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Search of human proteins with 189011592
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|189011592 amyotrophic lateral sclerosis 2 (juvenile)
chromosome region, candidate 12 isoform b [Homo sapiens]
(422 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|189011592 amyotrophic lateral sclerosis 2 (juvenile) chromoso... 843 0.0
gi|189011586 amyotrophic lateral sclerosis 2 (juvenile) chromoso... 830 0.0
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 69 6e-12
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 68 1e-11
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 68 2e-11
gi|71061468 centromere protein E [Homo sapiens] 65 9e-11
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 65 2e-10
gi|34577114 cytomatrix protein p110 [Homo sapiens] 64 3e-10
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 61 2e-09
gi|221219020 NYD-SP11 protein [Homo sapiens] 61 2e-09
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 60 3e-09
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 60 3e-09
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 60 3e-09
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 60 3e-09
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 60 3e-09
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 60 4e-09
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens] 60 5e-09
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 59 6e-09
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 59 6e-09
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 59 6e-09
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 59 8e-09
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] 59 8e-09
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 59 1e-08
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 59 1e-08
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 59 1e-08
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 59 1e-08
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 58 1e-08
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 58 1e-08
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof... 58 1e-08
gi|156104908 myosin heavy chain 6 [Homo sapiens] 58 2e-08
>gi|189011592 amyotrophic lateral sclerosis 2 (juvenile) chromosome
region, candidate 12 isoform b [Homo sapiens]
Length = 422
Score = 843 bits (2179), Expect = 0.0
Identities = 422/422 (100%), Positives = 422/422 (100%)
Query: 1 MYPNPLIYCTCWDPWNLGPRKLIKTPQLPRKNSTGSSKLTPLVPAPKNHNYLQPTKPVVS 60
MYPNPLIYCTCWDPWNLGPRKLIKTPQLPRKNSTGSSKLTPLVPAPKNHNYLQPTKPVVS
Sbjct: 1 MYPNPLIYCTCWDPWNLGPRKLIKTPQLPRKNSTGSSKLTPLVPAPKNHNYLQPTKPVVS 60
Query: 61 PKMKIHSARQEETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIPDKGR 120
PKMKIHSARQEETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIPDKGR
Sbjct: 61 PKMKIHSARQEETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIPDKGR 120
Query: 121 FSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEA 180
FSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEA
Sbjct: 121 FSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEA 180
Query: 181 HEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQK 240
HEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQK
Sbjct: 181 HEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQK 240
Query: 241 AKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQ 300
AKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQ
Sbjct: 241 AKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQ 300
Query: 301 SDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFA 360
SDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFA
Sbjct: 301 SDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFA 360
Query: 361 ETEEKYKHTIQILTEENIHLKQKIISKNEEICEGCSGRLASITVSKDDSDTVQDGSKKGQ 420
ETEEKYKHTIQILTEENIHLKQKIISKNEEICEGCSGRLASITVSKDDSDTVQDGSKKGQ
Sbjct: 361 ETEEKYKHTIQILTEENIHLKQKIISKNEEICEGCSGRLASITVSKDDSDTVQDGSKKGQ 420
Query: 421 ES 422
ES
Sbjct: 421 ES 422
>gi|189011586 amyotrophic lateral sclerosis 2 (juvenile) chromosome
region, candidate 12 isoform a [Homo sapiens]
Length = 445
Score = 830 bits (2145), Expect = 0.0
Identities = 422/445 (94%), Positives = 422/445 (94%), Gaps = 23/445 (5%)
Query: 1 MYPNPLIYCTCWDPWNLGPRKLIKTPQLPRKNSTGSSKLTPLVPAPKNHNYLQPTKPVVS 60
MYPNPLIYCTCWDPWNLGPRKLIKTPQLPRKNSTGSSKLTPLVPAPKNHNYLQPTKPVVS
Sbjct: 1 MYPNPLIYCTCWDPWNLGPRKLIKTPQLPRKNSTGSSKLTPLVPAPKNHNYLQPTKPVVS 60
Query: 61 PKMKIHSARQEETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIPDKGR 120
PKMKIHSARQEETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIPDKGR
Sbjct: 61 PKMKIHSARQEETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIPDKGR 120
Query: 121 FSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEA 180
FSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEA
Sbjct: 121 FSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEA 180
Query: 181 HEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQK 240
HEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQK
Sbjct: 181 HEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQK 240
Query: 241 AKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQ 300
AKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQ
Sbjct: 241 AKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQ 300
Query: 301 SDTLQLEELRKTKE-----------------------VMQEELHAQALILESLNTNLYYT 337
SDTLQLEELRKTKE VMQEELHAQALILESLNTNLYYT
Sbjct: 301 SDTLQLEELRKTKEVPWRRDQINRHWHDVLQQLLLMQVMQEELHAQALILESLNTNLYYT 360
Query: 338 QLELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEICEGCSG 397
QLELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEICEGCSG
Sbjct: 361 QLELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEICEGCSG 420
Query: 398 RLASITVSKDDSDTVQDGSKKGQES 422
RLASITVSKDDSDTVQDGSKKGQES
Sbjct: 421 RLASITVSKDDSDTVQDGSKKGQES 445
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 69.3 bits (168), Expect = 6e-12
Identities = 54/268 (20%), Positives = 133/268 (49%), Gaps = 9/268 (3%)
Query: 130 LEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELE 189
+E + SE+ ++++ R + A KLL + L+ E ++ K + E +EL
Sbjct: 233 VESEKSEIQLNVKELKRKLERA-KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELW 291
Query: 190 NNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKF 249
N + + +EK++E ++ + + R ++ I ++ E+ +++ W+K+EK
Sbjct: 292 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 351
Query: 250 ERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFE-NFIQEKEELLKQHQSDTLQLEE 308
R+ ++ +K++ ++ E E+++KI E + E I+E+EE K+ + + ++ +E
Sbjct: 352 RRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEE--KRQEEEKIREQE 409
Query: 309 LRKTKEV----MQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAETEE 364
R+ +E +E++ Q + ++ + ++ +++ I ++ Q + EE
Sbjct: 410 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 469
Query: 365 KYKHTIQILTE-ENIHLKQKIISKNEEI 391
K + +I + E +H ++KI + E++
Sbjct: 470 KIREQEEIWRQKEKMHEQEKIRKQEEKV 497
Score = 63.9 bits (154), Expect = 3e-10
Identities = 66/305 (21%), Positives = 139/305 (45%), Gaps = 43/305 (14%)
Query: 102 DEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSA------QKLL 155
+EM K+ E+ +K I + EE+ E I EQ R Q A +K+
Sbjct: 369 EEMMWEKEEKIRELEEK--MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 426
Query: 156 SSEMDLRCAEMKQ-------------NFENKNRELKEA--HEAELSELENNYKAALKAEK 200
E +R E K E K +E +E E ++ E E ++ + EK
Sbjct: 427 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR---QKEK 483
Query: 201 LAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKK 260
+ QEK+ + ++ + ++ I ++ E+ W +++ +++EK + +++++
Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE 543
Query: 261 KMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEEL 320
+M ++ E + GE+++K +QE+E++ +Q + Q E++R+ KE ++E+
Sbjct: 544 EMMQEQEEKMGEQEEK------------MQEQEKMRRQEEKIREQEEKIREQKEKIREQ- 590
Query: 321 HAQALILESLNTNLYYTQLELQKEKAIVGNLEKML--QTKFAETEEKYKHTIQILTEENI 378
+ I E ++ ++E+ + EKM + K E EEK + + + E+ +
Sbjct: 591 --EEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 648
Query: 379 HLKQK 383
L+Q+
Sbjct: 649 RLRQQ 653
Score = 52.4 bits (124), Expect = 8e-07
Identities = 64/294 (21%), Positives = 129/294 (43%), Gaps = 40/294 (13%)
Query: 53 QPTKPVVSPKMKIHSARQEETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKK--- 109
Q K K++ RQE+ K + + + + +R +E+ +++ +++K
Sbjct: 395 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 454
Query: 110 -----------RWESEIPDKGRFSRTNIISDLEEQI-SELTAIIEQMNRDHQSAQKLLSS 157
R E +I ++ R +E+I + + Q + H +K+
Sbjct: 455 EEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQ 514
Query: 158 EMDL-RCAEMKQNFENKNRELKEA-HEAELSELENNYKAALKAEKLAAQEKLEEMGKEYK 215
E + R E + E K RE +E E E E K + EK+ QEK+
Sbjct: 515 EEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQ----- 569
Query: 216 YLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKF-ERENILLQQKKKMTKKFEMESGEED 274
+ R ++ I ++ E+ +++ W+++EK E+E ++ +Q++KM ++ E +E+
Sbjct: 570 --EEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 627
Query: 275 KKINESCSAVFENFIQEKEELLKQHQSDTLQLE-ELRKTKEVMQE-ELHAQALI 326
K +QE+EE +++ + + E LR+ +E MQE + H +A I
Sbjct: 628 K-------------MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 68.2 bits (165), Expect = 1e-11
Identities = 77/382 (20%), Positives = 169/382 (44%), Gaps = 35/382 (9%)
Query: 20 RKLIKTPQLPRKNSTGSSKLTPLVPAPKNHNYLQPTKPVVSPKMKIHSAR--------QE 71
R I +L KN+ KL LV + K+ L V K K+ A+ Q
Sbjct: 199 RNTITDEELKEKNAKLQEKLQ-LVESEKSEIQLN----VKELKRKLERAKLLLPQQQLQA 253
Query: 72 ETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDLE 131
E + E+ +VS Q ++ L + ++ R E +I + R I + E
Sbjct: 254 EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE-----REEKIQEQE 308
Query: 132 EQISELTAII--------EQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEA 183
E+I E + E+ + + + + E +R E K + + K RE +E +
Sbjct: 309 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 368
Query: 184 ELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKW 243
E E + +A+ +EK+ E ++ + + M + ++ + ++ E+ W +++
Sbjct: 369 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQ 428
Query: 244 KKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDT 303
+++EK R+ +++++K ++ E + E+++ + E E +++ ++ +Q
Sbjct: 429 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ----EEKMGEQEGKMCEQEAKMQ 484
Query: 304 LQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKML--QTKFAE 361
Q E++R+ +E ++E+ + I E ++ ++E+ + EKM + K E
Sbjct: 485 EQEEKMRRQEEKIREQ---EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541
Query: 362 TEEKYKHTIQILTEENIHLKQK 383
EEK + + + E+ + L+Q+
Sbjct: 542 QEEKMRRQEEKMREQEVRLRQQ 563
Score = 54.7 bits (130), Expect = 2e-07
Identities = 64/238 (26%), Positives = 111/238 (46%), Gaps = 25/238 (10%)
Query: 102 DEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSA------QKLL 155
+EM K+ E+ +K I + EE+ E I EQ R Q A +K+
Sbjct: 336 EEMMWEKEEKIRELEEK--MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 393
Query: 156 SSEMDLR-CAEMKQNFENKNRELKEA---HEAELSELENNYKAALKAEKLAAQEK-LEEM 210
E +R EM Q E K E +E E E+ E E K + EK+ QEK + E
Sbjct: 394 EQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE--KMRRQEEKIREQEKKIREQ 451
Query: 211 GKEYKYLKNMFRTYQDSIYD------EMEEKWSKQKAKWKKDEKF--ERENILLQQKKKM 262
++ + + M + ++ + + E E K +Q+ K ++ E+ E+E + +Q++K+
Sbjct: 452 EEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKI 511
Query: 263 TKKFEMESGEEDKK-INESCSAVFENFIQEKEELLKQHQSDTLQLE-ELRKTKEVMQE 318
++ EM +E+K E E +QE+EE +++ + + E LR+ +E MQE
Sbjct: 512 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 49.3 bits (116), Expect = 7e-06
Identities = 46/233 (19%), Positives = 107/233 (45%), Gaps = 31/233 (13%)
Query: 53 QPTKPVVSPKMKIHSARQEETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRK-KRW 111
Q K K++ RQE+ K + + + + +R +E++ ++M +++ K W
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMW 421
Query: 112 ESEIPDKGRFSRTNIISDLEEQISELTA----IIEQMNRDHQSAQKLLSSEMDLRCAEMK 167
E E +++EQ ++ I EQ + + +K+ E EM
Sbjct: 422 EQE-------------EEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE------EMM 462
Query: 168 QNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQE-KLEEMGKEYKYLKNMFRTYQD 226
Q E K E E ++ E E K + EK+ QE K+ E K+ + + R ++
Sbjct: 463 QEQEEKMGE----QEGKMCEQEA--KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 516
Query: 227 SIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINE 279
+ ++ E+ W +++ +++EK + + ++++++ ++ E+ ++++K+ E
Sbjct: 517 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 67.8 bits (164), Expect = 2e-11
Identities = 56/275 (20%), Positives = 132/275 (48%), Gaps = 18/275 (6%)
Query: 130 LEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELE 189
+E + SE+ ++++ R + A KLL + L+ E ++ K + E +EL
Sbjct: 233 VESEKSEIQLNVKELKRKLERA-KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELW 291
Query: 190 NNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKF 249
N + + +EK++E ++ + + R ++ I ++ E+ +++ W+K+EK
Sbjct: 292 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 351
Query: 250 ERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEEL 309
R+ ++ +K++ ++ E E+++K+ E + EKEE +++ + + E++
Sbjct: 352 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ-----EEMMWEKEEKIRELEEKMHEQEKI 406
Query: 310 RKTKEVMQEE--LHAQALILESLNTNLYYTQLELQKEKAIVGNLEKML---------QTK 358
R+ +E QEE + Q E ++ + ++++++ + EK + Q K
Sbjct: 407 REQEEKRQEEEKIREQEKRQEQ-EAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK 465
Query: 359 FAETEEKYKHTIQILTEENIHLKQKIISKNEEICE 393
E E++ + EE IH +++I + E++ E
Sbjct: 466 IREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHE 500
Score = 64.7 bits (156), Expect = 2e-10
Identities = 77/355 (21%), Positives = 162/355 (45%), Gaps = 44/355 (12%)
Query: 53 QPTKPVVSPKMKIHSARQEETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWE 112
Q K K++ RQE+ K + + + + +R +E+ +++ +++K E
Sbjct: 409 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 468
Query: 113 SEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDL-RCAEMKQNFE 171
E + + EE+I E I Q + H+ +K+ E + R E + E
Sbjct: 469 EE-----KRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQE 523
Query: 172 NKNRELKEA---HEAELSELENNYKAALKA---EKLAAQEKLEEMGKEYKYLKNMFRTYQ 225
K RE +E E ++ E E ++ K EK+ +EK +E + + R +
Sbjct: 524 EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQE 583
Query: 226 DSIY------DEMEEKWSKQKAK-WKKDEKF--------ERENILLQQKKKMTKKFEMES 270
+ ++ E EEK +Q+ K WK++EK E+E + +Q++K+ ++ EM
Sbjct: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643
Query: 271 GEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESL 330
+E+K + E +++E++ +Q ++ Q E++R+ ++ ++E+ + I E
Sbjct: 644 EQEEKMGEQE-----EKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQ---EEKIREQ- 694
Query: 331 NTNLYYTQLELQKEKAIVGNLEKML--QTKFAETEEKYKHTIQILTEENIHLKQK 383
++ ++E+ + EKM + K E EEK + + + E+ + L+Q+
Sbjct: 695 ------EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 743
Score = 55.1 bits (131), Expect = 1e-07
Identities = 71/311 (22%), Positives = 139/311 (44%), Gaps = 47/311 (15%)
Query: 100 LGDEMFDRKKRWESEIPDKGRFSRTNIISD-----LEEQISELTAII-EQMNRDHQSAQK 153
LG E+ + ++++ + ++R N + EE+I E I EQ + + +K
Sbjct: 270 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK 329
Query: 154 LLSSEMDLRCAE--MKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEK----- 206
+ E +R E M + E R+ + E E K EK+ QE+
Sbjct: 330 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK 389
Query: 207 ------LEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAK-WKKDEKF-ERENILLQQ 258
LEE E + ++ Q+ +EK +Q+AK W+++EK E+E + +Q
Sbjct: 390 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 449
Query: 259 KKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEV--M 316
+KKM + + E E +KI E E QE+EE+ +Q E++ + +E+
Sbjct: 450 EKKMWR--QEEKIHEQEKIRE------EEKRQEQEEMWRQE-------EKIHEQEEIWRQ 494
Query: 317 QEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKML---QTKFAETEEKYKHTIQIL 373
+E++H Q + ++ + ++++++ + E+ + + K E EE ++
Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE----- 549
Query: 374 TEENIHLKQKI 384
EE +H ++KI
Sbjct: 550 -EEKMHEQEKI 559
Score = 54.3 bits (129), Expect = 2e-07
Identities = 53/207 (25%), Positives = 100/207 (48%), Gaps = 26/207 (12%)
Query: 131 EEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELEN 190
EE++ E I E+ R Q K+ E +R E ++ + +++E E + E
Sbjct: 550 EEKMHEQEKIWEEEKRQEQE-DKMWRQEEKIR--EQEEKVWRQEEKIREQEEKRQEQEEK 606
Query: 191 NYKAALKAEKLAAQE-KLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAK------- 242
+K + EK+ QE K++E ++ + + R Q+ + E EEK +Q+ K
Sbjct: 607 MWK---QEEKIREQEEKIQEQEEKIREQEEKIRE-QEEMTQEQEEKMGEQEEKMCEQEEK 662
Query: 243 --------WKKDEKF-ERENILLQQKKKMTKKFEMESGEEDKK-INESCSAVFENFIQEK 292
W+++EK E+E + +Q++K+ ++ EM +E+K E E +QE+
Sbjct: 663 MQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 722
Query: 293 EELLKQHQSDTLQLE-ELRKTKEVMQE 318
EE +++ + + E LR+ +E MQE
Sbjct: 723 EEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 49.7 bits (117), Expect = 5e-06
Identities = 50/206 (24%), Positives = 99/206 (48%), Gaps = 14/206 (6%)
Query: 102 DEMFDRKKRWESEIPDKGR---FSRTNIISDLEEQI-SELTAIIEQMNRDHQSAQKLLSS 157
++M +++K WE E + + + I + EE++ + I EQ + + +K+
Sbjct: 551 EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610
Query: 158 EMDLRCAEMK-QNFENKNRELKEA-HEAELSELENNYKAALKAEKLAAQEKLEEMGKEYK 215
E +R E K Q E K RE +E E E E K + EK+ QE+ + +E
Sbjct: 611 EEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETM 670
Query: 216 YLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEK--FERENILLQQKKKMTKKFEMESGEE 273
+ + Q+ E EEK +Q+ ++ E+ +E+E + +Q++KM ++ E +E
Sbjct: 671 WRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730
Query: 274 DKKINESCSAVFENFIQEKEELLKQH 299
+K + E ++++EE +++H
Sbjct: 731 EKMWEQ------EVRLRQQEEKMQEH 750
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 65.5 bits (158), Expect = 9e-11
Identities = 80/325 (24%), Positives = 153/325 (47%), Gaps = 44/325 (13%)
Query: 122 SRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAH 181
S+ ++ + E+QI +L I+ +QKL + +MDL + ++ E+ + +
Sbjct: 579 SKVELLREKEDQIKKLQEYID--------SQKLENIKMDLSYS--LESIEDPKQMKQTLF 628
Query: 182 EAELSELENNYKAA-LKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQK 240
+AE L+ ++A L++E L +EK++E+ YK ++N + YQ + + + + +K
Sbjct: 629 DAETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEK 688
Query: 241 AKWKKDEKFERENILLQQK--KKMTKKFEMESGEED--KKINESCSAVFEN-FIQEKEEL 295
+ + L+ K K + E+E D K++N+ V EN ++E+ L
Sbjct: 689 ELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKE---VEENEALREEVIL 745
Query: 296 LKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKML 355
L + +S ++E LRK + EELH I+ S L+ + KE + G LE++
Sbjct: 746 LSELKSLPSEVERLRKEIQDKSEELH----IITSEKDKLF--SEVVHKESRVQGLLEEIG 799
Query: 356 QTK--FAETEEKYKHTIQ-----------------ILTEENIHLKQKIISKNEEICEGCS 396
+TK A T+ YK T Q ++ EEN + Q+I++ ++E + S
Sbjct: 800 KTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDS 859
Query: 397 GRLASITVSKDDSDTVQDGSKKGQE 421
A T + +Q+ +++ QE
Sbjct: 860 SLGALKTELSYKTQELQEKTREVQE 884
Score = 50.8 bits (120), Expect = 2e-06
Identities = 67/344 (19%), Positives = 158/344 (45%), Gaps = 41/344 (11%)
Query: 71 EETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIPDKGRF--SRTNIIS 128
EE + E++N+S + ++ +LG + + + E+ +K R R N +
Sbjct: 838 EENERMNQEIVNLS------KEAQKFDSSLGALKTELSYKTQ-ELQEKTREVQERLNEME 890
Query: 129 DLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKN--RELKEAHEAELS 186
L+EQ+ + ++ + R+ + L++ ++ E+K + K+ ++L+E+ + E
Sbjct: 891 QLKEQLENRDSTLQTVERE----KTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERD 946
Query: 187 ELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKD 246
+L+++ + + QE+L + K + T + I +E+ ++ +
Sbjct: 947 QLKSDIHDTVNMN-IDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETK 1005
Query: 247 EKFERENILLQQKKKMTKKFE--MESGEEDKKINESCSAVF-------------ENFIQE 291
++F+++ + + +K+ + K + + +D +I E +F E+ I E
Sbjct: 1006 DEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAE 1065
Query: 292 KEEL---LKQHQSDTLQ-LEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAI 347
KE+L LK++ T++ EELR ++ +EL Q I+ + + EL +
Sbjct: 1066 KEQLKTDLKENIEMTIENQEELR----LLGDELKKQQEIVAQEKNHAIKKEGELSRTCDR 1121
Query: 348 VGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEI 391
+ +E+ L+ K + +EK + + + +E + QK I++ E +
Sbjct: 1122 LAEVEEKLKEKSQQLQEKQQQLLNV--QEEMSEMQKKINEIENL 1163
Score = 50.1 bits (118), Expect = 4e-06
Identities = 62/277 (22%), Positives = 128/277 (46%), Gaps = 23/277 (8%)
Query: 127 ISDLEEQISELTAIIEQMNRDHQSA-QKLLSSEMDLRCAEMKQNFENKN--RELKEAHEA 183
+S+ E +IS + +E +N Q+ Q++ E ++ + E N ++ KE +A
Sbjct: 1500 LSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKA 1559
Query: 184 ELSELENNYKAALKAEKLA--AQEKLEEMGKEYKYLKNMFRTYQ---DSIYDEMEEKWSK 238
+ S L++ L+ +QE+++ M KE + +K + Q D + + +E +K
Sbjct: 1560 KDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAK 1619
Query: 239 QKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKIN-ESCSAVFENFIQEKEELLK 297
K +K+ +F + + + ++KM + ++ E +K+N E+ Q E L+
Sbjct: 1620 MKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLE 1679
Query: 298 QHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYT---QLELQKEKAIVGNLEKM 354
+ +S T + ++LR +E ++ E + L NL T LE Q+E IV M
Sbjct: 1680 EMRSVTKERDDLRSVEETLKVE-------RDQLKENLRETITRDLEKQEELKIV----HM 1728
Query: 355 LQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEI 391
+ ET +K + + T E ++++ + N+ +
Sbjct: 1729 HLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDAL 1765
Score = 48.1 bits (113), Expect = 1e-05
Identities = 67/298 (22%), Positives = 133/298 (44%), Gaps = 38/298 (12%)
Query: 130 LEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELE 189
L+E E+ ++ ++ + D Q Q++L SE D ++K+N +E+ H EL+
Sbjct: 1430 LQESHDEMKSVAKEKD-DLQRLQEVLQSESD----QLKENI----KEIVAKHLETEEELK 1480
Query: 190 NNYKAALKAEKLAAQE---KLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKD 246
+ LK ++ E L E E ++ D + ++++E + +K+
Sbjct: 1481 VAH-CCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIY-------EKE 1532
Query: 247 EKFERENIL-LQQKKKMTKKFEMESGEEDKKINESCSAVFE--NFIQEKEELLKQHQSDT 303
E+F + I +Q+K K+F+ +D + S + E N +QE +E + Q
Sbjct: 1533 EQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEI---QIMI 1589
Query: 304 LQLEELRKTKEVMQ---EELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTK-F 359
+ EE+++ +E +Q ++L + + + + K A+ EKM + +
Sbjct: 1590 KEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHL 1649
Query: 360 AETEEKYKHTIQILTEENIHLKQKIISKNEEICEGCSGRLASITVSKDDSDTVQDGSK 417
E E K ++ + ENI L Q I+ +N E + S+T +DD +V++ K
Sbjct: 1650 KEQFETQKLNLENIETENIRLTQ-ILHENLE-------EMRSVTKERDDLRSVEETLK 1699
Score = 47.8 bits (112), Expect = 2e-05
Identities = 63/283 (22%), Positives = 123/283 (43%), Gaps = 43/283 (15%)
Query: 127 ISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELS 186
I+ L+ +ISE + ++ + + + + + + KQ+ E KN + A +
Sbjct: 980 INTLKSKISE--EVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNE 1037
Query: 187 ELENNYKA-ALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKK 245
+E K +L EK Q+ LE + E + LK + + + EE +
Sbjct: 1038 IIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEE------LRLLG 1091
Query: 246 DEKFERENILLQQKKKMTKKFEMESGEEDKKINESCS--AVFENFIQEKEELLKQHQSDT 303
DE +++ I+ Q+K KK + +++ +C A E ++EK + L++ Q
Sbjct: 1092 DELKKQQEIVAQEKNHAIKK--------EGELSRTCDRLAEVEEKLKEKSQQLQEKQQQL 1143
Query: 304 LQLEE-----LRKTKEV--MQEELHAQALILESLNT---------NLYYTQLE-LQKEKA 346
L ++E +K E+ ++ EL + L LE + T N Y +++ + KE+
Sbjct: 1144 LNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERK 1203
Query: 347 IVGNLEKMLQTK-------FAETEEKYKHTIQILTEENIHLKQ 382
++ L+K +T+ E E T + L +IHLK+
Sbjct: 1204 VLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKE 1246
Score = 45.1 bits (105), Expect = 1e-04
Identities = 72/303 (23%), Positives = 130/303 (42%), Gaps = 41/303 (13%)
Query: 123 RTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHE 182
R I DLE+Q E I+ ++HQ L + +E N ++L+ +++
Sbjct: 1710 RETITRDLEKQ--EELKIVHMHLKEHQETIDKLRGIV----SEKTNEISNMQKDLEHSND 1763
Query: 183 AELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAK 242
A LKA+ L Q EE+ + +LK T D + + EK K +
Sbjct: 1764 A------------LKAQDLKIQ---EELRIAHMHLKEQQETI-DKLRGIVSEKTDK-LSN 1806
Query: 243 WKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSD 302
+KD E N LQ+K + K E + K +NE+ + + E E+L KQ +
Sbjct: 1807 MQKD--LENSNAKLQEKIQELKANEHQLITLKKDVNET-----QKKVSEMEQLKKQIKDQ 1859
Query: 303 TLQLEELRKTKEVMQEELH-----AQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQT 357
+L L +L + ++LH ++++ E N L+L++++ E + +T
Sbjct: 1860 SLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQL----KESLQET 1915
Query: 358 KFAETE-EKYKHTIQILTEENIHLKQKIISKNEEICEGCSGRLASITVSKDD-SDTVQDG 415
K + E ++ T ++L++E+ K+ K E S + SKD+ +Q+
Sbjct: 1916 KARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQEL 1975
Query: 416 SKK 418
KK
Sbjct: 1976 QKK 1978
Score = 43.1 bits (100), Expect = 5e-04
Identities = 65/324 (20%), Positives = 131/324 (40%), Gaps = 37/324 (11%)
Query: 125 NIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRE-LKEAHEA 183
+ I ++E+Q EL I+ + +D + +LR ++ QN + E LK+ E+
Sbjct: 2197 DFIDEVEKQ-KELLIKIQHLQQDCDVPSR------ELRDLKLNQNMDLHIEEILKDFSES 2249
Query: 184 ELSELENNYKAALKAEKLAAQEKLEEMGKEY--KYLKNMFRTYQDSIYD----------- 230
E ++ ++ L K Q E + + + LKN + D I
Sbjct: 2250 EFPSIKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIA 2309
Query: 231 ------EMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCS-- 282
E EE+ + +W++D K +E K T K + SG + +
Sbjct: 2310 IMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNP 2369
Query: 283 AVFENFIQEKEELLKQHQSDTLQLEELRKTKE----VMQEELHAQALILESLNTNLYYTQ 338
V Q E +++ ++ + +E KE MQ+EL I+ L ++ +
Sbjct: 2370 HVTSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESN 2429
Query: 339 LELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEICEGCSGR 398
L+K K + ++LQ K A + YK I+ L + + + + + +E + S
Sbjct: 2430 KCLEKTKETI----QVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKMKNAKEFEKEISAT 2485
Query: 399 LASITVSKDDSDTVQDGSKKGQES 422
A++ K+ +++ ++ Q++
Sbjct: 2486 KATVEYQKEVIRLLRENLRRSQQA 2509
Score = 42.7 bits (99), Expect = 6e-04
Identities = 54/279 (19%), Positives = 124/279 (44%), Gaps = 27/279 (9%)
Query: 127 ISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELS 186
+++ ++++SE+ + +Q+ + KL ++L ++ +N E +KE
Sbjct: 1839 VNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNL-AQKLHENLEEMKSVMKERDNLRRV 1897
Query: 187 ELENNYKAALKAEKLAAQEKLEE-------MGKEYKYLKNMFRTYQDSIYDEMEEKWSKQ 239
E LK E+ +E L+E + +E K + + + +++++ D++ EK S++
Sbjct: 1898 E------ETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETV-DKLREKISEK 1950
Query: 240 KAKWKKDEK-FERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQ 298
+ +K ++ LQ+K + +K E++ + +N S I E E+L KQ
Sbjct: 1951 TIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMS-----HKKINEMEQLKKQ 2005
Query: 299 HQSDTLQLEELRKTKEVMQEELH---AQALILESLNTNLYYTQLELQKEK-AIVGNLEKM 354
++ L ++ +R + ++LH + I+ L + L+ E+ + L +M
Sbjct: 2006 FEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREM 2065
Query: 355 LQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEICE 393
+ + K ++L++ HL + + K I E
Sbjct: 2066 IARD--RQNHQVKPEKRLLSDGQQHLTESLREKCSRIKE 2102
Score = 30.0 bits (66), Expect = 4.1
Identities = 69/297 (23%), Positives = 112/297 (37%), Gaps = 28/297 (9%)
Query: 127 ISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELS 186
I DL++Q+ E++ + +LL E DL + EN R L + L
Sbjct: 352 IMDLKKQLEEVSLETRAQAMEKDQLAQLLE-EKDLLQKVQNEKIENLTRMLVTSSSLTLQ 410
Query: 187 ELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKK- 245
+ KA K K+ +M KN Q +I + K K +
Sbjct: 411 Q---ELKAKRKRRVTWCLGKINKM-------KNSNYADQFNIPTNITTKTHKLSINLLRE 460
Query: 246 -DEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTL 304
DE E+ + + E+E K +N+ EN E L + + L
Sbjct: 461 IDESVCSESDVFSNT--LDTLSEIEWNPATKLLNQ------ENIESELNSLRADYDNLVL 512
Query: 305 QLEELRKTKEVMQEELHAQALI--LESLNTNLYYTQ-LELQKEKAIVGNLEKMLQTKFAE 361
E+LR KE M+ +L + + E+L Q ++L E + + NL K + +
Sbjct: 513 DYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQD 572
Query: 362 TEEKYKHTIQILTEENIHLK--QKII--SKNEEICEGCSGRLASITVSKDDSDTVQD 414
E + +++L E+ +K Q+ I K E I S L SI K T+ D
Sbjct: 573 LENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFD 629
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 64.7 bits (156), Expect = 2e-10
Identities = 80/336 (23%), Positives = 157/336 (46%), Gaps = 52/336 (15%)
Query: 93 REQISVTLGDEMFDRKKRWESEIPDKGRFSRTNI-ISDLEEQISELTAIIEQMNRDHQSA 151
+ Q+ V + + + ++K+ +S +K + + ++ ++EQ+ + ++Q ++ Q
Sbjct: 898 KHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQL 957
Query: 152 QKLLSSEMDLRCAEMKQNFENKNRELKEAHEAEL-------SELENNYKAALK--AEKLA 202
Q ++ E+KQ+ E K +++ EA + EL +ELEN + L A++LA
Sbjct: 958 QGNIN--------ELKQSSEQKKKQI-EALQGELKIAVLQKTELENKLQQQLTQAAQELA 1008
Query: 203 AQ-EKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFE----------- 250
A+ EK+ + Y+ + F+ Q Y E + ++ +EK
Sbjct: 1009 AEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRN 1068
Query: 251 ---RENILLQQKKKMTKKFEMESGEEDKKINESCSAV----FENFIQEKEELLKQHQSDT 303
+N L+Q+ K E +S ++++++ E C A+ E ++EKE L +S
Sbjct: 1069 QIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKE--LVNEKSKL 1126
Query: 304 LQLEEL--RKTKEV--MQEELHAQALILESLNTNLY-YTQLELQKEKAIVGNLEKMLQTK 358
++EE+ R+ KE+ + EEL + L TNL QL +Q++ + G + + K
Sbjct: 1127 AEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSL---K 1183
Query: 359 FAETEEKYKHTI---QILTEENIHLKQKIISKNEEI 391
A +EK I Q+ EE LK++ I K ++
Sbjct: 1184 AAVEQEKRNQQILKDQVKKEEE-ELKKEFIEKEAKL 1218
Score = 55.8 bits (133), Expect = 7e-08
Identities = 72/275 (26%), Positives = 126/275 (45%), Gaps = 39/275 (14%)
Query: 130 LEEQISELTAIIEQMNRDHQSAQKLLSSEMD-----LRCAE-----MKQNFENKNRELKE 179
L+EQ+++LT ++ + H+ AQ+ L ++ LR A+ ++ + N +L E
Sbjct: 573 LQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNE 632
Query: 180 AHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQ 239
+ E ++S+L+ KA K E L + E + + L+N T Q+++ D KQ
Sbjct: 633 SKE-KVSQLDIQIKA--KTELLLSAEAAKT--AQRADLQNHLDTAQNALQD-------KQ 680
Query: 240 KAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQH 299
+ K + ++ LQ K++ + E E +K E +E E +K+
Sbjct: 681 QELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKY-----LSLEQKTEELEGQIKKL 735
Query: 300 QSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQK----EKAIVGNLEKML 355
++D+L E++ +KE ++L Q LNT+L EL K EK IV + L
Sbjct: 736 EADSL---EVKASKEQALQDLQQQ----RQLNTDLELRATELSKQLEMEKEIVSSTRLDL 788
Query: 356 QTKFAETEEKYKHTIQILTEENIHLKQKIISKNEE 390
Q K +E E K + EE LKQ + ++E
Sbjct: 789 QKK-SEALESIKQKLTKQEEEKQILKQDFETLSQE 822
Score = 54.7 bits (130), Expect = 2e-07
Identities = 71/313 (22%), Positives = 140/313 (44%), Gaps = 34/313 (10%)
Query: 127 ISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAEL- 185
I LE E+ A EQ +D Q Q+ L+++++LR E+ + E + +E+ + +L
Sbjct: 732 IKKLEADSLEVKASKEQALQDLQQ-QRQLNTDLELRATELSKQLEME-KEIVSSTRLDLQ 789
Query: 186 --SELENNYKAAL---KAEKLAAQEKLEEMGKEYKY----LKNMFRTYQDSIYDEMEEKW 236
SE + K L + EK ++ E + +E K L N +T +
Sbjct: 790 KKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTEL-------- 841
Query: 237 SKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAV--FENFIQEKEE 294
QK K +K+ + + + K++ + E +K+ + +A+ E +E +
Sbjct: 842 --QKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKH 899
Query: 295 LLKQHQSDTL-QLEELRKTKEVMQEELHAQALILESLNTNLYYTQLEL----QKEKAIVG 349
L+ +TL + +EL+K+ E +E H L L S+ L Q L ++E+ + G
Sbjct: 900 QLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQG 959
Query: 350 NLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEICEGCSGRLASITVSKDDS 409
N+ ++ Q+ +E+K K + E I + QK +N ++ + + + K+
Sbjct: 960 NINELKQS----SEQKKKQIEALQGELKIAVLQKTELEN-KLQQQLTQAAQELAAEKEKI 1014
Query: 410 DTVQDGSKKGQES 422
+Q+ +K QE+
Sbjct: 1015 SVLQNNYEKSQET 1027
Score = 42.0 bits (97), Expect = 0.001
Identities = 56/234 (23%), Positives = 109/234 (46%), Gaps = 21/234 (8%)
Query: 129 DLEEQISELTAIIEQM--NRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELS 186
DL+ +L+ E + NR+ Q L E+ A ++Q+ K ++L+E +A L
Sbjct: 1048 DLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKA-LQ 1106
Query: 187 ELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKD 246
+++ K+ + E + + KL E+ + + Q+ ++ E+ K + K+
Sbjct: 1107 DIQKE-KSLKEKELVNEKSKLAEIEE--------IKCRQEKEITKLNEELKSHKLESIKE 1157
Query: 247 --EKFERENILLQQKKKMTKKFE-MESGEEDKKINESCSAVFENFIQEKEELLKQHQSDT 303
+ + +L+QQK ++ K + +++ E +K N+ + + +E+EEL K+
Sbjct: 1158 ITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQI--LKDQVKKEEEELKKEFIEKE 1215
Query: 304 LQLEELRKTKEV---MQEELHAQALI-LESLNTNLYYTQLELQKEKAIVGNLEK 353
+L K KEV EE A+ + + +LN NL + E Q + V LEK
Sbjct: 1216 AKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEK 1269
Score = 40.4 bits (93), Expect = 0.003
Identities = 60/306 (19%), Positives = 123/306 (40%), Gaps = 42/306 (13%)
Query: 107 RKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEM--DLRCA 164
++++W SE K L++Q ++ ++ + + QS ++ L +
Sbjct: 100 KEEKWYSEELKK----ELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIK 155
Query: 165 EMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTY 224
+MK FE K +L E++++++ Y ++ + AA++K+ + +E L
Sbjct: 156 QMKDLFEQKAAQLA----TEIADIKSKYDEE-RSLREAAEQKVTRLTEE---LNKEATVI 207
Query: 225 QDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAV 284
QD + ++ + A KK+ L Q + + +E E +K+ + C +
Sbjct: 208 QDLKTELLQRPGIEDVAVLKKE---------LVQVQTLMDNMTLERERESEKLKDECKKL 258
Query: 285 FENFI-------QEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILES-LNTNLYY 336
+ Q + EL K Q + ++EL+K K + E + E+ L Y
Sbjct: 259 QSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDY 318
Query: 337 TQLELQKEKAIVG--NLEKMLQTKFAETE---------EKYKHTIQILTEENIHLKQKII 385
T+LE + + V N++ L K + + E H I + E QK+
Sbjct: 319 TKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLK 378
Query: 386 SKNEEI 391
+ E+
Sbjct: 379 EELSEV 384
Score = 33.9 bits (76), Expect = 0.29
Identities = 36/168 (21%), Positives = 75/168 (44%), Gaps = 23/168 (13%)
Query: 129 DLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENK----NRELKE----- 179
+L+ + L A +EQ R+ Q++L ++ E+K+ F K + E+KE
Sbjct: 1174 ELQGKADSLKAAVEQEKRN----QQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGM 1229
Query: 180 -AHEAELSELE------NNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEM 232
HE ++L N +K E ++Q ++ E+ K+ L+ + ++ +
Sbjct: 1230 KKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQ 1289
Query: 233 EEKWSKQKAKWKKD---EKFERENILLQQKKKMTKKFEMESGEEDKKI 277
+E+ + + K + EK + + + LQ+K T E G E++ +
Sbjct: 1290 DERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAAVQELGRENQSL 1337
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 63.9 bits (154), Expect = 3e-10
Identities = 72/310 (23%), Positives = 136/310 (43%), Gaps = 52/310 (16%)
Query: 127 ISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKE---AHEA 183
++ LEE +SE IIE++ + + E+ ++F +N++LKE A +A
Sbjct: 583 LATLEEALSEKERIIERLKEQRERDDRERLEEI--------ESFRKENKDLKEKVNALQA 634
Query: 184 ELSELENNY-----------------KAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQD 226
EL+E E++ + LK+ ++A ++K EE K LK D
Sbjct: 635 ELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDD 694
Query: 227 SIYDEMEEKWSKQKAKWKKDEKFERENILLQQKK-----KMTKKFEMESGEEDKKINESC 281
S M +++ Q + K+ + R+ Q + ++ K+ E E ++DKKI E
Sbjct: 695 S---RMNPEFADQIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELE 751
Query: 282 SAVFENFIQEKEELLKQHQSDTLQ-------LEELRKTKEVMQEELHAQALILESLNTNL 334
S + + +++ + L+ LEE+R+ ++ M + ++Q L +E L L
Sbjct: 752 SLTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMAD--NSQHLQIEELMNAL 809
Query: 335 YYTQLELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEICEG 394
T+ EL KA + + ++ L EK H + E L++ + K E +
Sbjct: 810 EKTRQELDATKARLASTQQSL-------AEKEAHLANLRIERRKQLEEILEMKQEALLAA 862
Query: 395 CSGRLASITV 404
S + A+I +
Sbjct: 863 ISEKDANIAL 872
Score = 47.4 bits (111), Expect = 2e-05
Identities = 69/294 (23%), Positives = 125/294 (42%), Gaps = 29/294 (9%)
Query: 131 EEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELEN 190
E +I+ L IE + + K L++ D R ++ + N + L EA LSE E
Sbjct: 538 ERKINVLQKKIENLQEQLRDKDKQLTNLKD-RVKSLQTDSSNTDTALATLEEA-LSEKER 595
Query: 191 NYKAALKAEKLAAQEKLEEMG---KEYKYLKNMFRTYQ-------DSIYDEMEEKWSKQK 240
+ + + +E+LEE+ KE K LK Q S+ D E S
Sbjct: 596 IIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLAS 655
Query: 241 AKWKKDEKFERENILLQQKKKMTKKFEME-----SGEEDKKINESCSAVFENFIQE---- 291
A K+D K + I ++QKK+ K E + + E+D ++N + + +E
Sbjct: 656 AGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKEASYY 715
Query: 292 KEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNL 351
++E K Q++ +L E+ K E + + + LESL Q K+ A + +
Sbjct: 716 RDECGKA-QAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQ---NKKVANLKHN 771
Query: 352 EKMLQTKFAETEEKYKHTIQILTEENIHLK----QKIISKNEEICEGCSGRLAS 401
+++ + K A+ E+ + + + + HL+ + K + + RLAS
Sbjct: 772 QQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLAS 825
Score = 46.6 bits (109), Expect = 4e-05
Identities = 74/317 (23%), Positives = 134/317 (42%), Gaps = 52/317 (16%)
Query: 123 RTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHE 182
RT +++ E Q+S L I++Q +++ ++ L L+ K E+K+
Sbjct: 328 RTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKI 387
Query: 183 AELS----ELENNYKAALKAEKLAAQEKLEEMGKE---YKYLKNMFRTYQDSIYDEMEEK 235
A L +LE+ + LKA + E EE K+ YK +T D + E+ +K
Sbjct: 388 ASLERNIRDLEDEIQM-LKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKK 446
Query: 236 WSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEEL 295
S+ A K E +N +Q ++ K+ + + E+ I ++ ++EKE
Sbjct: 447 ESELLALQTKLETLSNQNSDCKQHIEVLKE-SLTAKEQRAAILQTEVDALRLRLEEKESF 505
Query: 296 L----KQHQS----------------DTLQLEE-----LRKTKEVMQEELH--------- 321
L KQ Q D L+++E L+K E +QE+L
Sbjct: 506 LNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNL 565
Query: 322 ---AQALILESLNTNLYYTQLE--LQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEE 376
++L +S NT+ LE L +++ I+ L++ + E E+ I+ +E
Sbjct: 566 KDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEE----IESFRKE 621
Query: 377 NIHLKQKIISKNEEICE 393
N LK+K+ + E+ E
Sbjct: 622 NKDLKEKVNALQAELTE 638
Score = 30.4 bits (67), Expect = 3.2
Identities = 26/103 (25%), Positives = 54/103 (52%), Gaps = 14/103 (13%)
Query: 295 LLKQHQSDTL-----QLEELRKTKEVMQEELHAQALIL-ESLNTNLYYTQLELQKEKAIV 348
+L+Q + T+ QL+EL++ +++++EL + L S+N+ + EL+KE+
Sbjct: 138 MLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKER--- 194
Query: 349 GNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEI 391
+L+ + A K +++ EEN HL+ I + +E+
Sbjct: 195 -----VLRKEEAARMSVLKEQMRVSHEENQHLQLTIQALQDEL 232
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 61.2 bits (147), Expect = 2e-09
Identities = 84/366 (22%), Positives = 156/366 (42%), Gaps = 49/366 (13%)
Query: 69 RQEETNKSFYE--------VINVSPG------YQLVRNREQISVTLGD---------EMF 105
RQ ET K+ E ++N S G +Q+ R Q++ GD ++
Sbjct: 275 RQTETEKNQLEQELELSRRLLNQSEGSRETLLHQVEELRTQLTKAEGDRKGLQHQVSQIS 334
Query: 106 DRKKRWESEIPDKGRFSR--TNIISDLEEQISELTAIIEQMNRDHQSAQ----KLLSSEM 159
++ ++ E + RF R DLE+Q+S+L Q+N +++ K
Sbjct: 335 KQQSNYQDEQGEDWRFRRGVEREKQDLEKQMSDLRV---QLNFSAMASELEEVKRCMERK 391
Query: 160 DLRCAEMKQNFENKNRELKEAHEAELSELEN-----NYKAALKAEKLAAQEKLEEMGKEY 214
D A + EN REL+ + +L L+ N+ +AE+ A ++ E+ +
Sbjct: 392 DKEKAHLASQVENLTRELENGEKQQLQMLDRLKEIQNHFDTCEAERKHADLQISELTRHA 451
Query: 215 KYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEED 274
+ Y + + E ++ K ++D K + + + Q K K KK E ++
Sbjct: 452 EDATKQAERYLSEL--QQSEALKEEAEKRREDLKLKAQESIRQWKLKH-KKLERALEKQS 508
Query: 275 KKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRK------TKEVMQE-ELHAQALIL 327
+ ++E + ++EK+EL Q + Q+E LRK TK +QE ELH++ L
Sbjct: 509 ETVDE-LTGKNNQILKEKDELKTQLYAALQQIENLRKELNDVLTKRALQEEELHSKEEKL 567
Query: 328 ESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISK 387
+ ++ +LE++ + LE L+ K ++ + + K L EE LK+
Sbjct: 568 RDIKSHQADLELEVKNSLDTIHRLESELK-KQSKIQSQMKVEKAHLEEEIAELKKSQAQD 626
Query: 388 NEEICE 393
++ E
Sbjct: 627 KAKLLE 632
Score = 38.9 bits (89), Expect = 0.009
Identities = 63/257 (24%), Positives = 111/257 (43%), Gaps = 47/257 (18%)
Query: 128 SDLEEQISELTA-IIEQMN--RDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAE 184
S+ E I L A +E+ N + H+ + L S+ D E+ QN EN+N++LK ++
Sbjct: 727 SEAENHIRTLKAESLEEKNMAKIHRGQLEKLKSQCDRLTEELTQN-ENENKKLKLKYQCL 785
Query: 185 LSELENNYK-AALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIY-------------- 229
+LE K +++ E L ++EE + K T Q+SI
Sbjct: 786 KDQLEEREKHISIEEEHL---RRMEEARLQLKDQLLCLETEQESILGVIGKEIDAACKTF 842
Query: 230 --DEMEE---------------KW---SKQKAKWKKDEKFERENILLQQKKK-MTKKFEM 268
D +E+ +W SK K +W +E EREN + + M + ++
Sbjct: 843 SKDSVEKLKVFSSGPDIHYDPHRWLAESKTKLQWLCEELKERENREKNLRHQLMLCRQQL 902
Query: 269 ESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILE 328
+ E+K+ C +F+ I+ +E+LL + + L E + K+ L + + LE
Sbjct: 903 RNLTENKESELQC--LFQQ-IERQEQLLDEIHREKRDLLEETQRKDEEMGSLQDRVIALE 959
Query: 329 SLNTNLYYTQLELQKEK 345
+ +T + LE EK
Sbjct: 960 T-STQVALDHLESVPEK 975
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 60.8 bits (146), Expect = 2e-09
Identities = 72/310 (23%), Positives = 134/310 (43%), Gaps = 37/310 (11%)
Query: 117 DKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRE 176
+K R ++ EE++++ + Q R A ++ + D A+ + F K
Sbjct: 1585 EKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQD-DREMAQAEGKFAQKEET 1643
Query: 177 LKEAHEAELSELEN----NYKAALKAEKLAAQE-KLEEMGKEYKYLKNMFRT-------- 223
L + E E E K A K EK+A +E KL + G + +KN+
Sbjct: 1644 LAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQR 1703
Query: 224 ------YQDSIYDEMEE-KWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKK 276
+ + E+EE +W ++ WK++E + E L+++KKK+ ++ E + + +K
Sbjct: 1704 EQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKL 1763
Query: 277 INESCSAVFEN--FIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQAL-------IL 327
E E IQEKE+L + + + E L + +E + E+ A +
Sbjct: 1764 SEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSM 1823
Query: 328 ESLNTN---LYYTQLELQKEKAIVGNLEKMLQTK--FAETEEKYKHTIQILTE--ENIHL 380
E L N LY + Q++K + EK+ Q K +E+ H+ + L + + +
Sbjct: 1824 EELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGM 1883
Query: 381 KQKIISKNEE 390
KI+++ EE
Sbjct: 1884 FNKILAQVEE 1893
Score = 50.8 bits (120), Expect = 2e-06
Identities = 48/205 (23%), Positives = 93/205 (45%), Gaps = 43/205 (20%)
Query: 108 KKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMK 167
+KR E++ DK + ++ + ++E + E + + +S L + L E +
Sbjct: 2198 RKRKEAKRGDKPKEKFSSQVDEVESE--------EHFSEEMESLLDELEKQESLSSEEEE 2249
Query: 168 QNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDS 227
+ E + RE +E E E + K EE G+E +
Sbjct: 2250 EREEEEEREEEEVREEE------------------EERKEEEEGEEKQV----------- 2280
Query: 228 IYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFEN 287
E EE+ K+K K KK E+ + + + ++K+++ + E ES ++++ ESCS E
Sbjct: 2281 ---EKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCS--LEE 2335
Query: 288 FIQEKEELLKQHQSDTLQLEELRKT 312
+ ++E+LK+ + LQ E+ RK+
Sbjct: 2336 EVDREKEILKKEKQFKLQ-EQRRKS 2359
Score = 49.7 bits (117), Expect = 5e-06
Identities = 57/246 (23%), Positives = 115/246 (46%), Gaps = 36/246 (14%)
Query: 104 MFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRC 163
M +++++ E R I+ D EE E +I + R + ++ +
Sbjct: 2153 MINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGD----- 2207
Query: 164 AEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRT 223
+ K+ F ++ E+ E+ E E+E+ K E L+++E+ E +E +
Sbjct: 2208 -KPKEKFSSQVDEV-ESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEERE------- 2258
Query: 224 YQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSA 283
++ + +E EE+ +++ + K+ EK E E ++KKK KK E++ EE
Sbjct: 2259 -EEEVREEEEERKEEEEGEEKQVEKEEEEK---KKKKKEKKKEEVQEKEE---------- 2304
Query: 284 VFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQK 343
VFE EKEE++ + ++++L EE + ++EE+ + IL+ +L+ Q+
Sbjct: 2305 VFE----EKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEK----QFKLQEQR 2356
Query: 344 EKAIVG 349
K++ G
Sbjct: 2357 RKSLRG 2362
Score = 44.3 bits (103), Expect = 2e-04
Identities = 68/335 (20%), Positives = 142/335 (42%), Gaps = 37/335 (11%)
Query: 95 QISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDH----QS 150
++ T G +F + +R ++ K + +S +++++ ++++ RD Q
Sbjct: 2035 KLEFTRGQRIFVQGQRKLAKASRK-LIKKRESLSKEPAKLNKILKALQKLTRDERKLTQE 2093
Query: 151 AQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAEL-SELENNYKAALKAEKLAAQEKLEE 209
K+ + L E + + E ++KE +E SEL + K + ++ A +
Sbjct: 2094 EIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRM 2153
Query: 210 MGKEYKYLKN---MFRTYQDSIYDEMEE--------------KWSKQKAKWKKD---EKF 249
+ KE K + + R + + I D+ EE +W K+K + D EKF
Sbjct: 2154 INKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKF 2213
Query: 250 ERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEEL 309
+ ++ ++ ++ EMES ++ + ES S+ E +E+EE ++ + + + EE
Sbjct: 2214 SSQVDEVESEEHFSE--EMESLLDELEKQESLSSEEE---EEREEEEEREEEEVREEEEE 2268
Query: 310 RKT------KEVMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAETE 363
RK K+V +EE + E + + ++++ I+ E + E E
Sbjct: 2269 RKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEE 2328
Query: 364 EKYKHTIQILTEENIHLKQKIISKNEEICEGCSGR 398
E ++ E+ I K+K E+ + GR
Sbjct: 2329 ESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGR 2363
Score = 42.4 bits (98), Expect = 8e-04
Identities = 63/341 (18%), Positives = 147/341 (43%), Gaps = 41/341 (12%)
Query: 77 FYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIPDKGRFSR--TNIISDLEEQI 134
F E NV+ G ++ + E+ + + + + E ++ G+ R T D+ E++
Sbjct: 1375 FLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERKV---GKIKREMTKEERDMSEEV 1431
Query: 135 SELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELENNYKA 194
E+ + E++ + KL+ E + K+ ++ E K+ H E + +K
Sbjct: 1432 EEMATLEEKVVKQEG---KLVMIERTPSWQDWKKAWD----EWKQVH-GETRKSWKAWKE 1483
Query: 195 ALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENI 254
+ L +EKL + G++ + M + + ++E ++ W + K+++++ E
Sbjct: 1484 EWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDE-- 1541
Query: 255 LLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQH----QSDTLQLEELR 310
++ + ++ E E+++++ E + IQE+ + + H +++ + +E R
Sbjct: 1542 ---EEVTLEEEVSREGEEKEQQVTEE-----QRHIQEEHKWARIHRKRARAEKKRAQEER 1593
Query: 311 KTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAETEEKYKHTI 370
K + +E+L + L L +++ ++ + E KFA+ EE
Sbjct: 1594 KLAQ-EEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAE----GKFAQKEETLAQRG 1648
Query: 371 QILTEENIHLKQK---------IISKNEEICEGCSGRLASI 402
+ L++E L QK +++ EE G+LA +
Sbjct: 1649 EKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEV 1689
Score = 38.5 bits (88), Expect = 0.012
Identities = 45/201 (22%), Positives = 90/201 (44%), Gaps = 16/201 (7%)
Query: 126 IISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKE------ 179
+I + E+ + E+ R + ++L+ +M L A+ ++ + N EL +
Sbjct: 1777 LIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKL--AQKRERWINSMEELTKNKMILY 1834
Query: 180 -----AHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEE 234
A E + E A K L +E+L K+ +KN + + I ++EE
Sbjct: 1835 QKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMF-NKILAQVEE 1893
Query: 235 KWSKQKAKW-KKDEKF-ERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEK 292
K +++K KK EK E E L+Q + + KK E + E+ K E + ++ +
Sbjct: 1894 KLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGE 1953
Query: 293 EELLKQHQSDTLQLEELRKTK 313
++ K+ ++ L+++ L + K
Sbjct: 1954 LDIAKEEKALNLEMKRLAEEK 1974
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 60.5 bits (145), Expect = 3e-09
Identities = 57/276 (20%), Positives = 127/276 (46%), Gaps = 27/276 (9%)
Query: 130 LEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELE 189
+E + SE+ ++++ R + A KLL + L+ E ++ K + E +EL
Sbjct: 294 VESEKSEIQLNVKELKRKLERA-KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELW 352
Query: 190 NNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYD-------------EMEEKW 236
N + + +EK++E ++ + + R ++ I + E EEK
Sbjct: 353 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 412
Query: 237 SKQKAK-WKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEEL 295
+Q+ W+K+EK R+ ++ +K++ ++ E + E++K + E I+E+E+
Sbjct: 413 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 472
Query: 296 LKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKML 355
+Q Q E++R+ +E ++E+ ++ + ++ +++ I ++
Sbjct: 473 QEQEAKMWRQEEKIREQEEKIREQ-----------EEKMWRQEEKIHEQEKIREEEKRQE 521
Query: 356 QTKFAETEEKYKHTIQILTE-ENIHLKQKIISKNEE 390
Q + EEK + +I + E IH +++ I K EE
Sbjct: 522 QEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEE 557
Score = 60.5 bits (145), Expect = 3e-09
Identities = 69/281 (24%), Positives = 128/281 (45%), Gaps = 19/281 (6%)
Query: 53 QPTKPVVSPKMKIHSARQEETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWE 112
Q K K++ RQE+ K + + + + +R +E+ +++ +++K E
Sbjct: 456 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIRE 515
Query: 113 SEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDL-RCAEMKQNFE 171
E + + EE+I E I Q + H+ +K+ E + R E + E
Sbjct: 516 EE-----KRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQE 570
Query: 172 NKNRELKEA---HEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSI 228
K RE +E E ++ E E + + EK+ QE++ + +E + Q+
Sbjct: 571 EKIREQEEKVWRQEEKIREQEEKIRE--QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 628
Query: 229 YDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKK-INESCSAVFEN 287
E EEK +Q+ K ++ EK RE Q++K+ ++ EM +E+K E E
Sbjct: 629 MQEQEEKMRRQEEKIREQEKKIRE-----QEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 683
Query: 288 FIQEKEELLKQHQSDTLQLE-ELRKTKEVMQE-ELHAQALI 326
+QE+EE +++ + + E LR+ +E MQE + H +A I
Sbjct: 684 KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 724
Score = 59.7 bits (143), Expect = 5e-09
Identities = 71/303 (23%), Positives = 142/303 (46%), Gaps = 44/303 (14%)
Query: 102 DEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDL 161
+EM K+ E+ +K I + EE+ E I EQ R Q A K+ E +
Sbjct: 430 EEMMWEKEEKIRELEEK--MHEQEKIREQEEKRQEEEKIREQEKRQEQEA-KMWRQEEKI 486
Query: 162 RCAEMK--QNFENKNRELKEAHEAELSELENNYKAA----LKAEKLAAQEKL-------- 207
R E K + E R+ ++ HE E E + + EK+ QE++
Sbjct: 487 REQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIH 546
Query: 208 EEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKF-ERENILLQQKKK----- 261
E+ K K + M+R ++ ++D+ E+ +++ W+++EK E+E + +Q++K
Sbjct: 547 EQEEKIRKQEEKMWRQ-EEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQE 605
Query: 262 -MTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEEL 320
MT++ E + GE+++K+ E E +QE+EE +++ + ++ E K +E++
Sbjct: 606 EMTQEQEEKMGEQEEKMCEQ-----EEKMQEQEEKMRRQEE---KIREQEKKIREQEEKI 657
Query: 321 HAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHL 380
Q +++ ++ ++E+ + EKM E EEK + + + E+ + L
Sbjct: 658 REQEEMMQEQEEKMW------EQEEKMCEQEEKM-----QEQEEKMRRQEEKMWEQEVRL 706
Query: 381 KQK 383
+Q+
Sbjct: 707 RQQ 709
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 60.5 bits (145), Expect = 3e-09
Identities = 75/320 (23%), Positives = 155/320 (48%), Gaps = 41/320 (12%)
Query: 117 DKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRE 176
DK + ++ +LE++++++ + + ++ + Q+ +++E+++ E KQ+ ++K E
Sbjct: 255 DKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEK-QQCMATELEMTVKEAKQD-KSKEAE 312
Query: 177 LKEAHEAELSELENNYKAALKAEKLAAQEKL---EEMGKEYKYLKNMFRTYQDSIYDEME 233
K A +AE+ +L+N+ + A + E+LAAQ+ EE +L++ R Q +
Sbjct: 313 CK-ALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLL---- 367
Query: 234 EKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAV---FENFIQ 290
KQKA ++ +RE +LQ++ M +K + + + ++++ S EN +
Sbjct: 368 --LDKQKA--DTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSEALRKLENSDK 423
Query: 291 EKEELLK------QHQSDTL-----QLEELRKTKEVMQEELHAQALILESLNTNLYYTQL 339
EK +L K +D L Q E K ++E+L +LE L ++
Sbjct: 424 EKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLKKSK- 482
Query: 340 ELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEICEGCSGRL 399
+ EK + G LE + Q +F + ++ K + L EEN +L+ ++ + CS +L
Sbjct: 483 --EHEKLMEGELEALRQ-EFKKKDKTLKENSRKLEEENENLRAEL--------QCCSTQL 531
Query: 400 -ASITVSKDDSDTVQDGSKK 418
+S+ +QD +K+
Sbjct: 532 ESSLNKYNTSQQVIQDLNKE 551
Score = 48.1 bits (113), Expect = 1e-05
Identities = 65/309 (21%), Positives = 135/309 (43%), Gaps = 46/309 (14%)
Query: 102 DEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSA---QKLLSSE 158
++M DR K E + +I LEE + E T ++E + + +KL+ E
Sbjct: 440 NDMLDRIKHQHRE--------QGSIKCKLEEDLQEATKLLEDKREQLKKSKEHEKLMEGE 491
Query: 159 MDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLK 218
++ ++Q F+ K++ LKE E EN L+AE +LE +Y +
Sbjct: 492 LEA----LRQEFKKKDKTLKENSRKLEEENEN-----LRAELQCCSTQLESSLNKYNTSQ 542
Query: 219 NMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKIN 278
+ + I + E S Q + D+ ++E LQ +TK E+ + + +
Sbjct: 543 QVIQDLNKEIALQKESLMSLQA---QLDKALQKEKHYLQTT--ITK----EAYDALSRKS 593
Query: 279 ESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNL---- 334
+C +++ + + +S L + ++ K ++EE+ A ++ LNT L
Sbjct: 594 AACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLR 653
Query: 335 -YYTQLELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILT----------EENIHLKQK 383
++ + EL+ A LE+M + + ++++++ +++L EE LK+
Sbjct: 654 GFHQESELEVH-AFDKKLEEM-SCQVLQWQKQHQNDLKMLAAKEEQLREFQEEMAALKEN 711
Query: 384 IISKNEEIC 392
++ ++E C
Sbjct: 712 LLEDDKEPC 720
Score = 45.8 bits (107), Expect = 7e-05
Identities = 52/242 (21%), Positives = 108/242 (44%), Gaps = 18/242 (7%)
Query: 88 QLVRNREQISVTLGD-----EMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIE 142
QL +++E + G+ + F +K + E K N+ ++L+ ++L + +
Sbjct: 477 QLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCSTQLESSLN 536
Query: 143 QMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNREL-KEAHEAELSELENNYKAALKAEKL 201
+ N Q Q L + E+ L+ + ++ L KE H + + + Y A L +
Sbjct: 537 KYNTSQQVIQDL-NKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDA-LSRKSA 594
Query: 202 AAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKK 261
A Q+ L + ++ ++ + ++ Q S+ E+K ++ +E+ ++ N L++ +
Sbjct: 595 ACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRG 654
Query: 262 MTKKFEMESGEEDKKINE-SCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEEL 320
++ E+E DKK+ E SC + + KQHQ+D L + QEE+
Sbjct: 655 FHQESELEVHAFDKKLEEMSCQVL---------QWQKQHQNDLKMLAAKEEQLREFQEEM 705
Query: 321 HA 322
A
Sbjct: 706 AA 707
Score = 31.2 bits (69), Expect = 1.9
Identities = 74/371 (19%), Positives = 164/371 (44%), Gaps = 45/371 (12%)
Query: 70 QEETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIPD-KGRFSRTN-II 127
QE NK + + + +++ ++ L E++ + + + I + + + + +N ++
Sbjct: 67 QEPENKGDHSKVRIYTSPCMIQEHQETQKRLS-EVWQKVSQQDDLIQELRNKLACSNALV 125
Query: 128 SDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSE 187
+ E+ + +L A H+ SSE C ++K+ ++ +E K++ + E
Sbjct: 126 LEREKALIKLQADFASCTATHRYPPS--SSE---ECEDIKKILKHL-QEQKDSQCLHVEE 179
Query: 188 LENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWS-----KQKAK 242
+N K L+ E A E+ + K+ L+ ++ +E K + + +
Sbjct: 180 YQNLVKD-LRVELEAVSEQKRNIMKDMMKLELDLHGLREETSAHIERKDKDITILQCRLQ 238
Query: 243 WKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSD 302
+ E E + + L++ K + +K EM E +KK+ + +N + +KE+ L++ Q
Sbjct: 239 ELQLEFTETQKLTLKKDKFLQEKDEMLQ-ELEKKLTQ-----VQNSLLKKEKELEKQQCM 292
Query: 303 TLQLE-ELRKTKEVMQEELHAQALILE------SLNTNLYYTQLELQ------KEKAIVG 349
+LE +++ K+ +E +AL E SL +L Q +E A+ G
Sbjct: 293 ATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAG 352
Query: 350 --------NLEK--MLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEICEGCSGRL 399
L+K +L + A+T ++ + +Q+L +E+ + +K + N + E S L
Sbjct: 353 CHLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKES-SMAEKEQTSNRKRVEELSLEL 411
Query: 400 ASITVSKDDSD 410
+ ++SD
Sbjct: 412 SEALRKLENSD 422
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 60.5 bits (145), Expect = 3e-09
Identities = 75/320 (23%), Positives = 155/320 (48%), Gaps = 41/320 (12%)
Query: 117 DKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRE 176
DK + ++ +LE++++++ + + ++ + Q+ +++E+++ E KQ+ ++K E
Sbjct: 400 DKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEK-QQCMATELEMTVKEAKQD-KSKEAE 457
Query: 177 LKEAHEAELSELENNYKAALKAEKLAAQEKL---EEMGKEYKYLKNMFRTYQDSIYDEME 233
K A +AE+ +L+N+ + A + E+LAAQ+ EE +L++ R Q +
Sbjct: 458 CK-ALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLL---- 512
Query: 234 EKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAV---FENFIQ 290
KQKA ++ +RE +LQ++ M +K + + + ++++ S EN +
Sbjct: 513 --LDKQKA--DTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSEALRKLENSDK 568
Query: 291 EKEELLK------QHQSDTL-----QLEELRKTKEVMQEELHAQALILESLNTNLYYTQL 339
EK +L K +D L Q E K ++E+L +LE L ++
Sbjct: 569 EKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLKKSK- 627
Query: 340 ELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEICEGCSGRL 399
+ EK + G LE + Q +F + ++ K + L EEN +L+ ++ + CS +L
Sbjct: 628 --EHEKLMEGELEALRQ-EFKKKDKTLKENSRKLEEENENLRAEL--------QCCSTQL 676
Query: 400 -ASITVSKDDSDTVQDGSKK 418
+S+ +QD +K+
Sbjct: 677 ESSLNKYNTSQQVIQDLNKE 696
Score = 48.1 bits (113), Expect = 1e-05
Identities = 65/309 (21%), Positives = 135/309 (43%), Gaps = 46/309 (14%)
Query: 102 DEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSA---QKLLSSE 158
++M DR K E + +I LEE + E T ++E + + +KL+ E
Sbjct: 585 NDMLDRIKHQHRE--------QGSIKCKLEEDLQEATKLLEDKREQLKKSKEHEKLMEGE 636
Query: 159 MDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLK 218
++ ++Q F+ K++ LKE E EN L+AE +LE +Y +
Sbjct: 637 LEA----LRQEFKKKDKTLKENSRKLEEENEN-----LRAELQCCSTQLESSLNKYNTSQ 687
Query: 219 NMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKIN 278
+ + I + E S Q + D+ ++E LQ +TK E+ + + +
Sbjct: 688 QVIQDLNKEIALQKESLMSLQA---QLDKALQKEKHYLQTT--ITK----EAYDALSRKS 738
Query: 279 ESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNL---- 334
+C +++ + + +S L + ++ K ++EE+ A ++ LNT L
Sbjct: 739 AACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLR 798
Query: 335 -YYTQLELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILT----------EENIHLKQK 383
++ + EL+ A LE+M + + ++++++ +++L EE LK+
Sbjct: 799 GFHQESELEVH-AFDKKLEEM-SCQVLQWQKQHQNDLKMLAAKEEQLREFQEEMAALKEN 856
Query: 384 IISKNEEIC 392
++ ++E C
Sbjct: 857 LLEDDKEPC 865
Score = 45.8 bits (107), Expect = 7e-05
Identities = 52/242 (21%), Positives = 108/242 (44%), Gaps = 18/242 (7%)
Query: 88 QLVRNREQISVTLGD-----EMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIE 142
QL +++E + G+ + F +K + E K N+ ++L+ ++L + +
Sbjct: 622 QLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCSTQLESSLN 681
Query: 143 QMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNREL-KEAHEAELSELENNYKAALKAEKL 201
+ N Q Q L + E+ L+ + ++ L KE H + + + Y A L +
Sbjct: 682 KYNTSQQVIQDL-NKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDA-LSRKSA 739
Query: 202 AAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKK 261
A Q+ L + ++ ++ + ++ Q S+ E+K ++ +E+ ++ N L++ +
Sbjct: 740 ACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRG 799
Query: 262 MTKKFEMESGEEDKKINE-SCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEEL 320
++ E+E DKK+ E SC + + KQHQ+D L + QEE+
Sbjct: 800 FHQESELEVHAFDKKLEEMSCQVL---------QWQKQHQNDLKMLAAKEEQLREFQEEM 850
Query: 321 HA 322
A
Sbjct: 851 AA 852
Score = 31.2 bits (69), Expect = 1.9
Identities = 74/371 (19%), Positives = 164/371 (44%), Gaps = 45/371 (12%)
Query: 70 QEETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIPD-KGRFSRTN-II 127
QE NK + + + +++ ++ L E++ + + + I + + + + +N ++
Sbjct: 212 QEPENKGDHSKVRIYTSPCMIQEHQETQKRLS-EVWQKVSQQDDLIQELRNKLACSNALV 270
Query: 128 SDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSE 187
+ E+ + +L A H+ SSE C ++K+ ++ +E K++ + E
Sbjct: 271 LEREKALIKLQADFASCTATHRYPPS--SSE---ECEDIKKILKHL-QEQKDSQCLHVEE 324
Query: 188 LENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWS-----KQKAK 242
+N K L+ E A E+ + K+ L+ ++ +E K + + +
Sbjct: 325 YQNLVKD-LRVELEAVSEQKRNIMKDMMKLELDLHGLREETSAHIERKDKDITILQCRLQ 383
Query: 243 WKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSD 302
+ E E + + L++ K + +K EM E +KK+ + +N + +KE+ L++ Q
Sbjct: 384 ELQLEFTETQKLTLKKDKFLQEKDEMLQ-ELEKKLTQ-----VQNSLLKKEKELEKQQCM 437
Query: 303 TLQLE-ELRKTKEVMQEELHAQALILE------SLNTNLYYTQLELQ------KEKAIVG 349
+LE +++ K+ +E +AL E SL +L Q +E A+ G
Sbjct: 438 ATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAG 497
Query: 350 --------NLEK--MLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEICEGCSGRL 399
L+K +L + A+T ++ + +Q+L +E+ + +K + N + E S L
Sbjct: 498 CHLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKES-SMAEKEQTSNRKRVEELSLEL 556
Query: 400 ASITVSKDDSD 410
+ ++SD
Sbjct: 557 SEALRKLENSD 567
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 60.5 bits (145), Expect = 3e-09
Identities = 80/323 (24%), Positives = 143/323 (44%), Gaps = 70/323 (21%)
Query: 130 LEEQISELTAIIEQMNRDHQS----------AQKLLSSEMDLRCAEMKQNFENKNRELKE 179
LE+ + EL+ EQ+ R Q+ A K LS+ DL+ + + K ELK
Sbjct: 530 LEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELK- 588
Query: 180 AHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQ 239
HEAE++ NYK L+ + L+ M + + RT + EE+ SK
Sbjct: 589 -HEAEVT----NYKIKLEMLEKEKNAVLDRMAESQEAELERLRT---QLLFSHEEELSKL 640
Query: 240 KAKWKKDEKFE----RENILLQQKKK-------MTKKFEMESGEEDKKINESCSAVFE-N 287
K + + + ++N+ + K++ M++K E E+D I + + E +
Sbjct: 641 KEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEIS 700
Query: 288 FIQEKEELLKQHQSD--TLQLEELRKTKEVMQEELHAQALILES-----LNTNLYYTQL- 339
+++ ++ L +S+ TLQ+ EL+K E++++E + + + L T L Q+
Sbjct: 701 KLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMK 760
Query: 340 -----------ELQKEKAIVGN----LEKMLQTKFAETEEK----------------YKH 368
+L+ E +I+ + LE ML+ ++E+ ++
Sbjct: 761 EKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEK 820
Query: 369 TIQILTEENIHLKQKIISKNEEI 391
I+IL EEN LKQ+ I NEEI
Sbjct: 821 EIEILIEENEDLKQQCIQLNEEI 843
Score = 51.6 bits (122), Expect = 1e-06
Identities = 53/251 (21%), Positives = 110/251 (43%), Gaps = 35/251 (13%)
Query: 143 QMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLA 202
Q RD ++ + ++ + + ++ ENKN E+++ H L+ +K
Sbjct: 2192 QAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLH------------MQLEIQKKE 2239
Query: 203 AQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKF--ERENILLQQKK 260
+ +L+E+ +E K K+ +I + Q + K + E+E + Q +
Sbjct: 2240 STTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNE 2299
Query: 261 KMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEEL 320
++TK + D K+ I+EK EL++ ++ Q+E L +E ++
Sbjct: 2300 QVTKLQQQLKITTDNKV-----------IEEKNELIRDLET---QIECLMSDQECVKRNR 2345
Query: 321 HAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHL 380
+ +E LN + +LQ+E A +G M +E + KH + ++ E + L
Sbjct: 2346 EEE---IEQLNEVIE----KLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLAL 2398
Query: 381 KQKIISKNEEI 391
+Q++ + NEE+
Sbjct: 2399 EQQVETANEEM 2409
Score = 50.8 bits (120), Expect = 2e-06
Identities = 72/344 (20%), Positives = 155/344 (45%), Gaps = 37/344 (10%)
Query: 65 IHSARQE--ETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIPDKGRFS 122
+ AR+E ET + F E+ S Q+ + Q S TL R S D + +
Sbjct: 214 LQQARREKDETMREFLELTEQSQKLQIQFQQLQASETL------RNSTHSSTAADLLQ-A 266
Query: 123 RTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMD-LRCAEMKQN--FENKNRELKE 179
+ I++ ++Q+ E ++E + + +S + ++ EM+Q+ EN N+E +
Sbjct: 267 KQQILTH-QQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQ 325
Query: 180 AHEAELSEL-----ENNYKAALKAEKLAAQEKL-----EEMGKEYKYLKNMFRTYQDSIY 229
E + EL E K +KL +KL E++ ++ + +KNM +S
Sbjct: 326 EKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQ 385
Query: 230 DEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVF-ENF 288
E + ++ +E +R + Q + + ++ E E+ + +++ ++ +
Sbjct: 386 KERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQI 445
Query: 289 IQEKEELLKQHQSDTLQLEELR-KTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAI 347
+Q K+EL++QH + Q+EE++ + K M+ L + +N+ + +++
Sbjct: 446 VQMKQELIRQHMA---QMEEMKTRHKGEMENALRSY--------SNITVNEDQIKLMNVA 494
Query: 348 VGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEI 391
+ L LQ ++ +EK K + ++ EE L++++ EE+
Sbjct: 495 INELNIKLQDTNSQ-KEKLKEELGLILEEKCALQRQLEDLVEEL 537
Score = 48.5 bits (114), Expect = 1e-05
Identities = 72/329 (21%), Positives = 144/329 (43%), Gaps = 38/329 (11%)
Query: 91 RNREQISVTLG------DEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQM 144
R REQ++V L D D K +E +I +K T+II LE+++ + ++++
Sbjct: 1908 RAREQLAVELSKAEGVIDGYADEKTLFERQIQEK-----TDIIDRLEQELLCASNRLQEL 1962
Query: 145 NRDHQSAQK---LLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKL 201
+ Q Q+ LLS + + AE + + L+E + +LE +A + L
Sbjct: 1963 EAEQQQIQEERELLSRQKEAMKAEAGPV---EQQLLQETEKLMKEKLEVQCQAEKVRDDL 2019
Query: 202 AAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQ--KAKWKKDEKFERENILLQQK 259
Q K E+ E + + Q+ + M+ + Q + + +K KF E + ++
Sbjct: 2020 QKQVKALEIDVE-EQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREH 2078
Query: 260 KKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEE 319
++ + E++ E+ K+ + E+ +E E+L + T + EL +KE +Q +
Sbjct: 2079 ERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRD 2138
Query: 320 LHAQALILESLNTNL------------YYTQLELQKEKAIVG-----NLEKMLQTKFAET 362
+ + +E L + + ++E +K V +LE LQ +
Sbjct: 2139 IQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAI 2198
Query: 363 EEKYKHTIQILTEENIHLKQKIISKNEEI 391
+ K K I L E+ ++++ +KNEE+
Sbjct: 2199 DRKEKE-ITNLEEQLEQFREELENKNEEV 2226
Score = 48.1 bits (113), Expect = 1e-05
Identities = 70/299 (23%), Positives = 127/299 (42%), Gaps = 53/299 (17%)
Query: 92 NREQISVTLG---DEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDH 148
N E++ LG + D + S+ + +F + N+I+ + I E++ + +
Sbjct: 651 NIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQ---- 706
Query: 149 QSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLE 208
QS S EM L+ E+++ E +E KE K L+ E Q K E
Sbjct: 707 QSLVNSKSEEMTLQINELQKEIEILRQEEKE-------------KGTLEQEVQELQLKTE 753
Query: 209 EMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKK----MTK 264
+ K+ K +N +++EK+++ E EN +L+ +KK M K
Sbjct: 754 LLEKQMKEKEN-----------DLQEKFAQ----------LEAENSILKDEKKTLEDMLK 792
Query: 265 KFEMESGEEDKKINESCSAVFENFIQEKE-ELLKQHQSDTLQLEELRKTKEVMQEELHAQ 323
S EE +S + ++ + EKE E+L + E+L++ + EE+ Q
Sbjct: 793 IHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEEN------EDLKQQCIQLNEEIEKQ 846
Query: 324 ALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQ 382
N ELQ+E A + ++ L+ + E +YK ++ L EE +HL++
Sbjct: 847 RNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEE-LHLQR 904
Score = 44.7 bits (104), Expect = 2e-04
Identities = 60/282 (21%), Positives = 133/282 (47%), Gaps = 23/282 (8%)
Query: 88 QLVRNREQISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRD 147
Q+++ +E L +++ +++ + +K + +I DLE QI L + E + R+
Sbjct: 2285 QIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRN 2344
Query: 148 HQSAQKLLSSEMDLRCAEMKQNFENKNRELK-EAHEAELSELENNYKAALK---AEKLAA 203
+ + L+ ++ +++Q N ++ AH LSE ++ K L AEKLA
Sbjct: 2345 REEEIEQLNEVIE----KLQQELANIGQKTSMNAHS--LSEEADSLKHQLDVVIAEKLAL 2398
Query: 204 QEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFE-----RENILLQQ 258
++++E +E ++KN+ + + +E +S ++ + + EK + N+ +
Sbjct: 2399 EQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRER-ESVEKIQSIPENSVNVAIDH 2457
Query: 259 KKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQE 318
K + E+ E+ K E+ F++F + + + ++ LQLE K++
Sbjct: 2458 LSKDKPELEVVLTEDALKSLEN-QTYFKSFEENGKGSIINLETRLLQLESTVSAKDLELT 2516
Query: 319 ELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFA 360
+ + Q I + + T++ LQK+ + NL+K+++ K A
Sbjct: 2517 QCYKQ--IKDMQEQGQFETEM-LQKK---IVNLQKIVEEKVA 2552
Score = 43.5 bits (101), Expect = 4e-04
Identities = 80/396 (20%), Positives = 153/396 (38%), Gaps = 73/396 (18%)
Query: 30 RKNSTGSSKLTPLVPAPKNHNYLQPTKPVVSPKMKIHSARQEETNKSFYEVINVSPGYQL 89
+K T SSK N + Q + ++ ++ S E+ ++ ++
Sbjct: 38 KKRKTSSSKHDVSAHHDLNIDQSQCNEMYINSSQRVESTVIPEST-----IMRTLHSGEI 92
Query: 90 VRNREQISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDL--EEQISELTAIIEQMNRD 147
+ + SV L E+ SE+ RT ++L EE+ + EQ +D
Sbjct: 93 TSHEQGFSVELESEISTTADDCSSEVNGCSFVMRTGKPTNLLREEEFGVDDSYSEQGAQD 152
Query: 148 HQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKL 207
+ +++ SE+ A + E NREL+E + E L ++
Sbjct: 153 SPTHLEMMESEL----AGKQHEIEELNRELEEM------------RVTYGTEGLQQLQEF 196
Query: 208 EEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFE 267
E K+ +D I ++ + Q+A+ +KDE L +Q +K+ +F+
Sbjct: 197 EAAIKQ-----------RDGIITQLTA--NLQQARREKDETMREFLELTEQSQKLQIQFQ 243
Query: 268 MESGEEDKKINESCSAVFENFIQEKEELL-----------------KQHQSDTLQL---- 306
E + N + S+ + +Q K+++L K+ + T+Q+
Sbjct: 244 QLQASETLR-NSTHSSTAADLLQAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQ 302
Query: 307 --------EELRKTKEVMQEELHAQALILESLNTNLYYTQ---LELQKEKAIVGNLEKML 355
E+ +K + +EE+ + I+E LNT + + LEL+ + L L
Sbjct: 303 EKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGEL 362
Query: 356 QTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEI 391
Q + + ++ K+ LT KQK +EEI
Sbjct: 363 QEQIVQKNQEIKNMKLELTNS----KQKERQSSEEI 394
Score = 43.5 bits (101), Expect = 4e-04
Identities = 55/287 (19%), Positives = 126/287 (43%), Gaps = 21/287 (7%)
Query: 88 QLVRNREQISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRD 147
+++R E+ TL E+ ++ + ++E+ +K + N DL+E+ ++L A + +
Sbjct: 729 EILRQEEKEKGTLEQEV--QELQLKTELLEKQMKEKEN---DLQEKFAQLEAENSILKDE 783
Query: 148 HQSAQKLLSSEMDLRCAE---MKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQ 204
++ + +L + E + ++K+++ E E+ EN LK + +
Sbjct: 784 KKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENE---DLKQQCIQLN 840
Query: 205 EKLEEMGKEYKYLKNMFRT-YQD---------SIYDEMEEKWSKQKAKWKKDEKFERENI 254
E++E+ + + + F YQ+ + D++E+ +KQ+ ++K K E +
Sbjct: 841 EEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEEL 900
Query: 255 LLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKE 314
LQ+ T K + +EDK + E ++ EL+++ + + EL +
Sbjct: 901 HLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLS 960
Query: 315 VMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAE 361
+ E+L + + LN + + E ++ LE ++ AE
Sbjct: 961 DLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINHNRAE 1007
Score = 42.0 bits (97), Expect = 0.001
Identities = 48/240 (20%), Positives = 106/240 (44%), Gaps = 17/240 (7%)
Query: 130 LEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELE 189
L+++I L I+E+ L S++ L + F N+ + E E + ++
Sbjct: 2536 LQKKIVNLQKIVEE------KVAAALVSQIQLEAVQEYAKFCQDNQTISS--EPERTNIQ 2587
Query: 190 NNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKF 249
N + L+ ++L + + + L++ S+ E E+ +K +K++K
Sbjct: 2588 NLNQ--LREDELGSD--ISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKL 2643
Query: 250 ERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFEN-----FIQEKEELLKQHQSDTL 304
LL+ +K ++ E + +D ++ ++ + +F + F E E L + +
Sbjct: 2644 LELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKA 2703
Query: 305 QLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAETEE 364
+L ++ E +QEEL + + SL +L + L + K + LEK +T+ E+++
Sbjct: 2704 ELASYKEKAEKLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKK 2763
Score = 39.3 bits (90), Expect = 0.007
Identities = 66/336 (19%), Positives = 146/336 (43%), Gaps = 37/336 (11%)
Query: 106 DRKKRWESEIPDKGRFSRTNIISDLEEQIS-ELTAIIEQMNRDHQSAQKLLSSEMDLRCA 164
++ K SE DK + ++Q + +L ++EQ + +Q+ + S+ L A
Sbjct: 3227 EKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDA 3286
Query: 165 EMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQ-EKLEEMGKEYKYLKNMFRT 223
++ + + +N EL+ E+E + + +L AQ + + G+ L +
Sbjct: 3287 QLSEE-QGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPS--ED 3343
Query: 224 YQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQK-------KKMTKKFEMESGEE-DK 275
+ ++EEK S+ + EK++ +++ +Q+ + T + E E+ E K
Sbjct: 3344 LLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQK 3403
Query: 276 KINESCSAV--FENFIQEKEE--------------LLKQHQSDTLQLEELRKTKEVMQEE 319
K++E S V + ++EK + ++++ Q L+ EE R+++ ++ +
Sbjct: 3404 KMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQN 3463
Query: 320 LHAQAL-ILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENI 378
L+ L S T + Q +++ E N K+++ T H ++++ ++
Sbjct: 3464 LNEPTTWSLTSDRTRNWVLQQKIEGETK-ESNYAKLIEMNGGGT--GCNHELEMIRQK-- 3518
Query: 379 HLKQKIISKNEEICEGCSGRLASITVSKDDSDTVQD 414
Q + SK + + + S RL T +D VQ+
Sbjct: 3519 --LQCVASKLQVLPQKASERLQFETADDEDFIWVQE 3552
Score = 36.6 bits (83), Expect = 0.044
Identities = 43/219 (19%), Positives = 94/219 (42%), Gaps = 32/219 (14%)
Query: 125 NIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAE 184
N IS L++ I+++ E D + + S ++Q F + L A E
Sbjct: 2989 NTISSLKDLITKMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTE 3048
Query: 185 LSELENNYKAALKAEKLAAQEKLEEMGKEYKY-LKNMFRTYQDSIYDEMEEKWSKQKAKW 243
L+ L L +++++E G EY+ ++ + + + S+ E++ ++ +
Sbjct: 3049 LTALGTTDAVGLLN---CLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGR- 3104
Query: 244 KKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDT 303
K+T K E ES + +++ E IQ+K+ + + Q
Sbjct: 3105 -----------------KITLKREQESEKPSQEL-------LEYNIQQKQSQMLEMQ--- 3137
Query: 304 LQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQ 342
++L ++ +QE+L ++ +++ L + L T+LEL+
Sbjct: 3138 VELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELE 3176
Score = 35.0 bits (79), Expect = 0.13
Identities = 43/182 (23%), Positives = 84/182 (46%), Gaps = 16/182 (8%)
Query: 98 VTLGDEMFDRKKRW--ESEIPDKGRFSRTNIISDL---EEQISELTAIIEQMNRDHQSAQ 152
+T+ +EMF + K + I D+ S + L EEQ+ ++ + + ++HQ A
Sbjct: 1546 LTISEEMFSKDKTFIVRQSIHDEISVSSMDASRQLMLNEEQLEDMRQELVRQYQEHQQAT 1605
Query: 153 KLLSSEMDLRCAEMKQNFENKNRELKEAHE--AELSELEN----NYKAALKAEKLAAQEK 206
+LL + +++ E E+K + A+ S ++N + + + E+L A ++
Sbjct: 1606 ELLRQAHMRQMERQREDQEQLQEEIKRLNRQLAQRSSIDNENLVSERERVLLEELEALKQ 1665
Query: 207 LEEMGKEYK--YLKNMFRTYQDSIYD--EMEEKWSKQKAKWKKDEKFERENILLQQKKKM 262
L G+E L+N Q+ + E+EE+ K+K +K E E IL ++ +
Sbjct: 1666 LSLAGREKLCCELRNSSTQTQNGNENQGEVEEQTFKEKELDRKPEDVPPE-ILSNERYAL 1724
Query: 263 TK 264
K
Sbjct: 1725 QK 1726
Score = 34.7 bits (78), Expect = 0.17
Identities = 44/175 (25%), Positives = 80/175 (45%), Gaps = 13/175 (7%)
Query: 186 SELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKK 245
S L Y ALK E + A++K E +Y +N QD Y+ + + + K
Sbjct: 1208 SVLGEYYTPALKCE-VNAEDK--ENSGDY-ISENEDPELQDYRYEVQDFQENMHTLLNKV 1263
Query: 246 DEKFERENILLQQKKKM----TKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQS 301
E++ + +L + K+ T ++E GEE+ E+ + + E++ H+S
Sbjct: 1264 TEEYNKLLVLQTRLSKIWGQQTDGMKLEFGEENLPKEETEFLSIHSQMTNLEDIDVNHKS 1323
Query: 302 DTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQ 356
L++L KTK ++E++ ++ SL L T+ Q +A + L+K LQ
Sbjct: 1324 KLSSLQDLEKTK--LEEQVQELESLISSLQQQLKETE---QNYEAEIHCLQKRLQ 1373
Score = 32.3 bits (72), Expect = 0.83
Identities = 45/224 (20%), Positives = 96/224 (42%), Gaps = 29/224 (12%)
Query: 128 SDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSE 187
+D +SE+ A+ QMN + ++ SE + ++ N + K ++ E + ELS
Sbjct: 3085 ADRRSLLSEIQALHAQMNGRKITLKREQESEKPSQ-ELLEYNIQQKQSQMLEM-QVELSS 3142
Query: 188 LENN---YKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWK 244
+++ + L +EK+ E E+ + L+ + Q E+E + + K K
Sbjct: 3143 MKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKA-QHKHLKELEA--FRLEVKDK 3199
Query: 245 KDE-KFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDT 303
DE + + +QKK ++ +E +EK +L + + D
Sbjct: 3200 TDEVHLLNDTLASEQKKSRELQWALE--------------------KEKAKLGRSEERDK 3239
Query: 304 LQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAI 347
+LE+L+ + E ++ L+LE L +Q +++ ++ +
Sbjct: 3240 EELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRML 3283
Score = 28.9 bits (63), Expect = 9.2
Identities = 62/317 (19%), Positives = 123/317 (38%), Gaps = 44/317 (13%)
Query: 108 KKRWESEIPDKGRFS---RTNIISDLE----EQISELTAII-----------EQMNRDHQ 149
KK + I G F TNI+ LE EQ+ E A + +++R
Sbjct: 1407 KKNIDGTIEFSGEFGVKEETNIVKLLEKQYQEQLEEEVAKVIVSMSIAFAQQTELSRISG 1466
Query: 150 SAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEE 209
+ SS+ + +Q++ N E+K + + + K E ++L E
Sbjct: 1467 GKENTASSKQAHAVCQQEQHYFN---EMKLSQDQIGFQTFETVDVKFKEEFKPLSKELGE 1523
Query: 210 MGKEYKYLKNM----FRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKK 265
GKE L N +D + EE +SK K + + ++ +
Sbjct: 1524 HGKEI-LLSNSDPHDIPESKDCVLTISEEMFSKDKTFIVRQSIHDEISVSSMDASRQL-- 1580
Query: 266 FEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELH---- 321
M + E+ + + + ++ Q E L + H Q+E R+ +E +QEE+
Sbjct: 1581 --MLNEEQLEDMRQELVRQYQEHQQATELLRQAHMR---QMERQREDQEQLQEEIKRLNR 1635
Query: 322 --AQALILESLNT-----NLYYTQLELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILT 374
AQ +++ N + +LE K+ ++ G + + + + T+ + + Q
Sbjct: 1636 QLAQRSSIDNENLVSERERVLLEELEALKQLSLAGREKLCCELRNSSTQTQNGNENQGEV 1695
Query: 375 EENIHLKQKIISKNEEI 391
EE ++++ K E++
Sbjct: 1696 EEQTFKEKELDRKPEDV 1712
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 60.5 bits (145), Expect = 3e-09
Identities = 80/323 (24%), Positives = 143/323 (44%), Gaps = 70/323 (21%)
Query: 130 LEEQISELTAIIEQMNRDHQS----------AQKLLSSEMDLRCAEMKQNFENKNRELKE 179
LE+ + EL+ EQ+ R Q+ A K LS+ DL+ + + K ELK
Sbjct: 530 LEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELK- 588
Query: 180 AHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQ 239
HEAE++ NYK L+ + L+ M + + RT + EE+ SK
Sbjct: 589 -HEAEVT----NYKIKLEMLEKEKNAVLDRMAESQEAELERLRT---QLLFSHEEELSKL 640
Query: 240 KAKWKKDEKFE----RENILLQQKKK-------MTKKFEMESGEEDKKINESCSAVFE-N 287
K + + + ++N+ + K++ M++K E E+D I + + E +
Sbjct: 641 KEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEIS 700
Query: 288 FIQEKEELLKQHQSD--TLQLEELRKTKEVMQEELHAQALILES-----LNTNLYYTQL- 339
+++ ++ L +S+ TLQ+ EL+K E++++E + + + L T L Q+
Sbjct: 701 KLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMK 760
Query: 340 -----------ELQKEKAIVGN----LEKMLQTKFAETEEK----------------YKH 368
+L+ E +I+ + LE ML+ ++E+ ++
Sbjct: 761 EKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEK 820
Query: 369 TIQILTEENIHLKQKIISKNEEI 391
I+IL EEN LKQ+ I NEEI
Sbjct: 821 EIEILIEENEDLKQQCIQLNEEI 843
Score = 51.6 bits (122), Expect = 1e-06
Identities = 53/251 (21%), Positives = 110/251 (43%), Gaps = 35/251 (13%)
Query: 143 QMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLA 202
Q RD ++ + ++ + + ++ ENKN E+++ H L+ +K
Sbjct: 2184 QAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLH------------MQLEIQKKE 2231
Query: 203 AQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKF--ERENILLQQKK 260
+ +L+E+ +E K K+ +I + Q + K + E+E + Q +
Sbjct: 2232 STTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNE 2291
Query: 261 KMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEEL 320
++TK + D K+ I+EK EL++ ++ Q+E L +E ++
Sbjct: 2292 QVTKLQQQLKITTDNKV-----------IEEKNELIRDLET---QIECLMSDQECVKRNR 2337
Query: 321 HAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHL 380
+ +E LN + +LQ+E A +G M +E + KH + ++ E + L
Sbjct: 2338 EEE---IEQLNEVIE----KLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLAL 2390
Query: 381 KQKIISKNEEI 391
+Q++ + NEE+
Sbjct: 2391 EQQVETANEEM 2401
Score = 50.8 bits (120), Expect = 2e-06
Identities = 72/344 (20%), Positives = 155/344 (45%), Gaps = 37/344 (10%)
Query: 65 IHSARQE--ETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIPDKGRFS 122
+ AR+E ET + F E+ S Q+ + Q S TL R S D + +
Sbjct: 214 LQQARREKDETMREFLELTEQSQKLQIQFQQLQASETL------RNSTHSSTAADLLQ-A 266
Query: 123 RTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMD-LRCAEMKQN--FENKNRELKE 179
+ I++ ++Q+ E ++E + + +S + ++ EM+Q+ EN N+E +
Sbjct: 267 KQQILTH-QQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQ 325
Query: 180 AHEAELSEL-----ENNYKAALKAEKLAAQEKL-----EEMGKEYKYLKNMFRTYQDSIY 229
E + EL E K +KL +KL E++ ++ + +KNM +S
Sbjct: 326 EKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQ 385
Query: 230 DEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVF-ENF 288
E + ++ +E +R + Q + + ++ E E+ + +++ ++ +
Sbjct: 386 KERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQI 445
Query: 289 IQEKEELLKQHQSDTLQLEELR-KTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAI 347
+Q K+EL++QH + Q+EE++ + K M+ L + +N+ + +++
Sbjct: 446 VQMKQELIRQHMA---QMEEMKTRHKGEMENALRSY--------SNITVNEDQIKLMNVA 494
Query: 348 VGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEI 391
+ L LQ ++ +EK K + ++ EE L++++ EE+
Sbjct: 495 INELNIKLQDTNSQ-KEKLKEELGLILEEKCALQRQLEDLVEEL 537
Score = 50.8 bits (120), Expect = 2e-06
Identities = 72/321 (22%), Positives = 143/321 (44%), Gaps = 30/321 (9%)
Query: 91 RNREQISVTLG------DEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQM 144
R REQ++V L D D K +E +I +K T+II LE+++ + ++++
Sbjct: 1908 RAREQLAVELSKAEGVIDGYADEKTLFERQIQEK-----TDIIDRLEQELLCASNRLQEL 1962
Query: 145 NRDHQSAQK---LLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKL 201
+ Q Q+ LLS + + AE + + L+E + +LE +A + L
Sbjct: 1963 EAEQQQIQEERELLSRQKEAMKAEAGPV---EQQLLQETEKLMKEKLEVQCQAEKVRDDL 2019
Query: 202 AAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQ--KAKWKKDEKFERENILLQQK 259
Q K E+ E + + Q+ + M+ + Q + + +K KF E + ++
Sbjct: 2020 QKQVKALEIDVE-EQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREH 2078
Query: 260 KKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEE 319
++ + E++ E+ K+ + E+ +E E+L + T + EL +KE +Q +
Sbjct: 2079 ERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRD 2138
Query: 320 LHAQALILESLNTNL-YYTQLELQKEKAIVG--------NLEKMLQTKFAETEEKYKHTI 370
+ + +E L + Q L +++ G +LE LQ + + K K I
Sbjct: 2139 IQERNEEIEKLEFRVRELEQALLVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKE-I 2197
Query: 371 QILTEENIHLKQKIISKNEEI 391
L E+ ++++ +KNEE+
Sbjct: 2198 TNLEEQLEQFREELENKNEEV 2218
Score = 48.1 bits (113), Expect = 1e-05
Identities = 70/299 (23%), Positives = 127/299 (42%), Gaps = 53/299 (17%)
Query: 92 NREQISVTLG---DEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDH 148
N E++ LG + D + S+ + +F + N+I+ + I E++ + +
Sbjct: 651 NIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQ---- 706
Query: 149 QSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLE 208
QS S EM L+ E+++ E +E KE K L+ E Q K E
Sbjct: 707 QSLVNSKSEEMTLQINELQKEIEILRQEEKE-------------KGTLEQEVQELQLKTE 753
Query: 209 EMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKK----MTK 264
+ K+ K +N +++EK+++ E EN +L+ +KK M K
Sbjct: 754 LLEKQMKEKEN-----------DLQEKFAQ----------LEAENSILKDEKKTLEDMLK 792
Query: 265 KFEMESGEEDKKINESCSAVFENFIQEKE-ELLKQHQSDTLQLEELRKTKEVMQEELHAQ 323
S EE +S + ++ + EKE E+L + E+L++ + EE+ Q
Sbjct: 793 IHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEEN------EDLKQQCIQLNEEIEKQ 846
Query: 324 ALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQ 382
N ELQ+E A + ++ L+ + E +YK ++ L EE +HL++
Sbjct: 847 RNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEE-LHLQR 904
Score = 44.7 bits (104), Expect = 2e-04
Identities = 60/282 (21%), Positives = 133/282 (47%), Gaps = 23/282 (8%)
Query: 88 QLVRNREQISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRD 147
Q+++ +E L +++ +++ + +K + +I DLE QI L + E + R+
Sbjct: 2277 QIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRN 2336
Query: 148 HQSAQKLLSSEMDLRCAEMKQNFENKNRELK-EAHEAELSELENNYKAALK---AEKLAA 203
+ + L+ ++ +++Q N ++ AH LSE ++ K L AEKLA
Sbjct: 2337 REEEIEQLNEVIE----KLQQELANIGQKTSMNAHS--LSEEADSLKHQLDVVIAEKLAL 2390
Query: 204 QEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFE-----RENILLQQ 258
++++E +E ++KN+ + + +E +S ++ + + EK + N+ +
Sbjct: 2391 EQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRER-ESVEKIQSIPENSVNVAIDH 2449
Query: 259 KKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQE 318
K + E+ E+ K E+ F++F + + + ++ LQLE K++
Sbjct: 2450 LSKDKPELEVVLTEDALKSLEN-QTYFKSFEENGKGSIINLETRLLQLESTVSAKDLELT 2508
Query: 319 ELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFA 360
+ + Q I + + T++ LQK+ + NL+K+++ K A
Sbjct: 2509 QCYKQ--IKDMQEQGQFETEM-LQKK---IVNLQKIVEEKVA 2544
Score = 43.5 bits (101), Expect = 4e-04
Identities = 80/396 (20%), Positives = 153/396 (38%), Gaps = 73/396 (18%)
Query: 30 RKNSTGSSKLTPLVPAPKNHNYLQPTKPVVSPKMKIHSARQEETNKSFYEVINVSPGYQL 89
+K T SSK N + Q + ++ ++ S E+ ++ ++
Sbjct: 38 KKRKTSSSKHDVSAHHDLNIDQSQCNEMYINSSQRVESTVIPEST-----IMRTLHSGEI 92
Query: 90 VRNREQISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDL--EEQISELTAIIEQMNRD 147
+ + SV L E+ SE+ RT ++L EE+ + EQ +D
Sbjct: 93 TSHEQGFSVELESEISTTADDCSSEVNGCSFVMRTGKPTNLLREEEFGVDDSYSEQGAQD 152
Query: 148 HQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKL 207
+ +++ SE+ A + E NREL+E + E L ++
Sbjct: 153 SPTHLEMMESEL----AGKQHEIEELNRELEEM------------RVTYGTEGLQQLQEF 196
Query: 208 EEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFE 267
E K+ +D I ++ + Q+A+ +KDE L +Q +K+ +F+
Sbjct: 197 EAAIKQ-----------RDGIITQLTA--NLQQARREKDETMREFLELTEQSQKLQIQFQ 243
Query: 268 MESGEEDKKINESCSAVFENFIQEKEELL-----------------KQHQSDTLQL---- 306
E + N + S+ + +Q K+++L K+ + T+Q+
Sbjct: 244 QLQASETLR-NSTHSSTAADLLQAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQ 302
Query: 307 --------EELRKTKEVMQEELHAQALILESLNTNLYYTQ---LELQKEKAIVGNLEKML 355
E+ +K + +EE+ + I+E LNT + + LEL+ + L L
Sbjct: 303 EKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGEL 362
Query: 356 QTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEI 391
Q + + ++ K+ LT KQK +EEI
Sbjct: 363 QEQIVQKNQEIKNMKLELTNS----KQKERQSSEEI 394
Score = 43.5 bits (101), Expect = 4e-04
Identities = 55/287 (19%), Positives = 126/287 (43%), Gaps = 21/287 (7%)
Query: 88 QLVRNREQISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRD 147
+++R E+ TL E+ ++ + ++E+ +K + N DL+E+ ++L A + +
Sbjct: 729 EILRQEEKEKGTLEQEV--QELQLKTELLEKQMKEKEN---DLQEKFAQLEAENSILKDE 783
Query: 148 HQSAQKLLSSEMDLRCAE---MKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQ 204
++ + +L + E + ++K+++ E E+ EN LK + +
Sbjct: 784 KKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENE---DLKQQCIQLN 840
Query: 205 EKLEEMGKEYKYLKNMFRT-YQD---------SIYDEMEEKWSKQKAKWKKDEKFERENI 254
E++E+ + + + F YQ+ + D++E+ +KQ+ ++K K E +
Sbjct: 841 EEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEEL 900
Query: 255 LLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKE 314
LQ+ T K + +EDK + E ++ EL+++ + + EL +
Sbjct: 901 HLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLS 960
Query: 315 VMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAE 361
+ E+L + + LN + + E ++ LE ++ AE
Sbjct: 961 DLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINHNRAE 1007
Score = 42.0 bits (97), Expect = 0.001
Identities = 48/240 (20%), Positives = 106/240 (44%), Gaps = 17/240 (7%)
Query: 130 LEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELE 189
L+++I L I+E+ L S++ L + F N+ + E E + ++
Sbjct: 2528 LQKKIVNLQKIVEE------KVAAALVSQIQLEAVQEYAKFCQDNQTISS--EPERTNIQ 2579
Query: 190 NNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKF 249
N + L+ ++L + + + L++ S+ E E+ +K +K++K
Sbjct: 2580 NLNQ--LREDELGSD--ISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKL 2635
Query: 250 ERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFEN-----FIQEKEELLKQHQSDTL 304
LL+ +K ++ E + +D ++ ++ + +F + F E E L + +
Sbjct: 2636 LELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKA 2695
Query: 305 QLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAETEE 364
+L ++ E +QEEL + + SL +L + L + K + LEK +T+ E+++
Sbjct: 2696 ELASYKEKAEKLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKK 2755
Score = 39.3 bits (90), Expect = 0.007
Identities = 66/336 (19%), Positives = 146/336 (43%), Gaps = 37/336 (11%)
Query: 106 DRKKRWESEIPDKGRFSRTNIISDLEEQIS-ELTAIIEQMNRDHQSAQKLLSSEMDLRCA 164
++ K SE DK + ++Q + +L ++EQ + +Q+ + S+ L A
Sbjct: 3219 EKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDA 3278
Query: 165 EMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQ-EKLEEMGKEYKYLKNMFRT 223
++ + + +N EL+ E+E + + +L AQ + + G+ L +
Sbjct: 3279 QLSEE-QGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPS--ED 3335
Query: 224 YQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQK-------KKMTKKFEMESGEE-DK 275
+ ++EEK S+ + EK++ +++ +Q+ + T + E E+ E K
Sbjct: 3336 LLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQK 3395
Query: 276 KINESCSAV--FENFIQEKEE--------------LLKQHQSDTLQLEELRKTKEVMQEE 319
K++E S V + ++EK + ++++ Q L+ EE R+++ ++ +
Sbjct: 3396 KMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQN 3455
Query: 320 LHAQAL-ILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENI 378
L+ L S T + Q +++ E N K+++ T H ++++ ++
Sbjct: 3456 LNEPTTWSLTSDRTRNWVLQQKIEGETK-ESNYAKLIEMNGGGT--GCNHELEMIRQK-- 3510
Query: 379 HLKQKIISKNEEICEGCSGRLASITVSKDDSDTVQD 414
Q + SK + + + S RL T +D VQ+
Sbjct: 3511 --LQCVASKLQVLPQKASERLQFETADDEDFIWVQE 3544
Score = 36.6 bits (83), Expect = 0.044
Identities = 43/219 (19%), Positives = 94/219 (42%), Gaps = 32/219 (14%)
Query: 125 NIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAE 184
N IS L++ I+++ E D + + S ++Q F + L A E
Sbjct: 2981 NTISSLKDLITKMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTE 3040
Query: 185 LSELENNYKAALKAEKLAAQEKLEEMGKEYKY-LKNMFRTYQDSIYDEMEEKWSKQKAKW 243
L+ L L +++++E G EY+ ++ + + + S+ E++ ++ +
Sbjct: 3041 LTALGTTDAVGLLN---CLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGR- 3096
Query: 244 KKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDT 303
K+T K E ES + +++ E IQ+K+ + + Q
Sbjct: 3097 -----------------KITLKREQESEKPSQEL-------LEYNIQQKQSQMLEMQ--- 3129
Query: 304 LQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQ 342
++L ++ +QE+L ++ +++ L + L T+LEL+
Sbjct: 3130 VELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELE 3168
Score = 35.0 bits (79), Expect = 0.13
Identities = 43/182 (23%), Positives = 84/182 (46%), Gaps = 16/182 (8%)
Query: 98 VTLGDEMFDRKKRW--ESEIPDKGRFSRTNIISDL---EEQISELTAIIEQMNRDHQSAQ 152
+T+ +EMF + K + I D+ S + L EEQ+ ++ + + ++HQ A
Sbjct: 1546 LTISEEMFSKDKTFIVRQSIHDEISVSSMDASRQLMLNEEQLEDMRQELVRQYQEHQQAT 1605
Query: 153 KLLSSEMDLRCAEMKQNFENKNRELKEAHE--AELSELEN----NYKAALKAEKLAAQEK 206
+LL + +++ E E+K + A+ S ++N + + + E+L A ++
Sbjct: 1606 ELLRQAHMRQMERQREDQEQLQEEIKRLNRQLAQRSSIDNENLVSERERVLLEELEALKQ 1665
Query: 207 LEEMGKEYK--YLKNMFRTYQDSIYD--EMEEKWSKQKAKWKKDEKFERENILLQQKKKM 262
L G+E L+N Q+ + E+EE+ K+K +K E E IL ++ +
Sbjct: 1666 LSLAGREKLCCELRNSSTQTQNGNENQGEVEEQTFKEKELDRKPEDVPPE-ILSNERYAL 1724
Query: 263 TK 264
K
Sbjct: 1725 QK 1726
Score = 34.7 bits (78), Expect = 0.17
Identities = 44/175 (25%), Positives = 80/175 (45%), Gaps = 13/175 (7%)
Query: 186 SELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKK 245
S L Y ALK E + A++K E +Y +N QD Y+ + + + K
Sbjct: 1208 SVLGEYYTPALKCE-VNAEDK--ENSGDY-ISENEDPELQDYRYEVQDFQENMHTLLNKV 1263
Query: 246 DEKFERENILLQQKKKM----TKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQS 301
E++ + +L + K+ T ++E GEE+ E+ + + E++ H+S
Sbjct: 1264 TEEYNKLLVLQTRLSKIWGQQTDGMKLEFGEENLPKEETEFLSIHSQMTNLEDIDVNHKS 1323
Query: 302 DTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQ 356
L++L KTK ++E++ ++ SL L T+ Q +A + L+K LQ
Sbjct: 1324 KLSSLQDLEKTK--LEEQVQELESLISSLQQQLKETE---QNYEAEIHCLQKRLQ 1373
Score = 32.3 bits (72), Expect = 0.83
Identities = 45/224 (20%), Positives = 96/224 (42%), Gaps = 29/224 (12%)
Query: 128 SDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSE 187
+D +SE+ A+ QMN + ++ SE + ++ N + K ++ E + ELS
Sbjct: 3077 ADRRSLLSEIQALHAQMNGRKITLKREQESEKPSQ-ELLEYNIQQKQSQMLEM-QVELSS 3134
Query: 188 LENN---YKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWK 244
+++ + L +EK+ E E+ + L+ + Q E+E + + K K
Sbjct: 3135 MKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKA-QHKHLKELEA--FRLEVKDK 3191
Query: 245 KDE-KFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDT 303
DE + + +QKK ++ +E +EK +L + + D
Sbjct: 3192 TDEVHLLNDTLASEQKKSRELQWALE--------------------KEKAKLGRSEERDK 3231
Query: 304 LQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAI 347
+LE+L+ + E ++ L+LE L +Q +++ ++ +
Sbjct: 3232 EELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRML 3275
Score = 28.9 bits (63), Expect = 9.2
Identities = 62/317 (19%), Positives = 123/317 (38%), Gaps = 44/317 (13%)
Query: 108 KKRWESEIPDKGRFS---RTNIISDLE----EQISELTAII-----------EQMNRDHQ 149
KK + I G F TNI+ LE EQ+ E A + +++R
Sbjct: 1407 KKNIDGTIEFSGEFGVKEETNIVKLLEKQYQEQLEEEVAKVIVSMSIAFAQQTELSRISG 1466
Query: 150 SAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEE 209
+ SS+ + +Q++ N E+K + + + K E ++L E
Sbjct: 1467 GKENTASSKQAHAVCQQEQHYFN---EMKLSQDQIGFQTFETVDVKFKEEFKPLSKELGE 1523
Query: 210 MGKEYKYLKNM----FRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKK 265
GKE L N +D + EE +SK K + + ++ +
Sbjct: 1524 HGKEI-LLSNSDPHDIPESKDCVLTISEEMFSKDKTFIVRQSIHDEISVSSMDASRQL-- 1580
Query: 266 FEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELH---- 321
M + E+ + + + ++ Q E L + H Q+E R+ +E +QEE+
Sbjct: 1581 --MLNEEQLEDMRQELVRQYQEHQQATELLRQAHMR---QMERQREDQEQLQEEIKRLNR 1635
Query: 322 --AQALILESLNT-----NLYYTQLELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILT 374
AQ +++ N + +LE K+ ++ G + + + + T+ + + Q
Sbjct: 1636 QLAQRSSIDNENLVSERERVLLEELEALKQLSLAGREKLCCELRNSSTQTQNGNENQGEV 1695
Query: 375 EENIHLKQKIISKNEEI 391
EE ++++ K E++
Sbjct: 1696 EEQTFKEKELDRKPEDV 1712
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 60.1 bits (144), Expect = 4e-09
Identities = 38/202 (18%), Positives = 100/202 (49%), Gaps = 13/202 (6%)
Query: 131 EEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELEN 190
EEQ+ E +++ Q ++ + + + + +Q E + + LK+ + E E
Sbjct: 233 EEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTG 292
Query: 191 NYKAALKAEKLAAQEKLEEMGKEYKYLKNM---FRTYQDSIYDEMEEKWSKQKAKWKKDE 247
+ ++ ++ +E+ E+M ++ + ++ ++ ++++ E+ W +++ WK++E
Sbjct: 293 EQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEE 352
Query: 248 KF-ERENILLQQKKKMTKKFEMESGEED---------KKINESCSAVFENFIQEKEELLK 297
+ E+E + +Q++++ K+ E +E+ +K E E ++KE++ +
Sbjct: 353 QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMRE 412
Query: 298 QHQSDTLQLEELRKTKEVMQEE 319
Q + Q E++RK +E M E+
Sbjct: 413 QEEQMGEQKEQMRKQEEHMGEQ 434
Score = 46.6 bits (109), Expect = 4e-05
Identities = 46/268 (17%), Positives = 125/268 (46%), Gaps = 17/268 (6%)
Query: 127 ISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELS 186
+ + E Q+ E + + Q+ E + + E ++ + + ++ E E
Sbjct: 173 VREQEGQVREQEGQVREQE-GQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRK 231
Query: 187 ELEN--NYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWK 244
+ E + ++ ++ Q++ E+M K+ + ++ Q+ E EE+ KQK + +
Sbjct: 232 QEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMRE-----QEEQMREQEEQMLKQKEQTE 286
Query: 245 KDEKF-ERENILLQQKKKMTKKFEM--ESGEEDKKINESCSAVFENFIQEKEELLKQHQS 301
++E+ E+E + +Q+++M ++ E E E+ ++ E E ++KE++ +Q +
Sbjct: 287 QEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQ 346
Query: 302 DTLQLEELRKTKEVMQ---EELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKML--- 355
Q E++ + +E MQ E++ Q + + + +++K++ +G ++ +
Sbjct: 347 MWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQ 406
Query: 356 QTKFAETEEKYKHTIQILTEENIHLKQK 383
+ + E EE+ + + ++ H+ ++
Sbjct: 407 KEQMREQEEQMGEQKEQMRKQEEHMGEQ 434
Score = 37.4 bits (85), Expect = 0.026
Identities = 35/192 (18%), Positives = 97/192 (50%), Gaps = 27/192 (14%)
Query: 205 EKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKW-KKDEKFERENILLQQKKKMT 263
E+ E+MG++ + ++ Q+ E EE+ KQ+ + +++E+ +++ +Q++++
Sbjct: 203 EQEEQMGEQEEQMQK-----QEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQM 257
Query: 264 KKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQ 323
+K E + E+++++ +E+EE + + + T Q E+ + +E M+E Q
Sbjct: 258 RKQEEQMREQEEQM------------REQEEQMLKQKEQTEQEEQTGEQEEQMRE----Q 301
Query: 324 ALILESLNTNLYYTQLELQKEKAIVGNLEKML----QTKFAETEEKYKHTIQI-LTEENI 378
+ + + ++++++ +G E+ + + + + E+ +K Q+ EE +
Sbjct: 302 EEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQM 361
Query: 379 HLKQKIISKNEE 390
+++ + K EE
Sbjct: 362 QKQEEQVRKQEE 373
>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
Length = 898
Score = 59.7 bits (143), Expect = 5e-09
Identities = 79/342 (23%), Positives = 141/342 (41%), Gaps = 66/342 (19%)
Query: 108 KKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRC-AEM 166
KKR E+E N I LE +I EL ++ +RD AQ + + + EM
Sbjct: 238 KKRTETEK------QHMNTIKQLESRIEELNKEVKA-SRDQLIAQDVTAKNAVQQLHKEM 290
Query: 167 KQNFENKNRELKEAH---EAELSELENNYKAAL--KAEKLAAQEKLEEMGKEYKYLKNMF 221
Q E N++ +EA EA + + K +L + EK ++KL + KE + N
Sbjct: 291 AQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKI 350
Query: 222 RTYQDS------IY--------------DEMEE---------KWSKQKAKWKKDEKFERE 252
+ +Y D+++E KW++ K K + D E +
Sbjct: 351 KQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETK 410
Query: 253 NILLQQKKKMTK---------------------KFEMESGEEDKKINESCSAVFENFIQE 291
+ L + K+T+ E++S E D K+ + E +QE
Sbjct: 411 DKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVT-KGELEKQMQE 469
Query: 292 KEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNL 351
K + L+ H + +LE+L++T + +EL ++ L T+ EL K K I+
Sbjct: 470 KSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQ 529
Query: 352 EKMLQTKF--AETEEKYKHTIQILTEENIHLKQKIISKNEEI 391
+ +Q +T ++ + +Q +E +LK+++ S N I
Sbjct: 530 KAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVESLNSLI 571
Score = 38.9 bits (89), Expect = 0.009
Identities = 46/227 (20%), Positives = 102/227 (44%), Gaps = 22/227 (9%)
Query: 145 NRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELK--EAHEAELSELENNYKAA---LKAE 199
N+ HQ + SE D E+K+ E + + + + E+ + EL KA+ L A+
Sbjct: 216 NKKHQELFVDICSEKDNLREELKKRTETEKQHMNTIKQLESRIEELNKEVKASRDQLIAQ 275
Query: 200 KLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENI-LLQQ 258
+ A+ ++++ KE + + EE +++A K + E+E++ L ++
Sbjct: 276 DVTAKNAVQQLHKE-------MAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKE 328
Query: 259 KKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQE 318
K+ + KK + E +K N+ + QEK L + +++ + L + + ++E
Sbjct: 329 KETLEKKLRDANKELEKNTNK-----IKQLSQEKGRLHQLYETKEGETTRLIREIDKLKE 383
Query: 319 ELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAETEEK 365
++++ + ++ L + E+ K L K TK + +E+
Sbjct: 384 DINSHVIKVKWAQNKL---KAEMDSHKETKDKL-KETTTKLTQAKEE 426
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 59.3 bits (142), Expect = 6e-09
Identities = 75/330 (22%), Positives = 148/330 (44%), Gaps = 42/330 (12%)
Query: 95 QISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSA--- 151
+++ L D++ D K ++E + G+ L QI + I+E+ RD
Sbjct: 524 RLTEELKDQLKDLKVKYEGASAEVGK---------LRNQIKQNEMIVEEFKRDEGKLIEE 574
Query: 152 QKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKL--EE 209
K L E+ + EM++ E K R++ E E + EL ++ AEK + E
Sbjct: 575 NKRLQKELSM--CEMER--EKKGRKVTEM-EGQAKELSAKLALSIPAEKFENMKSSLSNE 629
Query: 210 MGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEME 269
+ ++ K L M R ++ S+ + + K + K K + + E + +++ + E +
Sbjct: 630 VNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPE-----EHEQVKSRLEQK 684
Query: 270 SGEEDKKI------NESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQ 323
SGE KKI N++ E + + L +Q + T++++ +V ++ +
Sbjct: 685 SGELGKKITELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSH 744
Query: 324 ALILESLNTNLY-----YTQLELQKEKAIVGN--LEK---MLQTKFAETEEKYKHTIQIL 373
I++ LN L YT+ +L+ EK ++ N L K L+T F E+ K I +
Sbjct: 745 DAIIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIAL- 803
Query: 374 TEENIHLKQKIISKNEEICEGCSGRLASIT 403
+ NI +K +S+ ++ C ++ ++T
Sbjct: 804 -KSNIVELKKQLSELKKKCGEDQEKIHALT 832
Score = 52.0 bits (123), Expect = 1e-06
Identities = 85/425 (20%), Positives = 170/425 (40%), Gaps = 100/425 (23%)
Query: 64 KIHSARQEETNKSFYEVINVSPGYQLVRNREQISVTLGD-------EMFDRKKRWES--- 113
KIH+ E TN +S Y V+ E++ +TL D E+ D KK++E
Sbjct: 827 KIHALTSENTNLKKM----MSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQ 882
Query: 114 ---EIPDKGRFSRTNIIS----------DLEEQISELTAIIEQMNRDHQSAQKLLSS--- 157
+I DK + N+ + L E ++++++ + M + S ++L++
Sbjct: 883 EFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRK 942
Query: 158 -----------------EMDL--RCAEMKQ----NFENKNRELKEAHEA---ELSELENN 191
E+D C ++K +FE R+ K + +LSE
Sbjct: 943 GQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQK 1002
Query: 192 YKAALKAEKLAAQE----------------------------------KLEEMGKEYKYL 217
Y + + K QE K +E+ K+ K L
Sbjct: 1003 YSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDL 1062
Query: 218 KNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKF-ERENILLQQKKKMTKKFE--MESGEED 274
+ T ++ +++ E+ +KQ ++ + +++++ L+Q + + K +E+ +E+
Sbjct: 1063 SQKY-TEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEE 1121
Query: 275 KKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNL 334
K + C + + + +LL+ ++ ++ L E + KE ++E+ L
Sbjct: 1122 LKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEES 1181
Query: 335 YYTQLELQKEKAIVGNLE---KMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKN--- 388
E+ K ++ V N + K L+T+ KYK T L + L +K+ + N
Sbjct: 1182 QNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKY 1241
Query: 389 EEICE 393
EE+CE
Sbjct: 1242 EEVCE 1246
Score = 45.1 bits (105), Expect = 1e-04
Identities = 90/419 (21%), Positives = 172/419 (41%), Gaps = 78/419 (18%)
Query: 36 SSKLTPLVPAPKNHNYLQPTKPVVSPKMKIHSARQEETNKSFYEVINVSPGYQLVRNREQ 95
S+KL +PA K N V+ K K + E KS E+ QL R E
Sbjct: 607 SAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEI------RQLKRELEN 660
Query: 96 ISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSA---Q 152
+ L + + E K R + + +L ++I+ELT + + ++ +
Sbjct: 661 VKAKLAQHV-----KPEEHEQVKSRLEQKS--GELGKKITELTLKNQTLQKEIEKVYLDN 713
Query: 153 KLLSSEMDLRCAEMKQNFE--NKNRELKEAHEAELSELENNYKAALK--AEKLAAQEKL- 207
KLL + EMK ++ + ++K++H+A + +L + EK EKL
Sbjct: 714 KLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKLEMEKLL 773
Query: 208 ---EEMGKEYKYLKNMF---RTYQDSIYD------EMEEKWSKQKAKWKKDEK----FER 251
+ + K+ L+ +F ++ I E++++ S+ K K +D++
Sbjct: 774 LENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTS 833
Query: 252 ENILLQQKKKMTKKF-EMESGEEDK--------KINESCSAVFENF---------IQEKE 293
EN L KK M+ ++ +++ EE K K N V + F I++K
Sbjct: 834 ENTNL--KKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKN 891
Query: 294 ELLKQHQSDT--------LQLEE----LRKTKEVMQEELHAQALILESLNTN---LYYTQ 338
E+LK++ +T + L E + + M++ + A IL + +
Sbjct: 892 EILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLH 951
Query: 339 LELQKEKAIVGNLEKMLQTKFA------ETEEKYKHTIQILTEENIHLKQKIISKNEEI 391
E++ +K + +++ ++ K+A E E K+K T + L ++ QK EE+
Sbjct: 952 AEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEV 1010
Score = 35.4 bits (80), Expect = 0.098
Identities = 45/255 (17%), Positives = 105/255 (41%), Gaps = 35/255 (13%)
Query: 112 ESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSE------MDLRCAE 165
E +P + +S I L++++ + E +D Q L+ + + L C
Sbjct: 414 ELSLPSQTSYSENEI---LKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECER 470
Query: 166 MKQNFENKNRELKEA----------HEAELSELENNY---KAALKAEKLAAQEKL-EEMG 211
+K++ + + ++L++A E ++ +++ ++ K L +E + +L EE+
Sbjct: 471 VKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTEELK 530
Query: 212 KEYKYLKNMFRTYQDSI---------YDEMEEKWSKQKAKWKKDEKFERENILL---QQK 259
+ K LK + + + + E++ + + K ++ K ++ + + +++
Sbjct: 531 DQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMERE 590
Query: 260 KKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEE 319
KK K EME ++ + S E F K L + +L E+ + E E
Sbjct: 591 KKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSE 650
Query: 320 LHAQALILESLNTNL 334
+ LE++ L
Sbjct: 651 IRQLKRELENVKAKL 665
Score = 30.4 bits (67), Expect = 3.2
Identities = 31/178 (17%), Positives = 71/178 (39%), Gaps = 20/178 (11%)
Query: 108 KKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSA--QKLLSSEMDLRCAE 165
KK E+ D ++ T SDLE QIS L + +NR ++ + L + + ++ +
Sbjct: 1203 KKLETREVVDLSKYKATK--SDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAKD 1260
Query: 166 MKQ----NFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMF 221
K+ + E + ++ KE + L+ + Q +++E K+ + N
Sbjct: 1261 EKELLHFSIEQEIKDQKERCDKSLTTITE------------LQRRIQESAKQIEAKDNKI 1308
Query: 222 RTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINE 279
+ + + + + +R++ L+ + K E + + D++ E
Sbjct: 1309 TELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQE 1366
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 59.3 bits (142), Expect = 6e-09
Identities = 75/330 (22%), Positives = 148/330 (44%), Gaps = 42/330 (12%)
Query: 95 QISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSA--- 151
+++ L D++ D K ++E + G+ L QI + I+E+ RD
Sbjct: 537 RLTEELKDQLKDLKVKYEGASAEVGK---------LRNQIKQNEMIVEEFKRDEGKLIEE 587
Query: 152 QKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKL--EE 209
K L E+ + EM++ E K R++ E E + EL ++ AEK + E
Sbjct: 588 NKRLQKELSM--CEMER--EKKGRKVTEM-EGQAKELSAKLALSIPAEKFENMKSSLSNE 642
Query: 210 MGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEME 269
+ ++ K L M R ++ S+ + + K + K K + + E + +++ + E +
Sbjct: 643 VNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPE-----EHEQVKSRLEQK 697
Query: 270 SGEEDKKI------NESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQ 323
SGE KKI N++ E + + L +Q + T++++ +V ++ +
Sbjct: 698 SGELGKKITELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSH 757
Query: 324 ALILESLNTNLY-----YTQLELQKEKAIVGN--LEK---MLQTKFAETEEKYKHTIQIL 373
I++ LN L YT+ +L+ EK ++ N L K L+T F E+ K I +
Sbjct: 758 DAIIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIAL- 816
Query: 374 TEENIHLKQKIISKNEEICEGCSGRLASIT 403
+ NI +K +S+ ++ C ++ ++T
Sbjct: 817 -KSNIVELKKQLSELKKKCGEDQEKIHALT 845
Score = 52.0 bits (123), Expect = 1e-06
Identities = 85/425 (20%), Positives = 170/425 (40%), Gaps = 100/425 (23%)
Query: 64 KIHSARQEETNKSFYEVINVSPGYQLVRNREQISVTLGD-------EMFDRKKRWES--- 113
KIH+ E TN +S Y V+ E++ +TL D E+ D KK++E
Sbjct: 840 KIHALTSENTNLKKM----MSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQ 895
Query: 114 ---EIPDKGRFSRTNIIS----------DLEEQISELTAIIEQMNRDHQSAQKLLSS--- 157
+I DK + N+ + L E ++++++ + M + S ++L++
Sbjct: 896 EFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRK 955
Query: 158 -----------------EMDL--RCAEMKQ----NFENKNRELKEAHEA---ELSELENN 191
E+D C ++K +FE R+ K + +LSE
Sbjct: 956 GQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQK 1015
Query: 192 YKAALKAEKLAAQE----------------------------------KLEEMGKEYKYL 217
Y + + K QE K +E+ K+ K L
Sbjct: 1016 YSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDL 1075
Query: 218 KNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKF-ERENILLQQKKKMTKKFE--MESGEED 274
+ T ++ +++ E+ +KQ ++ + +++++ L+Q + + K +E+ +E+
Sbjct: 1076 SQKY-TEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEE 1134
Query: 275 KKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNL 334
K + C + + + +LL+ ++ ++ L E + KE ++E+ L
Sbjct: 1135 LKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEES 1194
Query: 335 YYTQLELQKEKAIVGNLE---KMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKN--- 388
E+ K ++ V N + K L+T+ KYK T L + L +K+ + N
Sbjct: 1195 QNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKY 1254
Query: 389 EEICE 393
EE+CE
Sbjct: 1255 EEVCE 1259
Score = 45.1 bits (105), Expect = 1e-04
Identities = 90/419 (21%), Positives = 172/419 (41%), Gaps = 78/419 (18%)
Query: 36 SSKLTPLVPAPKNHNYLQPTKPVVSPKMKIHSARQEETNKSFYEVINVSPGYQLVRNREQ 95
S+KL +PA K N V+ K K + E KS E+ QL R E
Sbjct: 620 SAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEI------RQLKRELEN 673
Query: 96 ISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSA---Q 152
+ L + + E K R + + +L ++I+ELT + + ++ +
Sbjct: 674 VKAKLAQHV-----KPEEHEQVKSRLEQKS--GELGKKITELTLKNQTLQKEIEKVYLDN 726
Query: 153 KLLSSEMDLRCAEMKQNFE--NKNRELKEAHEAELSELENNYKAALK--AEKLAAQEKL- 207
KLL + EMK ++ + ++K++H+A + +L + EK EKL
Sbjct: 727 KLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKLEMEKLL 786
Query: 208 ---EEMGKEYKYLKNMF---RTYQDSIYD------EMEEKWSKQKAKWKKDEK----FER 251
+ + K+ L+ +F ++ I E++++ S+ K K +D++
Sbjct: 787 LENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTS 846
Query: 252 ENILLQQKKKMTKKF-EMESGEEDK--------KINESCSAVFENF---------IQEKE 293
EN L KK M+ ++ +++ EE K K N V + F I++K
Sbjct: 847 ENTNL--KKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKN 904
Query: 294 ELLKQHQSDT--------LQLEE----LRKTKEVMQEELHAQALILESLNTN---LYYTQ 338
E+LK++ +T + L E + + M++ + A IL + +
Sbjct: 905 EILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLH 964
Query: 339 LELQKEKAIVGNLEKMLQTKFA------ETEEKYKHTIQILTEENIHLKQKIISKNEEI 391
E++ +K + +++ ++ K+A E E K+K T + L ++ QK EE+
Sbjct: 965 AEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEV 1023
Score = 35.4 bits (80), Expect = 0.098
Identities = 45/255 (17%), Positives = 105/255 (41%), Gaps = 35/255 (13%)
Query: 112 ESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSE------MDLRCAE 165
E +P + +S I L++++ + E +D Q L+ + + L C
Sbjct: 427 ELSLPSQTSYSENEI---LKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECER 483
Query: 166 MKQNFENKNRELKEA----------HEAELSELENNY---KAALKAEKLAAQEKL-EEMG 211
+K++ + + ++L++A E ++ +++ ++ K L +E + +L EE+
Sbjct: 484 VKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTEELK 543
Query: 212 KEYKYLKNMFRTYQDSI---------YDEMEEKWSKQKAKWKKDEKFERENILL---QQK 259
+ K LK + + + + E++ + + K ++ K ++ + + +++
Sbjct: 544 DQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMERE 603
Query: 260 KKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEE 319
KK K EME ++ + S E F K L + +L E+ + E E
Sbjct: 604 KKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSE 663
Query: 320 LHAQALILESLNTNL 334
+ LE++ L
Sbjct: 664 IRQLKRELENVKAKL 678
Score = 30.4 bits (67), Expect = 3.2
Identities = 31/178 (17%), Positives = 71/178 (39%), Gaps = 20/178 (11%)
Query: 108 KKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSA--QKLLSSEMDLRCAE 165
KK E+ D ++ T SDLE QIS L + +NR ++ + L + + ++ +
Sbjct: 1216 KKLETREVVDLSKYKATK--SDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAKD 1273
Query: 166 MKQ----NFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMF 221
K+ + E + ++ KE + L+ + Q +++E K+ + N
Sbjct: 1274 EKELLHFSIEQEIKDQKERCDKSLTTITE------------LQRRIQESAKQIEAKDNKI 1321
Query: 222 RTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINE 279
+ + + + + +R++ L+ + K E + + D++ E
Sbjct: 1322 TELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQE 1379
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 59.3 bits (142), Expect = 6e-09
Identities = 83/373 (22%), Positives = 154/373 (41%), Gaps = 53/373 (14%)
Query: 72 ETNKSFYEVINVSPG-YQLVRNREQISVTLGDEMFDRKKRWES----------EIPDKGR 120
ET + +E + + +R+R + T G+E+ ++K++ E K
Sbjct: 368 ETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTE 427
Query: 121 FSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEA 180
+R + ++++EQI + E+ + S Q+ LS MK++ E + +L++
Sbjct: 428 EARRKLKAEMDEQIKTIEKTSEE---ERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKL 484
Query: 181 HEAELSELENNYKAALKAEKLAAQEK----LEEMGKEYKYLKNMFRTYQDSIYDEME--- 233
HE EL+ E L+ + QE+ LE+ EY + + +E+E
Sbjct: 485 HEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQK 544
Query: 234 -----EKWSK-----QKAKWKKDEKFERENIL---LQQKKKMTKKFEMESGEEDKKINES 280
E +K Q+A+ + E E+ L LQ+ K +K + E K N+
Sbjct: 545 KAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKE 604
Query: 281 CSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLE 340
+ + E E E L +HQ D L E+L+ K+ Q E +E L +
Sbjct: 605 ITVMVEKHKTELESL--KHQQDALWTEKLQVLKQQYQTE-------MEKLREKCEQEKET 655
Query: 341 LQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEICEGCSGRLA 400
L K+K I+ A EE + T++ L + L + + S+ E+ +
Sbjct: 656 LLKDKEIIFQ---------AHIEEMNEKTLEKLDVKQTEL-ESLSSELSEVLKARHKLEE 705
Query: 401 SITVSKDDSDTVQ 413
++V KD +D ++
Sbjct: 706 ELSVLKDQTDKMK 718
Score = 56.2 bits (134), Expect = 5e-08
Identities = 62/277 (22%), Positives = 128/277 (46%), Gaps = 36/277 (12%)
Query: 130 LEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSE-- 187
LE++I EL + + + H+ + L+S+ + A + + NK EL E + E S+
Sbjct: 1852 LEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSH 1911
Query: 188 -----LENNYKAA---LKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQ 239
L +N +A L+ + A+ + +++GKE L+ R + E+E K+
Sbjct: 1912 LVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEIL--KK 1969
Query: 240 KAKWKKDEKFERENILLQQK-----KKMTKKFEMESGEEDKKINESCSAVFENFIQEKEE 294
+ +++EK ++E L+ K K++ ++F + ++++++ + + + E
Sbjct: 1970 EYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAE 2029
Query: 295 LLKQHQSDTLQL--------EELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKA 346
LL+ HQ +T QL ++L++T + +E L A+ E + + Q +L++
Sbjct: 2030 LLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDARE---EEMTAKVRDLQTQLEE--- 2083
Query: 347 IVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQK 383
L+K Q K + E + I+ E L QK
Sbjct: 2084 ----LQKKYQQKLEQEENPGNDNVTIM-ELQTQLAQK 2115
Score = 52.8 bits (125), Expect = 6e-07
Identities = 59/304 (19%), Positives = 132/304 (43%), Gaps = 21/304 (6%)
Query: 89 LVRNREQISVTLGDEMFDRKKRWESEIPDKGRF-----SRTNIISDLEEQISELTAIIEQ 143
L +E + L + + + +K + + +K + N+I LE+ + A ++
Sbjct: 312 LTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKR 371
Query: 144 MNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAA 203
+ ++ +++ R +M E + +++ A ELE A K E+ A
Sbjct: 372 QMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEE--A 429
Query: 204 QEKLE-EMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKM 262
+ KL+ EM ++ K ++ + S+ E+ + KK + +Q K+
Sbjct: 430 RRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSE--------EQIAKL 481
Query: 263 TKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVM---QEE 319
K E E +++++ + F ++ + L++ QS+ L++ + ++ +E + + E
Sbjct: 482 QKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELE 541
Query: 320 LHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAETEEKYKH-TIQILTEENI 378
L +A++ ES N L Q E + + + LE L+ E + + K + + E+N
Sbjct: 542 LQKKAILTESEN-KLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNK 600
Query: 379 HLKQ 382
H K+
Sbjct: 601 HNKE 604
Score = 52.0 bits (123), Expect = 1e-06
Identities = 52/238 (21%), Positives = 101/238 (42%), Gaps = 25/238 (10%)
Query: 100 LGDEMFDRKKRWESEIP--DKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSS 157
LG+E +R K E +I + +S + ++++ + ++ + ++ + L S
Sbjct: 1572 LGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLES 1631
Query: 158 EMDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYL 217
E + AE+K+ E K +K+ +++ E E YK ++ KL+E +E L
Sbjct: 1632 ESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHIL 1691
Query: 218 KNMFRTYQDS---------------IYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKM 262
+ ++ + S Y E EE S+ + +EK L +K+K+
Sbjct: 1692 EEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKL 1751
Query: 263 TKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEEL 320
++ E E+ S+ FE Q +E L+K ++ Q E+ +QEEL
Sbjct: 1752 LQRVGQEK-------EETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGH-LQEEL 1801
Score = 50.4 bits (119), Expect = 3e-06
Identities = 59/267 (22%), Positives = 120/267 (44%), Gaps = 25/267 (9%)
Query: 129 DLEEQ---ISELTAIIEQMNRD---HQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHE 182
DLE + +++ A +E +D A K+ ++ + + E K + L + +E
Sbjct: 830 DLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYE 889
Query: 183 AELS----ELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSK 238
++L E E + ++ E + Q + E KE + L +DSI+ EE +K
Sbjct: 890 SKLEDGNKEQEQTKQILVEKENMILQMR-EGQKKEIEILTQKLSAKEDSIHILNEEYETK 948
Query: 239 QKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQ 298
K + KK EK +++ +Q+ K KK + + K++ + + + Q ++L+
Sbjct: 949 FKNQEKKMEKVKQKAKEMQETLK--KKLLDQEAKLKKELENTALELSQKEKQFNAKMLEM 1006
Query: 299 HQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTK 358
Q+++ + + E Q+E +ESL T++ ++ ++ EK L +
Sbjct: 1007 AQANSAGISDAVSRLETNQKEQ------IESL------TEVHRRELNDVISIWEKKLNQQ 1054
Query: 359 FAETEEKYKHTIQILTEENIHLKQKII 385
E +E ++ +Q +E LKQKI+
Sbjct: 1055 AEELQEIHEIQLQEKEQEVAELKQKIL 1081
Score = 50.4 bits (119), Expect = 3e-06
Identities = 69/303 (22%), Positives = 124/303 (40%), Gaps = 32/303 (10%)
Query: 127 ISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELS 186
IS L +Q E + +D LS E + E ++ NK E K+ ++ +
Sbjct: 1396 ISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEK-ISALEQVDDWSNKFSEWKKKAQSRFT 1454
Query: 187 ELENNYKAA---LKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKW 243
+ +N K L+ + A EK E++ + L + + D + EME+ SK + K
Sbjct: 1455 QHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRF-DCLKGEMEDDKSKMEKK- 1512
Query: 244 KKDEKFERENILLQQKKKMTKKFEMESGEEDKKIN-ESCSAVFENFIQEKEELLKQHQSD 302
N+ + K + + E+E K I ES + V +N+ Q+K+ K+
Sbjct: 1513 -------ESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQK 1565
Query: 303 TLQLEELRKTKEVMQEELHAQALILE----SLNTNLYYTQLELQ--------KE---KAI 347
+EL + K+ +E + L LE S+ L + EL+ KE KA+
Sbjct: 1566 LQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKAL 1625
Query: 348 VGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEICEGCSGRLASITVSKD 407
LE K AE + K + I + ++ L ++ K E+ +G L+ +
Sbjct: 1626 EDRLESESAAKLAELKRKAEQKIAAIKKQ---LLSQMEEKEEQYKKGTESHLSELNTKLQ 1682
Query: 408 DSD 410
+ +
Sbjct: 1683 ERE 1685
Score = 46.6 bits (109), Expect = 4e-05
Identities = 65/363 (17%), Positives = 154/363 (42%), Gaps = 56/363 (15%)
Query: 53 QPTKPVVSPKMKIHSARQEETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWE 112
Q + ++ K I A EE N+ E ++V E +S L + + R K E
Sbjct: 651 QEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQ-----TELESLSSELSEVLKARHKLEE 705
Query: 113 --SEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNF 170
S + D+ + + + ++EQ + ++ + ++H+ + + + + +++
Sbjct: 706 ELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLL 765
Query: 171 ENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYD 230
+ +++ LKE H+A + LE + K + + E A KL+ +F++YQ + ++
Sbjct: 766 KERDKHLKE-HQAHVENLEADIKRS-EGELQQASAKLD-----------VFQSYQSATHE 812
Query: 231 EMEEKWSKQKAKWKKDEKFERENILLQ----------------------QKKKMTKKFEM 268
+ + + +K E E ILL Q + + ++ E
Sbjct: 813 QTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEK 872
Query: 269 ESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILE 328
++ E ++K+ +S + V+E+ +++ + E +TK+++ E+ + + E
Sbjct: 873 QNSEMEQKV-KSLTQVYESKLEDGNK-------------EQEQTKQILVEKENMILQMRE 918
Query: 329 SLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKN 388
+ +L ++ + L + +TKF E+K + Q E LK+K++ +
Sbjct: 919 GQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQE 978
Query: 389 EEI 391
++
Sbjct: 979 AKL 981
Score = 44.3 bits (103), Expect = 2e-04
Identities = 65/364 (17%), Positives = 150/364 (41%), Gaps = 53/364 (14%)
Query: 70 QEETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISD 129
Q+E ++ EV++V + ++ E+ L R E E+ K +
Sbjct: 456 QQELSRVKQEVVDV-----MKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQ 510
Query: 130 LEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELK---EAHEAELS 186
++ + + + +++++ + + L E++L+ + ENK R+L+ E + +
Sbjct: 511 MKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRIL 570
Query: 187 ELENNYKAALK--------------AEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDE- 231
ELE++ + +L+ AEK +++ M +++K + QD+++ E
Sbjct: 571 ELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEK 630
Query: 232 --------------MEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKI 277
+ EK ++K KD++ + + + +K +K +++ E
Sbjct: 631 LQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTE----- 685
Query: 278 NESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYT 337
E+ E E+LK +L L+ + M++EL A+ + E N +
Sbjct: 686 -------LESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAK--MDEQKNHHQQQV 736
Query: 338 QLELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLK--QKIISKNEEICEGC 395
+++ + + EK L+ + + E K + L E H++ + I ++E +
Sbjct: 737 DSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQA 796
Query: 396 SGRL 399
S +L
Sbjct: 797 SAKL 800
Score = 40.4 bits (93), Expect = 0.003
Identities = 60/314 (19%), Positives = 126/314 (40%), Gaps = 31/314 (9%)
Query: 102 DEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDL 161
+++ + K + + K + +LE EL+ +Q N + S+ +
Sbjct: 957 EKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISD 1016
Query: 162 RCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQE----KLEEMGKEYKYL 217
+ ++ N + + L E H EL+++ + ++ L + QE +L+E +E L
Sbjct: 1017 AVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAEL 1076
Query: 218 KNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENIL--LQQKKKMTKKFEMESGEEDK 275
K Q + E++ ++ W K+E +++ L LQ++ K +++
Sbjct: 1077 K------QKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDET 1130
Query: 276 KINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLY 335
K+ + + +L K + +T E+L + K + +E+ + L + L
Sbjct: 1131 KLKAHLEKL-------EVDLNKSLKENTFLQEQLVELKMLAEEDKRK----VSELTSKLK 1179
Query: 336 YTQLELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEICEGC 395
T E Q K+ K L+ K E ++ L+EE K E + E
Sbjct: 1180 TTDEEFQSLKSSHEKSNKSLEDKSLEFKK--------LSEELAIQLDICCKKTEALLEAK 1231
Query: 396 SGRLASITVSKDDS 409
+ L +I+ SK ++
Sbjct: 1232 TNELINISSSKTNA 1245
Score = 33.1 bits (74), Expect = 0.49
Identities = 59/254 (23%), Positives = 99/254 (38%), Gaps = 33/254 (12%)
Query: 123 RTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHE 182
+T +S+LE Q+ +LT +N Q A L E + + MK + E+ L E
Sbjct: 1267 KTCTVSELEAQLRQLTEEQNTLNISFQQATHQLE-EKENQIKSMKADIES----LVTEKE 1321
Query: 183 AELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAK 242
A E N +AA + E Q K KE N ++ + ++ E S K
Sbjct: 1322 ALQKEGGNQQQAASEKESCITQLK-----KELSENINAVTLMKEELKEKKVEISSLSK-- 1374
Query: 243 WKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSD 302
+ N+ LQ +++K + S++ + + +EK ELL Q Q
Sbjct: 1375 -----QLTDLNVQLQNSISLSEK------------EAAISSLRKQYDEEKCELLDQVQDL 1417
Query: 303 TLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAET 362
+ +++ L K K E++ + Q + + V L+ L+ K E
Sbjct: 1418 SFKVDTLSKEKISALEQVDDWSNKFSEWKKK---AQSRFTQHQNTVKELQIQLELKSKEA 1474
Query: 363 EEKYKHTIQILTEE 376
EK I +L EE
Sbjct: 1475 YEK-DEQINLLKEE 1487
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 58.9 bits (141), Expect = 8e-09
Identities = 51/240 (21%), Positives = 111/240 (46%), Gaps = 20/240 (8%)
Query: 107 RKKRWESEIPDKGRFSRTNII---SDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRC 163
+K+R + E ++ R ++ + L+E+ +E + + A++LL E + R
Sbjct: 327 QKRREQREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEAQRQAERLLQEEEERR- 385
Query: 164 AEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRT 223
+++REL++A E +L E E +A+++AE +E+ + K L+ M +
Sbjct: 386 -------RSQHRELQQALEGQLREAEQA-RASMQAEMELKEEEAARQRQRIKELEEMQQR 437
Query: 224 YQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSA 283
Q+++ E++ + ++ + + E E L+Q M+ EE ++ E
Sbjct: 438 LQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQL--------MQLKEEQERYIERAQQ 489
Query: 284 VFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQK 343
E QE + + Q QLEE+R+ ++ E++ A L +TN+ + +++ +
Sbjct: 490 EKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQASTNVKHWNVQMNR 549
Score = 37.7 bits (86), Expect = 0.020
Identities = 45/228 (19%), Positives = 102/228 (44%), Gaps = 18/228 (7%)
Query: 196 LKAE-KLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENI 254
L+AE K + + L++ +E + + R ++ EE Q+ + +K+ K + E
Sbjct: 313 LQAEGKTSLHKDLKQKRREQREQRERRRAAKE------EELLRLQQLQEEKERKLQ-ELE 365
Query: 255 LLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSD-TLQLEELRKTK 313
LLQ+ ++ ++ E E + + E ++E E+ Q++ L+ EE + +
Sbjct: 366 LLQEAQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAEMELKEEEAARQR 425
Query: 314 EVMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQIL 373
+ ++E Q + E+L QLE++ + ++ QT+ E EE+ + L
Sbjct: 426 QRIKELEEMQQRLQEAL-------QLEVKARRD--EESVRIAQTRLLEEEEEKLKQLMQL 476
Query: 374 TEENIHLKQKIISKNEEICEGCSGRLASITVSKDDSDTVQDGSKKGQE 421
EE ++ + EE+ + + + S+ ++ + V+ ++ E
Sbjct: 477 KEEQERYIERAQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADE 524
>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
Length = 495
Score = 58.9 bits (141), Expect = 8e-09
Identities = 66/276 (23%), Positives = 120/276 (43%), Gaps = 40/276 (14%)
Query: 133 QISELTAI-IEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELENN 191
QI+E AI EQM RD + A+ ++ E R + + E+K + K + +L +
Sbjct: 140 QIAEKDAIKYEQMKRDAEIAKTMM--EEHKRIIKEENAAEDKRNKAKAQYYLDLEK---- 193
Query: 192 YKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFER 251
L+ ++ QE E++ KE + + R + E ++K K A + E+F++
Sbjct: 194 ---QLEEQEKKKQEAYEQLLKEKLMIDEIVRKIYEEDQLEKQQKLEKMNAMRRYIEEFQK 250
Query: 252 ENILLQQKKKMTKKFE----------MESGEEDK----KINESCSAVFENFIQEK-EELL 296
E L ++KK+ + E + EED+ + NE +N + +K EE+L
Sbjct: 251 EQALWRKKKREEMEEENRKIIEFANMQQQREEDRMAKVQENEEKRLQLQNALTQKLEEML 310
Query: 297 KQHQSDTLQLEEL----------RKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKA 346
+Q + +EL K KE +++L Q + + + +L LQ K
Sbjct: 311 RQREDLEQVRQELYQEEQAEIYKSKLKEEAEKKLRKQKEMKQDFEEQMALKELVLQAAKE 370
Query: 347 IVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQ 382
N K + KFAE + I+++ + +KQ
Sbjct: 371 EEENFRKTMLAKFAEDDR-----IELMNAQKQRMKQ 401
Score = 53.5 bits (127), Expect = 3e-07
Identities = 66/254 (25%), Positives = 116/254 (45%), Gaps = 34/254 (13%)
Query: 129 DLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNF--ENKNRELKEAHEAELS 186
D+EE I + + N+ + Q ++ + A++K + K R+ + EL
Sbjct: 68 DMEEAIQKA-----EENKRLKELQLKQEEKLAMELAKLKHESLKDEKMRQQVRENSIELR 122
Query: 187 ELENNYKAALKAEKLAAQ------EKLEEMGKEYKYLKNMFRTYQDSIYDE--MEEKWSK 238
ELE KAA ++ AAQ K E+M ++ + K M ++ I +E E+K +K
Sbjct: 123 ELEKKLKAAYMNKERAAQIAEKDAIKYEQMKRDAEIAKTMMEEHKRIIKEENAAEDKRNK 182
Query: 239 QKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQ 298
KA++ D E L +Q+KK + +E + +E I+E ++E EK++ L++
Sbjct: 183 AKAQYYLD----LEKQLEEQEKKKQEAYE-QLLKEKLMIDEIVRKIYEEDQLEKQQKLEK 237
Query: 299 HQSDTLQLEEL--------RKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKAIVGN 350
+ +EE +K +E M+EE I+E N Q E + + N
Sbjct: 238 MNAMRRYIEEFQKEQALWRKKKREEMEEE---NRKIIEFANMQ---QQREEDRMAKVQEN 291
Query: 351 LEKMLQTKFAETEE 364
EK LQ + A T++
Sbjct: 292 EEKRLQLQNALTQK 305
Score = 43.5 bits (101), Expect = 4e-04
Identities = 61/292 (20%), Positives = 122/292 (41%), Gaps = 54/292 (18%)
Query: 104 MFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRC 163
++ +KKR E E ++ N+ EE + A +++ Q L+ +++
Sbjct: 254 LWRKKKREEMEEENRKIIEFANMQQQREE---DRMAKVQENEEKRLQLQNALTQKLE-EM 309
Query: 164 AEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRT 223
+++ E +EL + +AE+ YK+ LK E K +EM ++++ +
Sbjct: 310 LRQREDLEQVRQELYQEEQAEI------YKSKLKEEAEKKLRKQKEMKQDFEEQMALKEL 363
Query: 224 YQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSA 283
+ +E E AK+ +D++ E N Q+ K++ + +E E+++
Sbjct: 364 VLQAAKEEEENFRKTMLAKFAEDDRIELMNAQKQRMKQLEHRRAVEKLIEERR------- 416
Query: 284 VFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQK 343
+ F+ +K+ L++ Q LQ +++EE +L+L K
Sbjct: 417 --QQFLADKQRELEEWQ---LQQRRQGFINAIIEEE------------------RLKLLK 453
Query: 344 EKA--IVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEICE 393
E A ++G L K + K + I +L EE +K+ + EICE
Sbjct: 454 EHATNLLGYLPKGVFKK--------EDDIDLLGEE----FRKVYQQRSEICE 493
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 58.5 bits (140), Expect = 1e-08
Identities = 77/349 (22%), Positives = 152/349 (43%), Gaps = 50/349 (14%)
Query: 64 KIHSARQEETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIPDKGRFSR 123
K+H + E +S ++N + G + ++ S L ++ D ++ + E K
Sbjct: 1281 KVHKLQNEV--ESVTGMLNEAEGKAIKLAKDVAS--LSSQLQDTQELLQEETRQK----- 1331
Query: 124 TNIISDLEEQISELTAIIEQMNRDHQSAQKLLS--SEMDLRCAEMK---QNFENKNRELK 178
N+ + L + E ++ +Q++ + ++ Q L S ++++ ++ K Q+F + L+
Sbjct: 1332 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1391
Query: 179 EAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSK 238
E + E+EN + EK AA +KLE+ KN + D + +++ +
Sbjct: 1392 EGKKRFQKEIENLTQQY--EEKAAAYDKLEKT-------KNRLQQELDDLVVDLDNQRQL 1442
Query: 239 QKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINE------SCSAVFENFIQEK 292
KK KF++ LL ++K ++ K+ E + + E S + E ++ K
Sbjct: 1443 VSNLEKKQRKFDQ---LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAK 1499
Query: 293 EEL------LKQHQSDTL--------QLEELRKTKEVMQEELHAQALILESLNTNLYYTQ 338
EEL LK D + + EL K+K ++ ++ LE L L T+
Sbjct: 1500 EELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE 1559
Query: 339 ---LELQ-KEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQK 383
L L+ +A+ G E+ LQ + + EEK + + L E L+ +
Sbjct: 1560 DAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDE 1608
Score = 53.5 bits (127), Expect = 3e-07
Identities = 84/378 (22%), Positives = 159/378 (42%), Gaps = 78/378 (20%)
Query: 88 QLVRNREQISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRD 147
Q +R + + VT+ + D + R + R + +L EQ+ + ++++
Sbjct: 1166 QELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKN 1225
Query: 148 HQSAQKL---LSSEMDLRCAEMKQNFENKNRELK-------------EAHEAELSE---- 187
Q+ +K L+ E+ + + KQ E+K ++L+ E AEL++
Sbjct: 1226 KQTLEKENADLAGELRV-LGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHK 1284
Query: 188 LENNYKAAL--------KAEKLA------------AQEKLEEMGKEYKYLKNMFRTYQD- 226
L+N ++ KA KLA QE L+E ++ + R ++
Sbjct: 1285 LQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEE 1344
Query: 227 --SIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFE--MESGEEDKKINESCS 282
S+ D+++E+ +AK + NI L KK + F +E+ EE KK
Sbjct: 1345 RNSLQDQLDEE---MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKK------ 1395
Query: 283 AVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQ 342
F +E E L +Q++ ++L KTK +Q+EL L+++ N + LE +
Sbjct: 1396 ----RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL--DDLVVDLDNQRQLVSNLEKK 1449
Query: 343 KEK--AIVGNLEKMLQTKF------AETEEKYKHT----IQILTEENIHLKQKIISKNEE 390
+ K ++ EK + +K+ AE E + K T + EE + K+++ N+
Sbjct: 1450 QRKFDQLLAE-EKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKM 1508
Query: 391 ICEGCSGRLASITVSKDD 408
+ + + SKDD
Sbjct: 1509 L----KAEMEDLVSSKDD 1522
Score = 52.4 bits (124), Expect = 8e-07
Identities = 43/222 (19%), Positives = 103/222 (46%), Gaps = 32/222 (14%)
Query: 106 DRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAE 165
D K+R E+ I + +LEE+ + A+ +++ + Q A++L + R
Sbjct: 1729 DEKRRLEARI--------AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTA 1780
Query: 166 MK-----QNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNM 220
K Q E +N+EL+ ++L E+E K+ K+ A + K+ ++
Sbjct: 1781 QKNESARQQLERQNKELR----SKLHEMEGAVKSKFKSTIAALEAKIAQL---------- 1826
Query: 221 FRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINES 280
++ + E EK + K+ +KD+K + + ++ ++KM ++++ ++ + + ++ +
Sbjct: 1827 ----EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ- 1881
Query: 281 CSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHA 322
E +E + + + +L+E ++ E M E++A
Sbjct: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA 1923
Score = 48.1 bits (113), Expect = 1e-05
Identities = 60/232 (25%), Positives = 108/232 (46%), Gaps = 41/232 (17%)
Query: 165 EMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTY 224
+ K++ K +E ++ E EL ELE + + L EK QE+L+ + Y + M R
Sbjct: 855 QAKEDELQKTKERQQKAENELKELEQKH-SQLTEEKNLLQEQLQAETELYAEAEEM-RVR 912
Query: 225 QDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAV 284
+ E+EE + +A+ +++E +R L ++KKM + +M EE
Sbjct: 913 LAAKKQELEEILHEMEARLEEEE--DRGQQLQAERKKMAQ--QMLDLEEQL--------- 959
Query: 285 FENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKE 344
E+EE +Q LQLE++ T E ++L + L+++ N +L KE
Sbjct: 960 ------EEEEAARQK----LQLEKV--TAEAKIKKLEDEILVMDDQNN-------KLSKE 1000
Query: 345 KAIVGNLEKMLQTKFAETEEKYKHTIQI-------LTEENIHLKQKIISKNE 389
+ ++ L T AE EEK K+ ++ ++E + LK++ S+ E
Sbjct: 1001 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQE 1052
Score = 45.1 bits (105), Expect = 1e-04
Identities = 73/290 (25%), Positives = 135/290 (46%), Gaps = 47/290 (16%)
Query: 130 LEEQISELTAIIEQMNRDHQSAQKL------LSSEMDLRCAE---MKQNFENKNRELK-- 178
LEE+IS+LT + + ++ KL + SE+++R + +Q E R+L+
Sbjct: 1004 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1063
Query: 179 --EAHE------AELSELENNYKAALKAEKL-AAQEKLE-EMGKEYKYLKNMFRTYQDSI 228
+ HE A+++EL+ + A K E+L AA +L+ E+ ++ LK + R + I
Sbjct: 1064 ASDFHEQIADLQAQIAELK--MQLAKKEEELQAALARLDDEIAQKNNALKKI-RELEGHI 1120
Query: 229 YDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENF 288
D ++E ++A K EK +R+ L ++ + + K E+E + + A E
Sbjct: 1121 SD-LQEDLDSERAARNKAEKQKRD--LGEELEAL--KTELEDTLDSTATQQELRAKREQE 1175
Query: 289 IQE-KEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKA- 346
+ K+ L ++ +S Q++E+R+ EEL Q + NL + L+KE A
Sbjct: 1176 VTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENAD 1235
Query: 347 IVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEICEGCS 396
+ G L + Q K +E H K+K+ ++ +E+ CS
Sbjct: 1236 LAGELRVLGQAK----------------QEVEHKKKKLEAQVQELQSKCS 1269
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 58.5 bits (140), Expect = 1e-08
Identities = 77/349 (22%), Positives = 152/349 (43%), Gaps = 50/349 (14%)
Query: 64 KIHSARQEETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIPDKGRFSR 123
K+H + E +S ++N + G + ++ S L ++ D ++ + E K
Sbjct: 1288 KVHKLQNEV--ESVTGMLNEAEGKAIKLAKDVAS--LSSQLQDTQELLQEETRQK----- 1338
Query: 124 TNIISDLEEQISELTAIIEQMNRDHQSAQKLLS--SEMDLRCAEMK---QNFENKNRELK 178
N+ + L + E ++ +Q++ + ++ Q L S ++++ ++ K Q+F + L+
Sbjct: 1339 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1398
Query: 179 EAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSK 238
E + E+EN + EK AA +KLE+ KN + D + +++ +
Sbjct: 1399 EGKKRFQKEIENLTQQY--EEKAAAYDKLEKT-------KNRLQQELDDLVVDLDNQRQL 1449
Query: 239 QKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINE------SCSAVFENFIQEK 292
KK KF++ LL ++K ++ K+ E + + E S + E ++ K
Sbjct: 1450 VSNLEKKQRKFDQ---LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAK 1506
Query: 293 EEL------LKQHQSDTL--------QLEELRKTKEVMQEELHAQALILESLNTNLYYTQ 338
EEL LK D + + EL K+K ++ ++ LE L L T+
Sbjct: 1507 EELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE 1566
Query: 339 ---LELQ-KEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQK 383
L L+ +A+ G E+ LQ + + EEK + + L E L+ +
Sbjct: 1567 DAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDE 1615
Score = 53.5 bits (127), Expect = 3e-07
Identities = 84/378 (22%), Positives = 159/378 (42%), Gaps = 78/378 (20%)
Query: 88 QLVRNREQISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRD 147
Q +R + + VT+ + D + R + R + +L EQ+ + ++++
Sbjct: 1173 QELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKN 1232
Query: 148 HQSAQKL---LSSEMDLRCAEMKQNFENKNRELK-------------EAHEAELSE---- 187
Q+ +K L+ E+ + + KQ E+K ++L+ E AEL++
Sbjct: 1233 KQTLEKENADLAGELRV-LGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHK 1291
Query: 188 LENNYKAAL--------KAEKLA------------AQEKLEEMGKEYKYLKNMFRTYQD- 226
L+N ++ KA KLA QE L+E ++ + R ++
Sbjct: 1292 LQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEE 1351
Query: 227 --SIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFE--MESGEEDKKINESCS 282
S+ D+++E+ +AK + NI L KK + F +E+ EE KK
Sbjct: 1352 RNSLQDQLDEE---MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKK------ 1402
Query: 283 AVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQ 342
F +E E L +Q++ ++L KTK +Q+EL L+++ N + LE +
Sbjct: 1403 ----RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL--DDLVVDLDNQRQLVSNLEKK 1456
Query: 343 KEK--AIVGNLEKMLQTKF------AETEEKYKHT----IQILTEENIHLKQKIISKNEE 390
+ K ++ EK + +K+ AE E + K T + EE + K+++ N+
Sbjct: 1457 QRKFDQLLAE-EKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKM 1515
Query: 391 ICEGCSGRLASITVSKDD 408
+ + + SKDD
Sbjct: 1516 L----KAEMEDLVSSKDD 1529
Score = 52.4 bits (124), Expect = 8e-07
Identities = 43/222 (19%), Positives = 103/222 (46%), Gaps = 32/222 (14%)
Query: 106 DRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAE 165
D K+R E+ I + +LEE+ + A+ +++ + Q A++L + R
Sbjct: 1736 DEKRRLEARI--------AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTA 1787
Query: 166 MK-----QNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNM 220
K Q E +N+EL+ ++L E+E K+ K+ A + K+ ++
Sbjct: 1788 QKNESARQQLERQNKELR----SKLHEMEGAVKSKFKSTIAALEAKIAQL---------- 1833
Query: 221 FRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINES 280
++ + E EK + K+ +KD+K + + ++ ++KM ++++ ++ + + ++ +
Sbjct: 1834 ----EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ- 1888
Query: 281 CSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHA 322
E +E + + + +L+E ++ E M E++A
Sbjct: 1889 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA 1930
Score = 48.1 bits (113), Expect = 1e-05
Identities = 60/232 (25%), Positives = 108/232 (46%), Gaps = 41/232 (17%)
Query: 165 EMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTY 224
+ K++ K +E ++ E EL ELE + + L EK QE+L+ + Y + M R
Sbjct: 862 QAKEDELQKTKERQQKAENELKELEQKH-SQLTEEKNLLQEQLQAETELYAEAEEM-RVR 919
Query: 225 QDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAV 284
+ E+EE + +A+ +++E +R L ++KKM + +M EE
Sbjct: 920 LAAKKQELEEILHEMEARLEEEE--DRGQQLQAERKKMAQ--QMLDLEEQL--------- 966
Query: 285 FENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKE 344
E+EE +Q LQLE++ T E ++L + L+++ N +L KE
Sbjct: 967 ------EEEEAARQK----LQLEKV--TAEAKIKKLEDEILVMDDQNN-------KLSKE 1007
Query: 345 KAIVGNLEKMLQTKFAETEEKYKHTIQI-------LTEENIHLKQKIISKNE 389
+ ++ L T AE EEK K+ ++ ++E + LK++ S+ E
Sbjct: 1008 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQE 1059
Score = 45.1 bits (105), Expect = 1e-04
Identities = 73/290 (25%), Positives = 135/290 (46%), Gaps = 47/290 (16%)
Query: 130 LEEQISELTAIIEQMNRDHQSAQKL------LSSEMDLRCAE---MKQNFENKNRELK-- 178
LEE+IS+LT + + ++ KL + SE+++R + +Q E R+L+
Sbjct: 1011 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1070
Query: 179 --EAHE------AELSELENNYKAALKAEKL-AAQEKLE-EMGKEYKYLKNMFRTYQDSI 228
+ HE A+++EL+ + A K E+L AA +L+ E+ ++ LK + R + I
Sbjct: 1071 ASDFHEQIADLQAQIAELK--MQLAKKEEELQAALARLDDEIAQKNNALKKI-RELEGHI 1127
Query: 229 YDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENF 288
D ++E ++A K EK +R+ L ++ + + K E+E + + A E
Sbjct: 1128 SD-LQEDLDSERAARNKAEKQKRD--LGEELEAL--KTELEDTLDSTATQQELRAKREQE 1182
Query: 289 IQE-KEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKA- 346
+ K+ L ++ +S Q++E+R+ EEL Q + NL + L+KE A
Sbjct: 1183 VTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENAD 1242
Query: 347 IVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEICEGCS 396
+ G L + Q K +E H K+K+ ++ +E+ CS
Sbjct: 1243 LAGELRVLGQAK----------------QEVEHKKKKLEAQVQELQSKCS 1276
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 58.5 bits (140), Expect = 1e-08
Identities = 77/349 (22%), Positives = 152/349 (43%), Gaps = 50/349 (14%)
Query: 64 KIHSARQEETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIPDKGRFSR 123
K+H + E +S ++N + G + ++ S L ++ D ++ + E K
Sbjct: 1288 KVHKLQNEV--ESVTGMLNEAEGKAIKLAKDVAS--LSSQLQDTQELLQEETRQK----- 1338
Query: 124 TNIISDLEEQISELTAIIEQMNRDHQSAQKLLS--SEMDLRCAEMK---QNFENKNRELK 178
N+ + L + E ++ +Q++ + ++ Q L S ++++ ++ K Q+F + L+
Sbjct: 1339 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1398
Query: 179 EAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSK 238
E + E+EN + EK AA +KLE+ KN + D + +++ +
Sbjct: 1399 EGKKRFQKEIENLTQQY--EEKAAAYDKLEKT-------KNRLQQELDDLVVDLDNQRQL 1449
Query: 239 QKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINE------SCSAVFENFIQEK 292
KK KF++ LL ++K ++ K+ E + + E S + E ++ K
Sbjct: 1450 VSNLEKKQRKFDQ---LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAK 1506
Query: 293 EEL------LKQHQSDTL--------QLEELRKTKEVMQEELHAQALILESLNTNLYYTQ 338
EEL LK D + + EL K+K ++ ++ LE L L T+
Sbjct: 1507 EELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE 1566
Query: 339 ---LELQ-KEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQK 383
L L+ +A+ G E+ LQ + + EEK + + L E L+ +
Sbjct: 1567 DAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDE 1615
Score = 53.5 bits (127), Expect = 3e-07
Identities = 84/378 (22%), Positives = 159/378 (42%), Gaps = 78/378 (20%)
Query: 88 QLVRNREQISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRD 147
Q +R + + VT+ + D + R + R + +L EQ+ + ++++
Sbjct: 1173 QELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKN 1232
Query: 148 HQSAQKL---LSSEMDLRCAEMKQNFENKNRELK-------------EAHEAELSE---- 187
Q+ +K L+ E+ + + KQ E+K ++L+ E AEL++
Sbjct: 1233 KQTLEKENADLAGELRV-LGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHK 1291
Query: 188 LENNYKAAL--------KAEKLA------------AQEKLEEMGKEYKYLKNMFRTYQD- 226
L+N ++ KA KLA QE L+E ++ + R ++
Sbjct: 1292 LQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEE 1351
Query: 227 --SIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFE--MESGEEDKKINESCS 282
S+ D+++E+ +AK + NI L KK + F +E+ EE KK
Sbjct: 1352 RNSLQDQLDEE---MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKK------ 1402
Query: 283 AVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQ 342
F +E E L +Q++ ++L KTK +Q+EL L+++ N + LE +
Sbjct: 1403 ----RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL--DDLVVDLDNQRQLVSNLEKK 1456
Query: 343 KEK--AIVGNLEKMLQTKF------AETEEKYKHT----IQILTEENIHLKQKIISKNEE 390
+ K ++ EK + +K+ AE E + K T + EE + K+++ N+
Sbjct: 1457 QRKFDQLLAE-EKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKM 1515
Query: 391 ICEGCSGRLASITVSKDD 408
+ + + SKDD
Sbjct: 1516 L----KAEMEDLVSSKDD 1529
Score = 52.4 bits (124), Expect = 8e-07
Identities = 43/222 (19%), Positives = 103/222 (46%), Gaps = 32/222 (14%)
Query: 106 DRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAE 165
D K+R E+ I + +LEE+ + A+ +++ + Q A++L + R
Sbjct: 1736 DEKRRLEARI--------AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTA 1787
Query: 166 MK-----QNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNM 220
K Q E +N+EL+ ++L E+E K+ K+ A + K+ ++
Sbjct: 1788 QKNESARQQLERQNKELR----SKLHEMEGAVKSKFKSTIAALEAKIAQL---------- 1833
Query: 221 FRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINES 280
++ + E EK + K+ +KD+K + + ++ ++KM ++++ ++ + + ++ +
Sbjct: 1834 ----EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ- 1888
Query: 281 CSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHA 322
E +E + + + +L+E ++ E M E++A
Sbjct: 1889 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA 1930
Score = 48.1 bits (113), Expect = 1e-05
Identities = 60/232 (25%), Positives = 108/232 (46%), Gaps = 41/232 (17%)
Query: 165 EMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTY 224
+ K++ K +E ++ E EL ELE + + L EK QE+L+ + Y + M R
Sbjct: 862 QAKEDELQKTKERQQKAENELKELEQKH-SQLTEEKNLLQEQLQAETELYAEAEEM-RVR 919
Query: 225 QDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAV 284
+ E+EE + +A+ +++E +R L ++KKM + +M EE
Sbjct: 920 LAAKKQELEEILHEMEARLEEEE--DRGQQLQAERKKMAQ--QMLDLEEQL--------- 966
Query: 285 FENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKE 344
E+EE +Q LQLE++ T E ++L + L+++ N +L KE
Sbjct: 967 ------EEEEAARQK----LQLEKV--TAEAKIKKLEDEILVMDDQNN-------KLSKE 1007
Query: 345 KAIVGNLEKMLQTKFAETEEKYKHTIQI-------LTEENIHLKQKIISKNE 389
+ ++ L T AE EEK K+ ++ ++E + LK++ S+ E
Sbjct: 1008 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQE 1059
Score = 45.1 bits (105), Expect = 1e-04
Identities = 73/290 (25%), Positives = 135/290 (46%), Gaps = 47/290 (16%)
Query: 130 LEEQISELTAIIEQMNRDHQSAQKL------LSSEMDLRCAE---MKQNFENKNRELK-- 178
LEE+IS+LT + + ++ KL + SE+++R + +Q E R+L+
Sbjct: 1011 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1070
Query: 179 --EAHE------AELSELENNYKAALKAEKL-AAQEKLE-EMGKEYKYLKNMFRTYQDSI 228
+ HE A+++EL+ + A K E+L AA +L+ E+ ++ LK + R + I
Sbjct: 1071 ASDFHEQIADLQAQIAELK--MQLAKKEEELQAALARLDDEIAQKNNALKKI-RELEGHI 1127
Query: 229 YDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENF 288
D ++E ++A K EK +R+ L ++ + + K E+E + + A E
Sbjct: 1128 SD-LQEDLDSERAARNKAEKQKRD--LGEELEAL--KTELEDTLDSTATQQELRAKREQE 1182
Query: 289 IQE-KEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKA- 346
+ K+ L ++ +S Q++E+R+ EEL Q + NL + L+KE A
Sbjct: 1183 VTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENAD 1242
Query: 347 IVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEICEGCS 396
+ G L + Q K +E H K+K+ ++ +E+ CS
Sbjct: 1243 LAGELRVLGQAK----------------QEVEHKKKKLEAQVQELQSKCS 1276
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 58.5 bits (140), Expect = 1e-08
Identities = 77/349 (22%), Positives = 152/349 (43%), Gaps = 50/349 (14%)
Query: 64 KIHSARQEETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIPDKGRFSR 123
K+H + E +S ++N + G + ++ S L ++ D ++ + E K
Sbjct: 1281 KVHKLQNEV--ESVTGMLNEAEGKAIKLAKDVAS--LSSQLQDTQELLQEETRQK----- 1331
Query: 124 TNIISDLEEQISELTAIIEQMNRDHQSAQKLLS--SEMDLRCAEMK---QNFENKNRELK 178
N+ + L + E ++ +Q++ + ++ Q L S ++++ ++ K Q+F + L+
Sbjct: 1332 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1391
Query: 179 EAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSK 238
E + E+EN + EK AA +KLE+ KN + D + +++ +
Sbjct: 1392 EGKKRFQKEIENLTQQY--EEKAAAYDKLEKT-------KNRLQQELDDLVVDLDNQRQL 1442
Query: 239 QKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINE------SCSAVFENFIQEK 292
KK KF++ LL ++K ++ K+ E + + E S + E ++ K
Sbjct: 1443 VSNLEKKQRKFDQ---LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAK 1499
Query: 293 EEL------LKQHQSDTL--------QLEELRKTKEVMQEELHAQALILESLNTNLYYTQ 338
EEL LK D + + EL K+K ++ ++ LE L L T+
Sbjct: 1500 EELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE 1559
Query: 339 ---LELQ-KEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQK 383
L L+ +A+ G E+ LQ + + EEK + + L E L+ +
Sbjct: 1560 DAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDE 1608
Score = 53.5 bits (127), Expect = 3e-07
Identities = 84/378 (22%), Positives = 159/378 (42%), Gaps = 78/378 (20%)
Query: 88 QLVRNREQISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRD 147
Q +R + + VT+ + D + R + R + +L EQ+ + ++++
Sbjct: 1166 QELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKN 1225
Query: 148 HQSAQKL---LSSEMDLRCAEMKQNFENKNRELK-------------EAHEAELSE---- 187
Q+ +K L+ E+ + + KQ E+K ++L+ E AEL++
Sbjct: 1226 KQTLEKENADLAGELRV-LGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHK 1284
Query: 188 LENNYKAAL--------KAEKLA------------AQEKLEEMGKEYKYLKNMFRTYQD- 226
L+N ++ KA KLA QE L+E ++ + R ++
Sbjct: 1285 LQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEE 1344
Query: 227 --SIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFE--MESGEEDKKINESCS 282
S+ D+++E+ +AK + NI L KK + F +E+ EE KK
Sbjct: 1345 RNSLQDQLDEE---MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKK------ 1395
Query: 283 AVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQ 342
F +E E L +Q++ ++L KTK +Q+EL L+++ N + LE +
Sbjct: 1396 ----RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL--DDLVVDLDNQRQLVSNLEKK 1449
Query: 343 KEK--AIVGNLEKMLQTKF------AETEEKYKHT----IQILTEENIHLKQKIISKNEE 390
+ K ++ EK + +K+ AE E + K T + EE + K+++ N+
Sbjct: 1450 QRKFDQLLAE-EKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKM 1508
Query: 391 ICEGCSGRLASITVSKDD 408
+ + + SKDD
Sbjct: 1509 L----KAEMEDLVSSKDD 1522
Score = 52.4 bits (124), Expect = 8e-07
Identities = 43/222 (19%), Positives = 103/222 (46%), Gaps = 32/222 (14%)
Query: 106 DRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAE 165
D K+R E+ I + +LEE+ + A+ +++ + Q A++L + R
Sbjct: 1729 DEKRRLEARI--------AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTA 1780
Query: 166 MK-----QNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNM 220
K Q E +N+EL+ ++L E+E K+ K+ A + K+ ++
Sbjct: 1781 QKNESARQQLERQNKELR----SKLHEMEGAVKSKFKSTIAALEAKIAQL---------- 1826
Query: 221 FRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINES 280
++ + E EK + K+ +KD+K + + ++ ++KM ++++ ++ + + ++ +
Sbjct: 1827 ----EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ- 1881
Query: 281 CSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHA 322
E +E + + + +L+E ++ E M E++A
Sbjct: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA 1923
Score = 48.1 bits (113), Expect = 1e-05
Identities = 60/232 (25%), Positives = 108/232 (46%), Gaps = 41/232 (17%)
Query: 165 EMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTY 224
+ K++ K +E ++ E EL ELE + + L EK QE+L+ + Y + M R
Sbjct: 855 QAKEDELQKTKERQQKAENELKELEQKH-SQLTEEKNLLQEQLQAETELYAEAEEM-RVR 912
Query: 225 QDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAV 284
+ E+EE + +A+ +++E +R L ++KKM + +M EE
Sbjct: 913 LAAKKQELEEILHEMEARLEEEE--DRGQQLQAERKKMAQ--QMLDLEEQL--------- 959
Query: 285 FENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKE 344
E+EE +Q LQLE++ T E ++L + L+++ N +L KE
Sbjct: 960 ------EEEEAARQK----LQLEKV--TAEAKIKKLEDEILVMDDQNN-------KLSKE 1000
Query: 345 KAIVGNLEKMLQTKFAETEEKYKHTIQI-------LTEENIHLKQKIISKNE 389
+ ++ L T AE EEK K+ ++ ++E + LK++ S+ E
Sbjct: 1001 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQE 1052
Score = 45.1 bits (105), Expect = 1e-04
Identities = 73/290 (25%), Positives = 135/290 (46%), Gaps = 47/290 (16%)
Query: 130 LEEQISELTAIIEQMNRDHQSAQKL------LSSEMDLRCAE---MKQNFENKNRELK-- 178
LEE+IS+LT + + ++ KL + SE+++R + +Q E R+L+
Sbjct: 1004 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1063
Query: 179 --EAHE------AELSELENNYKAALKAEKL-AAQEKLE-EMGKEYKYLKNMFRTYQDSI 228
+ HE A+++EL+ + A K E+L AA +L+ E+ ++ LK + R + I
Sbjct: 1064 ASDFHEQIADLQAQIAELK--MQLAKKEEELQAALARLDDEIAQKNNALKKI-RELEGHI 1120
Query: 229 YDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENF 288
D ++E ++A K EK +R+ L ++ + + K E+E + + A E
Sbjct: 1121 SD-LQEDLDSERAARNKAEKQKRD--LGEELEAL--KTELEDTLDSTATQQELRAKREQE 1175
Query: 289 IQE-KEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKA- 346
+ K+ L ++ +S Q++E+R+ EEL Q + NL + L+KE A
Sbjct: 1176 VTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENAD 1235
Query: 347 IVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKIISKNEEICEGCS 396
+ G L + Q K +E H K+K+ ++ +E+ CS
Sbjct: 1236 LAGELRVLGQAK----------------QEVEHKKKKLEAQVQELQSKCS 1269
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 58.2 bits (139), Expect = 1e-08
Identities = 70/332 (21%), Positives = 142/332 (42%), Gaps = 26/332 (7%)
Query: 38 KLTPLVPAPKNHNYLQPTKPV---VSPKMKIHSARQEETNKSFYEVINVSPGYQLVRNRE 94
K+ PL+ + + + K + ++ AR++E + ++ QL E
Sbjct: 835 KIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAE 894
Query: 95 QISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKL 154
Q D + D ++R + I +K + + ++ E++ + E+MN + + ++
Sbjct: 895 Q------DNLADAEERCDQLIKNKIQLEAK--VKEMNERLEDE----EEMNAELTAKKRK 942
Query: 155 LSSEMDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEY 214
L E C+E+K++ ++ L + E E EN K L E E + ++ KE
Sbjct: 943 LEDE----CSELKRDIDDLELTLAKV-EKEKHATENKVKN-LTEEMAGLDEIIAKLTKEK 996
Query: 215 KYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESG--E 272
K L+ + D + E ++ + KAK K +++ + L+Q+KK+ E E
Sbjct: 997 KALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLE 1056
Query: 273 EDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNT 332
D K+ + EN Q+ +E LK+ + L + ++ + +L + L+ L
Sbjct: 1057 GDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKK---LKELQA 1113
Query: 333 NLYYTQLELQKEKAIVGNLEKMLQTKFAETEE 364
+ + EL+ E+ +EK+ E EE
Sbjct: 1114 RIEELEEELEAERTARAKVEKLRSDLSRELEE 1145
Score = 40.0 bits (92), Expect = 0.004
Identities = 56/277 (20%), Positives = 112/277 (40%), Gaps = 48/277 (17%)
Query: 130 LEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELE 189
L+ +I +L +E+ N + K ++NF+ E K+ +E SELE
Sbjct: 1421 LQNEIEDLMVDVERSNAAAAALDK------------KQRNFDKILAEWKQKYEESQSELE 1468
Query: 190 NNYKAA--LKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDE 247
++ K A L E + EE + + K + Q+ I D E+ S K
Sbjct: 1469 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKT------ 1522
Query: 248 KFERENILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLE 307
+ + +K+ K+ E E E + E+ E ++ +E + + Q + Q++
Sbjct: 1523 --------IHELEKVRKQLEAEKMELQSALEEA-----EASLEHEEGKILRAQLEFNQIK 1569
Query: 308 -----ELRKTKEVMQEELHAQALILESLNTNL----YYTQLELQKEKAIVGNLEKM---- 354
+L + E M++ +++SL T+L L+ +K + G+L +M
Sbjct: 1570 AEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQL 1629
Query: 355 --LQTKFAETEEKYKHTIQILTEENIHLKQKIISKNE 389
AE +++ K +L + I L + + ++
Sbjct: 1630 SHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDD 1666
Score = 39.3 bits (90), Expect = 0.007
Identities = 66/287 (22%), Positives = 116/287 (40%), Gaps = 61/287 (21%)
Query: 126 IISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAEL 185
I +++E +++E +EQ R+H L + +D AE + N+ +K+ E +L
Sbjct: 1568 IKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLD---AETRS--RNEALRVKKKMEGDL 1622
Query: 186 SELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYD--------------- 230
+E+E A ++AA E K+ K L+++ + Q + D
Sbjct: 1623 NEMEIQLS---HANRMAA-----EAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIV 1674
Query: 231 ---------EMEE--------KWSKQKAKWKKDEKFERENI-------LLQQKKKMTKKF 266
E+EE + S++ A+ + E ER + L+ QKKKM
Sbjct: 1675 ERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADL 1734
Query: 267 EM------ESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEEL 320
E+ +E + E + EE LK+ Q + LE ++K E ++L
Sbjct: 1735 SQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEE-LKKEQDTSAHLERMKKNMEQTIKDL 1793
Query: 321 HAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAETEEKYK 367
Q + E+ L + +LQK +A V LE L+ + E K
Sbjct: 1794 --QHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVK 1838
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform
1 [Homo sapiens]
Length = 1722
Score = 58.2 bits (139), Expect = 1e-08
Identities = 56/233 (24%), Positives = 113/233 (48%), Gaps = 21/233 (9%)
Query: 171 ENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGK-----------EYKYLKN 219
E K R+ EA + + ELE+ K LKA++ +++ +E + E K L+N
Sbjct: 164 EEKCRQSFEAWQEKQKELEDKEKQTLKAQRDREEKQFQEEEEKRHCWMKQFKVEKKKLEN 223
Query: 220 MFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINE 279
+ + QD + DE+ ++ K K+K+ E++ R N+ LQ +++ T+ + + E++ + +
Sbjct: 224 IQKQEQDKMNDELYKEEKIWKEKFKQHEEYIR-NLHLQMEEERTRFKDQQEKEKNSLLKQ 282
Query: 280 SCSAVFENFIQEKEELLKQHQS-DTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQ 338
+A + IQ K + +Q + E++ K QE +A I + N +
Sbjct: 283 QNNAAVK--IQAKYKAFVAYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKEEEN----R 336
Query: 339 LELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHL--KQKIISKNE 389
L++E+ I +K + + E++Y+ I+ +E L K+KII + +
Sbjct: 337 KRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQEREQLISKEKIILRED 389
Score = 42.4 bits (98), Expect = 8e-04
Identities = 62/293 (21%), Positives = 128/293 (43%), Gaps = 31/293 (10%)
Query: 106 DRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAE 165
+++K E + + R +E+ + ++Q + + + + E D E
Sbjct: 176 EKQKELEDKEKQTLKAQRDREEKQFQEEEEKRHCWMKQFKVEKKKLENIQKQEQDKMNDE 235
Query: 166 M-------KQNFENKNRELKEAHEAELSELENNYKAALKAEK--LAAQEKLEEMGKEYKY 216
+ K+ F+ ++ H ++ E +K + EK L Q+ + + KY
Sbjct: 236 LYKEEKIWKEKFKQHEEYIRNLH-LQMEEERTRFKDQQEKEKNSLLKQQNNAAVKIQAKY 294
Query: 217 LKNM-FRTYQDSIYDEMEEKWSKQKAK-WKKDEKFERENILLQQKKKMTKKFEMESG--E 272
+ ++ Y I +++E K K+KA+ WK E+E + Q++++ K+ E E E
Sbjct: 295 KAFVAYQKYGPIIKEQIESK--KRKAQEWK-----EKEAKIRQKEEENRKRLEEEQRIKE 347
Query: 273 EDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNT 332
E KK E E +EK+ ++KQ + + K K +++E+ Q +I +L
Sbjct: 348 ERKKQKEEERKRREKEYEEKKNIVKQEREQLIS-----KEKIILREDASQQLIISSALKK 402
Query: 333 NLYYTQ-LELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKI 384
+ Y + L L+ G++ K L E +K + + L EE+ ++K+ +
Sbjct: 403 SGYNNKHLSLEDISNDKGDIAKNL---VDENSKKQEDVLLWLVEES-NMKENV 451
Score = 42.4 bits (98), Expect = 8e-04
Identities = 39/190 (20%), Positives = 87/190 (45%), Gaps = 22/190 (11%)
Query: 91 RNREQISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQS 150
+N +E+ +++++E+ +K +++ +L+EQ ++++ D Q
Sbjct: 483 KNENLAKKRCSEELVKQERKYENT-DNKTELGNSDLKGNLKEQFP-----LQELKSDAQK 536
Query: 151 AQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSEL--ENNYKAALKAEKLAAQEKLE 208
+K++ ++ + Q N+E+ E E ++ +N K K EK +E E
Sbjct: 537 EEKIMKHVINENTGQKTQIILGHNQEISEVKTNEEQKIIKDNQQKKIQKVEK---EEIQE 593
Query: 209 EMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEM 268
+ G YK +D++ ++++ ++ KD REN++LQ+K+ +K E+
Sbjct: 594 QNGLLYKD--------KDTLVISVKQRSLSLTSENSKDV---RENVILQEKEIYSKSKEI 642
Query: 269 ESGEEDKKIN 278
E +D N
Sbjct: 643 EENPKDNAWN 652
>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform
2 [Homo sapiens]
Length = 1336
Score = 58.2 bits (139), Expect = 1e-08
Identities = 56/233 (24%), Positives = 113/233 (48%), Gaps = 21/233 (9%)
Query: 171 ENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGK-----------EYKYLKN 219
E K R+ EA + + ELE+ K LKA++ +++ +E + E K L+N
Sbjct: 164 EEKCRQSFEAWQEKQKELEDKEKQTLKAQRDREEKQFQEEEEKRHCWMKQFKVEKKKLEN 223
Query: 220 MFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESGEEDKKINE 279
+ + QD + DE+ ++ K K+K+ E++ R N+ LQ +++ T+ + + E++ + +
Sbjct: 224 IQKQEQDKMNDELYKEEKIWKEKFKQHEEYIR-NLHLQMEEERTRFKDQQEKEKNSLLKQ 282
Query: 280 SCSAVFENFIQEKEELLKQHQS-DTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQ 338
+A + IQ K + +Q + E++ K QE +A I + N +
Sbjct: 283 QNNAAVK--IQAKYKAFVAYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKEEEN----R 336
Query: 339 LELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHL--KQKIISKNE 389
L++E+ I +K + + E++Y+ I+ +E L K+KII + +
Sbjct: 337 KRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQEREQLISKEKIILRED 389
Score = 42.4 bits (98), Expect = 8e-04
Identities = 62/293 (21%), Positives = 128/293 (43%), Gaps = 31/293 (10%)
Query: 106 DRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAE 165
+++K E + + R +E+ + ++Q + + + + E D E
Sbjct: 176 EKQKELEDKEKQTLKAQRDREEKQFQEEEEKRHCWMKQFKVEKKKLENIQKQEQDKMNDE 235
Query: 166 M-------KQNFENKNRELKEAHEAELSELENNYKAALKAEK--LAAQEKLEEMGKEYKY 216
+ K+ F+ ++ H ++ E +K + EK L Q+ + + KY
Sbjct: 236 LYKEEKIWKEKFKQHEEYIRNLH-LQMEEERTRFKDQQEKEKNSLLKQQNNAAVKIQAKY 294
Query: 217 LKNM-FRTYQDSIYDEMEEKWSKQKAK-WKKDEKFERENILLQQKKKMTKKFEMESG--E 272
+ ++ Y I +++E K K+KA+ WK E+E + Q++++ K+ E E E
Sbjct: 295 KAFVAYQKYGPIIKEQIESK--KRKAQEWK-----EKEAKIRQKEEENRKRLEEEQRIKE 347
Query: 273 EDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNT 332
E KK E E +EK+ ++KQ + + K K +++E+ Q +I +L
Sbjct: 348 ERKKQKEEERKRREKEYEEKKNIVKQEREQLIS-----KEKIILREDASQQLIISSALKK 402
Query: 333 NLYYTQ-LELQKEKAIVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKI 384
+ Y + L L+ G++ K L E +K + + L EE+ ++K+ +
Sbjct: 403 SGYNNKHLSLEDISNDKGDIAKNL---VDENSKKQEDVLLWLVEES-NMKENV 451
Score = 42.4 bits (98), Expect = 8e-04
Identities = 39/190 (20%), Positives = 87/190 (45%), Gaps = 22/190 (11%)
Query: 91 RNREQISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQS 150
+N +E+ +++++E+ +K +++ +L+EQ ++++ D Q
Sbjct: 483 KNENLAKKRCSEELVKQERKYENT-DNKTELGNSDLKGNLKEQFP-----LQELKSDAQK 536
Query: 151 AQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSEL--ENNYKAALKAEKLAAQEKLE 208
+K++ ++ + Q N+E+ E E ++ +N K K EK +E E
Sbjct: 537 EEKIMKHVINENTGQKTQIILGHNQEISEVKTNEEQKIIKDNQQKKIQKVEK---EEIQE 593
Query: 209 EMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEM 268
+ G YK +D++ ++++ ++ KD REN++LQ+K+ +K E+
Sbjct: 594 QNGLLYKD--------KDTLVISVKQRSLSLTSENSKDV---RENVILQEKEIYSKSKEI 642
Query: 269 ESGEEDKKIN 278
E +D N
Sbjct: 643 EENPKDNAWN 652
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 57.8 bits (138), Expect = 2e-08
Identities = 71/332 (21%), Positives = 142/332 (42%), Gaps = 26/332 (7%)
Query: 38 KLTPLVPAPKNHNYLQPTKPV---VSPKMKIHSARQEETNKSFYEVINVSPGYQLVRNRE 94
K+ PL+ + + + K + ++ AR++E + ++ QL E
Sbjct: 837 KIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAE 896
Query: 95 QISVTLGDEMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMNRDHQSAQKL 154
Q D + D ++R + I +K + + ++ E++ + E+MN + + ++
Sbjct: 897 Q------DNLNDAEERCDQLIKNKIQLEAK--VKEMNERLEDE----EEMNAELTAKKRK 944
Query: 155 LSSEMDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALKAEKLAAQEKLEEMGKEY 214
L E C+E+K++ ++ L + E E EN K L E E + ++ KE
Sbjct: 945 LEDE----CSELKKDIDDLELTLAKV-EKEKHATENKVKN-LTEEMAGLDEIIAKLTKEK 998
Query: 215 KYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQQKKKMTKKFEMESG--E 272
K L+ + D + E ++ S K+K K +++ + L+Q+KK+ E E
Sbjct: 999 KALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLE 1058
Query: 273 EDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEELHAQALILESLNT 332
D K+ + EN + EE LK+ + D Q + ++V+ +L + L+
Sbjct: 1059 GDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKK---LKENQA 1115
Query: 333 NLYYTQLELQKEKAIVGNLEKMLQTKFAETEE 364
+ + EL+ E+ +EK+ E EE
Sbjct: 1116 RIEELEEELEAERTARAKVEKLRSDLSRELEE 1147
Score = 41.6 bits (96), Expect = 0.001
Identities = 55/281 (19%), Positives = 122/281 (43%), Gaps = 27/281 (9%)
Query: 88 QLVRNREQISVTLGD--EMFDRKKRWESEIPDKGRFSRTNIISDLEEQISELTAIIEQMN 145
QL++N+ Q+ + + E + ++ +E+ K R + S+L++ I +L + ++
Sbjct: 909 QLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKR-KLEDECSELKKDIDDLELTLAKVE 967
Query: 146 RDHQSAQ---KLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELE---------NNYK 193
++ + + K L+ EM E+ + + L+EAH+ L +L+ + K
Sbjct: 968 KEKHATENKVKNLTEEM-AGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSK 1026
Query: 194 AALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFEREN 253
L+ + + LE+ K L+ R + + E + K + +EK +++
Sbjct: 1027 VKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKE 1086
Query: 254 ILLQQKKKMTKKFEMESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTK 313
+ Q+ + ++ + + KK+ E+ + I+E EE L+ ++ ++E+LR
Sbjct: 1087 FDINQQNSKIEDEQVLALQLQKKLKEN-----QARIEELEEELEAERTARAKVEKLRSDL 1141
Query: 314 EVMQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKM 354
EE I E L T ++++ K +KM
Sbjct: 1142 SRELEE------ISERLEEAGGATSVQIEMNKKREAEFQKM 1176
Score = 40.8 bits (94), Expect = 0.002
Identities = 67/287 (23%), Positives = 117/287 (40%), Gaps = 61/287 (21%)
Query: 126 IISDLEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAEL 185
I +++E +++E +EQ R+HQ L + +D AE + N+ +K+ E +L
Sbjct: 1570 IKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLD---AETRS--RNEVLRVKKKMEGDL 1624
Query: 186 SELENNYKAALKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYD--------------- 230
+E+E A ++AA E K+ K L+++ + Q + D
Sbjct: 1625 NEMEIQLS---HANRMAA-----EAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIV 1676
Query: 231 ---------EMEE--------KWSKQKAKWKKDEKFERENI-------LLQQKKKMTKKF 266
E+EE + S++ A+ + E ER + L+ QKKKM
Sbjct: 1677 ERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDL 1736
Query: 267 EM------ESGEEDKKINESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEVMQEEL 320
E+ +E + E + EE LK+ Q + LE ++K E ++L
Sbjct: 1737 TQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEE-LKKEQDTSAHLERMKKNMEQTIKDL 1795
Query: 321 HAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAETEEKYK 367
Q + E+ L + +LQK +A V LE L+ + E K
Sbjct: 1796 --QHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVK 1840
Score = 37.0 bits (84), Expect = 0.034
Identities = 59/278 (21%), Positives = 113/278 (40%), Gaps = 36/278 (12%)
Query: 130 LEEQISELTAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELE 189
L+ +I +L +E+ N + K ++NF+ E K+ +E SELE
Sbjct: 1423 LQNEIEDLMVDVERSNAAAAALDK------------KQRNFDKILAEWKQKYEESQSELE 1470
Query: 190 NNYKAA--LKAEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEE--KWSKQKAKWKK 245
++ K A L E + EE + + K + Q+ I D E+ + K + +K
Sbjct: 1471 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEK 1530
Query: 246 DEK-FERENILLQQK-KKMTKKFEMESGEEDKKINE--SCSAVFENFIQEKEELLKQ--- 298
K E E + LQ ++ E E G+ + E A E + EK+E ++Q
Sbjct: 1531 VRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1590
Query: 299 -HQ-----------SDTLQLEELRKTKEVMQEELHAQALILESLNTNLYYTQLELQKEKA 346
HQ ++T E+ + K+ M+ +L+ + L N Q +++ ++
Sbjct: 1591 NHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQS 1650
Query: 347 IVGNLEKMLQTKFAETEEKYKHTIQILTEENIHLKQKI 384
++ + + L + K I I+ N L+ ++
Sbjct: 1651 LLKDTQIQLDDA-VRANDDLKENIAIVERRNNLLQAEL 1687
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.348
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,952,736
Number of Sequences: 37866
Number of extensions: 761868
Number of successful extensions: 7443
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 194
Number of HSP's successfully gapped in prelim test: 856
Number of HSP's that attempted gapping in prelim test: 3993
Number of HSP's gapped (non-prelim): 2670
length of query: 422
length of database: 18,247,518
effective HSP length: 105
effective length of query: 317
effective length of database: 14,271,588
effective search space: 4524093396
effective search space used: 4524093396
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.