Guide to the Human Genome
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Search of human proteins with 189491742

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189491742 ataxin 7 isoform b [Homo sapiens]
         (945 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189491742 ataxin 7 isoform b [Homo sapiens]                       1927   0.0  
gi|4506797 ataxin 7 isoform a [Homo sapiens]                         1810   0.0  
gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens]                 494   e-139
gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens]                 372   e-103
gi|93277115 ataxin 7-like 2 [Homo sapiens]                            263   4e-70
gi|23308753 ataxin 7-like 1 isoform 2 [Homo sapiens]                  120   5e-27
gi|150170670 piccolo isoform 2 [Homo sapiens]                          70   7e-12
gi|150378539 piccolo isoform 1 [Homo sapiens]                          70   7e-12
gi|161016767 mucin 21 [Homo sapiens]                                   61   6e-09
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         60   1e-08
gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo...    58   5e-08
gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo...    58   5e-08
gi|91982772 mucin 17 [Homo sapiens]                                    55   3e-07
gi|167736355 mucin 4 isoform a [Homo sapiens]                          55   4e-07
gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens]          55   4e-07
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        55   4e-07
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    54   7e-07
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  53   1e-06
gi|5174545 myocyte enhancer factor 2D [Homo sapiens]                   53   2e-06
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    52   3e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         52   3e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   51   4e-06
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   51   4e-06
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   51   4e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    51   4e-06
gi|153792074 proline rich 12 [Homo sapiens]                            51   4e-06
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        50   8e-06
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        50   8e-06
gi|126090663 zinc finger homeodomain 4 [Homo sapiens]                  50   8e-06
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       50   1e-05

>gi|189491742 ataxin 7 isoform b [Homo sapiens]
          Length = 945

 Score = 1927 bits (4992), Expect = 0.0
 Identities = 945/945 (100%), Positives = 945/945 (100%)

Query: 1   MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRP 60
           MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRP
Sbjct: 1   MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRP 60

Query: 61  EDGGPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFG 120
           EDGGPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFG
Sbjct: 61  EDGGPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFG 120

Query: 121 KNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPPLAV 180
           KNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPPLAV
Sbjct: 121 KNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPPLAV 180

Query: 181 PPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHP 240
           PPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHP
Sbjct: 181 PPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHP 240

Query: 241 IQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTL 300
           IQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTL
Sbjct: 241 IQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTL 300

Query: 301 PSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTR 360
           PSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTR
Sbjct: 301 PSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTR 360

Query: 361 SLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPR 420
           SLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPR
Sbjct: 361 SLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPR 420

Query: 421 TSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPP 480
           TSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPP
Sbjct: 421 TSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPP 480

Query: 481 LPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRW 540
           LPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRW
Sbjct: 481 LPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRW 540

Query: 541 NRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVS 600
           NRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVS
Sbjct: 541 NRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVS 600

Query: 601 TSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS 660
           TSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS
Sbjct: 601 TSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS 660

Query: 661 SVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSS 720
           SVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSS
Sbjct: 661 SVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSS 720

Query: 721 SSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPP 780
           SSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPP
Sbjct: 721 SSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPP 780

Query: 781 TGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCS 840
           TGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCS
Sbjct: 781 TGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCS 840

Query: 841 PSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQDISSPCLRTGISA 900
           PSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQDISSPCLRTGISA
Sbjct: 841 PSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQDISSPCLRTGISA 900

Query: 901 TSPQSPDLKSKGTSLTAENSTGRNNADTFEDKLHLHSALWTPRCL 945
           TSPQSPDLKSKGTSLTAENSTGRNNADTFEDKLHLHSALWTPRCL
Sbjct: 901 TSPQSPDLKSKGTSLTAENSTGRNNADTFEDKLHLHSALWTPRCL 945


>gi|4506797 ataxin 7 isoform a [Homo sapiens]
          Length = 892

 Score = 1810 bits (4688), Expect = 0.0
 Identities = 888/892 (99%), Positives = 889/892 (99%)

Query: 1   MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRP 60
           MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRP
Sbjct: 1   MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRP 60

Query: 61  EDGGPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFG 120
           EDGGPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFG
Sbjct: 61  EDGGPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFG 120

Query: 121 KNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPPLAV 180
           KNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPPLAV
Sbjct: 121 KNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPPLAV 180

Query: 181 PPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHP 240
           PPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHP
Sbjct: 181 PPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHP 240

Query: 241 IQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTL 300
           IQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTL
Sbjct: 241 IQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTL 300

Query: 301 PSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTR 360
           PSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTR
Sbjct: 301 PSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTR 360

Query: 361 SLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPR 420
           SLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPR
Sbjct: 361 SLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPR 420

Query: 421 TSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPP 480
           TSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPP
Sbjct: 421 TSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPP 480

Query: 481 LPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRW 540
           LPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRW
Sbjct: 481 LPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRW 540

Query: 541 NRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVS 600
           NRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVS
Sbjct: 541 NRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVS 600

Query: 601 TSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS 660
           TSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS
Sbjct: 601 TSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS 660

Query: 661 SVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSS 720
           SVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSS
Sbjct: 661 SVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSS 720

Query: 721 SSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPP 780
           SSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPP
Sbjct: 721 SSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPP 780

Query: 781 TGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCS 840
           TGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCS
Sbjct: 781 TGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCS 840

Query: 841 PSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQDISSP 892
           PSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQ  + P
Sbjct: 841 PSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQPKARP 892


>gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens]
          Length = 861

 Score =  494 bits (1272), Expect = e-139
 Identities = 357/903 (39%), Positives = 487/903 (53%), Gaps = 107/903 (11%)

Query: 64  GPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNR 123
           G G       AMAT+   R +PSPE  LG+ W+ W++A+KL   D  +L+E+ KE GK+R
Sbjct: 18  GTGKKQQEGRAMATLD--RKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSR 75

Query: 124 EVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKP-PLAVPP 182
           EVM L +EDM +FG  PAHDDFYLVVC+ CNQVVKPQ FQSH ERRH S  +P P  V P
Sbjct: 76  EVMRLNKEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCERRHGSMCRPSPSPVSP 135

Query: 183 TSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTR-PMHPI 241
            S  +   SL + K  +    + S        +SS+SK  K+PK+ L    + +  + P 
Sbjct: 136 AS--NPRTSLVQVKTKACLSGHHS--------ASSTSKPFKTPKDNLLTSSSKQHTVFPA 185

Query: 242 QQSRVPHGRIMTPSVKVEKIH--PKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPT 299
           + SR     +  P V +EKI    K DG  +K     T   + SS     ++ P + KP 
Sbjct: 186 KGSR-DKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPV 244

Query: 300 L------PSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLD 353
           L      PSP +ILNGKG+  P T++KK ++ + N     +RLSEREFDP+ HCGV+D +
Sbjct: 245 LMSKSVPPSPEKILNGKGI-LPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPE 303

Query: 354 TKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRD 413
           TKKPCTRSLTCKTHSL+ RRAV GR+K+FD+LLAEHK K+REKE+    D +      R+
Sbjct: 304 TKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEV---KDKEHLLTSTRE 360

Query: 414 PHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPV 473
             P+    +Q+      G    E K    +K +P    LPRP    A    S+       
Sbjct: 361 ILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSS--ANSISSSTSSNHSG 418

Query: 474 HESPHPPLPAT--EPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGR 531
           H +P PPLP    + ASRLSS+EGE D  +ES EKLDC +S HHP+P +FC+FGSR +GR
Sbjct: 419 H-TPEPPLPPVGGDLASRLSSDEGEMDGADES-EKLDCQFSTHHPRPLAFCSFGSRLMGR 476

Query: 532 GYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIP-----PVPSTTSPISTRIPHRTNSVPT 586
           GYYVFD RW+R R ALN MVEKHLN+Q+WKKIP     P+PS  + I+T +P      P 
Sbjct: 477 GYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPASVLQ-PF 535

Query: 587 SQCGVSYLAAATVS---TSPVLLSSTCI-------SPNSKSVPAHGTTLNAQPAASGAMD 636
           S     YL +A +S   TS  +++S  +       SP+  ++ +H T      A    MD
Sbjct: 536 SNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMD 595

Query: 637 PVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNAS 696
                      S+  +PS  S + +V  SP S KP K K+SKS + K+ S         +
Sbjct: 596 -----------STFKAPSAVSPIPAVIPSP-SHKPSKTKTSKSSKVKDLS---------T 634

Query: 697 SSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMES-----FRKNCVAH---------S 742
            S    S KKRK  S     SSSSSSSSSS   S+ S      +KNCV +         +
Sbjct: 635 RSDESPSNKKRKPQSST---SSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQA 691

Query: 743 GPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDS-T 801
            PPY       +S+ ++   N  + ++ + + SGR    G PA+ ++++  +  SSDS  
Sbjct: 692 APPY-------NSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCP 744

Query: 802 LSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPA 861
           LS+      + +L + SH + S      DK  GKKRK S       +SSSK  K+ K+P 
Sbjct: 745 LSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNS-------SSSSKACKITKMPG 797

Query: 862 VNNVHMKH-TGTIPGAQGLMNSSLLHQDISSPCLRTGISATSPQSPDLKSKGTSLTAENS 920
           +N+VH K+    +      +NS+   Q   +  L   +S +SP S  + S G S    N 
Sbjct: 798 MNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSL--ALSQSSPSS--ISSPGHSRQNTNR 853

Query: 921 TGR 923
           TGR
Sbjct: 854 TGR 856


>gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens]
          Length = 738

 Score =  372 bits (956), Expect = e-103
 Identities = 285/753 (37%), Positives = 397/753 (52%), Gaps = 95/753 (12%)

Query: 214 ASSSSSKLLKSPKEKLQLRGNTR-PMHPIQQSRVPHGRIMTPSVKVEKIHP--KMDGTLL 270
           ++SS+SK  K+PK+ L    + +  + P + SR     +  P V +EKI    K DG  +
Sbjct: 33  SASSTSKPFKTPKDNLLTSSSKQHTVFPAKGSR-DKPCVPVPVVSLEKIPNLVKADGANV 91

Query: 271 KSAVGPTCPATVSSLVKPGLNCPSIPKPTL------PSPGQILNGKGLPAPPTLEKKPED 324
           K     T   + SS     ++ P + KP L      PSP +ILNGKG+  P T++KK ++
Sbjct: 92  KMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSKSVPPSPEKILNGKGI-LPTTIDKKHQN 150

Query: 325 NSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDV 384
            + N     +RLSEREFDP+ HCGV+D +TKKPCTRSLTCKTHSL+ RRAV GR+K+FD+
Sbjct: 151 GTKNSNKPYRRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDL 210

Query: 385 LLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASK 444
           LLAEHK K+REKE+    D +      R+  P+    +Q+      G    E K    +K
Sbjct: 211 LLAEHKAKSREKEV---KDKEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAK 267

Query: 445 PKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPAT--EPASRLSSEEGEGDDKEE 502
            +P    LPRP    A    S+       H +P PPLP    + ASRLSS+EGE D  +E
Sbjct: 268 SRPPNSVLPRPSS--ANSISSSTSSNHSGH-TPEPPLPPVGGDLASRLSSDEGEMDGADE 324

Query: 503 SVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKK 562
           S EKLDC +S HHP+P +FC+FGSR +GRGYYVFD RW+R R ALN MVEKHLN+Q+WKK
Sbjct: 325 S-EKLDCQFSTHHPRPLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKK 383

Query: 563 IP-----PVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVS---TSPVLLSSTCI--- 611
           IP     P+PS  + I+T +P      P S     YL +A +S   TS  +++S  +   
Sbjct: 384 IPPAADSPLPSPAAHITTPVPASVLQ-PFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNA 442

Query: 612 ----SPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPM 667
               SP+  ++ +H T      A    MD           S+  +PS  S + +V  SP 
Sbjct: 443 AFVTSPDPSALMSHTTAFPHVAATLSIMD-----------STFKAPSAVSPIPAVIPSP- 490

Query: 668 SRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSS 727
           S KP K K+SKS + K+ S         + S    S KKRK  S     SSSSSSSSSS 
Sbjct: 491 SHKPSKTKTSKSSKVKDLS---------TRSDESPSNKKRKPQSST---SSSSSSSSSSL 538

Query: 728 SHSMES-----FRKNCVAH---------SGPPYPSTVTSSHSIGLNCVTNKANAVNVRHD 773
             S+ S      +KNCV +         + PPY       +S+ ++   N  + ++ + +
Sbjct: 539 QTSLSSPLSGPHKKNCVLNASSALNSYQAAPPY-------NSLSVHNSNNGVSPLSAKLE 591

Query: 774 QSGRGPPTGSPAESIKRMSVMVNSSDS-TLSLGPFIHQSNELPVNSHGSFSHSHTPLDKL 832
            SGR    G PA+ ++++  +  SSDS  LS+      + +L + SH + S      DK 
Sbjct: 592 PSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKS 651

Query: 833 IGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKH-TGTIPGAQGLMNSSLLHQDISS 891
            GKKRK S       +SSSK  K+ K+P +N+VH K+    +      +NS+   Q   +
Sbjct: 652 EGKKRKNS-------SSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKN 704

Query: 892 PCLRTGISATSPQSPDLKSKGTSLTAE-NSTGR 923
             L   +S +SP S  + S G S     N TGR
Sbjct: 705 SSL--ALSQSSPSS--ISSPGHSRQKNTNRTGR 733


>gi|93277115 ataxin 7-like 2 [Homo sapiens]
          Length = 722

 Score =  263 bits (673), Expect = 4e-70
 Identities = 237/753 (31%), Positives = 324/753 (43%), Gaps = 116/753 (15%)

Query: 71  SAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNREVMGLCR 130
           +AAAMA + ERR +PS +   GQSW+ WVE + LP  DG EL+ES K   K  + M L +
Sbjct: 7   AAAAMAAL-ERR-VPSLDDFAGQSWSSWVERADLPAADGAELEESSKNT-KKLDAMTLIK 63

Query: 131 EDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSK-----PPLAVPPTSV 185
           EDM IFG CPAHDDFYLVVCN C+QVVKPQAFQ H ERRH   SK     PP    P S 
Sbjct: 64  EDMSIFGHCPAHDDFYLVVCNHCSQVVKPQAFQKHCERRHGPLSKLYGRAPPPPPAPASS 123

Query: 186 FSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSR 245
                   +     A GS ++SS                 +EK Q  G+    H      
Sbjct: 124 QKCHVVNGQGPACRAPGSTKTSS-----------------REKGQ--GSRSRGHQ----- 159

Query: 246 VPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTLPSPGQ 305
                   P  K +K +    G L K + G   P    S   PG     I    +PS G 
Sbjct: 160 --------PPEKTQKDNLCQPGGLTKDSPGKP-PMAPPSKEPPGRENIEI----IPSEGS 206

Query: 306 ILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCK 365
               +G P     EK+P       K  +++++ +E D +  CGVI+ +TKK CTR LTCK
Sbjct: 207 SHWAEGSPP----EKEPSGTRLPPK-THRKMARKECDLNRQCGVINPETKKICTRLLTCK 261

Query: 366 THSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQ-- 423
            HS+ QRR VQGR K FDVL+AE K  +R+ E  +     +  Q L  P    P + Q  
Sbjct: 262 IHSVHQRREVQGRAKDFDVLVAELKANSRKGESPKEKSPGRKEQVLERPSQELPSSVQVV 321

Query: 424 ---EPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPP 480
                  +   V   ++ P+ A      +         P    G   + P P+      P
Sbjct: 322 AAVAAPSSTFSVRAKQTYPYCALPRSRASSESELDDEGPCGGDGDPGLFPFPM------P 375

Query: 481 LPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRW 540
              T+ +S  S EEG  DD        DCHY+   P+P +FCTFGSR +  G YVF  R 
Sbjct: 376 RGGTQASSEESEEEGTSDDLHPPP---DCHYATRPPRPQAFCTFGSRLVSPGCYVFSRRL 432

Query: 541 NRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVS 600
           +R   AL+ M+E+HL+  +WKKIPP     +       H  NS P S    + L+ ++  
Sbjct: 433 DRFCSALSSMLERHLSTHMWKKIPPAAEPPA-------HLVNS-PLS----APLSPSSTG 480

Query: 601 TSPVLLSSTCISPNSKSV-PAHGTTLNAQPAASGAMDPVCS----MQSRQVSSSSSSPST 655
           T P L   T       S+ P     + + PA S ++   CS    M   Q  +S    +T
Sbjct: 481 TCPRLPGPTLRPACPASMPPTKDNLVPSYPAGSPSVAAACSQAECMGGSQAITSPLPANT 540

Query: 656 PS-GLSSVPSSPMSRK---------------------PQKLKSSKSLRPKESSGNSTNCQ 693
           PS   S +P S  S+                      P  LK +  L P    G  + C+
Sbjct: 541 PSPSFSKLPPSKASKSSKGKDGVEVEAPSRKRKLSPGPTTLKRTCILEP-TGKGKPSGCR 599

Query: 694 NASSST--------SGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPP 745
             S+ T        +G  G + K + PL    S     +   +  +E+  +    H    
Sbjct: 600 GLSAKTKTALSMGLNGTMGPRVKRAGPLDCRGSPHQLPTPVKASQLEN--RGAAGHPAKA 657

Query: 746 YPSTVTSSHSIG--LNCVTNKANAVNVRHDQSG 776
            P+   S   +      +      V  +H Q+G
Sbjct: 658 LPTNCLSEEEVAKKRKNLATYCRPVKAKHCQAG 690


>gi|23308753 ataxin 7-like 1 isoform 2 [Homo sapiens]
          Length = 146

 Score =  120 bits (302), Expect = 5e-27
 Identities = 59/109 (54%), Positives = 75/109 (68%), Gaps = 2/109 (1%)

Query: 64  GPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNR 123
           G G       AMAT+   R +PSPE  LG+ W+ W++A+KL   D  +L+E+ KE GK+R
Sbjct: 18  GTGKKQQEGRAMATLD--RKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSR 75

Query: 124 EVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSS 172
           EVM L +EDM +FG  PAHDDFYLVVC+ CNQVVKPQ FQSH  R+  +
Sbjct: 76  EVMRLNKEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCGRKQDN 124


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 70.5 bits (171), Expect = 7e-12
 Identities = 172/817 (21%), Positives = 258/817 (31%), Gaps = 121/817 (14%)

Query: 1   MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRP 60
           +SE     +     RA     G+   AA +     ++Q+     P +Q   PP P R   
Sbjct: 48  LSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQ 107

Query: 61  EDGGPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEF- 119
               PG + +         ++ P  SP  +           S    K  T+L E  K   
Sbjct: 108 ----PGLSKSRTTDTFRSEQKLPGRSPSTI-----------SLKESKSRTDLKEEHKSSM 152

Query: 120 --GKNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQ--VVKPQAFQSHYERRHSSSSK 175
             G   EV  L      +  F P    F L+  ++ +Q    K Q      + +     K
Sbjct: 153 MPGFLSEVNALSAVSSVVNKFNP----FDLISDSEASQEETTKKQKVVQKEQGKPEGIIK 208

Query: 176 PPLAVPPTSVFSFFPSLSKS---KGGSASGSNRSSSGGVLSASSSSSKLLKSPKE----- 227
           PPL   P           +    + G+    +      + S    + K ++ P +     
Sbjct: 209 PPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTD 268

Query: 228 --KLQL-RGNTRPMHPIQQSRVPHGRIMTPSVKVEKIHPKMDGTL----------LKSAV 274
             KL L R  +RP    +Q+ +  G  + PS+      P    T            KS  
Sbjct: 269 HAKLPLQRDASRPQ--TKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326

Query: 275 GPTCP-ATVSSLVKPGLNCPSIPKPTLPSPG------QILNGKGLPAPPTLEKKPEDNSN 327
           GP  P A  S L KP    P   KP +  PG      Q L     PA  T  +KP     
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP 386

Query: 328 NRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRF----- 382
             K L +     +  P    G     T++  T     +   L       G  K       
Sbjct: 387 GPKALAQPPGVGK-TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPG 445

Query: 383 -----------DVLLAEHKNKTREKELIRHPDSQQPPQP-LRDPHPAPPRTSQEPHQNPH 430
                          A+    T+    +  P    P QP    P P  P +++ P Q P 
Sbjct: 446 PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505

Query: 431 GVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRL 490
              P   +P  A KP P  P   +P   P+QQ GSA     P  + P P  P+ + +++ 
Sbjct: 506 STKPPPQQPGPA-KPSPQQPGSTKP---PSQQPGSA----KPSAQQPSPAKPSAQQSTKP 557

Query: 491 SSEEGEG-------------DDKEESVEKLDCHYSG------HHPQPASFCTFGSRQI-- 529
            S+ G G                 + + K  C          H P+ A+F T    Q   
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTV 617

Query: 530 -------GRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTN 582
                     +      W  L C         +   L   + PVPS+  P     P  T 
Sbjct: 618 CSLCGFNPNPHLTEVKEWLCLNC--------QMKRALGGDLAPVPSSPQPKLKTAPVTTT 669

Query: 583 SVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQ 642
           S  +         +     +P    S    P          TL+  P+A     P     
Sbjct: 670 SAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSL 729

Query: 643 SRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGG 702
           S+   +    PS PS     P +    KP++ K  K      SS ++T   +  SS    
Sbjct: 730 SK--PAPPKEPSVPSEQDKAPVA--DDKPKQPKMVKPTTDLVSSSSATTKPDIPSS-KVQ 784

Query: 703 SGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCV 739
           S  + K + PL   S+  S S   +   +  F    +
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAI 821



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 89/415 (21%), Positives = 145/415 (34%), Gaps = 70/415 (16%)

Query: 212  LSASSSSSKLLKSPKEKLQLRGNTRPMHPIQ-------QSRVPHGRIMTPSVKVEKIHPK 264
            L +SSS++     P  K+Q +   +   P++       QS  P G  ++P        P 
Sbjct: 766  LVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPA 825

Query: 265  MDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTL----PSPGQILNGKGLPAPP---- 316
             D  ++ S  GP+  +     V P +     PK       P P      KG P PP    
Sbjct: 826  SDSKII-SHPGPSSESKGQKQVDP-VQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883

Query: 317  -------TLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSL 369
                   T ++ P+    +R+F             ++ G I   T  P       K+   
Sbjct: 884  TAGQTVPTPQQSPKPQEQSRRF------------SLNLGSI---TDAP-------KSQPT 921

Query: 370  TQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPP-QPLRD-PHPAPPRTSQEPHQ 427
            T +  V G+   F   +    +          P SQ  P  P++  P P+ P TSQ P +
Sbjct: 922  TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPK 981

Query: 428  NPHGVIPSESK--PFVASKPKPHTPSL-PRPPGCPAQQGGSAPIDPPPVHESPHPPLPAT 484
            +     P+ +K  P       P    L P+    P  +       PPP+ +S        
Sbjct: 982  STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKS---LTA 1038

Query: 485  EPASRLSSEEGEGDDKEES---VEKLDCHYSGHHPQPASFCTFGSRQI-------GRGYY 534
            EP   +   + E   K ES   + K + +     P   + CT    Q+          + 
Sbjct: 1039 EPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHL 1098

Query: 535  VFDSRWNRLRCALNLMVEKHLNAQLW--KKIPPVPSTTSPISTRIPHRTNSVPTS 587
                 W      LN   ++ ++ QL   +K+PP PS        +P  ++S  T+
Sbjct: 1099 TEIQEW----LCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTA 1149



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 71/325 (21%), Positives = 121/325 (37%), Gaps = 58/325 (17%)

Query: 564  PPVPSTTSPISTRIPHR--TNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAH 621
            PP+P  TSP  T +P +  T + P +     + A  T+ T+ VL         S  +P  
Sbjct: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVL--------RSNGLPVT 2476

Query: 622  GTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLR 681
                 A P          S+ S  V +    PS P      P   + + P   +    + 
Sbjct: 2477 RICTTAPPPVP---PKPSSIPSGLVFTHRPEPSKP---PIAPKPVIPQLPTTTQKPTDIH 2530

Query: 682  PKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAH 741
            PK +  + T+    +  TS    K    +SPL  HS+ SS   S      +S  +  V  
Sbjct: 2531 PKPTGLSLTSSMTLNLVTS-ADYKLPSPTSPLSPHSNKSSPRFS------KSLTETYVVI 2583

Query: 742  SGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVN----- 796
            + P  P T T S +                  Q+    P GSP++ +  +  + +     
Sbjct: 2584 TLPSEPGTPTDSSA-----------------SQAITSWPLGSPSKDLVSVEPVFSVVPPV 2626

Query: 797  -------SSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIG---KKRKCSPSSS-- 844
                   SS+ T  +   +   +  PV +  SF  + T + + +     K + S + S  
Sbjct: 2627 TAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTA 2686

Query: 845  -SINNSSSKPTKVAKVPAVNNVHMK 868
             S+  SS   T   +  A++N+H++
Sbjct: 2687 PSVGLSSISITIPPEPLALDNIHLE 2711



 Score = 34.3 bits (77), Expect = 0.56
 Identities = 30/119 (25%), Positives = 43/119 (36%), Gaps = 12/119 (10%)

Query: 385  LLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPH-------QNPHGV----- 432
            L AE    +  + +  HP S     P+++       TS E         Q P G      
Sbjct: 2326 LEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSS 2385

Query: 433  IPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRLS 491
            +P++ +PF  S     +   P PP  P       P  PPP    P  P P   P  +L+
Sbjct: 2386 LPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT 2444



 Score = 33.9 bits (76), Expect = 0.74
 Identities = 64/297 (21%), Positives = 100/297 (33%), Gaps = 70/297 (23%)

Query: 402  PDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTP----------- 450
            P    PP P   P P PP     P  +P   I  + K  VAS     TP           
Sbjct: 2406 PPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETT 2465

Query: 451  SLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCH 510
            ++ R  G P  +       PPPV     PP P++ P+  + +   E      + + +   
Sbjct: 2466 AVLRSNGLPVTR--ICTTAPPPV-----PPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQ 2518

Query: 511  Y-------SGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKI 563
                    +  HP+P       S                    LNL+             
Sbjct: 2519 LPTTTQKPTDIHPKPTGLSLTSS------------------MTLNLVTSADYK------- 2553

Query: 564  PPVPSTTSPISTRIPHRTNSVPTSQCGV----------SYLAAATVSTSPVLLSSTCISP 613
              +PS TSP+S   PH   S P     +          S     T S++   ++S  +  
Sbjct: 2554 --LPSPTSPLS---PHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGS 2608

Query: 614  NSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSS----SSSPST-PSGLSSVPSS 665
             SK + +     +  P  +    P+ S Q+  +S +    S++P T PS   + P+S
Sbjct: 2609 PSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTS 2665



 Score = 30.4 bits (67), Expect = 8.1
 Identities = 13/30 (43%), Positives = 13/30 (43%)

Query: 36   QQQQPPPPQPQRQQHPPPPPRRTRPEDGGP 65
            Q   PPPP P     PPPPP    P    P
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 70.5 bits (171), Expect = 7e-12
 Identities = 172/817 (21%), Positives = 258/817 (31%), Gaps = 121/817 (14%)

Query: 1   MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRP 60
           +SE     +     RA     G+   AA +     ++Q+     P +Q   PP P R   
Sbjct: 48  LSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQ 107

Query: 61  EDGGPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEF- 119
               PG + +         ++ P  SP  +           S    K  T+L E  K   
Sbjct: 108 ----PGLSKSRTTDTFRSEQKLPGRSPSTI-----------SLKESKSRTDLKEEHKSSM 152

Query: 120 --GKNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQ--VVKPQAFQSHYERRHSSSSK 175
             G   EV  L      +  F P    F L+  ++ +Q    K Q      + +     K
Sbjct: 153 MPGFLSEVNALSAVSSVVNKFNP----FDLISDSEASQEETTKKQKVVQKEQGKPEGIIK 208

Query: 176 PPLAVPPTSVFSFFPSLSKS---KGGSASGSNRSSSGGVLSASSSSSKLLKSPKE----- 227
           PPL   P           +    + G+    +      + S    + K ++ P +     
Sbjct: 209 PPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTD 268

Query: 228 --KLQL-RGNTRPMHPIQQSRVPHGRIMTPSVKVEKIHPKMDGTL----------LKSAV 274
             KL L R  +RP    +Q+ +  G  + PS+      P    T            KS  
Sbjct: 269 HAKLPLQRDASRPQ--TKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326

Query: 275 GPTCP-ATVSSLVKPGLNCPSIPKPTLPSPG------QILNGKGLPAPPTLEKKPEDNSN 327
           GP  P A  S L KP    P   KP +  PG      Q L     PA  T  +KP     
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP 386

Query: 328 NRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRF----- 382
             K L +     +  P    G     T++  T     +   L       G  K       
Sbjct: 387 GPKALAQPPGVGK-TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPG 445

Query: 383 -----------DVLLAEHKNKTREKELIRHPDSQQPPQP-LRDPHPAPPRTSQEPHQNPH 430
                          A+    T+    +  P    P QP    P P  P +++ P Q P 
Sbjct: 446 PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505

Query: 431 GVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRL 490
              P   +P  A KP P  P   +P   P+QQ GSA     P  + P P  P+ + +++ 
Sbjct: 506 STKPPPQQPGPA-KPSPQQPGSTKP---PSQQPGSA----KPSAQQPSPAKPSAQQSTKP 557

Query: 491 SSEEGEG-------------DDKEESVEKLDCHYSG------HHPQPASFCTFGSRQI-- 529
            S+ G G                 + + K  C          H P+ A+F T    Q   
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTV 617

Query: 530 -------GRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTN 582
                     +      W  L C         +   L   + PVPS+  P     P  T 
Sbjct: 618 CSLCGFNPNPHLTEVKEWLCLNC--------QMKRALGGDLAPVPSSPQPKLKTAPVTTT 669

Query: 583 SVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQ 642
           S  +         +     +P    S    P          TL+  P+A     P     
Sbjct: 670 SAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSL 729

Query: 643 SRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGG 702
           S+   +    PS PS     P +    KP++ K  K      SS ++T   +  SS    
Sbjct: 730 SK--PAPPKEPSVPSEQDKAPVA--DDKPKQPKMVKPTTDLVSSSSATTKPDIPSS-KVQ 784

Query: 703 SGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCV 739
           S  + K + PL   S+  S S   +   +  F    +
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAI 821



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 89/415 (21%), Positives = 145/415 (34%), Gaps = 70/415 (16%)

Query: 212  LSASSSSSKLLKSPKEKLQLRGNTRPMHPIQ-------QSRVPHGRIMTPSVKVEKIHPK 264
            L +SSS++     P  K+Q +   +   P++       QS  P G  ++P        P 
Sbjct: 766  LVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPA 825

Query: 265  MDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTL----PSPGQILNGKGLPAPP---- 316
             D  ++ S  GP+  +     V P +     PK       P P      KG P PP    
Sbjct: 826  SDSKII-SHPGPSSESKGQKQVDP-VQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883

Query: 317  -------TLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSL 369
                   T ++ P+    +R+F             ++ G I   T  P       K+   
Sbjct: 884  TAGQTVPTPQQSPKPQEQSRRF------------SLNLGSI---TDAP-------KSQPT 921

Query: 370  TQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPP-QPLRD-PHPAPPRTSQEPHQ 427
            T +  V G+   F   +    +          P SQ  P  P++  P P+ P TSQ P +
Sbjct: 922  TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPK 981

Query: 428  NPHGVIPSESK--PFVASKPKPHTPSL-PRPPGCPAQQGGSAPIDPPPVHESPHPPLPAT 484
            +     P+ +K  P       P    L P+    P  +       PPP+ +S        
Sbjct: 982  STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKS---LTA 1038

Query: 485  EPASRLSSEEGEGDDKEES---VEKLDCHYSGHHPQPASFCTFGSRQI-------GRGYY 534
            EP   +   + E   K ES   + K + +     P   + CT    Q+          + 
Sbjct: 1039 EPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHL 1098

Query: 535  VFDSRWNRLRCALNLMVEKHLNAQLW--KKIPPVPSTTSPISTRIPHRTNSVPTS 587
                 W      LN   ++ ++ QL   +K+PP PS        +P  ++S  T+
Sbjct: 1099 TEIQEW----LCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTA 1149



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 71/325 (21%), Positives = 121/325 (37%), Gaps = 58/325 (17%)

Query: 564  PPVPSTTSPISTRIPHR--TNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAH 621
            PP+P  TSP  T +P +  T + P +     + A  T+ T+ VL         S  +P  
Sbjct: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVL--------RSNGLPVT 2476

Query: 622  GTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLR 681
                 A P          S+ S  V +    PS P      P   + + P   +    + 
Sbjct: 2477 RICTTAPPPVP---PKPSSIPSGLVFTHRPEPSKP---PIAPKPVIPQLPTTTQKPTDIH 2530

Query: 682  PKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAH 741
            PK +  + T+    +  TS    K    +SPL  HS+ SS   S      +S  +  V  
Sbjct: 2531 PKPTGLSLTSSMTLNLVTS-ADYKLPSPTSPLSPHSNKSSPRFS------KSLTETYVVI 2583

Query: 742  SGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVN----- 796
            + P  P T T S +                  Q+    P GSP++ +  +  + +     
Sbjct: 2584 TLPSEPGTPTDSSA-----------------SQAITSWPLGSPSKDLVSVEPVFSVVPPV 2626

Query: 797  -------SSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIG---KKRKCSPSSS-- 844
                   SS+ T  +   +   +  PV +  SF  + T + + +     K + S + S  
Sbjct: 2627 TAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTA 2686

Query: 845  -SINNSSSKPTKVAKVPAVNNVHMK 868
             S+  SS   T   +  A++N+H++
Sbjct: 2687 PSVGLSSISITIPPEPLALDNIHLE 2711



 Score = 34.3 bits (77), Expect = 0.56
 Identities = 30/119 (25%), Positives = 43/119 (36%), Gaps = 12/119 (10%)

Query: 385  LLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPH-------QNPHGV----- 432
            L AE    +  + +  HP S     P+++       TS E         Q P G      
Sbjct: 2326 LEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSS 2385

Query: 433  IPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRLS 491
            +P++ +PF  S     +   P PP  P       P  PPP    P  P P   P  +L+
Sbjct: 2386 LPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT 2444



 Score = 33.9 bits (76), Expect = 0.74
 Identities = 64/297 (21%), Positives = 100/297 (33%), Gaps = 70/297 (23%)

Query: 402  PDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTP----------- 450
            P    PP P   P P PP     P  +P   I  + K  VAS     TP           
Sbjct: 2406 PPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETT 2465

Query: 451  SLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCH 510
            ++ R  G P  +       PPPV     PP P++ P+  + +   E      + + +   
Sbjct: 2466 AVLRSNGLPVTR--ICTTAPPPV-----PPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQ 2518

Query: 511  Y-------SGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKI 563
                    +  HP+P       S                    LNL+             
Sbjct: 2519 LPTTTQKPTDIHPKPTGLSLTSS------------------MTLNLVTSADYK------- 2553

Query: 564  PPVPSTTSPISTRIPHRTNSVPTSQCGV----------SYLAAATVSTSPVLLSSTCISP 613
              +PS TSP+S   PH   S P     +          S     T S++   ++S  +  
Sbjct: 2554 --LPSPTSPLS---PHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGS 2608

Query: 614  NSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSS----SSSPST-PSGLSSVPSS 665
             SK + +     +  P  +    P+ S Q+  +S +    S++P T PS   + P+S
Sbjct: 2609 PSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTS 2665



 Score = 30.4 bits (67), Expect = 8.1
 Identities = 13/30 (43%), Positives = 13/30 (43%)

Query: 36   QQQQPPPPQPQRQQHPPPPPRRTRPEDGGP 65
            Q   PPPP P     PPPPP    P    P
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 84/365 (23%), Positives = 151/365 (41%), Gaps = 40/365 (10%)

Query: 568 STTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNA 627
           STTS  ++   +  +S P+S    +  + ++ ++S    ++   S  + S  +  T   +
Sbjct: 111 STTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSES 170

Query: 628 QPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSS------KSLR 681
              +SGA     S  S   S +S++ ++ S  +S  +S  +    +  S+       S  
Sbjct: 171 STTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSES 230

Query: 682 PKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAH 741
              SSG ST   + SS+ S G+G    + S      S++SS + ++++S  S   + +  
Sbjct: 231 STTSSGASTATNSESSTPSSGAGTATNSES------STTSSGAGTATNSESSTVSSGI-- 282

Query: 742 SGPPYPSTVTSSH----SIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKR-MSVMVN 796
                 STVT+S     S G N  TN  ++       SG    T S + +     S   N
Sbjct: 283 ------STVTNSESSTPSSGANTATNSESSTT----SSGANTATNSDSSTTSSGASTATN 332

Query: 797 SSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKV 856
           S  ST S G     ++E    S G+ + +++      G     S +S++ N+ SS  +  
Sbjct: 333 SESSTTSSGASTATNSESSTTSSGASTATNS------GSSTTSSGTSTATNSESSTVSSG 386

Query: 857 AKVPAVNNVHMKHTGTIPGAQGLMNS-SLLHQDISSPCLRTGISATSPQSPDLKSKGTSL 915
           A     +    + + T  GA    NS S      +S    +  S TS  +    + G+S+
Sbjct: 387 ASTATTS----ESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSV 442

Query: 916 TAENS 920
           T+  S
Sbjct: 443 TSAGS 447



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 78/320 (24%), Positives = 135/320 (42%), Gaps = 35/320 (10%)

Query: 614 NSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPS--TPSGLSSVPSSPMSRKP 671
           N  S  A+  +      AS A +   S+ S  VS+++ S S  T +G+S V +S      
Sbjct: 25  NETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTS 84

Query: 672 QKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSM 731
             + ++ +      S   +   N+ SST+        NS       SS+ SS +S++ + 
Sbjct: 85  SGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNS------ESSTPSSGASTATNS 138

Query: 732 ESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESI-KR 790
           +S   +  A +     S+ TSS +   +  TN  ++       SG    T S + ++  R
Sbjct: 139 DSSTTSSGASTATNSDSSTTSSEA---STATNSESSTT----SSGASTATNSESSTVSSR 191

Query: 791 MSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSS 850
            S   NS  ST S G     ++E    S+G+ + +++            S +S++ N+ S
Sbjct: 192 ASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSE------SSTTSSGASTATNSES 245

Query: 851 SKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQDISSPCLRTGISATSPQSPDLKS 910
           S P+  A   A N+   + + T  GA    NS        S  + +GIS  +       S
Sbjct: 246 STPSSGAGT-ATNS---ESSTTSSGAGTATNS-------ESSTVSSGISTVTNSESSTPS 294

Query: 911 KG--TSLTAENSTGRNNADT 928
            G  T+  +E+ST  + A+T
Sbjct: 295 SGANTATNSESSTTSSGANT 314



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 40/164 (24%), Positives = 71/164 (43%), Gaps = 9/164 (5%)

Query: 568 STTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNA 627
           STTS  ++   +  +S  +S    +  + ++ ++S    ++   S  + S  +  T   +
Sbjct: 321 STTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSES 380

Query: 628 QPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSG 687
              +SGA     S  S   +SS +S +T S  S+V S   +       ++ S     SSG
Sbjct: 381 STVSSGASTATTSESS--TTSSGASTATNSESSTVSSGAST-------ATNSESSTTSSG 431

Query: 688 NSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSM 731
            +T   + SS TS GSG           HS+S++ S +    S+
Sbjct: 432 ANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKPGGSL 475



 Score = 33.9 bits (76), Expect = 0.74
 Identities = 42/178 (23%), Positives = 73/178 (41%), Gaps = 10/178 (5%)

Query: 568 STTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNA 627
           S +S  S+     TNS   S    S  + AT S S    S    + NS+S     T+  A
Sbjct: 303 SESSTTSSGANTATNS--DSSTTSSGASTATNSESSTTSSGASTATNSESST---TSSGA 357

Query: 628 QPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVP-SSPMSRKPQKLKSSKSLRPKESS 686
             A +       S  S   +S SS+ S+ +  ++   SS  S       +S+S      +
Sbjct: 358 STATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGA 417

Query: 687 GNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGP 744
             +TN +++++S    SG     +S   V S+ S +++ +  H+        V+ + P
Sbjct: 418 STATNSESSTTS----SGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKP 471


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 93/382 (24%), Positives = 141/382 (36%), Gaps = 52/382 (13%)

Query: 407  PPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSA 466
            PPQP     PAPP  +  P   P   +P+ +     +       + P+P    A +   A
Sbjct: 2393 PPQP----SPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGA 2448

Query: 467  PIDPPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEKL---DCHYSGHHPQPASFCT 523
                    + P  P    E   +L  E       +++ E L   +   +G   +P S  +
Sbjct: 2449 --------KGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLS 2500

Query: 524  FGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNS 583
             GS     G     + W            K  +  L ++  P P  T   S   P   + 
Sbjct: 2501 LGSYPPAAGSSEPKAPW-----------PKATDGDLAQE--PGPGLTFEDSGN-PKSPDK 2546

Query: 584  VPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQS 643
                Q G    A  + S+S    SS+  S +S S  + G+    +       D  C    
Sbjct: 2547 AQAEQDG----AEESESSSS---SSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGG 2599

Query: 644  RQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGS 703
            R  S++SS  ++P+  SS  SS          SS S     SS +S++  ++SSS+S  S
Sbjct: 2600 RNCSAASSRAASPASSSSSSSS----------SSSSSSSSSSSSSSSSSSSSSSSSSSSS 2649

Query: 704  GKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVA-HSGPPYPSTVTSSHSIGLNCVT 762
                 +SS     SSSSSSSSSSSS S      +C +     P P+   S+ +      T
Sbjct: 2650 SSSSSSSS-----SSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKAT 2704

Query: 763  NKANAVNVRHDQSGRGPPTGSP 784
             +A          G+  P   P
Sbjct: 2705 KQAGKARPSAHSPGKKTPAPQP 2726



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 92/397 (23%), Positives = 142/397 (35%), Gaps = 61/397 (15%)

Query: 401  HPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPA 460
            +P  + P  PL     + P + + P   P  V      P     P   +P+ P    CPA
Sbjct: 2352 NPTDEVPSTPLALEPSSTPGSKKSP---PEPVDKRAKAPKARPAPPQPSPAPPAFTSCPA 2408

Query: 461  QQGGSAPIDPPPVHESPHP--PLPATEPA---SRLSSEEG-----EGDDKEESVEKLDCH 510
             +   A +  P    +P P   +PAT P    +R + E G        ++ E + KLD H
Sbjct: 2409 PEP-FAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLD-H 2466

Query: 511  YSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTT 570
                 P+                          +    L++ +   A  W++    P + 
Sbjct: 2467 EGVTSPKSK------------------------KAKEALLLREDPGAGGWQE----PKSL 2498

Query: 571  SPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPA 630
              + +  P   +S P +    +          P L      +P S           AQ  
Sbjct: 2499 LSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPD--------KAQAE 2550

Query: 631  ASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNST 690
              GA +   S  S   SSSSSS S+ SG         S    + +  K+      +G   
Sbjct: 2551 QDGAEESESSSSSSSGSSSSSSSSSSSG---------SETEGEEEGDKNGDGGCGTGGR- 2600

Query: 691  NCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTV 750
            NC  ASS  +  +     +SS     SSSSSSSSSSSS S  S   +  + S     S+ 
Sbjct: 2601 NCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2660

Query: 751  TSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAES 787
            +SS S   +  T   ++     D++   P  G  A++
Sbjct: 2661 SSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQA 2697



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 27/82 (32%), Positives = 35/82 (42%), Gaps = 9/82 (10%)

Query: 1   MSERAADDVRGEPRRAAAAAGGAAAAAARQQQ----QQQQQQQPPPPQPQRQQHPPPPPR 56
           M    A DV G P   A A  G A  AARQ +     ++ +   P P+P     PPPP  
Sbjct: 283 MCNGGAGDV-GLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPP-- 339

Query: 57  RTRPEDGGPGAASTSAAAMATV 78
              P  G P   + + A + TV
Sbjct: 340 --APPKGPPAPPAATPAGVYTV 359



 Score = 32.0 bits (71), Expect = 2.8
 Identities = 21/51 (41%), Positives = 28/51 (54%)

Query: 169  RHSSSSKPPLAVPPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSS 219
            R+ S++    A P +S  S   S S S   S+S S+ SSS    S+SSSSS
Sbjct: 2600 RNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2650



 Score = 31.6 bits (70), Expect = 3.7
 Identities = 43/150 (28%), Positives = 60/150 (40%), Gaps = 33/150 (22%)

Query: 193  SKSKGG---------SASGSNRSSSGGVLSASSSSSKLLKSPK----EKLQL----RGNT 235
            SK+ GG         S  G NR +    L  S  SS+  K  +     K+++    RG  
Sbjct: 1656 SKTSGGCGRYLTPYDSLLGKNRKALAKGLGLSLKSSREGKHKRAAKTRKMEVGFKARGQP 1715

Query: 236  RPMHPIQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKS---AVGPTCPATVSSLVKPGLNC 292
            +  H    S V      T S + E+         LK    A GP+     SS + P L C
Sbjct: 1716 KSAHSPFASEVSSYSYNTDSEEDEEF--------LKDEWPAQGPS-----SSKLTPSLLC 1762

Query: 293  PSIPKPTLPSPGQILNGKGLPAPPTLEKKP 322
              + K +  + G  L  +GL AP TL+ KP
Sbjct: 1763 SMVAKNSKAAGGPKLTKRGLAAPRTLKPKP 1792



 Score = 30.8 bits (68), Expect = 6.2
 Identities = 24/70 (34%), Positives = 31/70 (44%)

Query: 150  CNDCNQVVKPQAFQSHYERRHSSSSKPPLAVPPTSVFSFFPSLSKSKGGSASGSNRSSSG 209
            C+  +      A  S      SSSS    +   +S  S   S S S   S+S S+ SSS 
Sbjct: 2602 CSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2661

Query: 210  GVLSASSSSS 219
               S+SSSSS
Sbjct: 2662 SSSSSSSSSS 2671



 Score = 30.4 bits (67), Expect = 8.1
 Identities = 22/66 (33%), Positives = 31/66 (46%)

Query: 154  NQVVKPQAFQSHYERRHSSSSKPPLAVPPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLS 213
            ++   P +  S      SSSS    +   +S  S   S S S   S+S S+ SSS    S
Sbjct: 2607 SRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2666

Query: 214  ASSSSS 219
            +SSSS+
Sbjct: 2667 SSSSST 2672


>gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 83/306 (27%), Positives = 110/306 (35%), Gaps = 48/306 (15%)

Query: 176 PPLAVPPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNT 235
           P    PP S F   P        S+S S+ SSS    S+SSSSS   K P   L      
Sbjct: 75  PQYDYPPQSTFK--PKAEVPSSSSSSSSSSSSSSSSSSSSSSSSSQAKKPDPPLPPAFGA 132

Query: 236 RPMHPIQQSRVPHGRIMTPSVKVEKI--HPKMDGTLLKS--AVGPTCPATVSSLVKPGLN 291
            P  P+  +  P     TP   +  +  H  + G L +   A GP         V PGL 
Sbjct: 133 -PPPPLFDAAFP-----TPQWGIVDLSGHQHLFGNLKRGGPASGPG--------VTPGLG 178

Query: 292 CPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVID 351
            P+     LP+P Q     G PA    +   +D    R+   K L ER F     CGV  
Sbjct: 179 APAGAPGPLPAPSQ--TPPGPPAAAACDPTKDDKGYFRRL--KYLMERRFP----CGV-- 228

Query: 352 LDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPL 411
                 C +S    +H L Q   V    + ++  +   +       LIRH    +   P 
Sbjct: 229 ------CQKSFKQSSH-LVQHMLVHSGERPYECGVC-GRTYNHVSSLIRHRRCHKDVPPA 280

Query: 412 RDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPA--QQGGSAPID 469
               P P      PH  P G+    +    A+ P   +   P  P  PA    G +AP  
Sbjct: 281 AGGPPQP-----GPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAG 335

Query: 470 ---PPP 472
              PPP
Sbjct: 336 VGVPPP 341



 Score = 32.0 bits (71), Expect = 2.8
 Identities = 24/97 (24%), Positives = 35/97 (36%), Gaps = 6/97 (6%)

Query: 385 LLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASK 444
           L  EH            P  Q PPQP    +  PP+++ +P       +PS S    +S 
Sbjct: 47  LYGEHAKAVAALPCAPGPPPQPPPQPPPPQYDYPPQSTFKPKAE----VPSSSSSSSSSS 102

Query: 445 PKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPL 481
               + S          +    P+  PP   +P PPL
Sbjct: 103 SSSSSSSSSSSSSSSQAKKPDPPL--PPAFGAPPPPL 137



 Score = 31.6 bits (70), Expect = 3.7
 Identities = 27/91 (29%), Positives = 35/91 (38%), Gaps = 10/91 (10%)

Query: 657 SGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVH 716
           + L   P  P    PQ         P+ +        ++SSS+S  S             
Sbjct: 56  AALPCAPGPPPQPPPQPPPPQYDYPPQSTFKPKAEVPSSSSSSSSSSSSS---------- 105

Query: 717 SSSSSSSSSSSSHSMESFRKNCVAHSGPPYP 747
           SSSSSSSSSSSS + +       A   PP P
Sbjct: 106 SSSSSSSSSSSSQAKKPDPPLPPAFGAPPPP 136


>gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 83/306 (27%), Positives = 110/306 (35%), Gaps = 48/306 (15%)

Query: 176 PPLAVPPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNT 235
           P    PP S F   P        S+S S+ SSS    S+SSSSS   K P   L      
Sbjct: 75  PQYDYPPQSTFK--PKAEVPSSSSSSSSSSSSSSSSSSSSSSSSSQAKKPDPPLPPAFGA 132

Query: 236 RPMHPIQQSRVPHGRIMTPSVKVEKI--HPKMDGTLLKS--AVGPTCPATVSSLVKPGLN 291
            P  P+  +  P     TP   +  +  H  + G L +   A GP         V PGL 
Sbjct: 133 -PPPPLFDAAFP-----TPQWGIVDLSGHQHLFGNLKRGGPASGPG--------VTPGLG 178

Query: 292 CPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVID 351
            P+     LP+P Q     G PA    +   +D    R+   K L ER F     CGV  
Sbjct: 179 APAGAPGPLPAPSQ--TPPGPPAAAACDPTKDDKGYFRRL--KYLMERRFP----CGV-- 228

Query: 352 LDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPL 411
                 C +S    +H L Q   V    + ++  +   +       LIRH    +   P 
Sbjct: 229 ------CQKSFKQSSH-LVQHMLVHSGERPYECGVC-GRTYNHVSSLIRHRRCHKDVPPA 280

Query: 412 RDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPA--QQGGSAPID 469
               P P      PH  P G+    +    A+ P   +   P  P  PA    G +AP  
Sbjct: 281 AGGPPQP-----GPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAG 335

Query: 470 ---PPP 472
              PPP
Sbjct: 336 VGVPPP 341



 Score = 32.0 bits (71), Expect = 2.8
 Identities = 24/97 (24%), Positives = 35/97 (36%), Gaps = 6/97 (6%)

Query: 385 LLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASK 444
           L  EH            P  Q PPQP    +  PP+++ +P       +PS S    +S 
Sbjct: 47  LYGEHAKAVAALPCAPGPPPQPPPQPPPPQYDYPPQSTFKPKAE----VPSSSSSSSSSS 102

Query: 445 PKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPL 481
               + S          +    P+  PP   +P PPL
Sbjct: 103 SSSSSSSSSSSSSSSQAKKPDPPL--PPAFGAPPPPL 137



 Score = 31.6 bits (70), Expect = 3.7
 Identities = 27/91 (29%), Positives = 35/91 (38%), Gaps = 10/91 (10%)

Query: 657 SGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVH 716
           + L   P  P    PQ         P+ +        ++SSS+S  S             
Sbjct: 56  AALPCAPGPPPQPPPQPPPPQYDYPPQSTFKPKAEVPSSSSSSSSSSSSS---------- 105

Query: 717 SSSSSSSSSSSSHSMESFRKNCVAHSGPPYP 747
           SSSSSSSSSSSS + +       A   PP P
Sbjct: 106 SSSSSSSSSSSSQAKKPDPPLPPAFGAPPPP 136


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 95/371 (25%), Positives = 144/371 (38%), Gaps = 48/371 (12%)

Query: 569  TTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQ 628
            + +P+ T  P  T++  TS         A  ++ P    S  ++P + SVP   T + + 
Sbjct: 3185 SATPVDTSTPVTTSTEATSS------TTAEGTSIPTSTPSEGMTPLT-SVPVSNTPVASS 3237

Query: 629  PAASGAMDPVCSMQSRQVSS-SSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSG 687
             A+  +  PV S      S+ +SSSP T  G S   S+P          S+   P  S  
Sbjct: 3238 EASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTP----------SEGSTPLTSMP 3287

Query: 688  NSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSS-------SSSSSSHSMESFRKNCVA 740
             ST    ASS TS  S      S+P+  +S +SSS       S  +S++S  S     ++
Sbjct: 3288 VSTTTV-ASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMS 3346

Query: 741  HSGPPYPSTVTSSHSI----GLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVN 796
             S  P  S+  S+ S         VT    A        G   PT SP+E    ++ M  
Sbjct: 3347 FSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPV 3406

Query: 797  SSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDK--LIGKKRKCSPSSSSINNSSSKPT 854
            S+                PV S    + S TP+D   L+    + S SS +I   +S PT
Sbjct: 3407 ST---------------TPVVSSEVNTLSTTPVDSNTLVTTSTEAS-SSPTIAEGTSLPT 3450

Query: 855  KVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQDISSPCLRTGISATSPQSPDLKSKGTS 914
                  +     M  + T   +      S    D S+P   +  + +SP + ++ S  TS
Sbjct: 3451 STTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTS 3510

Query: 915  LTAENSTGRNN 925
               E ST   N
Sbjct: 3511 TAGEGSTPLTN 3521



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 90/368 (24%), Positives = 142/368 (38%), Gaps = 27/368 (7%)

Query: 567 PSTTSPISTRIPHRTNSVPTSQCGVS----YLAAATVSTSPVLLSSTCIS---PNSKSVP 619
           P T  P+ST +   + +  TS   V        A+  S+SP     T I+   P+  S P
Sbjct: 394 PLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTP 453

Query: 620 AHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKS 679
                ++  P AS       ++ +  V S +   ++    SS P++ ++  P    S  S
Sbjct: 454 LTSMPVSTTPVASSEAS---NLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGS 510

Query: 680 LRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCV 739
             P  S   ST    ASS  S  S      S+P+   S +SSSS++    S+ +      
Sbjct: 511 T-PLTSMSVST-MPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPT------ 562

Query: 740 AHSGPPYPSTVTSSHSIGLNCV-TNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSS 798
             S P   ST  ++  +    V +++A+  +     S     T S A S    +   +  
Sbjct: 563 --STPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMP 620

Query: 799 DSTLS-LGPFIHQ---SNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSIN-NSSSKP 853
            ST S  G  I     S  L  +S  S + S TP+D           +SSS     +S P
Sbjct: 621 TSTYSERGTTITSMSVSTTLVASSEAS-TLSTTPVDSNTPVTTSTEATSSSTTAEGTSMP 679

Query: 854 TKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQDISSPCLRTGISATSPQSPDLKSKGT 913
           T      +     M    T+  +      S    D S+P   +  +++SP + D  S  T
Sbjct: 680 TSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPT 739

Query: 914 SLTAENST 921
           S  +E ST
Sbjct: 740 STPSEGST 747



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 84/368 (22%), Positives = 140/368 (38%), Gaps = 42/368 (11%)

Query: 568  STTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNA 627
            S  S +ST  P  T++  T+    S     T  TS  + + +  SP   S+P   T + +
Sbjct: 762  SEASTLSTT-PLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTS 820

Query: 628  QPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSS-------PMSRKPQKLK----- 675
              A++ +  PV S      S+  SS  TP+  +S+P+S       P++  P         
Sbjct: 821  PEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATS 880

Query: 676  --SSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMES 733
              S+ S  P ++S   TN   A SS +   G     S+P     S+  +S   S+  + S
Sbjct: 881  AISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTP--GEGSTPLTSMPDSTTPVVS 938

Query: 734  FRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSV 793
                 ++ +     + VT+S     +  T +  ++       G  P T +P       ++
Sbjct: 939  SEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSH----TL 994

Query: 794  MVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKP 853
            + NS  STLS  P                  S+TPL          SP  ++    +S P
Sbjct: 995  VANSEASTLSTTPV----------------DSNTPLTT---STEASSPPPTA--EGTSMP 1033

Query: 854  TKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQDISSPCLRTGISATSPQSPDLKSKGT 913
            T      +     M  + T+  +      S    D S+P      +++S  + D  S  T
Sbjct: 1034 TSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPT 1093

Query: 914  SLTAENST 921
            S  +E ST
Sbjct: 1094 STYSEGST 1101



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 93/384 (24%), Positives = 158/384 (41%), Gaps = 32/384 (8%)

Query: 568 STTSPISTRIPHRTN--------SVPTSQCGVSYLAAATVSTSPVLLSS-TCISPNSKSV 618
           S T+P ST IP  TN        S+P S   V+   A T+ T+PV +S+   IS  + S 
Sbjct: 197 SPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSS 256

Query: 619 P--AHGTTLNAQPAASGAMDPVCSMQ---SRQVSSSSSSPSTPSGLSSVP---SSPMSRK 670
           P  A G +L +  A SG   P+  M       VSS +S+ ST    +++P   S+  S  
Sbjct: 257 PTTAEGPSL-SNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSS 315

Query: 671 PQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHS 730
           P   + + S+     +  ST   +  +ST   +  +    S   V +S+  ++S+  S  
Sbjct: 316 PTTAEGT-SIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSL 374

Query: 731 MESFRKNCVAHSGPPYPSTVTSSHSIGLNCV-TNKANAVNVRHDQSGRGPPTGSPAESIK 789
             +     +  S     ST  ++  +    V +++A+  +     S     T S A S  
Sbjct: 375 PTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSP 434

Query: 790 RMSVMVNSSDSTLSLGPFIHQS---NELPVNSHGSFSHSHTPLDK----LIGKKRKCSPS 842
             +   + + ST S G     S   +  PV S  + + S TP+D         +   SP 
Sbjct: 435 TTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPP 494

Query: 843 SSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNS-SLLHQDISSPCLRTGISAT 901
           ++ +N+  +        P  +        T+P A    ++ S    D S+P   +  +++
Sbjct: 495 TAEVNSMPTSTPSEGSTPLTS----MSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASS 550

Query: 902 SPQSPDLKSKGTSLTAENSTGRNN 925
           S  +P+  S  TS  +E ST   N
Sbjct: 551 SSTTPEGTSIPTSTPSEGSTPLTN 574



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 93/390 (23%), Positives = 153/390 (39%), Gaps = 61/390 (15%)

Query: 569  TTSPISTRIPHRT--NSVPTSQCGVSYLAAATVSTSPV-----LLSSTCISPNSKSVPAH 621
            T+ P ST     T   S P S   V+   A+T+ST+PV     +++ST +S  S   PA 
Sbjct: 1796 TSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVS--SSPTPAE 1853

Query: 622  GTTLNAQPAASGAM---------DPVCSMQSRQVSSS--------------SSSPSTPSG 658
            GT++     + G+            V S ++  +S++              SSSP+T  G
Sbjct: 1854 GTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADG 1913

Query: 659  LSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSS 718
             S   S+P   +P          P  S   ST    ASS  +  S       +P+  +S 
Sbjct: 1914 SSMPTSTPREGRP----------PLTSIPVSTTTV-ASSEINTLSTTLADTRTPVTTYSQ 1962

Query: 719  SSSSSSSSSSHSM--ESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSG 776
            +SSS +++   SM   ++ +     +  P  +T+  S        T    +        G
Sbjct: 1963 ASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEG 2022

Query: 777  RGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKK 836
               PT +   SI+  +     S+ T  L   +  S  L V+S G+ + S TP+D      
Sbjct: 2023 SSSPTTAGGTSIQTST----PSERTTPLAG-MPVSTTLVVSSEGN-TLSTTPVDSKTQVT 2076

Query: 837  RKCSPSSSSINNSSSKPTKVAK--VPAVNNVHMKHTGTI-PGAQGLMNSSLLHQDISSPC 893
                 SSS+    SS          P + ++ +  T    P A  L  + +   D +SP 
Sbjct: 2077 NSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPV---DSNSPV 2133

Query: 894  LRTGISATSPQSPDLKSKGTSLTAENSTGR 923
                I++T   S  + ++GTS+     + R
Sbjct: 2134 ----ITSTEVSSSPIPTEGTSMQTSTYSDR 2159



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 93/393 (23%), Positives = 164/393 (41%), Gaps = 59/393 (15%)

Query: 565  PVPSTTSPISTRIPHRT--NSVPTSQCGVSYLAAATVSTSPV-----LLSST--CISPNS 615
            P   T+ P ST    RT   S+P +   V+  A + +ST+PV     + +ST  C SP +
Sbjct: 1321 PAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTT 1380

Query: 616  K-------SVPAHGTT-LNAQPAASGAMDPVCSMQSRQVSSS--------------SSSP 653
                    S P+ GTT L + P ++    PV S ++  +S++              +SSP
Sbjct: 1381 SEGTSMPNSNPSEGTTPLTSIPVST---TPVVSSEASTLSATPVDTSTPGTTSAEATSSP 1437

Query: 654  STPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPL 713
            +T  G+ S+P+S  S     LKS             +N   A+S  S  S     ++SP+
Sbjct: 1438 TTAEGI-SIPTSTPSEGKTPLKSIP----------VSNTPVANSEASTLSTTPVDSNSPV 1486

Query: 714  LVHS--SSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVR 771
            +  +  SSS + +  +S ++ +  +   A +  P  +T  +S  I     T    +  V 
Sbjct: 1487 VTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVT 1546

Query: 772  HDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDK 831
                    PT +   S++  +    S+  T      +  S  L V+S  + + S TP+D 
Sbjct: 1547 TYSQASSSPTTADGTSMQTSTYSEGSTPLT-----SLPVSTMLVVSSEAN-TLSTTPIDS 1600

Query: 832  --LIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTI-PGAQGLMNSSLLHQD 888
               +    + S S+++  +S +  T     P + ++ +  T    P A  L  + +   D
Sbjct: 1601 KTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPV---D 1657

Query: 889  ISSPCLRTGISATSPQSPDLKSKGTSLTAENST 921
             +SP + +   ++SP   +  S  TS   E  T
Sbjct: 1658 SNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRT 1690



 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 88/392 (22%), Positives = 147/392 (37%), Gaps = 69/392 (17%)

Query: 567  PSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISP---NSKSVPAHGT 623
            PS  SP+ T IP  T  V + +       A+T+ST+PV  +S  I+    +S   PA GT
Sbjct: 1626 PSEGSPLLTSIPVSTTPVASPE-------ASTLSTTPVDSNSPVITSTEVSSSPTPAEGT 1678

Query: 624  -----------------TLNAQPAASGAMDPVCSM---QSRQVSSSS---SSPSTPSGLS 660
                             T+   P AS A+  + +     S  V++S+   SSP+T  G S
Sbjct: 1679 SMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTS 1738

Query: 661  SVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSS 720
               S+P            S  P  SS  ST       +++  +      SSP    +  +
Sbjct: 1739 MPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSP--TTAEGT 1796

Query: 721  SSSSSSSSHSMESFRKNCVAHS--GPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRG 778
            S  +S+ S  M       V+H+       ST++++     + V       +      G  
Sbjct: 1797 SIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTS 1856

Query: 779  PPTGSPAESIKRM-------SVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDK 831
              T +P+E    +       + + +S  +TLS  P +      PV ++   S S T  D 
Sbjct: 1857 IATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAV---TSTPVTTYAQVSSSPTTAD- 1912

Query: 832  LIGKKRKCSPSSSSINNSSSKPTKVAKV--PAVNNVHMKHTGTIPGAQGLMNSSLLHQDI 889
                              SS PT   +   P + ++ +  T         ++++L   D 
Sbjct: 1913 -----------------GSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTL--ADT 1953

Query: 890  SSPCLRTGISATSPQSPDLKSKGTSLTAENST 921
             +P      +++SP + D  S  T   +E ST
Sbjct: 1954 RTPVTTYSQASSSPTTADGTSMPTPAYSEGST 1985



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 91/412 (22%), Positives = 161/412 (39%), Gaps = 79/412 (19%)

Query: 569  TTSPISTRIPHRTN----SVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT- 623
            +T+P+ T IP  T+    S PT+  G S +  +T S     L+S  +S    +VP  G+ 
Sbjct: 2890 STTPVDTSIPVTTSTEGSSSPTTAEGTS-MPISTPSEVSTPLTSILVS----TVPVAGSE 2944

Query: 624  --TLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLR 681
              TL+  P  +    PV +      + +SSSP+T  G S   S+P  R+      S S  
Sbjct: 2945 ASTLSTTPVDTRT--PVTTS-----AEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTM 2997

Query: 682  PKESSGNSTNCQ---------------NASSSTSGGSG----KKRKNSSPLL-------- 714
            P  SS  ST  +               ++S +T+ G+G       + S+PL         
Sbjct: 2998 PVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTP 3057

Query: 715  -----------------------VHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVT 751
                                      SSS + +  +S  + ++ +     +G P  +T  
Sbjct: 3058 VAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPV 3117

Query: 752  SSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQS 811
            +S +I     T    +  V         PT S   S+   +    S+  T     ++  S
Sbjct: 3118 TSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLT-----YMPVS 3172

Query: 812  NELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAK--VPAVNNVHMKH 869
              L V+S  S + S TP+D           +SS+    +S PT      +  + +V + +
Sbjct: 3173 TMLVVSSEDS-TLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSN 3231

Query: 870  TGTIPGAQGLMNSSLLHQDISSPCLRTGISATSPQSPDLKSKGTSLTAENST 921
            T        +++++ +  D ++P   +  +++SP + +  S  TS  +E ST
Sbjct: 3232 TPVASSEASILSTTPV--DSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGST 3281



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 96/424 (22%), Positives = 166/424 (39%), Gaps = 89/424 (20%)

Query: 567  PSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISP---NSKSVPAHGT 623
            PS  SP+ T IP  T  V + +       A+T+ST+PV  +S  I+    +S  +P  GT
Sbjct: 2097 PSEGSPLLTSIPLSTTPVASPE-------ASTLSTTPVDSNSPVITSTEVSSSPIPTEGT 2149

Query: 624  T------------LNAQPAASG--AMDPVCSMQSRQVSSSS---------SSPSTPSGLS 660
            +            L + P ++   A   + ++ +  V +S+         SSP+T  G S
Sbjct: 2150 SMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTS 2209

Query: 661  ---SVPSS--------PMSRKPQKLKSSKSL--------RPKESSGNSTNCQNASSSTSG 701
               S PS         P+S  P     + +L         P  +S  +T+    +  TS 
Sbjct: 2210 MPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSI 2269

Query: 702  GSGKKRKNSSPL--------LVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPY---PSTV 750
             +    + ++PL        LV +S  S+ S++   S   F  +  A S PP     S  
Sbjct: 2270 PTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMP 2329

Query: 751  TSSHSIGLNCVTN-----------KANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSD 799
            TS+ S G   +T            + + ++     +     T S A S    +   +   
Sbjct: 2330 TSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPT 2389

Query: 800  STLSLGPFIHQS---NELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPT-K 855
            ST S G     S   + +PV S  + +HS TP+D         +P ++S   SSS  T +
Sbjct: 2390 STYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVD-------TSTPVTTSTEASSSPTTAE 2442

Query: 856  VAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQDISSPCLRTGISATSPQSPDLKSKGTSL 915
               +P          GT P A   ++++ +    +     T +  ++P +   ++  +  
Sbjct: 2443 GTSIP----TSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPT 2498

Query: 916  TAEN 919
            TAE+
Sbjct: 2499 TAED 2502



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 83/383 (21%), Positives = 142/383 (37%), Gaps = 38/383 (9%)

Query: 567  PSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVST----SPVLLSSTCI--SPNSK---- 616
            P T+ P+STR+   + +   S   V      T ST    SP     T I  SP S+    
Sbjct: 1102 PLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTP 1161

Query: 617  --SVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKL 674
              S+P   T + +  A + +  PV S      S+ +SSP   + ++S+P+S    +   L
Sbjct: 1162 LASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPL 1221

Query: 675  KSSKSLR-PKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMES 733
             S      P  SS  ST   +   +++  +     +SSP     +S  +S++S   ++ +
Sbjct: 1222 TSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLT 1281

Query: 734  FRKNCVAHSGPPYPST-----------VTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTG 782
                       P  ST           V +S+ +  +    +  ++       GR P T 
Sbjct: 1282 SIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTS 1341

Query: 783  SPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPS 842
             P  +    +++ +S+ S LS  P     N  PV +      S T  +   G     S  
Sbjct: 1342 IPVNT----TLVASSAISILSTTPV---DNSTPVTTSTEACSSPTTSE---GTSMPNSNP 1391

Query: 843  SSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQDISSPCLRTGISATS 902
            S      +S P     V +     +  T       G  ++    +  SSP    GIS  +
Sbjct: 1392 SEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSA----EATSSPTTAEGISIPT 1447

Query: 903  PQSPDLKSKGTSLTAENSTGRNN 925
                + K+   S+   N+   N+
Sbjct: 1448 STPSEGKTPLKSIPVSNTPVANS 1470



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 90/396 (22%), Positives = 151/396 (38%), Gaps = 73/396 (18%)

Query: 569  TTSPISTRIPHRT--NSVPTSQCGVSYLAAATVSTSPVLLSSTCISP---NSKSVPAHGT 623
            T  PIST     T   S+P S   V+   A+T+ST+PV  +S  ++    +S   PA GT
Sbjct: 3034 TGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGT 3093

Query: 624  TL-----------------NAQPAASGAMDPVCSMQ---SRQVSSSS---SSPSTPSGLS 660
            ++                 +  P  S A+  + +     S  V++S+   SSP+T  G +
Sbjct: 3094 SMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEG-T 3152

Query: 661  SVP-------SSPMSRKP-------QKLKSSKSLRPKESSGNSTNCQNASSSTSG-GSGK 705
            S+P       S+P++  P           S+ S  P ++S   T    A+SST+  G+  
Sbjct: 3153 SMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSI 3212

Query: 706  KRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKA 765
                 S  +   +S   S++  + S  S        S  P    +T+S     +  T + 
Sbjct: 3213 PTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTP----LTTSTEASSSPPTAEG 3268

Query: 766  NAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHS 825
             ++       G  P T  P  +    + + +S  STLS  P        PV ++   S  
Sbjct: 3269 TSMPTSTPSEGSTPLTSMPVST----TTVASSETSTLSTTP---ADTSTPVTTYSQAS-- 3319

Query: 826  HTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLL 885
                            SS  I + +S PT      +    +M  + T   +      S  
Sbjct: 3320 ----------------SSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTT 3363

Query: 886  HQDISSPCLRTGISATSPQSPDLKSKGTSLTAENST 921
              D S+P   +  ++ SP + +  S  TS  +E +T
Sbjct: 3364 PVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTT 3399



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 89/400 (22%), Positives = 156/400 (39%), Gaps = 58/400 (14%)

Query: 570  TSPISTRIPHRTNSVPT-SQCGVSYLAAATVS--TSPVLLSSTCISPNSKSVPAHGTTLN 626
            TS +ST     +  V T SQ G S   A   S  TS     ST ++    SVP     + 
Sbjct: 2355 TSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLT----SVPVSTMPVV 2410

Query: 627  AQPAASGAMDPVCSMQSRQVSS-SSSSPSTPSGLSSVPSSPMSRKPQKLKS--------- 676
            +  A++ +  PV +      S+ +SSSP+T  G +S+P+SP S     L S         
Sbjct: 2411 SSEASTHSTTPVDTSTPVTTSTEASSSPTTAEG-TSIPTSPPSEGTTPLASMPVSTTPVV 2469

Query: 677  -----SKSLRPKESSGNSTNCQNASSS-----------TSGGSGKKRKNSSPLLVHSSSS 720
                 + S  P ++S   T    ASSS           ++   G     S P+     +S
Sbjct: 2470 SSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVAS 2529

Query: 721  SSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPP 780
              +S+ S+  ++S   N    +     S+ TS+    +   T    +  +R       P 
Sbjct: 2530 PEASTLSTTPVDS---NSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPL 2586

Query: 781  TGSPAESIKR----MSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKK 836
              S A ++       S+ V +S  T S  P   +   +P+++    S S T +  L+   
Sbjct: 2587 ASSEASTLSTTPVDTSIPVTTSTET-SSSPTTAKDTSMPISTPSEVSTSLTSI--LVSTM 2643

Query: 837  RKCSPSSSSINNSS-------SKPTKVAKVPAVNNVHMKHTGTIPGAQG------LMNSS 883
               S  +S+++ +        +  T  +  P         T T PG +       L++++
Sbjct: 2644 PVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTST-PGERSTPLTNILVSTT 2702

Query: 884  LLHQDISSPCLRTGISATSPQSPDLKSKGTSLTAENSTGR 923
            LL    +S    T +  ++P +   ++  +  TAE ++ R
Sbjct: 2703 LLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMR 2742



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 95/391 (24%), Positives = 150/391 (38%), Gaps = 75/391 (19%)

Query: 567  PSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLS---STCISPNSKSVPAHGT 623
            PS  S   TR+P  T  V +S+        +T+ST+P   S   +T    +S S  A GT
Sbjct: 1037 PSEGSTPLTRMPVSTTMVASSE-------TSTLSTTPADTSTPVTTYSQASSSSTTADGT 1089

Query: 624  TLNAQPAASGAMDPVCS--MQSRQVSSS----------------------SSSPSTPSGL 659
            ++     + G+  P+ S  + +R V SS                      SSSP+T  G 
Sbjct: 1090 SMPTSTYSEGS-TPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEG- 1147

Query: 660  SSVPSSPMSRKPQKLKSS--KSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHS 717
            +S+P+SP S     L S    +     S  N+ +     S T   +  +  +  P    +
Sbjct: 1148 TSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVT 1207

Query: 718  SSSSSSSSSSSHSMESF--RKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQS 775
            S  +S+    S  + S   R   VA S     ST+++S       VT  A   +      
Sbjct: 1208 SMPTSTPGERSTPLTSMPVRHTPVASS---EASTLSTSPVDTSTPVTTSAETSSSPTTAE 1264

Query: 776  GRGPPTGSPAE------SIKRMSVMVNSSD-STLSLGPFIHQSNELPVNSHGSFSHSHTP 828
            G   PT + +E      SI   + +V S + STL   P      + PV +    S S TP
Sbjct: 1265 GTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPV---DTKGPVVTSNEVSSSPTP 1321

Query: 829  LDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQD 888
             +           +S   +  S   T +  +P VN        T+  +  +   S    D
Sbjct: 1322 AE----------GTSMPTSTYSEGRTPLTSIP-VNT-------TLVASSAISILSTTPVD 1363

Query: 889  ISSPCLRTGISATSPQSPDLKSKGTSLTAEN 919
             S+P   +  + +SP +    S+GTS+   N
Sbjct: 1364 NSTPVTTSTEACSSPTT----SEGTSMPNSN 1390



 Score = 38.5 bits (88), Expect = 0.030
 Identities = 79/310 (25%), Positives = 118/310 (38%), Gaps = 34/310 (10%)

Query: 551  VEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTC 610
            V   L + L   +P   S  S +ST  P  T ++ T+  G S  ++ T +    + +ST 
Sbjct: 2631 VSTSLTSILVSTMPVASSEASTLSTT-PVDTRTLVTTSTGTS--SSPTTAEGSSMPTST- 2686

Query: 611  ISPNSKSVPAHG----TTLNAQPAASG-AMDPVCSMQSRQVSS-SSSSPSTPSGLSSVPS 664
              P  +S P       TTL A   AS  +  PV +      S+ +SSSP+T  G S   S
Sbjct: 2687 --PGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRIS 2744

Query: 665  SPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSS 724
            +P            S  P  SS  ST    A  ++   +     +SSP     +S  +S+
Sbjct: 2745 TPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTST 2804

Query: 725  SSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSP 784
             S + +           +  P   T  +S   G    T    +  V         PT   
Sbjct: 2805 PSETST---------PLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPT--T 2853

Query: 785  AESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSS 844
            AE I  + +   S  STL     +   +  PV S  + + S TP+D  I       P ++
Sbjct: 2854 AEGIV-VPISTASEGSTLLTSIPV---STTPVASSEASTLSTTPVDTSI-------PVTT 2902

Query: 845  SINNSSSKPT 854
            S   SSS  T
Sbjct: 2903 STEGSSSPTT 2912



 Score = 38.1 bits (87), Expect = 0.039
 Identities = 75/326 (23%), Positives = 122/326 (37%), Gaps = 40/326 (12%)

Query: 564  PPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT 623
            P +PS  + +S       +S PT+  G + +  +T S    LL++  ISP S   P+  +
Sbjct: 3774 PSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEAS 3833

Query: 624  TLNAQP------------AASGAMDPVCSMQSRQVSSSSSSPSTPSGLS-----SVPSSP 666
            TL+  P            A S ++    +     ++S  S+P T   +S     S P + 
Sbjct: 3834 TLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGAS 3893

Query: 667  MSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSS 726
            ++  P  L +S +  P   + ++     A++ +     +     + + + S+  +SS++ 
Sbjct: 3894 IASTP-PLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTA- 3951

Query: 727  SSHSMESFRKNCVAHSGPPYPST-----VTSSHSIGLNCVTNKANAVNVRHDQSGRGPPT 781
                 + F     A S P   ST      TSS S   +  T K          +     T
Sbjct: 3952 -----DVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVT 4006

Query: 782  GSPAESIKR-MSVMVNSSDSTLSLGPFIHQSNEL---PVNSHGSFSHSHTPLDKLIGKKR 837
             S A S  R  S    +S STLS     H S  +   PV      S   T     I    
Sbjct: 4007 MSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTI---- 4062

Query: 838  KCSPSSSSINNSSSKPTKVAKVPAVN 863
               P +    +SS+ PT  A    VN
Sbjct: 4063 ---PPTFPPAHSSTPPTTSASSTTVN 4085



 Score = 35.0 bits (79), Expect = 0.33
 Identities = 82/345 (23%), Positives = 133/345 (38%), Gaps = 50/345 (14%)

Query: 569  TTSPISTRIPHRT--NSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSK--SVPA--HG 622
            T+ P ST     T   ++P S   V+   A+T+ST+PV  S+T ++ +S+  S PA    
Sbjct: 3505 TSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVD-SNTFVTSSSQASSSPATLQV 3563

Query: 623  TTLNAQPAASGAMDPVCSMQSRQ--VSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSL 680
            TT+     + G+      + S     SS +S+PSTPS   S P +  +            
Sbjct: 3564 TTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTST------------ 3611

Query: 681  RPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVA 740
               +S+   T  +  +   S  S    + S+PL +   S++S + S + +  +     V 
Sbjct: 3612 ---QSNSTPTPPEVITLPMSTPS----EVSTPLTIMPVSTTSVTISEAGTASTLP---VD 3661

Query: 741  HSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDS 800
             S P   ST  SS     + VT +   + +     G  P T  P  + +    + +S  S
Sbjct: 3662 TSTPVITSTQVSS-----SPVTPEGTTMPIWTPSEGSTPLTTMPVSTTR----VTSSEGS 3712

Query: 801  TLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVP 860
            TLS    +      PV +      S   LD            S  +  S+   T +    
Sbjct: 3713 TLSTPSVV---TSTPVTTSTEAISSSATLDS------TTMSVSMPMEISTLGTTILVSTT 3763

Query: 861  AVNNVHMKHTGTIPGAQGLMNSSLLHQDISSPCLRTGISATSPQS 905
             V       T +IP     M+ +   +  SSP    G + T P S
Sbjct: 3764 PVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEG-TTTMPMS 3807



 Score = 34.3 bits (77), Expect = 0.56
 Identities = 70/327 (21%), Positives = 121/327 (37%), Gaps = 54/327 (16%)

Query: 639 CSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSS 698
           CS      S  SS  S   G+SS   +P          ++S    ES+ +ST    +S+ 
Sbjct: 85  CSTNPEMTSIESSVTSDTPGVSSTRMTP----------TESRTTSESTSDSTTLFPSSTE 134

Query: 699 TSGGSGKKRKNSSPLLVHSSSSSSSSSS--SSHSMESFRKNCVAHSGPPYPSTVTSSHSI 756
            +           P+   S  S SS+ +  S+  + SF             + +T+S   
Sbjct: 135 DTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQA 194

Query: 757 GLNCVTNKANAVNVRHDQSGRGPPTGSPAESIK--------------RMSVMVN-----S 797
             +  T ++  +    +  G  P T  PA ++K               +S  V      S
Sbjct: 195 SSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQAS 254

Query: 798 SDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCS-----PSSSSI-----N 847
           S  T + GP +  SN  P  S GS   +  PL  ++    + S     P++++I      
Sbjct: 255 SSPTTAEGPSL--SNSAP--SGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITST 310

Query: 848 NSSSKPTKVAKVPAVNNVHMKHT--------GTIPGAQGLMNS-SLLHQDISSPCLRTGI 898
            +SS PT         + + + +         T+P A   M++ S+   D S+    +  
Sbjct: 311 EASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTE 370

Query: 899 SATSPQSPDLKSKGTSLTAENSTGRNN 925
            ++ P + +  S  TS  +E ST   N
Sbjct: 371 PSSLPTTAEATSMLTSTLSEGSTPLTN 397


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 125/508 (24%), Positives = 189/508 (37%), Gaps = 62/508 (12%)

Query: 416  PAPPRTSQ----EPHQNPHGVIPSES-KPFVASKPKPHTPSLPRPPGCPAQQGGSAPI-- 468
            P PP  +      P    H + PS S K F  +     TP LP      A  G + P+  
Sbjct: 937  PTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATP-LPVTYASSASTGHTTPLHV 995

Query: 469  -DPPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSR 527
             D   V      PLP T P+S  +         + S E      S  H  P    +F S 
Sbjct: 996  TDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSE------STGHVTPLPVTSFSSA 1049

Query: 528  QIGRG--YYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVP 585
              G      V D+          L V    +A      P   + TS  ST   H T+   
Sbjct: 1050 STGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTG--HATSLPV 1107

Query: 586  TSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQ 645
            T    VS     T  T+P+ ++ T     S +   H T+L     +S +      +    
Sbjct: 1108 TDTSSVS-----TGHTTPLPVTDT-----SSASTGHATSLPVTDTSSVSTGHTTPLHVTD 1157

Query: 646  VSSSSSSPSTP---SGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTN--CQNASSSTS 700
             SS+S+  +TP   + LSSV +   +  P    SS       S+G++T     + SS+++
Sbjct: 1158 ASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSS------ASTGHATPLLVTDTSSAST 1211

Query: 701  GGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNC 760
            G       +++PL V  +SS S+  ++S  +         H+  P P T TSS S G   
Sbjct: 1212 G-------HATPLPVTDASSVSTDHATSLPVTIPSAASTGHT-TPLPVTDTSSASTGQAT 1263

Query: 761  VTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHG 820
                 +  +V    +   P T + + S   ++ +  +S S+ S G     +  LPV S  
Sbjct: 1264 SLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTG----HATPLPVTSLS 1319

Query: 821  SFSHSHT-PLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGL 879
            S S   T PL          SPSS+S  +++  P   A   +  +    H      A   
Sbjct: 1320 SASTGDTMPLP-------VTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTG 1372

Query: 880  MNSSLLHQDISSPCL--RTGISATSPQS 905
              + L    +SS      T +  TSP S
Sbjct: 1373 QATPLPVTSLSSVSTGDTTPLPVTSPSS 1400



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 95/357 (26%), Positives = 149/357 (41%), Gaps = 67/357 (18%)

Query: 565  PVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTT 624
            P+P  TSP S    H T   P    G+S  +A+T  T+P+ ++ T     S +   H T 
Sbjct: 3728 PLP-VTSPSSASTGHAT---PLPVTGLS--SASTGDTTPLPVTDT-----SSASTRHATP 3776

Query: 625  LNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPS-SPMSRKPQKLKSSKSLRPK 683
            L     +S + D    +    VSS+S+  +TP  ++S  S S     P  +  + S+   
Sbjct: 3777 LPVTDTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSV--- 3833

Query: 684  ESSGNSTNCQNAS-SSTSGG----------SGKKRKNSSPLLVHSSSSSSSSSSSSHSME 732
             S+G++T+    S SS S G          S     +++PL V S+SS S+  ++   + 
Sbjct: 3834 -STGHATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVT 3892

Query: 733  SFRKNCVAHSGPPYPSTVTSSHSIGLNC---VTNKANAVNVRH---------DQSGRG-- 778
            S       H+  P P T TSS S G      VTN A++++  H           + RG  
Sbjct: 3893 SPSSASTGHA-TPVPVTSTSSASTGDTTPLPVTN-ASSLSTGHATPLHVTSPSSASRGDT 3950

Query: 779  ---PPTGSPAESIKRMSVMVNSSDSTLSLG------------PFIHQSNELPVNSHGSFS 823
               P T + + S    + +  +S S++S G                Q+  LPV S  S S
Sbjct: 3951 STLPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVS 4010

Query: 824  HSH-TPLDKLIGKKRKCSPSSSSINNSSSKP-TKVAKVPAVNNVHMKHTGTIPGAQG 878
                TPL   I       PSS+S  +++S P T  + V   +   +  T T   + G
Sbjct: 4011 TGDTTPLPVTI-------PSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTG 4060



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 94/387 (24%), Positives = 158/387 (40%), Gaps = 49/387 (12%)

Query: 565  PVPST-TSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT 623
            P+P T TS  ST   H T S+P +       +A+T   +P+  + T     S +   H T
Sbjct: 2816 PLPVTDTSSASTG--HAT-SLPVTDTS----SASTGHATPLPDTDT-----SSASTGHAT 2863

Query: 624  TLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPK 683
             L     +S ++    S+     SS S+  +TP  ++S PSS  +     L  + +    
Sbjct: 2864 LLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVTS-PSSASTGHATPLPVTDTSSAS 2922

Query: 684  ESSGNSTNCQNASSSTSG---------GSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESF 734
                N  +  + SS+++G          S     +++PL V S SS S+  ++   + S 
Sbjct: 2923 TGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTPLPVTSP 2982

Query: 735  RKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVM 794
                  H+  P P T TSS S G        +  +     +   P T + + S  + + +
Sbjct: 2983 SSASTGHT-TPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPL 3041

Query: 795  VNSSDSTLSLGPFIHQSNELPVNSHGSFSHSH-TPL---DKLIGKKRKCSP----SSSSI 846
              +S S++S G     +  LPV S  S S  H TPL   D       + +P    S SS+
Sbjct: 3042 PVTSLSSVSTG----DTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSV 3097

Query: 847  NNSSSKPTKVAKVPAVNNVH---MKHTGTIPGAQGLMNSSLLHQDISS---------PCL 894
            +   + P  V    + +  H   +  T T   + G   +SL   D SS         P  
Sbjct: 3098 STGDTTPLPVTSPSSASTGHATSLPVTDTSSASTG-DTTSLPVTDTSSAYTGDTTSLPVT 3156

Query: 895  RTGISATSPQSPDLKSKGTSLTAENST 921
             T  S+T   +P L ++ +S++  ++T
Sbjct: 3157 DTSSSSTGDTTPLLVTETSSVSTGHAT 3183



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 65/271 (23%), Positives = 111/271 (40%), Gaps = 24/271 (8%)

Query: 565  PVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTT 624
            P+P  TSP S    H T  +P +       +A+T  T+P+ +++        + P H T+
Sbjct: 1600 PLP-VTSPSSASTGH-TTPLPVTDTS----SASTGDTTPLPVTNASSLSTGHATPLHVTS 1653

Query: 625  LNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSL---- 680
             ++  A++G   P+    +   S+  ++P   +GLSS  +   +R P    SS S     
Sbjct: 1654 PSS--ASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSASTGQAT 1711

Query: 681  -RPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCV 739
              P  S  + +         +  S     ++SPLLV  +SS+S+  ++   +        
Sbjct: 1712 PLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVST 1771

Query: 740  AHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRG---PPTGSPAESIKRMSVMVN 796
            AH+  P P T  SS S      T +    +V    +G+    P T   + S    + +  
Sbjct: 1772 AHA-TPLPVTGLSSASTD---DTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPV 1827

Query: 797  SSDSTLSLGPFIHQSNELPVNSHGSFSHSHT 827
            +  S+ S G     +  LPV    S S  HT
Sbjct: 1828 TDASSASTG----DTTSLPVTIPSSASSGHT 1854



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 76/324 (23%), Positives = 125/324 (38%), Gaps = 52/324 (16%)

Query: 565  PVPST-TSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT 623
            P+P T  S +ST   H T+   TS   VS     T  T+P+ ++S   +    + P H T
Sbjct: 2256 PLPVTDASSVSTG--HATSLPVTSLSSVS-----TGDTTPLPVTSPSSASTGHATPLHVT 2308

Query: 624  TLNAQPAASGAMDPVCSMQSRQVSSSSSSPST-PSGLSSVPSSPMSRKPQKLKSSKSLRP 682
              ++         PV S+ S     ++  P T PS  S+  ++P+        S+    P
Sbjct: 2309 DASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTTP 2368

Query: 683  -------KESSGNST--NCQNASSSTSGG---------SGKKRKNSSPLLVHSSSSSSSS 724
                     SSG++T     +ASS+++G          S     +++ L V   SS+S+ 
Sbjct: 2369 LPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSASTGHATHLPVTGLSSASTG 2428

Query: 725  SSSSHSMESFRKNCVAHSGP---------------PYPSTVTSSHSIGLNCVTNKANAVN 769
             ++   + +       H+ P               P P T TSS S G        +A +
Sbjct: 2429 DTTRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASS 2488

Query: 770  VRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPL 829
            V    + R P T   + S    + +  +   + S G     +  LPV +  S S  H   
Sbjct: 2489 VSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSASTG----DTTPLPVTNASSLSTRHAT- 2543

Query: 830  DKLIGKKRKCSPSSSSINNSSSKP 853
                      SPSS+S  +++S P
Sbjct: 2544 -----SLHVTSPSSASTGHATSLP 2562



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 88/381 (23%), Positives = 153/381 (40%), Gaps = 34/381 (8%)

Query: 563  IPPVPST--TSPIS-TRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVP 619
            IP   ST  T+P+  T     +    TS       + +T  T+P+ ++ST  +      P
Sbjct: 1237 IPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTP 1296

Query: 620  AHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPST-PSGLSSVPSSPMSRKPQKLKSSK 678
             H T+ ++         PV S+ S     +   P T PS  S+  ++P+        S+ 
Sbjct: 1297 LHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTG 1356

Query: 679  SLRP---KESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFR 735
               P    ++S  ST  Q      +  S     +++PL V S SS+S+  ++   +    
Sbjct: 1357 HTTPLHVTDASSASTG-QATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTS 1415

Query: 736  KNCVAHSGP---PYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMS 792
                 H+ P      S+V++ H+  L      A +       +   P T + + S  + +
Sbjct: 1416 SASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTG----HTTPLPVTDTSSASTGQAT 1471

Query: 793  VMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSH-TPLDKLIGKKRKCSPSSSSINNSSS 851
             ++ +  S++S G     +  LPV S  S S  H TPL          SPSS+S  +++ 
Sbjct: 1472 SLLVTDTSSVSTG----DTTPLPVTSTSSASTGHVTPL-------HVTSPSSASTGHATP 1520

Query: 852  KP-TKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQDISSPCLRTGISATSP-QSPDLK 909
             P T ++     + + +  T     + G   + L   D SS  + TG +   P  SP   
Sbjct: 1521 LPVTSLSSASTGDTMPLPVTSPSSASTG-DTTPLPVTDASS--VSTGHTTPLPVTSPSSA 1577

Query: 910  SKG--TSLTAENSTGRNNADT 928
            S G  T L   +++  +  DT
Sbjct: 1578 STGHTTPLPVTDTSSASKGDT 1598



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 76/321 (23%), Positives = 127/321 (39%), Gaps = 40/321 (12%)

Query: 565  PVPSTTSPISTRIP--HRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPA-H 621
            PV ST+S  +  +   H T+    S   V+ L   + S++    ++  +  ++ SV   H
Sbjct: 3586 PVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGH 3645

Query: 622  GTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTP---SGLSSVPSSPMSRKPQKLKSSK 678
             T L    A+S +      +     SS+S+  +TP   + LSSV +   +  P    SS 
Sbjct: 3646 ATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDASSA 3705

Query: 679  SLR---------PKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSH 729
            S           P   S   T     +S +S  +G    +++PL V   SS+S+  ++  
Sbjct: 3706 STGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTG----HATPLPVTGLSSASTGDTTPL 3761

Query: 730  SMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPP---TGSPAE 786
             +         H+  P P T TSS S      T +    +V    +G   P   T + + 
Sbjct: 3762 PVTDTSSASTRHA-TPLPVTDTSSASTD---DTTRLPVTDVSSASTGHATPLPVTSTSSA 3817

Query: 787  SIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSH-TPLDKLIGKKRKCSPSSSS 845
            S    + +  +  S++S G     +  LPV S  S S  H TPL             +SS
Sbjct: 3818 STGDTTPLPVTDTSSVSTG----HATSLPVTSRSSASTGHATPLP---------VTDTSS 3864

Query: 846  INNSSSKPTKVAKVPAVNNVH 866
            ++   + P  V    +V+  H
Sbjct: 3865 VSTGHATPLPVTSTSSVSTGH 3885



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 90/377 (23%), Positives = 146/377 (38%), Gaps = 49/377 (12%)

Query: 565  PVPSTTSPIS---TRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAH 621
            PV  T+S  +   T +P    S  ++      L   T S S    +   ++  S +   H
Sbjct: 3138 PVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGH 3197

Query: 622  GTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTP---SGLSSVPSSPMSRKPQKLKSSK 678
             T L+    +S +      +     SS S+  +TP   +GLSS  +   +R P    SS 
Sbjct: 3198 ATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISS- 3256

Query: 679  SLRPKESSGNST--NCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRK 736
                  S+G +T     N SS ++G       ++ PL V S SS+S+  ++   + S   
Sbjct: 3257 -----ASTGQATPLPVTNTSSVSTG-------DTMPLPVTSPSSASTGHATPLPVTSTSS 3304

Query: 737  NCVAHSGPPYPSTVTSSHSIGLNC---VTNKANAVNVRHDQSGRGPPTGSPAESIKRMSV 793
                H+  P P T TSS S G      VT+ ++A            P+ +       + V
Sbjct: 3305 ASTGHA-TPVPVTSTSSASTGHTTPLPVTDTSSASTGDTTPLPVTSPSSASTGHTTPLHV 3363

Query: 794  MVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSH-TPLDKLIGKKRKCSPSSSSINNSSSK 852
             + SS ST         ++ LPV    S S  H TPL             +SS++   + 
Sbjct: 3364 TIPSSAST-------GDTSTLPVTGASSASTGHATPLP---------VTDTSSVSTGHAT 3407

Query: 853  PTKVAKVPAVNNVHMKHTG-TIPGAQGLMNSSLLHQDISSPCLRTGISATSPQSPDLKSK 911
            P  V  + +V+      TG T P      +S+   Q    P       +T   +P L + 
Sbjct: 3408 PLPVTSLSSVS------TGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTD 3461

Query: 912  GTSLTAENSTGRNNADT 928
             +S++  ++T     DT
Sbjct: 3462 ASSVSTGHATPLPVTDT 3478



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 116/530 (21%), Positives = 182/530 (34%), Gaps = 67/530 (12%)

Query: 410  PLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPID 469
            P RD H     T        HG IP  +    +  P    P+L          G S+P  
Sbjct: 834  PSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTS 893

Query: 470  PPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQI 529
            P     SP      +  A    +    G D      +    +S   P P S  + G    
Sbjct: 894  P---SASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSITSTGLTSP 950

Query: 530  GRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQC 589
                +      +           K     L     P+P T +  S    H T   P    
Sbjct: 951  QTETHTLSPSGS----------GKTFTTALISNATPLPVTYAS-SASTGHTT---PLHVT 996

Query: 590  GVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSS 649
              S ++    +  PV       SP+S S   H T L     +S +   V  +     SS+
Sbjct: 997  DASSVSTGHATPLPV------TSPSSVST-GHTTPLPVTDTSSESTGHVTPLPVTSFSSA 1049

Query: 650  SSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNAS-SSTSGGSGKKRK 708
            S+  STP  ++   S+                   S+G+ T     S SS S G      
Sbjct: 1050 STGDSTPLPVTDTSSA-------------------STGHVTPLPVTSLSSASTG------ 1084

Query: 709  NSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAV 768
            +++PL V  +SS+S+  ++S  +         H+  P P T TSS S G        +  
Sbjct: 1085 DTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHT-TPLPVTDTSSASTGHATSLPVTDTS 1143

Query: 769  NVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSH-T 827
            +V    +     T + + S  + + +  +S S++S G     +  LPV S  S S  H T
Sbjct: 1144 SVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTG----DTTPLPVTSPSSASTGHAT 1199

Query: 828  PL---DKLIGKKRKCSP------SSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQG 878
            PL   D         +P      SS S ++++S P  +    +  +           A  
Sbjct: 1200 PLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSAST 1259

Query: 879  LMNSSLLHQDISSPCLRTGISATSPQSPDLKSKGTSLTAENSTGRNNADT 928
               +SLL  D SS  + TG +   P +    +    +T  + T  ++A T
Sbjct: 1260 GQATSLLVTDTSS--VSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSAST 1307



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 65/285 (22%), Positives = 116/285 (40%), Gaps = 34/285 (11%)

Query: 596  AATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPST 655
            +A+ STSP   ++   +  ++S  A G T  ++PA+SG+     S  +   SSS +S +T
Sbjct: 757  SASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSR--TTSAGTATPSSSGASGTT 814

Query: 656  PSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASS-------STSGGSGKKRK 708
            PSG   + +S  + +     SS   R   ++ ++T   +AS+       ST   S     
Sbjct: 815  PSGSEGISTSGETTR----FSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPG 870

Query: 709  NSSPLLVHSSSS------SSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVT 762
               P L  +S++      SS +S S+   E+   + +A +      T TS  S  ++  +
Sbjct: 871  TFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQT----QRTRTSRGSDTISLAS 926

Query: 763  NKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSF 822
               +  +           TG  +   +  ++  + S  T +    I  +  LPV    S 
Sbjct: 927  QATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTA-LISNATPLPVTYASSA 985

Query: 823  SHSH-TPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVH 866
            S  H TPL             +SS++   + P  V    +V+  H
Sbjct: 986  STGHTTPLH---------VTDASSVSTGHATPLPVTSPSSVSTGH 1021



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 100/427 (23%), Positives = 155/427 (36%), Gaps = 52/427 (12%)

Query: 449  TPSLPRPPGCPAQQGGSAPID---PPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVE 505
            T  LP      A  G + P+    P  V      PLP T P+S  +     G      V 
Sbjct: 3694 TTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSAST-----GHATPLPVT 3748

Query: 506  KLDCHYSGHH-PQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIP 564
             L    +G   P P +  +  S +      V D+          L V    +A      P
Sbjct: 3749 GLSSASTGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTRLPVTDVSSASTGHATP 3808

Query: 565  PVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTT 624
               ++TS  ST     T  +P +          T S S    +S  ++  S +   H T 
Sbjct: 3809 LPVTSTSSASTG---DTTPLPVTD---------TSSVSTGHATSLPVTSRSSASTGHATP 3856

Query: 625  LNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMS--RKPQKLKSSKSLRP 682
            L     +S +      +     SS S+  +TP  ++S PSS  +    P  + S+ S   
Sbjct: 3857 LPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTS-PSSASTGHATPVPVTSTSS--- 3912

Query: 683  KESSGNST--NCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVA 740
              S+G++T     NASS ++G       +++PL V S SS+S   +S+  +         
Sbjct: 3913 -ASTGDTTPLPVTNASSLSTG-------HATPLHVTSPSSASRGDTSTLPVTDASSASTG 3964

Query: 741  HSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDS 800
            H+  P P T  SS S G        +  +    Q+   P T   + S    + +  +  S
Sbjct: 3965 HA-TPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPS 4023

Query: 801  TLSLGPFIHQSNELPVNSHGSFSHSH-TPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKV 859
            + S G     +  LPV    S S  H TPL            S+SS +   + P  V   
Sbjct: 4024 SASSG----HTTSLPVTDASSVSTGHGTPLP---------VTSTSSASTGDTTPLPVTDT 4070

Query: 860  PAVNNVH 866
             + +  H
Sbjct: 4071 SSASTGH 4077



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 69/271 (25%), Positives = 115/271 (42%), Gaps = 35/271 (12%)

Query: 565  PVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTT 624
            P+P  TSP S    H T  + T         A++VST     +S  ++  S     H T 
Sbjct: 2064 PLP-VTSPSSASTGHATPLLVTD--------ASSVSTGHA--TSLLVTDASSVSTGHATA 2112

Query: 625  LNAQPAASGAMDPVCSMQSRQVSSSSSSPSTP---SGLSSVPSSPMSRKPQKLKSSKSLR 681
            L+   A+S +      +     SS+S+  +TP   +  SSV +   +  P    SS    
Sbjct: 2113 LHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDTSS---- 2168

Query: 682  PKESSGNSTN--CQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCV 739
               S+G++T+    + SS+++G       +++PL V  +SS+S+  ++   + S      
Sbjct: 2169 --ASTGHATSLPVTDTSSASTG-------HATPLPVTDTSSASTGQATPLPVTSPSSAST 2219

Query: 740  AHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSD 799
             H+  P   T TSS S G        +  +     +   P T + + S    + +  +S 
Sbjct: 2220 GHA-IPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSL 2278

Query: 800  STLSLGPFIHQSNELPVNSHGSFSHSH-TPL 829
            S++S G     +  LPV S  S S  H TPL
Sbjct: 2279 SSVSTG----DTTPLPVTSPSSASTGHATPL 2305



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 100/495 (20%), Positives = 170/495 (34%), Gaps = 69/495 (13%)

Query: 408  PQPLRDPHPAPPR-TSQEPHQNPHGVIPSESKPFVASKPKP----HTPSLPRPPGCPAQQ 462
            P P+  P  A    T+  P  +   V    + P   + P      HT  LP      A +
Sbjct: 1536 PLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASK 1595

Query: 463  GGSAPI---DPPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCHYSGH----- 514
            G + P+    P         PLP T+     +S    GD     V       +GH     
Sbjct: 1596 GDTTPLPVTSPSSASTGHTTPLPVTD-----TSSASTGDTTPLPVTNASSLSTGHATPLH 1650

Query: 515  ----------HPQPASFCTFGSRQIGRGYYVFDSRWNRLRC--ALNLMVEKHLNAQLWKK 562
                      H  P    +  S   G    +  +  +         L V    +A   + 
Sbjct: 1651 VTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSASTGQA 1710

Query: 563  IPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVP--- 619
             P   ++ S +ST     T  +P +    S  +A+T   SP+L++    +   ++ P   
Sbjct: 1711 TPLPVTSLSSVSTG---DTTPLPVT----SPSSASTGHASPLLVTDASSASTGQATPLPV 1763

Query: 620  --------AHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKP 671
                    AH T L     +S + D    +    VSS+S+  + P  ++S PSS  +   
Sbjct: 1764 TDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTS-PSSASTGDT 1822

Query: 672  QKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSM 731
              L  + +         S      SS++SG        S P+   + +SS S+  ++  +
Sbjct: 1823 TPLPVTDASSASTGDTTSLPVTIPSSASSG-----HTTSLPV---TDASSVSTGHATSLL 1874

Query: 732  ESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRM 791
             +   +       P P T T+S S G     +  +A +V    +   P T   + S    
Sbjct: 1875 VTDASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDT 1934

Query: 792  SVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSS 851
            + +  +S S+ S G     +  LPV    S    H     +          +SS++   +
Sbjct: 1935 TPLPVTSPSSASSG----HTTPLPVTDASSVPTGHATSLPV--------TDASSVSTGHA 1982

Query: 852  KPTKVAKVPAVNNVH 866
             P  V    +V+  H
Sbjct: 1983 TPLPVTDASSVSTGH 1997



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 59/261 (22%), Positives = 99/261 (37%), Gaps = 15/261 (5%)

Query: 570  TSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQP 629
            T   S    H T+ + T    VS     T  T+P+ ++ T  +    + P H T  ++  
Sbjct: 1860 TDASSVSTGHATSLLVTDASSVS-----TGDTTPLPVTDTNSASTGDTTPLHVTDASSVS 1914

Query: 630  AASGAMDPVCSMQSRQVSSSSSSPST-PSGLSSVPSSPM---SRKPQKLKSSKSLRPKES 685
                   PV S+ S     ++  P T PS  SS  ++P+            + SL   ++
Sbjct: 1915 TGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDA 1974

Query: 686  SGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPP 745
            S  ST        T   S     +++PL V  +SS S+  ++   + S        +  P
Sbjct: 1975 SSVSTGHATPLPVTD-ASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDT-TP 2032

Query: 746  YPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLG 805
             P T TSS S G +      +  +V    +   P T   + S    + ++ +  S++S G
Sbjct: 2033 LPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTG 2092

Query: 806  PFIHQSNELPVNSHGSFSHSH 826
                 +  L V    S S  H
Sbjct: 2093 ----HATSLLVTDASSVSTGH 2109



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 71/314 (22%), Positives = 119/314 (37%), Gaps = 37/314 (11%)

Query: 570  TSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQP 629
            T+P+    P   ++  T+   V+     T S S    +S  ++  S +   H T+L    
Sbjct: 2126 TTPLPVTSPSSASTGDTTPLPVT----DTSSVSTGHATSLPVTDTSSASTGHATSLPVTD 2181

Query: 630  AASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNS 689
             +S +      +     SS+S+  +TP  ++S  S+        L +  S     S+G +
Sbjct: 2182 TSSASTGHATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTS---SASTGQA 2238

Query: 690  TNCQNAS-SSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPS 748
            T     S SS S G      +++PL V  +SS S+  ++S  + S        +  P P 
Sbjct: 2239 TPLPVTSLSSASTG------DTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDT-TPLPV 2291

Query: 749  TVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPF- 807
            T  SS S G     +  +A +     +   P T   + S    + +  +S S+ S G   
Sbjct: 2292 TSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHAT 2351

Query: 808  -IH----------QSNELPVNSHGSFSHSH-TPLDKLIGKKRKCSPSSSSINNSSSKPTK 855
             +H           +  LPV S  S S  H TPL             +SS +   + P  
Sbjct: 2352 PLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLP---------VTDASSASTGDTTPLP 2402

Query: 856  VAKVPAVNNVHMKH 869
            V    + +  H  H
Sbjct: 2403 VTDTSSASTGHATH 2416



 Score = 37.0 bits (84), Expect = 0.087
 Identities = 67/325 (20%), Positives = 127/325 (39%), Gaps = 31/325 (9%)

Query: 563  IPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHG 622
            +   PS ++  +T +P    S  +++   S    +  S S    +S  ++  S +   H 
Sbjct: 2515 VTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHA 2574

Query: 623  TTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTP------SGLSSVPSSPMSRKPQKLKS 676
            T L     +S +      +      S+S+  +TP      S  S+  ++P+        S
Sbjct: 2575 TPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTPLPVTDTSSAS 2634

Query: 677  SKSLRP-------KESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSH 729
            +    P         S+G++T   + +S +S  +G    +++PL V  +SS S+  ++S 
Sbjct: 2635 TGHATPLPVTNTSSVSTGHATPL-HVTSPSSASTG----HTTPLPVTDASSVSTGHATSL 2689

Query: 730  SMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIK 789
             +         H+    P T+ SS S G        +A +V    +   P T + + S  
Sbjct: 2690 PVTDASSVFTGHA-TSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTG 2748

Query: 790  RMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSH-TPL---DKLIGKKRKCSP---- 841
              + +  +  S++S G     +  LP+ S  S S    TPL   D       + +P    
Sbjct: 2749 HATPLPVTDASSVSTG----HATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVT 2804

Query: 842  SSSSINNSSSKPTKVAKVPAVNNVH 866
            S SS++   + P  V    + +  H
Sbjct: 2805 SLSSVSTGDTTPLPVTDTSSASTGH 2829



 Score = 37.0 bits (84), Expect = 0.087
 Identities = 62/263 (23%), Positives = 102/263 (38%), Gaps = 40/263 (15%)

Query: 592  SYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSS 651
            S  + +T  T+P+L++       S     H T L     +S +      +     SS+S+
Sbjct: 3445 SLSSVSTGDTTPLLVTDA-----SSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSAST 3499

Query: 652  SPSTPSGLSSVPS-SPMSRKPQKLKSSKSLRPKESSGNST--NCQNASSSTSGG------ 702
              +TP  ++S+ S S     P  +  + S+    S+G++T     + SS+++G       
Sbjct: 3500 GQATPLPVTSLSSVSTGDTTPLLVTDASSV----STGHATPLPVTDTSSASTGDTTRLPV 3555

Query: 703  ---SGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGP--------------- 744
               S      ++PL V   SSSSS  ++   + S       H  P               
Sbjct: 3556 TDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVT 3615

Query: 745  PYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSL 804
            P P T TSS S G        +A +V    +   P T + + S    + +  +  S+ S 
Sbjct: 3616 PLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSAST 3675

Query: 805  GPFIHQSNELPVNSHGSFSHSHT 827
            G    Q+  LPV S  S S   T
Sbjct: 3676 G----QATPLPVTSLSSVSTGDT 3694



 Score = 32.0 bits (71), Expect = 2.8
 Identities = 42/175 (24%), Positives = 72/175 (41%), Gaps = 29/175 (16%)

Query: 570  TSPISTRIPHRTNSVPTSQCGVSYLAAATVST---SPVLLSSTCISPNSKSVP------- 619
            T+P+   IP   +S  T+   V+   A++VST   +P+ ++ST  +    + P       
Sbjct: 4014 TTPLPVTIPSSASSGHTTSLPVT--DASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTS 4071

Query: 620  ----AHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLK 675
                 H T L     +S +      +    +SS S+  +TP  +SS  S+          
Sbjct: 4072 SASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGHATPLAVSSATSA-------STV 4124

Query: 676  SSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHS 730
            SS S    E+ G +T     S  T G  G++   S P     +  S+  S++ H+
Sbjct: 4125 SSDSPLKMETPGMTT----PSLKTDG--GRRTATSPPPTTSQTIISTIPSTAMHT 4173


>gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens]
          Length = 796

 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 42/94 (44%), Positives = 48/94 (51%), Gaps = 15/94 (15%)

Query: 16  AAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQH------------PPPPPRRTRPEDG 63
           AAAAA  AAAAAA+QQQQQQQQQQ    Q Q+QQ             P      +  E  
Sbjct: 90  AAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGSSKPAVLAAPSGLERY 149

Query: 64  GPGAASTSAAAMATVGERR---PLPSPEVMLGQS 94
           G  AA+ +AAA A   E+R     P P V LG S
Sbjct: 150 GLSAAAAAAAAAAAAVEQRSRFEYPPPPVSLGSS 183



 Score = 34.7 bits (78), Expect = 0.43
 Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 15/86 (17%)

Query: 11  GEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPP-----------QPQRQQHPPPPPRRTR 59
           G  R   +AA  AAAAAA   +Q+ + + PPPP            P     P   P+ T 
Sbjct: 145 GLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPVSLGSSSHTARLPNGLGGPNGFPKPT- 203

Query: 60  PEDGGP---GAASTSAAAMATVGERR 82
           PE+G P     +  S++A A+V  RR
Sbjct: 204 PEEGPPELNRQSPNSSSAAASVASRR 229


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 65/214 (30%), Positives = 86/214 (40%), Gaps = 32/214 (14%)

Query: 565  PVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSP----VLLSSTCISPNSKSVPA 620
            PVPS  S  S  +  +T  V  SQ   S   A T S++     +L       P+S     
Sbjct: 2450 PVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEP 2509

Query: 621  HGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSP-------------- 666
              +T   QP+A  A+ P    +S   SSSSSS S+ S  SS  SS               
Sbjct: 2510 PASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLP 2569

Query: 667  ------MSRKPQKLKSSKSL----RPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVH 716
                  + R P    + K      RP E +      +++SSS+S  S     +SS     
Sbjct: 2570 VQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSS---- 2625

Query: 717  SSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTV 750
            SSSSSSSSSSSS S  S   +       P P  +
Sbjct: 2626 SSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQAL 2659



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 81/301 (26%), Positives = 122/301 (40%), Gaps = 59/301 (19%)

Query: 564  PPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT 623
            P  PS +   S R P  ++ +  +        A     SPV    +  S  S+ + A  T
Sbjct: 2411 PSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPV---PSAFSDQSRCLIAQTT 2467

Query: 624  TL-NAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRP 682
             +  +Q  +SGA           V++++SS    +G+ SVP+  +              P
Sbjct: 2468 PVAGSQSLSSGA-----------VATTTSSAGDHNGMLSVPAPGV--------------P 2502

Query: 683  KESSGN---STNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCV 739
                G    ST  Q  S+  +    K+R++SS     SSSSSSSSSSSS S  S   +  
Sbjct: 2503 HSDVGEPPASTGAQQPSALAALQPAKERRSSS-----SSSSSSSSSSSSSSSSSSSSSSG 2557

Query: 740  AHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSD 799
            + S     S++     + L  V +   A      + GR PP  +PA+  +R S   +SS 
Sbjct: 2558 SSSSDSEGSSLPVQPEVALKRVPSPTPAPK-EAVREGR-PPEPTPAKRKRRSSSSSSSSS 2615

Query: 800  STLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKV 859
            S+ S       S+    +S  S S S              S SSSS ++SSS P+     
Sbjct: 2616 SSSS------SSSSSSSSSSSSSSSS--------------SSSSSSSSSSSSSPSPAKPG 2655

Query: 860  P 860
            P
Sbjct: 2656 P 2656



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 75/307 (24%), Positives = 114/307 (37%), Gaps = 54/307 (17%)

Query: 567 PSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPN-SKSVPAHGTTL 625
           P+  S   ++   R  S  T+    S  A  + S      S T  S + S +   H T L
Sbjct: 232 PTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTAL 291

Query: 626 --NAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPK 683
              +   ASG      +  S   ++S+  PS+P   +  PSSP   K +  K   + RP 
Sbjct: 292 AGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPS 351

Query: 684 ESSGNSTNCQNASSST------SGGSGKKRK----NSSPLLVHSSSSSSSSSSSSHSMES 733
            S   S+      + T       GGS +       +  P+   S +S +   S   S E 
Sbjct: 352 PSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEK 411

Query: 734 FRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSV 793
             ++  + S PP P     S                 RH  S    P  +PA    R   
Sbjct: 412 LPQSSSSESSPPSPQPTKVS-----------------RHASSSPESPKPAPAPGSHR--- 451

Query: 794 MVNSSDSTLSLGPFIHQSNELPVNSHG----SFSHSHTPLDKLIGKKRKCSPSSSSINNS 849
            ++SS ++ +              SHG      SHSHTP  + +G+ R  SP+++    S
Sbjct: 452 EISSSPTSKN-------------RSHGRAKRDKSHSHTP-SRRMGRSR--SPATAKRGRS 495

Query: 850 SSK-PTK 855
            S+ PTK
Sbjct: 496 RSRTPTK 502



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 93/428 (21%), Positives = 155/428 (36%), Gaps = 66/428 (15%)

Query: 371  QRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPH 430
            ++  +  RR R    L+  ++K + +  +R   S   P P +     PPR S+       
Sbjct: 750  KKSRISSRRSRS---LSSPRSKAKSRLSLRRSLSGSSPCP-KQKSQTPPRRSRS------ 799

Query: 431  GVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRL 490
                  S+P   S+  P        P  P +Q    P        SPHP + +  P  + 
Sbjct: 800  ----GSSQPKAKSRTPPRRSRSSSSP--PPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQG 853

Query: 491  SSEEGEGDDKEESVEKLDCHYSGHHPQ-----PASFCTFGSRQIGRGYYVFDSRWNRLRC 545
            S    + +++  + ++  C  S   P+     P+     GS        V  S   R   
Sbjct: 854  SITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSP----PRVKSSTPPRQSP 909

Query: 546  ALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVL 605
            + +   +  + A +  +      ++SP  +R+  RT   P     VS  +       P  
Sbjct: 910  SRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRT--TPRRSRSVSPCSNVESRLLPRY 967

Query: 606  LSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSS 665
              S   SP++K  P        + + SG++ P   ++++          TP G    PS 
Sbjct: 968  SHSGSSSPDTKVKP----ETPPRQSHSGSISPYPKVKAQ----------TPPG----PSL 1009

Query: 666  PMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSG---------KKRKNSSPLLVH 716
              S+ P   + SK    +   G+ + C    SST  G           K +  +SP   H
Sbjct: 1010 SGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSP--DH 1067

Query: 717  SSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSG 776
             S +SS     SHS ES      + + P    + +SS       VT  A+   +R D   
Sbjct: 1068 RSDTSSPEVRQSHS-ESPSLQSKSQTSPKGGRSRSSSP------VTELASRSPIRQD--- 1117

Query: 777  RGPPTGSP 784
            RG  + SP
Sbjct: 1118 RGEFSASP 1125



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 82/391 (20%), Positives = 148/391 (37%), Gaps = 54/391 (13%)

Query: 562  KIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVP-A 620
            + PP  S +S  S+  P + +  P+ Q      + ++ S  P + S T     S + P A
Sbjct: 809  RTPPRRSRSS--SSPPPKQKSKTPSRQ------SHSSSSPHPKVKSGTPPRQGSITSPQA 860

Query: 621  HGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKS- 679
            +  ++  Q  +     P   ++SR  S  S S S+P  + S  S+P  + P +  S +  
Sbjct: 861  NEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKS--STPPRQSPSRSSSPQPK 918

Query: 680  ----LRPKESSGNSTNCQNASSSTSGGSGKKRKNSSP-------LLVHSSSSSSSSSSSS 728
                + P++ S + ++  + S  TS  + ++ ++ SP       LL   S S SSS  + 
Sbjct: 919  VKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTK 978

Query: 729  HSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTG---SPA 785
               E+  +   + S  PYP                          Q+  GP      SP 
Sbjct: 979  VKPETPPRQSHSGSISPYPKVKA----------------------QTPPGPSLSGSKSPC 1016

Query: 786  ESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSS 845
               K    +V S   +LSL   +  S   P  S+   S              +   SS  
Sbjct: 1017 PQEKSKDSLVQSCPGSLSLCAGVKSSTP-PGESYFGVSSLQLKGQSQTSPDHRSDTSSPE 1075

Query: 846  INNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQD----ISSPCLRTGISAT 901
            +  S S+   +      +    +   + P  + L + S + QD     +SP L++G+S  
Sbjct: 1076 VRQSHSESPSLQSKSQTSPKGGRSRSSSPVTE-LASRSPIRQDRGEFSASPMLKSGMSPE 1134

Query: 902  SPQSPDLKSKGTSLTAENSTGRNNADTFEDK 932
              +     S   ++ + +  G++  +T E K
Sbjct: 1135 QSRFQSDSSSYPTVDSNSLLGQSRLETAESK 1165



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 84/346 (24%), Positives = 126/346 (36%), Gaps = 66/346 (19%)

Query: 607  SSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPS-- 664
            SS C    S++ P    + ++QP A     P          S SSS   P   S  PS  
Sbjct: 782  SSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPR--------RSRSSSSPPPKQKSKTPSRQ 833

Query: 665  SPMSRKPQ-KLKSSKSLRPKESSGNSTNCQNAS----------------------SSTSG 701
            S  S  P  K+KS    R    +    N Q+ +                       S SG
Sbjct: 834  SHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSG 893

Query: 702  GSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTS----SHSIG 757
             S  + K+S+P    S S SSS      ++ S R+   + S  P PS VTS      S  
Sbjct: 894  SSPPRVKSSTPPR-QSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRS 952

Query: 758  LNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVN 817
            ++  +N  + +  R+  SG    + SP   +K  +    S   ++S  P+     + P  
Sbjct: 953  VSPCSNVESRLLPRYSHSG----SSSPDTKVKPETPPRQSHSGSIS--PYPKVKAQTP-- 1004

Query: 818  SHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQ 877
                      P   L G K  C    S  +   S P  ++    V       + T PG  
Sbjct: 1005 ----------PGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVK------SSTPPGES 1048

Query: 878  --GLMNSSLLHQDISSPCLRTGISATSPQSPDLKSKGTSLTAENST 921
              G+ +  L  Q  +SP  R+  S  SP+     S+  SL +++ T
Sbjct: 1049 YFGVSSLQLKGQSQTSPDHRSDTS--SPEVRQSHSESPSLQSKSQT 1092



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 74/315 (23%), Positives = 117/315 (37%), Gaps = 25/315 (7%)

Query: 607  SSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPS-- 664
            SS+ +SP++  V   G + N Q  +S  +D V    SR+ SSS+SSP    GL   PS  
Sbjct: 1382 SSSELSPDA--VEKAGMSSN-QSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRR 1438

Query: 665  SPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSS 724
            S     P     S +      SG+S   ++   + S G  +   +  P  +  +    S 
Sbjct: 1439 SRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSR 1498

Query: 725  SSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSP 784
            S SS  + +    C+       P    S     ++  T     +  R            P
Sbjct: 1499 SPSSPELNN---KCLT------PQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKP 1549

Query: 785  AESIKRMSVMVNSSDSTLSLGPFIHQ------SNELPVNSHGSFSHSHTPLDKLIGKKRK 838
            + S +  S   +S DS       + Q      S E+   S  S   S +     +  K +
Sbjct: 1550 SASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPR 1609

Query: 839  CSPSSSSINNSSSKPTKVA--KVPAVNNVHMKHTGTIPGAQGLMNSSLLHQDISSPCLRT 896
             +P + S ++SS +P   A   +P  +       G  P  +G  +SS        P  RT
Sbjct: 1610 AAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEG--SSSTESSPEHPPKSRT 1667

Query: 897  GISATSPQSPDLKSK 911
                 S  SP+ K+K
Sbjct: 1668 A-RRGSRSSPEPKTK 1681



 Score = 35.0 bits (79), Expect = 0.33
 Identities = 80/359 (22%), Positives = 130/359 (36%), Gaps = 42/359 (11%)

Query: 602 SPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSS 661
           SPV   S   SP  +S  +   T  A+   S +  P    +SR  + +  S  + S   +
Sbjct: 629 SPVRRRSRSRSPARRSGRSRSRT-PARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPA 687

Query: 662 VPSSPMSRKPQKLKS-SKSL--------RPKESSGNSTNCQNASSSTSGGSGKKRKNSSP 712
                 SR P++ +S S+SL        R  +  G S +     + +     + R NSSP
Sbjct: 688 RRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSP 747

Query: 713 LLVHS------SSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKAN 766
            +  S      S S SS  S + S  S R++    S  P   + T            KA 
Sbjct: 748 EMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAK 807

Query: 767 A-VNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHS 825
           +    R  +S   PP    +++  R S   +S    +  G    Q +   + S  +   S
Sbjct: 808 SRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGS---ITSPQANEQS 864

Query: 826 HTPLDKLIGKKRKCSPSS----------SSINNSSSKPTKVAKVPAVNNVHMKHTGTIPG 875
            TP      ++R C  SS          S  + S S P +V           + +   P 
Sbjct: 865 VTP------QRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPK 918

Query: 876 AQGLMN-SSLLHQDISSPCLRTGISATSPQ-----SPDLKSKGTSLTAENSTGRNNADT 928
            + +++     H   SSP      S T+P+     SP    +   L   + +G ++ DT
Sbjct: 919 VKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDT 977



 Score = 35.0 bits (79), Expect = 0.33
 Identities = 170/808 (21%), Positives = 257/808 (31%), Gaps = 162/808 (20%)

Query: 167  ERRHSSSSKPPLAVPPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPK 226
            +RR  S+S P +            S   S+   +  S RS +   LS   S S     PK
Sbjct: 738  QRRSRSNSSPEMK----------KSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPK 787

Query: 227  EKLQL---RGNTRPMHPIQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVS 283
            +K Q    R  +    P  +SR P  R  + S    K   K       S+  P       
Sbjct: 788  QKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPH------ 841

Query: 284  SLVKPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDP 343
                     P +   T P  G I +             P+ N  +     +   E   DP
Sbjct: 842  ---------PKVKSGTPPRQGSITS-------------PQANEQSVTPQRRSCFESSPDP 879

Query: 344  DIHCGVIDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPD 403
            ++        ++  C+ S   +  S T  R    R         + K K       R   
Sbjct: 880  ELKSRT---PSRHSCSGSSPPRVKSSTPPRQSPSRSSS-----PQPKVKAIISPRQRSHS 931

Query: 404  SQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQG 463
                P P R      PR S+    +P   + S   P   S     +P     P  P +Q 
Sbjct: 932  GSSSPSPSRVTSRTTPRRSRSV--SPCSNVESRLLPRY-SHSGSSSPDTKVKPETPPRQS 988

Query: 464  GSAPIDPPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFC- 522
             S  I P P  ++  PP P+   +     +E   D   +S            P   S C 
Sbjct: 989  HSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSC-----------PGSLSLCA 1037

Query: 523  -TFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRT 581
                S   G  Y+   S        L L  +   +       P   S TS    R  H  
Sbjct: 1038 GVKSSTPPGESYFGVSS--------LQLKGQSQTS-------PDHRSDTSSPEVRQSHSE 1082

Query: 582  NSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSM 641
            +    S+   S     + S+SPV    T ++  S      G   +A P     M P    
Sbjct: 1083 SPSLQSKSQTSPKGGRSRSSSPV----TELASRSPIRQDRG-EFSASPMLKSGMSP---E 1134

Query: 642  QSRQVSSSSSSPSTPS----GLSSVPSS----------------------------PMSR 669
            QSR  S SSS P+  S    G S + ++                            P+  
Sbjct: 1135 QSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQD 1194

Query: 670  KPQK---LKSSKSLRPKESSG----NSTNCQNASSSTSGGS-------GKKRKNSSPLLV 715
            +P+     K +    P+E SG      T  QN++  TS           K  + +  +L 
Sbjct: 1195 RPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILS 1254

Query: 716  HSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQS 775
            H SS     S+S     +F  +      P    T+  S S           AV V    S
Sbjct: 1255 HLSSELKEMSTS-----NFESSPEVEERPAVSLTLDQSQS------QASLEAVEVPSMAS 1303

Query: 776  GRGPPTGSPA-ESIKRMSVMVNSSDSTLSL---GPFIHQ-----SNELPVNSHGSFSHSH 826
              G P  SP  + +    +  NS  S L     GP   +     S+E+  + +G F +  
Sbjct: 1304 SWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQL 1363

Query: 827  TPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLH 886
                 L  K++    S  S +  S    + A + +  ++       +P       SS   
Sbjct: 1364 ETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSS--- 1420

Query: 887  QDISSPCLRTGISATSPQSPDLKSKGTS 914
               SSP ++ G+    P++P  +S+  S
Sbjct: 1421 -SASSPEMKDGL----PRTPSRRSRSGS 1443



 Score = 35.0 bits (79), Expect = 0.33
 Identities = 43/181 (23%), Positives = 65/181 (35%), Gaps = 28/181 (15%)

Query: 170  HSSSSKPPLAVPPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKL 229
            HS   +PP +       S   +L  +K   +S S+ SSS    S+SSSSS    S     
Sbjct: 2503 HSDVGEPPASTGAQQP-SALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSS 2561

Query: 230  QLRGNTRPMHP-IQQSRVP-----------HGRIMTPSVKVEK---------IHPKMDGT 268
               G++ P+ P +   RVP            GR   P+    K                +
Sbjct: 2562 DSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSS 2621

Query: 269  LLKSAVGPTCPATVSSLVKPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNN 328
               S+   +  ++ SS      +  S P P  P P      + LP P + +K P     +
Sbjct: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP------QALPKPASPKKPPPGERRS 2675

Query: 329  R 329
            R
Sbjct: 2676 R 2676



 Score = 34.7 bits (78), Expect = 0.43
 Identities = 67/322 (20%), Positives = 111/322 (34%), Gaps = 37/322 (11%)

Query: 648 SSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKR 707
           S SSSP      SS      S    K +  +S  PK    +    +  S ST+     +R
Sbjct: 200 SESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRR 259

Query: 708 KNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGP------------PY--PSTVTSS 753
            + S     +SSS +S S S  +        +A   P            P+  P T ++ 
Sbjct: 260 AHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQ 319

Query: 754 HSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSV-------------MVNSSDS 800
                   T + ++     D+  +      P+ S +R S                  S  
Sbjct: 320 RPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQ 379

Query: 801 TLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNS--SSKPTKVAK 858
            L+  P     ++ PVN     S +    D+   K  +  P SSS  +S  S +PTKV++
Sbjct: 380 PLATTPL----SQEPVNPPSEASPTR---DRSPPKSPEKLPQSSSSESSPPSPQPTKVSR 432

Query: 859 VPAVNNVHMKHTGTIPGAQGLMNSSLLHQDISSPCLRTGISATSPQSPDLKSKGTSLTAE 918
             A ++         PG+   ++SS   ++ S    +   S +   S  +    +  TA+
Sbjct: 433 -HASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAK 491

Query: 919 NSTGRNNADTFEDKLHLHSALW 940
               R+   T        S  W
Sbjct: 492 RGRSRSRTPTKRGHSRSRSPQW 513



 Score = 34.3 bits (77), Expect = 0.56
 Identities = 138/665 (20%), Positives = 227/665 (34%), Gaps = 106/665 (15%)

Query: 213  SASSSSSKLLKSPKEKLQLRGNTRPMHPIQQS--RVPHGRIMTPSVKVEKIHPKMDGTLL 270
            S+  SSS+L     EK  +  N     P+  +  R P  R  + S    ++   +  T  
Sbjct: 1378 SSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTP-SRERSSSASSPEMKDGLPRTPS 1436

Query: 271  KSAVGPTCPATVSSLVKPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNNRK 330
            + +   + P      ++ G   PS    +  SPG     K +P  P+  +   D+S   K
Sbjct: 1437 RRSRSGSSPG-----LRDGSGTPSRHSLSGSSPGM----KDIPRTPSRGRSECDSSPEPK 1487

Query: 331  FLNKRLSERE---FDPDIHCGVIDLDTKKPCTRS-LTCKTHSLTQ--RRAVQGRRKRFDV 384
             L +    R      P+++   +    ++  + S +  KT + T   +R+  G  +  DV
Sbjct: 1488 ALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV 1547

Query: 385  LLAEHKNKTREKELIRHPDSQ---QPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFV 441
              +    +  E +    PDS+   + P   R    + P    +   +P     S S P V
Sbjct: 1548 KPSASPQERSESD--SSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRS-RSGSSPEV 1604

Query: 442  ASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRLS----SEEGEG 497
              KP+            P  Q GS          SP P  PA     R S    S +G G
Sbjct: 1605 KDKPR----------AAPRAQSGS--------DSSPEPKAPAPRALPRRSRSGSSSKGRG 1646

Query: 498  DDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNA 557
               E S        S  HP  +     GSR                              
Sbjct: 1647 PSPEGSSST---ESSPEHPPKSRTARRGSRS----------------------------- 1674

Query: 558  QLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKS 617
                   P P T S    R     +S   ++       + + S+SP   S T   P  + 
Sbjct: 1675 ------SPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRT--PPRHRR 1726

Query: 618  VPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSS---PMSRKPQKL 674
             P+  +   A+ + S       S + R  SS  +  ++  G S  P       SR   + 
Sbjct: 1727 SPSVSSPEPAEKSRS-------SRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRR 1779

Query: 675  KSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESF 734
            + +++ R ++ SG+S +       +   S   R+       HS S +   SS + S    
Sbjct: 1780 EKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSS---- 1835

Query: 735  RKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMS-V 793
            R+       PP     + S +       +++ A    H +S    P  S   S  R S V
Sbjct: 1836 RRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPV 1895

Query: 794  MVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKP 853
                S S  S+     +S   PV+     S S TP    + ++R  S + ++   S S+ 
Sbjct: 1896 SRRRSRSRTSVTRRRSRSRASPVSRRR--SRSRTP---PVTRRRSRSRTPTTRRRSRSRT 1950

Query: 854  TKVAK 858
              V +
Sbjct: 1951 PPVTR 1955



 Score = 33.9 bits (76), Expect = 0.74
 Identities = 32/115 (27%), Positives = 40/115 (34%)

Query: 613  PNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQ 672
            P+    P         P  + A     S  S   SSSSSS S+ S  SS  SS  S    
Sbjct: 2580 PSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2639

Query: 673  KLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSS 727
               SS S  P  +          +S      G++R  S    + S   S S S S
Sbjct: 2640 SSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYS 2694



 Score = 32.0 bits (71), Expect = 2.8
 Identities = 73/372 (19%), Positives = 137/372 (36%), Gaps = 66/372 (17%)

Query: 562  KIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISP--NSKSVP 619
            + P  P++ + +  R  H T   P +  G    AA     +P  L+S  ++P  +  ++ 
Sbjct: 2328 RTPQAPASANLVGPRSAHAT--APVNIAGSRTAAAL----APASLTSARMAPALSGANLT 2381

Query: 620  AHGTTLNAQPAASGAMDP--VCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSS 677
            +    L+A    SG   P  +   +SR   S+ S     S  +  PSS M + P     S
Sbjct: 2382 SPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAP-----S 2436

Query: 678  KSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKN 737
            +SL P       +   +A S            S  L+  ++  + S S SS ++ +   +
Sbjct: 2437 QSLLPPAQDQPRSPVPSAFSD----------QSRCLIAQTTPVAGSQSLSSGAVATTTSS 2486

Query: 738  CVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNS 797
               H+G                       A  V H   G  PP  + A+    ++ +  +
Sbjct: 2487 AGDHNG------------------MLSVPAPGVPHSDVGE-PPASTGAQQPSALAALQPA 2527

Query: 798  SDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVA 857
             +          +S+    +S  S S S +            S SSSS + SSS  ++ +
Sbjct: 2528 KE---------RRSSSSSSSSSSSSSSSSS------------SSSSSSSSGSSSSDSEGS 2566

Query: 858  KVPAVNNVHMKHT-GTIPGAQGLMNSSLLHQDISSPCLRTGISATSPQSPDLKSKGTSLT 916
             +P    V +K      P  +  +      +   +   R   S++S  S    S  +S +
Sbjct: 2567 SLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSS 2626

Query: 917  AENSTGRNNADT 928
            + +S+  +++ +
Sbjct: 2627 SSSSSSSSSSSS 2638



 Score = 32.0 bits (71), Expect = 2.8
 Identities = 26/84 (30%), Positives = 32/84 (38%), Gaps = 15/84 (17%)

Query: 434  PSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDP---------PPVHESPHPPLPAT 484
            PS +KP   + PKP +P  P PPG    +    PID           PV      P P+ 
Sbjct: 2649 PSPAKPGPQALPKPASPKKP-PPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSP 2707

Query: 485  EPASRLSSEEG-----EGDDKEES 503
                  SSE G      GD +  S
Sbjct: 2708 RDQQSSSSERGSRRGQRGDSRSPS 2731



 Score = 31.2 bits (69), Expect = 4.8
 Identities = 132/661 (19%), Positives = 204/661 (30%), Gaps = 145/661 (21%)

Query: 353 DTKKPCTRSLTCKTHSLT----QRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPP 408
           DT +  +RS   KTH+            GRR   D   +E                   P
Sbjct: 273 DTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSE-------------------P 313

Query: 409 QPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHT------PSLPRP-PGCPAQ 461
                  P+ P T+ +   +P+     + K   A++P P        P  P P P    +
Sbjct: 314 GTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAER 373

Query: 462 QGGS-----------APIDPPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCH 510
            GGS            P++PP          P   P     S   E         K+  H
Sbjct: 374 HGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRH 433

Query: 511 YSG--HHPQPA---------------------------SFCTFGSRQIGRGYYVFDSRWN 541
            S     P+PA                           S     SR++GR      ++  
Sbjct: 434 ASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRG 493

Query: 542 RLRC----------ALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGV 591
           R R           + +    +  +AQ W +           S + P  + S  T + G 
Sbjct: 494 RSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGR 553

Query: 592 SYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSS 651
           S  A    S             +S+S    G + +  PA  G        +SR  +   S
Sbjct: 554 SRSARRGRS-------------HSRSPATRGRSRSRTPARRG------RSRSRTPARRRS 594

Query: 652 SPSTPSGLSSVPSSP------MSRKPQKLKS---------SKSLRPKESSGNSTNCQNAS 696
              TP+   S   +P       SR P + +S         S+S  P   SG S +   A 
Sbjct: 595 RSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPAR 654

Query: 697 SSTSGGSGKKRKNSSPLLVHSSSSSSS----------SSSSSHSMESFRKNCVAHSGPPY 746
              S      R+  S     +  S  S          S S +      R   +   G  +
Sbjct: 655 RGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSH 714

Query: 747 PSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKR---MSVMVNSSDSTLS 803
             T       G +      +  + R  +S   P       S +R   +S   + + S LS
Sbjct: 715 SRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLS 774

Query: 804 LGPFIHQSNELPVNS-----HGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAK 858
           L   +  S+  P          S S S  P      K +  +P   S ++SS  P + +K
Sbjct: 775 LRRSLSGSSPCPKQKSQTPPRRSRSGSSQP------KAKSRTPPRRSRSSSSPPPKQKSK 828

Query: 859 VP-----AVNNVHMKHTGTIPGAQGLMNSSLLHQDISSPCLRTGISATSPQSPDLKSKGT 913
            P     + ++ H K     P  QG + S   ++   +P  R+     S   P+LKS+  
Sbjct: 829 TPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFE--SSPDPELKSRTP 886

Query: 914 S 914
           S
Sbjct: 887 S 887



 Score = 31.2 bits (69), Expect = 4.8
 Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 6/89 (6%)

Query: 159  PQAFQSHYERRHSSSSKPPLAVPPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSS 218
            P+   +  +RR SSSS        +S  S   S S S   S+S S+ SSS    S+SSS 
Sbjct: 2596 PEPTPAKRKRRSSSSSSS------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP 2649

Query: 219  SKLLKSPKEKLQLRGNTRPMHPIQQSRVP 247
            S     P+   +     +P    ++SR P
Sbjct: 2650 SPAKPGPQALPKPASPKKPPPGERRSRSP 2678



 Score = 30.8 bits (68), Expect = 6.2
 Identities = 17/76 (22%), Positives = 36/76 (47%), Gaps = 4/76 (5%)

Query: 16   AAAAAGGAAAAAARQQQQQQQQQQPPP---PQPQRQQHPPPPPRRTR-PEDGGPGAASTS 71
            +++++  ++++++          +P P   P+P   + PPP  RR+R P         + 
Sbjct: 2630 SSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSR 2689

Query: 72   AAAMATVGERRPLPSP 87
            + + + V  RRP P P
Sbjct: 2690 SLSYSPVERRRPSPQP 2705


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 71/289 (24%), Positives = 109/289 (37%), Gaps = 18/289 (6%)

Query: 640 SMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSST 699
           S  S   S S SS S  S  S   SS  S       SS S    +SS +S +  ++S S 
Sbjct: 571 SSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSE 630

Query: 700 SGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLN 759
           S  S    K+ S     S S+SS SS +S S +S   +  + S     S+ +SS S   N
Sbjct: 631 SDSSDSDSKSDS-----SDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685

Query: 760 CVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSH 819
              +  ++ +    +S     +     S    S   NSSDS          SN    +  
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSD--------SSNSSDSSDS 737

Query: 820 GSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGL 879
            + S S    D         S  SS+ ++SS          + N+     +     +   
Sbjct: 738 SNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797

Query: 880 MNSSLLHQDISSPCLRTGISATSPQSPDLKSKGTSLTAENSTGRNNADT 928
            NSS      SS    +  S+ S  S    S  +S ++++S   N++D+
Sbjct: 798 SNSS-----DSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 71/308 (23%), Positives = 121/308 (39%), Gaps = 15/308 (4%)

Query: 626  NAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKES 685
            N+  + S + +   S  S   S SS S  + +   S  SS  S       SS S    +S
Sbjct: 720  NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS 779

Query: 686  SGNS--TNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSG 743
            S +S   +  N+S S+   +     NSS     S SS S SS+SS S  S   +  ++S 
Sbjct: 780  SNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS 839

Query: 744  PPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLS 803
                S+ +S  S   +  +N++++ N             S +      +   NSSDS+ S
Sbjct: 840  DSSDSSDSSDGSDSDS--SNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDS 897

Query: 804  LGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVN 863
                   S++   +S  S S + +            S SS+S +NS+S  +  +   + +
Sbjct: 898  SNSSDSDSSDSSNSSDSSDSSNSS----------DSSESSNSSDNSNSSDSSNSS-DSSD 946

Query: 864  NVHMKHTGTIPGAQGLMNSSLLHQDISSPCLRTGISATSPQSPDLKSKGTSLTAENSTGR 923
            +    ++     +    NSS      SS    +  S+ S  S D      S  + NS+  
Sbjct: 947  SSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDS 1006

Query: 924  NNADTFED 931
            +++    D
Sbjct: 1007 SDSSDSSD 1014



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 81/364 (22%), Positives = 133/364 (36%), Gaps = 8/364 (2%)

Query: 568  STTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNA 627
            S+ S  S+     +NS  +S    S  ++ + ++S    SS     +  S  +  +  + 
Sbjct: 749  SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808

Query: 628  QPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSG 687
               +S + D   S  S   +SS SS S+ S  SS  S           +         S 
Sbjct: 809  SSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS 868

Query: 688  NSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYP 747
            +S++  N+S S+      +  NSS     S+SS S SS SS+S +S   +  + S     
Sbjct: 869  DSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSN 928

Query: 748  STVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPF 807
            S+  S+ S   N   +  ++     D S     + S   S    S   NSSDS+ S    
Sbjct: 929  SSDNSNSSDSSNSSDSSDSS-----DSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNS- 982

Query: 808  IHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHM 867
               S+    +     S S    D         S +SS  +NSS          + ++   
Sbjct: 983  SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042

Query: 868  KHTGTIPGAQGLMNSSLLHQDISSPCLRTGISATSPQSPDLKSKGTSLTAENSTGRNNAD 927
              +     +    NSS      SS    +  S+ S  S D      S  + NS+  +++ 
Sbjct: 1043 SDSSDSSDSSDSSNSS--DSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSS 1100

Query: 928  TFED 931
               D
Sbjct: 1101 DSSD 1104



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 73/324 (22%), Positives = 114/324 (35%), Gaps = 4/324 (1%)

Query: 607 SSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSP 666
           SS   S +S S  +  +  +    +S + D   S  S   S SS S S  S   S  S  
Sbjct: 577 SSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDS 636

Query: 667 MSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSS-SS 725
            S+      +S        S +S+N  N+S S+         +SS     S SS SS SS
Sbjct: 637 DSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS 696

Query: 726 SSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNC--VTNKANAVNVRHDQSGRGPPTGS 783
           +SS S +S   +    S     S   SS S   N    ++ +N+ +             S
Sbjct: 697 NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS 756

Query: 784 PAESIKRMSVMVNSSDST-LSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPS 842
            +      S   +SSDS+  S       SN+   +S  S S + +              S
Sbjct: 757 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS 816

Query: 843 SSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQDISSPCLRTGISATS 902
            S  +NSS          + N+     +          +S+      SS    +  S+ S
Sbjct: 817 DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS 876

Query: 903 PQSPDLKSKGTSLTAENSTGRNNA 926
             S D      S  + +S+  +N+
Sbjct: 877 SDSSDSSDSNESSNSSDSSDSSNS 900



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 66/297 (22%), Positives = 114/297 (38%), Gaps = 11/297 (3%)

Query: 632 SGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTN 691
           S   D   S  S    SS+SS S+ S  SS  S        K  SSKS    ES  + ++
Sbjct: 582 SSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS----ESDSSDSD 637

Query: 692 CQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVT 751
            ++ SS ++        +SS     S+SS+SS SS S        +  + +      +  
Sbjct: 638 SKSDSSDSNSSDSSDNSDSSD---SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSD 694

Query: 752 SSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQS 811
           SS+S   +  ++ +++ +     S     + S + +    S   NSSDS+ S       S
Sbjct: 695 SSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDS----SDSS 750

Query: 812 NELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHTG 871
           N    +     S+S    D         S +SS  N+SS+         + ++ +   + 
Sbjct: 751 NSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSS 810

Query: 872 TIPGAQGLMNSSLLHQDISSPCLRTGISATSPQSPDLKSKGTSLTAENSTGRNNADT 928
               +    +S+      SS    +  S+ S  S D      S ++  S   N++D+
Sbjct: 811 DSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDS 867



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 60/256 (23%), Positives = 101/256 (39%), Gaps = 8/256 (3%)

Query: 676 SSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFR 735
           S+      +S+GN  N  + +  +  G GK   + S     S+SS SS SS S S +S  
Sbjct: 517 STSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNS 576

Query: 736 KNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMV 795
            +    S      +  S  S   N  ++ ++  +   D S     + S ++S K  S   
Sbjct: 577 SSDSDSSDSDSSDSSDSDSSDSSN--SSDSSDSSDSSDSSDSSDSSDSKSDSSKSES--- 631

Query: 796 NSSDSTLSLGPFIHQSNELPVNSHGS-FSHSHTPLDKLIGKKRKCSPSSSSINNS--SSK 852
           +SSDS          S++   NS  S  S+S    D         S SSS  +NS  SS 
Sbjct: 632 DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691

Query: 853 PTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQDISSPCLRTGISATSPQSPDLKSKG 912
            +  +     ++           +    NS+    D S+    +  S +S  S    S  
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSN 751

Query: 913 TSLTAENSTGRNNADT 928
           +S ++++S   N++D+
Sbjct: 752 SSDSSDSSDSSNSSDS 767



 Score = 39.3 bits (90), Expect = 0.018
 Identities = 44/161 (27%), Positives = 66/161 (40%), Gaps = 4/161 (2%)

Query: 568  STTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNA 627
            S+ S  S+     +NS  +S    S  ++ +  +S    SS     +  S  ++ +  + 
Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1062

Query: 628  QPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSG 687
               +S + D   S  S   S SS S  + +   S  SS  S       SS S    +SS 
Sbjct: 1063 SSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1122

Query: 688  NSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSS 728
            +S +  ++ SS S  S     NSS     S SS SS SS S
Sbjct: 1123 SSDSSDSSDSSDSSDSS----NSSDSSDSSESSDSSDSSDS 1159


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 76/317 (23%), Positives = 119/317 (37%), Gaps = 44/317 (13%)

Query: 613  PNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPS--TPSGLSSVPSSPMSRK 670
            P S  +  HG +  +            S+ +  +S  + SPS   P G S   +SPM   
Sbjct: 1153 PGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPV 1212

Query: 671  PQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHS 730
            P    SSK+  P  S    ++    SSS+   S     +S  L   +  SS+S ++SS S
Sbjct: 1213 PGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSS 1272

Query: 731  MESFRKNCVA---HSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAES 787
              S   +  +     G     + + +    L  V +K     ++H     GP    P + 
Sbjct: 1273 FSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDK-----LKHGVVTSGPGGEDPLDG 1327

Query: 788  IKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSIN 847
              +M V  NSS          H  +     S G F       DK    K K S S SS++
Sbjct: 1328 --QMGVSTNSSS---------HPMSSKHNMSGGEFQGKREKSDK---DKSKVSTSGSSVD 1373

Query: 848  NSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQDISSPCLRTGISATSPQSPD 907
              SSK T  +K     NV         G+ G+    +   D  SP ++  ++   P    
Sbjct: 1374 --SSKKTSESK-----NV---------GSTGVAKIIISKHDGGSPSIKAKVTLQKPG--- 1414

Query: 908  LKSKGTSLTAENSTGRN 924
             +S G  L  + ++ +N
Sbjct: 1415 -ESSGEGLRPQMASSKN 1430



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 75/291 (25%), Positives = 116/291 (39%), Gaps = 18/291 (6%)

Query: 579  HRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPV 638
            +R  + PTS  G     +A  S +P  +++  I   +  +P  GT +  +P++       
Sbjct: 1028 NRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPK-GTVMVGKPSSHSQYTSS 1086

Query: 639  CSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSK-SLRPKESSGNSTNCQNASS 697
             S+ S    S  S  S+ S  +S      S K +   SSK S     S G+S + Q+ +S
Sbjct: 1087 GSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNS 1146

Query: 698  STSGGSGKKRKNSSPLLVHSSSSSSSSSS-------SSHSMESFRKNCV--AHSGPPYPS 748
            S SGG    +  SSP+  H  SS SSS+        SS    S  K  +  +HS PP  S
Sbjct: 1147 SQSGG----KPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGS 1202

Query: 749  TVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFI 808
               +S    +      + A +     SG    +G+ + S  + S  + SS S     P  
Sbjct: 1203 DKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTP-- 1260

Query: 809  HQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKV 859
              S+     S  SFS S + +     +       S S N   S    + K+
Sbjct: 1261 -PSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKL 1310


>gi|5174545 myocyte enhancer factor 2D [Homo sapiens]
          Length = 521

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 33/96 (34%), Positives = 43/96 (44%), Gaps = 4/96 (4%)

Query: 402 PDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQ 461
           P  QQPPQP + P P  P+  Q+P Q    ++P      +   P PH  +       P  
Sbjct: 378 PPQQQPPQP-QQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTVTTHPHI 436

Query: 462 QGGSAPIDPPPVHESPHPPLPATEPASRLSSEEGEG 497
              S P+ P     SP PP PA  PA+R   E G+G
Sbjct: 437 SIKSEPVSPSR-ERSPAPPPPAVFPAAR--PEPGDG 469



 Score = 38.5 bits (88), Expect = 0.030
 Identities = 19/46 (41%), Positives = 27/46 (58%), Gaps = 2/46 (4%)

Query: 16  AAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRPE 61
           A ++ GG +       QQ QQ QQP  PQP +QQ  PP P++ +P+
Sbjct: 349 AFSSPGGLSLGNVTAWQQPQQPQQPQQPQPPQQQ--PPQPQQPQPQ 392



 Score = 35.0 bits (79), Expect = 0.33
 Identities = 19/45 (42%), Positives = 22/45 (48%), Gaps = 8/45 (17%)

Query: 21  GGAAAAAARQQQQQQQQQQPPP--------PQPQRQQHPPPPPRR 57
           G   A    QQ QQ QQ QPP         PQPQ+ Q P  PP++
Sbjct: 359 GNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQ 403



 Score = 33.5 bits (75), Expect = 0.96
 Identities = 42/168 (25%), Positives = 67/168 (39%), Gaps = 28/168 (16%)

Query: 621 HGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQK------- 673
           +G+T+ A   A     PV +  S Q S+ S S  TPS ++S  + P    PQ+       
Sbjct: 131 YGSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLSPQQPALQRNS 190

Query: 674 LKSSKSLRPKESS---GNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHS 730
           +      RP  +    G   N  N +  +  G+G     +SP L+  ++ +         
Sbjct: 191 VSPGLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLLPVANGN--------- 241

Query: 731 MESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRG 778
             S  K   A S PP       +HS  L   + K + + V   Q+G+G
Sbjct: 242 --SLNKVIPAKSPPP------PTHSTQLGAPSRKPD-LRVITSQAGKG 280


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 62/257 (24%), Positives = 89/257 (34%), Gaps = 40/257 (15%)

Query: 416  PAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPP-VH 474
            P PP     PH + H   P          P+PH      PP  P  + G +P DPPP + 
Sbjct: 992  PLPPAHHHPPHHHHHHAPP----------PQPHHHHA-HPPHPPEMETGGSPDDPPPRLA 1040

Query: 475  ESPHPPL-------PATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSR 527
              P P L       P+  P +   S  G       S +     Y    P+ AS   +   
Sbjct: 1041 LGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPA 1100

Query: 528  QIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTR------IPHRT 581
            + GRG           +  L    +     Q    +PP PS TSP S +       P   
Sbjct: 1101 RSGRG----------RKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEK 1150

Query: 582  NSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSM 641
            NS+P     +   + ++   S    S+    P        G    + P+ + AM PV   
Sbjct: 1151 NSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPV--- 1207

Query: 642  QSRQVSSSSSSPSTPSG 658
                  S   +P++PSG
Sbjct: 1208 --PPSPSPVPTPASPSG 1222



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 85/392 (21%), Positives = 119/392 (30%), Gaps = 67/392 (17%)

Query: 405  QQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGG 464
            Q PP+P    + APP T    H +PH       + + AS P P    L    G  +Q+  
Sbjct: 1375 QPPPRPPSPRYEAPPPTPH--HHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEK- 1431

Query: 465  SAPIDPPPVHES------PHPP--------LPATEPASRLSSEEGEGDDKEESVEKLDCH 510
            S P  PP    S      P  P        L    PA      +       E  E+L  H
Sbjct: 1432 SLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLH 1491

Query: 511  YSG-HHPQPASFCTFGS---RQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPV 566
                 + QP +  T G     + G G      R +      +    +     L    PP 
Sbjct: 1492 VRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPA 1551

Query: 567  PSTT--------------------------SPISTRIPHRTNSVPTSQCGVSYLAAATVS 600
            PS                            SP++   PH     P     +  +    V+
Sbjct: 1552 PSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVA 1611

Query: 601  TSPVLLSSTCISPNSKSVPAHGTTLNAQ-----PAASGAMDPVCSMQSRQVSSSSSSPST 655
             +P  L ST  S  S        T  A      P   G   P     +         P T
Sbjct: 1612 AAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGT 1671

Query: 656  PSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLV 715
             SG+  V S   S  P +  SS       S+ +S + +   S+  GG       S P L+
Sbjct: 1672 DSGIEEVDSRSSSDHPLETISS------ASTLSSLSAEGGGSAGGGGGAGAGVASGPELL 1725

Query: 716  HSSSSSSSSSSSSHSMESFRKNCVAHSGPPYP 747
             +  +     +   S         +  GPPYP
Sbjct: 1726 DTYVAYLDGQAFGGS---------STPGPPYP 1748



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 33/114 (28%), Positives = 41/114 (35%), Gaps = 20/114 (17%)

Query: 402  PDSQQPPQPLRDPHPAPPRTSQEP---HQNPHGVIPSESKPFVASKPKPHTPSLPRPPG- 457
            PD+  P  PL  P   PP  +  P         +   +S+    ++     P  P PPG 
Sbjct: 1593 PDTPAPATPL--PPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGP 1650

Query: 458  -CPAQQGGSAPI---DPPP----------VHESPHPPLPATEPASRLSSEEGEG 497
              PA    +AP    DPPP             S   PL     AS LSS   EG
Sbjct: 1651 PAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEG 1704



 Score = 32.0 bits (71), Expect = 2.8
 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 6/79 (7%)

Query: 13   PRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRPEDGGPGAASTSA 72
            P RAA+AA    A + R ++    +Q     +PQ+    PP P  T P      A+    
Sbjct: 1088 PPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSP------ASPQPP 1141

Query: 73   AAMATVGERRPLPSPEVML 91
             A+A   E+  +P P +++
Sbjct: 1142 PAVAAPSEKNSIPIPTIII 1160



 Score = 31.6 bits (70), Expect = 3.7
 Identities = 25/81 (30%), Positives = 35/81 (43%), Gaps = 3/81 (3%)

Query: 172 SSSKPPLAVPPTSVFSFFPSLSKSKGGSASGSNRSS--SGGVLSASSSSSKLLKSPKEKL 229
           ++S   +A+P   VFS   + S    G  SGS   S  S      SS + +   SP+   
Sbjct: 437 ANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPR-GA 495

Query: 230 QLRGNTRPMHPIQQSRVPHGR 250
           + R  +R  HP    R P GR
Sbjct: 496 RARSPSRGRHPEDAKRQPRGR 516


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 144/731 (19%), Positives = 230/731 (31%), Gaps = 135/731 (18%)

Query: 13  PRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRPEDGGPGAASTSA 72
           PRR ++        +  +  + + + + P P P++++  P  P  +          +TS 
Sbjct: 182 PRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATST 241

Query: 73  AAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNREVMGLCRED 132
           + +  V +  P+P P               K P  +     E  KE  + R      +  
Sbjct: 242 SDILKVPKPEPIPEP---------------KEPSPEKNSKKEKEKEKTRPRS-RSRSKSR 285

Query: 133 MPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPPLAVPPTSVFSFFPSL 192
                  P+H           ++   P+   S   R       PP  +PP       P  
Sbjct: 286 SRTRSRSPSHTRPRRRH-RSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPP-------PPR 337

Query: 193 SKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMH---------PIQQ 243
            +          RSS+    S+SSSSS   +SP +K   R ++ P           P ++
Sbjct: 338 HRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRR 397

Query: 244 SRVPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVK-PGLNCPSIPKPTLPS 302
              P      P        P+      KS V  +   T   + K  G      P P  P 
Sbjct: 398 RHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPA-PK 456

Query: 303 PGQI--------LNGKGLPAPPTLEKKPEDNSNNRKFLNKRLS-----EREFDPDIHCGV 349
           P ++          GK   A    +++     N +   +   S     ER     +  G 
Sbjct: 457 PRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGE 516

Query: 350 IDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQ 409
           +    +   +RS +       +  + +GRR+R     +     TR +   R P    PP+
Sbjct: 517 VGRRRRHSPSRSASPSPRKRQKETSPRGRRRR-----SPSPPPTRRR---RSPSPAPPPR 568

Query: 410 PLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPID 469
             R P P P R +  P        P    P +  +  P  P   R    P      A   
Sbjct: 569 RRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPS 628

Query: 470 PPPVHESPH--PPLPATEPASR-----LSSEEGEGDDKEESVEKLDCHYSGHHPQPASFC 522
           PPP     H  PP   + P ++     LSS+  +G     S  +         PQP    
Sbjct: 629 PPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTRE------ARSPQPN--- 679

Query: 523 TFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTN 582
                                                 K+  P P        R P  ++
Sbjct: 680 --------------------------------------KRHSPSP------RPRAPQTSS 695

Query: 583 SVPTSQCGVSYLAAATVSTSPVLLSSTCIS--PNSKSVPAHGTTLNAQPAASGAMDPVCS 640
           S P  + G S       S SP       +S  P  K +         + AAS +   V  
Sbjct: 696 SPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKI---------KKAASPSPQSV-- 744

Query: 641 MQSRQVSSS---SSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASS 697
              R+VSSS   S SP   +     P SP+  +      S ++  K++   + +     +
Sbjct: 745 ---RRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRN 801

Query: 698 STSGGSGKKRK 708
           S   G GKK+K
Sbjct: 802 SDQEGGGKKKK 812



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 114/534 (21%), Positives = 175/534 (32%), Gaps = 87/534 (16%)

Query: 4   RAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRPEDG 63
           R+   VR   R +A+ +G ++++++       + + PP   P+R   PP   RR  P   
Sbjct: 340 RSRSPVRRRRRSSASLSGSSSSSSS------SRSRSPPKKPPKRTSSPPRKTRRLSPSAS 393

Query: 64  GPGAASTSAAAMATVGERRPLPSPEVM-LGQSWNLWVEASKLPGK----DGTELDESFKE 118
            P      +       + R  P+P+     +   + V   +  GK     GTE  ES   
Sbjct: 394 PPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSP 453

Query: 119 FGKNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPPL 178
             K R+V  L   +    G   A D           +  + Q  QS  +   SSSS+   
Sbjct: 454 APKPRKVE-LSESEEDKGGKMAAADSVQQ------RRQYRRQNQQSSSDSGSSSSSEDER 506

Query: 179 AVPPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEK---------L 229
                      P  S  K G      R S     S S    +   SP+ +          
Sbjct: 507 -----------PKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPT 555

Query: 230 QLRGNTRPMHPIQQSRVP----HGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSL 285
           + R +  P  P ++ R P      R  +P  +     P+     ++    P+ P    + 
Sbjct: 556 RRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTA 615

Query: 286 VKPGLNCPSIPKPTLPSPGQILNGKGLP------APPTLEKKPEDNSNNRKFLNKRLSER 339
             P    P   +   PSP         P      +P T  + P  +S +RK  +   S R
Sbjct: 616 SPP----PPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTR 671

Query: 340 EFDPDIHCGVIDLDTKKPCTRSLTCKTHSLTQR-RAVQGRRKRFDVLLAEHKNKTREKEL 398
           E              + P       K HS + R RA Q       V      +       
Sbjct: 672 E-------------ARSPQPN----KRHSPSPRPRAPQTSSSPPPVRRGASSS------- 707

Query: 399 IRHPDSQQPPQPLRDP------HPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSL 452
              P  +Q P P   P       P P +  +    +P  V    S   V+  P+P     
Sbjct: 708 ---PQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKP 764

Query: 453 PRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEK 506
           P PP     Q  S    P    +    P P+  P  R S +EG G  K++  +K
Sbjct: 765 PAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP-PRNSDQEGGGKKKKKKKDK 817



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 74/332 (22%), Positives = 112/332 (33%), Gaps = 75/332 (22%)

Query: 194 KSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSRVPHGRIMT 253
           + K  S     RS S     + S S +   SP  + + R ++R      +SR P     +
Sbjct: 157 EEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSP-----S 211

Query: 254 PSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTLPSPGQILNGKGLP 313
           P+ + ++  P++    +K        AT +S +        +PKP              P
Sbjct: 212 PAPEKKEKTPELPEPSVKVKEPSVQEATSTSDIL------KVPKPE-------------P 252

Query: 314 APPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSLTQRR 373
            P   E  PE NS   K                    + +  +P +RS + K+ S T+ R
Sbjct: 253 IPEPKEPSPEKNSKKEK--------------------EKEKTRPRSRSRS-KSRSRTRSR 291

Query: 374 AVQGRRKRFDVLLAEHKNKTREKELIRHPDSQ-------------QPPQPLRDPHPAPPR 420
           +    R R       H++++R     R P  +              PP P      +P R
Sbjct: 292 SPSHTRPR-----RRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVR 346

Query: 421 TSQEPHQNPHGVIPSESKPFVAS---KPKPHTPSLPR------PPGCPAQQ--GGSAPID 469
             +    +  G   S S     S   KP   T S PR      P   P ++    S P  
Sbjct: 347 RRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPAT 406

Query: 470 PPP-VHESPHPPLPATEPASRLSSEEGEGDDK 500
           PPP    SP P        SR+S   G    K
Sbjct: 407 PPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGK 438


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 67/300 (22%), Positives = 92/300 (30%), Gaps = 68/300 (22%)

Query: 402 PDSQQPPQPLRDPHPAP------PRTSQEP----HQNPHGVIPSESKPFVASKPKPHTPS 451
           P + + P P     PAP      P T +EP     + P    P E  P    +P P TP 
Sbjct: 272 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK 331

Query: 452 LPRP------PGCPAQQGGSAPIDPPPVHESPHPPLPAT--EPASRLSSEEGEGDDKEES 503
            P P      P  P +   +AP  P P   +P  P P T  EPA   + E      KE  
Sbjct: 332 EPAPTTKEPAPTTPKEPAPTAPKKPAPT--TPKEPAPTTPKEPAPTTTKEPSPTTPKE-- 387

Query: 504 VEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKI 563
                         PA   T  +                          K       K  
Sbjct: 388 --------------PAPTTTKSAP----------------------TTTKEPAPTTTKSA 411

Query: 564 PPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT 623
           P  P   SP +T+ P  T              A T    P   +    +P +   PA  T
Sbjct: 412 PTTPKEPSPTTTKEPAPTTPKE---------PAPTTPKKPAPTTPKEPAPTTPKEPAPTT 462

Query: 624 TLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS-SVPSSPMSRKPQKLKSSKSLRP 682
           T    P       P    ++   +    +P+TP  L+ + P  P    P++L  +    P
Sbjct: 463 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 522



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 59/250 (23%), Positives = 84/250 (33%), Gaps = 17/250 (6%)

Query: 249 GRIMTPSVK----VEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTLPSPG 304
           G+  T S K    +EK   K      K    PT P   ++   P L  P  P PT P   
Sbjct: 166 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT-PKAETTTKGPALTTPKEPTPTTPKEP 224

Query: 305 QILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTC 364
                K  P P T++  P           K       +P          TK+P   +   
Sbjct: 225 ASTTPKE-PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP------APTTTKEPAPTTPKE 277

Query: 365 KTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQE 424
              + T+  A     K       E    T +K     P    P  P ++P P  P+    
Sbjct: 278 PAPTTTKEPAPT-TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-KEPTPTTPKEPAP 335

Query: 425 PHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPAT 484
             + P    P E  P    KP P TP  P P   P +   +   +P P   +P  P P T
Sbjct: 336 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKEPSPT--TPKEPAPTT 392

Query: 485 EPASRLSSEE 494
             ++  +++E
Sbjct: 393 TKSAPTTTKE 402



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 105/516 (20%), Positives = 171/516 (33%), Gaps = 56/516 (10%)

Query: 213 SASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKS 272
           +A ++  KL  +  EKL      +P     +   P     T   +     P+        
Sbjct: 482 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-----TTPEEPTPTTPEEPAPTTPK 536

Query: 273 AVGPTCPATVSSLV--KPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNNRK 330
           A  P  P   +     +P    P  P PT P        KG  AP TL K+P   +    
Sbjct: 537 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT-APTTL-KEPAPTTP--- 591

Query: 331 FLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTC-KTHSLTQRRAVQGRRKRFDVLLAEH 389
              K+ + +E  P          TK+P   S TC K    T +       K       + 
Sbjct: 592 ---KKPAPKELAPTT--------TKEPT--STTCDKPAPTTPKGTAPTTPKEPAPTTPKE 638

Query: 390 KNKTREKELIRHPDSQQPPQPLRDPHPAP----PRTSQEP----HQNPHGVIPSESKPFV 441
              T  K     P + + P P     PAP    P T++ P       P    P E+ P  
Sbjct: 639 PAPTTPKGTA--PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 696

Query: 442 ASKPKPHTPSLPRP----PGCPAQQGGSAPI---DPPPVHESPHPPLPATEPASRLSSEE 494
             +P P TP  P P       P     S P    +P  +H+SP    P  E ++  + + 
Sbjct: 697 PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP--ELSAEPTPKA 754

Query: 495 GEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWN---RLRCALNLMV 551
            E   KE  V       +    +P    T   +   R             ++        
Sbjct: 755 LENSPKEPGVPTTKTPAA---TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTT 811

Query: 552 EKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCI 611
           EK   +++      V STT+  +T     T    T    V+       +T  +       
Sbjct: 812 EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETA 871

Query: 612 SPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSR---QVSSSSSSPSTPSGLSSVPS-SPM 667
            P  ++  +  TT   Q        P  + + +   +V    ++P+     S++P  +P 
Sbjct: 872 KPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 931

Query: 668 SRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGS 703
           SR  + +  + + RP ++  +     N  S  +GG+
Sbjct: 932 SRIAEAMLQT-TTRPNQTPNSKLVEVNPKSEDAGGA 966



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 61/284 (21%), Positives = 92/284 (32%), Gaps = 48/284 (16%)

Query: 410 PLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGC--PA-QQGGSA 466
           P     PAP  T   P        P E  P    +P P TP  P P     PA     SA
Sbjct: 241 PTTPKEPAPTTTKSAP------TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 294

Query: 467 PIDP-PPVHESPHPPLPAT--EPASRLSSEEGEGDDKEES-VEKLDCHYSGHHPQPASFC 522
           P  P  P   +P  P P T  EPA     E      KE +   K     +   P P +  
Sbjct: 295 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA-- 352

Query: 523 TFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTN 582
                                        +K       +  P  P   +P +T+ P  T 
Sbjct: 353 ----------------------------PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT- 383

Query: 583 SVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQ 642
             P      +  +A T +  P   ++T  +P +   P+  TT   +PA +   +P  +  
Sbjct: 384 -TPKEPAPTTTKSAPTTTKEPA-PTTTKSAPTTPKEPSPTTT--KEPAPTTPKEPAPTTP 439

Query: 643 SRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESS 686
            +   ++   P+  +     P++     P   K      PKE++
Sbjct: 440 KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 483



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 108/526 (20%), Positives = 153/526 (29%), Gaps = 89/526 (16%)

Query: 268 TLLKSAVGPTCPATVSSLV--KPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDN 325
           T  KSA  PT P   +     KP    P  P PT P        K  PAP T E  P   
Sbjct: 289 TTTKSA--PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE-PAPTTKEPAPTTP 345

Query: 326 SNNRKFLNKR---LSEREFDPDIHCGVIDLDTKKPCTRS------LTCKTHSLTQRRAVQ 376
                   K+    + +E  P          TK+P   +       T K+   T +    
Sbjct: 346 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 405

Query: 377 GRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSE 436
              K       E    T ++     P    P  P + P P  P+        P    P E
Sbjct: 406 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP-KKPAPTTPK-------EPAPTTPKE 457

Query: 437 SKPFVASKPKPHTPSLPRP---------------PGCPAQQGGSAPIDPPPVHE------ 475
             P    KP P TP  P P               P  P +   + P  P P         
Sbjct: 458 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 517

Query: 476 SPHPPLPAT--EPASRLSSEEGEGDDKEES--VEKLDCHYSGHHPQPASFC-TFGSRQIG 530
           +P  P P T  EPA            KE +    K     +   P P +   T  +   G
Sbjct: 518 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 577

Query: 531 RGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNS---VPTS 587
                                 K       KK  P P   +P +T+ P  T      PT+
Sbjct: 578 TAPTTL----------------KEPAPTTPKK--PAPKELAPTTTKEPTSTTCDKPAPTT 619

Query: 588 QCGVSYLA----AATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQS 643
             G +       A T    P   +    +P +   PA  T     P     + P  +   
Sbjct: 620 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE---LAPTTTKGP 676

Query: 644 RQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGS 703
              +S   +P+TP    + P++P    P   K      P+     ++     +++     
Sbjct: 677 TSTTSDKPAPTTPK--ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT----- 729

Query: 704 GKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPST 749
                   P  +H S   S+   S+       +N     G P   T
Sbjct: 730 ------KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT 769



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 7/114 (6%)

Query: 581 TNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSV----PAHGTTLNAQPAASGAMD 636
           T +  TS  G     +A  + S    S+  ++P SK +    P   TT    PA +   +
Sbjct: 157 TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG-PALTTPKE 215

Query: 637 PVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNST 690
           P  +      S++   P TP+ + S P++P    P   KS+ +  PKE +  +T
Sbjct: 216 PTPTTPKEPASTTPKEP-TPTTIKSAPTTPKEPAPTTTKSAPT-TPKEPAPTTT 267



 Score = 32.0 bits (71), Expect = 2.8
 Identities = 27/151 (17%), Positives = 51/151 (33%), Gaps = 9/151 (5%)

Query: 564 PPVPSTTSPISTR--IPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAH 621
           P  P   +P +T+   P  T S PT+             T+P   + T     + + P  
Sbjct: 272 PTTPKEPAPTTTKEPAPTTTKSAPTTP-------KEPAPTTPKKPAPTTPKEPAPTTPKE 324

Query: 622 GTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLR 681
            T    +  A    +P  +       ++   P+  +     P++P    P   K      
Sbjct: 325 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 384

Query: 682 PKESSGNSTNCQNASSSTSGGSGKKRKNSSP 712
           PKE +  +T     ++     +  K   ++P
Sbjct: 385 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 415


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 67/300 (22%), Positives = 92/300 (30%), Gaps = 68/300 (22%)

Query: 402 PDSQQPPQPLRDPHPAP------PRTSQEP----HQNPHGVIPSESKPFVASKPKPHTPS 451
           P + + P P     PAP      P T +EP     + P    P E  P    +P P TP 
Sbjct: 313 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK 372

Query: 452 LPRP------PGCPAQQGGSAPIDPPPVHESPHPPLPAT--EPASRLSSEEGEGDDKEES 503
            P P      P  P +   +AP  P P   +P  P P T  EPA   + E      KE  
Sbjct: 373 EPAPTTKEPAPTTPKEPAPTAPKKPAPT--TPKEPAPTTPKEPAPTTTKEPSPTTPKE-- 428

Query: 504 VEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKI 563
                         PA   T  +                          K       K  
Sbjct: 429 --------------PAPTTTKSAP----------------------TTTKEPAPTTTKSA 452

Query: 564 PPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT 623
           P  P   SP +T+ P  T              A T    P   +    +P +   PA  T
Sbjct: 453 PTTPKEPSPTTTKEPAPTTPKE---------PAPTTPKKPAPTTPKEPAPTTPKEPAPTT 503

Query: 624 TLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS-SVPSSPMSRKPQKLKSSKSLRP 682
           T    P       P    ++   +    +P+TP  L+ + P  P    P++L  +    P
Sbjct: 504 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 563



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 59/250 (23%), Positives = 84/250 (33%), Gaps = 17/250 (6%)

Query: 249 GRIMTPSVK----VEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTLPSPG 304
           G+  T S K    +EK   K      K    PT P   ++   P L  P  P PT P   
Sbjct: 207 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT-PKAETTTKGPALTTPKEPTPTTPKEP 265

Query: 305 QILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTC 364
                K  P P T++  P           K       +P          TK+P   +   
Sbjct: 266 ASTTPKE-PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP------APTTTKEPAPTTPKE 318

Query: 365 KTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQE 424
              + T+  A     K       E    T +K     P    P  P ++P P  P+    
Sbjct: 319 PAPTTTKEPAPT-TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-KEPTPTTPKEPAP 376

Query: 425 PHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPAT 484
             + P    P E  P    KP P TP  P P   P +   +   +P P   +P  P P T
Sbjct: 377 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKEPSPT--TPKEPAPTT 433

Query: 485 EPASRLSSEE 494
             ++  +++E
Sbjct: 434 TKSAPTTTKE 443



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 105/516 (20%), Positives = 171/516 (33%), Gaps = 56/516 (10%)

Query: 213  SASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKS 272
            +A ++  KL  +  EKL      +P     +   P     T   +     P+        
Sbjct: 523  TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-----TTPEEPTPTTPEEPAPTTPK 577

Query: 273  AVGPTCPATVSSLV--KPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNNRK 330
            A  P  P   +     +P    P  P PT P        KG  AP TL K+P   +    
Sbjct: 578  AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT-APTTL-KEPAPTTP--- 632

Query: 331  FLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTC-KTHSLTQRRAVQGRRKRFDVLLAEH 389
               K+ + +E  P          TK+P   S TC K    T +       K       + 
Sbjct: 633  ---KKPAPKELAPTT--------TKEPT--STTCDKPAPTTPKGTAPTTPKEPAPTTPKE 679

Query: 390  KNKTREKELIRHPDSQQPPQPLRDPHPAP----PRTSQEP----HQNPHGVIPSESKPFV 441
               T  K     P + + P P     PAP    P T++ P       P    P E+ P  
Sbjct: 680  PAPTTPKGTA--PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 737

Query: 442  ASKPKPHTPSLPRP----PGCPAQQGGSAPI---DPPPVHESPHPPLPATEPASRLSSEE 494
              +P P TP  P P       P     S P    +P  +H+SP    P  E ++  + + 
Sbjct: 738  PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP--ELSAEPTPKA 795

Query: 495  GEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWN---RLRCALNLMV 551
             E   KE  V       +    +P    T   +   R             ++        
Sbjct: 796  LENSPKEPGVPTTKTPAA---TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTT 852

Query: 552  EKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCI 611
            EK   +++      V STT+  +T     T    T    V+       +T  +       
Sbjct: 853  EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETA 912

Query: 612  SPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSR---QVSSSSSSPSTPSGLSSVPS-SPM 667
             P  ++  +  TT   Q        P  + + +   +V    ++P+     S++P  +P 
Sbjct: 913  KPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 972

Query: 668  SRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGS 703
            SR  + +  + + RP ++  +     N  S  +GG+
Sbjct: 973  SRIAEAMLQT-TTRPNQTPNSKLVEVNPKSEDAGGA 1007



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 61/284 (21%), Positives = 92/284 (32%), Gaps = 48/284 (16%)

Query: 410 PLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGC--PA-QQGGSA 466
           P     PAP  T   P        P E  P    +P P TP  P P     PA     SA
Sbjct: 282 PTTPKEPAPTTTKSAP------TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 335

Query: 467 PIDP-PPVHESPHPPLPAT--EPASRLSSEEGEGDDKEES-VEKLDCHYSGHHPQPASFC 522
           P  P  P   +P  P P T  EPA     E      KE +   K     +   P P +  
Sbjct: 336 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA-- 393

Query: 523 TFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTN 582
                                        +K       +  P  P   +P +T+ P  T 
Sbjct: 394 ----------------------------PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT- 424

Query: 583 SVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQ 642
             P      +  +A T +  P   ++T  +P +   P+  TT   +PA +   +P  +  
Sbjct: 425 -TPKEPAPTTTKSAPTTTKEPA-PTTTKSAPTTPKEPSPTTT--KEPAPTTPKEPAPTTP 480

Query: 643 SRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESS 686
            +   ++   P+  +     P++     P   K      PKE++
Sbjct: 481 KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 524



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 108/526 (20%), Positives = 153/526 (29%), Gaps = 89/526 (16%)

Query: 268 TLLKSAVGPTCPATVSSLV--KPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDN 325
           T  KSA  PT P   +     KP    P  P PT P        K  PAP T E  P   
Sbjct: 330 TTTKSA--PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE-PAPTTKEPAPTTP 386

Query: 326 SNNRKFLNKR---LSEREFDPDIHCGVIDLDTKKPCTRS------LTCKTHSLTQRRAVQ 376
                   K+    + +E  P          TK+P   +       T K+   T +    
Sbjct: 387 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 446

Query: 377 GRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSE 436
              K       E    T ++     P    P  P + P P  P+        P    P E
Sbjct: 447 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP-KKPAPTTPK-------EPAPTTPKE 498

Query: 437 SKPFVASKPKPHTPSLPRP---------------PGCPAQQGGSAPIDPPPVHE------ 475
             P    KP P TP  P P               P  P +   + P  P P         
Sbjct: 499 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 558

Query: 476 SPHPPLPAT--EPASRLSSEEGEGDDKEES--VEKLDCHYSGHHPQPASFC-TFGSRQIG 530
           +P  P P T  EPA            KE +    K     +   P P +   T  +   G
Sbjct: 559 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 618

Query: 531 RGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNS---VPTS 587
                                 K       KK  P P   +P +T+ P  T      PT+
Sbjct: 619 TAPTTL----------------KEPAPTTPKK--PAPKELAPTTTKEPTSTTCDKPAPTT 660

Query: 588 QCGVSYLA----AATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQS 643
             G +       A T    P   +    +P +   PA  T     P     + P  +   
Sbjct: 661 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE---LAPTTTKGP 717

Query: 644 RQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGS 703
              +S   +P+TP    + P++P    P   K      P+     ++     +++     
Sbjct: 718 TSTTSDKPAPTTPK--ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT----- 770

Query: 704 GKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPST 749
                   P  +H S   S+   S+       +N     G P   T
Sbjct: 771 ------KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT 810



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 7/114 (6%)

Query: 581 TNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSV----PAHGTTLNAQPAASGAMD 636
           T +  TS  G     +A  + S    S+  ++P SK +    P   TT    PA +   +
Sbjct: 198 TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG-PALTTPKE 256

Query: 637 PVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNST 690
           P  +      S++   P TP+ + S P++P    P   KS+ +  PKE +  +T
Sbjct: 257 PTPTTPKEPASTTPKEP-TPTTIKSAPTTPKEPAPTTTKSAPT-TPKEPAPTTT 308



 Score = 32.0 bits (71), Expect = 2.8
 Identities = 27/151 (17%), Positives = 51/151 (33%), Gaps = 9/151 (5%)

Query: 564 PPVPSTTSPISTR--IPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAH 621
           P  P   +P +T+   P  T S PT+             T+P   + T     + + P  
Sbjct: 313 PTTPKEPAPTTTKEPAPTTTKSAPTTP-------KEPAPTTPKKPAPTTPKEPAPTTPKE 365

Query: 622 GTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLR 681
            T    +  A    +P  +       ++   P+  +     P++P    P   K      
Sbjct: 366 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 425

Query: 682 PKESSGNSTNCQNASSSTSGGSGKKRKNSSP 712
           PKE +  +T     ++     +  K   ++P
Sbjct: 426 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 456


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 67/300 (22%), Positives = 92/300 (30%), Gaps = 68/300 (22%)

Query: 402 PDSQQPPQPLRDPHPAP------PRTSQEP----HQNPHGVIPSESKPFVASKPKPHTPS 451
           P + + P P     PAP      P T +EP     + P    P E  P    +P P TP 
Sbjct: 365 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK 424

Query: 452 LPRP------PGCPAQQGGSAPIDPPPVHESPHPPLPAT--EPASRLSSEEGEGDDKEES 503
            P P      P  P +   +AP  P P   +P  P P T  EPA   + E      KE  
Sbjct: 425 EPAPTTKEPAPTTPKEPAPTAPKKPAPT--TPKEPAPTTPKEPAPTTTKEPSPTTPKE-- 480

Query: 504 VEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKI 563
                         PA   T  +                          K       K  
Sbjct: 481 --------------PAPTTTKSAP----------------------TTTKEPAPTTTKSA 504

Query: 564 PPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT 623
           P  P   SP +T+ P  T              A T    P   +    +P +   PA  T
Sbjct: 505 PTTPKEPSPTTTKEPAPTTPKE---------PAPTTPKKPAPTTPKEPAPTTPKEPAPTT 555

Query: 624 TLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS-SVPSSPMSRKPQKLKSSKSLRP 682
           T    P       P    ++   +    +P+TP  L+ + P  P    P++L  +    P
Sbjct: 556 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 615



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 59/250 (23%), Positives = 84/250 (33%), Gaps = 17/250 (6%)

Query: 249 GRIMTPSVK----VEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTLPSPG 304
           G+  T S K    +EK   K      K    PT P   ++   P L  P  P PT P   
Sbjct: 259 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT-PKAETTTKGPALTTPKEPTPTTPKEP 317

Query: 305 QILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTC 364
                K  P P T++  P           K       +P          TK+P   +   
Sbjct: 318 ASTTPKE-PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP------APTTTKEPAPTTPKE 370

Query: 365 KTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQE 424
              + T+  A     K       E    T +K     P    P  P ++P P  P+    
Sbjct: 371 PAPTTTKEPAPT-TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-KEPTPTTPKEPAP 428

Query: 425 PHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPAT 484
             + P    P E  P    KP P TP  P P   P +   +   +P P   +P  P P T
Sbjct: 429 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKEPSPT--TPKEPAPTT 485

Query: 485 EPASRLSSEE 494
             ++  +++E
Sbjct: 486 TKSAPTTTKE 495



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 119/569 (20%), Positives = 183/569 (32%), Gaps = 69/569 (12%)

Query: 139 CPAHDDFYLVVCNDCN-----QVVKPQAFQSHYERRHSSSSKPPLAVPPTSVFSFFPSLS 193
           CP ++ F   V N  +     +   P       +     S KPP       V     S  
Sbjct: 56  CPDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIE---SEE 112

Query: 194 KSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSRVPHGRIMT 253
            ++  S S +  SSS    S+SSS+ + +KS K     R   + +      +    +  T
Sbjct: 113 ITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPT 172

Query: 254 PSVKV-EKIHPKMDGTLLKSAVGPTCPAT---VSSLVKPGLNCPSIPKPTLPSPGQILNG 309
           P   V ++    +D    K     T       VS+  K     P  P+P+LP        
Sbjct: 173 PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKE 232

Query: 310 KGLPA--PPTLEKKPEDNSNNRKFLN---KRLSEREFDPDIHCGVIDLDTKKPCTRSLTC 364
             L      T+E K    +N +   +   K  S +E          DL          T 
Sbjct: 233 TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP 292

Query: 365 KTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQE 424
           K  + T+  A+   ++       E  + T  KE         P  P     PAP  T   
Sbjct: 293 KAETTTKGPALTTPKEPTPTTPKEPASTT-PKEPTPTTIKSAPTTP---KEPAPTTTKSA 348

Query: 425 PHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGC--PA-QQGGSAPIDP-PPVHESPHPP 480
           P        P E  P    +P P TP  P P     PA     SAP  P  P   +P  P
Sbjct: 349 P------TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 402

Query: 481 LPAT--EPASRLSSEEGEGDDKEES-VEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFD 537
            P T  EPA     E      KE +   K     +   P P +                 
Sbjct: 403 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA----------------- 445

Query: 538 SRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAA 597
                         +K       +  P  P   +P +T+ P  T   P      +  +A 
Sbjct: 446 -------------PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT--TPKEPAPTTTKSAP 490

Query: 598 TVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPS 657
           T +  P   ++T  +P +   P+  TT   +PA +   +P  +   +   ++   P+  +
Sbjct: 491 TTTKEPA-PTTTKSAPTTPKEPSPTTT--KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 547

Query: 658 GLSSVPSSPMSRKPQKLKSSKSLRPKESS 686
                P++     P   K      PKE++
Sbjct: 548 PKEPAPTTTKKPAPTTPKEPAPTTPKETA 576



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 105/516 (20%), Positives = 171/516 (33%), Gaps = 56/516 (10%)

Query: 213  SASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKS 272
            +A ++  KL  +  EKL      +P     +   P     T   +     P+        
Sbjct: 575  TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-----TTPEEPTPTTPEEPAPTTPK 629

Query: 273  AVGPTCPATVSSLV--KPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNNRK 330
            A  P  P   +     +P    P  P PT P        KG  AP TL K+P   +    
Sbjct: 630  AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT-APTTL-KEPAPTTP--- 684

Query: 331  FLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTC-KTHSLTQRRAVQGRRKRFDVLLAEH 389
               K+ + +E  P          TK+P   S TC K    T +       K       + 
Sbjct: 685  ---KKPAPKELAPTT--------TKEPT--STTCDKPAPTTPKGTAPTTPKEPAPTTPKE 731

Query: 390  KNKTREKELIRHPDSQQPPQPLRDPHPAP----PRTSQEP----HQNPHGVIPSESKPFV 441
               T  K     P + + P P     PAP    P T++ P       P    P E+ P  
Sbjct: 732  PAPTTPKGTA--PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 789

Query: 442  ASKPKPHTPSLPRP----PGCPAQQGGSAPI---DPPPVHESPHPPLPATEPASRLSSEE 494
              +P P TP  P P       P     S P    +P  +H+SP    P  E ++  + + 
Sbjct: 790  PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP--ELSAEPTPKA 847

Query: 495  GEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWN---RLRCALNLMV 551
             E   KE  V       +    +P    T   +   R             ++        
Sbjct: 848  LENSPKEPGVPTTKTPAA---TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTT 904

Query: 552  EKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCI 611
            EK   +++      V STT+  +T     T    T    V+       +T  +       
Sbjct: 905  EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETA 964

Query: 612  SPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSR---QVSSSSSSPSTPSGLSSVPS-SPM 667
             P  ++  +  TT   Q        P  + + +   +V    ++P+     S++P  +P 
Sbjct: 965  KPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 1024

Query: 668  SRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGS 703
            SR  + +  + + RP ++  +     N  S  +GG+
Sbjct: 1025 SRIAEAMLQT-TTRPNQTPNSKLVEVNPKSEDAGGA 1059



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 108/526 (20%), Positives = 153/526 (29%), Gaps = 89/526 (16%)

Query: 268 TLLKSAVGPTCPATVSSLV--KPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDN 325
           T  KSA  PT P   +     KP    P  P PT P        K  PAP T E  P   
Sbjct: 382 TTTKSA--PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE-PAPTTKEPAPTTP 438

Query: 326 SNNRKFLNKR---LSEREFDPDIHCGVIDLDTKKPCTRS------LTCKTHSLTQRRAVQ 376
                   K+    + +E  P          TK+P   +       T K+   T +    
Sbjct: 439 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 498

Query: 377 GRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSE 436
              K       E    T ++     P    P  P + P P  P+        P    P E
Sbjct: 499 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP-KKPAPTTPK-------EPAPTTPKE 550

Query: 437 SKPFVASKPKPHTPSLPRP---------------PGCPAQQGGSAPIDPPPVHE------ 475
             P    KP P TP  P P               P  P +   + P  P P         
Sbjct: 551 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 610

Query: 476 SPHPPLPAT--EPASRLSSEEGEGDDKEES--VEKLDCHYSGHHPQPASFC-TFGSRQIG 530
           +P  P P T  EPA            KE +    K     +   P P +   T  +   G
Sbjct: 611 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 670

Query: 531 RGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNS---VPTS 587
                                 K       KK  P P   +P +T+ P  T      PT+
Sbjct: 671 TAPTTL----------------KEPAPTTPKK--PAPKELAPTTTKEPTSTTCDKPAPTT 712

Query: 588 QCGVSYLA----AATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQS 643
             G +       A T    P   +    +P +   PA  T     P     + P  +   
Sbjct: 713 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE---LAPTTTKGP 769

Query: 644 RQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGS 703
              +S   +P+TP    + P++P    P   K      P+     ++     +++     
Sbjct: 770 TSTTSDKPAPTTPK--ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT----- 822

Query: 704 GKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPST 749
                   P  +H S   S+   S+       +N     G P   T
Sbjct: 823 ------KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT 862



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 25/110 (22%), Positives = 42/110 (38%), Gaps = 3/110 (2%)

Query: 649 SSSSPSTPSGLSSVPSSPMSRKPQ---KLKSSKSLRPKESSGNSTNCQNASSSTSGGSGK 705
           SS     PSG S    S   R P+   K K+ K +  +E +   +  +N  SS+S  S  
Sbjct: 74  SSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSS 133

Query: 706 KRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHS 755
                  +    +S+++        ++  +KN       P P  V  + S
Sbjct: 134 SSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGS 183



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 7/114 (6%)

Query: 581 TNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSV----PAHGTTLNAQPAASGAMD 636
           T +  TS  G     +A  + S    S+  ++P SK +    P   TT    PA +   +
Sbjct: 250 TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG-PALTTPKE 308

Query: 637 PVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNST 690
           P  +      S++   P TP+ + S P++P    P   KS+ +  PKE +  +T
Sbjct: 309 PTPTTPKEPASTTPKEP-TPTTIKSAPTTPKEPAPTTTKSAPT-TPKEPAPTTT 360



 Score = 32.0 bits (71), Expect = 2.8
 Identities = 27/151 (17%), Positives = 51/151 (33%), Gaps = 9/151 (5%)

Query: 564 PPVPSTTSPISTR--IPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAH 621
           P  P   +P +T+   P  T S PT+             T+P   + T     + + P  
Sbjct: 365 PTTPKEPAPTTTKEPAPTTTKSAPTTP-------KEPAPTTPKKPAPTTPKEPAPTTPKE 417

Query: 622 GTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLR 681
            T    +  A    +P  +       ++   P+  +     P++P    P   K      
Sbjct: 418 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 477

Query: 682 PKESSGNSTNCQNASSSTSGGSGKKRKNSSP 712
           PKE +  +T     ++     +  K   ++P
Sbjct: 478 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 508


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 67/300 (22%), Positives = 92/300 (30%), Gaps = 68/300 (22%)

Query: 402 PDSQQPPQPLRDPHPAP------PRTSQEP----HQNPHGVIPSESKPFVASKPKPHTPS 451
           P + + P P     PAP      P T +EP     + P    P E  P    +P P TP 
Sbjct: 406 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK 465

Query: 452 LPRP------PGCPAQQGGSAPIDPPPVHESPHPPLPAT--EPASRLSSEEGEGDDKEES 503
            P P      P  P +   +AP  P P   +P  P P T  EPA   + E      KE  
Sbjct: 466 EPAPTTKEPAPTTPKEPAPTAPKKPAPT--TPKEPAPTTPKEPAPTTTKEPSPTTPKE-- 521

Query: 504 VEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKI 563
                         PA   T  +                          K       K  
Sbjct: 522 --------------PAPTTTKSAP----------------------TTTKEPAPTTTKSA 545

Query: 564 PPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT 623
           P  P   SP +T+ P  T              A T    P   +    +P +   PA  T
Sbjct: 546 PTTPKEPSPTTTKEPAPTTPKE---------PAPTTPKKPAPTTPKEPAPTTPKEPAPTT 596

Query: 624 TLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS-SVPSSPMSRKPQKLKSSKSLRP 682
           T    P       P    ++   +    +P+TP  L+ + P  P    P++L  +    P
Sbjct: 597 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 656



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 59/250 (23%), Positives = 84/250 (33%), Gaps = 17/250 (6%)

Query: 249 GRIMTPSVK----VEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTLPSPG 304
           G+  T S K    +EK   K      K    PT P   ++   P L  P  P PT P   
Sbjct: 300 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT-PKAETTTKGPALTTPKEPTPTTPKEP 358

Query: 305 QILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTC 364
                K  P P T++  P           K       +P          TK+P   +   
Sbjct: 359 ASTTPKE-PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP------APTTTKEPAPTTPKE 411

Query: 365 KTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQE 424
              + T+  A     K       E    T +K     P    P  P ++P P  P+    
Sbjct: 412 PAPTTTKEPAPT-TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-KEPTPTTPKEPAP 469

Query: 425 PHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPAT 484
             + P    P E  P    KP P TP  P P   P +   +   +P P   +P  P P T
Sbjct: 470 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKEPSPT--TPKEPAPTT 526

Query: 485 EPASRLSSEE 494
             ++  +++E
Sbjct: 527 TKSAPTTTKE 536



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 119/569 (20%), Positives = 183/569 (32%), Gaps = 69/569 (12%)

Query: 139 CPAHDDFYLVVCNDCN-----QVVKPQAFQSHYERRHSSSSKPPLAVPPTSVFSFFPSLS 193
           CP ++ F   V N  +     +   P       +     S KPP       V     S  
Sbjct: 97  CPDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIE---SEE 153

Query: 194 KSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSRVPHGRIMT 253
            ++  S S +  SSS    S+SSS+ + +KS K     R   + +      +    +  T
Sbjct: 154 ITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPT 213

Query: 254 PSVKV-EKIHPKMDGTLLKSAVGPTCPAT---VSSLVKPGLNCPSIPKPTLPSPGQILNG 309
           P   V ++    +D    K     T       VS+  K     P  P+P+LP        
Sbjct: 214 PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKE 273

Query: 310 KGLPA--PPTLEKKPEDNSNNRKFLN---KRLSEREFDPDIHCGVIDLDTKKPCTRSLTC 364
             L      T+E K    +N +   +   K  S +E          DL          T 
Sbjct: 274 TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP 333

Query: 365 KTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQE 424
           K  + T+  A+   ++       E  + T  KE         P  P     PAP  T   
Sbjct: 334 KAETTTKGPALTTPKEPTPTTPKEPASTT-PKEPTPTTIKSAPTTP---KEPAPTTTKSA 389

Query: 425 PHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGC--PA-QQGGSAPIDP-PPVHESPHPP 480
           P        P E  P    +P P TP  P P     PA     SAP  P  P   +P  P
Sbjct: 390 P------TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 443

Query: 481 LPAT--EPASRLSSEEGEGDDKEES-VEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFD 537
            P T  EPA     E      KE +   K     +   P P +                 
Sbjct: 444 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA----------------- 486

Query: 538 SRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAA 597
                         +K       +  P  P   +P +T+ P  T   P      +  +A 
Sbjct: 487 -------------PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT--TPKEPAPTTTKSAP 531

Query: 598 TVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPS 657
           T +  P   ++T  +P +   P+  TT   +PA +   +P  +   +   ++   P+  +
Sbjct: 532 TTTKEPA-PTTTKSAPTTPKEPSPTTT--KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 588

Query: 658 GLSSVPSSPMSRKPQKLKSSKSLRPKESS 686
                P++     P   K      PKE++
Sbjct: 589 PKEPAPTTTKKPAPTTPKEPAPTTPKETA 617



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 105/516 (20%), Positives = 171/516 (33%), Gaps = 56/516 (10%)

Query: 213  SASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKS 272
            +A ++  KL  +  EKL      +P     +   P     T   +     P+        
Sbjct: 616  TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-----TTPEEPTPTTPEEPAPTTPK 670

Query: 273  AVGPTCPATVSSLV--KPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNNRK 330
            A  P  P   +     +P    P  P PT P        KG  AP TL K+P   +    
Sbjct: 671  AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT-APTTL-KEPAPTTP--- 725

Query: 331  FLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTC-KTHSLTQRRAVQGRRKRFDVLLAEH 389
               K+ + +E  P          TK+P   S TC K    T +       K       + 
Sbjct: 726  ---KKPAPKELAPTT--------TKEPT--STTCDKPAPTTPKGTAPTTPKEPAPTTPKE 772

Query: 390  KNKTREKELIRHPDSQQPPQPLRDPHPAP----PRTSQEP----HQNPHGVIPSESKPFV 441
               T  K     P + + P P     PAP    P T++ P       P    P E+ P  
Sbjct: 773  PAPTTPKGTA--PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 830

Query: 442  ASKPKPHTPSLPRP----PGCPAQQGGSAPI---DPPPVHESPHPPLPATEPASRLSSEE 494
              +P P TP  P P       P     S P    +P  +H+SP    P  E ++  + + 
Sbjct: 831  PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP--ELSAEPTPKA 888

Query: 495  GEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWN---RLRCALNLMV 551
             E   KE  V       +    +P    T   +   R             ++        
Sbjct: 889  LENSPKEPGVPTTKTPAA---TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTT 945

Query: 552  EKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCI 611
            EK   +++      V STT+  +T     T    T    V+       +T  +       
Sbjct: 946  EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETA 1005

Query: 612  SPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSR---QVSSSSSSPSTPSGLSSVPS-SPM 667
             P  ++  +  TT   Q        P  + + +   +V    ++P+     S++P  +P 
Sbjct: 1006 KPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 1065

Query: 668  SRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGS 703
            SR  + +  + + RP ++  +     N  S  +GG+
Sbjct: 1066 SRIAEAMLQT-TTRPNQTPNSKLVEVNPKSEDAGGA 1100



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 108/526 (20%), Positives = 153/526 (29%), Gaps = 89/526 (16%)

Query: 268 TLLKSAVGPTCPATVSSLV--KPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDN 325
           T  KSA  PT P   +     KP    P  P PT P        K  PAP T E  P   
Sbjct: 423 TTTKSA--PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE-PAPTTKEPAPTTP 479

Query: 326 SNNRKFLNKR---LSEREFDPDIHCGVIDLDTKKPCTRS------LTCKTHSLTQRRAVQ 376
                   K+    + +E  P          TK+P   +       T K+   T +    
Sbjct: 480 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 539

Query: 377 GRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSE 436
              K       E    T ++     P    P  P + P P  P+        P    P E
Sbjct: 540 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP-KKPAPTTPK-------EPAPTTPKE 591

Query: 437 SKPFVASKPKPHTPSLPRP---------------PGCPAQQGGSAPIDPPPVHE------ 475
             P    KP P TP  P P               P  P +   + P  P P         
Sbjct: 592 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 651

Query: 476 SPHPPLPAT--EPASRLSSEEGEGDDKEES--VEKLDCHYSGHHPQPASFC-TFGSRQIG 530
           +P  P P T  EPA            KE +    K     +   P P +   T  +   G
Sbjct: 652 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 711

Query: 531 RGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNS---VPTS 587
                                 K       KK  P P   +P +T+ P  T      PT+
Sbjct: 712 TAPTTL----------------KEPAPTTPKK--PAPKELAPTTTKEPTSTTCDKPAPTT 753

Query: 588 QCGVSYLA----AATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQS 643
             G +       A T    P   +    +P +   PA  T     P     + P  +   
Sbjct: 754 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE---LAPTTTKGP 810

Query: 644 RQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGS 703
              +S   +P+TP    + P++P    P   K      P+     ++     +++     
Sbjct: 811 TSTTSDKPAPTTPK--ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT----- 863

Query: 704 GKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPST 749
                   P  +H S   S+   S+       +N     G P   T
Sbjct: 864 ------KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT 903



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 25/110 (22%), Positives = 42/110 (38%), Gaps = 3/110 (2%)

Query: 649 SSSSPSTPSGLSSVPSSPMSRKPQ---KLKSSKSLRPKESSGNSTNCQNASSSTSGGSGK 705
           SS     PSG S    S   R P+   K K+ K +  +E +   +  +N  SS+S  S  
Sbjct: 115 SSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSS 174

Query: 706 KRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHS 755
                  +    +S+++        ++  +KN       P P  V  + S
Sbjct: 175 SSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGS 224



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 7/114 (6%)

Query: 581 TNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSV----PAHGTTLNAQPAASGAMD 636
           T +  TS  G     +A  + S    S+  ++P SK +    P   TT    PA +   +
Sbjct: 291 TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG-PALTTPKE 349

Query: 637 PVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNST 690
           P  +      S++   P TP+ + S P++P    P   KS+ +  PKE +  +T
Sbjct: 350 PTPTTPKEPASTTPKEP-TPTTIKSAPTTPKEPAPTTTKSAPT-TPKEPAPTTT 401



 Score = 32.0 bits (71), Expect = 2.8
 Identities = 27/151 (17%), Positives = 51/151 (33%), Gaps = 9/151 (5%)

Query: 564 PPVPSTTSPISTR--IPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAH 621
           P  P   +P +T+   P  T S PT+             T+P   + T     + + P  
Sbjct: 406 PTTPKEPAPTTTKEPAPTTTKSAPTTP-------KEPAPTTPKKPAPTTPKEPAPTTPKE 458

Query: 622 GTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLR 681
            T    +  A    +P  +       ++   P+  +     P++P    P   K      
Sbjct: 459 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 518

Query: 682 PKESSGNSTNCQNASSSTSGGSGKKRKNSSP 712
           PKE +  +T     ++     +  K   ++P
Sbjct: 519 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 549


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 121/549 (22%), Positives = 175/549 (31%), Gaps = 95/549 (17%)

Query: 32   QQQQQQQQPPPPQPQRQQHPPPPPRRTRPEDGG---PGAASTSAAAMATVGE-----RR- 82
            Q    Q  PPPP P     PPPPP       GG   P   ST    +          RR 
Sbjct: 1031 QSGPHQAAPPPPPP-----PPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRD 1085

Query: 83   -PLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNREVMGLCREDMPI-----F 136
             P  +P+ +  Q +    +  K        L+       +  +++  CR    +      
Sbjct: 1086 PPFQTPKKLYAQEYEFEADEDKADVPADIRLNPR-----RLPDLVSSCRSRPALSPLGDI 1140

Query: 137  GFCPAHDDFYLVVCNDCNQVVKP-QAFQSHYERRHSSSSKPPLAVP----PTSVFSFFPS 191
             FCP +            +  KP +A +    R        PL VP    P S  +    
Sbjct: 1141 DFCPPNPG----PDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDG 1196

Query: 192  LSKSKG-GSASGSNRSSSGGVLSASSSSSKL-LKSPKEKLQLRGNTRPM-----HPIQQS 244
              K +G G   G     +GG         K+ L  PK    L  ++        H    S
Sbjct: 1197 AKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDS 1256

Query: 245  RVPHGRIMTPSVKVEKIHPKMDGTLLKSAV-----GPTCPATVSSLVKPGLNCPSIPKPT 299
             +   +I     +VE+  P+M    + S +     G   P    + + P L+ P    P+
Sbjct: 1257 SLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPS 1316

Query: 300  LPSPG----------------------------QILNGKGLPAPPTLEKKPEDNSNNRKF 331
            +P+ G                                G GL  P   ++  E+   N + 
Sbjct: 1317 VPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLET 1376

Query: 332  LNKRLSE--------REFDPDIHCGVIDLDTKKPCTRSLTCKTHS--LTQRRAVQGRRKR 381
            L    S+        R+    I   +  LD         T       L    AV G    
Sbjct: 1377 LPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPP- 1435

Query: 382  FDVLLAEHKNKTREKELIRH-PDSQQPPQPLRDPHPAPPRTSQEPH--QNPHGVIPSESK 438
               L + + N T E  L+   P    PP P   P P PP    +P     P  V P+ S 
Sbjct: 1436 LPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSS 1495

Query: 439  PFVASKPKPHTPSLPRPPGCPAQQGG--SAPIDPPPVHESPHPPLPATEPASRLSSEE-- 494
            P     P P  P++P PP  P       +AP + P       P LP T P      +E  
Sbjct: 1496 PPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETA 1555

Query: 495  ---GEGDDK 500
               GE D++
Sbjct: 1556 AVCGETDEE 1564



 Score = 38.5 bits (88), Expect = 0.030
 Identities = 31/104 (29%), Positives = 39/104 (37%), Gaps = 23/104 (22%)

Query: 402  PDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQ 461
            P+ +  P+    P P PP        +P+G       P  AS   P TP L   P  P +
Sbjct: 968  PEDEGDPKAGAGPPPGPPA------YDPYGPYC----PGRASGAGPETPGLGLDPNKPPE 1017

Query: 462  -------------QGGSAPIDPPPVHESPHPPLPATEPASRLSS 492
                         Q G     PPP    P PP PA+EP   L+S
Sbjct: 1018 LPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTS 1061



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 28/91 (30%), Positives = 35/91 (38%), Gaps = 22/91 (24%)

Query: 411 LRDPHPAPPRTSQEPHQNPHGVI---PSESKPFVASKPKP--------HTPSLPRPPGC- 458
           L+   P PP T+Q     PHG++        P V   P P        H PS P P    
Sbjct: 760 LQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPS-PSPSASK 818

Query: 459 -------PAQQGGSAPIDPPPVHESPHPPLP 482
                  PA + G+    PPP    P PP+P
Sbjct: 819 VGVHLLEPATRDGAP--QPPPPPPPPPPPMP 847



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 9/94 (9%)

Query: 406 QPPQPLRDPHPAPPRTSQ-EPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGG 464
           QPP P   P P PP   Q E H   HG+ P+   P +  +      SL  P       G 
Sbjct: 834 QPPPP--PPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPE-----ESLDPPGAMQELLGA 886

Query: 465 SAPIDPPPVHESPHPP-LPATEPASRLSSEEGEG 497
             P+ P P      PP     +PA    S   +G
Sbjct: 887 LEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQG 920



 Score = 32.0 bits (71), Expect = 2.8
 Identities = 31/121 (25%), Positives = 43/121 (35%), Gaps = 16/121 (13%)

Query: 376  QGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPS 435
            + R +R  V   E+ NK     +       +PP P+R       R+ Q   +NP     S
Sbjct: 1639 KNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVR-------RSGQA--KNPVSAGGS 1689

Query: 436  ESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRLSSEEG 495
                   S P P  P+ P  P  P +     P +  P    P PP P      R   +E 
Sbjct: 1690 -------SAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEK 1742

Query: 496  E 496
            E
Sbjct: 1743 E 1743


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 105/514 (20%), Positives = 174/514 (33%), Gaps = 85/514 (16%)

Query: 405  QQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGG 464
            + PP        A  + S+   ++P   +P            P  P  P PP  P     
Sbjct: 1010 KMPPAEKASRIRAAEKVSRGDQESPDACLP------------PTVPEAPAPPQKPLNSQS 1057

Query: 465  SAPIDPPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTF 524
               + PPP+     P LP+ +P  R + ++G    +E     L       HP+P      
Sbjct: 1058 QKHLAPPPLLS---PLLPSIKPTVRKTRQDG---SQEAPEAPLSSELEPFHPKPKIRTRK 1111

Query: 525  GSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSV 584
             SR                  A +   E H +    + + P P++    +TR     +SV
Sbjct: 1112 SSRMTPFP-------------ATSAAPEPHPSTSTAQPVTPKPTSQ---ATRSRTNRSSV 1155

Query: 585  PTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDP---VCSM 641
             T +          V T+P L  ST       S P    T   + + S    P   V + 
Sbjct: 1156 KTPE--------PVVPTAPELQPSTSTDQPVTSEPTSQVT-RGRKSRSSVKTPETVVPTA 1206

Query: 642  QSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQK-----LKSSKSLRPKESSGNSTNCQNAS 696
               Q S+S+  P T    S       +R   K     + ++  L+P  S+      +   
Sbjct: 1207 LELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTY 1266

Query: 697  SSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSI 756
             +T G   +    +   +V ++     S+S+   +             P P++ T+    
Sbjct: 1267 QATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPV------------TPKPTSRTTRSRT 1314

Query: 757  GLNCVTNKANAV--------NVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFI 808
             ++ V      V        +   DQ     PT     S   MS  V + +ST+ + P +
Sbjct: 1315 NMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMS-SVKNPESTVPIAPEL 1373

Query: 809  --HQSNELPV---------NSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVA 857
                S E PV             + S   TP + L+    K  PS+S+    + +PT  A
Sbjct: 1374 PPSTSTEQPVTPEPTSRATRGRKNRSSGKTP-ETLVPTAPKLEPSTSTDQPVTPEPTSQA 1432

Query: 858  KVPAVNNVHMKHTGT-IPGAQGLMNSSLLHQDIS 890
                 N   +K   T +P A  L  S+   Q ++
Sbjct: 1433 TRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVT 1466


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 95/399 (23%), Positives = 152/399 (38%), Gaps = 68/399 (17%)

Query: 563  IPPVPSTTSP---ISTRIPHRTNSVPTSQCGVSYLA------AATVSTSPVLLSSTCISP 613
            +P  P+TTS    +ST      +S PT+    S         + TV +SPV  ++T    
Sbjct: 1842 MPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPA 1901

Query: 614  NSKS--VPAHGTTLNAQPA------------ASGAMDPVCSMQSRQVSSSSSSPSTPSGL 659
             S +  +    T  ++ P             ASG  +   +  S    + SS PST S L
Sbjct: 1902 RSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSAL 1961

Query: 660  SSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSG----KKRKNSSPLLV 715
               P+S  S  P    ++       +SG S     AS S+   +G      R  +S LL 
Sbjct: 1962 VEEPTSYHS-SPGSTATTHFPDSSTTSGRSEE-STASHSSQDATGTIVLPARSTTSVLLG 2019

Query: 716  HSSSSSSSSSS--------SSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANA 767
             S++S  SS S        S+ +     K+   HS P  P+T  S  S   + V+ ++  
Sbjct: 2020 ESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTT 2079

Query: 768  VNVRHDQSGRGP-PTGSPAESIKRMSVMVNSSD----------STLSLGPFIHQSNELPV 816
             + R   +     P  +    + R S   +SS           ST + GP     ++   
Sbjct: 2080 SHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGP-----SQEST 2134

Query: 817  NSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGA 876
             SH S   + T L          SP S++  +   + T     P   +  +    T   +
Sbjct: 2135 TSHSSPGSTDTAL----------SPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTT--S 2182

Query: 877  QGLMNSSL-LHQDISSPCLRTGISATSPQSPDLKSKGTS 914
             G++ +S  +H    SP  RT +S  S  SP L+ + T+
Sbjct: 2183 SGIVEASTRVHSSTGSP--RTTLSPASSTSPGLQGESTA 2219



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 96/410 (23%), Positives = 149/410 (36%), Gaps = 81/410 (19%)

Query: 552  EKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCI 611
            E+    Q W    P  S T+P     P  T +VP       +   ++  T+    SST +
Sbjct: 4218 EESTTFQSW----PSSSDTTPS----PPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTL 4269

Query: 612  SPNSKSVPAHGTTLNAQPAASG-AMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRK 670
              + +S     TT+++ P A+G A+ P  S  S  V   ++SP + SG +   + P S  
Sbjct: 4270 GRSEES-----TTVHSSPGATGTALFPTRSATSVLVGEPTTSPIS-SGSTETTALPGSTT 4323

Query: 671  PQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKK-RKNSSPLLVHSSSSSSSSSSSSH 729
               L    +          T    AS+++SG S +    +S P  +H+++  SS++    
Sbjct: 4324 TAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGV 4383

Query: 730  SMESFRKNCVAHSGPPYPSTV-----TSSHSIGLNCVTNKAN------------------ 766
            S ES      +HS P    T      T++ S+G    T  ++                  
Sbjct: 4384 SQES----TASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGL 4439

Query: 767  --AVNVRHDQSGRGPPTGSPAESIKRMSVMV------NSSDSTLSLGPFIHQSNELPVNS 818
              A    H  +G    T SPA S  R           NS D+T +         EL   S
Sbjct: 4440 LEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTS 4499

Query: 819  HGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMK--HTGTIPGA 876
            HG                   SPSS+   + S+  T + +      VH     T T P  
Sbjct: 4500 HG-------------------SPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSP 4540

Query: 877  QGLMNSSLLHQDI---SSPCLRTGISATS--PQSPDLKSKGTSLTAENST 921
                 S L+ +     SSP    G + T   P+S     +G   T  +S+
Sbjct: 4541 ARSTTSGLVEESTTYHSSP----GSTQTMHFPESNTTSGRGEESTTSHSS 4586



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 91/378 (24%), Positives = 142/378 (37%), Gaps = 56/378 (14%)

Query: 564  PPVPSTTSPI---STRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPA 620
            P  P+TTS     ST      +S+PT+        +  V  S    SS   S  +   P 
Sbjct: 788  PAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPG-STQTMHFPE 846

Query: 621  HGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSL 680
              TT       SG  +   +  S    + SS+PST S L   P+S  S  P    ++   
Sbjct: 847  SDTT-------SGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHS-SPGSTATTHFP 898

Query: 681  RPKESSGNSTNCQNASSSTSGGSG----KKRKNSSPLLVHSSSSSSSSSS--------SS 728
                +SG S     AS S+   +G      R  +S LL  S++S  SS S        S+
Sbjct: 899  DSSTTSGRSEE-STASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGST 957

Query: 729  HSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGP-PTGSPAES 787
             +     ++   HS P  P+T  S  S   + V+ ++     R   +     P  +    
Sbjct: 958  TTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPG 1017

Query: 788  IKRMSVMVNSSD----------STLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKR 837
            + R S   +SS           ST + GP     ++    SH S   + T L        
Sbjct: 1018 LSRHSTTSHSSPGSTDTTLLPASTTTSGP-----SQESTTSHSSSGSTDTAL-------- 1064

Query: 838  KCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSL-LHQDISSPCLRT 896
              SP S++  +   + T     P   +  +    T   + G++ +S  +H    SP  RT
Sbjct: 1065 --SPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTT--SSGIVEASTRVHSSTGSP--RT 1118

Query: 897  GISATSPQSPDLKSKGTS 914
             +S  S  SP L+ + T+
Sbjct: 1119 TLSPASSTSPGLQGESTA 1136



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 90/395 (22%), Positives = 150/395 (37%), Gaps = 36/395 (9%)

Query: 568  STTSPISTRIPHRTNS-VPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPA---HGT 623
            STT   S R P  T S   T+  GVS    +T S S    + T   P+S + P    H T
Sbjct: 3606 STTFHSSPRSPATTLSPASTTSSGVS--EESTTSHSRPGSTHTTAFPDSTTTPGLSRHST 3663

Query: 624  TLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKL-KSSKSLRP 682
            T ++ P ++       S  +   S  S++  + SG +    SP S       + S +   
Sbjct: 3664 TSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHS 3723

Query: 683  KESSGNSTNCQNASSSTSGGSGKKRKNS---SPLLVHSSSSSSSSSSSSHSMESFRKNCV 739
               S ++T   ++++S+       R +S   SP    S +SS+S      S         
Sbjct: 3724 SPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAS 3783

Query: 740  AHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESI-----KRMSVM 794
             H+ P  PST T+                   H   G  P T  PA S      ++ ++ 
Sbjct: 3784 THTTPSPPSTATA-----------PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF 3832

Query: 795  VNSSDSTLSLGPFIHQSNELPVNSHGS-FSHSHTPLDKLIGKKRK--CSPSSSSINNSSS 851
             +S D++ +     H +      S  S  S   T +  L G       S +S++  +S  
Sbjct: 3833 HSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPR 3892

Query: 852  KPTKVAKVPAVNNVHMKHTGTIPGAQ-GLMNSSLLHQDISSPCL---RTGISATSPQSPD 907
             PT      ++ ++ +    T   +Q G  +S++     ++P L    T + ++SP S +
Sbjct: 3893 SPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTE 3952

Query: 908  LKSKGTSLTAENSTGRNNADTFEDK-LHLHSALWT 941
                  S T   S  R    TF  +    H+ L+T
Sbjct: 3953 TTVFPRSTT--TSVRREEPTTFHSRPASTHTTLFT 3985



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 84/378 (22%), Positives = 146/378 (38%), Gaps = 37/378 (9%)

Query: 568  STTSPISTRIPHRTNS-VPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPA---HGT 623
            STT   S R P  T S   T+  GVS    +T S S    + T   P+S + P    H T
Sbjct: 2049 STTFHSSPRSPATTLSPASTTSSGVS--EESTTSHSRPGSTHTTAFPDSTTTPGLSRHST 2106

Query: 624  TLNAQPAASGA-MDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRP 682
            T ++ P ++   + P  +  S     S++S S+P    +  S   +      + S +   
Sbjct: 2107 TSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHS 2166

Query: 683  KESSGNSTNCQNASSSTSGGSGKKRKNSS---PLLVHSSSSSSSSSSSSHSMESFRKNCV 739
               S ++T   ++++S+       R +SS   P    S +SS+S      S         
Sbjct: 2167 SPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAS 2226

Query: 740  AHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESI-----KRMSVM 794
             H+ P  PST T+                   H   G  P T  PA S      ++ ++ 
Sbjct: 2227 THTTPSPPSTATA-----------PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF 2275

Query: 795  VNSSDSTLSLGPFIHQSNELPVNSHGS-FSHSHTPLDKLIGKKRK--CSPSSSSINNSSS 851
             +S D++ +     H +      S  S  S   T +  L G       S +S++  +S  
Sbjct: 2276 HSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPR 2335

Query: 852  KPTKVAKVPAVNNVHMKHTGTIPGAQ-GLMNSSLLHQDISSPCL---RTGISATSPQSPD 907
             PT      ++ ++ +    T   +Q G  +S++     ++P L    T + ++SP S +
Sbjct: 2336 SPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTE 2395

Query: 908  L----KSKGTSLTAENST 921
                 ++  TS+  E  T
Sbjct: 2396 TTVFPRTPTTSVRGEEPT 2413



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 93/392 (23%), Positives = 152/392 (38%), Gaps = 54/392 (13%)

Query: 568  STTSPISTRIPHRTNS-VPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLN 626
            STT   S R P  T S   T+  GVS    +T S S    + T   P S ++P       
Sbjct: 3248 STTFYSSPRSPDTTLSPASTTSSGVS--EESTTSHSRPGSTHTTAFPGSTTMPGVSQEST 3305

Query: 627  AQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLR---PK 683
            A  ++ G+ D   S  S   ++SS  P + +  S   S+  +  P    +S  L    P 
Sbjct: 3306 ASHSSPGSTDTTLSPGS--TTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPV 3363

Query: 684  ESSGNS--TNCQNASSSTSGG------SGKKRKNSSP-------------LLVHSSSSSS 722
             SS  S  T    A S+T  G      S    K+++P                H S SS+
Sbjct: 3364 HSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSST 3423

Query: 723  SS---SSSSHSMESFRKNCVAHSGP------PYPSTVTSSHSIGLNCVTNKA-NAVNVRH 772
             +   S+SS ++    ++   HS P      P P+  T+S  +  +   + +  +    H
Sbjct: 3424 PTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMH 3483

Query: 773  -----DQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHT 827
                   SGRG  + +   S         S+ S L   P  + S      S GS + +H 
Sbjct: 3484 FPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHS------SPGSTATTHF 3537

Query: 828  PLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQ 887
            P       + + S +S S  +++   T V    +  +V +  + T P + G M ++ L  
Sbjct: 3538 PDSSTTSGRSEESTASHSSQDATG--TIVLPARSTTSVLLGESTTSPISSGSMETTALPG 3595

Query: 888  DISSPCL--RTGISATSPQSPDLKSKGTSLTA 917
              ++P L  ++    +SP+SP       S T+
Sbjct: 3596 STTTPGLSEKSTTFHSSPRSPATTLSPASTTS 3627



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 82/386 (21%), Positives = 153/386 (39%), Gaps = 42/386 (10%)

Query: 568  STTSPISTRIPHRTNS-VPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLN 626
            STT   S R P  T S   T+  GVS    +T S S    + T   P S ++P       
Sbjct: 1691 STTFYSSPRSPDTTLSPASTTSSGVS--EESTTSHSRPGSTHTTAFPGSTTMPGVSQEST 1748

Query: 627  AQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESS 686
            A  ++ G+ D   S  S   ++SS  P + +  SS  S+  +  P    +S  L      
Sbjct: 1749 ASHSSPGSTDTTLSPGS--TTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPV 1806

Query: 687  GNSTNCQNASSSTSGGSGKKRKNSS------------------------PLLVHSSSSSS 722
             +ST   + + S +G + ++ ++++                            H S SS+
Sbjct: 1807 HSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSST 1866

Query: 723  SS---SSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVR--HDQSGR 777
             +   S+SS ++    ++   HS P   +T  S      + +  ++ A +      Q+  
Sbjct: 1867 PTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMH 1926

Query: 778  GPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQS-NELPVNSH---GSFSHSHTPLDKLI 833
             P + + +   +      +S+  T+S  P    +  E P + H   GS + +H P     
Sbjct: 1927 FPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTT 1986

Query: 834  GKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQDISSPC 893
              + + S +S S  +++   T V    +  +V +  + T P + G M ++ L    ++P 
Sbjct: 1987 SGRSEESTASHSSQDATG--TIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPG 2044

Query: 894  L--RTGISATSPQSPDLKSKGTSLTA 917
            L  ++    +SP+SP       S T+
Sbjct: 2045 LSEKSTTFHSSPRSPATTLSPASTTS 2070



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 90/414 (21%), Positives = 144/414 (34%), Gaps = 50/414 (12%)

Query: 567 PSTTSPISTRIPH-----RTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAH 621
           PS+  P ST         +T  +P +      L A+T   S      T +SP+S +    
Sbjct: 357 PSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEG 416

Query: 622 GTTL--------NAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSV------PSSPM 667
             T         +  PA SG       + +   SS SS+P+T    SS        S+P+
Sbjct: 417 EPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPV 476

Query: 668 SRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSS 727
              P    ++       +SG+         S           SS    HS  S++   S+
Sbjct: 477 HSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGST 536

Query: 728 SHSMESFRKNCVAHSGPPYPSTVTS---SHSIGLNCVTNKANAVNVRHDQSGRGPPTGSP 784
           +H+  S      A +   Y S++ S   +H    + ++ ++      H        T  P
Sbjct: 537 THTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLP 596

Query: 785 AESIKRMSVMV-NSSDSTLSLGPFIHQSNELP--VNSHGSFSHSHTPLDKLIGKKRKCSP 841
           A S    SV+V +S+ S +S G    ++  LP      G    S T             P
Sbjct: 597 AGSTP--SVLVGDSTPSPISSGSM--ETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLP 652

Query: 842 SSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGA---QGLMNSSLLHQDISSP---CLR 895
           +S + +  S + T     P        HT   PG+    GL   S        P    L 
Sbjct: 653 ASMTSSGVSEESTTSHSRPG-----STHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLS 707

Query: 896 TGISATSPQSPDLK-------SKGTSLTAENSTGRNNADTFEDKLHLHSALWTP 942
            G +  S   P+         S  T+L  +N+T    +   E  + +HS+  +P
Sbjct: 708 PGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTA---SGLLEASMPVHSSTRSP 758



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 174/866 (20%), Positives = 286/866 (33%), Gaps = 147/866 (16%)

Query: 164  SHYERRHSSSSKPP----LAVPPTSVFS--------FFPSLSKSKGGS----ASGSNRSS 207
            SH    H+ SS P     L   PTS  S         FP  S + G S    AS S++ +
Sbjct: 1943 SHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDA 2002

Query: 208  SG----------GVLSASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSRVPHGRIMTPSVK 257
            +G           VL   S++S +     E   L G+T      ++S   H    +P+  
Sbjct: 2003 TGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATT 2062

Query: 258  VEKIHPKMDGTLLKSAVGPTCPATV------SSLVKPGLNCPSIPKPTLPSPGQILNGKG 311
            +        G   +S    + P +        S   PGL+  S    +  SPG   +   
Sbjct: 2063 LSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHS--SPGST-DTTL 2119

Query: 312  LPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCG---VIDLDTKKPCTRSLTCKTH- 367
            LPA  T     ++++ +        S    D  +  G    +    +     S    TH 
Sbjct: 2120 LPASTTTSGPSQESTTSHS------SPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHT 2173

Query: 368  -----SLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTS 422
                 S T    V+                TR       P +   P     P      T+
Sbjct: 2174 TLFPDSTTSSGIVEA--------------STRVHSSTGSPRTTLSPASSTSPGLQGESTA 2219

Query: 423  QEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGC------PAQQGGSAPIDPPPVHES 476
             + H  P     + S P  A+ P   + +  R PG       PA    S   +   +  S
Sbjct: 2220 FQTH--PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHS 2277

Query: 477  PHPPLPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVF 536
              P    T P+S  S+  G G   E +  ++    +     P S  T G  +    +Y  
Sbjct: 2278 S-PDASGTTPSSAHSTTSGRG---ESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSS 2333

Query: 537  D-SRWNRLRCALNLMVEKHLNAQLWKKIP-PVPSTTSPISTRIPHRTNSVPTSQCGVSYL 594
              S    L  A    +     +   +  P    ST SP ST  P           G+S  
Sbjct: 2334 PRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTP-----------GLSEE 2382

Query: 595  AAATVSTSPVLLSSTCISPNSKSVPAHG---TTLNAQPAASGA-MDPVCSMQSRQVSSSS 650
            +    S+SP    +T + P + +    G   TT +++PA++   +    S  S     S+
Sbjct: 2383 STTVYSSSPGSTETT-VFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEEST 2441

Query: 651  SSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKN- 709
            + P +P+  S+    P +     L    +  P  S    T    A S+TSG  G+   + 
Sbjct: 2442 AFPGSPA--STQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSR 2499

Query: 710  ----------------------------SSPLLVHSSSSSSSSSSSSHSMESFRKNCVAH 741
                                        +SP    ++ S ++++SS  S ES      +H
Sbjct: 2500 LSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES----STSH 2555

Query: 742  SGPPYPSTV-----TSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVN 796
            S P    T      T++  +  +  T+ ++  +           T  P++          
Sbjct: 2556 SQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPG 2615

Query: 797  SSDSTLSLGPFIHQS-NELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTK 855
            S+D+ LS G     S  +     H S   +HT L            +S+ +++S+  P +
Sbjct: 2616 STDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP-R 2674

Query: 856  VAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQDISSPCLRTGISATSPQSPDL---KSKG 912
                PA        + T PG QG   +   H   +        +AT+P        +S G
Sbjct: 2675 TTLSPA--------SSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPG 2726

Query: 913  TSLTAENSTGRNNADTFEDKLHLHSA 938
            ++ T         +   E     HS+
Sbjct: 2727 STPTTHFPASSTTSGHSEKSTIFHSS 2752



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 121/576 (21%), Positives = 200/576 (34%), Gaps = 99/576 (17%)

Query: 419  PRTSQEPHQNPHGVIPSESKPFVASKPKPHT-PSLPRPPGCPAQQGGS---APIDPPPVH 474
            PRT+  P  +    +  ES  F       HT PS P     P ++  +   +P   P  H
Sbjct: 2673 PRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTH 2732

Query: 475  ------ESPH----------PPLPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQP 518
                   S H          P    T P+S  S+  G G   E +  ++    +     P
Sbjct: 2733 FPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRG---ESTTSRISPGSTEITTLP 2789

Query: 519  ASFCTFGSRQIGRGYYVFD-SRWNRLRCALNLMVEKHLNAQLWKKIP-PVPSTTSPISTR 576
             S  T G  +    +Y    S    L  A    +     +   +  P    ST SP ST 
Sbjct: 2790 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTT 2849

Query: 577  IPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHG---TTLNAQPAASG 633
             P           G+S  +    S+SP    +T + P S +    G   TT +++PA++ 
Sbjct: 2850 TP-----------GLSEESTTVYSSSPGSTETT-VFPRSTTTSVRGEEPTTFHSRPASTH 2897

Query: 634  A-MDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNC 692
              +    S  S     S++ P +P+  S+    P +     L    +  P  S    T  
Sbjct: 2898 TTLFTEDSTTSGLTEESTAFPGSPA--STQTGLPATLTTADLGEESTTFPSSSGSTGTTL 2955

Query: 693  QNASSSTSGGSGKKRKN-----------------------------SSPLLVHSSSSSSS 723
              A S+TSG  G+   +                             +SP    ++ S ++
Sbjct: 2956 SPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPAT 3015

Query: 724  SSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGS 783
            ++SS  S ES      +HS P    T     S   + ++ +  A    H   G    T S
Sbjct: 3016 TTSSGVSEES----STSHSQPGSTHTTAFPDSTTTSGLSQEPTA---SHSSQGSTEATLS 3068

Query: 784  P----AESIKRMSVMVNSS----------DSTLSLGPFIHQSNELPVNSHGSFSHSHTPL 829
            P    A S+ + S   +SS          D T++ G  + +++    +S GS   + TP 
Sbjct: 3069 PGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSG--LVEASTPTHSSTGSLHTTLTPA 3126

Query: 830  DKLIGKKRKCSPS----SSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLL 885
                   ++ S +     SS + + S P   A    V+  +     + P      +S+ L
Sbjct: 3127 SSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTL 3186

Query: 886  HQDISSPCLRTGISATSPQSPDLKSKGTSLTAENST 921
             +   S  + +   AT       +S  + L  E +T
Sbjct: 3187 GRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTT 3222



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 77/344 (22%), Positives = 130/344 (37%), Gaps = 30/344 (8%)

Query: 568  STTSPISTRIPHRTNS-VPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPA---HGT 623
            STT   S R P  T S   T+  GVS    +T S S    + T   P+S + P    H T
Sbjct: 966  STTFHSSPRSPATTLSPASTTSSGVS--EESTTSRSRPGSTHTTAFPDSTTTPGLSRHST 1023

Query: 624  TLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKL-KSSKSLRP 682
            T ++ P ++       S  +   S  S++  + SG +    SP S       + S +   
Sbjct: 1024 TSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHS 1083

Query: 683  KESSGNSTNCQNASSSTSGGSGKKRKNSS---PLLVHSSSSSSSSSSSSHSMESFRKNCV 739
               S ++T   ++++S+       R +SS   P    S +SS+S      S         
Sbjct: 1084 NPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAS 1143

Query: 740  AHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESI-----KRMSVM 794
             H+ P  PST T+                   H   G  P T  PA S      ++ ++ 
Sbjct: 1144 THTTPSPPSTATA-----------PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF 1192

Query: 795  VNSSDSTLSLGPFIHQSNELPVNSHGS-FSHSHTPLDKLIGKKRK--CSPSSSSINNSSS 851
             +S D++ +     H +      S  S  S   T +  L G       S +S++  +S  
Sbjct: 1193 HSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPR 1252

Query: 852  KPTKVAKVPAVNNVHMKHTGTIPGAQ-GLMNSSLLHQDISSPCL 894
             PT      ++ ++ +    T   +Q G  +S++     ++P L
Sbjct: 1253 SPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL 1296



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 77/322 (23%), Positives = 118/322 (36%), Gaps = 76/322 (23%)

Query: 567  PSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSV---PAH-- 621
            PSTTS +    P   +S P S     +  ++T S      +++  SP++  +   PAH  
Sbjct: 4788 PSTTSALVEE-PTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFT 4846

Query: 622  -------GTTLNAQPA------ASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMS 668
                    TT    P       AS A  P  S +S  + SSS SP      +S+ SS +S
Sbjct: 4847 TSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSIS 4906

Query: 669  RKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSS 728
             +P  L S       ++    T    AS++TSG S            HS   S+ ++ S 
Sbjct: 4907 GEPTSLYS-------QAESTHTTAFPASTTTSGLS------QESTTFHSKPGSTETTLS- 4952

Query: 729  HSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAES- 787
                              P ++T+S         + A      H Q G    T SPA + 
Sbjct: 4953 ------------------PGSITTS---------SFAQEFTTPHSQPGSALSTVSPASTT 4985

Query: 788  ---IKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGS--------FSHSHTPLDKL---I 833
               +   S    SS  +     F H SN + ++S  S        F+H+  P       I
Sbjct: 4986 VPGLSEESTTFYSSPGSTETTAFSH-SNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDI 5044

Query: 834  GKKRKCSPSSSSINNSSSKPTK 855
            G++     SSS    ++  P +
Sbjct: 5045 GQESTAFHSSSDATGTTPLPAR 5066



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 71/351 (20%), Positives = 125/351 (35%), Gaps = 51/351 (14%)

Query: 570  TSPISTRI---PHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLN 626
            T P ST     P  T + P  +    + +  +  T+    SST    + KS     T  +
Sbjct: 3779 THPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKS-----TIFH 3833

Query: 627  AQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESS 686
            + P ASG         +     S++S  +P G + + + P S     L  + +       
Sbjct: 3834 SSPDASGTTPSSAHSTTSGRGESTTSRISP-GSTEITTLPGSTTTPGLSEASTTFYSSPR 3892

Query: 687  GNSTNCQNASSSTSG-GSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPP 745
              +T    AS ++ G G       S P   HS+ S +S+++   S ES       +S  P
Sbjct: 3893 SPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEES----TTVYSSSP 3948

Query: 746  YPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLG 805
              +  T         V  ++   +VR ++     PT   +      + +     +T  L 
Sbjct: 3949 GSTETT---------VFPRSTTTSVRREE-----PTTFHSRPASTHTTLFTEDSTTSGLT 3994

Query: 806  PFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVA-------K 858
                     P ++      + T  D  +G++    PSSS    +   P +          
Sbjct: 3995 EESTAFPGSPASTQTGLPATLTTAD--LGEESTTFPSSSGSTGTKLSPARSTTSGLVGES 4052

Query: 859  VPAVNNVHMKHTGTIPGAQGLMNSSLLHQDISSPCL--RTGISATSPQSPD 907
             P+  +     T T+PG+             ++P L  ++    TSP+SPD
Sbjct: 4053 TPSRLSPSSTETTTLPGSP------------TTPSLSEKSTTFYTSPRSPD 4091



 Score = 34.7 bits (78), Expect = 0.43
 Identities = 78/367 (21%), Positives = 126/367 (34%), Gaps = 51/367 (13%)

Query: 613  PNSK-SVPAHGTT------LNAQPAASGAMDPVCSMQSRQVSSSSSSPST-----PSGLS 660
            PNSK + PA  TT      L+     S +  P     +   +   S  ST     P   +
Sbjct: 4476 PNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 4535

Query: 661  SVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSS 720
            + PS   S     ++ S +     S G++       S+T+ G G++   S     HSS++
Sbjct: 4536 TTPSPARSTTSGLVEESTTYH--SSPGSTQTMHFPESNTTSGRGEESTTS-----HSSTT 4588

Query: 721  SSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGR--- 777
             + SS+ S +     +    HS P   +T     S   +  + ++ A +   D +G    
Sbjct: 4589 HTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVL 4648

Query: 778  ----------GPPTGSPAESIKRMSVMVNSSDSTLSL---GPFIHQSNELPVNSHGSFSH 824
                      G  T SP  S    +  +  S +T  L       H S      +H  FS 
Sbjct: 4649 PARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTH--FSA 4706

Query: 825  SHTPLDKL----------IGKKRKCSPSSSSINNSSSKPTKVAKVP-AVNNVHMKHTGTI 873
            S T L +           +      SP+ S+ +    + T     P +   +H   + T 
Sbjct: 4707 SSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTA 4766

Query: 874  PG--AQGLMNSSLLHQDISSPCLRTGISATSPQSPDLKSKGTSLTAENSTGRNNADTFED 931
             G   +   + S     ISSP   T      P S    S G+  T         +   E+
Sbjct: 4767 SGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYH-SSPGSIATTHFPESSTTSGRSEE 4825

Query: 932  KLHLHSA 938
                HS+
Sbjct: 4826 STASHSS 4832



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 39/168 (23%), Positives = 65/168 (38%), Gaps = 10/168 (5%)

Query: 570  TSPISTRI---PHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLN 626
            T P ST     P  T + P  +    + +  +  T+    SST    + KS     T  +
Sbjct: 1139 THPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKS-----TIFH 1193

Query: 627  AQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESS 686
            + P ASG         +     S++S  +P G + + + P S     L  + +       
Sbjct: 1194 SSPDASGTTPSSAHSTTSGRGESTTSRISP-GSTEITTLPGSTTTPGLSEASTTFYSSPR 1252

Query: 687  GNSTNCQNASSSTSG-GSGKKRKNSSPLLVHSSSSSSSSSSSSHSMES 733
              +T    AS ++ G G       S P   HS+ S +S+++   S ES
Sbjct: 1253 SPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEES 1300



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 75/357 (21%), Positives = 126/357 (35%), Gaps = 56/357 (15%)

Query: 613  PNSK-SVPAHGTT------LNAQPAASGAMDPVCSMQSRQVSSSSSSPST-----PSGLS 660
            PNSK + PA  TT      L+     S +  P     +   +   S  ST     P   +
Sbjct: 3393 PNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 3452

Query: 661  SVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSS 720
            + PS   S     ++ S +     S G++       S T+ G G++   S     HSS++
Sbjct: 3453 TTPSPARSTTSGLVEESTTYH--SSPGSTQTMHFPESDTTSGRGEESTTS-----HSSTT 3505

Query: 721  SSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGR--- 777
             + SS+ S +     +    HS P   +T     S   +  + ++ A +   D +G    
Sbjct: 3506 HTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVL 3565

Query: 778  ----------GPPTGSPAESIKRMSVMVNSSDSTLSL---GPFIHQSNELPVN--SHGSF 822
                      G  T SP  S    +  +  S +T  L       H S   P    S  S 
Sbjct: 3566 PARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPAST 3625

Query: 823  SHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNS 882
            + S    +      R  S  +++  +S++ P              +H+ T   + G  ++
Sbjct: 3626 TSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGL-----------SRHSTTSHSSPGSTDT 3674

Query: 883  SLLHQDISSPCLRTGISATSPQSPDLKSKGTSLTAENSTGRNNADTF-EDKLHLHSA 938
            +LL          T  S +S +S    S   S     S G   A +F ++    HS+
Sbjct: 3675 TLLPAS-------TTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSS 3724



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 72/330 (21%), Positives = 117/330 (35%), Gaps = 67/330 (20%)

Query: 622 GTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLR 681
           G  L+ Q  A+GA +       ++   +  + ST SG S +  S ++             
Sbjct: 131 GLPLSEQARAAGARE-------KERQETVINHSTFSGFSQITGSTVNTS----------- 172

Query: 682 PKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSS---SSSSSSSHSMESFRKNC 738
                GN+T+    SSS    +      S   +  S+++     SS++S HS ES     
Sbjct: 173 ---IGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEES----T 225

Query: 739 VAHSGP-PYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNS 797
           V+HSGP    +T+  SHS         A +V V       G P  SP  S    +  +  
Sbjct: 226 VSHSGPGATGTTLFPSHS---------ATSVFV-------GEPKTSPITSASMETTALPG 269

Query: 798 SDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVA 857
           S +T  L             S   +S   +P        R  SP+ ++ +  S K T   
Sbjct: 270 STTTAGLSE----------KSTTFYSSPRSP-------DRTLSPARTTSSGVSEKSTTSH 312

Query: 858 KVPA-VNNVHMKHTGTIPGAQGLMNSSLLHQDISSPCLRTGISATSPQSPDL----KSKG 912
             P   + +    + T+PG      +S      +   L  G +  S   P+      S G
Sbjct: 313 SRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPG 372

Query: 913 TSLTAENSTGRNNADTFEDKLHLHSALWTP 942
            + T         +   E    +HS+  +P
Sbjct: 373 YTKTTRLPDNTTTSGLLEASTPVHSSTGSP 402



 Score = 32.0 bits (71), Expect = 2.8
 Identities = 118/571 (20%), Positives = 184/571 (32%), Gaps = 131/571 (22%)

Query: 421  TSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPP 480
            T   P ++    +  ES P   S     T +LP  P  P+    S        + SP  P
Sbjct: 1396 TKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTF-----YTSPRSP 1450

Query: 481  LPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRW 540
                 PA+  SS    G  +E S           H QP S  T                 
Sbjct: 1451 DATLSPATTTSS----GVSEESSTS---------HSQPGSTHT----------------- 1480

Query: 541  NRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVS 600
                       +    + L ++  P  S +S  ST       S   S  G     + T  
Sbjct: 1481 -------TAFPDSTTTSDLSQE--PTTSHSSQGSTEATLSPGSTTASSLGQQ---STTFH 1528

Query: 601  TSPVLLSSTCISPNS-------KSVPAHGTTLNAQPAASGAMDPVCSMQSRQV------S 647
            +SP    +T +  ++        S P H +T +     + A      +Q          S
Sbjct: 1529 SSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPS 1588

Query: 648  SSSSSPSTP--------------SGLSSVPSSPMSRKPQKLKSSK--------------- 678
            SS ++PS P              S  SS P++  S     L  S+               
Sbjct: 1589 SSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTA 1648

Query: 679  ---------------SLRPKESSGNSTNCQNASSSTSGGSGKKRK-NSSPLLVHSSSSSS 722
                           +  P  S    T     S++T+G S K     SSP    ++ S +
Sbjct: 1649 LFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPA 1708

Query: 723  SSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTG 782
            S++SS  S ES      +HS P    T     S  +  V+ ++ A    H   G    T 
Sbjct: 1709 STTSSGVSEES----TTSHSRPGSTHTTAFPGSTTMPGVSQESTA---SHSSPGSTDTTL 1761

Query: 783  SPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNS------------HGSFSHSHTPLD 830
            SP  +    +  +    +T    P   ++  LP N+            H S    HT L 
Sbjct: 1762 SPGST---TASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLS 1818

Query: 831  KLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQDIS 890
               G   +   S++  +  SSK T  A  P   +  ++ + T  G+    ++   H   S
Sbjct: 1819 P-AGSTTRQGESTTFQSWPSSKDTMPAP-PTTTSAFVELSTTSHGSPS--STPTTHFSAS 1874

Query: 891  SPCLRTGISATSPQSPDLKSKGTSLTAENST 921
            S  L     +T+  S  + +  T   A ++T
Sbjct: 1875 STTLGRSEESTTVHSSPVATATTPSPARSTT 1905



 Score = 31.6 bits (70), Expect = 3.7
 Identities = 56/227 (24%), Positives = 95/227 (41%), Gaps = 29/227 (12%)

Query: 601  TSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS 660
            TS ++ +ST    ++ S+  H T   A   ++G  +   + QS   SSS ++PS PS  +
Sbjct: 4185 TSGLVEASTPTHSSTGSL--HTTLTPASSTSTGLQEESTTFQSWP-SSSDTTPSPPS-TT 4240

Query: 661  SVP---SSPMSRKPQKLKS---SKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLL 714
            +VP   S+    +P    +   S S      S  ST   ++  +T       R  +S L+
Sbjct: 4241 AVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLV 4300

Query: 715  VHSSSSSSSSSS--------SSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKAN 766
               ++S  SS S        S+ +     K+   +S P  P T  S  S   + V+ ++ 
Sbjct: 4301 GEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEES- 4359

Query: 767  AVNVRHDQSGRGPPTGSPAES----IKRMSVMVNSS----DSTLSLG 805
                 H + G    T  P+ +    + + S   +SS    D+TLS G
Sbjct: 4360 --TTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPG 4404


>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
          Length = 3571

 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 54/195 (27%), Positives = 70/195 (35%), Gaps = 18/195 (9%)

Query: 293  PSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLS-EREFDPDIHCGVID 351
            PSIP P + S  +    K L      E   + N N +K   K  S E E    + CG   
Sbjct: 1848 PSIPPPRIASGARGNAAKALLENFGFELVIQYNENRQKVQKKGKSGEGENTDKLECGTCG 1907

Query: 352  LDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVL--LAEHKNKTREKELIRHPDSQQPPQ 409
                K  +  L  K+H    +  V G+   +  L   A    +  +K     P S + P 
Sbjct: 1908 ----KLFSNVLILKSH----QEHVHGQFFPYAALEKFARQYREAYDKLYPISPSSPETPP 1959

Query: 410  PLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPID 469
            P   P P PP   Q     P  +  + S P  A  P P  P  P PP  P       P  
Sbjct: 1960 PPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPP-------PPP 2012

Query: 470  PPPVHESPHPPLPAT 484
            PPP    P   LP +
Sbjct: 2013 PPPPSAPPQVQLPVS 2027



 Score = 38.1 bits (87), Expect = 0.039
 Identities = 16/32 (50%), Positives = 21/32 (65%)

Query: 30   QQQQQQQQQQPPPPQPQRQQHPPPPPRRTRPE 61
            QQQ QQ Q   P  QPQ+QQ  PPPP++ + +
Sbjct: 1752 QQQAQQYQATQPQLQPQKQQQQPPPPQQQQQQ 1783



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 16/24 (66%), Positives = 18/24 (75%)

Query: 26   AAARQQQQQQQQQQPPPPQPQRQQ 49
            A   Q Q Q+QQQQPPPPQ Q+QQ
Sbjct: 1760 ATQPQLQPQKQQQQPPPPQQQQQQ 1783



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 20/84 (23%), Positives = 37/84 (44%), Gaps = 5/84 (5%)

Query: 7    DDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQ---RQQHPPPPPRRTRPEDG 63
            D  +     AA++  G +       + + ++  P P  P    +Q  P PP + T+P   
Sbjct: 2326 DAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKP--A 2383

Query: 64   GPGAASTSAAAMATVGERRPLPSP 87
             P A+++S    A+  + +P P P
Sbjct: 2384 LPLASTSSDPPQASTAQPQPQPQP 2407



 Score = 31.6 bits (70), Expect = 3.7
 Identities = 14/25 (56%), Positives = 17/25 (68%)

Query: 25   AAAARQQQQQQQQQQPPPPQPQRQQ 49
            A   + Q Q+QQQQ PPP Q Q+QQ
Sbjct: 1760 ATQPQLQPQKQQQQPPPPQQQQQQQ 1784



 Score = 31.2 bits (69), Expect = 4.8
 Identities = 24/75 (32%), Positives = 29/75 (38%), Gaps = 15/75 (20%)

Query: 414  PHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPV 473
            P P P +TS +P              + A KPK   PS P     PA    S   DPP  
Sbjct: 2350 PKPEPEKTSPKPE-------------YPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQA 2396

Query: 474  HES-PHP-PLPATEP 486
              + P P P P  +P
Sbjct: 2397 STAQPQPQPQPPKQP 2411



 Score = 30.8 bits (68), Expect = 6.2
 Identities = 17/43 (39%), Positives = 21/43 (48%)

Query: 459  PAQQGGSAPIDPPPVHESPHPPLPATEPASRLSSEEGEGDDKE 501
            PA    SAP  P      P PP P   P+S LS ++ E  +KE
Sbjct: 3101 PALSLSSAPTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKE 3143


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 58/257 (22%), Positives = 100/257 (38%), Gaps = 28/257 (10%)

Query: 568  STTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNA 627
            +TT+  +  +   ++S  TS    S +  AT  T+    ++   +P +  +P   TT   
Sbjct: 3925 TTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTAT 3984

Query: 628  QPAA-SGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMS-RKPQKLKSSKSLRPKES 685
             PAA S  + P  ++ +       ++ +T  G S  PSSP + R      +S +L     
Sbjct: 3985 TPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHI 4044

Query: 686  SGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPP 745
            +  ST   +  ++T+G +            HS+ + SS   SS + ES          PP
Sbjct: 4045 TEPSTGTSHTPAATTGTTQ-----------HSTPALSSPHPSSRTTES----------PP 4083

Query: 746  YPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLG 805
             P T T  H+   +  T  A     R        PT +P       +V+    +   +  
Sbjct: 4084 SPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPI-----TTVVTTGCEPQCAWS 4138

Query: 806  PFIHQSNELPVNSHGSF 822
             ++  S  +P  S G F
Sbjct: 4139 EWLDYSYPMPGPSGGDF 4155



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 59/278 (21%), Positives = 104/278 (37%), Gaps = 31/278 (11%)

Query: 564  PPV-PSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKS----- 617
            PPV  STT+  +TR    +   P+S  G ++ A    +T+  + + +  +P+S +     
Sbjct: 3333 PPVWISTTTTPTTR---GSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGT 3389

Query: 618  ----------VPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPM 667
                      + A G+T N          P     +    +++SS  TPS       +P 
Sbjct: 3390 PPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPP 3449

Query: 668  SRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSS 727
                      +SL P       T   +A+S   G +      + P  V S + ++++S++
Sbjct: 3450 VPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTT----HITEPSTVTSHTPAATTSTT 3505

Query: 728  SHS---MESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSP 784
             HS   + S   +      PP P T T  H+ G +  T  A     R        PT +P
Sbjct: 3506 QHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAP 3565

Query: 785  AESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSF 822
                   +V+    +   +   ++  S  +P  S G F
Sbjct: 3566 I-----TTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDF 3598



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 53/226 (23%), Positives = 89/226 (39%), Gaps = 23/226 (10%)

Query: 568  STTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNA 627
            +TT+  +  +   ++S  TS    S    AT  T+    ++   +P +  +P   TT   
Sbjct: 2668 TTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTAT 2727

Query: 628  QPAA-SGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMS-RKPQKLKSSKSLRPKES 685
             PAA S  + P  ++ +       ++ +T  G S  PSSP + R      +S +L     
Sbjct: 2728 TPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHI 2787

Query: 686  SGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPP 745
            +  ST   +  ++T+G +            HS+ + SS   SS + ES          PP
Sbjct: 2788 TEPSTGTSHTPAATTGTTQ-----------HSTPALSSPHPSSRTTES----------PP 2826

Query: 746  YPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRM 791
             P T T  H+   +  T  A     R        PT +P  ++  M
Sbjct: 2827 SPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTM 2872



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 53/226 (23%), Positives = 88/226 (38%), Gaps = 23/226 (10%)

Query: 568  STTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNA 627
            +TT+  +  +   ++S  TS    S    AT  T+    ++   +P +  +P   TT   
Sbjct: 2111 TTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTAT 2170

Query: 628  QPAA-SGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMS-RKPQKLKSSKSLRPKES 685
             PAA S  + P  ++ +       ++ +T  G S  PSSP + R      +S  L     
Sbjct: 2171 TPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHI 2230

Query: 686  SGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPP 745
            +  ST   +  ++T+G +            HS+ + SS   SS + ES          PP
Sbjct: 2231 TEPSTVTSHTLAATTGTTQ-----------HSTPALSSPHPSSRTTES----------PP 2269

Query: 746  YPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRM 791
             P T T  H+   +  T  A     R        PT +P  ++  M
Sbjct: 2270 SPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTM 2315



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 76/406 (18%), Positives = 143/406 (35%), Gaps = 69/406 (16%)

Query: 567  PSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTL- 625
            P T  P        T    TS    S  +  T +T PVL S+   S  +   P    TL 
Sbjct: 3019 PGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLG 3078

Query: 626  ---------NAQPAASGAMDPVCSMQSRQVS-------------SSSSSPSTPSGLSSVP 663
                         A    + P  + ++   S             SS S+PS+  G + + 
Sbjct: 3079 TTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWIL 3138

Query: 664  SSPMSRKPQKLKSSKSLRPKESSGNS---------------TNCQNASSSTSGGSGKKRK 708
            +   +       +  +  P  + G +               T     +SST   +G  + 
Sbjct: 3139 TELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKV 3198

Query: 709  NSS----PLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNK 764
             +S    P ++ S ++ SSS  ++ ++ + R         P  ++VT+  S  L     +
Sbjct: 3199 LTSTATTPTVISSRATPSSSPGTATALPALRSTATT----PTATSVTAIPSSSLGTAWTR 3254

Query: 765  ANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSH 824
             +             P+ +P E++   +V+  ++ +T + G     S   P ++ G+   
Sbjct: 3255 LSQTTTPTATMSTATPSSTP-ETVHTSTVLTTTTTTTRATG-----SVATPSSTPGTAHT 3308

Query: 825  SHTPLDKLIGKKRKCSPSSSS---------INNSSSKPTKVAKVPAVNNVHMKHTGTIPG 875
            +  P     G     +PSSS          I+ +++  T+ + V   +     HT T+  
Sbjct: 3309 TKVPTTTTTG--FTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATV-- 3364

Query: 876  AQGLMNSSLLHQDISSPCLRTGISATSPQSPDLKSKGTSLTAENST 921
                + ++       S    +  + TS   P L +  T++TA  ST
Sbjct: 3365 ----LTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGST 3406



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 73/370 (19%), Positives = 139/370 (37%), Gaps = 49/370 (13%)

Query: 564  PPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT 623
            PP    TSP +T  P  T+S  TS       +  T +T PVL S+   S  +   P   +
Sbjct: 4280 PPPKVLTSPATT--PTATSSKATSSS-----SPRTATTLPVLTSTATKSTATSVTPIPSS 4332

Query: 624  TLNAQ-PAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRP 682
            TL            PV +M +   SS+  +  T + L++  ++  +       +S +  P
Sbjct: 4333 TLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRA-------TSSTSTP 4385

Query: 683  KESSGNS---TNCQNASSSTSGGSGKKRKNSSP----LLVHSSSSSSSSSSSSHSMESFR 735
              + G +   T    A+++T+        +S+P    +L   ++++++++S+        
Sbjct: 4386 SSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTG------- 4438

Query: 736  KNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPP---TGSPAESIKRMS 792
             +    S  P  + + +  S          +       Q+  G P   T +   ++    
Sbjct: 4439 -STATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSK 4497

Query: 793  VMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSS-SINNSSS 851
               +SS  T +  P +  +   P     + S +  P   L     + S +++ +   S++
Sbjct: 4498 ATPSSSPGTATALPALRSTATTPT----ATSFTAIPSSSLGTTWTRLSQTTTPTATMSTA 4553

Query: 852  KPTKVAKVPAVNNVHMKHTGTIPGAQGLM-----NSSLLHQDISSPCLRTGISATSPQSP 906
             P+   +    + V +  T T  GA G +          H         TG +AT   SP
Sbjct: 4554 TPSSTPETVHTSTV-LTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSP 4612

Query: 907  DLKSKGTSLT 916
                 GT+LT
Sbjct: 4613 -----GTALT 4617



 Score = 35.0 bits (79), Expect = 0.33
 Identities = 36/183 (19%), Positives = 80/183 (43%), Gaps = 13/183 (7%)

Query: 555  LNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPN 614
            L   +W      P+TT+P ++      +S+P    G ++ A    +T+  + + +  +P+
Sbjct: 4616 LTPPVWISTTTTPTTTTPTTSGSTVTPSSIP----GTTHTARVLTTTTTTVATGSMATPS 4671

Query: 615  SK-----SVPAHGTTLNAQPAASGAMDPVCSMQSRQVSS-SSSSPSTPSGLSSVPSSPMS 668
            S      + P+  TT     A     +P  +  +  ++   +S+ +TP+  SS  +S  S
Sbjct: 4672 SSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATS--S 4729

Query: 669  RKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGK-KRKNSSPLLVHSSSSSSSSSSS 727
              P+   +   L    +   +T+     SST   +     + ++P+   S+  +SS+  +
Sbjct: 4730 SSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPET 4789

Query: 728  SHS 730
            +H+
Sbjct: 4790 THT 4792



 Score = 33.5 bits (75), Expect = 0.96
 Identities = 60/347 (17%), Positives = 132/347 (38%), Gaps = 27/347 (7%)

Query: 581  TNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT-TLNAQPAASGAMDPVC 639
            T +  T+  G +   ++T  T+ +L   +  +  + +VP   T T ++  A +G      
Sbjct: 4429 TTATTTASTGSTATPSSTPGTTWILTEPSTTA--TVTVPTGSTATASSTQATAGTPHVST 4486

Query: 640  SMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSST 699
            +  +  V+SS ++PS+  G ++   +  S       +S +  P  S G +    + +++ 
Sbjct: 4487 TATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTP 4546

Query: 700  SGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLN 759
            +        +S+P  VH+S+  +++++++ +  S      +  G  + + V ++ + G  
Sbjct: 4547 TATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPS-STPGTAHTTKVPTTTTTGFT 4605

Query: 760  CVTNKANAVNVRHDQSGRGPPTGSPAESIKR---MSVMVNSSDSTLSLGPFIHQSNELPV 816
                                P+ SP  ++     +S     + +T +        + +P 
Sbjct: 4606 AT------------------PSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPG 4647

Query: 817  NSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHT--GTIP 874
             +H +   + T      G     S S+ +     S  T    + A  +     +  GT P
Sbjct: 4648 TTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTP 4707

Query: 875  GAQGLMNSSLLHQDISSPCLRTGISATSPQSPDLKSKGTSLTAENST 921
                L +++      SS    +    T+   P L S  T  TA + T
Sbjct: 4708 ITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFT 4754



 Score = 31.2 bits (69), Expect = 4.8
 Identities = 33/175 (18%), Positives = 76/175 (43%), Gaps = 15/175 (8%)

Query: 567  PSTTSPISTRIPHRT------------NSVPTSQCGVSYLAAATVSTSPVLLSSTCISPN 614
            PST +  ST +P  T             +  T   G +   ++T  T+ +L   +  +  
Sbjct: 2418 PSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTA-- 2475

Query: 615  SKSVPAHGT-TLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQK 673
            + +VP   T T ++  A +G      +  +  V+SS ++P +  G ++   +  S     
Sbjct: 2476 TVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTP 2535

Query: 674  LKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSS 728
              +S +  P  S G +    + +++ +        +S+P  VH+S+  +++++++
Sbjct: 2536 TATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTT 2590



 Score = 30.8 bits (68), Expect = 6.2
 Identities = 36/164 (21%), Positives = 71/164 (43%), Gaps = 21/164 (12%)

Query: 567  PSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLN 626
            PST +  ST       + P+S  G +++      T P   ++T  S  S + P   +TL 
Sbjct: 1889 PSTPATSST-------ATPSSTPGTTWIL-----TKPTTTATTTASTGSTATPT--STLR 1934

Query: 627  AQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESS 686
              P          +  +  V+SS ++PS+  G ++  + P  R      ++ S+ P  SS
Sbjct: 1935 TAPPPKVL---TTTATTPTVTSSKATPSSSPGTAT--ALPALRSTATTPTATSVTPIPSS 1989

Query: 687  GNSTNCQNASSST--SGGSGKKRKNSSPLLVHSSSSSSSSSSSS 728
               T     S +T  +        +S+P   H+S+  +++++++
Sbjct: 1990 SLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTT 2033



 Score = 30.4 bits (67), Expect = 8.1
 Identities = 33/177 (18%), Positives = 76/177 (42%), Gaps = 9/177 (5%)

Query: 564  PPVPSTTSPISTR------IPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKS 617
            P   ST +P ST           T +  T   G +   ++T  T+ +L   +  +  + +
Sbjct: 3678 PATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTA--TVT 3735

Query: 618  VPAHGT-TLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKS 676
            VP   T T ++  A +G      +  +  V+SS ++P +  G ++   +  S       +
Sbjct: 3736 VPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTAT 3795

Query: 677  SKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMES 733
            S +  P  S G +    + +++ +        +S+P   H+S+  +++++++ +  S
Sbjct: 3796 SFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGS 3852


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.125    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,697,255
Number of Sequences: 37866
Number of extensions: 2948045
Number of successful extensions: 46815
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 581
Number of HSP's successfully gapped in prelim test: 1308
Number of HSP's that attempted gapping in prelim test: 22620
Number of HSP's gapped (non-prelim): 17985
length of query: 945
length of database: 18,247,518
effective HSP length: 112
effective length of query: 833
effective length of database: 14,006,526
effective search space: 11667436158
effective search space used: 11667436158
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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