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Search of human proteins with 190014607
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|190014607 netrin G2 [Homo sapiens]
(530 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|190014607 netrin G2 [Homo sapiens] 1156 0.0
gi|164414431 netrin G1 isoform 1 [Homo sapiens] 691 0.0
gi|164414437 netrin G1 isoform 2 [Homo sapiens] 444 e-124
gi|54312078 netrin G1 isoform 3 [Homo sapiens] 440 e-123
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 209 7e-54
gi|148613884 netrin 1 [Homo sapiens] 204 1e-52
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 197 3e-50
gi|5453810 netrin 3 [Homo sapiens] 194 1e-49
gi|21264602 laminin alpha 5 [Homo sapiens] 189 5e-48
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 169 8e-42
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 169 8e-42
gi|143770880 laminin, beta 4 [Homo sapiens] 167 2e-41
gi|93204871 netrin 4 [Homo sapiens] 162 7e-40
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 158 1e-38
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 152 1e-36
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 152 1e-36
gi|189083719 laminin, beta 3 precursor [Homo sapiens] 152 1e-36
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 147 3e-35
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 142 6e-34
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 134 2e-31
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 134 2e-31
gi|219842266 usherin isoform B [Homo sapiens] 126 4e-29
gi|219842259 usherin isoform A [Homo sapiens] 126 4e-29
gi|24308065 netrin 5 [Homo sapiens] 115 1e-25
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 97 3e-20
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 97 3e-20
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 96 1e-19
gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 75 1e-13
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 75 2e-13
gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] 75 2e-13
>gi|190014607 netrin G2 [Homo sapiens]
Length = 530
Score = 1156 bits (2991), Expect = 0.0
Identities = 530/530 (100%), Positives = 530/530 (100%)
Query: 1 MLHLLALFLHCLPLASGDYDICKSWVTTDEGPTWEFYACQPKVMRLKDYVKVKVEPSGIT 60
MLHLLALFLHCLPLASGDYDICKSWVTTDEGPTWEFYACQPKVMRLKDYVKVKVEPSGIT
Sbjct: 1 MLHLLALFLHCLPLASGDYDICKSWVTTDEGPTWEFYACQPKVMRLKDYVKVKVEPSGIT 60
Query: 61 CGDPPERFCSHENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLE 120
CGDPPERFCSHENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLE
Sbjct: 61 CGDPPERFCSHENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLE 120
Query: 121 ANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSAR 180
ANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSAR
Sbjct: 121 ANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSAR 180
Query: 181 RARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESA 240
RARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESA
Sbjct: 181 RARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESA 240
Query: 241 KGLKEFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSMRE 300
KGLKEFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSMRE
Sbjct: 241 KGLKEFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSMRE 300
Query: 301 GSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSN 360
GSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSN
Sbjct: 301 GSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSN 360
Query: 361 RCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDR 420
RCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDR
Sbjct: 361 RCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDR 420
Query: 421 CNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRG 480
CNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRG
Sbjct: 421 CNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRG 480
Query: 481 YTGVRCEQPRCDPADDDGGLDCDRAPGAAPRPATLLGCLLLLGLAARLGR 530
YTGVRCEQPRCDPADDDGGLDCDRAPGAAPRPATLLGCLLLLGLAARLGR
Sbjct: 481 YTGVRCEQPRCDPADDDGGLDCDRAPGAAPRPATLLGCLLLLGLAARLGR 530
>gi|164414431 netrin G1 isoform 1 [Homo sapiens]
Length = 539
Score = 691 bits (1782), Expect = 0.0
Identities = 311/519 (59%), Positives = 384/519 (73%), Gaps = 8/519 (1%)
Query: 13 PLASGDYDICKSWVTTDEGPTWEFYACQPKVMRLKDYVKVKVEPSGITCGDPPERFCSHE 72
PL G YD+CK+ + T+EG W++ ACQP+ + Y+KVK++P ITCGDPPE FC+
Sbjct: 24 PLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPETFCAMG 83
Query: 73 NPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVE 132
NPY+C+NECDAS P+LAHPP LMFD E +T+WQS TW YP PL+ NITLSW+KT+E
Sbjct: 84 NPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIE 143
Query: 133 LTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSARRARDMSSSSAHR 192
LTD++V+TFE GRP M+LEKSLD GRTWQPYQ+YA DC++AF M + +D+S +
Sbjct: 144 LTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLE 203
Query: 193 VLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDL 252
++CTEEYS + K + FE++DRFA FAGP LRNM +LY +L++ K L++FFT+TDL
Sbjct: 204 IICTEEYST-GYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDL 262
Query: 253 RMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSMREGSLQCECEHNTT 312
R+RLLRPA+G +V +L +YFYAIS+I+V GRCKCNLHA +C L CECEHNTT
Sbjct: 263 RIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTT 322
Query: 313 GPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC-ATAGSFGNCECYGHSNRCSYIDFLNVV 371
GPDCGKCKKN++ R W GSYLP+P G+ N C + S GNCEC+GHSNRCSYID LN V
Sbjct: 323 GPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTV 382
Query: 372 TCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECRE 431
CVSCKHNTRGQHC+ CRLGY+RN SA+LDDENVCIEC CN +GS+HDRCN +GFCEC+
Sbjct: 383 ICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKT 442
Query: 432 GAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRC 491
G GPKCD+CLP + W GC PNVCD++ L CQNGGTC N RC CP YTG+ CE+ RC
Sbjct: 443 GTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRC 502
Query: 492 DPADDDGGLDCDRAPGAAPR--PATLLGCLLLLGLAARL 528
+ A G D GA P PA LL LLG A+ L
Sbjct: 503 EEA---GSCGSDSGQGAPPHGSPALLL-LTTLLGTASPL 537
>gi|164414437 netrin G1 isoform 2 [Homo sapiens]
Length = 480
Score = 444 bits (1141), Expect = e-124
Identities = 215/439 (48%), Positives = 284/439 (64%), Gaps = 19/439 (4%)
Query: 13 PLASGDYDICKSWVTTDEGPTWEFYACQPKVMRLKDYVKVKVEPSGITCGDPPERFCSHE 72
PL G YD+CK+ + T+EG W++ ACQP+ + Y+KVK++P ITCGDPPE FC+
Sbjct: 24 PLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPETFCAMG 83
Query: 73 NPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVE 132
NPY+C+NECDAS P+LAHPP LMFD E +T+WQS TW YP PL+ NITLSW+KT+E
Sbjct: 84 NPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIE 143
Query: 133 LTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSARRARDMSSSSAHR 192
LTD++V+TFE GRP M+LEKSLD GRTWQPYQ+YA DC++AF M + +D+S +
Sbjct: 144 LTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLE 203
Query: 193 VLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDL 252
++CTEEYS + K + FE++DRFA FAGP LRNM +LY +L++ K L++FFT+TDL
Sbjct: 204 IICTEEYST-GYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDL 262
Query: 253 RMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSMREGSLQCECEHNTT 312
R+RLLRPA+G +V +L +YFYAIS+I+V GRCKCNLHA +C L CECEHNTT
Sbjct: 263 RIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTT 322
Query: 313 GPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC-ATAGSFGNCECY------------GHS 359
GPDCGKCKKN++ R W GSYLP+P G+ N C + S GN + +
Sbjct: 323 GPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNPPKFNRIWPNISSLEVSNP 382
Query: 360 NRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHD 419
+ + L+ V+ V ++ R C + L G+ NV C G + +
Sbjct: 383 KQVAPKLALSTVSSVQVANHKRANVCDNELLHCQNGGTCH---NNVRCLCPAAYTGILCE 439
Query: 420 --RCNETGFCECREGAAGP 436
RC E G C G P
Sbjct: 440 KLRCEEAGSCGSDSGQGAP 458
Score = 78.6 bits (192), Expect = 1e-14
Identities = 66/192 (34%), Positives = 87/192 (45%), Gaps = 22/192 (11%)
Query: 351 GNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGY----YRNGS---AELDDE 403
G C+C H+ C Y + + +TC C+HNT G C C+ Y + GS
Sbjct: 295 GRCKCNLHATVCVYDN--SKLTC-ECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTA 351
Query: 404 NVCIECNCNQIGSV--HDRC--NETGFCECREGAAGPKCD-DCLPTHYWRQGCYPNVCDD 458
N CI + + IG+ +R N + PK + + NVCD+
Sbjct: 352 NTCIP-SISSIGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSVQVANHKRANVCDN 410
Query: 459 DQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDPADDDGGLDCDRAPGAAPR--PATLL 516
+ L CQNGGTC N RC CP YTG+ CE+ RC+ A G D GA P PA LL
Sbjct: 411 ELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEA---GSCGSDSGQGAPPHGSPALLL 467
Query: 517 GCLLLLGLAARL 528
LLG A+ L
Sbjct: 468 -LTTLLGTASPL 478
Score = 31.6 bits (70), Expect = 1.9
Identities = 17/56 (30%), Positives = 20/56 (35%), Gaps = 3/56 (5%)
Query: 400 LDDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHY---WRQGCY 452
+ D V C CN +V N CEC GP C C + W G Y
Sbjct: 288 ISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSY 343
>gi|54312078 netrin G1 isoform 3 [Homo sapiens]
Length = 438
Score = 440 bits (1132), Expect = e-123
Identities = 198/351 (56%), Positives = 255/351 (72%), Gaps = 2/351 (0%)
Query: 13 PLASGDYDICKSWVTTDEGPTWEFYACQPKVMRLKDYVKVKVEPSGITCGDPPERFCSHE 72
PL G YD+CK+ + T+EG W++ ACQP+ + Y+KVK++P ITCGDPPE FC+
Sbjct: 24 PLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPETFCAMG 83
Query: 73 NPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVE 132
NPY+C+NECDAS P+LAHPP LMFD E +T+WQS TW YP PL+ NITLSW+KT+E
Sbjct: 84 NPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIE 143
Query: 133 LTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSARRARDMSSSSAHR 192
LTD++V+TFE GRP M+LEKSLD GRTWQPYQ+YA DC++AF M + +D+S +
Sbjct: 144 LTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLE 203
Query: 193 VLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDL 252
++CTEEYS + K + FE++DRFA FAGP LRNM +LY +L++ K L++FFT+TDL
Sbjct: 204 IICTEEYST-GYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDL 262
Query: 253 RMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSMREGSLQCECEHNTT 312
R+RLLRPA+G +V +L +YFYAIS+I+V GRCKCNLHA +C L CECEHNTT
Sbjct: 263 RIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTT 322
Query: 313 GPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC-ATAGSFGNCECYGHSNRC 362
GPDCGKCKKN++ R W GSYLP+P G+ N C + S G C C
Sbjct: 323 GPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCDNELLHC 373
Score = 85.5 bits (210), Expect = 1e-16
Identities = 56/153 (36%), Positives = 65/153 (42%), Gaps = 28/153 (18%)
Query: 400 LDDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHY---WRQGCY---- 452
+ D V C CN +V N CEC GP C C + W G Y
Sbjct: 288 ISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIP 347
Query: 453 ---------------PNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDPADDD 497
NVCD++ L CQNGGTC N RC CP YTG+ CE+ RC+ A
Sbjct: 348 KGTANTCIPSISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEA--- 404
Query: 498 GGLDCDRAPGAAPR--PATLLGCLLLLGLAARL 528
G D GA P PA LL LLG A+ L
Sbjct: 405 GSCGSDSGQGAPPHGSPALLL-LTTLLGTASPL 436
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 209 bits (531), Expect = 7e-54
Identities = 151/482 (31%), Positives = 207/482 (42%), Gaps = 59/482 (12%)
Query: 28 TDEGPTWEFYACQPKVMRLKDYVKVKVEPSGITCGDPPERFCSHENPYLCSNEC---DAS 84
TDEG + C P+ + V V TCG PPE +C + C DA
Sbjct: 41 TDEGGRPQ--RCMPEFVNAAFNVTVVATN---TCGTPPEEYCVQTGVTGVTKSCHLCDAG 95
Query: 85 NPDLAHPPRLMFDKEEEGLATYWQSITWS---RYPSPLEANITLSWNKTVELTDDVVMTF 141
P L H + D + T+WQS T +YPS + N+TL K ++T V + F
Sbjct: 96 QPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPSSI--NLTLHLGKAFDITY-VRLKF 152
Query: 142 EYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSARRARDMSSSSAHRVLCTEEYSR 201
RP + K W PYQ+Y+ C + A R + + LCT+E+S
Sbjct: 153 HTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYS-KANRGFIRTGGDEQQALCTDEFSD 211
Query: 202 WAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMRLLRPAL 261
+V F + P N DN + L+E+ T TD+R+ L R
Sbjct: 212 -ISPLTGGNVAFSTLE-----GRPSAYNFDN-------SPVLQEWVTATDIRVTLNRLNT 258
Query: 262 GGTYVQREN--LYKYFYAISNIEVIGRCKCNLHANLCSMRE-GSLQCECEHNTTGPDCGK 318
G V + L Y+YAIS+ V GRCKCN HA+ C E L C C+HNT G DC K
Sbjct: 259 FGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEK 318
Query: 319 CKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVT-----C 373
C F R WR + +A C+C G S C + L T C
Sbjct: 319 CLPFFNDRPWRRAT-----------AESASECLPCDCNGRSQECYFDPELYRSTGHGGHC 367
Query: 374 VSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECREGA 433
+C+ NT G HC+ CR ++R G+ E C C+C+ +GS+ +C+ G C C+ G
Sbjct: 368 TNCQDNTDGAHCERCRENFFRLGNNE-----ACSSCHCSPVGSLSTQCDSYGRCSCKPGV 422
Query: 434 AGPKCDDCLPTHY--WRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRC 491
G KCD C P + GC P CD + + ++ RC C G CE RC
Sbjct: 423 MGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDECN---IETGRCVCKDNVEGFNCE--RC 477
Query: 492 DP 493
P
Sbjct: 478 KP 479
Score = 84.7 bits (208), Expect = 2e-16
Identities = 61/209 (29%), Positives = 85/209 (40%), Gaps = 29/209 (13%)
Query: 286 RCKCNLHANL---CSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPN 342
+C N+ N C+ G +C +NT G C +CK F P P
Sbjct: 829 QCSDNIDPNAVGNCNRLTGEC-LKCIYNTAGFYCDRCKDGFF-----GNPLAPNPADKCK 882
Query: 343 ACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDD 402
AC NC YG + S + V C + GQ C C G+Y L
Sbjct: 883 AC-------NCNLYGTMKQQSSCN--PVTGQCECLPHVTGQDCGACDPGFYN-----LQS 928
Query: 403 ENVCIECNCNQIGSVHDRCN-ETGFCECREGAAGPKCDDCLPTHYW--RQGCYPNVCDDD 459
C C+C+ +GS + +C+ TG CEC+ G G C+ C H+ +GC P C +
Sbjct: 929 GQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPE 988
Query: 460 QLLCQNGGTCLQNQRCACPRGYTGVRCEQ 488
L C + RC C G+ G RC+Q
Sbjct: 989 GSLSLQ---CKDDGRCECREGFVGNRCDQ 1014
Score = 82.4 bits (202), Expect = 9e-16
Identities = 71/268 (26%), Positives = 91/268 (33%), Gaps = 84/268 (31%)
Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346
C CN H+ C G C C NT GP C KC + +G A T
Sbjct: 724 CACNGHSETCDPETGV--CNCRDNTAGPHCEKCSDGY--------------YGDSTA-GT 766
Query: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYY-----RNGSAEL- 400
+ C C G S+ C+ + V C +C T G+ C+ C GY+ RNG L
Sbjct: 767 SSDCQPCPCPGGSS-CAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLC 825
Query: 401 --------------------------------------------------DDENVCIECN 410
+ + C CN
Sbjct: 826 RLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACN 885
Query: 411 CNQIGSVHDR--CNE-TGFCECREGAAGPKCDDCLPTHY---WRQGCYPNVCDDDQLLCQ 464
CN G++ + CN TG CEC G C C P Y QGC CD L
Sbjct: 886 CNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGC--ERCDCHALGST 943
Query: 465 NGGTCLQNQRCACPRGYTGVRCEQPRCD 492
NG ++ +C C G TG CE RC+
Sbjct: 944 NGQCDIRTGQCECQPGITGQHCE--RCE 969
Score = 79.0 bits (193), Expect = 1e-14
Identities = 49/173 (28%), Positives = 72/173 (41%), Gaps = 36/173 (20%)
Query: 287 CKCNLHANL-----CSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSP 341
C CNL+ + C+ G QCEC + TG DCG C F S
Sbjct: 884 CNCNLYGTMKQQSSCNPVTG--QCECLPHVTGQDCGACDPGFYNLQ------------SG 929
Query: 342 NACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELD 401
C C+C+ + D + C C+ GQHC+ C + ++ G
Sbjct: 930 QGCE------RCDCHALGSTNGQCD-IRTGQC-ECQPGITGQHCERCEVNHFGFGPEG-- 979
Query: 402 DENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQ---GC 451
C C+C+ GS+ +C + G CECREG G +CD C +++ + GC
Sbjct: 980 ----CKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGC 1028
Score = 61.2 bits (147), Expect = 2e-09
Identities = 39/123 (31%), Positives = 49/123 (39%), Gaps = 10/123 (8%)
Query: 371 VTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECR 430
V +C GQ C+ C GY R + L + C+ C CN D ETG C CR
Sbjct: 687 VESCTCPVGYGGQFCEMCLSGYRRE-TPNLGPYSPCVLCACNGHSETCDP--ETGVCNCR 743
Query: 431 EGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCA------CPRGYTGV 484
+ AGP C+ C Y+ D C G +C + CP G TG
Sbjct: 744 DNTAGPHCEKC-SDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGK 802
Query: 485 RCE 487
RCE
Sbjct: 803 RCE 805
Score = 54.7 bits (130), Expect = 2e-07
Identities = 38/139 (27%), Positives = 50/139 (35%), Gaps = 23/139 (16%)
Query: 305 CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSY 364
C C G C C +R + G Y P C C C GHS C
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSP--------CVL------CACNGHSETCDP 735
Query: 365 IDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC--NQIGSVHDRCN 422
C +C+ NT G HC+ C GYY + +A + C C C +V +
Sbjct: 736 ----ETGVC-NCRDNTAGPHCEKCSDGYYGDSTAGTSSD--CQPCPCPGGSSCAVVPKTK 788
Query: 423 ETGFCECREGAAGPKCDDC 441
E C G G +C+ C
Sbjct: 789 EVVCTNCPTGTTGKRCELC 807
>gi|148613884 netrin 1 [Homo sapiens]
Length = 604
Score = 204 bits (520), Expect = 1e-52
Identities = 125/398 (31%), Positives = 190/398 (47%), Gaps = 45/398 (11%)
Query: 60 TCGDPPERFC----SHENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRY 115
TCG PP R+C E + C+AS+P AHPP + D T WQS + ++
Sbjct: 69 TCGRPPARYCVVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQF 128
Query: 116 PSPLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAF 175
P +TLS K E+T V + F RP M + KS+D GRTW P+QFY+ C + +
Sbjct: 129 PH--NVTLTLSLGKKFEVTY-VSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMY 185
Query: 176 GMSARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYT 235
R ++ + +CT+ ++ + F D P + DN
Sbjct: 186 NRPHRAP--ITKQNEQEAVCTDSHTDMRPLSGGL-IAFSTLD-----GRPSAHDFDN--- 234
Query: 236 RLESAKGLKEFFTLTDLRMRLLRPALGGTYVQRENLY---KYFYAISNIEVIGRCKCNLH 292
+ L+++ T TD+R+ R G + ++ YFYA+S+++V GRCKCN H
Sbjct: 235 ----SPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGH 290
Query: 293 ANLCSM-REGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFG 351
A C R+ SL C+C HNT GP+C +CK R W+ + N C
Sbjct: 291 AARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAR-----EANECVA----- 340
Query: 352 NCECYGHSNRCSYIDFLNVVT-------CVSCKHNTRGQHCQHCRLGYYRNGSAELDDEN 404
C C H+ RC + L ++ C++C+HNT G+HC +C+ GYYR+ +
Sbjct: 341 -CNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRK 399
Query: 405 VCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDC 441
C C+C+ +G+ CN+ TG C C++G G C+ C
Sbjct: 400 ACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRC 437
Score = 63.2 bits (152), Expect = 6e-10
Identities = 45/156 (28%), Positives = 64/156 (41%), Gaps = 20/156 (12%)
Query: 351 GNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNG--SAELDDENVCIE 408
G C+C GH+ RC D + + C C+HNT G C C+ +Y A + N C+
Sbjct: 283 GRCKCNGHAARCVR-DRDDSLVC-DCRHNTAGPECDRCKPFHYDRPWQRATAREANECVA 340
Query: 409 CNCN----------QIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQG---CYPNV 455
CNCN ++ + R + CR AG C C +Y G +
Sbjct: 341 CNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKA 400
Query: 456 CD--DDQLLCQNGGTCLQNQ-RCACPRGYTGVRCEQ 488
C D + G TC Q +C C G TG+ C +
Sbjct: 401 CKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNR 436
Score = 30.4 bits (67), Expect = 4.2
Identities = 17/67 (25%), Positives = 27/67 (40%), Gaps = 8/67 (11%)
Query: 287 CK-CNLH-----ANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGS 340
CK C+ H C+ G QC C+ TG C +C K ++ + +P
Sbjct: 401 CKACDCHPVGAAGKTCNQTTG--QCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAP 458
Query: 341 PNACATA 347
P A++
Sbjct: 459 PTTAASS 465
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 197 bits (500), Expect = 3e-50
Identities = 142/452 (31%), Positives = 199/452 (44%), Gaps = 58/452 (12%)
Query: 60 TCGDPPERFCSHENPYLCS---NECDASNPDLAHPPRLMFDKEEEGLATYWQSITWS--- 113
TCG PPE FC H CDA++P H + D + +T+WQS + +
Sbjct: 53 TCGSPPEDFCPHVGAAGAGAHCQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGV 112
Query: 114 RYPSPLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCME 173
+YP+ + NITL K E+T V + F RP + K W+PYQFY+ C +
Sbjct: 113 QYPTSV--NITLRLGKAYEITY-VRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQK 169
Query: 174 AFGMSARRARDMSSSSAHRV-LCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDN 232
+G + + RV CT E+S +V F L +
Sbjct: 170 TYGRP--EGQYLRPGEDERVAFCTSEFSD-ISPLSGGNVAFST-----------LEGRPS 215
Query: 233 LYTRLESAKGLKEFFTLTDLRMRLLRPALGGTYVQREN--LYKYFYAISNIEVIGRCKCN 290
Y E + GL+E+ T T+L + L R G + ++ L Y+YA+S+ V GRCKCN
Sbjct: 216 AYN-FEESPGLQEWVTSTELLISLDRLNTFGDDIFKDPKVLQSYYYAVSDFSVGGRCKCN 274
Query: 291 LHANLCSMR-EGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGS 349
HA+ C G L C C+HNTTG DC +C F+ R W G+ P
Sbjct: 275 GHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLP-------- 326
Query: 350 FGNCECYGHSNRCSYIDFLNVVT-----CVSCKHNTRGQHCQHCRLGYYRNGSAELDDEN 404
C C G S C++ L T C C+ +T G HC+ C+ +Y D
Sbjct: 327 ---CNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYH-----WDPRM 378
Query: 405 VCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHY--WRQGCYPNVCDDDQLL 462
C C+C GS+H +C++TG C C+ G KCD CLP + GC P C+ L
Sbjct: 379 PCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSL 438
Query: 463 CQNGGTC-LQNQRCACPRGYTGVRCEQPRCDP 493
TC ++ RC C G C+ RC P
Sbjct: 439 ----DTCDPRSGRCPCKENVEGNLCD--RCRP 464
Score = 83.2 bits (204), Expect = 5e-16
Identities = 75/315 (23%), Positives = 104/315 (33%), Gaps = 102/315 (32%)
Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSW--RAGSYLPLPHGSPNAC 344
C CN H C G C C H+T GP C +C F + +A P P +AC
Sbjct: 707 CTCNQHGT-CDPNTGI--CVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSAC 763
Query: 345 ATA--------------------------------GSFGN------CECYGH--SNRCSY 364
T G FG+ C+C G+ N
Sbjct: 764 TTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGN 823
Query: 365 IDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSA-------------------------- 398
D L+ C+ C HNT G HC+HC+ G+Y + A
Sbjct: 824 CDPLSG-HCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDP 882
Query: 399 ------------------------ELDDENVCIECNCNQIGSVHDRCN-ETGFCECREGA 433
+L C C C+ +GS D+C+ +TG C CR G
Sbjct: 883 VTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGV 942
Query: 434 AGPKCDDCLPTHYWR--QGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRC 491
G CD C + +GC C L C +N C C G+ G +C++
Sbjct: 943 TGQACDRCQLGFFGFSIKGCRACRCSP---LGAASAQCHENGTCVCRPGFEGYKCDRCHD 999
Query: 492 DPADDDGGLDCDRAP 506
+ G C + P
Sbjct: 1000 NFFLTADGTHCQQCP 1014
Score = 58.5 bits (140), Expect = 1e-08
Identities = 42/128 (32%), Positives = 49/128 (38%), Gaps = 21/128 (16%)
Query: 371 VTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGFCEC 429
V SC GQ C+ C GY R + C+ C CNQ H C+ TG C C
Sbjct: 670 VEICSCPTGYTGQFCESCAPGYKRE-MPQGGPYASCVPCTCNQ----HGTCDPNTGICVC 724
Query: 430 REGAAGPKCDDCLPTHYWR------QGCYPNVCDDDQLLCQNGGTCLQNQR---CA-CPR 479
GP C+ CLP Y C P C Q+ T + R C CP
Sbjct: 725 SHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPG-----QSACTTIPESREVVCTHCPP 779
Query: 480 GYTGVRCE 487
G G RCE
Sbjct: 780 GQRGRRCE 787
Score = 47.0 bits (110), Expect = 4e-05
Identities = 37/139 (26%), Positives = 47/139 (33%), Gaps = 24/139 (17%)
Query: 305 CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSY 364
C C TG C C ++ +P G P A C C H C
Sbjct: 673 CSCPTGYTGQFCESCAPGYKRE---------MPQGGPYASCVP-----CTCNQHGT-CDP 717
Query: 365 IDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC--NQIGSVHDRCN 422
N CV C H+T G C+ C G+Y N A D+ C C C +
Sbjct: 718 ----NTGICV-CSHHTEGPSCERCLPGFYGNPFAGQADD--CQPCPCPGQSACTTIPESR 770
Query: 423 ETGFCECREGAAGPKCDDC 441
E C G G +C+ C
Sbjct: 771 EVVCTHCPPGQRGRRCEVC 789
Score = 40.8 bits (94), Expect = 0.003
Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 16/77 (20%)
Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346
C CN +L + S +C C+ N G C +C R G++ PH +P C++
Sbjct: 430 CTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRC---------RPGTFNLQPH-NPAGCSS 479
Query: 347 AGSFGNCECYGHSNRCS 363
C CYGHS C+
Sbjct: 480 ------CFCYGHSKVCA 490
>gi|5453810 netrin 3 [Homo sapiens]
Length = 580
Score = 194 bits (494), Expect = 1e-49
Identities = 123/393 (31%), Positives = 186/393 (47%), Gaps = 50/393 (12%)
Query: 60 TCGDPPERFCSHENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPL 119
TCG P R CDAS+P AH P L+ W+S + R +PL
Sbjct: 58 TCGRPATR------------ACDASDPRRAHSPALLTSPGGTASPLCWRSESLPR--APL 103
Query: 120 EANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSA 179
+T+ K EL V + F P + L KS D+GR+W P F++ C +G
Sbjct: 104 NVTLTVPLGKAFELVF-VSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLP 162
Query: 180 RRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLES 239
A + + ++ GS + F ++D + P L L+S
Sbjct: 163 APANGPAGPGPEALCFPAPLAQPDGSGL---LAFSMQDS----SPPGL--------DLDS 207
Query: 240 AKGLKEFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSM- 298
+ L+++ T TD+R+ L RP+ G E + Y YA ++++V GRCKCN HA+ C +
Sbjct: 208 SPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVVPYSYAATDLQVGGRCKCNGHASRCLLD 267
Query: 299 REGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGH 358
+G L C+C H T GPDCG+CK + R W+ + +AC C C GH
Sbjct: 268 TQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRAT-----ARESHACLA------CSCNGH 316
Query: 359 SNRCSYIDFLNVVT-------CVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC 411
+ RC + L ++ C++C+HNT G+HC +CR G+YR+ L D C C+C
Sbjct: 317 ARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDC 376
Query: 412 NQIGSVHDRCNE-TGFCECREGAAGPKCDDCLP 443
+ +G+ CN+ TG C C++G G C+ C P
Sbjct: 377 HPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAP 409
Score = 62.8 bits (151), Expect = 8e-10
Identities = 55/185 (29%), Positives = 72/185 (38%), Gaps = 45/185 (24%)
Query: 351 GNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNG--SAELDDENVCIE 408
G C+C GH++RC +D + C C+H T G C C+ Y A + + C+
Sbjct: 253 GRCKCNGHASRC-LLDTQGHLIC-DCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLA 310
Query: 409 CNCNQIGSVHDRCN------------ETGFC-ECREGAAGPKCDDCLPTHYWRQGCY--P 453
C+CN RC G C CR AG C HY R+G Y P
Sbjct: 311 CSCNGHAR---RCRFNMELYRLSGRRSGGVCLNCRHNTAGRHC------HYCREGFYRDP 361
Query: 454 NVCDDDQLLCQN---------GGTCLQNQ-RCACPRGYTGVRCEQPRCDPADDDGGLDCD 503
D+ C+ G TC Q +C C G TG+ C RC P G
Sbjct: 362 GRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCN--RCAP-----GFQQS 414
Query: 504 RAPGA 508
R+P A
Sbjct: 415 RSPVA 419
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 189 bits (480), Expect = 5e-48
Identities = 158/521 (30%), Positives = 220/521 (42%), Gaps = 120/521 (23%)
Query: 81 CDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVELTDDVVMT 140
C A+N + AHP D G +WQS SR E N+TL + + ++
Sbjct: 106 CTAANSNKAHPASNAID----GTERWWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKF 161
Query: 141 FEYGRPTVMVLEKSLDNGRTWQPYQFYAE---DCMEAFGMSA--RRARDMSSSSAHRVLC 195
RP + VLE+S+D GRT+QP+QF+A DC+E FG R RD ++ +C
Sbjct: 162 ANSPRPDLWVLERSMDFGRTYQPWQFFASSKRDCLERFGPQTLERITRDDAA------IC 215
Query: 196 TEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMR 255
T EYSR + + V V R P N Y+ L L+EF T++R+R
Sbjct: 216 TTEYSRIVPLENGEIVVSLVNGR------PGAMNFS--YSPL-----LREFTKATNVRLR 262
Query: 256 LLRP------ALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSMREGS----LQC 305
LR +G +Y+Y+I +I + GRC C+ HA+ C ++ + LQC
Sbjct: 263 FLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHADACDAKDPTDPFRLQC 322
Query: 306 ECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSY- 364
C+HNT G C +C F + W+ P S N C + C CYGH+ C Y
Sbjct: 323 TCQHNTCGGTCDRCCPGFNQQPWK-----PATANSANECQS------CNCYGHATDCYYD 371
Query: 365 --ID-----------FLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC 411
+D + C+ C+H+T G +C+ C G+YR+ + LD +VC CNC
Sbjct: 372 PEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNC 431
Query: 412 NQIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDD----DQLL---- 462
+ C + TG C CR +G +CD C CYP +Q+L
Sbjct: 432 -ESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQ 490
Query: 463 -----CQNGGT----CLQNQ---RCACPRGYTGVRCE-----------QP---------- 489
C GT C ++ RC C + G CE QP
Sbjct: 491 IVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYGPGCQPCQCSSPGVAD 550
Query: 490 -RCDPADDDG---------GLDCDR-APGAAPRP-ATLLGC 518
RCDP D G G CDR APG P L GC
Sbjct: 551 DRCDP--DTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGC 589
Score = 81.6 bits (200), Expect = 2e-15
Identities = 70/265 (26%), Positives = 98/265 (36%), Gaps = 63/265 (23%)
Query: 276 YAISNIEVIGRCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLP 335
+ + + V RC C + + + +C C N +G C C + F S P
Sbjct: 418 HPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFP----SCYP 473
Query: 336 LPHGSPNA---CATAGSFGNCECYG---HSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCR 389
P S + AG NC+C N C V C+ CK N +G HC+ C
Sbjct: 474 TPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDP--RVGRCL-CKPNFQGTHCELCA 530
Query: 390 LGYYRNG-------SAELDDEN------------------------------VCIECNCN 412
G+Y G S + D+ +C C C+
Sbjct: 531 PGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCS 590
Query: 413 QIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDD----DQLLCQNGGT 468
G++ + C+E G C C+ AGP CD C P ++ C CD DQ LC GG
Sbjct: 591 PAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQ-LCGAGGL 649
Query: 469 CLQNQRCACPRGYTGVRCEQPRCDP 493
C C GYTG C++ C P
Sbjct: 650 ------CRCRPGYTGTACQE--CSP 666
Score = 74.3 bits (181), Expect = 3e-13
Identities = 66/229 (28%), Positives = 90/229 (39%), Gaps = 49/229 (21%)
Query: 290 NLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGS 349
N A C +R G QC C+ G C +C F PL GS S
Sbjct: 1922 NNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGN--------PLVLGS--------S 1965
Query: 350 FGNCECYGHSNRCSYIDFLNVVT--CVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCI 407
C+C G+ + + +T C C +T G C+ C G+Y G+A L C
Sbjct: 1966 CQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFY--GNALLPGN--CT 2021
Query: 408 ECNCNQIGSVHDRCN-ETGFCECREGAAGPKCDDCLPTHYWRQ---GCYPNVC------- 456
C+C G+ + C+ +G C C+ G G +CD C H+ GC P C
Sbjct: 2022 RCDCTPCGT--EACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGS 2079
Query: 457 ----DDDQLLCQNGGTCLQNQRCACPRGYTGV------RCEQP--RCDP 493
Q C+ G Q + CA GY G+ RC+ P RCDP
Sbjct: 2080 ECHPQSGQCHCRPGTMGPQCRECA--PGYWGLPEQGCRRCQCPGGRCDP 2126
Score = 72.0 bits (175), Expect = 1e-12
Identities = 56/221 (25%), Positives = 81/221 (36%), Gaps = 41/221 (18%)
Query: 284 IGRCKCN-----LHANLCS---MREGSLQCECEH-----NTTGPDCGKCKKNF----RTR 326
+GRC C H LC+ G C+C + PD G+C+ T
Sbjct: 512 VGRCLCKPNFQGTHCELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATC 571
Query: 327 SWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQ 386
A Y P C+ AG+ E + RC C+ G HC
Sbjct: 572 DRCAPGYFHFPLCQLCGCSPAGTLP--EGCDEAGRCL------------CQPEFAGPHCD 617
Query: 387 HCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHY 446
CR GY+ + C C C+ G++ C G C CR G G C +C P +
Sbjct: 618 RCRPGYHGFPN--------CQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFH 669
Query: 447 WRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCE 487
C P C + L + ++ +C+C TG+RC+
Sbjct: 670 GFPSCVPCHCSAEGSL--HAACDPRSGQCSCRPRVTGLRCD 708
Score = 69.7 bits (169), Expect = 6e-12
Identities = 56/196 (28%), Positives = 75/196 (38%), Gaps = 35/196 (17%)
Query: 305 CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSY 364
C C + G C +C F +R L L P C+C+GHS+RC
Sbjct: 1831 CLCPASYRGDSCQECAPGF----YRDVKGLFLGRCVP-----------CQCHGHSDRC-- 1873
Query: 365 IDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN---QIGSVHDRC 421
CV C+HNT G HC+ C+ G+ S+ D C+ C C + + C
Sbjct: 1874 --LPGSGVCVDCQHNTEGAHCERCQAGFV---SSRDDPSAPCVSCPCPLSVPSNNFAEGC 1928
Query: 422 NETG---FCECREGAAGPKCDDCLPTHYWR-----QGCYPNVC--DDDQLLCQNGGTCLQ 471
G C C+ G AG C+ C P + C P C + D L + L
Sbjct: 1929 VLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLT 1988
Query: 472 NQRCACPRGYTGVRCE 487
C R TG RCE
Sbjct: 1989 GACRGCLRHTTGPRCE 2004
Score = 62.4 bits (150), Expect = 1e-09
Identities = 43/153 (28%), Positives = 60/153 (39%), Gaps = 24/153 (15%)
Query: 297 SMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPN-ACATAGSFGN-CE 354
++ E + C C + GP C +CK F W G P G +C G+ G E
Sbjct: 736 ALPEAQVPCMCRAHVEGPSCDRCKPGF----W--GLSPSNPEGCTRCSCDLRGTLGGVAE 789
Query: 355 CYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQI 414
C + +C CK + GQ C C+ G++ A D C C C+
Sbjct: 790 CQPGTGQC------------FCKPHVCGQACASCKDGFFGLDQA---DYFGCRSCRCDIG 834
Query: 415 GSVHDRCN-ETGFCECREGAAGPKCDDCLPTHY 446
G++ C TG C CR GP C + HY
Sbjct: 835 GALGQSCEPRTGVCRCRPNTQGPTCSEPARDHY 867
Score = 57.8 bits (138), Expect = 2e-08
Identities = 45/160 (28%), Positives = 57/160 (35%), Gaps = 40/160 (25%)
Query: 289 CNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAG 348
C+ A LC G QC C T PDC C+ P G C
Sbjct: 1484 CDCGARLCDELTG--QCICPPRTIPPDCLLCQ--------------PQTFG----CHPLV 1523
Query: 349 SFGNCECYGHSNRCSYIDFLNVVTC------VSCKHNTRGQHCQHCRLGYYRNGSAELDD 402
C C G I L TC C+ N G+ C C G++
Sbjct: 1524 GCEECNCSGPG-----IQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPR----- 1573
Query: 403 ENVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDC 441
C C+C++ G+ C+ TG C C+E GPKCD C
Sbjct: 1574 ---CRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQC 1610
Score = 53.5 bits (127), Expect = 5e-07
Identities = 42/162 (25%), Positives = 56/162 (34%), Gaps = 36/162 (22%)
Query: 286 RCKCN-LHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 344
RC C C G C C+ TG C +C++ G + G C
Sbjct: 2022 RCDCTPCGTEACDPHSG--HCLCKAGVTGRRCDRCQE---------GHFGFDGCGGCRPC 2070
Query: 345 ATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDEN 404
A + EC+ S +C C+ T G C+ C GY+ E
Sbjct: 2071 ACGPAAEGSECHPQSGQCH------------CRPGTMGPQCRECAPGYWGL------PEQ 2112
Query: 405 VCIECNCNQIGSVHDRCN-ETGFCECREGAAGPKCDDCLPTH 445
C C C RC+ TG C C G +G +CD C H
Sbjct: 2113 GCRRCQCPG-----GRCDPHTGRCNCPPGLSGERCDTCSQQH 2149
Score = 50.8 bits (120), Expect = 3e-06
Identities = 52/195 (26%), Positives = 69/195 (35%), Gaps = 51/195 (26%)
Query: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCS 363
QC C + G DC +C A Y P+ P C G C + +C
Sbjct: 1456 QCPCHAHVIGRDCSRC----------ATGYWGFPNCRPCDC------GARLCDELTGQCI 1499
Query: 364 YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGS---VHDR 420
C+ C+ T G C H +G C ECNC+ G
Sbjct: 1500 CPPRTIPPDCLLCQPQTFG--C-HPLVG--------------CEECNCSGPGIQELTDPT 1542
Query: 421 CN-ETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC------LQNQ 473
C+ ++G C+CR G +CD C P + C P CD C GT L Q
Sbjct: 1543 CDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRP--CD-----CHEAGTAPGVCDPLTGQ 1595
Query: 474 RCACPRGYTGVRCEQ 488
C C G +C+Q
Sbjct: 1596 -CYCKENVQGPKCDQ 1609
Score = 38.9 bits (89), Expect = 0.012
Identities = 32/123 (26%), Positives = 43/123 (34%), Gaps = 29/123 (23%)
Query: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCS 363
QC+C N TG C C F HG P C+C+
Sbjct: 1549 QCKCRPNVTGRRCDTCSPGF--------------HGYPRCRP-------CDCHEAGTAPG 1587
Query: 364 YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE 423
D L C CK N +G C C LG + S + + C C C G+ +RC
Sbjct: 1588 VCDPLTG-QCY-CKENVQGPKCDQCSLGTF---SLDAANPKGCTRCFC--FGAT-ERCRS 1639
Query: 424 TGF 426
+ +
Sbjct: 1640 SSY 1642
Score = 38.5 bits (88), Expect = 0.015
Identities = 29/115 (25%), Positives = 36/115 (31%), Gaps = 27/115 (23%)
Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346
C C A S QC C T GP C +C A Y LP C
Sbjct: 2070 CACGPAAEGSECHPQSGQCHCRPGTMGPQCREC----------APGYWGLPEQGCRRCQC 2119
Query: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCK-------------HNTRGQHCQHC 388
G C H+ RC+ L+ C +C H+ + C HC
Sbjct: 2120 PGG----RCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHC 2170
Score = 35.8 bits (81), Expect = 0.100
Identities = 24/90 (26%), Positives = 33/90 (36%), Gaps = 10/90 (11%)
Query: 392 YYRNGSAELD--DENVCIECNCNQIGSVHDRCNETGF-CECREGAAGPKCDDCLPTHYWR 448
+ RN +A L N C C+++G+ C G C C G C C ++
Sbjct: 1419 FCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGF 1478
Query: 449 QGCYPNVCDDDQLLCQNGGTCLQNQRCACP 478
C P CD LC +C CP
Sbjct: 1479 PNCRP--CDCGARLCDE-----LTGQCICP 1501
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 169 bits (427), Expect = 8e-42
Identities = 125/454 (27%), Positives = 193/454 (42%), Gaps = 78/454 (17%)
Query: 81 CDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVELTDDVVMT 140
C++ +P AHP D E +WQS S N+TL + + ++
Sbjct: 105 CNSEDPRKAHPVTNAIDGSER----WWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKF 160
Query: 141 FEYGRPTVMVLEKSLDNGRTWQPYQFYAE---DCMEAFGMSARRARDMSSSSAHRVLCTE 197
RP + VLE+S+D G T+ P+Q++A DC++ FG A +M+ + VLC
Sbjct: 161 ANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREA----NMAVTRDDDVLCVT 216
Query: 198 EYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMRLL 257
EYSR + + V + R P +N +T L+EF T++R+R L
Sbjct: 217 EYSRIVPLENGEVVVSLINGR------PGAKNFTFSHT-------LREFTKATNIRLRFL 263
Query: 258 RP-ALGGTYVQREN-----LYKYFYAISNIEVIGRCKCNLHANLCSMR--EGSLQCECEH 309
R L G + + +Y+Y+I +I + G+C CN HA +C++ E +CEC+H
Sbjct: 264 RTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQH 323
Query: 310 NTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYID--- 366
+T G C +C + R WR P A + C C+GH++ C Y
Sbjct: 324 HTCGETCDRCCTGYNQRRWR-----------PAAWEQSHECEACNCHGHASNCYYDPDVE 372
Query: 367 -----------FLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIG 415
+ C++C+HNT G +C+ C GYYR +D + CI C+C+
Sbjct: 373 RQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEH 432
Query: 416 SVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCY--------------PNVCDDDQ 460
+ D C + +G C C+ G C+ C +Y C P D
Sbjct: 433 A--DGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKG 490
Query: 461 LLCQNGGT----CLQNQRCACPRGYTGVRCEQPR 490
C G C + RC C G G RC+ R
Sbjct: 491 CDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCR 524
Score = 79.3 bits (194), Expect = 8e-15
Identities = 64/243 (26%), Positives = 93/243 (38%), Gaps = 71/243 (29%)
Query: 287 CKCNLHANLC------SMREGSLQCE-----------CEHNTTGPDCGKCKKNFRTRSWR 329
C C+ HA+ C ++ SL + C+HNT G +C +C K
Sbjct: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAK-------- 407
Query: 330 AGSYLP--LPHGSPNACATAGSFGNCE------CYGHSNRCSYIDFLNVVTCVSCKHNTR 381
G Y P +P +P+ C +C+ C S RC CK N
Sbjct: 408 -GYYRPYGVPVDAPDGCIPC----SCDPEHADGCEQGSGRCH------------CKPNFH 450
Query: 382 GQHCQHCRLGYYR-------------NGSAELDDENVCIECNCNQIGSVHDRCNETGFCE 428
G +C+ C +GYY S+E C+CN G + + C+ G C
Sbjct: 451 GDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCL 510
Query: 429 CREGAAGPKCDDCLPTHY---WRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVR 485
CR G GP+CD C Y Q C+ + Q+ C + +C C G TG R
Sbjct: 511 CRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSS-----VTGQCECRPGVTGQR 565
Query: 486 CEQ 488
C++
Sbjct: 566 CDR 568
Score = 74.7 bits (182), Expect = 2e-13
Identities = 53/179 (29%), Positives = 71/179 (39%), Gaps = 26/179 (14%)
Query: 353 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412
C C GHSN+C D + CV+C+HNT G+HC+ C+ GYY N C C C
Sbjct: 1687 CNCNGHSNQCQ--DGSGI--CVNCQHNTAGEHCERCQEGYYGNAV-----HGSCRACPCP 1737
Query: 413 QIGSVHDRCNETG---FCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC 469
S C G C C+ G G +C+ C P ++ + C C +C
Sbjct: 1738 HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP----C----SC 1789
Query: 470 LQNQRCACPRGYTGVRCEQPRCDPADDDGGLDCDRAPGAAPRPATLLGCLLLLGLAARL 528
N + TG Q +P D +CD TLL L +G RL
Sbjct: 1790 NSNGQLGSCHPLTGDCINQ---EPKDSSPAEECDDCDSCV---MTLLNDLATMGEQLRL 1842
Score = 71.2 bits (173), Expect = 2e-12
Identities = 59/207 (28%), Positives = 84/207 (40%), Gaps = 25/207 (12%)
Query: 287 CKCNL-HANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPL-PHGSPNA- 343
C C+ HA+ C +GS +C C+ N G +C KC + + +P+ P +P++
Sbjct: 426 CSCDPEHADGCE--QGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLR--IPIFPVSTPSSE 481
Query: 344 CATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDE 403
AG C+C D C+ C+ G C CR G+Y
Sbjct: 482 DPVAGDIKGCDCNLEGVLPEICDAHG--RCL-CRPGVEGPRCDTCRSGFY--------SF 530
Query: 404 NVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLL 462
+C C C+ +GS C+ TG CECR G G +CD CL Y +P+ C
Sbjct: 531 PICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAY----DFPH-CQGSSSA 585
Query: 463 CQNGGTCLQN-QRCACPRGYTGVRCEQ 488
C GT N C C G C +
Sbjct: 586 CDPAGTINSNLGYCQCKLHVEGPTCSR 612
Score = 69.3 bits (168), Expect = 8e-12
Identities = 51/162 (31%), Positives = 67/162 (41%), Gaps = 33/162 (20%)
Query: 287 CKCNLHANLCSMREGSLQC-ECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACA 345
C CN H+N C ++GS C C+HNT G C +C++ G Y HGS AC
Sbjct: 1687 CNCNGHSNQC--QDGSGICVNCQHNTAGEHCERCQE---------GYYGNAVHGSCRACP 1735
Query: 346 T--AGSFG-NCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDD 402
SF C G RC SCK G C+ C GY+ N
Sbjct: 1736 CPHTNSFATGCVVNGGDVRC------------SCKAGYTGTQCERCAPGYFGNPQ---KF 1780
Query: 403 ENVCIECNCN---QIGSVHDRCNETGFCECREGAAGPKCDDC 441
C C+CN Q+GS H + E ++ + +CDDC
Sbjct: 1781 GGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 66.2 bits (160), Expect = 7e-11
Identities = 59/237 (24%), Positives = 89/237 (37%), Gaps = 44/237 (18%)
Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRT-----RSWRA--GSY-LPL-- 336
C CNL L + + +C C GP C C+ F + W + GSY +P
Sbjct: 491 CDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSS 550
Query: 337 --------PHGSPNAC--ATAGSFGNCECYGHSNRCSYIDFLNV-VTCVSCKHNTRGQHC 385
P + C +G++ C G S+ C +N + CK + G C
Sbjct: 551 VTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTC 610
Query: 386 QHCRLGYYRNGSAELDDENV--CIECNCNQIGSVHD--RCNE-TGFCECREGAAGPKCDD 440
C+L Y+ LD EN C EC C++ G+V C + G C C+ G CD
Sbjct: 611 SRCKLLYWN-----LDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDT 665
Query: 441 C--------LPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQP 489
C ++ QGC ++ +C + C C G C++P
Sbjct: 666 CEDGYFALEKSNYFGCQGCQCDIGGALSSMCSG-----PSGVCQCREHVVGKVCQRP 717
Score = 58.9 bits (141), Expect = 1e-08
Identities = 42/133 (31%), Positives = 55/133 (41%), Gaps = 22/133 (16%)
Query: 371 VTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFC-EC 429
V +C G CQ C GYYR+ C+ CNCN G + + +G C C
Sbjct: 1651 VEICACPPAYAGDSCQGCSPGYYRDHKGLYTGR--CVPCNCN--GHSNQCQDGSGICVNC 1706
Query: 430 REGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGT------CLQN---QRCACPRG 480
+ AG C+ C ++G Y N C T C+ N RC+C G
Sbjct: 1707 QHNTAGEHCERC------QEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAG 1760
Query: 481 YTGVRCEQPRCDP 493
YTG +CE RC P
Sbjct: 1761 YTGTQCE--RCAP 1771
Score = 51.6 bits (122), Expect = 2e-06
Identities = 58/238 (24%), Positives = 81/238 (34%), Gaps = 51/238 (21%)
Query: 287 CKCNLHANLCSMREGSLQCECEHN-TTGPDCGK------CKKNFRTRSWR--AGSYLPLP 337
CK + + + +G+L CEC TGP C C+ N R A + P
Sbjct: 1248 CKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP 1307
Query: 338 HGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGS 397
P +C G C + +C C T C+ C S
Sbjct: 1308 RCKPCSC------GRRLCEEMTGQCR------------CPPRTVRPQCEVCE-----THS 1344
Query: 398 AELDDENVCIECNCNQIGSVH---DRCN-ETGFCECREGAAGPKCDDCLPTHYWRQGCYP 453
C CNC++ G++ C+ ++G C C+ G +CD C Y C P
Sbjct: 1345 FSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVP 1404
Query: 454 NVCDDDQL---LCQNG-GTCLQNQRCACPRGYTGVRCEQPR-----CDPADDDGGLDC 502
C+ D +C G G CL C G C R DPA+ G C
Sbjct: 1405 CNCNRDGTEPGVCDPGTGACL------CKENVEGTECNVCREGSFHLDPANLKGCTSC 1456
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 169 bits (427), Expect = 8e-42
Identities = 125/454 (27%), Positives = 193/454 (42%), Gaps = 78/454 (17%)
Query: 81 CDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVELTDDVVMT 140
C++ +P AHP D E +WQS S N+TL + + ++
Sbjct: 105 CNSEDPRKAHPVTNAIDGSER----WWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKF 160
Query: 141 FEYGRPTVMVLEKSLDNGRTWQPYQFYAE---DCMEAFGMSARRARDMSSSSAHRVLCTE 197
RP + VLE+S+D G T+ P+Q++A DC++ FG A +M+ + VLC
Sbjct: 161 ANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREA----NMAVTRDDDVLCVT 216
Query: 198 EYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMRLL 257
EYSR + + V + R P +N +T L+EF T++R+R L
Sbjct: 217 EYSRIVPLENGEVVVSLINGR------PGAKNFTFSHT-------LREFTKATNIRLRFL 263
Query: 258 RP-ALGGTYVQREN-----LYKYFYAISNIEVIGRCKCNLHANLCSMR--EGSLQCECEH 309
R L G + + +Y+Y+I +I + G+C CN HA +C++ E +CEC+H
Sbjct: 264 RTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQH 323
Query: 310 NTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYID--- 366
+T G C +C + R WR P A + C C+GH++ C Y
Sbjct: 324 HTCGETCDRCCTGYNQRRWR-----------PAAWEQSHECEACNCHGHASNCYYDPDVE 372
Query: 367 -----------FLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIG 415
+ C++C+HNT G +C+ C GYYR +D + CI C+C+
Sbjct: 373 RQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEH 432
Query: 416 SVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCY--------------PNVCDDDQ 460
+ D C + +G C C+ G C+ C +Y C P D
Sbjct: 433 A--DGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKG 490
Query: 461 LLCQNGGT----CLQNQRCACPRGYTGVRCEQPR 490
C G C + RC C G G RC+ R
Sbjct: 491 CDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCR 524
Score = 79.3 bits (194), Expect = 8e-15
Identities = 64/243 (26%), Positives = 93/243 (38%), Gaps = 71/243 (29%)
Query: 287 CKCNLHANLC------SMREGSLQCE-----------CEHNTTGPDCGKCKKNFRTRSWR 329
C C+ HA+ C ++ SL + C+HNT G +C +C K
Sbjct: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAK-------- 407
Query: 330 AGSYLP--LPHGSPNACATAGSFGNCE------CYGHSNRCSYIDFLNVVTCVSCKHNTR 381
G Y P +P +P+ C +C+ C S RC CK N
Sbjct: 408 -GYYRPYGVPVDAPDGCIPC----SCDPEHADGCEQGSGRCH------------CKPNFH 450
Query: 382 GQHCQHCRLGYYR-------------NGSAELDDENVCIECNCNQIGSVHDRCNETGFCE 428
G +C+ C +GYY S+E C+CN G + + C+ G C
Sbjct: 451 GDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCL 510
Query: 429 CREGAAGPKCDDCLPTHY---WRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVR 485
CR G GP+CD C Y Q C+ + Q+ C + +C C G TG R
Sbjct: 511 CRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSS-----VTGQCECRPGVTGQR 565
Query: 486 CEQ 488
C++
Sbjct: 566 CDR 568
Score = 74.7 bits (182), Expect = 2e-13
Identities = 53/179 (29%), Positives = 71/179 (39%), Gaps = 26/179 (14%)
Query: 353 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412
C C GHSN+C D + CV+C+HNT G+HC+ C+ GYY N C C C
Sbjct: 1687 CNCNGHSNQCQ--DGSGI--CVNCQHNTAGEHCERCQEGYYGNAV-----HGSCRACPCP 1737
Query: 413 QIGSVHDRCNETG---FCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC 469
S C G C C+ G G +C+ C P ++ + C C +C
Sbjct: 1738 HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP----C----SC 1789
Query: 470 LQNQRCACPRGYTGVRCEQPRCDPADDDGGLDCDRAPGAAPRPATLLGCLLLLGLAARL 528
N + TG Q +P D +CD TLL L +G RL
Sbjct: 1790 NSNGQLGSCHPLTGDCINQ---EPKDSSPAEECDDCDSCV---MTLLNDLATMGEQLRL 1842
Score = 71.2 bits (173), Expect = 2e-12
Identities = 59/207 (28%), Positives = 84/207 (40%), Gaps = 25/207 (12%)
Query: 287 CKCNL-HANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPL-PHGSPNA- 343
C C+ HA+ C +GS +C C+ N G +C KC + + +P+ P +P++
Sbjct: 426 CSCDPEHADGCE--QGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLR--IPIFPVSTPSSE 481
Query: 344 CATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDE 403
AG C+C D C+ C+ G C CR G+Y
Sbjct: 482 DPVAGDIKGCDCNLEGVLPEICDAHG--RCL-CRPGVEGPRCDTCRSGFY--------SF 530
Query: 404 NVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLL 462
+C C C+ +GS C+ TG CECR G G +CD CL Y +P+ C
Sbjct: 531 PICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAY----DFPH-CQGSSSA 585
Query: 463 CQNGGTCLQN-QRCACPRGYTGVRCEQ 488
C GT N C C G C +
Sbjct: 586 CDPAGTINSNLGYCQCKLHVEGPTCSR 612
Score = 69.3 bits (168), Expect = 8e-12
Identities = 51/162 (31%), Positives = 67/162 (41%), Gaps = 33/162 (20%)
Query: 287 CKCNLHANLCSMREGSLQC-ECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACA 345
C CN H+N C ++GS C C+HNT G C +C++ G Y HGS AC
Sbjct: 1687 CNCNGHSNQC--QDGSGICVNCQHNTAGEHCERCQE---------GYYGNAVHGSCRACP 1735
Query: 346 T--AGSFG-NCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDD 402
SF C G RC SCK G C+ C GY+ N
Sbjct: 1736 CPHTNSFATGCVVNGGDVRC------------SCKAGYTGTQCERCAPGYFGNPQ---KF 1780
Query: 403 ENVCIECNCN---QIGSVHDRCNETGFCECREGAAGPKCDDC 441
C C+CN Q+GS H + E ++ + +CDDC
Sbjct: 1781 GGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 66.2 bits (160), Expect = 7e-11
Identities = 59/237 (24%), Positives = 89/237 (37%), Gaps = 44/237 (18%)
Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRT-----RSWRA--GSY-LPL-- 336
C CNL L + + +C C GP C C+ F + W + GSY +P
Sbjct: 491 CDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSS 550
Query: 337 --------PHGSPNAC--ATAGSFGNCECYGHSNRCSYIDFLNV-VTCVSCKHNTRGQHC 385
P + C +G++ C G S+ C +N + CK + G C
Sbjct: 551 VTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTC 610
Query: 386 QHCRLGYYRNGSAELDDENV--CIECNCNQIGSVHD--RCNE-TGFCECREGAAGPKCDD 440
C+L Y+ LD EN C EC C++ G+V C + G C C+ G CD
Sbjct: 611 SRCKLLYWN-----LDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDT 665
Query: 441 C--------LPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQP 489
C ++ QGC ++ +C + C C G C++P
Sbjct: 666 CEDGYFALEKSNYFGCQGCQCDIGGALSSMCSG-----PSGVCQCREHVVGKVCQRP 717
Score = 58.9 bits (141), Expect = 1e-08
Identities = 42/133 (31%), Positives = 55/133 (41%), Gaps = 22/133 (16%)
Query: 371 VTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFC-EC 429
V +C G CQ C GYYR+ C+ CNCN G + + +G C C
Sbjct: 1651 VEICACPPAYAGDSCQGCSPGYYRDHKGLYTGR--CVPCNCN--GHSNQCQDGSGICVNC 1706
Query: 430 REGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGT------CLQN---QRCACPRG 480
+ AG C+ C ++G Y N C T C+ N RC+C G
Sbjct: 1707 QHNTAGEHCERC------QEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAG 1760
Query: 481 YTGVRCEQPRCDP 493
YTG +CE RC P
Sbjct: 1761 YTGTQCE--RCAP 1771
Score = 51.6 bits (122), Expect = 2e-06
Identities = 58/238 (24%), Positives = 81/238 (34%), Gaps = 51/238 (21%)
Query: 287 CKCNLHANLCSMREGSLQCECEHN-TTGPDCGK------CKKNFRTRSWR--AGSYLPLP 337
CK + + + +G+L CEC TGP C C+ N R A + P
Sbjct: 1248 CKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP 1307
Query: 338 HGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGS 397
P +C G C + +C C T C+ C S
Sbjct: 1308 RCKPCSC------GRRLCEEMTGQCR------------CPPRTVRPQCEVCE-----THS 1344
Query: 398 AELDDENVCIECNCNQIGSVH---DRCN-ETGFCECREGAAGPKCDDCLPTHYWRQGCYP 453
C CNC++ G++ C+ ++G C C+ G +CD C Y C P
Sbjct: 1345 FSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVP 1404
Query: 454 NVCDDDQL---LCQNG-GTCLQNQRCACPRGYTGVRCEQPR-----CDPADDDGGLDC 502
C+ D +C G G CL C G C R DPA+ G C
Sbjct: 1405 CNCNRDGTEPGVCDPGTGACL------CKENVEGTECNVCREGSFHLDPANLKGCTSC 1456
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 167 bits (423), Expect = 2e-41
Identities = 116/392 (29%), Positives = 180/392 (45%), Gaps = 72/392 (18%)
Query: 137 VVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAF-GMSARRARDMSSSSAHRVLC 195
+++TF+ RP M++E+S D G W+ ++++A+DC +F +++ +A+ + ++C
Sbjct: 129 LILTFKTFRPAAMLVERSTDYGHNWKVFKYFAKDCATSFPNITSGQAQGVGD-----IVC 183
Query: 196 TEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMR 255
+YS S + V + F I +N Y+ +++ TLT+LR+
Sbjct: 184 DSKYSDIEPSTGGEVVLKVLDPSFEI---------ENPYSPY-----IQDLVTLTNLRIN 229
Query: 256 LLR-PALGGTYV---QRENLYKYFYAISNIEVIGRCKCNLHANLCSMRE---GSL----- 303
+ LG + Q ++L KY+YA+ + V G C CN HA+ C + G +
Sbjct: 230 FTKLHTLGDALLGRRQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPG 289
Query: 304 ----QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHS 359
QC C+HNT GP+C +CK F+ WR + L NAC + C C HS
Sbjct: 290 MVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADL-----QDNACRS------CSCNSHS 338
Query: 360 NRCSY-------IDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412
+RC + L+ C C+HNT GQHC CR +YR+ + D CI C C+
Sbjct: 339 SRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECD 398
Query: 413 QIGSVHDRC----------NETGFCECREGAAGPKCDDCLPTHYWRQ-----GCYPNVCD 457
G++ + G C C+E G KCD C P HY GC P CD
Sbjct: 399 PDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQP--CD 456
Query: 458 DDQLLCQNGGTC-LQNQRCACPRGYTGVRCEQ 488
+ L TC + +C C TG CE+
Sbjct: 457 CNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE 488
Score = 69.3 bits (168), Expect = 8e-12
Identities = 59/198 (29%), Positives = 80/198 (40%), Gaps = 41/198 (20%)
Query: 287 CKCNLHANL-----CSMREGSLQCECEHNTTGPDCGKCK---------KNFRTRSWRAGS 332
C CN + ++ CS G C HNT G +C CK + R S A
Sbjct: 970 CACNNNIDVTDPESCSRVTGEC-LRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASG 1028
Query: 333 YLPL--PHGSPNACATAGSFGNCECYGH-----SNRCS--YIDFLNVVTCVSCKHNTR-- 381
P+ P G AC G C C + +RC+ Y + + C SC + R
Sbjct: 1029 VSPMECPPGG-GACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTS 1087
Query: 382 -GQHCQH------CRLGYYRNGSAEL------DDENVCIECNCNQIGSVHDRCN-ETGFC 427
HC C+LGY +E D CI C+CN+ G+ C+ +TG C
Sbjct: 1088 QSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMC 1147
Query: 428 ECREGAAGPKCDDCLPTH 445
CREG +G +CD C H
Sbjct: 1148 RCREGVSGQRCDRCARGH 1165
Score = 56.6 bits (135), Expect = 5e-08
Identities = 38/146 (26%), Positives = 60/146 (41%), Gaps = 24/146 (16%)
Query: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHG-SPNACATAGSFGNCECYGHSNRC 362
QC C+ N G C +CK N G P G P C GS C + +C
Sbjct: 422 QCLCKENVEGAKCDQCKPN------HYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQC 475
Query: 363 SYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN 422
+ ++ G HC+ C +GY+ G + + C C+C+ G+ + C+
Sbjct: 476 LCLSYVT------------GAHCEECTVGYWGLG----NHLHGCSPCDCDIGGAYSNVCS 519
Query: 423 -ETGFCECREGAAGPKCDDCLPTHYW 447
+ G CECR G C + P +++
Sbjct: 520 PKNGQCECRPHVTGRSCSEPAPGYFF 545
Score = 55.8 bits (133), Expect = 9e-08
Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 15/127 (11%)
Query: 376 CKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE-TGFCECREGAA 434
CK G+ C C G Y G + C C+C+ GS C++ TG C C +
Sbjct: 790 CKPLVVGRCCDRCSTGSYDLG------HHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVS 843
Query: 435 GPKCDDCLPTHYWRQGCYP-------NVCDDDQLLCQNGGTCLQNQRC-ACPRGYTGVRC 486
G +CD CL ++ C+P +CD + C N G + C C GY G
Sbjct: 844 GRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPS 903
Query: 487 EQPRCDP 493
C P
Sbjct: 904 SGQPCRP 910
Score = 50.8 bits (120), Expect = 3e-06
Identities = 73/300 (24%), Positives = 97/300 (32%), Gaps = 93/300 (31%)
Query: 287 CKCNLHANL---CSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGS-PN 342
CKC+ ++ CS G QC+C+ G C +C GSY HG P
Sbjct: 769 CKCHPQGSVGSSCSRLGG--QCQCKPLVVGRCCDRCS---------TGSYDLGHHGCHPC 817
Query: 343 ACATAGS--------FGNCECYGH-----SNRC--SYIDFLN----------------VV 371
C GS G C C+G +RC Y F +
Sbjct: 818 HCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETG 877
Query: 372 TCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC------NQI---GSVHDRCN 422
+C +C T G++C+ C GYY N S+ C C C NQ + +
Sbjct: 878 SCFNCGGFTTGRNCERCIDGYYGNPSS----GQPCRPCLCPDDPSSNQYFAHSCYQNLWS 933
Query: 423 ETGFCECREGAAGPKCDDCLPTHYWR-----QGCYPNVCD------DDQLLCQNGGTCL- 470
C C +G G +C +C Y C P C+ D + + G CL
Sbjct: 934 SDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLR 993
Query: 471 -----QNQRC-ACPRGYTGVRCEQP--------------RCDPADDDGGLDCDRAPGAAP 510
Q C C G+ G Q C P G CD GA P
Sbjct: 994 CLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPG--GGACLCDPVTGACP 1051
Score = 42.4 bits (98), Expect = 0.001
Identities = 36/110 (32%), Positives = 45/110 (40%), Gaps = 19/110 (17%)
Query: 397 SAELDDENVCIECNCNQIGSVHDRCNET-GFCECREGAAGPKCDDCLPTHY--WRQGCYP 453
SA+L D V C C+ GSV C+ G C+C+ G CD C Y GC+P
Sbjct: 759 SAKLHDGAVA--CKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHP 816
Query: 454 NVC----DDDQLLCQNGGTC-----LQNQRC-ACPRGYTGVRCEQPRCDP 493
C D + Q G C + +RC C GY G P C P
Sbjct: 817 CHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGF----PSCHP 862
>gi|93204871 netrin 4 [Homo sapiens]
Length = 628
Score = 162 bits (410), Expect = 7e-40
Identities = 141/464 (30%), Positives = 201/464 (43%), Gaps = 90/464 (19%)
Query: 38 ACQPKVMRLKDYVKVKVEPSGITCG-DPPERFCSH-ENPYLCSNE-----CDASNPDLAH 90
AC P++ L K+ + TCG + E +C + EN L + C+A+ P LAH
Sbjct: 33 ACNPRMGNLALGRKLWADT---TCGQNATELYCFYSENTDLTCRQPKCDKCNAAYPHLAH 89
Query: 91 PPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVELTDDVVMTFEYGRPTVMV 150
P M D T+WQS I L T +VM F+ RP MV
Sbjct: 90 LPSAMADSSFRFPRTWWQSAE-----DVHREKIQLDLEAEFYFTHLIVM-FKSPRPAAMV 143
Query: 151 LEKSLDNGRTWQPYQFYAEDCMEAFGMSARRARDMSSSSAHRVLCTEEYSRWAGSKKEKH 210
L++S D G+TW+PY+++A +C FG+ D+ A +CT +YS
Sbjct: 144 LDRSQDFGKTWKPYKYFATNCSATFGLED----DVVKKGA---ICTSKYSS--------- 187
Query: 211 VRFEVRDRFAIF-AGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMRLLRPALGGTYVQRE 269
F IF A + +N Y SAK ++E +T+LR++LL+ QR
Sbjct: 188 -PFPCTGGEVIFKALSPPYDTENPY----SAK-VQEQLKITNLRVQLLKRQ--SCPCQRN 239
Query: 270 NLYKY-----FYAISNIEVIGRCKCNLHANLCSMREGSL-------------QCECEHNT 311
+L + YAI + V G C CN HA+ C G +C C+HNT
Sbjct: 240 DLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNT 299
Query: 312 TGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVV 371
G C C + R W A G+PN C T C+C GH++ C + +NV
Sbjct: 300 AGSHCQHCAPLYNDRPWEAADGKT---GAPNECRT------CKCNGHADTCHFD--VNVW 348
Query: 372 ---------TCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN 422
C C+HNT GQ+CQ C+ G+YR+ + C C+C+ +GS N
Sbjct: 349 EASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPAN 408
Query: 423 ETGFCE-------CREGAAGPKCDDCLPTHYW---RQGCYPNVC 456
FC+ C+ G AG +CD C+ YW GC P C
Sbjct: 409 SVTFCDPSNGDCPCKPGVAGRRCDRCM-VGYWGFGDYGCRPCDC 451
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 158 bits (400), Expect = 1e-38
Identities = 148/506 (29%), Positives = 213/506 (42%), Gaps = 91/506 (17%)
Query: 60 TCG-DPPERFC--SH----ENPYLCSNECDASNPDLAHPPRL---MFDKEEEGLATYWQS 109
TCG + P+ +C SH + +LC + S D H R+ + + A +WQS
Sbjct: 67 TCGLNGPQPYCIVSHLQDEKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRRAAWWQS 126
Query: 110 ITWSRYPSPLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAE 169
+ P+ I L T ++MTF+ RP M++E+S D GRTW Y++++
Sbjct: 127 E--NGIPA---VTIQLDLEAEFHFTH-LIMTFKTFRPAAMLVERSADFGRTWHVYRYFSY 180
Query: 170 DCMEAF-GMSARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLR 228
DC F G+ R V+C YS S E V + V D P
Sbjct: 181 DCGADFPGVPLAPPRHWDD-----VVCESRYSEIEPST-EGEVIYRVLDPAIPIPDPYSS 234
Query: 229 NMDNLYTRLESAKGLKEFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCK 288
+ NL L TL D LL P +RE KY+YA+ + V G C
Sbjct: 235 RIQNLLKITNLRVNLTRLHTLGD---NLLDP-------RREIREKYYYALYELVVRGNCF 284
Query: 289 CNLHANLCSMREGSLQ---------CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHG 339
C HA+ C+ G+ C C+HNT G +C +C+ +R WR P G
Sbjct: 285 CYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWR-----PAEDG 339
Query: 340 SPNACATAGSFGNCECYGHSNRCS-----YIDFLNVV--TCVSCKHNTRGQHCQHCRLGY 392
+AC CEC+GH++ C Y+ NV C C+HNT G+HC+ CR +
Sbjct: 340 HSHACR------KCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFF 393
Query: 393 YRNGSAELDDENVCIECNCNQIGSVH-DRCNE---------TGFCECREGAAGPKCDDCL 442
YR+ + +L D VC C+C+ +GS RC+ +G C C+E G +C C
Sbjct: 394 YRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCR 453
Query: 443 PTHYW-----RQGCYPNVCD-----DDQLLCQ-NGGTC-----LQNQRC-ACPRGYTGVR 485
+ R GC C+ C N G+C + + C C G+ G+
Sbjct: 454 DGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLS 513
Query: 486 CEQPRCDPADDD--GGLD--CDRAPG 507
+ C P D D G LD CD G
Sbjct: 514 HDLLGCRPCDCDVGGALDPQCDEGTG 539
Score = 79.7 bits (195), Expect = 6e-15
Identities = 73/281 (25%), Positives = 102/281 (36%), Gaps = 75/281 (26%)
Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFR--TRSWRAGSYLPLP----HGS 340
C CN HA+ C+ G+ C +T G C +C F R G P P GS
Sbjct: 877 CVCNGHADECNTHTGAC-LGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGS 935
Query: 341 PNACATA----------------------------GSFGN----------CECYGHSNRC 362
AT+ G FG+ CEC G+ +
Sbjct: 936 QRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPM 995
Query: 363 SYIDFLNVVT--CVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDR 420
D + T C+ C H+T G HC HC+ G++ + + C C CN +G+ +
Sbjct: 996 DP-DACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQ-----SCHRCTCNLLGTNPQQ 1049
Query: 421 C---------NETGFCECREGAAGPKCDDCLPTHYWR----QGCYPNVCDDDQLLCQNGG 467
C +G C C GP CD C P ++W GC P C + G
Sbjct: 1050 CPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAP-NFWNLTSGHGCQPCACHPSR---ARGP 1105
Query: 468 TCLQ-NQRCACPRGYTGVRCEQPR----CDPADDDGGLDCD 503
TC + +C C G+ G C + + DP DCD
Sbjct: 1106 TCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCD 1146
Score = 79.7 bits (195), Expect = 6e-15
Identities = 62/229 (27%), Positives = 84/229 (36%), Gaps = 40/229 (17%)
Query: 285 GRCK-CNLHANLCSMREGSL-----QC-ECEHNTTGPDCGKCKKNFRTRSWRAGSY---L 334
GRC+ C N+ M + QC C H+T GP C CK F ++ R +
Sbjct: 981 GRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTC 1040
Query: 335 PLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYR 394
L +P C + C C S +C C N +G C C ++
Sbjct: 1041 NLLGTNPQQCPSPDQ---CHCDPSSGQCP------------CLPNVQGPSCDRCAPNFWN 1085
Query: 395 NGSAELDDENVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYP 453
L + C C C+ + CNE TG C CR G G C +C H+ G
Sbjct: 1086 -----LTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQC 1140
Query: 454 NVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQ---------PRCDP 493
+ CD D C+C G +GVRC+Q P C P
Sbjct: 1141 HACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHP 1189
Score = 63.2 bits (152), Expect = 6e-10
Identities = 56/186 (30%), Positives = 68/186 (36%), Gaps = 38/186 (20%)
Query: 341 PNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAEL 400
P C GS + EC H +C CK G+ C C GYY G
Sbjct: 782 PCQCNPQGSLSS-ECNPHGGQCL------------CKPGVVGRRCDLCAPGYYGFGPTG- 827
Query: 401 DDENVCIECNCNQIGSVHDRCNET-GFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDD 459
C C C+ G++ C +T G C CR GA G +CD C + C P VC+
Sbjct: 828 -----CQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGH 882
Query: 460 QLLCQ-NGGTCLQNQRCACPRGYTGVRCEQPRC------DPADDDGG----LDCDRAPGA 508
C + G CL C G CE RC DP GG C PG+
Sbjct: 883 ADECNTHTGACL-----GCRDHTGGEHCE--RCIAGFHGDPRLPYGGQCRPCPCPEGPGS 935
Query: 509 APRPAT 514
AT
Sbjct: 936 QRHFAT 941
Score = 55.5 bits (132), Expect = 1e-07
Identities = 40/130 (30%), Positives = 54/130 (41%), Gaps = 26/130 (20%)
Query: 404 NVCIECNCNQIGSVHDRCN-ETGFCECREGAAGPKCDDCLPTHY--WRQGCYPNVCDDD- 459
N + C CN GS+ CN G C C+ G G +CD C P +Y GC C +
Sbjct: 778 NGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEG 837
Query: 460 --QLLCQNGGTCLQNQRCACPRGYTGVRCEQ--------PRCDPADDDGGLD-CDRAPGA 508
LC+ + +C C G G+RC++ P C P +G D C+ GA
Sbjct: 838 ALSSLCEK-----TSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGA 892
Query: 509 APRPATLLGC 518
LGC
Sbjct: 893 C------LGC 896
Score = 50.1 bits (118), Expect = 5e-06
Identities = 37/144 (25%), Positives = 57/144 (39%), Gaps = 21/144 (14%)
Query: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCS 363
QC C+ + G C +C+ F S L NA T G+ C +S C
Sbjct: 437 QCRCKEHVVGTRCQQCRDGFFGLS--ISDRLGCRRCQCNARGTVP--GSTPCDPNSGSCY 492
Query: 364 YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE 423
CK G+ C C G++ L C C+C+ G++ +C+E
Sbjct: 493 ------------CKRLVTGRGCDRCLPGHWGLSHDLLG----CRPCDCDVGGALDPQCDE 536
Query: 424 -TGFCECREGAAGPKCDDCLPTHY 446
TG C CR+ G +C+ P ++
Sbjct: 537 GTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 32.3 bits (72), Expect = 1.1
Identities = 30/127 (23%), Positives = 49/127 (38%), Gaps = 28/127 (22%)
Query: 275 FYAISNIEVIG--RCKCNLHANL-----CSMREGSLQCECEHNTTGPDCGKCKKNFRTRS 327
F+ +S + +G RC+CN + C GS C C+ TG C +C
Sbjct: 456 FFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGS--CYCKRLVTGRGCDRCLPGH---- 509
Query: 328 WRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQH 387
W G L P C G+ + +C + +C C+ + G+ C+
Sbjct: 510 W--GLSHDLLGCRPCDCDVGGAL-DPQCDEGTGQCH------------CRQHMVGRRCEQ 554
Query: 388 CRLGYYR 394
+ GY+R
Sbjct: 555 VQPGYFR 561
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 152 bits (383), Expect = 1e-36
Identities = 122/464 (26%), Positives = 196/464 (42%), Gaps = 72/464 (15%)
Query: 60 TCG-DPPERFCSHENPY-LCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPS 117
TCG PE +C+ + + +CD+ P + R+ G +WQS +
Sbjct: 46 TCGLTKPETYCTQYGEWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQS---QNDVN 102
Query: 118 PLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGM 177
P+ + L ++ +V+M F+ P M++E+S D G+TW+ YQ+ A DC F
Sbjct: 103 PVSLQLDLDRRFQLQ---EVMMEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFP- 158
Query: 178 SARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRL 237
R R S V C R + G N+ +L + +
Sbjct: 159 ---RVRQGRPQSWQDVRCQS---------------LPQRPNARLNGGKVQLNLMDLVSGI 200
Query: 238 ESAKGLK--EFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANL 295
+ + K E +T+LR+ R L + + +YA+S + + G C C+ HA+
Sbjct: 201 PATQSQKIQEVGEITNLRVNFTR--LAPVPQRGYHPPSAYYAVSQLRLQGSCFCHGHADR 258
Query: 296 CSMREGSLQ-----------CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 344
C+ + G+ C C+HNT GP+C +C + R WR P
Sbjct: 259 CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWR-----------PAEG 307
Query: 345 ATAGSFGNCECYGHSNRCSYIDFLNVVT-------CVSCKHNTRGQHCQHCRLGYYRNGS 397
A C+C GHS C + + + C +C+ +T G++C+ C+L Y+RN
Sbjct: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRR 367
Query: 398 AELDDENVCIECNCNQIGSVHDR-CNE-TGFCECREGAAGPKCDDCLP-----THYWRQG 450
+ CI C C+ G+V C+ TG C C+E G +CD C P T+ QG
Sbjct: 368 PGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQG 427
Query: 451 CYPNVCDDDQLLCQNGGTC-LQNQRCACPRGYTGVRCEQPRCDP 493
C+ CD + L + C ++ RC C G +C+Q C P
Sbjct: 428 CHR--CDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQ--CAP 467
Score = 47.8 bits (112), Expect = 3e-05
Identities = 42/164 (25%), Positives = 60/164 (36%), Gaps = 34/164 (20%)
Query: 286 RCKCNLHANLCSMR--EGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNA 343
RC CN+ + M E S +C C N GP C +C W+ S P A
Sbjct: 430 RCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYH----WKLASGQGC---EPCA 482
Query: 344 CATAGSFGNCECYGHSNRCSYIDFLNVVTCVS-----CKHNTRGQHCQHCRLGYYRNGSA 398
C S +C + +C + + C + C T G CR
Sbjct: 483 CDPHNSLSP-QCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRA-------- 533
Query: 399 ELDDENVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDC 441
C+C+ G+ C++ +G C CR G GP+CD C
Sbjct: 534 ----------CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQC 567
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 152 bits (383), Expect = 1e-36
Identities = 122/464 (26%), Positives = 196/464 (42%), Gaps = 72/464 (15%)
Query: 60 TCG-DPPERFCSHENPY-LCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPS 117
TCG PE +C+ + + +CD+ P + R+ G +WQS +
Sbjct: 46 TCGLTKPETYCTQYGEWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQS---QNDVN 102
Query: 118 PLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGM 177
P+ + L ++ +V+M F+ P M++E+S D G+TW+ YQ+ A DC F
Sbjct: 103 PVSLQLDLDRRFQLQ---EVMMEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFP- 158
Query: 178 SARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRL 237
R R S V C R + G N+ +L + +
Sbjct: 159 ---RVRQGRPQSWQDVRCQS---------------LPQRPNARLNGGKVQLNLMDLVSGI 200
Query: 238 ESAKGLK--EFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANL 295
+ + K E +T+LR+ R L + + +YA+S + + G C C+ HA+
Sbjct: 201 PATQSQKIQEVGEITNLRVNFTR--LAPVPQRGYHPPSAYYAVSQLRLQGSCFCHGHADR 258
Query: 296 CSMREGSLQ-----------CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 344
C+ + G+ C C+HNT GP+C +C + R WR P
Sbjct: 259 CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWR-----------PAEG 307
Query: 345 ATAGSFGNCECYGHSNRCSYIDFLNVVT-------CVSCKHNTRGQHCQHCRLGYYRNGS 397
A C+C GHS C + + + C +C+ +T G++C+ C+L Y+RN
Sbjct: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRR 367
Query: 398 AELDDENVCIECNCNQIGSVHDR-CNE-TGFCECREGAAGPKCDDCLP-----THYWRQG 450
+ CI C C+ G+V C+ TG C C+E G +CD C P T+ QG
Sbjct: 368 PGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQG 427
Query: 451 CYPNVCDDDQLLCQNGGTC-LQNQRCACPRGYTGVRCEQPRCDP 493
C+ CD + L + C ++ RC C G +C+Q C P
Sbjct: 428 CHR--CDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQ--CAP 467
Score = 47.8 bits (112), Expect = 3e-05
Identities = 42/164 (25%), Positives = 60/164 (36%), Gaps = 34/164 (20%)
Query: 286 RCKCNLHANLCSMR--EGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNA 343
RC CN+ + M E S +C C N GP C +C W+ S P A
Sbjct: 430 RCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYH----WKLASGQGC---EPCA 482
Query: 344 CATAGSFGNCECYGHSNRCSYIDFLNVVTCVS-----CKHNTRGQHCQHCRLGYYRNGSA 398
C S +C + +C + + C + C T G CR
Sbjct: 483 CDPHNSLSP-QCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRA-------- 533
Query: 399 ELDDENVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDC 441
C+C+ G+ C++ +G C CR G GP+CD C
Sbjct: 534 ----------CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQC 567
>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 152 bits (383), Expect = 1e-36
Identities = 122/464 (26%), Positives = 196/464 (42%), Gaps = 72/464 (15%)
Query: 60 TCG-DPPERFCSHENPY-LCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPS 117
TCG PE +C+ + + +CD+ P + R+ G +WQS +
Sbjct: 46 TCGLTKPETYCTQYGEWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQS---QNDVN 102
Query: 118 PLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGM 177
P+ + L ++ +V+M F+ P M++E+S D G+TW+ YQ+ A DC F
Sbjct: 103 PVSLQLDLDRRFQLQ---EVMMEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFP- 158
Query: 178 SARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRL 237
R R S V C R + G N+ +L + +
Sbjct: 159 ---RVRQGRPQSWQDVRCQS---------------LPQRPNARLNGGKVQLNLMDLVSGI 200
Query: 238 ESAKGLK--EFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANL 295
+ + K E +T+LR+ R L + + +YA+S + + G C C+ HA+
Sbjct: 201 PATQSQKIQEVGEITNLRVNFTR--LAPVPQRGYHPPSAYYAVSQLRLQGSCFCHGHADR 258
Query: 296 CSMREGSLQ-----------CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 344
C+ + G+ C C+HNT GP+C +C + R WR P
Sbjct: 259 CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWR-----------PAEG 307
Query: 345 ATAGSFGNCECYGHSNRCSYIDFLNVVT-------CVSCKHNTRGQHCQHCRLGYYRNGS 397
A C+C GHS C + + + C +C+ +T G++C+ C+L Y+RN
Sbjct: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRR 367
Query: 398 AELDDENVCIECNCNQIGSVHDR-CNE-TGFCECREGAAGPKCDDCLP-----THYWRQG 450
+ CI C C+ G+V C+ TG C C+E G +CD C P T+ QG
Sbjct: 368 PGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQG 427
Query: 451 CYPNVCDDDQLLCQNGGTC-LQNQRCACPRGYTGVRCEQPRCDP 493
C+ CD + L + C ++ RC C G +C+Q C P
Sbjct: 428 CHR--CDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQ--CAP 467
Score = 47.8 bits (112), Expect = 3e-05
Identities = 42/164 (25%), Positives = 60/164 (36%), Gaps = 34/164 (20%)
Query: 286 RCKCNLHANLCSMR--EGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNA 343
RC CN+ + M E S +C C N GP C +C W+ S P A
Sbjct: 430 RCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYH----WKLASGQGC---EPCA 482
Query: 344 CATAGSFGNCECYGHSNRCSYIDFLNVVTCVS-----CKHNTRGQHCQHCRLGYYRNGSA 398
C S +C + +C + + C + C T G CR
Sbjct: 483 CDPHNSLSP-QCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRA-------- 533
Query: 399 ELDDENVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDC 441
C+C+ G+ C++ +G C CR G GP+CD C
Sbjct: 534 ----------CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQC 567
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 147 bits (370), Expect = 3e-35
Identities = 131/487 (26%), Positives = 197/487 (40%), Gaps = 84/487 (17%)
Query: 60 TCGDP-PERFCSH---------ENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQS 109
TCG+ PE FC NP + +++NP HP D G +WQS
Sbjct: 40 TCGEKGPEMFCKLVEHVPGRPVRNPQCRICDGNSANPRERHPISHAID----GTNNWWQS 95
Query: 110 ITWSRYPSPLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYA- 168
+ ITL + ++ ++ RP +LE+SLD G T+ P+Q+YA
Sbjct: 96 PSIQNGREYHWVTITLDLRQVFQVAYVIIKAANAPRPGNWILERSLD-GTTFSPWQYYAV 154
Query: 169 --EDCMEAFGMSARRARDMSSSSAHRVLCTEEYSRWAGSKK-EKHVRFEVRDRFAIFAGP 225
+C+ + ++ RR + + V+CT YSR + E H A P
Sbjct: 155 SDSECLSRYNITPRRG-PPTYRADDEVICTSYYSRLVPLEHGEIHTSLINGRPSADDLSP 213
Query: 226 DLRNMDN---LYTRLESAKGLK-EFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNI 281
L + + RL+ + L + TL+ + L P + +Y+Y+I +I
Sbjct: 214 KLLEFTSARYIRLRLQRIRTLNADLMTLSHREPKELDPIV---------TRRYYYSIKDI 264
Query: 282 EVIGRCKCNLHANLCSMREGS--LQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHG 339
V G C C HA+ C E + LQC+CEHNT G C +C + + WR G+
Sbjct: 265 SVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTV-----S 319
Query: 340 SPNACATAGSFGNCECYGHSNRCSYID--------------FLNVVTCVSCKHNTRGQHC 385
S N C C C+ + C Y + F C++C NT G +C
Sbjct: 320 SGNTCEA------CNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINC 373
Query: 386 QHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRC------------NETGFCECREGA 433
+ C GYYR ++ C CNC+ +GS+ C + G C C+EG
Sbjct: 374 ETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGY 433
Query: 434 AGPKCDDC------LPTHYWRQGCYPNVCDDDQLLCQNGGTCLQN---QRC-ACPRGYTG 483
G KCD C PT GC P D+ C C +N + C C G+
Sbjct: 434 TGEKCDRCQLGYKDYPTCV-SCGCNPVGSASDE-PCTGPCVCKENVEGKACDRCKPGFYN 491
Query: 484 VRCEQPR 490
++ + PR
Sbjct: 492 LKEKNPR 498
Score = 90.1 bits (222), Expect = 4e-18
Identities = 70/239 (29%), Positives = 92/239 (38%), Gaps = 25/239 (10%)
Query: 286 RCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCK----KNFRTRSWRAGSYLP-LPHGS 340
RC + N E + C+C N + G C + + G++ G
Sbjct: 830 RCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGF 889
Query: 341 PNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAEL 400
TA + CEC+ + S + L C CK N GQ C C GYY L
Sbjct: 890 YGDAVTAKNCRACECHVKGSH-SAVCHLETGLC-DCKPNVTGQQCDQCLHGYYG-----L 942
Query: 401 DDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQ--GCYPNVCDD 458
D + C CNC+ GSV D C + G C C G AG +CD C Y Q C P C
Sbjct: 943 DSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPH 1002
Query: 459 DQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDPADDDGGLDCDRAPGAAPRPATLLG 517
Q C + C CP GV+CE+ C +DG D G +L+G
Sbjct: 1003 TQNTCDP-----ETGECVCPPHTQGVKCEE--C----EDGHWGYDAEVGCQACNCSLVG 1050
Score = 83.2 bits (204), Expect = 5e-16
Identities = 57/179 (31%), Positives = 73/179 (40%), Gaps = 28/179 (15%)
Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPL---PHGSPNA 343
C CN H++ C G C NT G C C + + + S L PH P
Sbjct: 1403 CSCNNHSDTCDPNTGKC-LNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPP-- 1459
Query: 344 CATAGSFGNCECYG-HSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDD 402
A C G H RC +C G+HC+ C YY N
Sbjct: 1460 ---ASFSPTCVLEGDHDFRCD-----------ACLLGYEGKHCERCSSSYYGNPQTP--- 1502
Query: 403 ENVCIECNCNQIGSVHDRCNET-GFCECREGAAGPKCDDCLPTHYWRQ-GCYPNVCDDD 459
C +C+CN GSVH C+ T G C CR GA+G +CD+C P H + C CDD+
Sbjct: 1503 GGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRHILMETDCVS--CDDE 1559
Score = 76.6 bits (187), Expect = 5e-14
Identities = 57/227 (25%), Positives = 87/227 (38%), Gaps = 43/227 (18%)
Query: 275 FYAISNIEVIGRCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYL 334
+Y + + C C++ ++ QC C G C +C F +++ GS
Sbjct: 939 YYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGF--YAYQDGSCT 996
Query: 335 PLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYR 394
P C+C N C CV C +T+G C+ C G++
Sbjct: 997 P-----------------CDCPHTQNTCD----PETGECV-CPPHTQGVKCEECEDGHW- 1033
Query: 395 NGSAELDDENVCIECNCNQIGSVHDRCN-ETGFCECREGAAGPKCD----------DCLP 443
D E C CNC+ +GS H RC+ TG C+C+ G CD DC+P
Sbjct: 1034 ----GYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDCVP 1089
Query: 444 THYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPR 490
+G + C+ +Q LC G + C C G +C + R
Sbjct: 1090 CDCDLRGTSGDACNLEQGLC---GCVEETGACPCKENVFGPQCNECR 1133
Score = 62.4 bits (150), Expect = 1e-09
Identities = 51/203 (25%), Positives = 71/203 (34%), Gaps = 46/203 (22%)
Query: 305 CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSY 364
CEC TG C C + +R L G CEC+GH+ C+
Sbjct: 709 CECPQGYTGTSCESCLSGY----YRVDGIL-----------FGGICQPCECHGHAAECNV 753
Query: 365 IDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC-------NQIGSV 417
C++C HNT G HC+ C G+Y G C C C N +
Sbjct: 754 HG-----VCIACAHNTTGVHCEQCLPGFY--GEPSRGTPGDCQPCACPLTIASNNFSPTC 806
Query: 418 HDRCNETGFCE-CREGAAGPKCDDCLPTHYWR-----QGCYPNVCDDDQLLCQNG----- 466
H + C+ C G +G C+ C +Y + C P C + + G
Sbjct: 807 HLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSV 866
Query: 467 -GTCLQNQRCACPRGYTGVRCEQ 488
G CL+ C G CE+
Sbjct: 867 TGECLK-----CLGNTDGAHCER 884
Score = 62.0 bits (149), Expect = 1e-09
Identities = 47/161 (29%), Positives = 60/161 (37%), Gaps = 15/161 (9%)
Query: 299 REGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGH 358
R G + C NT G +C C + R + Y P P C GS + C
Sbjct: 356 RGGGVCINCLQNTMGINCETCIDGYY-RPHKVSPYEDEPC-RPCNCDPVGSLSSV-CIKD 412
Query: 359 SNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVH 418
+ C CK G+ C C+LGY D C+ C CN +GS
Sbjct: 413 DLHSDLHNGKQPGQC-PCKEGYTGEKCDRCQLGY--------KDYPTCVSCGCNPVGSAS 463
Query: 419 DR-CNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDD 458
D C TG C C+E G CD C P Y + P C +
Sbjct: 464 DEPC--TGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSE 502
Score = 39.7 bits (91), Expect = 0.007
Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 16/78 (20%)
Query: 289 CNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAG 348
CNL LC E + C C+ N GP C +C R G++ L +P C+
Sbjct: 1102 CNLEQGLCGCVEETGACPCKENVFGPQCNEC---------REGTF-ALRADNPLGCSP-- 1149
Query: 349 SFGNCECYGHSNRCSYID 366
C C G S+ CS ++
Sbjct: 1150 ----CFCSGLSHLCSELE 1163
Score = 29.3 bits (64), Expect = 9.3
Identities = 9/15 (60%), Positives = 11/15 (73%)
Query: 473 QRCACPRGYTGVRCE 487
+ C CP+GYTG CE
Sbjct: 707 EHCECPQGYTGTSCE 721
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 142 bits (359), Expect = 6e-34
Identities = 132/502 (26%), Positives = 206/502 (41%), Gaps = 91/502 (18%)
Query: 60 TCG-DPPERFC--SH----ENPYLCSNEC---DASNPDLAHPPRLMFDKEEEGLATYWQS 109
TCG PE +C SH + ++C+++ + NPD ++ L +WQS
Sbjct: 55 TCGLHKPEPYCIVSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQS 114
Query: 110 ITWSRYPSPLEANITLSWNKTVELT-DDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYA 168
N+T+ + E ++MTF+ RP M++E+S D G+TW Y+++A
Sbjct: 115 ENGVE-------NVTIQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDFGKTWGVYRYFA 167
Query: 169 EDCMEAF-GMSARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDL 227
DC +F G+S + + ++C YS S E V F D P
Sbjct: 168 YDCEASFPGISTGPMKKVDD-----IICDSRYSDIEPST-EGEVIFRALD-------PAF 214
Query: 228 RNMDNLYTRLESAKGLKEFFTLTDLRMRLLR-PALGGTYV--QRENLYKYFYAISNIEVI 284
+ D R+++ +T+LR++ ++ LG + + E KY+YA+ ++ V
Sbjct: 215 KIEDPYSPRIQN------LLKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMVVR 268
Query: 285 GRCKCNLHANLCSMREGSLQ---------CECEHNTTGPDCGKCKKNFRTRSWRAGSYLP 335
G C C HA+ C+ +G + C C HNT G +C C + WR P
Sbjct: 269 GNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWR-----P 323
Query: 336 LPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVT-------CVSCKHNTRGQHCQHC 388
+ NAC C C HS C + + + T C C+HNT G++C+ C
Sbjct: 324 AEGRNSNACK------KCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQC 377
Query: 389 RLGYYRNGSAELDDENVCIECNCNQIGSVHDR-CNE---------TGFCECREGAAGPKC 438
+ YY++ ++ D N C C C+ GS ++ C+ G C C+ G C
Sbjct: 378 KPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHC 437
Query: 439 DDCLPTHYWRQ-----GCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDP 493
D C Y GC C+ + + C C R TG C+Q C P
Sbjct: 438 DVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQ--CLP 495
Query: 494 A------DDDGGLDCDRAPGAA 509
D DG CD G A
Sbjct: 496 EHWGLSNDLDGCRPCDCDLGGA 517
Score = 79.3 bits (194), Expect = 8e-15
Identities = 62/220 (28%), Positives = 90/220 (40%), Gaps = 45/220 (20%)
Query: 303 LQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRC 362
L C C+ G C C + G+P+ GS C+C+ + +
Sbjct: 942 LACVCDPGYIGSRCDDCASGY--------------FGNPSE--VGGSCQPCQCHNNIDTT 985
Query: 363 SYIDFLNVVT--CVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDR 420
+ + T C+ C ++T G+HCQ CR GYY G A D C +C CN +G+V +
Sbjct: 986 DP-EACDKETGRCLKCLYHTEGEHCQFCRFGYY--GDALQQD---CRKCVCNYLGTVQEH 1039
Query: 421 CN--------ETGFCECREGAAGPKCDDCLPTHYWR----QGCYPNVCDDDQLLCQNGGT 468
CN TG C C G CD C P + W+ GC P C+ G +
Sbjct: 1040 CNGSDCQCDKATGQCLCLPNVIGQNCDRCAP-NTWQLASGTGCDPCNCNAAHSF---GPS 1095
Query: 469 CLQ-NQRCACPRGYTGVRCEQPR----CDPADDDGGLDCD 503
C + +C C G+ G C + + DP + DCD
Sbjct: 1096 CNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCD 1135
Score = 60.5 bits (145), Expect = 4e-09
Identities = 50/162 (30%), Positives = 62/162 (38%), Gaps = 24/162 (14%)
Query: 353 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412
CEC + S D N C C+ N G+ C C G + G + C C C+
Sbjct: 773 CECDPQGSLSSVCD-PNGGQC-QCRPNVVGRTCNRCAPGTFGFGPSG------CKPCECH 824
Query: 413 QIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQN-GGTCL 470
GSV+ CN TG C C +G +CD CLP H+ C P C+ C G CL
Sbjct: 825 LQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGECL 884
Query: 471 QNQ------RC-ACPRGY-------TGVRCEQPRCDPADDDG 498
Q C C GY +G C C D G
Sbjct: 885 NCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSG 926
Score = 58.5 bits (140), Expect = 1e-08
Identities = 45/165 (27%), Positives = 65/165 (39%), Gaps = 35/165 (21%)
Query: 286 RCKCNL------HANL--CSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLP 337
+C CN H N C + + QC C N G +C +C N +W+ S
Sbjct: 1027 KCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPN----TWQLASGTGC- 1081
Query: 338 HGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGS 397
P C A SFG C + +C C G+ C C+ ++ +
Sbjct: 1082 --DPCNCNAAHSFGP-SCNEFTGQCQ------------CMPGFGGRTCSECQELFWGDPD 1126
Query: 398 AELDDENVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDC 441
E C C+C+ G +C++ TG C C EG GP+CD C
Sbjct: 1127 VE------CRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKC 1165
Score = 56.6 bits (135), Expect = 5e-08
Identities = 59/259 (22%), Positives = 88/259 (33%), Gaps = 65/259 (25%)
Query: 287 CKCNLHANLCSMRE-GSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLP---HGSPN 342
C+C+ +L S+ + QC+C N G C +C T + P GS N
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPG--TFGFGPSGCKPCECHLQGSVN 830
Query: 343 ACAT---------------------AGSFG-----NCECYGHSNRCSYIDFLNVVTCVSC 376
A G +G C+C GH++ C + C++C
Sbjct: 831 AFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPV----TGECLNC 886
Query: 377 KHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQ---------IGSVHDRCNETGFC 427
+ T G +C+ C GYY G + + C C C D C
Sbjct: 887 QDYTMGHNCERCLAGYY--GDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLAC 944
Query: 428 ECREGAAGPKCDDCLPTHYWRQG----------CYPNVCDDDQLLC-QNGGTCL------ 470
C G G +CDDC ++ C+ N+ D C + G CL
Sbjct: 945 VCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHT 1004
Query: 471 QNQRCA-CPRGYTGVRCEQ 488
+ + C C GY G +Q
Sbjct: 1005 EGEHCQFCRFGYYGDALQQ 1023
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 134 bits (338), Expect = 2e-31
Identities = 127/491 (25%), Positives = 194/491 (39%), Gaps = 78/491 (15%)
Query: 60 TCGDP-PERFCSH---------ENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQS 109
TCG+ PE +C NP ++SNP+ HP D G T+WQS
Sbjct: 57 TCGEKGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAID----GKNTWWQS 112
Query: 110 ITWSRYPSPLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYA- 168
+ ITL + ++ +V RP +LE+SLD+ ++P+Q++A
Sbjct: 113 PSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVE-YKPWQYHAV 171
Query: 169 --EDCMEAFGMSARRARDMSSSSAHRVLCTEEYSRWAGSKK-EKHVRFEVRDRFAIFAGP 225
+C+ + + R S + V+CT YS+ + E H+ A P
Sbjct: 172 TDTECLTLYNIYPRTGPP-SYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSP 230
Query: 226 DLRNMDNL-YTRLESAKGLKEFFTLT-DLRMRLLR-PALGGTYVQRENLYKYFYAISNIE 282
+L + Y RL + TL DL M + P V R +Y+Y++ +I
Sbjct: 231 ELLEFTSARYIRLR----FQRIRTLNADLMMFAHKDPREIDPIVTR----RYYYSVKDIS 282
Query: 283 VIGRCKCNLHANLCSMREGS--LQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGS 340
V G C C HA C + + +CECEHNT G C +C F + WRAG++L
Sbjct: 283 VGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFL------ 336
Query: 341 PNACATAGSFGNCECYGHSNRCSYID--------------FLNVVTCVSCKHNTRGQHCQ 386
T C C+G + C Y + ++ C++C NT G +C+
Sbjct: 337 -----TKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCE 391
Query: 387 HCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE----------TGFCECREGAAGP 436
C G++R + C C+C+ IGS+++ C + G C C+ G G
Sbjct: 392 TCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGV 451
Query: 437 KCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDPA-- 494
CD C + C C+ L +N C C C G C RC
Sbjct: 452 SCDRCARGYTGYPDC--KACNCSGLGSKNEDPCF--GPCICKENVEGGDCS--RCKSGFF 505
Query: 495 --DDDGGLDCD 503
+D CD
Sbjct: 506 NLQEDNWKGCD 516
Score = 88.6 bits (218), Expect = 1e-17
Identities = 60/177 (33%), Positives = 79/177 (44%), Gaps = 23/177 (12%)
Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346
C+CN H++LC E S+ C+H+T G C +C A Y + G PN C
Sbjct: 1420 CQCNGHSSLCDP-ETSICQNCQHHTAGDFCERC----------ALGYYGIVKGLPNDCQQ 1468
Query: 347 AGSFGNCECYGHSNRCS---YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDE 403
C SN S + L+ C +C GQ+C+ C GY GS +
Sbjct: 1469 CA----CPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGY--TGSPG-NPG 1521
Query: 404 NVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDD 459
C EC C+ GS+ C+ TGFC CR GA G KCD C H R+G C D+
Sbjct: 1522 GSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKHWHA-REGWECVFCGDE 1577
Score = 84.0 bits (206), Expect = 3e-16
Identities = 60/213 (28%), Positives = 83/213 (38%), Gaps = 37/213 (17%)
Query: 287 CKCNLHANL-----CSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSP 341
C+CN + + C GS C+ TTG C C + G + + P
Sbjct: 865 CQCNDNLDFSIPGSCDSLSGSCLI-CKPGTTGRYCELCADGY------FGDAVDAKNCQP 917
Query: 342 NACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELD 401
C GSF C+ + +C C+ N +GQ C C+ G + SA
Sbjct: 918 CRCNAGGSFSEV-CHSQTGQCE------------CRANVQGQRCDKCKAGTFGLQSAR-- 962
Query: 402 DENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQL 461
C+ CNCN GS C E+G C C+ G G KCD C ++ Q C+ L
Sbjct: 963 ---GCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHL 1019
Query: 462 LCQNGGTC-LQNQRCACPRGYTGVRCEQPRCDP 493
G C + RC CP G +C +C P
Sbjct: 1020 ----GNNCDPKTGRCICPPNTIGEKCS--KCAP 1046
Score = 61.6 bits (148), Expect = 2e-09
Identities = 57/243 (23%), Positives = 86/243 (35%), Gaps = 56/243 (23%)
Query: 290 NLHANLCSMREGSLQ-----CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 344
NL + + +GS+ C+C TG C C W H N
Sbjct: 704 NLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESC--------WPR-------HRRVNGT 748
Query: 345 ATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDEN 404
G C+C+GH+ C + C++CK +T G +C C G+Y G
Sbjct: 749 IFGGICEPCQCFGHAESCDDV----TGECLNCKDHTGGPYCDKCLPGFY--GEPTKGTSE 802
Query: 405 VCIECNC-------NQIGSVHDRCNETGFCE-CREGAAGPKCDDCLPTHYWRQ-----GC 451
C C C N + H + C+ C G GP+C+ C ++ + C
Sbjct: 803 DCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSC 862
Query: 452 YPNVCDDDQ---------------LLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDPADD 496
P C+D+ L+C+ G T + CA GY G + C P
Sbjct: 863 QPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCA--DGYFGDAVDAKNCQPCRC 920
Query: 497 DGG 499
+ G
Sbjct: 921 NAG 923
Score = 53.5 bits (127), Expect = 5e-07
Identities = 44/136 (32%), Positives = 54/136 (39%), Gaps = 24/136 (17%)
Query: 376 CKHNTRGQHCQHCRLGYYR-----NGSAELDDENVCIECNCNQIGSVHDRCNETGFCE-C 429
C G C+ C G+YR G C+ C CN S+ D ET C+ C
Sbjct: 1382 CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDP--ETSICQNC 1439
Query: 430 REGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLC-------QNGGTC----LQNQRC-AC 477
+ AG C+ C +Y PN C Q C +C L + RC AC
Sbjct: 1440 QHHTAGDFCERCALGYYGIVKGLPNDCQ--QCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497
Query: 478 PRGYTGVRCEQPRCDP 493
PRGY G CE RC P
Sbjct: 1498 PRGYEGQYCE--RCAP 1511
Score = 51.6 bits (122), Expect = 2e-06
Identities = 45/186 (24%), Positives = 66/186 (35%), Gaps = 26/186 (13%)
Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346
C+C+ N C + G +C C NT G C KC N S G C+T
Sbjct: 1014 CECSHLGNNCDPKTG--RCICPPNTIGEKCSKCAPNTWGHSITTGC-------KACNCST 1064
Query: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKH-NTRGQHCQHCRLGYYRNGSAELDDENV 405
GS + +C ++ +C+ + C C + C C + D E
Sbjct: 1065 VGSL-DFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETK 1123
Query: 406 CIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQN 465
+C+C+ ++TG C C+ G CD C P + P C C
Sbjct: 1124 --KCSCS---------DQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSS----CYC 1168
Query: 466 GGTCLQ 471
GT Q
Sbjct: 1169 FGTTTQ 1174
Score = 33.5 bits (75), Expect = 0.49
Identities = 20/75 (26%), Positives = 32/75 (42%), Gaps = 16/75 (21%)
Query: 289 CNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAG 348
C+ CS + + QC C+ N G C +C R G + L +P C+
Sbjct: 1118 CDSETKKCSCSDQTGQCTCKVNVEGIHCDRC---------RPGKF-GLDAKNPLGCS--- 1164
Query: 349 SFGNCECYGHSNRCS 363
+C C+G + +CS
Sbjct: 1165 ---SCYCFGTTTQCS 1176
Score = 32.0 bits (71), Expect = 1.4
Identities = 24/92 (26%), Positives = 34/92 (36%), Gaps = 27/92 (29%)
Query: 427 CECREGAAGPKCDDCLPTHYWRQG-------------CYP-------NVCDDDQLLCQNG 466
C+C G +G C+ CLP Y + C P ++CD + +CQN
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNC 1439
Query: 467 GTCLQNQRC-ACPRGYTGV------RCEQPRC 491
C C GY G+ C+Q C
Sbjct: 1440 QHHTAGDFCERCALGYYGIVKGLPNDCQQCAC 1471
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 134 bits (338), Expect = 2e-31
Identities = 127/491 (25%), Positives = 194/491 (39%), Gaps = 78/491 (15%)
Query: 60 TCGDP-PERFCSH---------ENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQS 109
TCG+ PE +C NP ++SNP+ HP D G T+WQS
Sbjct: 57 TCGEKGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAID----GKNTWWQS 112
Query: 110 ITWSRYPSPLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYA- 168
+ ITL + ++ +V RP +LE+SLD+ ++P+Q++A
Sbjct: 113 PSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVE-YKPWQYHAV 171
Query: 169 --EDCMEAFGMSARRARDMSSSSAHRVLCTEEYSRWAGSKK-EKHVRFEVRDRFAIFAGP 225
+C+ + + R S + V+CT YS+ + E H+ A P
Sbjct: 172 TDTECLTLYNIYPRTGPP-SYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSP 230
Query: 226 DLRNMDNL-YTRLESAKGLKEFFTLT-DLRMRLLR-PALGGTYVQRENLYKYFYAISNIE 282
+L + Y RL + TL DL M + P V R +Y+Y++ +I
Sbjct: 231 ELLEFTSARYIRLR----FQRIRTLNADLMMFAHKDPREIDPIVTR----RYYYSVKDIS 282
Query: 283 VIGRCKCNLHANLCSMREGS--LQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGS 340
V G C C HA C + + +CECEHNT G C +C F + WRAG++L
Sbjct: 283 VGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFL------ 336
Query: 341 PNACATAGSFGNCECYGHSNRCSYID--------------FLNVVTCVSCKHNTRGQHCQ 386
T C C+G + C Y + ++ C++C NT G +C+
Sbjct: 337 -----TKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCE 391
Query: 387 HCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE----------TGFCECREGAAGP 436
C G++R + C C+C+ IGS+++ C + G C C+ G G
Sbjct: 392 TCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGV 451
Query: 437 KCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDPA-- 494
CD C + C C+ L +N C C C G C RC
Sbjct: 452 SCDRCARGYTGYPDC--KACNCSGLGSKNEDPCF--GPCICKENVEGGDCS--RCKSGFF 505
Query: 495 --DDDGGLDCD 503
+D CD
Sbjct: 506 NLQEDNWKGCD 516
Score = 88.6 bits (218), Expect = 1e-17
Identities = 60/177 (33%), Positives = 79/177 (44%), Gaps = 23/177 (12%)
Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346
C+CN H++LC E S+ C+H+T G C +C A Y + G PN C
Sbjct: 1420 CQCNGHSSLCDP-ETSICQNCQHHTAGDFCERC----------ALGYYGIVKGLPNDCQQ 1468
Query: 347 AGSFGNCECYGHSNRCS---YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDE 403
C SN S + L+ C +C GQ+C+ C GY GS +
Sbjct: 1469 CA----CPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGY--TGSPG-NPG 1521
Query: 404 NVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDD 459
C EC C+ GS+ C+ TGFC CR GA G KCD C H R+G C D+
Sbjct: 1522 GSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKHWHA-REGWECVFCGDE 1577
Score = 84.0 bits (206), Expect = 3e-16
Identities = 60/213 (28%), Positives = 83/213 (38%), Gaps = 37/213 (17%)
Query: 287 CKCNLHANL-----CSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSP 341
C+CN + + C GS C+ TTG C C + G + + P
Sbjct: 865 CQCNDNLDFSIPGSCDSLSGSCLI-CKPGTTGRYCELCADGY------FGDAVDAKNCQP 917
Query: 342 NACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELD 401
C GSF C+ + +C C+ N +GQ C C+ G + SA
Sbjct: 918 CRCNAGGSFSEV-CHSQTGQCE------------CRANVQGQRCDKCKAGTFGLQSAR-- 962
Query: 402 DENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQL 461
C+ CNCN GS C E+G C C+ G G KCD C ++ Q C+ L
Sbjct: 963 ---GCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHL 1019
Query: 462 LCQNGGTC-LQNQRCACPRGYTGVRCEQPRCDP 493
G C + RC CP G +C +C P
Sbjct: 1020 ----GNNCDPKTGRCICPPNTIGEKCS--KCAP 1046
Score = 61.6 bits (148), Expect = 2e-09
Identities = 57/243 (23%), Positives = 86/243 (35%), Gaps = 56/243 (23%)
Query: 290 NLHANLCSMREGSLQ-----CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 344
NL + + +GS+ C+C TG C C W H N
Sbjct: 704 NLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESC--------WPR-------HRRVNGT 748
Query: 345 ATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDEN 404
G C+C+GH+ C + C++CK +T G +C C G+Y G
Sbjct: 749 IFGGICEPCQCFGHAESCDDV----TGECLNCKDHTGGPYCDKCLPGFY--GEPTKGTSE 802
Query: 405 VCIECNC-------NQIGSVHDRCNETGFCE-CREGAAGPKCDDCLPTHYWRQ-----GC 451
C C C N + H + C+ C G GP+C+ C ++ + C
Sbjct: 803 DCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSC 862
Query: 452 YPNVCDDDQ---------------LLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDPADD 496
P C+D+ L+C+ G T + CA GY G + C P
Sbjct: 863 QPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCA--DGYFGDAVDAKNCQPCRC 920
Query: 497 DGG 499
+ G
Sbjct: 921 NAG 923
Score = 53.5 bits (127), Expect = 5e-07
Identities = 44/136 (32%), Positives = 54/136 (39%), Gaps = 24/136 (17%)
Query: 376 CKHNTRGQHCQHCRLGYYR-----NGSAELDDENVCIECNCNQIGSVHDRCNETGFCE-C 429
C G C+ C G+YR G C+ C CN S+ D ET C+ C
Sbjct: 1382 CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDP--ETSICQNC 1439
Query: 430 REGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLC-------QNGGTC----LQNQRC-AC 477
+ AG C+ C +Y PN C Q C +C L + RC AC
Sbjct: 1440 QHHTAGDFCERCALGYYGIVKGLPNDCQ--QCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497
Query: 478 PRGYTGVRCEQPRCDP 493
PRGY G CE RC P
Sbjct: 1498 PRGYEGQYCE--RCAP 1511
Score = 51.6 bits (122), Expect = 2e-06
Identities = 45/186 (24%), Positives = 66/186 (35%), Gaps = 26/186 (13%)
Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346
C+C+ N C + G +C C NT G C KC N S G C+T
Sbjct: 1014 CECSHLGNNCDPKTG--RCICPPNTIGEKCSKCAPNTWGHSITTGC-------KACNCST 1064
Query: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKH-NTRGQHCQHCRLGYYRNGSAELDDENV 405
GS + +C ++ +C+ + C C + C C + D E
Sbjct: 1065 VGSL-DFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETK 1123
Query: 406 CIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQN 465
+C+C+ ++TG C C+ G CD C P + P C C
Sbjct: 1124 --KCSCS---------DQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSS----CYC 1168
Query: 466 GGTCLQ 471
GT Q
Sbjct: 1169 FGTTTQ 1174
Score = 33.5 bits (75), Expect = 0.49
Identities = 20/75 (26%), Positives = 32/75 (42%), Gaps = 16/75 (21%)
Query: 289 CNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAG 348
C+ CS + + QC C+ N G C +C R G + L +P C+
Sbjct: 1118 CDSETKKCSCSDQTGQCTCKVNVEGIHCDRC---------RPGKF-GLDAKNPLGCS--- 1164
Query: 349 SFGNCECYGHSNRCS 363
+C C+G + +CS
Sbjct: 1165 ---SCYCFGTTTQCS 1176
Score = 32.0 bits (71), Expect = 1.4
Identities = 24/92 (26%), Positives = 34/92 (36%), Gaps = 27/92 (29%)
Query: 427 CECREGAAGPKCDDCLPTHYWRQG-------------CYP-------NVCDDDQLLCQNG 466
C+C G +G C+ CLP Y + C P ++CD + +CQN
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNC 1439
Query: 467 GTCLQNQRC-ACPRGYTGV------RCEQPRC 491
C C GY G+ C+Q C
Sbjct: 1440 QHHTAGDFCERCALGYYGIVKGLPNDCQQCAC 1471
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 126 bits (317), Expect = 4e-29
Identities = 110/454 (24%), Positives = 193/454 (42%), Gaps = 74/454 (16%)
Query: 66 ERFC-SHENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANIT 124
+R+C ++ N NP+ AHP + D + + T W S ++ + L +T
Sbjct: 316 QRYCIPNDAGDTADNRVSRLNPE-AHPLSFVNDND---VGTSWVSNVFTNI-TQLNQGVT 370
Query: 125 LSWNKTVELTDD------VVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMS 178
+S V+L + +++ F +PT + +++ +N W+ +Q++A +C AFGM
Sbjct: 371 IS----VDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNC-GAFGM- 424
Query: 179 ARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLE 238
+ D+ + L ++ ++ +V F + + GP+ R Y
Sbjct: 425 -KNNGDLEKPDSVNCLQLSNFTPYSRG----NVTFSI-----LTPGPNYRPG---YNNFY 471
Query: 239 SAKGLKEFFTLTDLRMRLLRPALGGTYVQRE---NLYKYFYAISNIEVIGRCKCNLHANL 295
+ L+EF T +R G Y E NL +YA+ I + GRC+C+ HA+
Sbjct: 472 NTPSLQEFVKATQIRFHF-----HGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADN 526
Query: 296 CSMREGSLQCEC--EHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNC 353
C +C C E T G C +C + + +R G + + P C
Sbjct: 527 CDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKP-----------C 575
Query: 354 ECYGHSNRCSYIDFLNVV----------TCVSCKHNTRGQHCQHCRLGYYRNGSAELDDE 403
+C HS C Y ++ C C+HNT G++C+ C+ ++R A+
Sbjct: 576 QCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAI 635
Query: 404 NVCIECNCNQIGSVHDR--CNET-GFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQ 460
+VC C+C+ +G+ + C++ G C C+ +G +C+ C Y Q P+ C
Sbjct: 636 DVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCN 695
Query: 461 LLCQNGG------TCLQNQ-RCACPRGYTGVRCE 487
C G TC QN +C C G+RC+
Sbjct: 696 --CNTSGTVDGDITCHQNSGQCKCKANVIGLRCD 727
Score = 87.4 bits (215), Expect = 3e-17
Identities = 66/221 (29%), Positives = 94/221 (42%), Gaps = 45/221 (20%)
Query: 287 CKCNLHANL---CSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNA 343
C+CNLH ++ C+ G QCEC+ G C C++NF L + +
Sbjct: 747 CQCNLHGSVNKFCNPHSG--QCECKKEAKGLQCDTCRENFYG--------LDVTNCKACD 796
Query: 344 CATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLG--YYRNGSAELD 401
C TAGS C + +C CK N G+ C C G Y R ++ L
Sbjct: 797 CDTAGSLPGTVCNAKTGQCI------------CKPNVEGRQCNKCLEGNFYLRQNNSFL- 843
Query: 402 DENVCIECNCNQIGSVHDR--CNE-TGFCECREGAAGPKCDDCLPTHYWR-----QGCYP 453
C+ CNC++ G+++ CN+ TG C C+ G G +C+ C P Y Q C
Sbjct: 844 ----CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHC-- 897
Query: 454 NVCDDDQLLCQNGGTCLQ-NQRCACPRGYTGVRCEQPRCDP 493
+C+ D L G C + +C C G RC Q C P
Sbjct: 898 QMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQ--CQP 936
Score = 82.0 bits (201), Expect = 1e-15
Identities = 63/219 (28%), Positives = 88/219 (40%), Gaps = 32/219 (14%)
Query: 279 SNIEVIGRCKCNLHAN-----LCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSY 333
S I+V C C+ LC G QC C+ + +G C +C+ F
Sbjct: 633 SAIDVCKPCDCDTVGTRNGSILCDQIGG--QCNCKRHVSGRQCNQCQNGFYNLQELD--- 687
Query: 334 LPLPHG-SPNACATAGSF-GNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLG 391
P G SP C T+G+ G+ C+ +S +C CK N G C HC G
Sbjct: 688 ---PDGCSPCNCNTSGTVDGDITCHQNSGQCK------------CKANVIGLRCDHCNFG 732
Query: 392 YYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGFCECREGAAGPKCDDCLPTHYWRQG 450
+ S ++ C C CN GSV+ CN +G CEC++ A G +CD C Y
Sbjct: 733 FKFLRSF---NDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDV 789
Query: 451 CYPNVCDDDQLLCQNGGTC-LQNQRCACPRGYTGVRCEQ 488
CD D G C + +C C G +C +
Sbjct: 790 TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNK 828
Score = 63.5 bits (153), Expect = 4e-10
Identities = 46/178 (25%), Positives = 72/178 (40%), Gaps = 29/178 (16%)
Query: 272 YKYFYAISNIEVIGRCKCN----LHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRS 327
++Y I N + C+C+ L +C G QC C N G C +C+ F
Sbjct: 885 HRYNLTIDNFQHCQMCECDSLGTLPGTICDPISG--QCLCVPNRQGRRCNQCQPGFYISP 942
Query: 328 WRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQH 387
A LP +C T G+ + C+ + CV + GQ C
Sbjct: 943 GNATGCLPC------SCHTTGAVNHI--------CNSL----TGQCVCQDASIAGQRCDQ 984
Query: 388 CRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGFCECREGAAGPKCDDCLPT 444
C+ Y+ C CNC+ G++++ C+ TG C C++ G KCD C+P+
Sbjct: 985 CKDHYFGFDP----QTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPS 1038
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 126 bits (317), Expect = 4e-29
Identities = 110/454 (24%), Positives = 193/454 (42%), Gaps = 74/454 (16%)
Query: 66 ERFC-SHENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANIT 124
+R+C ++ N NP+ AHP + D + + T W S ++ + L +T
Sbjct: 316 QRYCIPNDAGDTADNRVSRLNPE-AHPLSFVNDND---VGTSWVSNVFTNI-TQLNQGVT 370
Query: 125 LSWNKTVELTDD------VVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMS 178
+S V+L + +++ F +PT + +++ +N W+ +Q++A +C AFGM
Sbjct: 371 IS----VDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNC-GAFGM- 424
Query: 179 ARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLE 238
+ D+ + L ++ ++ +V F + + GP+ R Y
Sbjct: 425 -KNNGDLEKPDSVNCLQLSNFTPYSRG----NVTFSI-----LTPGPNYRPG---YNNFY 471
Query: 239 SAKGLKEFFTLTDLRMRLLRPALGGTYVQRE---NLYKYFYAISNIEVIGRCKCNLHANL 295
+ L+EF T +R G Y E NL +YA+ I + GRC+C+ HA+
Sbjct: 472 NTPSLQEFVKATQIRFHF-----HGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADN 526
Query: 296 CSMREGSLQCEC--EHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNC 353
C +C C E T G C +C + + +R G + + P C
Sbjct: 527 CDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKP-----------C 575
Query: 354 ECYGHSNRCSYIDFLNVV----------TCVSCKHNTRGQHCQHCRLGYYRNGSAELDDE 403
+C HS C Y ++ C C+HNT G++C+ C+ ++R A+
Sbjct: 576 QCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAI 635
Query: 404 NVCIECNCNQIGSVHDR--CNET-GFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQ 460
+VC C+C+ +G+ + C++ G C C+ +G +C+ C Y Q P+ C
Sbjct: 636 DVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCN 695
Query: 461 LLCQNGG------TCLQNQ-RCACPRGYTGVRCE 487
C G TC QN +C C G+RC+
Sbjct: 696 --CNTSGTVDGDITCHQNSGQCKCKANVIGLRCD 727
Score = 87.4 bits (215), Expect = 3e-17
Identities = 66/221 (29%), Positives = 94/221 (42%), Gaps = 45/221 (20%)
Query: 287 CKCNLHANL---CSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNA 343
C+CNLH ++ C+ G QCEC+ G C C++NF L + +
Sbjct: 747 CQCNLHGSVNKFCNPHSG--QCECKKEAKGLQCDTCRENFYG--------LDVTNCKACD 796
Query: 344 CATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLG--YYRNGSAELD 401
C TAGS C + +C CK N G+ C C G Y R ++ L
Sbjct: 797 CDTAGSLPGTVCNAKTGQCI------------CKPNVEGRQCNKCLEGNFYLRQNNSFL- 843
Query: 402 DENVCIECNCNQIGSVHDR--CNE-TGFCECREGAAGPKCDDCLPTHYWR-----QGCYP 453
C+ CNC++ G+++ CN+ TG C C+ G G +C+ C P Y Q C
Sbjct: 844 ----CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHC-- 897
Query: 454 NVCDDDQLLCQNGGTCLQ-NQRCACPRGYTGVRCEQPRCDP 493
+C+ D L G C + +C C G RC Q C P
Sbjct: 898 QMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQ--CQP 936
Score = 82.0 bits (201), Expect = 1e-15
Identities = 63/219 (28%), Positives = 88/219 (40%), Gaps = 32/219 (14%)
Query: 279 SNIEVIGRCKCNLHAN-----LCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSY 333
S I+V C C+ LC G QC C+ + +G C +C+ F
Sbjct: 633 SAIDVCKPCDCDTVGTRNGSILCDQIGG--QCNCKRHVSGRQCNQCQNGFYNLQELD--- 687
Query: 334 LPLPHG-SPNACATAGSF-GNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLG 391
P G SP C T+G+ G+ C+ +S +C CK N G C HC G
Sbjct: 688 ---PDGCSPCNCNTSGTVDGDITCHQNSGQCK------------CKANVIGLRCDHCNFG 732
Query: 392 YYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGFCECREGAAGPKCDDCLPTHYWRQG 450
+ S ++ C C CN GSV+ CN +G CEC++ A G +CD C Y
Sbjct: 733 FKFLRSF---NDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDV 789
Query: 451 CYPNVCDDDQLLCQNGGTC-LQNQRCACPRGYTGVRCEQ 488
CD D G C + +C C G +C +
Sbjct: 790 TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNK 828
Score = 63.5 bits (153), Expect = 4e-10
Identities = 46/178 (25%), Positives = 72/178 (40%), Gaps = 29/178 (16%)
Query: 272 YKYFYAISNIEVIGRCKCN----LHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRS 327
++Y I N + C+C+ L +C G QC C N G C +C+ F
Sbjct: 885 HRYNLTIDNFQHCQMCECDSLGTLPGTICDPISG--QCLCVPNRQGRRCNQCQPGFYISP 942
Query: 328 WRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQH 387
A LP +C T G+ + C+ + CV + GQ C
Sbjct: 943 GNATGCLPC------SCHTTGAVNHI--------CNSL----TGQCVCQDASIAGQRCDQ 984
Query: 388 CRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGFCECREGAAGPKCDDCLPT 444
C+ Y+ C CNC+ G++++ C+ TG C C++ G KCD C+P+
Sbjct: 985 CKDHYFGFDP----QTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPS 1038
>gi|24308065 netrin 5 [Homo sapiens]
Length = 489
Score = 115 bits (287), Expect = 1e-25
Identities = 56/167 (33%), Positives = 82/167 (49%), Gaps = 19/167 (11%)
Query: 285 GRCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 344
GRC+C+ HA C+ R +C C H+TTGP C C+ + R WR P P+ C
Sbjct: 155 GRCQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWR-----PATPRHPHPC 209
Query: 345 ATAGSFGNCECYGHSNRCSYIDFLNVVT-------CVSCKHNTRGQHCQHCRLGYYRNGS 397
C C H+ RC + L ++ C C+H+T G+HC +C+ G++R+ S
Sbjct: 210 LP------CSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPS 263
Query: 398 AELDDENVCIECNCNQIGSVHDRCNET-GFCECREGAAGPKCDDCLP 443
+ C C C+ IG+ CN+T G C C+ G G C+ C P
Sbjct: 264 QPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGP 310
Score = 79.7 bits (195), Expect = 6e-15
Identities = 70/234 (29%), Positives = 91/234 (38%), Gaps = 45/234 (19%)
Query: 309 HNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFL 368
H+T GP ++ A S+L + G A AG G C+C+GH+ RC+
Sbjct: 124 HSTPGP-----------KATVAASHLRVEFGGQAGLAAAGLRGRCQCHGHAARCA--ARA 170
Query: 369 NVVTCVSCKHNTRGQHCQHCRLGY--YRNGSAELDDENVCIECNCNQIGSVHDRC----- 421
C C+H+T G C+ CR + + A + C+ C+CNQ RC
Sbjct: 171 RPPRC-HCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHAR---RCRFNSE 226
Query: 422 -------NETGFCE-CREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQ------NGG 467
G CE CR AG C C P +WR P CQ GG
Sbjct: 227 LFRLSGGRSGGVCERCRHHTAGRHCHYCQP-GFWRDPSQPIFSRRACRACQCHPIGATGG 285
Query: 468 TCLQNQ-RCACPRGYTGVRCEQPRCDPADDDG---GLDCDRAPGAAPRPATLLG 517
TC Q +C C G TG+ C RC P + C R P A AT G
Sbjct: 286 TCNQTSGQCTCKLGVTGLTCN--RCGPGYQQSRSPRMPCQRIPEATTTLATTPG 337
>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
Length = 1111
Score = 97.4 bits (241), Expect = 3e-20
Identities = 53/160 (33%), Positives = 76/160 (47%), Gaps = 21/160 (13%)
Query: 353 CECYGHSNRCSYIDFLNVVT-----CVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCI 407
C+C G S +C + L+ T C++C NT G HC+ C+ G+YR+ + + C+
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR-----ERDRCL 82
Query: 408 ECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGG 467
CNCN GS+ RC+ +G C C+ G G +CD CLP + C DQ L +
Sbjct: 83 PCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLLDSKC 139
Query: 468 TC--------LQNQRCACPRGYTGVRCEQPRCDPADDDGG 499
C RC C TG RC++ R + DGG
Sbjct: 140 DCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGG 179
Score = 63.2 bits (152), Expect = 6e-10
Identities = 41/141 (29%), Positives = 54/141 (38%), Gaps = 29/141 (20%)
Query: 307 CEHNTTGPDCGKCKKNFRTRSWRAGSYLPLP---HGSPNACATAGSFGNCECYGH----- 358
C TG C C A Y P HG C C+C +
Sbjct: 484 CPPGVTGARCELC----------ADGYFGDPFGEHGPVRPCQP------CQCNNNVDPSA 527
Query: 359 SNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVH 418
S C + C+ C HNT G +C C+ GY+ + A + + C CNCN +GS
Sbjct: 528 SGNCDRL----TGRCLKCIHNTAGIYCDQCKAGYFGDPLAP-NPADKCRACNCNPMGSEP 582
Query: 419 DRCNETGFCECREGAAGPKCD 439
C G C C+ G GP C+
Sbjct: 583 VGCRSDGTCVCKPGFGGPNCE 603
Score = 55.8 bits (133), Expect = 9e-08
Identities = 42/124 (33%), Positives = 53/124 (42%), Gaps = 14/124 (11%)
Query: 370 VVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCEC 429
V C+ C +GQ CQ C GY R+ SA L CI CNC G+ +TG C
Sbjct: 379 VEQCI-CPVGYKGQFCQDCASGYKRD-SARLGPFGTCIPCNCQGGGACDP---DTGDCYS 433
Query: 430 REGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC-----LQNQRC-ACPRGYTG 483
+ +C DC P ++ P C C NG +C + C CP G TG
Sbjct: 434 GDENPDIECADC-PIGFYNDPHDPRSC--KPCPCHNGFSCSVMPETEEVVCNNCPPGVTG 490
Query: 484 VRCE 487
RCE
Sbjct: 491 ARCE 494
Score = 55.8 bits (133), Expect = 9e-08
Identities = 51/195 (26%), Positives = 67/195 (34%), Gaps = 15/195 (7%)
Query: 303 LQCECEHN-TTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNR 361
+ C C+ PD G C P G N S C C+ +
Sbjct: 414 IPCNCQGGGACDPDTGDCYSGDENPDIECAD---CPIGFYNDPHDPRSCKPCPCHNGFS- 469
Query: 362 CSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQ--IGSVHD 419
CS + V C +C G C+ C GY+ + E C C CN S
Sbjct: 470 CSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASG 529
Query: 420 RCNE-TGFC-ECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLL-CQNGGT----CLQN 472
C+ TG C +C AG CD C Y+ PN D + C G+ C +
Sbjct: 530 NCDRLTGRCLKCIHNTAGIYCDQC-KAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD 588
Query: 473 QRCACPRGYTGVRCE 487
C C G+ G CE
Sbjct: 589 GTCVCKPGFGGPNCE 603
Score = 48.1 bits (113), Expect = 2e-05
Identities = 35/127 (27%), Positives = 47/127 (37%), Gaps = 23/127 (18%)
Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346
C CN +L + + S +C C+ TG C +C F + + S C
Sbjct: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDP 143
Query: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV- 405
AG G C+ + RC CK G+ C CR GYY LD N
Sbjct: 144 AGIAGPCD----AGRC------------VCKPAVTGERCDRCRSGYY-----NLDGGNPE 182
Query: 406 -CIECNC 411
C +C C
Sbjct: 183 GCTQCFC 189
Score = 35.0 bits (79), Expect = 0.17
Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 16/59 (27%)
Query: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRC 362
+C C+ TG C +C+ Y L G+P C C CYGHS C
Sbjct: 154 RCVCKPAVTGERCDRCRSG----------YYNLDGGNPEGCT------QCFCYGHSASC 196
>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
Length = 1193
Score = 97.4 bits (241), Expect = 3e-20
Identities = 53/160 (33%), Positives = 76/160 (47%), Gaps = 21/160 (13%)
Query: 353 CECYGHSNRCSYIDFLNVVT-----CVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCI 407
C+C G S +C + L+ T C++C NT G HC+ C+ G+YR+ + + C+
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR-----ERDRCL 82
Query: 408 ECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGG 467
CNCN GS+ RC+ +G C C+ G G +CD CLP + C DQ L +
Sbjct: 83 PCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLLDSKC 139
Query: 468 TC--------LQNQRCACPRGYTGVRCEQPRCDPADDDGG 499
C RC C TG RC++ R + DGG
Sbjct: 140 DCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGG 179
Score = 63.2 bits (152), Expect = 6e-10
Identities = 41/141 (29%), Positives = 54/141 (38%), Gaps = 29/141 (20%)
Query: 307 CEHNTTGPDCGKCKKNFRTRSWRAGSYLPLP---HGSPNACATAGSFGNCECYGH----- 358
C TG C C A Y P HG C C+C +
Sbjct: 484 CPPGVTGARCELC----------ADGYFGDPFGEHGPVRPCQP------CQCNNNVDPSA 527
Query: 359 SNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVH 418
S C + C+ C HNT G +C C+ GY+ + A + + C CNCN +GS
Sbjct: 528 SGNCDRL----TGRCLKCIHNTAGIYCDQCKAGYFGDPLAP-NPADKCRACNCNPMGSEP 582
Query: 419 DRCNETGFCECREGAAGPKCD 439
C G C C+ G GP C+
Sbjct: 583 VGCRSDGTCVCKPGFGGPNCE 603
Score = 55.8 bits (133), Expect = 9e-08
Identities = 42/124 (33%), Positives = 53/124 (42%), Gaps = 14/124 (11%)
Query: 370 VVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCEC 429
V C+ C +GQ CQ C GY R+ SA L CI CNC G+ +TG C
Sbjct: 379 VEQCI-CPVGYKGQFCQDCASGYKRD-SARLGPFGTCIPCNCQGGGACDP---DTGDCYS 433
Query: 430 REGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC-----LQNQRC-ACPRGYTG 483
+ +C DC P ++ P C C NG +C + C CP G TG
Sbjct: 434 GDENPDIECADC-PIGFYNDPHDPRSC--KPCPCHNGFSCSVMPETEEVVCNNCPPGVTG 490
Query: 484 VRCE 487
RCE
Sbjct: 491 ARCE 494
Score = 55.8 bits (133), Expect = 9e-08
Identities = 51/195 (26%), Positives = 67/195 (34%), Gaps = 15/195 (7%)
Query: 303 LQCECEHN-TTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNR 361
+ C C+ PD G C P G N S C C+ +
Sbjct: 414 IPCNCQGGGACDPDTGDCYSGDENPDIECAD---CPIGFYNDPHDPRSCKPCPCHNGFS- 469
Query: 362 CSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQ--IGSVHD 419
CS + V C +C G C+ C GY+ + E C C CN S
Sbjct: 470 CSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASG 529
Query: 420 RCNE-TGFC-ECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLL-CQNGGT----CLQN 472
C+ TG C +C AG CD C Y+ PN D + C G+ C +
Sbjct: 530 NCDRLTGRCLKCIHNTAGIYCDQC-KAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD 588
Query: 473 QRCACPRGYTGVRCE 487
C C G+ G CE
Sbjct: 589 GTCVCKPGFGGPNCE 603
Score = 48.1 bits (113), Expect = 2e-05
Identities = 35/127 (27%), Positives = 47/127 (37%), Gaps = 23/127 (18%)
Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346
C CN +L + + S +C C+ TG C +C F + + S C
Sbjct: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDP 143
Query: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV- 405
AG G C+ + RC CK G+ C CR GYY LD N
Sbjct: 144 AGIAGPCD----AGRC------------VCKPAVTGERCDRCRSGYY-----NLDGGNPE 182
Query: 406 -CIECNC 411
C +C C
Sbjct: 183 GCTQCFC 189
Score = 35.0 bits (79), Expect = 0.17
Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 16/59 (27%)
Query: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRC 362
+C C+ TG C +C+ Y L G+P C C CYGHS C
Sbjct: 154 RCVCKPAVTGERCDRCRSG----------YYNLDGGNPEGCT------QCFCYGHSASC 196
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 95.5 bits (236), Expect = 1e-19
Identities = 54/176 (30%), Positives = 77/176 (43%), Gaps = 16/176 (9%)
Query: 286 RCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACA 345
RC C+ H+ C G+ Q C+H+T GP C +C+ G Y G+P C
Sbjct: 1158 RCSCHGHSEACEPETGACQ-GCQHHTEGPRCEQCQP---------GYYGDAQRGTPQDCQ 1207
Query: 346 TAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRN---GSAELDD 402
+G+ G + ++D TC +C G+HC+ C GYY N G D
Sbjct: 1208 LCPCYGD-PAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRD 1266
Query: 403 ENVC--IECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVC 456
V I CNC+ GSV +C+ G C+C+ G C C P H+ P+ C
Sbjct: 1267 SQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRPHHFHLSASNPDGC 1322
Score = 64.3 bits (155), Expect = 3e-10
Identities = 58/222 (26%), Positives = 79/222 (35%), Gaps = 44/222 (19%)
Query: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCS 363
QC C GP C C + TR+ +G YL G+ C C+GHS C
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGY-TRT-PSGLYL-------------GTCERCSCHGHSEACE 1169
Query: 364 YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC---NQIGSVHDR 420
C C+H+T G C+ C+ GYY G A+ C C C G
Sbjct: 1170 ----PETGACQGCQHHTEGPRCEQCQPGYY--GDAQRGTPQDCQLCPCYGDPAAGQAAHT 1223
Query: 421 C----NETGFCE-CREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQL------LCQNGGT- 468
C + C+ C G +G C+ C P +Y D Q+ C G+
Sbjct: 1224 CFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSV 1283
Query: 469 ---CLQNQRCACPRGYTGVRCEQPR-----CDPADDDGGLDC 502
C +C C G+ C R ++ DG L C
Sbjct: 1284 SSQCDAAGQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPC 1325
Score = 63.5 bits (153), Expect = 4e-10
Identities = 45/177 (25%), Positives = 64/177 (36%), Gaps = 26/177 (14%)
Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346
C CN HA+ C G C+HNT GP C KCK F + +A + P P A+
Sbjct: 764 CNCNGHASSCDPVYGHC-LNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDAS 822
Query: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVC 406
C ++D TC +C G+ C+ C GY N +
Sbjct: 823 RRFSDTC----------FLDTDGQATCDACAPGYTGRRCESCAPGYEGNP--------IQ 864
Query: 407 IECNCNQIGSVHDRCNETGF-------CECREGAAGPKCDDCLPTHYWRQGCYPNVC 456
C + RC+E G C C+ G C++C + P+ C
Sbjct: 865 PGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECADGSFHLSTRNPDGC 921
Score = 62.0 bits (149), Expect = 1e-09
Identities = 48/198 (24%), Positives = 75/198 (37%), Gaps = 35/198 (17%)
Query: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCS 363
+C C +G C C +F TR G YL G+ C C GH++ C
Sbjct: 730 ECRCPIGYSGLSCESCDAHF-TRV-PGGPYL-------------GTCSGCNCNGHASSCD 774
Query: 364 YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE 423
+ C++C+HNT G C C+ G++ G A C C C I + R ++
Sbjct: 775 PV----YGHCLNCQHNTEGPQCNKCKAGFF--GDAMKATATSCRPCPCPYIDASR-RFSD 827
Query: 424 TGFCE---------CREGAAGPKCDDCLPTHYW---RQGCYPNVCDDDQLLC-QNGGTCL 470
T F + C G G +C+ C P + + G + + + C + G
Sbjct: 828 TCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGT 887
Query: 471 QNQRCACPRGYTGVRCEQ 488
+ C C G C +
Sbjct: 888 SGEACRCKNNVVGRLCNE 905
Score = 58.5 bits (140), Expect = 1e-08
Identities = 49/169 (28%), Positives = 68/169 (40%), Gaps = 30/169 (17%)
Query: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCS 363
+C C G C C + R GS L L H C CEC GHS+ C
Sbjct: 1529 ECRCPPGYIGLSCQDCAPGYT----RTGSGLYLGH-----CEL------CECNGHSDLCH 1573
Query: 364 YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE 423
C C+HN G+ C+ C GYY + +A ++ C C C + + + +
Sbjct: 1574 P----ETGACSQCQHNAAGEFCELCAPGYYGDATAGTPED--CQPCAC-PLTNPENMFSR 1626
Query: 424 TGFCECREGAAGPKCDDCLP--THYWRQGCYPNVCDDDQLLCQNGGTCL 470
T CE GA G +C C P T + + C P + + GG CL
Sbjct: 1627 T--CESL-GAGGYRCTACEPGYTGQYCEQCGPGYVGNPSV---QGGQCL 1669
Score = 56.6 bits (135), Expect = 5e-08
Identities = 53/167 (31%), Positives = 66/167 (39%), Gaps = 28/167 (16%)
Query: 368 LNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGF 426
L V C SC RG CQ C GY R S C C+C+ + C ETG
Sbjct: 1121 LEVEQC-SCPPGYRGPSCQDCDTGYTRTPSGLY--LGTCERCSCH---GHSEACEPETGA 1174
Query: 427 CE-CREGAAGPKCDDCLPTHY------WRQGCYPNVCDDDQLLCQNGGTCL----QNQRC 475
C+ C+ GP+C+ C P +Y Q C C D Q TC + C
Sbjct: 1175 CQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTC 1234
Query: 476 -ACPRGYTGVRCEQPRCDP---ADDDGGLDCDRAPGAAPRPATLLGC 518
AC G++G CE RC P + G C R P P +GC
Sbjct: 1235 DACSPGHSGRHCE--RCAPGYYGNPSQGQPCQR-DSQVPGP---IGC 1275
Score = 54.3 bits (129), Expect = 3e-07
Identities = 49/139 (35%), Positives = 55/139 (39%), Gaps = 21/139 (15%)
Query: 368 LNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGF 426
L V C C G CQ C GY R GS C C CN D C+ ETG
Sbjct: 1525 LEVEEC-RCPPGYIGLSCQDCAPGYTRTGSGLYLGH--CELCECN---GHSDLCHPETGA 1578
Query: 427 C-ECREGAAGPKCDDCLPTHYWR------QGCYPNVCDDDQLLCQNGGTCLQ----NQRC 475
C +C+ AAG C+ C P +Y + C P C TC RC
Sbjct: 1579 CSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRC 1638
Query: 476 -ACPRGYTGVRCEQPRCDP 493
AC GYTG CEQ C P
Sbjct: 1639 TACEPGYTGQYCEQ--CGP 1655
Score = 46.6 bits (109), Expect = 6e-05
Identities = 30/113 (26%), Positives = 43/113 (38%), Gaps = 11/113 (9%)
Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346
C+CN H++LC G+ +C+HN G C C G Y G+P C
Sbjct: 1563 CECNGHSDLCHPETGACS-QCQHNAAGEFCELC---------APGYYGDATAGTPEDCQP 1612
Query: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAE 399
S C + C +C+ GQ+C+ C GY N S +
Sbjct: 1613 CACPLTNPENMFSRTCESLG-AGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQ 1664
Score = 42.4 bits (98), Expect = 0.001
Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 17/88 (19%)
Query: 406 CIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQN 465
C + C G HD + + C C G G +C+ H C+P C D
Sbjct: 3848 CRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALH-----CHPEACGPD------ 3896
Query: 466 GGTCL-----QNQRCACPRGYTGVRCEQ 488
TC+ + C C G +G+RCE+
Sbjct: 3897 -ATCVNRPDGRGYTCRCHLGRSGLRCEE 3923
Score = 40.0 bits (92), Expect = 0.005
Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 22/84 (26%)
Query: 420 RCNETGFCE---CREGAAGPKCDDCLPTHYW------RQGCYPNVCDDDQLLCQ------ 464
+C ++ CE C+ GA C+P + R G ++C+ ++ CQ
Sbjct: 4101 QCYDSSPCERQPCQHGAT------CMPAGEYEFQCLCRDGFKGDLCEHEENPCQLREPCL 4154
Query: 465 NGGTCLQNQRCACPRGYTGVRCEQ 488
+GGTC Q RC C G++G RC+Q
Sbjct: 4155 HGGTC-QGTRCLCLPGFSGPRCQQ 4177
Score = 33.5 bits (75), Expect = 0.49
Identities = 26/80 (32%), Positives = 30/80 (37%), Gaps = 10/80 (12%)
Query: 419 DRCNETGFCECREGAAGPKCDDCLPTHYWR--QGCYPNVCDDDQLLCQNGGTCLQNQRCA 476
D E C C G GP C DC T Y R G Y C ++ C + + A
Sbjct: 1118 DPALEVEQCSCPPGYRGPSCQDC-DTGYTRTPSGLYLGTC--ERCSCHGHSEACEPETGA 1174
Query: 477 ---CPRGYTGVRCEQPRCDP 493
C G RCEQ C P
Sbjct: 1175 CQGCQHHTEGPRCEQ--CQP 1192
Score = 30.0 bits (66), Expect = 5.5
Identities = 32/102 (31%), Positives = 33/102 (32%), Gaps = 19/102 (18%)
Query: 420 RCNETGFCECREGAAGPKCDDCLPTHYWRQG-------CYPNVCDDDQLLCQ-NGGTCLQ 471
R E C C G G C DC P Y R G C C+ LC G C Q
Sbjct: 1523 RALEVEECRCPPGYIGLSCQDCAP-GYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQ 1581
Query: 472 NQRCACPRGYTGVRCEQPRCDP---ADDDGGLDCDRAPGAAP 510
C G CE C P D G D P A P
Sbjct: 1582 -----CQHNAAGEFCE--LCAPGYYGDATAGTPEDCQPCACP 1616
>gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
Length = 639
Score = 75.5 bits (184), Expect = 1e-13
Identities = 56/203 (27%), Positives = 83/203 (40%), Gaps = 35/203 (17%)
Query: 319 CKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTC----- 373
C+ N +++ YLPL N + C CS + LNV C
Sbjct: 211 CESNLKSK------YLPLTQPVMNLRVSEAVKTEYVC-----NCSVVGSLNVNRCNQTTG 259
Query: 374 -VSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECREG 432
C+ +G HC+ C+ G+Y N ++ L C C+C+ G++ CN +G C+C+ G
Sbjct: 260 QCECRPGYQGLHCETCKEGFYLNYTSGL-----CQPCDCSPHGALSIPCNSSGKCQCKVG 314
Query: 433 AAGPKCDDCLPTHYW--RQGCYPNVCDDDQLLCQN-GGTCLQNQRCACPRGYTGVRCEQP 489
G CD C +Y + GC P C++ C G CL C G CE+
Sbjct: 315 VIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLN-----CQENSKGNHCEE- 368
Query: 490 RCDPA---DDDGGLDCDRAPGAA 509
C D +C R P +A
Sbjct: 369 -CKEGFYQSPDATKECLRCPCSA 390
Score = 73.2 bits (178), Expect = 6e-13
Identities = 53/193 (27%), Positives = 81/193 (41%), Gaps = 50/193 (25%)
Query: 278 ISNIEVIGRCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPL- 336
+ N V+G +L+ N C+ G QCEC G C CK+ F ++ +G P
Sbjct: 240 VCNCSVVG----SLNVNRCNQTTG--QCECRPGYQGLHCETCKEGFYL-NYTSGLCQPCD 292
Query: 337 --PHGSPNACATAGSFGNCEC----------------YGHS----------NRCSYIDFL 368
PHG+ S G C+C YG S NR + D L
Sbjct: 293 CSPHGA--LSIPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDAL 350
Query: 369 NVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCE 428
C++C+ N++G HC+ C+ G+Y++ A + C+ C C+ + S TG C
Sbjct: 351 -TGACLNCQENSKGNHCEECKEGFYQSPDATKE----CLRCPCSAVTS-------TGSCS 398
Query: 429 CREGAAGPKCDDC 441
+ P+CD C
Sbjct: 399 IKSSELEPECDQC 411
Score = 52.4 bits (124), Expect = 1e-06
Identities = 46/189 (24%), Positives = 74/189 (39%), Gaps = 38/189 (20%)
Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346
C+CN + C G+ C+ N+ G C +CK+ F L P C+
Sbjct: 338 CQCNNRSASCDALTGAC-LNCQENSKGNHCEECKEGFYQSPDATKECLRCP------CSA 390
Query: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVC 406
S G+C S + S ++ C CK G +C C GYY + +++C
Sbjct: 391 VTSTGSC-----SIKSSELE----PECDQCKDGYIGPNCNKCENGYY-------NFDSIC 434
Query: 407 IECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCL--PTHYWRQGCYPNVCDDDQLLCQ 464
+C C+ G V D C+ G +C +CL T +W + C D +
Sbjct: 435 RKCQCH--GHV-DPVKTPKICKPESG----ECINCLHNTTGFWCENCLEGYVHDLE---- 483
Query: 465 NGGTCLQNQ 473
G C++ +
Sbjct: 484 --GNCIKKE 490
Score = 45.8 bits (107), Expect = 1e-04
Identities = 28/114 (24%), Positives = 47/114 (41%), Gaps = 27/114 (23%)
Query: 286 RCKCNLHANL--CSMREGSLQCECEH---NTTGPDCGKCKKNFRTRSWRAGSYLPLPHGS 340
RC C+ + CS++ L+ EC+ GP+C KC+ + +
Sbjct: 385 RCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGY--------------YNF 430
Query: 341 PNACATAGSFGNCECYGHSNRCSYIDFLNVVT--CVSCKHNTRGQHCQHCRLGY 392
+ C C+C+GH + + C++C HNT G C++C GY
Sbjct: 431 DSICR------KCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 478
>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
Length = 1668
Score = 74.7 bits (182), Expect = 2e-13
Identities = 53/179 (29%), Positives = 71/179 (39%), Gaps = 26/179 (14%)
Query: 353 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412
C C GHSN+C D + CV+C+HNT G+HC+ C+ GYY N C C C
Sbjct: 78 CNCNGHSNQCQ--DGSGI--CVNCQHNTAGEHCERCQEGYYGNAV-----HGSCRACPCP 128
Query: 413 QIGSVHDRCNETG---FCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC 469
S C G C C+ G G +C+ C P ++ + C C +C
Sbjct: 129 HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP----C----SC 180
Query: 470 LQNQRCACPRGYTGVRCEQPRCDPADDDGGLDCDRAPGAAPRPATLLGCLLLLGLAARL 528
N + TG Q +P D +CD TLL L +G RL
Sbjct: 181 NSNGQLGSCHPLTGDCINQ---EPKDSSPAEECDDCDSCV---MTLLNDLATMGEQLRL 233
Score = 69.3 bits (168), Expect = 8e-12
Identities = 51/162 (31%), Positives = 67/162 (41%), Gaps = 33/162 (20%)
Query: 287 CKCNLHANLCSMREGSLQC-ECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACA 345
C CN H+N C ++GS C C+HNT G C +C++ G Y HGS AC
Sbjct: 78 CNCNGHSNQC--QDGSGICVNCQHNTAGEHCERCQE---------GYYGNAVHGSCRACP 126
Query: 346 T--AGSFG-NCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDD 402
SF C G RC SCK G C+ C GY+ N
Sbjct: 127 CPHTNSFATGCVVNGGDVRC------------SCKAGYTGTQCERCAPGYFGNPQ---KF 171
Query: 403 ENVCIECNCN---QIGSVHDRCNETGFCECREGAAGPKCDDC 441
C C+CN Q+GS H + E ++ + +CDDC
Sbjct: 172 GGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213
Score = 53.1 bits (126), Expect = 6e-07
Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 23/151 (15%)
Query: 354 ECYGHSNRCSYIDFLNVVTCVSCKHN-TRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412
+C G+S++ + FL + + + Q C GYYR+ C+ CNCN
Sbjct: 24 QCLGYSSQQQRVPFLQPPGQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGR--CVPCNCN 81
Query: 413 QIGSVHDRCNETGFC-ECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGT--- 468
G + + +G C C+ AG C+ C ++G Y N C T
Sbjct: 82 --GHSNQCQDGSGICVNCQHNTAGEHCERC------QEGYYGNAVHGSCRACPCPHTNSF 133
Query: 469 ---CLQN---QRCACPRGYTGVRCEQPRCDP 493
C+ N RC+C GYTG +CE RC P
Sbjct: 134 ATGCVVNGGDVRCSCKAGYTGTQCE--RCAP 162
>gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
Length = 1724
Score = 74.7 bits (182), Expect = 2e-13
Identities = 53/179 (29%), Positives = 71/179 (39%), Gaps = 26/179 (14%)
Query: 353 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412
C C GHSN+C D + CV+C+HNT G+HC+ C+ GYY N C C C
Sbjct: 78 CNCNGHSNQCQ--DGSGI--CVNCQHNTAGEHCERCQEGYYGNAV-----HGSCRACPCP 128
Query: 413 QIGSVHDRCNETG---FCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC 469
S C G C C+ G G +C+ C P ++ + C C +C
Sbjct: 129 HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP----C----SC 180
Query: 470 LQNQRCACPRGYTGVRCEQPRCDPADDDGGLDCDRAPGAAPRPATLLGCLLLLGLAARL 528
N + TG Q +P D +CD TLL L +G RL
Sbjct: 181 NSNGQLGSCHPLTGDCINQ---EPKDSSPAEECDDCDSCV---MTLLNDLATMGEQLRL 233
Score = 69.3 bits (168), Expect = 8e-12
Identities = 51/162 (31%), Positives = 67/162 (41%), Gaps = 33/162 (20%)
Query: 287 CKCNLHANLCSMREGSLQC-ECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACA 345
C CN H+N C ++GS C C+HNT G C +C++ G Y HGS AC
Sbjct: 78 CNCNGHSNQC--QDGSGICVNCQHNTAGEHCERCQE---------GYYGNAVHGSCRACP 126
Query: 346 T--AGSFG-NCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDD 402
SF C G RC SCK G C+ C GY+ N
Sbjct: 127 CPHTNSFATGCVVNGGDVRC------------SCKAGYTGTQCERCAPGYFGNPQ---KF 171
Query: 403 ENVCIECNCN---QIGSVHDRCNETGFCECREGAAGPKCDDC 441
C C+CN Q+GS H + E ++ + +CDDC
Sbjct: 172 GGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213
Score = 53.1 bits (126), Expect = 6e-07
Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 23/151 (15%)
Query: 354 ECYGHSNRCSYIDFLNVVTCVSCKHN-TRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412
+C G+S++ + FL + + + Q C GYYR+ C+ CNCN
Sbjct: 24 QCLGYSSQQQRVPFLQPPGQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGR--CVPCNCN 81
Query: 413 QIGSVHDRCNETGFC-ECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGT--- 468
G + + +G C C+ AG C+ C ++G Y N C T
Sbjct: 82 --GHSNQCQDGSGICVNCQHNTAGEHCERC------QEGYYGNAVHGSCRACPCPHTNSF 133
Query: 469 ---CLQN---QRCACPRGYTGVRCEQPRCDP 493
C+ N RC+C GYTG +CE RC P
Sbjct: 134 ATGCVVNGGDVRCSCKAGYTGTQCE--RCAP 162
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.466
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,183,621
Number of Sequences: 37866
Number of extensions: 1313079
Number of successful extensions: 5617
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 104
Number of HSP's successfully gapped in prelim test: 181
Number of HSP's that attempted gapping in prelim test: 3079
Number of HSP's gapped (non-prelim): 1234
length of query: 530
length of database: 18,247,518
effective HSP length: 107
effective length of query: 423
effective length of database: 14,195,856
effective search space: 6004847088
effective search space used: 6004847088
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.