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Search of human proteins with 189491744
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|189491744 vacuolar protein sorting 53 isoform 1 [Homo
sapiens]
(832 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|189491744 vacuolar protein sorting 53 isoform 1 [Homo sapiens] 1640 0.0
gi|21361728 vacuolar protein sorting 53 isoform 2 [Homo sapiens] 1313 0.0
gi|239751532 PREDICTED: similar to vacuolar protein sorting 53 (... 118 3e-26
gi|239746043 PREDICTED: hypothetical protein XP_002343642 [Homo ... 118 3e-26
gi|122937396 coiled-coil domain containing 150 [Homo sapiens] 41 0.004
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 40 0.012
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 39 0.015
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 38 0.034
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens] 37 0.058
gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] 36 0.17
gi|7705415 hook homolog 1 [Homo sapiens] 36 0.17
gi|33946313 ninein isoform 4 [Homo sapiens] 36 0.17
gi|33946321 ninein isoform 5 [Homo sapiens] 36 0.17
gi|148536871 ninein isoform 1 [Homo sapiens] 36 0.17
gi|148536869 ninein isoform 2 [Homo sapiens] 36 0.17
gi|109134347 NY-REN-58 antigen [Homo sapiens] 36 0.17
gi|109134355 NY-REN-58 antigen [Homo sapiens] 36 0.17
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 36 0.17
gi|119395750 keratin 1 [Homo sapiens] 35 0.22
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 35 0.22
gi|16262452 cingulin [Homo sapiens] 35 0.22
gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens] 35 0.29
gi|62821790 leucine zipper protein 2 [Homo sapiens] 35 0.29
gi|116686122 kinesin family member 4 [Homo sapiens] 35 0.29
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ... 35 0.29
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ... 35 0.29
gi|150010604 kinesin family member 4B [Homo sapiens] 35 0.37
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 34 0.49
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 34 0.49
gi|110349797 homer 2 isoform 4 [Homo sapiens] 34 0.49
>gi|189491744 vacuolar protein sorting 53 isoform 1 [Homo sapiens]
Length = 832
Score = 1640 bits (4246), Expect = 0.0
Identities = 832/832 (100%), Positives = 832/832 (100%)
Query: 1 MMEEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLAN 60
MMEEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLAN
Sbjct: 1 MMEEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLAN 60
Query: 61 IDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEK 120
IDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEK
Sbjct: 61 IDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEK 120
Query: 121 SEQMVKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTRRRQYGEVANLLQG 180
SEQMVKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTRRRQYGEVANLLQG
Sbjct: 121 SEQMVKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTRRRQYGEVANLLQG 180
Query: 181 VMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQILADFEEAFPSQGTKRPGGPSNVLRD 240
VMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQILADFEEAFPSQGTKRPGGPSNVLRD
Sbjct: 181 VMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQILADFEEAFPSQGTKRPGGPSNVLRD 240
Query: 241 ACLVANILDPRIKQEIIKKFIKQHLSEYLVLFQENQDVAWLDKIDRRYAWIKRQLVDYEE 300
ACLVANILDPRIKQEIIKKFIKQHLSEYLVLFQENQDVAWLDKIDRRYAWIKRQLVDYEE
Sbjct: 241 ACLVANILDPRIKQEIIKKFIKQHLSEYLVLFQENQDVAWLDKIDRRYAWIKRQLVDYEE 300
Query: 301 KYGRMFPREWCMAERIAVEFCHVTRAELAKIMRTRAKEIEVKLLLFAIQRTTNFEGFLAK 360
KYGRMFPREWCMAERIAVEFCHVTRAELAKIMRTRAKEIEVKLLLFAIQRTTNFEGFLAK
Sbjct: 301 KYGRMFPREWCMAERIAVEFCHVTRAELAKIMRTRAKEIEVKLLLFAIQRTTNFEGFLAK 360
Query: 361 RFSGCTLTDGTLKKLESPPPSTNPFLEDEPTPEMEELATEKGDLDQPKKPKAPDNPFHGI 420
RFSGCTLTDGTLKKLESPPPSTNPFLEDEPTPEMEELATEKGDLDQPKKPKAPDNPFHGI
Sbjct: 361 RFSGCTLTDGTLKKLESPPPSTNPFLEDEPTPEMEELATEKGDLDQPKKPKAPDNPFHGI 420
Query: 421 VSKCFEPHLYVYIESQDKNLGELIDRFVADFKAQGPPKPNTDEGGAVLPSCADLFVYYKK 480
VSKCFEPHLYVYIESQDKNLGELIDRFVADFKAQGPPKPNTDEGGAVLPSCADLFVYYKK
Sbjct: 421 VSKCFEPHLYVYIESQDKNLGELIDRFVADFKAQGPPKPNTDEGGAVLPSCADLFVYYKK 480
Query: 481 CMVQCSQLSTGEPMIALTTIFQKYLREYAWKILSGNLPKTTTSSGGLTISSLLKEKEGSE 540
CMVQCSQLSTGEPMIALTTIFQKYLREYAWKILSGNLPKTTTSSGGLTISSLLKEKEGSE
Sbjct: 481 CMVQCSQLSTGEPMIALTTIFQKYLREYAWKILSGNLPKTTTSSGGLTISSLLKEKEGSE 540
Query: 541 VAKFTLEELCLICNILSTAEYCLATTQQLEEKLKEKVDVSLIERINLTGEMDTFSTVISS 600
VAKFTLEELCLICNILSTAEYCLATTQQLEEKLKEKVDVSLIERINLTGEMDTFSTVISS
Sbjct: 541 VAKFTLEELCLICNILSTAEYCLATTQQLEEKLKEKVDVSLIERINLTGEMDTFSTVISS 600
Query: 601 SIQLLVQDLDAACDPALTAMSKMQWQNVEHVGDQSPYVTSVILHIKQNVPIIRDNLASTR 660
SIQLLVQDLDAACDPALTAMSKMQWQNVEHVGDQSPYVTSVILHIKQNVPIIRDNLASTR
Sbjct: 601 SIQLLVQDLDAACDPALTAMSKMQWQNVEHVGDQSPYVTSVILHIKQNVPIIRDNLASTR 660
Query: 661 KYFTQFCVKFANSFIPKFITHLFKCKPISMVGAEQLLLDTHSLKMVLLDLPSISSQVVRK 720
KYFTQFCVKFANSFIPKFITHLFKCKPISMVGAEQLLLDTHSLKMVLLDLPSISSQVVRK
Sbjct: 661 KYFTQFCVKFANSFIPKFITHLFKCKPISMVGAEQLLLDTHSLKMVLLDLPSISSQVVRK 720
Query: 721 APASYTKIVVKGMTRAEMILKVVMAPHEPLVVFVDNYIKLLTDCNTETFQKILDMKGLKR 780
APASYTKIVVKGMTRAEMILKVVMAPHEPLVVFVDNYIKLLTDCNTETFQKILDMKGLKR
Sbjct: 721 APASYTKIVVKGMTRAEMILKVVMAPHEPLVVFVDNYIKLLTDCNTETFQKILDMKGLKR 780
Query: 781 SEQSSMLELLRQRLPAPPSGAESSGSLSLTAPTPEQESSRIRKLEKLIKKRL 832
SEQSSMLELLRQRLPAPPSGAESSGSLSLTAPTPEQESSRIRKLEKLIKKRL
Sbjct: 781 SEQSSMLELLRQRLPAPPSGAESSGSLSLTAPTPEQESSRIRKLEKLIKKRL 832
>gi|21361728 vacuolar protein sorting 53 isoform 2 [Homo sapiens]
Length = 670
Score = 1313 bits (3399), Expect = 0.0
Identities = 666/696 (95%), Positives = 667/696 (95%), Gaps = 29/696 (4%)
Query: 1 MMEEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLAN 60
MMEEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLAN
Sbjct: 1 MMEEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLAN 60
Query: 61 IDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEK 120
IDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQ
Sbjct: 61 IDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQ------------------------- 95
Query: 121 SEQMVKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTRRRQYGEVANLLQG 180
VKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTRRRQYGEVANLLQG
Sbjct: 96 ----VKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTRRRQYGEVANLLQG 151
Query: 181 VMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQILADFEEAFPSQGTKRPGGPSNVLRD 240
VMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQILADFEEAFPSQGTKRPGGPSNVLRD
Sbjct: 152 VMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQILADFEEAFPSQGTKRPGGPSNVLRD 211
Query: 241 ACLVANILDPRIKQEIIKKFIKQHLSEYLVLFQENQDVAWLDKIDRRYAWIKRQLVDYEE 300
ACLVANILDPRIKQEIIKKFIKQHLSEYLVLFQENQDVAWLDKIDRRYAWIKRQLVDYEE
Sbjct: 212 ACLVANILDPRIKQEIIKKFIKQHLSEYLVLFQENQDVAWLDKIDRRYAWIKRQLVDYEE 271
Query: 301 KYGRMFPREWCMAERIAVEFCHVTRAELAKIMRTRAKEIEVKLLLFAIQRTTNFEGFLAK 360
KYGRMFPREWCMAERIAVEFCHVTRAELAKIMRTRAKEIEVKLLLFAIQRTTNFEGFLAK
Sbjct: 272 KYGRMFPREWCMAERIAVEFCHVTRAELAKIMRTRAKEIEVKLLLFAIQRTTNFEGFLAK 331
Query: 361 RFSGCTLTDGTLKKLESPPPSTNPFLEDEPTPEMEELATEKGDLDQPKKPKAPDNPFHGI 420
RFSGCTLTDGTLKKLESPPPSTNPFLEDEPTPEMEELATEKGDLDQPKKPKAPDNPFHGI
Sbjct: 332 RFSGCTLTDGTLKKLESPPPSTNPFLEDEPTPEMEELATEKGDLDQPKKPKAPDNPFHGI 391
Query: 421 VSKCFEPHLYVYIESQDKNLGELIDRFVADFKAQGPPKPNTDEGGAVLPSCADLFVYYKK 480
VSKCFEPHLYVYIESQDKNLGELIDRFVADFKAQGPPKPNTDEGGAVLPSCADLFVYYKK
Sbjct: 392 VSKCFEPHLYVYIESQDKNLGELIDRFVADFKAQGPPKPNTDEGGAVLPSCADLFVYYKK 451
Query: 481 CMVQCSQLSTGEPMIALTTIFQKYLREYAWKILSGNLPKTTTSSGGLTISSLLKEKEGSE 540
CMVQCSQLSTGEPMIALTTIFQKYLREYAWKILSGNLPKTTTSSGGLTISSLLKEKEGSE
Sbjct: 452 CMVQCSQLSTGEPMIALTTIFQKYLREYAWKILSGNLPKTTTSSGGLTISSLLKEKEGSE 511
Query: 541 VAKFTLEELCLICNILSTAEYCLATTQQLEEKLKEKVDVSLIERINLTGEMDTFSTVISS 600
VAKFTLEELCLICNILSTAEYCLATTQQLEEKLKEKVDVSLIERINLTGEMDTFSTVISS
Sbjct: 512 VAKFTLEELCLICNILSTAEYCLATTQQLEEKLKEKVDVSLIERINLTGEMDTFSTVISS 571
Query: 601 SIQLLVQDLDAACDPALTAMSKMQWQNVEHVGDQSPYVTSVILHIKQNVPIIRDNLASTR 660
SIQLLVQDLDAACDPALTAMSKMQWQNVEHVGDQSPYVTSVILHIKQNVPIIRDNLASTR
Sbjct: 572 SIQLLVQDLDAACDPALTAMSKMQWQNVEHVGDQSPYVTSVILHIKQNVPIIRDNLASTR 631
Query: 661 KYFTQFCVKFANSFIPKFITHLFKCKPISMVGAEQL 696
KYFTQFCVKFANSFIPKFITHLFKCKPISMVGAEQ+
Sbjct: 632 KYFTQFCVKFANSFIPKFITHLFKCKPISMVGAEQV 667
>gi|239751532 PREDICTED: similar to vacuolar protein sorting 53
(yeast) (predicted) [Homo sapiens]
Length = 188
Score = 118 bits (295), Expect = 3e-26
Identities = 68/103 (66%), Positives = 75/103 (72%), Gaps = 4/103 (3%)
Query: 731 KGMTRAEMIL-KVVMAPHEPLVVFVDNYIKLLTDCNTETFQKILDMKGLKRSEQSSMLEL 789
KG+ R +L +VV AP E LVV VDNYIKL TDCNTE F+KILDMKG+KR++QSSMLE
Sbjct: 37 KGIQRCRWLLAEVVTAPQELLVVLVDNYIKLFTDCNTEAFRKILDMKGMKRNKQSSMLEF 96
Query: 790 LRQRLPAPPSGAESSGSLSLTAPTPEQESSRIRKLEKLIKKRL 832
L LP P G ESS SLSL PTPEQE S I KLIKKRL
Sbjct: 97 LHLPLPMLPLGVESSSSLSLMPPTPEQELSGIC---KLIKKRL 136
>gi|239746043 PREDICTED: hypothetical protein XP_002343642 [Homo
sapiens]
Length = 188
Score = 118 bits (295), Expect = 3e-26
Identities = 68/103 (66%), Positives = 75/103 (72%), Gaps = 4/103 (3%)
Query: 731 KGMTRAEMIL-KVVMAPHEPLVVFVDNYIKLLTDCNTETFQKILDMKGLKRSEQSSMLEL 789
KG+ R +L +VV AP E LVV VDNYIKL TDCNTE F+KILDMKG+KR++QSSMLE
Sbjct: 37 KGIQRCRWLLAEVVTAPQELLVVLVDNYIKLFTDCNTEAFRKILDMKGMKRNKQSSMLEF 96
Query: 790 LRQRLPAPPSGAESSGSLSLTAPTPEQESSRIRKLEKLIKKRL 832
L LP P G ESS SLSL PTPEQE S I KLIKKRL
Sbjct: 97 LHLPLPMLPLGVESSSSLSLMPPTPEQELSGIC---KLIKKRL 136
>gi|122937396 coiled-coil domain containing 150 [Homo sapiens]
Length = 1101
Score = 41.2 bits (95), Expect = 0.004
Identities = 56/231 (24%), Positives = 97/231 (41%), Gaps = 33/231 (14%)
Query: 4 EEELEFVEELEAVLQLTPEV--QLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLANI 61
E E +E L Q E ++A +V + LD A+F +VE T Q LA +
Sbjct: 822 ELHAERIEALRKQFQTERETTKKVAQREVAELKKALDEANFRSVEVSRTNRELRQKLAEL 881
Query: 62 DEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEKS 121
++++ + KI+ I+ + + N Q+ E K I++ +++ IKD+ +K
Sbjct: 882 EKILESNKEKIKNQKTQIKLHLSAKANNAQN-----IERMKQIEKELKQMELIKDQYQKK 936
Query: 122 --------EQMVKEITRDIKQLDH-AKRHLTTSI-TTLNHLHMLAGGVDSLEAMTRRRQY 171
++ V E+T K++ AK S+ LH LEA + RQ
Sbjct: 937 NYEQSLSIQRFVCEMTNLQKEMQMLAKSQYDASVRNKQQELH--------LEAERKIRQ- 987
Query: 172 GEVANLLQGVMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQILADFEEA 222
E+ N Q + + H K ++ +E + +QI A+ EEA
Sbjct: 988 -ELENRCQELEETVRHLKK------CKEATENTLKEASVESEQITANLEEA 1031
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 39.7 bits (91), Expect = 0.012
Identities = 44/179 (24%), Positives = 77/179 (43%), Gaps = 24/179 (13%)
Query: 4 EEELEFVEELEAVLQLT-PEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLANID 62
+E+L VE +LQ E+ +EQ S+ ++ +A E + L SL N
Sbjct: 1671 KEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTK 1730
Query: 63 EVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEKSE 122
+ K+ + +L + V++ N + ++A+ +A ++L K +D + E
Sbjct: 1731 K---KLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEEL----KKEQDTSAHLE 1783
Query: 123 QMVKEITRDIKQLDHAKRHLTTSITTLNHLHMLA--GG---VDSLEAMTRRRQYGEVAN 176
+M K + + +K L H L+ LA GG + LEA R + GEV N
Sbjct: 1784 RMKKNLEQTVKDLQH----------RLDEAEQLALKGGKKQIQKLEARVRELE-GEVEN 1831
Score = 34.3 bits (77), Expect = 0.49
Identities = 42/175 (24%), Positives = 78/175 (44%), Gaps = 18/175 (10%)
Query: 46 EYINTLFPTEQSLANIDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQ 105
E+ T +S A E+ K+ ++ +D ++ V+ + + D + E+ K
Sbjct: 858 EFQKTKDELAKSEAKRKELEEKMVTLLKEKND-LQLQVQSEADSLADAEERCEQLIKNKI 916
Query: 106 QLFGKIKDIKDKAEKSEQMVKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAM 165
QL KIK++ ++AE+ E++ E+T ++L+ L I + L + V+ +
Sbjct: 917 QLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDI---DDLELTLAKVEKEKHA 973
Query: 166 TRRRQYGEVANLLQGVMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQILADFE 220
T + V NL + + + E I +LS+ KA Q E QQ L D +
Sbjct: 974 TENK----VKNLTEEMAGLDE---------TIAKLSKEKKALQ-ETHQQTLDDLQ 1014
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 39.3 bits (90), Expect = 0.015
Identities = 34/138 (24%), Positives = 64/138 (46%), Gaps = 14/138 (10%)
Query: 4 EEELEFVEELEAVLQLT-PEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLANID 62
+E+L VE +LQ E++ +EQ S+ ++ +A E + L SL N
Sbjct: 1672 KEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTK 1731
Query: 63 EVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEKS- 121
++L+ +I + ++ Q+ R A E+A+KAI +++K + + S
Sbjct: 1732 ----------KKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSA 1781
Query: 122 --EQMVKEITRDIKQLDH 137
E+M K + + +K L H
Sbjct: 1782 HLERMKKNLEQTVKDLQH 1799
Score = 32.7 bits (73), Expect = 1.4
Identities = 39/184 (21%), Positives = 79/184 (42%), Gaps = 34/184 (18%)
Query: 54 TEQSLANIDEVVNKIRLKIRRLD-----------------DNIRTVVRGQTNVGQDGRQA 96
TE+ +AN+ E K + ++ + + ++++ V+ + + D +
Sbjct: 849 TEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEER 908
Query: 97 LEEAQKAIQQLFGKIKDIKDKAEKSEQMVKEITRDIKQLDHAKRHLTTSITTLNHLHMLA 156
++ K QL KIK++ ++AE E++ E+T ++L+ L I + L +
Sbjct: 909 CDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI---DDLELTL 965
Query: 157 GGVDSLEAMTRRRQYGEVANLLQGVMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQIL 216
V+ + T + V NL + + + E I +L++ KA Q E QQ L
Sbjct: 966 AKVEKEKHATENK----VKNLTEEMAGLDE---------TIAKLTKEKKALQ-EAHQQTL 1011
Query: 217 ADFE 220
D +
Sbjct: 1012 DDLQ 1015
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 38.1 bits (87), Expect = 0.034
Identities = 50/234 (21%), Positives = 105/234 (44%), Gaps = 35/234 (14%)
Query: 2 MEEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLANI 61
+EEE+ ++L+ EV+ E V +Q+ L++A+ A + E +A++
Sbjct: 39 LEEEQQALQKKLKGT---EDEVEKYSESVKEAQEKLEQAEKKATD-------AEADVASL 88
Query: 62 DEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEKS 121
+ + + ++ R + + T + Q LEEA+KA + +K I+++A K
Sbjct: 89 NRRIQLVEEELDRAQERLATAL-----------QKLEEAEKAADESERGMKVIENRAMKD 137
Query: 122 EQMVKEITRDIKQLDHAKRHLTTSITTL-NHLHMLAGGVDSLE-----AMTRRRQY-GEV 174
E+ ++ +K+ H + L +L G ++ E A +R RQ E+
Sbjct: 138 EEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEEL 197
Query: 175 ANLLQGVMNVLEHFHKYMG-----IPQIRQLSERVKAAQT--ELGQQILADFEE 221
+ Q + +++ +Y +I+ L E++K A+T E ++ +A E+
Sbjct: 198 RTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEK 251
Score = 33.1 bits (74), Expect = 1.1
Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 3/60 (5%)
Query: 91 QDGRQALEEAQKAIQQLFGKIKDIKDKAEKSEQMVKEITRDIKQLDHAKRHLTTSITTLN 150
+D + LEE Q+A+Q+ K+K +D+ EK + VKE ++Q + + +LN
Sbjct: 33 EDRCKQLEEEQQALQK---KLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLN 89
>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
Length = 284
Score = 37.4 bits (85), Expect = 0.058
Identities = 51/234 (21%), Positives = 103/234 (44%), Gaps = 35/234 (14%)
Query: 2 MEEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLANI 61
+EEE+ ++L+ EV+ E V +Q+ L++A+ A + E +A++
Sbjct: 39 LEEEQQALQKKLKGT---EDEVEKYSESVKEAQEKLEQAEKKATD-------AEADVASL 88
Query: 62 DEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEKS 121
+ + + ++ R + + T + Q LEEA+KA + +K I+++A K
Sbjct: 89 NRRIQLVEEELDRAQERLATAL-----------QKLEEAEKAADESERGMKVIENRAMKD 137
Query: 122 EQMVKEITRDIKQLDHAKRHLTTSITTL-NHLHMLAGGVDSLE--AMTRRRQYGEVANLL 178
E+ ++ +K+ H + L +L G ++ E A + G++ L
Sbjct: 138 EEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEEL 197
Query: 179 QGVMNVLEHFH----KYMG-----IPQIRQLSERVKAAQT--ELGQQILADFEE 221
+ V N L+ KY +I+ L E++K A+T E ++ +A E+
Sbjct: 198 KIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEK 251
Score = 33.1 bits (74), Expect = 1.1
Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 3/60 (5%)
Query: 91 QDGRQALEEAQKAIQQLFGKIKDIKDKAEKSEQMVKEITRDIKQLDHAKRHLTTSITTLN 150
+D + LEE Q+A+Q+ K+K +D+ EK + VKE ++Q + + +LN
Sbjct: 33 EDRCKQLEEEQQALQK---KLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLN 89
>gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens]
Length = 284
Score = 35.8 bits (81), Expect = 0.17
Identities = 50/223 (22%), Positives = 91/223 (40%), Gaps = 33/223 (14%)
Query: 3 EEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYI-NTLFPTEQSLANI 61
+E L+ E+ EA + + +E+ +++ L R + + + L E SL
Sbjct: 15 KENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAA 74
Query: 62 DEVVNKIRLKIRRLDDNIRTVV----RGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDK 117
+E K + L+ I+ V R Q + Q LEEA+KA + +K I+ +
Sbjct: 75 EEAAAKAEADVASLNRRIQLVEEELDRAQERLAT-ALQKLEEAEKAADESERGMKVIESR 133
Query: 118 AEKSEQMVKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTRRRQYGEVANL 177
A+K E+ ++ +K+ H +A D R+Y EVA
Sbjct: 134 AQKDEEKMEIQEIQLKEAKH-----------------IAEDAD--------RKYEEVARK 168
Query: 178 LQGVMNVLEHFHKYMGIP--QIRQLSERVKAAQTELGQQILAD 218
L + + LE + + Q+RQL E+++ L + A+
Sbjct: 169 LVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAE 211
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 35.8 bits (81), Expect = 0.17
Identities = 70/348 (20%), Positives = 136/348 (39%), Gaps = 66/348 (18%)
Query: 2 MEEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLANI 61
+E++ +EF + + L E + +++ + D+A N L T +
Sbjct: 278 LEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKA--------NKLESTVEIYRQK 329
Query: 62 DEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQA------LEEAQKAIQQLFGKIK--- 112
+ +N +R +++ L + + ++ ++ ++A LE ++ +Q L K+
Sbjct: 330 LQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSSES 389
Query: 113 --------DIKDKAEKSEQMVKEITRDIKQLDHAKR---HLTTSITTLNHLHMLAGGV-- 159
++K EK E ++KE R I+Q D K L S +HL+
Sbjct: 390 KRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATK 449
Query: 160 --DSLEAMTRRRQYGEVANLLQGVMNVLEHFHKYMGIPQIRQLSERVKAAQTELG----- 212
++L A +Y EV LQ H +K + + Q +ER++ Q +L
Sbjct: 450 SYENLAAEIMPVEYREVFIRLQ-------HENKMLRLQQEGSENERIEELQEQLEQKHRK 502
Query: 213 ------------------QQILADFEEAFPSQGTKRPGGPSNVLRDACLVANILDPRIKQ 254
QQ + D +++ QG+K G S+ L+ + +
Sbjct: 503 MNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHE 562
Query: 255 EIIKKFIKQHLSEYLVLFQENQDVAWLDKIDRRYAWIKRQLVDYEEKY 302
E+ K KQ L E L NQ+V +++++ + EE+Y
Sbjct: 563 ELQK---KQELIEDLQP-DINQNVQKINELEAALQKKDEDMKAMEERY 606
>gi|33946313 ninein isoform 4 [Homo sapiens]
Length = 2096
Score = 35.8 bits (81), Expect = 0.17
Identities = 38/167 (22%), Positives = 74/167 (44%), Gaps = 18/167 (10%)
Query: 63 EVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEKSE 122
E+ +K+R ++LD+ + + + Q N+ Q +K I L +I +++ +A +
Sbjct: 634 ELEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAVLK 693
Query: 123 QMVKEIT----RDIKQ----LDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTRRRQYGEV 174
+ E T + KQ L+ K HL + L H L + +A R + G
Sbjct: 694 EAHHEATCRHEEEKKQLQVKLEEEKTHLQEKL-RLQHEMELKARLTQAQASFEREREGLQ 752
Query: 175 ANL-----LQGVMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQIL 216
++ ++G+ LE FH+ Q+ L E+ + EL +++L
Sbjct: 753 SSAWTEEKVRGLTQELEQFHQ----EQLTSLVEKHTLEKEELRKELL 795
>gi|33946321 ninein isoform 5 [Homo sapiens]
Length = 2090
Score = 35.8 bits (81), Expect = 0.17
Identities = 38/167 (22%), Positives = 74/167 (44%), Gaps = 18/167 (10%)
Query: 63 EVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEKSE 122
E+ +K+R ++LD+ + + + Q N+ Q +K I L +I +++ +A +
Sbjct: 628 ELEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAVLK 687
Query: 123 QMVKEIT----RDIKQ----LDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTRRRQYGEV 174
+ E T + KQ L+ K HL + L H L + +A R + G
Sbjct: 688 EAHHEATCRHEEEKKQLQVKLEEEKTHLQEKL-RLQHEMELKARLTQAQASFEREREGLQ 746
Query: 175 ANL-----LQGVMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQIL 216
++ ++G+ LE FH+ Q+ L E+ + EL +++L
Sbjct: 747 SSAWTEEKVRGLTQELEQFHQ----EQLTSLVEKHTLEKEELRKELL 789
>gi|148536871 ninein isoform 1 [Homo sapiens]
Length = 2046
Score = 35.8 bits (81), Expect = 0.17
Identities = 38/167 (22%), Positives = 74/167 (44%), Gaps = 18/167 (10%)
Query: 63 EVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEKSE 122
E+ +K+R ++LD+ + + + Q N+ Q +K I L +I +++ +A +
Sbjct: 628 ELEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAVLK 687
Query: 123 QMVKEIT----RDIKQ----LDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTRRRQYGEV 174
+ E T + KQ L+ K HL + L H L + +A R + G
Sbjct: 688 EAHHEATCRHEEEKKQLQVKLEEEKTHLQEKL-RLQHEMELKARLTQAQASFEREREGLQ 746
Query: 175 ANL-----LQGVMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQIL 216
++ ++G+ LE FH+ Q+ L E+ + EL +++L
Sbjct: 747 SSAWTEEKVRGLTQELEQFHQ----EQLTSLVEKHTLEKEELRKELL 789
>gi|148536869 ninein isoform 2 [Homo sapiens]
Length = 2133
Score = 35.8 bits (81), Expect = 0.17
Identities = 38/167 (22%), Positives = 74/167 (44%), Gaps = 18/167 (10%)
Query: 63 EVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEKSE 122
E+ +K+R ++LD+ + + + Q N+ Q +K I L +I +++ +A +
Sbjct: 628 ELEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAVLK 687
Query: 123 QMVKEIT----RDIKQ----LDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTRRRQYGEV 174
+ E T + KQ L+ K HL + L H L + +A R + G
Sbjct: 688 EAHHEATCRHEEEKKQLQVKLEEEKTHLQEKL-RLQHEMELKARLTQAQASFEREREGLQ 746
Query: 175 ANL-----LQGVMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQIL 216
++ ++G+ LE FH+ Q+ L E+ + EL +++L
Sbjct: 747 SSAWTEEKVRGLTQELEQFHQ----EQLTSLVEKHTLEKEELRKELL 789
>gi|109134347 NY-REN-58 antigen [Homo sapiens]
Length = 701
Score = 35.8 bits (81), Expect = 0.17
Identities = 34/162 (20%), Positives = 77/162 (47%), Gaps = 21/162 (12%)
Query: 63 EVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEKSE 122
+V N R+++R+L + ++ VR Q E +K +Q + + +K K+E
Sbjct: 244 QVENAQRIQVRQLAE-MQATVRSLEAEKQSANLRAERLEKELQSSSEQNTFLINKLHKAE 302
Query: 123 QMVKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTR-RRQYGEVANLLQGV 181
+ + ++ +K+L H+ + T I +++ A + R+ ++ + L G+
Sbjct: 303 REINTLSSKVKELKHSNKLEITDIK-----------LETARAKSELERERNKIQSELDGL 351
Query: 182 MN-------VLEHFHKYMGIPQIRQLSERVKAAQTELGQQIL 216
+ +EH HK + + + R+L +V+AA+ E Q+++
Sbjct: 352 QSDNEILKAAVEH-HKVLLVEKDRELIRKVQAAKEEGYQKLV 392
>gi|109134355 NY-REN-58 antigen [Homo sapiens]
Length = 701
Score = 35.8 bits (81), Expect = 0.17
Identities = 34/162 (20%), Positives = 77/162 (47%), Gaps = 21/162 (12%)
Query: 63 EVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEKSE 122
+V N R+++R+L + ++ VR Q E +K +Q + + +K K+E
Sbjct: 244 QVENAQRIQVRQLAE-MQATVRSLEAEKQSANLRAERLEKELQSSSEQNTFLINKLHKAE 302
Query: 123 QMVKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTR-RRQYGEVANLLQGV 181
+ + ++ +K+L H+ + T I +++ A + R+ ++ + L G+
Sbjct: 303 REINTLSSKVKELKHSNKLEITDIK-----------LETARAKSELERERNKIQSELDGL 351
Query: 182 MN-------VLEHFHKYMGIPQIRQLSERVKAAQTELGQQIL 216
+ +EH HK + + + R+L +V+AA+ E Q+++
Sbjct: 352 QSDNEILKAAVEH-HKVLLVEKDRELIRKVQAAKEEGYQKLV 392
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 35.8 bits (81), Expect = 0.17
Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Query: 47 YINTLFPTEQSLANIDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQ 106
Y +F TE + + + V +++ N +RG T + LE+ +K I
Sbjct: 393 YKRNMFATESYIIDSAQAVQIKKMEPDEQLRNDHMNLRGHTPLDTQ----LEDKEKKISA 448
Query: 107 LFGKIKDIKDKAEKSEQMVKEITRDIKQLDHA 138
++ ++ D+ EK+EQ + T + KQL+ A
Sbjct: 449 AQTRLSELHDEIEKAEQQILRATEEFKQLEEA 480
Score = 30.4 bits (67), Expect = 7.1
Identities = 31/151 (20%), Positives = 61/151 (40%), Gaps = 11/151 (7%)
Query: 6 ELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLANIDEVV 65
ELE + L+ + E++ + + + L AD E + L T++ N E
Sbjct: 1404 ELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKF 1463
Query: 66 NKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEKSEQMV 125
+ + + + + + R Q+ L +A + ++ L KD++ K E+++
Sbjct: 1464 TDAKRSLLQTESDAEELERR----AQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEIL 1519
Query: 126 KEITR-------DIKQLDHAKRHLTTSITTL 149
KEI + D + L K LT + L
Sbjct: 1520 KEINKIVAAKDSDFQCLSKKKEKLTEELQKL 1550
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 35.4 bits (80), Expect = 0.22
Identities = 20/95 (21%), Positives = 50/95 (52%), Gaps = 7/95 (7%)
Query: 58 LANIDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDK 117
++ ++ V+ ++R +I DN++ + +N+ Q A + + A++ K+ D++D
Sbjct: 398 ISELNRVIQRLRSEI----DNVKKQI---SNLQQSISDAEQRGENALKDAKNKLNDLEDA 450
Query: 118 AEKSEQMVKEITRDIKQLDHAKRHLTTSITTLNHL 152
+++++ + + RD ++L + K L I T L
Sbjct: 451 LQQAKEDLARLLRDYQELMNTKLALDLEIATYRTL 485
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 35.4 bits (80), Expect = 0.22
Identities = 33/138 (23%), Positives = 64/138 (46%), Gaps = 14/138 (10%)
Query: 4 EEELEFVEELEAVL-QLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLANID 62
+E+L VE +L + E+++A+EQ ++ ++ +A + + L SL N
Sbjct: 1672 KEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTK 1731
Query: 63 EVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEKS- 121
++L+ +I N Q+ R A E+A+KAI +++K + + S
Sbjct: 1732 ----------KKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSA 1781
Query: 122 --EQMVKEITRDIKQLDH 137
E+M K + + +K L H
Sbjct: 1782 HLERMKKNLEQTVKDLQH 1799
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 35.4 bits (80), Expect = 0.22
Identities = 39/170 (22%), Positives = 76/170 (44%), Gaps = 14/170 (8%)
Query: 55 EQSLANIDEVVNKIRLKIRR----LDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGK 110
+Q+L E K R +RR L++ R + R + ++ + E++++A+QQL +
Sbjct: 816 QQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQ 875
Query: 111 IKDIKDKAEK----SEQMVKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMT 166
++D K+KA + +++ K+ + ++ L I L A E T
Sbjct: 876 LEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQ----ALQASQAERDT 931
Query: 167 RRRQYGEVANLLQGVMNVLEHFHKYMG--IPQIRQLSERVKAAQTELGQQ 214
R +A LQG+ E+ + Q++ L E+V +TEL ++
Sbjct: 932 ARLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETELDEE 981
>gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]
Length = 438
Score = 35.0 bits (79), Expect = 0.29
Identities = 37/172 (21%), Positives = 79/172 (45%), Gaps = 18/172 (10%)
Query: 2 MEEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLANI 61
++EE+ + E EA+L+ T AIE+ + + A+ + E +Q + +
Sbjct: 253 LQEEQRKHSAEKEALLEETNSFLKAIEE---ANKKMQAAEISLEE-------KDQRIGEL 302
Query: 62 DEVVNKIRLKIRRLDDNI---RTVVRGQ-TNVGQDGRQALEEAQKAIQQLFGKIKDIKDK 117
D ++ ++ + +L + T + G+ T+ ++ Q LEEA ++++ +I+ + D
Sbjct: 303 DRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRE---RIRHLDDM 359
Query: 118 AEKSEQMVKEITRDIKQLDHAKRHLT-TSITTLNHLHMLAGGVDSLEAMTRR 168
++ VK++ + +L +LT T T + G D L + T R
Sbjct: 360 VHCQQKKVKQMVEENNELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTGR 411
>gi|62821790 leucine zipper protein 2 [Homo sapiens]
Length = 346
Score = 35.0 bits (79), Expect = 0.29
Identities = 29/151 (19%), Positives = 70/151 (46%), Gaps = 10/151 (6%)
Query: 67 KIRLKIRRLDD-NIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEKSEQMV 125
K+ L+ + D+ + +T V+ +GQ R+ ++ Q+A+Q ++K+ +KAEK + +
Sbjct: 56 KVNLQSLKNDEQSAKTDVQKLLELGQKQREEMKSLQEALQ---NQLKETSEKAEKHQATI 112
Query: 126 KEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTRRRQYGEVANLLQGVMNVL 185
+ ++++ R L +L + + + + A ++ ++ L G ++L
Sbjct: 113 NFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLL 172
Query: 186 EHFHKYMGIPQIRQLSERVKAAQTELGQQIL 216
Q+ L +++ A+ EL + L
Sbjct: 173 ------FKAQQLTDLEQKLAVAKNELEKAAL 197
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 35.0 bits (79), Expect = 0.29
Identities = 56/296 (18%), Positives = 115/296 (38%), Gaps = 44/296 (14%)
Query: 12 ELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNA-VEYINTLFPTEQSLAN---------- 60
E EA ++ +PE + + F +Q L +A + + +N +++LA
Sbjct: 493 EQEAQVETSPETSRSSD-AFTTQHALRQAQMSKELVELNKALALKEALARKMTQNDSQLQ 551
Query: 61 -----IDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQAL--EEAQKAIQQLFGKIKD 113
+ + ++ L++ L +V +D QA E +K +Q+L G+I D
Sbjct: 552 PIQYQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRRKRLQELEGQIAD 611
Query: 114 IKDK----------AEKSEQMVKEITRDIKQLDHAKRHLTTSITT-----LNHLHMLAGG 158
+K K E +E+ V ++ ++I+ + + + L +
Sbjct: 612 LKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKE 671
Query: 159 VDSLEAMTRRRQYGEVANLLQGVMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQILAD 218
V L+ R+RQY ++ + +F K + +R+ +E AA L +
Sbjct: 672 VIQLKERDRKRQY--------ELLKLERNFQKQSNV--LRRKTEEAAAANKRLKDALQKQ 721
Query: 219 FEEAFPSQGTKRPGGPSNVLRDACLVANILDPRIKQEIIKKFIKQHLSEYLVLFQE 274
E A + T+ G R + N ++ + E K+ + L + +L Q+
Sbjct: 722 REVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQD 777
>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 [Homo
sapiens]
Length = 1288
Score = 35.0 bits (79), Expect = 0.29
Identities = 25/110 (22%), Positives = 56/110 (50%), Gaps = 5/110 (4%)
Query: 33 SQDPLDRADFNAVEYINTLFPTEQSLANIDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQD 92
+Q + AD N + +++ TE+ + + ++ V+ + +++ L+D VV+ TN +
Sbjct: 923 AQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTAELKSLEDKAAEVVK-NTNAAE- 980
Query: 93 GRQALEEAQKAIQQLFGKIKDIKDKAEKSEQMVKEITRDIKQLD-HAKRH 141
++L E QK + L ++K I++ ++ I ++Q+D H H
Sbjct: 981 --ESLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQIDGHIAEH 1028
Score = 31.6 bits (70), Expect = 3.2
Identities = 23/98 (23%), Positives = 49/98 (50%), Gaps = 3/98 (3%)
Query: 55 EQSLANIDEVVNKIRLKIRRLDDNIRTVV-RGQTNVGQ--DGRQALEEAQKAIQQLFGKI 111
E+ L + VN+ R K+ + + R T V Q ++AL A + +++ I
Sbjct: 482 EKELMGFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERKAAI 541
Query: 112 KDIKDKAEKSEQMVKEITRDIKQLDHAKRHLTTSITTL 149
+DI+ K ++EQ +KE +++++L + + + + L
Sbjct: 542 RDIEGKLPQTEQELKEKEKELQKLTQEETNFKSLVHDL 579
>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 [Homo
sapiens]
Length = 1288
Score = 35.0 bits (79), Expect = 0.29
Identities = 25/110 (22%), Positives = 56/110 (50%), Gaps = 5/110 (4%)
Query: 33 SQDPLDRADFNAVEYINTLFPTEQSLANIDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQD 92
+Q + AD N + +++ TE+ + + ++ V+ + +++ L+D VV+ TN +
Sbjct: 923 AQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTAELKSLEDKAAEVVK-NTNAAE- 980
Query: 93 GRQALEEAQKAIQQLFGKIKDIKDKAEKSEQMVKEITRDIKQLD-HAKRH 141
++L E QK + L ++K I++ ++ I ++Q+D H H
Sbjct: 981 --ESLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQIDGHIAEH 1028
Score = 31.6 bits (70), Expect = 3.2
Identities = 23/98 (23%), Positives = 49/98 (50%), Gaps = 3/98 (3%)
Query: 55 EQSLANIDEVVNKIRLKIRRLDDNIRTVV-RGQTNVGQ--DGRQALEEAQKAIQQLFGKI 111
E+ L + VN+ R K+ + + R T V Q ++AL A + +++ I
Sbjct: 482 EKELMGFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERKAAI 541
Query: 112 KDIKDKAEKSEQMVKEITRDIKQLDHAKRHLTTSITTL 149
+DI+ K ++EQ +KE +++++L + + + + L
Sbjct: 542 RDIEGKLPQTEQELKEKEKELQKLTQEETNFKSLVHDL 579
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 34.7 bits (78), Expect = 0.37
Identities = 67/342 (19%), Positives = 135/342 (39%), Gaps = 51/342 (14%)
Query: 12 ELEAVLQLTPEVQLAIEQVFPSQDPLDRADFN--AVEYINTLFPTEQSLANIDEVVNKIR 69
E EA ++ +PE + + F +Q L +A + VE N L E + + + N+++
Sbjct: 493 EEEAQVETSPETSRSSD-AFTTQHALHQAQMSKEVVELNNALALKEALVRKMTQNDNQLQ 551
Query: 70 LKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQ----------------KAIQQLFGKIKD 113
+ DNI+ + N+ ++ + + E Q K +Q+L G+I D
Sbjct: 552 PIQFQYQDNIKNLELEVINLQKEKEELVRELQTAKKNVNQAKLSEHRHKLLQELEGQIAD 611
Query: 114 IKDK----------AEKSEQMVKEITRDIKQLDHAKRHLTTSITT-----LNHLHMLAGG 158
+K K E +E+ V ++ ++I + + + L +
Sbjct: 612 LKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKE 671
Query: 159 VDSLEAMTRRRQYGEVANLLQGVMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQILAD 218
V L+ R+RQY ++ + +F K + +R+ +E AA L +
Sbjct: 672 VIQLKERDRKRQY--------ELLKLERNFQKQSSV--LRRKTEEAAAANKRLKDALQKQ 721
Query: 219 FEEAFPSQGTKRPGGPSNVLRDACLVANILDPRIKQEIIKKFIKQHLSEYLVLFQENQDV 278
E + T+ G R + N ++ + E K+ + L + +L QDV
Sbjct: 722 REVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKIL---AQDV 778
Query: 279 AWL-DKIDRRY---AWIKRQLVDYEEKYGRMFPREWCMAERI 316
L +K + R +++ E +G++ E C+ ++I
Sbjct: 779 VQLKEKKESRENPPPKLRKCTFSLSEVHGQVLESEDCITKQI 820
>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
Length = 284
Score = 34.3 bits (77), Expect = 0.49
Identities = 45/203 (22%), Positives = 92/203 (45%), Gaps = 18/203 (8%)
Query: 33 SQDPLDRADFNAVEYINTLFPTEQSLANIDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQD 92
++D LD+ + + L TE+ ++ + V + +I+ +++ + R Q +
Sbjct: 53 TEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELD---RAQERLAT- 108
Query: 93 GRQALEEAQKAIQQLFGKIKDIKDKAEKSEQMVKEITRDIKQLDHAKRHLTTSITTL-NH 151
Q LEEA+KA + +K I+++A K E+ ++ +K+ H +
Sbjct: 109 ALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARK 168
Query: 152 LHMLAGGVDSLE--AMTRRRQYGEVANLLQGVMNVLEHF----HKYMG-----IPQIRQL 200
L +L G ++ E A + G++ L+ V N L+ KY +I+ L
Sbjct: 169 LVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLL 228
Query: 201 SERVKAAQT--ELGQQILADFEE 221
S+++K A+T E ++ +A E+
Sbjct: 229 SDKLKEAETRAEFAERTVAKLEK 251
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 34.3 bits (77), Expect = 0.49
Identities = 33/140 (23%), Positives = 62/140 (44%), Gaps = 6/140 (4%)
Query: 3 EEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYI-NTLFPTEQSLANI 61
+E L+ E+ EA + + +E+ +++ L R + + + L E SL
Sbjct: 15 KENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAA 74
Query: 62 DEVVNKIRLKIRRLDDNIRTVV----RGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDK 117
+E K + L+ I+ V R Q + Q LEEA+KA + +K I+ +
Sbjct: 75 EEAAAKAEADVASLNRRIQLVEEELDRAQERLAT-ALQKLEEAEKAADESERGMKVIESR 133
Query: 118 AEKSEQMVKEITRDIKQLDH 137
A+K E+ ++ +K+ H
Sbjct: 134 AQKDEEKMEIQEIQLKEAKH 153
Score = 30.4 bits (67), Expect = 7.1
Identities = 23/105 (21%), Positives = 44/105 (41%), Gaps = 3/105 (2%)
Query: 40 ADFNAVEYINTLFPTEQSLANIDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGR---QA 96
AD E L E L +E K L++ ++TV ++ Q
Sbjct: 158 ADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQK 217
Query: 97 LEEAQKAIQQLFGKIKDIKDKAEKSEQMVKEITRDIKQLDHAKRH 141
+ ++ I+ L K+K+ + +AE +E+ V ++ + I L+ H
Sbjct: 218 EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAH 262
>gi|110349797 homer 2 isoform 4 [Homo sapiens]
Length = 299
Score = 34.3 bits (77), Expect = 0.49
Identities = 27/119 (22%), Positives = 54/119 (45%), Gaps = 10/119 (8%)
Query: 56 QSLANIDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIK 115
QS AN+ +N+ + K +L I + + + + L + + I QL + + +
Sbjct: 175 QSAANVKNEINREKEKNTQLKRRIEEL-EAELREKETELKDLRKQSEIIPQLMSECEYVS 233
Query: 116 DKAEKSEQ-------MVKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTR 167
+K E +E+ V+ + DI++ + +RHL + + L +L G +D L R
Sbjct: 234 EKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSF--LEVLDGKIDDLHDFRR 290
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,277,051
Number of Sequences: 37866
Number of extensions: 1347270
Number of successful extensions: 5881
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 106
Number of HSP's that attempted gapping in prelim test: 5667
Number of HSP's gapped (non-prelim): 351
length of query: 832
length of database: 18,247,518
effective HSP length: 111
effective length of query: 721
effective length of database: 14,044,392
effective search space: 10126006632
effective search space used: 10126006632
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.