECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAG--GQAYTI 197
+E K S P + P+ P ++ P G G Y I
Sbjct: 327 TACLETAKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGTPYAI 373
Score = 35.4 bits (80), Expect = 0.067
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 11/97 (11%)
Query: 25 VGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAIFKAFAMIIDKLEE 81
+G +IG++G + ++R+ SGA I I +EG ER +T+ G +I A +I LE
Sbjct: 274 IGCVIGRQGSKISEIRQMSGAHIKIGNQAEG-AGERHVTITGSPVSIALAQYLITACLET 332
Query: 82 DISSSMTNSTAAS-------RPPVTLRLVVPASQCGS 111
S+S ++A PP+T P G+
Sbjct: 333 AKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGT 369
>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 106 bits (265), Expect = 2e-23
Identities = 59/185 (31%), Positives = 101/185 (54%), Gaps = 22/185 (11%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75
+R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I
Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
Query: 76 IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115
I LEE + + + TA S+ P+ LRL++ S G +IG
Sbjct: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
Query: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVT 175
G KIKE+RE+T +++ + P+ST+R + I G P ++EC+K I ++ ESP KG
Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222
Query: 176 IPYRP 180
PY P
Sbjct: 223 QPYDP 227
Score = 68.9 bits (167), Expect = 6e-12
Identities = 35/70 (50%), Positives = 45/70 (64%)
Query: 235 DASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSA 294
D + ++TIP DL G IIG+ G +I +IR SGA IKI P+EGS DR +TITG+
Sbjct: 382 DLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQ 441
Query: 295 ASISLAQYLI 304
I AQYL+
Sbjct: 442 DQIQNAQYLL 451
Score = 49.3 bits (116), Expect = 5e-06
Identities = 24/60 (40%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 96 PPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSI 155
P +T ++ +P GS+IGKGG +IK+IR +GA +++ + L S +R ITI G I
Sbjct: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444
Score = 48.5 bits (114), Expect = 8e-06
Identities = 53/196 (27%), Positives = 81/196 (41%), Gaps = 42/196 (21%)
Query: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
V LR+++ + G++IGKGG IK +R A V V P ER ++I+ ++I E
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
Query: 158 CVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQ 217
+K+I IP T++ +P P T QL ++
Sbjct: 100 ILKKI-------------IP------------------TLEEGLQLPSPTATS--QLPLE 126
Query: 218 QSHFPMTHGNTGFSAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIA 277
+ + D + H+ L G IIG +GAKI E+R+ + IK+
Sbjct: 127 SDAVECLNYQHYKGSDFDCELRLLIHQ-----SLAGGIIGVKGAKIKELRENTQTTIKLF 181
Query: 278 NP-VEGSTDRQVTITG 292
STDR V I G
Sbjct: 182 QECCPHSTDRVVLIGG 197
Score = 46.2 bits (108), Expect = 4e-05
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65
G + +RLL+H G IIG KG +K++RE + I + + CP +R++ + G
Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
Query: 66 NAIFKAFAMIIDKLEE 81
+ + + +I+D + E
Sbjct: 200 DRVVECIKIILDLISE 215
Score = 41.2 bits (95), Expect = 0.001
Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Query: 26 GSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEE 81
GSIIGK G+ +K++R ESGA I I E +RIIT+ G + I A ++ + +++
Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
[Homo sapiens]
Length = 463
Score = 106 bits (265), Expect = 2e-23
Identities = 59/185 (31%), Positives = 101/185 (54%), Gaps = 22/185 (11%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75
+R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I
Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
Query: 76 IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115
I LEE + + + TA S+ P+ LRL++ S G +IG
Sbjct: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
Query: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVT 175
G KIKE+RE+T +++ + P+ST+R + I G P ++EC+K I ++ ESP KG
Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222
Query: 176 IPYRP 180
PY P
Sbjct: 223 QPYDP 227
Score = 69.7 bits (169), Expect = 3e-12
Identities = 36/79 (45%), Positives = 48/79 (60%)
Query: 235 DASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSA 294
D + ++TIP DL G IIG+ G +I +IR SGA IKI P+EGS DR +TITG+
Sbjct: 382 DLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQ 441
Query: 295 ASISLAQYLINVRLSSETG 313
I AQYL+ + +G
Sbjct: 442 DQIQNAQYLLQNSVKQYSG 460
Score = 49.3 bits (116), Expect = 5e-06
Identities = 24/60 (40%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 96 PPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSI 155
P +T ++ +P GS+IGKGG +IK+IR +GA +++ + L S +R ITI G I
Sbjct: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444
Score = 48.5 bits (114), Expect = 8e-06
Identities = 53/196 (27%), Positives = 81/196 (41%), Gaps = 42/196 (21%)
Query: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
V LR+++ + G++IGKGG IK +R A V V P ER ++I+ ++I E
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
Query: 158 CVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQ 217
+K+I IP T++ +P P T QL ++
Sbjct: 100 ILKKI-------------IP------------------TLEEGLQLPSPTATS--QLPLE 126
Query: 218 QSHFPMTHGNTGFSAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIA 277
+ + D + H+ L G IIG +GAKI E+R+ + IK+
Sbjct: 127 SDAVECLNYQHYKGSDFDCELRLLIHQ-----SLAGGIIGVKGAKIKELRENTQTTIKLF 181
Query: 278 NP-VEGSTDRQVTITG 292
STDR V I G
Sbjct: 182 QECCPHSTDRVVLIGG 197
Score = 46.2 bits (108), Expect = 4e-05
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65
G + +RLL+H G IIG KG +K++RE + I + + CP +R++ + G
Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
Query: 66 NAIFKAFAMIIDKLEE 81
+ + + +I+D + E
Sbjct: 200 DRVVECIKIILDLISE 215
Score = 41.2 bits (95), Expect = 0.001
Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Query: 26 GSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEE 81
GSIIGK G+ +K++R ESGA I I E +RIIT+ G + I A ++ + +++
Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
>gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 106 bits (265), Expect = 2e-23
Identities = 59/185 (31%), Positives = 101/185 (54%), Gaps = 22/185 (11%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75
+R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I
Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
Query: 76 IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115
I LEE + + + TA S+ P+ LRL++ S G +IG
Sbjct: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
Query: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVT 175
G KIKE+RE+T +++ + P+ST+R + I G P ++EC+K I ++ ESP KG
Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222
Query: 176 IPYRP 180
PY P
Sbjct: 223 QPYDP 227
Score = 68.9 bits (167), Expect = 6e-12
Identities = 35/70 (50%), Positives = 45/70 (64%)
Query: 235 DASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSA 294
D + ++TIP DL G IIG+ G +I +IR SGA IKI P+EGS DR +TITG+
Sbjct: 382 DLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQ 441
Query: 295 ASISLAQYLI 304
I AQYL+
Sbjct: 442 DQIQNAQYLL 451
Score = 49.3 bits (116), Expect = 5e-06
Identities = 24/60 (40%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 96 PPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSI 155
P +T ++ +P GS+IGKGG +IK+IR +GA +++ + L S +R ITI G I
Sbjct: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444
Score = 48.5 bits (114), Expect = 8e-06
Identities = 53/196 (27%), Positives = 81/196 (41%), Gaps = 42/196 (21%)
Query: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
V LR+++ + G++IGKGG IK +R A V V P ER ++I+ ++I E
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
Query: 158 CVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQ 217
+K+I IP T++ +P P T QL ++
Sbjct: 100 ILKKI-------------IP------------------TLEEGLQLPSPTATS--QLPLE 126
Query: 218 QSHFPMTHGNTGFSAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIA 277
+ + D + H+ L G IIG +GAKI E+R+ + IK+
Sbjct: 127 SDAVECLNYQHYKGSDFDCELRLLIHQ-----SLAGGIIGVKGAKIKELRENTQTTIKLF 181
Query: 278 NP-VEGSTDRQVTITG 292
STDR V I G
Sbjct: 182 QECCPHSTDRVVLIGG 197
Score = 46.2 bits (108), Expect = 4e-05
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65
G + +RLL+H G IIG KG +K++RE + I + + CP +R++ + G
Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
Query: 66 NAIFKAFAMIIDKLEE 81
+ + + +I+D + E
Sbjct: 200 DRVVECIKIILDLISE 215
Score = 41.2 bits (95), Expect = 0.001
Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Query: 26 GSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEE 81
GSIIGK G+ +K++R ESGA I I E +RIIT+ G + I A ++ + +++
Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
sapiens]
Length = 507
Score = 86.7 bits (213), Expect = 3e-17
Identities = 80/329 (24%), Positives = 143/329 (43%), Gaps = 36/329 (10%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKA 71
+++++ G IIGK G +VK + E+SGA + +S+ N ER++T++G KA
Sbjct: 174 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 233
Query: 72 FAMIIDKLEED-------------ISSSMTNSTAASRPPVTLRLVVP-ASQCGSLIGKGG 117
+II K++ED ++ + NS P V+P A+ L+G
Sbjct: 234 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 293
Query: 118 CKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIP 177
+ + G+ L T T+A ++ +
Sbjct: 294 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 351
Query: 178 YRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDAS 237
P +++ ++ + G A L LA + T+G G ++ L AS
Sbjct: 352 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATA---ATNGYFGAASPLAAS 408
Query: 238 AQTTSH----------ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP---VEGST 284
A + E+ +P +L+G I+G+ G + E ++++GA+I+I+ V G+
Sbjct: 409 AILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTR 468
Query: 285 DRQVTITGSAASISLAQYLINVRLSSETG 313
+R+VTITG+ A+ AQYLI R++ E G
Sbjct: 469 NRKVTITGTPAATQAAQYLITQRITYEQG 497
Score = 70.9 bits (172), Expect = 1e-12
Identities = 52/198 (26%), Positives = 94/198 (47%), Gaps = 41/198 (20%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG-----NCPERIITLAGPTNAIFK 70
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 71 AFAMIIDKLEE---------------------------DISSSMTNSTAASRPPVT---- 99
I +K+ E + SS T + ++ P+T
Sbjct: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRA 171
Query: 100 --LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVA--GDMLPNSTERAITIAGIPQSI 155
++++VP S G +IGKGG +K + E +GA VQ++ D + N ER +T++G P+
Sbjct: 172 NQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGI-NLQERVVTVSGEPEQN 230
Query: 156 IECVKQICVVMLESPPKG 173
+ V+ I + E P G
Sbjct: 231 RKAVELIIQKIQEDPQSG 248
Score = 32.0 bits (71), Expect = 0.75
Identities = 17/58 (29%), Positives = 35/58 (60%), Gaps = 3/58 (5%)
Query: 244 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASIS 298
++ IP+ G IIG+ G I ++++ +GA IK++ + G+T+R I G+ +++
Sbjct: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALN 110
>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
sapiens]
Length = 483
Score = 86.7 bits (213), Expect = 3e-17
Identities = 80/329 (24%), Positives = 143/329 (43%), Gaps = 36/329 (10%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKA 71
+++++ G IIGK G +VK + E+SGA + +S+ N ER++T++G KA
Sbjct: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
Query: 72 FAMIIDKLEED-------------ISSSMTNSTAASRPPVTLRLVVP-ASQCGSLIGKGG 117
+II K++ED ++ + NS P V+P A+ L+G
Sbjct: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269
Query: 118 CKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIP 177
+ + G+ L T T+A ++ +
Sbjct: 270 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 327
Query: 178 YRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDAS 237
P +++ ++ + G A L LA + T+G G ++ L AS
Sbjct: 328 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATA---ATNGYFGAASPLAAS 384
Query: 238 AQTTSH----------ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP---VEGST 284
A + E+ +P +L+G I+G+ G + E ++++GA+I+I+ V G+
Sbjct: 385 AILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTR 444
Query: 285 DRQVTITGSAASISLAQYLINVRLSSETG 313
+R+VTITG+ A+ AQYLI R++ E G
Sbjct: 445 NRKVTITGTPAATQAAQYLITQRITYEQG 473
Score = 74.7 bits (182), Expect = 1e-13
Identities = 50/174 (28%), Positives = 91/174 (52%), Gaps = 17/174 (9%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 71 AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121
I +K+ E + + T + +P T+ +++VP S G +IGKGG +K
Sbjct: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
Query: 122 EIRESTGAQVQVA--GDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKG 173
+ E +GA VQ++ D + N ER +T++G P+ + V+ I + E P G
Sbjct: 172 AVMEQSGAWVQLSQKPDGI-NLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSG 224
Score = 32.0 bits (71), Expect = 0.75
Identities = 17/58 (29%), Positives = 35/58 (60%), Gaps = 3/58 (5%)
Query: 244 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASIS 298
++ IP+ G IIG+ G I ++++ +GA IK++ + G+T+R I G+ +++
Sbjct: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALN 110
>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
isoform a [Homo sapiens]
Length = 599
Score = 79.0 bits (193), Expect = 5e-15
Identities = 79/317 (24%), Positives = 142/317 (44%), Gaps = 26/317 (8%)
Query: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
Query: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
+A MI++ ++++ + + L+++ G LIGK G +K+I TG
Sbjct: 252 SEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETG 305
Query: 129 AQVQVAG--DMLPNSTERAITIAGIPQSI----IECVKQICVV----MLESPPKGVTIPY 178
++ ++ D+ + ER IT+ G ++ IE +K++ ML + IP
Sbjct: 306 TKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIP- 364
Query: 179 RPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFP--MTHGNTGFSAGLDA 236
S+ IF+ G + P H +F H G +
Sbjct: 365 -GLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHS 423
Query: 237 SAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITGSA 294
+ L IP +G IIG++GA I ++ + +GA IKIA P EG ++R V ITG
Sbjct: 424 YPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGPP 482
Query: 295 ASISLAQYLINVRLSSE 311
+ AQ I +L E
Sbjct: 483 EAQFKAQGRIFGKLKEE 499
Score = 73.9 bits (180), Expect = 2e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 490 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 544
Query: 133 VAGDMLPNSTERAI 146
V D P+ E I
Sbjct: 545 VPRDQTPDENEEVI 558
>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
isoform 1 [Homo sapiens]
Length = 577
Score = 77.4 bits (189), Expect = 2e-14
Identities = 72/309 (23%), Positives = 137/309 (44%), Gaps = 34/309 (11%)
Query: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
V + +RLL+ + VG+IIGK+G +++ + +++ ++I++ E+ I++
Sbjct: 194 VDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGC 253
Query: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
A MI++ + ++ + T V L+++ + G LIGK G +K++ + T
Sbjct: 254 SSACKMILEIMHKEAKDTKTADE------VPLKILAHNNFVGRLIGKEGRNLKKVEQDTE 307
Query: 129 AQVQVAG--DMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSP 186
++ ++ D+ + ER IT+ G ++ ++I + E+ V
Sbjct: 308 TKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVA----------- 356
Query: 187 VIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDASAQTTSHELT 246
A ++Q + IP +L + S P + +A + Q E+
Sbjct: 357 -------AMSLQS-HLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMV 408
Query: 247 ---IPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP-VEGSTDRQVTITGSAASISLAQY 302
IP +G IIG++G I ++ + + A IKIA P S R V ITG + AQ
Sbjct: 409 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQG 468
Query: 303 LINVRLSSE 311
I +L E
Sbjct: 469 RIYGKLKEE 477
Score = 70.5 bits (171), Expect = 2e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 468 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 522
Query: 133 VAGDMLPNSTERAI 146
V D P+ ++ I
Sbjct: 523 VPRDQTPDENDQVI 536
>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
sapiens]
Length = 572
Score = 77.4 bits (189), Expect = 2e-14
Identities = 86/359 (23%), Positives = 145/359 (40%), Gaps = 81/359 (22%)
Query: 23 KEVGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKA---FAMIID 77
K VG IIG+ GE + +++ ESG +I I+ PER L G +I +A I+D
Sbjct: 87 KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVD 146
Query: 78 K------LEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ- 130
+ DI S+ T +++PAS+ G +IG+GG IK+++E TG +
Sbjct: 147 RCRNGPGFHNDIDSNSTIQ----------EILIPASKVGLVIGRGGETIKQLQERTGVKM 196
Query: 131 VQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE---------------------- 168
V + LP ++ + I G + + + + ++ E
Sbjct: 197 VMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSI 256
Query: 169 --SPPK---------------------GVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQ 205
S P+ GV I ++P SP A + Q+A
Sbjct: 257 EVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHA--A 314
Query: 206 PDLTKLHQLAMQQSHF-------PMTHGNTGFSAGLDASAQTTSHELTIPNDLIGCIIGR 258
+++L A ++ F G +S G Q ++ T+P D G +IG+
Sbjct: 315 HIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITY--TVPADKCGLVIGK 372
Query: 259 QGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRLSSETGG 314
G I I Q SGA +++ ++D R+ TI G I +A+ LI+ ++ G
Sbjct: 373 GGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKVGGTNLG 431
Score = 70.9 bits (172), Expect = 1e-12
Identities = 58/182 (31%), Positives = 83/182 (45%), Gaps = 22/182 (12%)
Query: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKL--- 79
VG +IG+ GE +KK++ ++G RI +G PER + GP + A A II +L
Sbjct: 265 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHA-AHIISELILT 323
Query: 80 --EEDISSSMTN-----------STAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
E D + S A + VPA +CG +IGKGG IK I +
Sbjct: 324 AQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQ 383
Query: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSS 184
+GA V++ + PNS R TI G+PQ IE +Q+ + G + P S
Sbjct: 384 SGAHVELQRNPPPNSDPNLRRFTIRGVPQQ-IEVARQLIDEKVGGTNLGAPGAFGQSPFS 442
Query: 185 SP 186
P
Sbjct: 443 QP 444
Score = 47.4 bits (111), Expect = 2e-05
Identities = 23/63 (36%), Positives = 39/63 (61%)
Query: 242 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 301
+ E +P+ ++G IIGR G +I+ I+ SG +I+IA+ G +R +TG+ SI A+
Sbjct: 79 TEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAK 138
Query: 302 YLI 304
L+
Sbjct: 139 RLL 141
Score = 38.5 bits (88), Expect = 0.008
Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Query: 95 RPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQS 154
R +T VP G +IG+GG +I I+ +G ++Q+A + ER + G P+S
Sbjct: 75 RTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASES-SGIPERPCVLTGTPES 133
Query: 155 I 155
I
Sbjct: 134 I 134
>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
Length = 492
Score = 77.0 bits (188), Expect = 2e-14
Identities = 52/173 (30%), Positives = 91/173 (52%), Gaps = 21/173 (12%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 35 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
Query: 71 AFAMIIDKLEEDISSSMTNSTAAS--RPPVTL--------RLVVPASQCGSLIGKGGCKI 120
+ I +K+ E I +MT + +P T+ +L+VP S G +IGKGG +
Sbjct: 95 VHSFIAEKVRE-IPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATV 153
Query: 121 KEIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLESP 170
K + E +GA VQ++ P N ER +T++G P+ + + V I + E P
Sbjct: 154 KAVMEQSGAWVQLS--QKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDP 204
Score = 60.8 bits (146), Expect = 1e-09
Identities = 31/78 (39%), Positives = 53/78 (67%), Gaps = 3/78 (3%)
Query: 244 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 300
E+ +P +L+G I+G+ G + E ++++GA+I+I+ E G+ +R+VTITGS A+ A
Sbjct: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAA 469
Query: 301 QYLINVRLSSETGGMGSS 318
QYLI+ R++ E G S+
Sbjct: 470 QYLISQRVTYEQGVRASN 487
Score = 57.8 bits (138), Expect = 1e-08
Identities = 49/205 (23%), Positives = 89/205 (43%), Gaps = 51/205 (24%)
Query: 100 LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAG--DMLPNSTERAITIAGIPQSIIE 157
L++++P+ GS+IGKGG I ++++ TGA ++++ D P +TER + G +++
Sbjct: 35 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
Query: 158 CVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQ 217
I + E P A+ +P++ + Q
Sbjct: 95 VHSFIAEKVREIPQ------------------------------AMTKPEVVNILQ---- 120
Query: 218 QSHFPMTHGNTGFSAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIA 277
P T N D + Q +L +PN G IIG+ GA + + + SGA ++++
Sbjct: 121 ----PQTTMNP------DRAKQA---KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLS 167
Query: 278 NPVEGST--DRQVTITGSAASISLA 300
EG +R VT++G + A
Sbjct: 168 QKPEGINLQERVVTVSGEPEQVHKA 192
Score = 54.3 bits (129), Expect = 1e-07
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 17/118 (14%)
Query: 17 RLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKAF 72
+L++ G IIGK G +VK + E+SGA + +S+ N ER++T++G + KA
Sbjct: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
Query: 73 AMIIDKLEEDISSS-------------MTNSTAASRPPVTLRLVVPASQCGSLIGKGG 117
+ I+ K++ED SS + NS P + V+PA+ S G
Sbjct: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASG 251
Score = 47.8 bits (112), Expect = 1e-05
Identities = 23/63 (36%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Query: 92 AASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVA--GDMLPNSTERAITIA 149
AA + + VP + G+++GKGG + E +E TGA++Q++ G+ LP + R +TI
Sbjct: 401 AAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTIT 460
Query: 150 GIP 152
G P
Sbjct: 461 GSP 463
Score = 33.5 bits (75), Expect = 0.26
Identities = 18/64 (28%), Positives = 37/64 (57%), Gaps = 3/64 (4%)
Query: 244 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 300
++ IP+ G IIG+ G I ++++ +GA IK++ + G+T+R + G+A +++
Sbjct: 36 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAV 95
Query: 301 QYLI 304
I
Sbjct: 96 HSFI 99
Score = 29.6 bits (65), Expect = 3.7
Identities = 13/27 (48%), Positives = 22/27 (81%)
Query: 25 VGSIIGKKGESVKKMREESGARINISE 51
VG+I+GK G+++ + +E +GARI IS+
Sbjct: 418 VGAILGKGGKTLVEYQELTGARIQISK 444
>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
isoform b [Homo sapiens]
Length = 556
Score = 73.9 bits (180), Expect = 2e-13
Identities = 73/307 (23%), Positives = 134/307 (43%), Gaps = 49/307 (15%)
Query: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
Query: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
+A MI++ ++++ + + L+++ G LIGK G +K+I TG
Sbjct: 252 SEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETG 305
Query: 129 AQVQVAG--DMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSP 186
++ ++ D+ + ER IT+ G ++ +I + E+ +
Sbjct: 306 TKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDML----------- 354
Query: 187 VIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDASAQTTSHELT 246
T G ++ P HQ FP H + + L
Sbjct: 355 ------AVNTHSGYFSSLYPH----HQF----GPFPHHH----------SYPEQEIVNLF 390
Query: 247 IPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITGSAASISLAQYLI 304
IP +G IIG++GA I ++ + +GA IKIA P EG ++R V ITG + AQ I
Sbjct: 391 IPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGPPEAQFKAQGRI 449
Query: 305 NVRLSSE 311
+L E
Sbjct: 450 FGKLKEE 456
Score = 73.9 bits (180), Expect = 2e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 447 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 501
Query: 133 VAGDMLPNSTERAI 146
V D P+ E I
Sbjct: 502 VPRDQTPDENEEVI 515
>gi|17402900 far upstream element-binding protein [Homo sapiens]
Length = 644
Score = 73.2 bits (178), Expect = 3e-13
Identities = 54/183 (29%), Positives = 86/183 (46%), Gaps = 22/183 (12%)
Query: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
VG +IG+ GE +KK++ ++G RI +G PERI + GP + A +I D L
Sbjct: 287 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSV 346
Query: 83 ISSSMTNSTAASR------------PPVTLR---LVVPASQCGSLIGKGGCKIKEIREST 127
+ + R PP L+ +VP + G +IGKGG IK I + +
Sbjct: 347 QAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQS 406
Query: 128 GAQVQVAGDMLPNS--TERAITIAGIPQSIIECVKQICVVMLESP--PKGVTIPYRPKPS 183
GA++++ + PN+ + TI G PQ I+ +Q+ + P P G +P+ P
Sbjct: 407 GARIELQRNPPPNADPNMKLFTIRGTPQQ-IDYARQLIEEKIGGPVNPLGPPVPHGPHGV 465
Query: 184 SSP 186
P
Sbjct: 466 PGP 468
Score = 66.2 bits (160), Expect = 4e-11
Identities = 67/294 (22%), Positives = 121/294 (41%), Gaps = 60/294 (20%)
Query: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
VG IIG+ GE + ++++ESG +I I+ G PER L G ++ A ++D++ E
Sbjct: 112 VGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSA-KRLLDQIVEK 170
Query: 83 ISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNS- 141
+ +++PAS+ G +IGKGG IK+++E G ++ + D N+
Sbjct: 171 GRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTG 230
Query: 142 TERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQY 201
++ + I G P + + + + ++ + G ++ +Y
Sbjct: 231 ADKPLRITGDPYKVQQAKEMVLELIRDQ----------------------GGFREVRNEY 268
Query: 202 AIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDASAQTTSHELTIPNDLIGCIIGRQGA 261
G + G+D + IP +G +IGR G
Sbjct: 269 G-----------------------SRIGGNEGID---------VPIPRFAVGIVIGRNGE 296
Query: 262 KINEIRQMSGAQIKIANPVEGST-DRQVTITGSAASISLAQYLINVRLSSETGG 314
I +I+ +G +I+ P +G+T +R ITG A +I L S G
Sbjct: 297 MIKKIQNDAGVRIQF-KPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAG 349
Score = 54.7 bits (130), Expect = 1e-07
Identities = 68/308 (22%), Positives = 124/308 (40%), Gaps = 51/308 (16%)
Query: 18 LLMHGKEVGSIIGKKGESVKKMREESGAR-INISEG---NCPERIITLAGPTNAIFKAFA 73
+++ + G +IGK GE++K+++E +G + + I +G ++ + + G + +A
Sbjct: 190 IMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKE 249
Query: 74 MIIDKLEEDISSSMTNSTAASR--PPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQV 131
M+++ + + + SR + + +P G +IG+ G IK+I+ G ++
Sbjct: 250 MVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRI 309
Query: 132 QVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAG 191
Q D + ER I G P + +I +L S G P P P G
Sbjct: 310 QFKPDD-GTTPERIAQITG-PPDRCQHAAEIITDLLRSVQAG--NPGGPGP-------GG 358
Query: 192 GQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDASAQTTSHELTIPNDL 251
QG + + P +Q+ +F + G TG
Sbjct: 359 RGRGRGQGNWNMGPPG-------GLQEFNFIVPTGKTGL--------------------- 390
Query: 252 IGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRL 308
IIG+ G I I Q SGA+I++ + D + TI G+ I A+ LI ++
Sbjct: 391 ---IIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKI 447
Query: 309 SSETGGMG 316
+G
Sbjct: 448 GGPVNPLG 455
Score = 48.1 bits (113), Expect = 1e-05
Identities = 24/69 (34%), Positives = 41/69 (59%)
Query: 237 SAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAAS 296
S + E +P+ ++G IIGR G +I+ I+Q SG +I+IA G +R +TG+ S
Sbjct: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPES 156
Query: 297 ISLAQYLIN 305
+ A+ L++
Sbjct: 157 VQSAKRLLD 165
>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
[Homo sapiens]
Length = 579
Score = 72.8 bits (177), Expect = 4e-13
Identities = 80/318 (25%), Positives = 148/318 (46%), Gaps = 56/318 (17%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAGP--TNA 67
L +RLL+ + VG+IIGK+G +++ + +++ ++I++ + G + I L+ P T+A
Sbjct: 196 LPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSA 255
Query: 68 IFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIREST 127
K+ I+ K +DI + + L+++ + G LIGK G +K+I + T
Sbjct: 256 ACKSILEIMHKEAQDIKFT---------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDT 306
Query: 128 GAQVQVA--GDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSS 185
++ ++ ++ + ER IT+ G ++ + ++I + ES +
Sbjct: 307 DTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRES-------------YEN 353
Query: 186 PVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDAS-------- 237
+ QA+ I G L+ L + FP T G ++G ++
Sbjct: 354 DIASMNLQAHLIPG---------LNLNALGL----FPPTSGMPPPTSGPPSAMTPPYPQF 400
Query: 238 --AQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEG--STDRQVTITGS 293
++T + L IP +G IIG+QG I ++ + +GA IKIA P E + R V ITG
Sbjct: 401 EQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIA-PAEAPDAKVRMVIITGP 459
Query: 294 AASISLAQYLINVRLSSE 311
+ AQ I ++ E
Sbjct: 460 PEAQFKAQGRIYGKIKEE 477
Score = 70.5 bits (171), Expect = 2e-12
Identities = 41/137 (29%), Positives = 71/137 (51%), Gaps = 8/137 (5%)
Query: 13 TLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIF 69
T T+ L + VG+IIGK+G+ +K++ +GA I I+ P+ R++ + GP A F
Sbjct: 405 TETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQF 464
Query: 70 KAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGA 129
KA I K++E+ S + + VP+ G +IGKGG + E++ + A
Sbjct: 465 KAQGRIYGKIKEENFVSPKEEV-----KLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSA 519
Query: 130 QVQVAGDMLPNSTERAI 146
+V V D P+ ++ +
Sbjct: 520 EVVVPRDQTPDENDQVV 536
Score = 30.4 bits (67), Expect = 2.2
Identities = 16/59 (27%), Positives = 31/59 (52%), Gaps = 2/59 (3%)
Query: 245 LTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVT--ITGSAASISLAQ 301
+ +P+ G +IG+ G +NE++ +S A++ + + QV ITG + +AQ
Sbjct: 492 IRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQ 550
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 72.8 bits (177), Expect = 4e-13
Identities = 80/341 (23%), Positives = 141/341 (41%), Gaps = 58/341 (17%)
Query: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
VG IIG+ GE + K++++SG ++ IS G PER ++L G ++ KA M+ D +
Sbjct: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215
Query: 83 ISS---SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139
++ + +++PA + G +IGKGG IK+++E G ++ + D
Sbjct: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275
Query: 140 N-STERAITIAGIPQSIIECVKQICVVMLESPP--------------KGVTIPYRPKPSS 184
N + ++ + I G P + + + + ++ E G+ +P P+ S
Sbjct: 276 NTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-PRHSV 334
Query: 185 SPVIFAGGQAY-TIQGQYAI----PQPDLTKLHQLA---------------------MQQ 218
VI G+ IQ + Q D T ++A +
Sbjct: 335 GVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR 394
Query: 219 SHFPMTHGNTGFSAGLDASAQTTSH------ELT--IPNDLIGCIIGRQGAKINEIRQMS 270
S P G G G + + E+T IP G +IGR G + I Q +
Sbjct: 395 SGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQT 454
Query: 271 GAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRL 308
GA ++I+ + + D + I GS I A+ LI ++
Sbjct: 455 GAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495
Score = 69.7 bits (169), Expect = 3e-12
Identities = 53/190 (27%), Positives = 82/190 (43%), Gaps = 33/190 (17%)
Query: 25 VGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
VG +IG+ GE +KK++ ++G RI + G PE+I + GP + A +I D L+
Sbjct: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393
Query: 83 ISSSMTNSTAASRPPV----------------TLRLVVPASQCGSLIGKGGCKIKEIRES 126
S PP + +P +CG +IG+GG +K I +
Sbjct: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453
Query: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLESP------------PK 172
TGA V+++ + PN + I G PQ I+ KQ+ +E P P
Sbjct: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQ-IDHAKQLIEEKIEGPLCPVGPGPGGPGPA 512
Query: 173 GVTIPYRPKP 182
G P+ P P
Sbjct: 513 GPMGPFNPGP 522
Score = 53.1 bits (126), Expect = 3e-07
Identities = 25/73 (34%), Positives = 47/73 (64%)
Query: 242 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 301
+ E +P+ ++G IIGR G +IN+I+Q SG +++I+ G +R V++TG+ S+ A+
Sbjct: 146 TEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAK 205
Query: 302 YLINVRLSSETGG 314
+++ +S GG
Sbjct: 206 MMLDDIVSRGRGG 218
Score = 43.1 bits (100), Expect = 3e-04
Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 5/77 (6%)
Query: 81 EDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138
+ ISS + R +T VP G +IG+GG +I +I++ +G +VQ++ D L
Sbjct: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187
Query: 139 PNSTERAITIAGIPQSI 155
P ER++++ G P+S+
Sbjct: 188 P---ERSVSLTGAPESV 201
>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
isoform 2 [Homo sapiens]
Length = 438
Score = 70.5 bits (171), Expect = 2e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 329 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 383
Query: 133 VAGDMLPNSTERAI 146
V D P+ ++ I
Sbjct: 384 VPRDQTPDENDQVI 397
Score = 58.2 bits (139), Expect = 1e-08
Identities = 44/184 (23%), Positives = 80/184 (43%), Gaps = 45/184 (24%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
+++L H VG +IGK+G ++KK+ +++ +I IS PER IT+ G +
Sbjct: 140 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 199
Query: 71 AFAMIIDKLEEDISSSM----------------------TNSTAASRPPVT--------- 99
A I+ K+ E + + +S+A PP +
Sbjct: 200 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 259
Query: 100 ---------LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
+++ +PA G++IGK G IK++ A +++A P+S R + I G
Sbjct: 260 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 319
Query: 151 IPQS 154
P++
Sbjct: 320 PPEA 323
Score = 54.7 bits (130), Expect = 1e-07
Identities = 57/247 (23%), Positives = 105/247 (42%), Gaps = 31/247 (12%)
Query: 77 DKLEEDISSSMTNSTAASRPP------VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ 130
+++ + +++ N T ++R V L+++ + G LIGK G +K++ + T +
Sbjct: 111 EQVNTESETAVVNVTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETK 170
Query: 131 VQVAG--DMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVI 188
+ ++ D+ + ER IT+ G ++ ++I + E+ V
Sbjct: 171 ITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVA------------- 217
Query: 189 FAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDASAQTTSHELT-- 246
A ++Q + IP +L + S P + +A + Q E+
Sbjct: 218 -----AMSLQS-HLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQV 271
Query: 247 -IPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP-VEGSTDRQVTITGSAASISLAQYLI 304
IP +G IIG++G I ++ + + A IKIA P S R V ITG + AQ I
Sbjct: 272 FIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRI 331
Query: 305 NVRLSSE 311
+L E
Sbjct: 332 YGKLKEE 338
>gi|122937472 bicaudal C homolog 1 [Homo sapiens]
Length = 974
Score = 64.3 bits (155), Expect = 1e-10
Identities = 80/294 (27%), Positives = 126/294 (42%), Gaps = 33/294 (11%)
Query: 30 GKKGESV-KKMREESGARI------NISEGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
G+ GE +K+ EE+ +I I + + I ++G + +A MI+ L+
Sbjct: 70 GRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLD-- 127
Query: 83 ISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNST 142
T ++R VTL++ V ++ +IGKGG IK++ E TG + N
Sbjct: 128 --------TKSNR--VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQA 177
Query: 143 ERA--ITIAGIPQSIIECVKQI-----CVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAY 195
E++ ++IAG P + +I V+M E P G+ P P P+S P I Q Y
Sbjct: 178 EKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPV-PDPNS-PSIQHISQTY 235
Query: 196 TIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFS----AGLDASAQTTSHELTIPNDL 251
I + + Q++ T AG ASA S +L I
Sbjct: 236 NISVSFKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQH 295
Query: 252 IGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLA-QYLI 304
++GR G+ I I Q +GAQI +P V + G+ S+ LA QYL+
Sbjct: 296 HLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLM 349
Score = 32.0 bits (71), Expect = 0.75
Identities = 13/40 (32%), Positives = 25/40 (62%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN 53
+T+++ + E +IGK G ++KK+ EE+G I+ + N
Sbjct: 133 VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSN 172
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 55.1 bits (131), Expect = 8e-08
Identities = 35/119 (29%), Positives = 70/119 (58%), Gaps = 14/119 (11%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI-SEGNCPERIITLAGPTNAIFKAF 72
+ I + + + V IIG++G ++K++R+++GARI++ +E ER++ ++G F
Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISG--------F 104
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQV 131
+ + K + I +T +T PV+ +L VP G +IG+GG I+ I +++GA++
Sbjct: 105 PVQVCKAKAAIHQILTENT-----PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKI 158
Score = 42.7 bits (99), Expect = 4e-04
Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 3/103 (2%)
Query: 91 TAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
T + + + VP +IG+ G IK++R+ TGA++ V D ER + I+G
Sbjct: 46 TFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--DTEDVGDERVLLISG 103
Query: 151 IPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQ 193
P + + I ++ E+ P + P+ S +I GG+
Sbjct: 104 FPVQVCKAKAAIHQILTENTPVSEQLSV-PQRSVGRIIGRGGE 145
Score = 41.6 bits (96), Expect = 0.001
Identities = 24/72 (33%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Query: 242 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITGSAASISL 299
S +L++P +G IIGR G I I + SGA+I EG+ R + I+G+ ++
Sbjct: 126 SEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAA 185
Query: 300 AQYLINVRLSSE 311
A++LI ++S +
Sbjct: 186 AKHLILEKVSED 197
Score = 40.8 bits (94), Expect = 0.002
Identities = 22/69 (31%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Query: 244 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 303
E+ +P + + IIGRQGA I ++R+ +GA+I + G +R + I+G + A+
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD-ERVLLISGFPVQVCKAKAA 114
Query: 304 INVRLSSET 312
I+ L+ T
Sbjct: 115 IHQILTENT 123
Score = 39.3 bits (90), Expect = 0.005
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 4/76 (5%)
Query: 11 NVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGN-CPERIITLAGPTN 66
N ++ +L + + VG IIG+ GE+++ + + SGA+I SEG R+I ++G
Sbjct: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181
Query: 67 AIFKAFAMIIDKLEED 82
+ A +I++K+ ED
Sbjct: 182 EVAAAKHLILEKVSED 197
>gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 55.1 bits (131), Expect = 8e-08
Identities = 35/119 (29%), Positives = 70/119 (58%), Gaps = 14/119 (11%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI-SEGNCPERIITLAGPTNAIFKAF 72
+ I + + + V IIG++G ++K++R+++GARI++ +E ER++ ++G F
Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISG--------F 104
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQV 131
+ + K + I +T +T PV+ +L VP G +IG+GG I+ I +++GA++
Sbjct: 105 PVQVCKAKAAIHQILTENT-----PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKI 158
Score = 42.7 bits (99), Expect = 4e-04
Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 3/103 (2%)
Query: 91 TAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
T + + + VP +IG+ G IK++R+ TGA++ V D ER + I+G
Sbjct: 46 TFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--DTEDVGDERVLLISG 103
Query: 151 IPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQ 193
P + + I ++ E+ P + P+ S +I GG+
Sbjct: 104 FPVQVCKAKAAIHQILTENTPVSEQLSV-PQRSVGRIIGRGGE 145
Score = 41.6 bits (96), Expect = 0.001
Identities = 24/72 (33%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Query: 242 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITGSAASISL 299
S +L++P +G IIGR G I I + SGA+I EG+ R + I+G+ ++
Sbjct: 126 SEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAA 185
Query: 300 AQYLINVRLSSE 311
A++LI ++S +
Sbjct: 186 AKHLILEKVSED 197
Score = 40.8 bits (94), Expect = 0.002
Identities = 22/69 (31%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Query: 244 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 303
E+ +P + + IIGRQGA I ++R+ +GA+I + G +R + I+G + A+
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD-ERVLLISGFPVQVCKAKAA 114
Query: 304 INVRLSSET 312
I+ L+ T
Sbjct: 115 IHQILTENT 123
Score = 39.3 bits (90), Expect = 0.005
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 4/76 (5%)
Query: 11 NVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGN-CPERIITLAGPTN 66
N ++ +L + + VG IIG+ GE+++ + + SGA+I SEG R+I ++G
Sbjct: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181
Query: 67 AIFKAFAMIIDKLEED 82
+ A +I++K+ ED
Sbjct: 182 EVAAAKHLILEKVSED 197
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,013,077
Number of Sequences: 37866
Number of extensions: 542089
Number of successful extensions: 1346
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 959
Number of HSP's gapped (non-prelim): 244
length of query: 318
length of database: 18,247,518
effective HSP length: 102
effective length of query: 216
effective length of database: 14,385,186
effective search space: 3107200176
effective search space used: 3107200176
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.